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题目:: The effect of fenofibrate on endothelial cells
ID:
状态:: 发布时间May 6, 2010 , 更新时间 March 27, 2012 , 提交时间 March 30, 2009,
物种:: Homo sapiens
摘要:: Fenofibrate is a synthetic ligand for the nuclear receptor peroxisome proliferator-activated receptor (PPAR) alpha, but there are reports that fenofibrate affects endothelial cells in PPARa-independent manner. In order to identify PPARa-dependently and PPARa-independently regulated transcripts we generated microarray data from human endothelial cells treated with fenofibrate with and without siRNA-mediated knock-down of PPARa. In this study, we generated microarray data from human umbilical vein endothelial cells (HUVECs) treated with fenofibrate. Time 0 indicates the start point of observation immediately prior to exposure to the 25umol fenofibrate. There are five time points (2, 4, 6, 8, and 18hours) (n=3 at each time point). The control is untreatment HUVEC (n=4).
实验种类:: transcription profiling by array
样本量:: 19
实验设计:
: 无设计数据
数据号:: E-GEOD-15483, GSE15483
数据状态:: 无法自动分析，您可以尝试手动分析数据。

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