NFKB1基因详情-基因数据库-基因云馆

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NFKB1 (nuclear factor kappa B subunit 1)

symbol:: NFKB1
locus group:: protein-coding gene
location:: 4q24
gene_family:: Ankyrin repeat domain containing
alias symbol:: KBF1|p105|NFKB-p50|p50|NF-kappaB|NFkappaB|NF-kB1
alias name:: Nuclear factor NF-kappa-B p105 sub…
entrez id:: 4790
ensembl gene id:: ENSG00000109320
ucsc gene id:: uc011cep.2
refseq accession:: NM_003998
hgnc_id:: HGNC:7794
approved reserved:: 1991-11-14

4q24

NFKB1是核因子κB（NF-κB）家族的重要成员，编码p105蛋白，经加工后形成具有活性的p50亚基。NF-κB家族是一类广泛参与免疫、炎症、细胞增殖和凋亡调控的转录因子，其共性在于通过形成同源或异源二聚体结合DNA，调控下游靶基因表达。NFKB1主要通过与Rel家族蛋白（如RelA/p65）形成p50-RelA异源二聚体发挥作用，这种复合物是经典的NF-κB激活形式。在静息状态下，NF-κB被IκB蛋白抑制而滞留于胞质；当受到TNF-α、IL-1等刺激时，IκB被降解，NF-κB入核激活靶基因，如促炎细胞因子（IL-6、TNF-α）和抗凋亡蛋白（Bcl-2）。NFKB1的突变可能导致免疫缺陷或异常炎症反应，如杂合突变与常见可变免疫缺陷病（CVID）相关，表现为抗体产生障碍和反复感染。其功能丧失还可能影响B细胞发育和淋巴器官形成。NFKB1过表达会持续激活促炎通路，与类风湿关节炎、炎症性肠病和多种癌症（如淋巴瘤、乳腺癌）的发生发展密切相关；而表达降低则可能导致免疫应答缺陷，增加感染风险。值得注意的是，p50同源二聚体缺乏转录激活域，反而可能抑制某些炎症基因的表达，形成负反馈调节。该基因还参与氧化应激反应、昼夜节律调控等过程，并与阿尔茨海默病中神经炎症的进展相关。药物开发中常以NF-κB通路为靶点，但需谨慎平衡其促炎和抗凋亡的双重作用。

This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

该基因编码一个105 kD的蛋白质被26S蛋白酶体产生50 kD的蛋白质，可以经过共翻译加工。所述的105kD蛋白质是相对特异性蛋白转录抑制剂和50 kD的蛋白质是NF-κ-B（NFKB）蛋白质复合物的DNA结合亚基。的NFκB是受各种内和细胞外刺激如细胞因子，不含氧化剂，自由基，紫外线照射，以及细菌或病毒产品激活的转录调节子。激活的NFκB易位到细胞核并刺激参与多种生物功能的基因的表达。 NFKB的不适当的激活已经与一些炎症性疾病，而NFκB的持续抑制导致不适当的免疫细胞发育或延迟细胞生长有瓜葛。已发现该基因编码不同亚型的两个转录变异体。 [由RefSeq的，2009年09月提供]

OMIM数据库中对NFKB1基因的介绍 Wikipedia数据库中对NFKB1基因的介绍

NFKB1基因的碱基序列：[NCBI]

Loading Gene Browser...

NFKB1基因的碱基突变：仅显示部分snp

rs1801 rs230491 rs230492 rs230493 rs230494 rs230495 rs230496 rs230497 rs230498 rs230499 rs230500 rs230501 rs230502 rs230503 rs230504 rs230505 rs230538

NFKB1基因在不同组织中的表达： [UniProt]

正向引物序列

正向Tm值

反向引物序列

反向Tm值

评分

AAATCTGCAACTATGTGGGA

AGATCCCATCCTCACAGTG

AAGAAGTCTTACCCTCAGGTC

GAACAATAACCTTTGCTGGTC

AAGAAGTCTTACCCTCAGGTC

GAACAATAACCTTTGCTGGTC

TCCATATTTGGGAAGGCCT

TGAAGGTATGGGCCATCTG

TAAAGAAGCTTCAGAATGGCAG

TGAAGGTATGGGCCATCTG

TGTAAGAATGGACAGGACAG

GAATCTGGATGTCATCTTTCTG

CCATCTATGACAGTAAAGCCC

AAATCCTTCCCAGACTCCA

TCCATATTTGGGAAGGCCT

TGAAGGTATGGGCCATCTG

AAAGAACCACCAGCTTCAG

CTGTGGTTGAAATACTTCTGGA

GACAACTATGAGGTCTCTGGG

TTCAATTGCTTCGGTGTAGC

转录因子

影响基因

影响类型

参考文献链接（PubMed）

APEX1

NFKB1

Activation

17045925

NFKB1

Repression

18386814

BCL3

NFKB1

Repression

11387332

BCL3

NFKB1

Unknown

14573596; 7896265

BCL6

NFKB1

Repression

15611242

BTF3

NFKB1

Repression

17312387

EGR1

NFKB1

Unknown

10671503

EP300

NFKB1

Unknown

9560267

ETV3

NFKB1

Repression

18025162

FHL2

NFKB1

Unknown

18752053

NFKB1基因（以及对应的蛋白质）的细胞分布位置：

[UniProt] [GenomeNet]

质膜
细胞质
细胞外
高尔基体
囊泡
细胞骨架
内质网
细胞核
内体
溶酶体
线粒体

NFKB1基因的本体（GO）信息：

GO库代码

对应的蛋白质

来源代码

GO:0003677

D6RC45 (UniProtKB)

IEA

GO:0003700

D6RC45 (UniProtKB)

IEA

GO:0005634

D6RC45 (UniProtKB)

IEA

GO:0005737

D6RC45 (UniProtKB)

IEA

GO:0006357

D6RC45 (UniProtKB)

IEA

GO:0003677

D6RDI9 (UniProtKB)

IEA

GO:0003700

D6RDI9 (UniProtKB)

IEA

GO:0005634

D6RDI9 (UniProtKB)

IEA

GO:0005737

D6RDI9 (UniProtKB)

IEA

GO:0006357

D6RDI9 (UniProtKB)

IEA

GO:0003677

D6RF93 (UniProtKB)

IEA

GO:0003700

D6RF93 (UniProtKB)

IEA

GO:0005634

D6RF93 (UniProtKB)

IEA

GO:0005737

D6RF93 (UniProtKB)

IEA

GO:0006357

D6RF93 (UniProtKB)

IEA

GO:0003677

D6RH30 (UniProtKB)

IEA

GO:0003700

D6RH30 (UniProtKB)

IEA

GO:0005634

D6RH30 (UniProtKB)

IEA

GO:0005737

D6RH30 (UniProtKB)

IEA

GO:0006357

D6RH30 (UniProtKB)

IEA

GO:0000122

P19838 (UniProtKB)

GO:0000122

P19838 (UniProtKB)

IMP

GO:0000122

P19838 (UniProtKB)

IGI

GO:0000975

P19838 (UniProtKB)

IDA

GO:0000976

P19838 (UniProtKB)

IDA

GO:0000977

P19838 (UniProtKB)

IDA

GO:0000980

P19838 (UniProtKB)

IDA

GO:0001205

P19838 (UniProtKB)

IDA

GO:0001227

P19838 (UniProtKB)

IDA

GO:0002223

P19838 (UniProtKB)

TAS

GO:0003682

P19838 (UniProtKB)

IBA

GO:0003700

P19838 (UniProtKB)

IDA

GO:0005515

P19838 (UniProtKB)

IPI

GO:0005515

P19838 (UniProtKB)

IPI

GO:0005515

P19838 (UniProtKB)

IPI

GO:0005515

P19838 (UniProtKB)

IPI

GO:0005515

P19838 (UniProtKB)

IPI

GO:0005515

P19838 (UniProtKB)

IPI

GO:0005515

P19838 (UniProtKB)

IPI

GO:0005515

P19838 (UniProtKB)

IPI

GO:0005515

P19838 (UniProtKB)

IPI

GO:0005515

P19838 (UniProtKB)

IPI

GO:0005515

P19838 (UniProtKB)

IPI

GO:0005515

P19838 (UniProtKB)

IPI

GO:0005515

P19838 (UniProtKB)

IPI

GO:0005515

P19838 (UniProtKB)

IPI

GO:0005515

P19838 (UniProtKB)

IPI

GO:0005515

P19838 (UniProtKB)

IPI

GO:0005515

P19838 (UniProtKB)

IPI

GO:0005515

P19838 (UniProtKB)

IPI

GO:0005515

P19838 (UniProtKB)

IPI

GO:0005515

P19838 (UniProtKB)

IPI

GO:0005515

P19838 (UniProtKB)

IPI

GO:0005515

P19838 (UniProtKB)

IPI

GO:0005515

P19838 (UniProtKB)

IPI

GO:0005515

P19838 (UniProtKB)

IPI

GO:0005515

P19838 (UniProtKB)

IPI

GO:0005515

P19838 (UniProtKB)

IPI

GO:0005515

P19838 (UniProtKB)

IPI

GO:0005515

P19838 (UniProtKB)

IPI

GO:0005515

P19838 (UniProtKB)

IPI

GO:0005515

P19838 (UniProtKB)

IPI

GO:0005515

P19838 (UniProtKB)

IPI

GO:0005515

P19838 (UniProtKB)

IPI

GO:0005515

P19838 (UniProtKB)

IPI

GO:0005515

P19838 (UniProtKB)

IPI

GO:0005515

P19838 (UniProtKB)

IPI

GO:0005515

P19838 (UniProtKB)

IPI

GO:0005515

P19838 (UniProtKB)

IPI

GO:0005515

P19838 (UniProtKB)

IPI

GO:0005515

P19838 (UniProtKB)

IPI

GO:0005515

P19838 (UniProtKB)

IPI

GO:0005515

P19838 (UniProtKB)

IPI

GO:0005515

P19838 (UniProtKB)

IPI

GO:0005515

P19838 (UniProtKB)

IPI

GO:0005515

P19838 (UniProtKB)

IPI

GO:0005515

P19838 (UniProtKB)

IPI

GO:0005515

P19838 (UniProtKB)

IPI

GO:0005515

P19838 (UniProtKB)

IPI

GO:0005515

P19838 (UniProtKB)

IPI

GO:0005515

P19838 (UniProtKB)

IPI

GO:0005515

P19838 (UniProtKB)

IPI

GO:0005515

P19838 (UniProtKB)

IPI

GO:0005515

P19838 (UniProtKB)

IPI

GO:0005515

P19838 (UniProtKB)

IPI

GO:0005515

P19838 (UniProtKB)

IPI

GO:0005515

P19838 (UniProtKB)

IPI

GO:0005515

P19838 (UniProtKB)

IPI

GO:0005515

P19838 (UniProtKB)

IPI

GO:0005515

P19838 (UniProtKB)

IPI

GO:0005515

P19838 (UniProtKB)

IPI

GO:0005515

P19838 (UniProtKB)

IPI

GO:0005515

P19838 (UniProtKB)

IPI

GO:0005515

P19838 (UniProtKB)

IPI

GO:0005515

P19838 (UniProtKB)

IPI

GO:0005515

P19838 (UniProtKB)

IPI

GO:0005515

P19838 (UniProtKB)

IPI

GO:0005634

P19838 (UniProtKB)

IDA

GO:0005634

P19838 (UniProtKB)

IDA

GO:0005654

P19838 (UniProtKB)

IDA

GO:0005654

P19838 (UniProtKB)

TAS

GO:0005654

P19838 (UniProtKB)

TAS

GO:0005654

P19838 (UniProtKB)

TAS

GO:0005654

P19838 (UniProtKB)

TAS

GO:0005654

P19838 (UniProtKB)

TAS

GO:0005654

P19838 (UniProtKB)

TAS

GO:0005654

P19838 (UniProtKB)

TAS

GO:0005654

P19838 (UniProtKB)

TAS

GO:0005654

P19838 (UniProtKB)

TAS

GO:0005737

P19838 (UniProtKB)

IDA

GO:0005737

P19838 (UniProtKB)

IDA

GO:0005739

P19838 (UniProtKB)

IDA

GO:0005829

P19838 (UniProtKB)

IBA

GO:0005829

P19838 (UniProtKB)

TAS

GO:0005829

P19838 (UniProtKB)

TAS

GO:0005829

P19838 (UniProtKB)

TAS

GO:0005829

P19838 (UniProtKB)

TAS

GO:0005829

P19838 (UniProtKB)

TAS

GO:0005829

P19838 (UniProtKB)

TAS

GO:0005829

P19838 (UniProtKB)

TAS

GO:0005829

P19838 (UniProtKB)

TAS

GO:0005829

P19838 (UniProtKB)

TAS

GO:0005829

P19838 (UniProtKB)

TAS

GO:0005829

P19838 (UniProtKB)

TAS

GO:0005829

P19838 (UniProtKB)

TAS

GO:0005829

P19838 (UniProtKB)

TAS

GO:0005829

P19838 (UniProtKB)

TAS

GO:0005829

P19838 (UniProtKB)

TAS

GO:0005829

P19838 (UniProtKB)

TAS

GO:0005829

P19838 (UniProtKB)

TAS

GO:0005829

P19838 (UniProtKB)

TAS

GO:0005829

P19838 (UniProtKB)

TAS

GO:0005829

P19838 (UniProtKB)

TAS

GO:0005829

P19838 (UniProtKB)

TAS

GO:0005829

P19838 (UniProtKB)

TAS

GO:0005829

P19838 (UniProtKB)

TAS

GO:0006366

P19838 (UniProtKB)

TAS

GO:0006915

P19838 (UniProtKB)

IEA

GO:0006954

P19838 (UniProtKB)

TAS

GO:0006979

P19838 (UniProtKB)

IEA

GO:0007249

P19838 (UniProtKB)

IBA

GO:0008134

P19838 (UniProtKB)

IDA

GO:0010744

P19838 (UniProtKB)

GO:0010884

P19838 (UniProtKB)

GO:0010956

P19838 (UniProtKB)

IDA

GO:0010957

P19838 (UniProtKB)

GO:0031072

P19838 (UniProtKB)

IEA

GO:0031293

P19838 (UniProtKB)

TAS

GO:0032269

P19838 (UniProtKB)

GO:0032375

P19838 (UniProtKB)

GO:0032481

P19838 (UniProtKB)

TAS

GO:0033256

P19838 (UniProtKB)

TAS

GO:0035994

P19838 (UniProtKB)

IEA

GO:0038061

P19838 (UniProtKB)

IBA

GO:0038095

P19838 (UniProtKB)

TAS

GO:0042802

P19838 (UniProtKB)

IPI

GO:0042802

P19838 (UniProtKB)

IPI

GO:0042802

P19838 (UniProtKB)

IPI

GO:0042803

P19838 (UniProtKB)

IEA

GO:0042803

P19838 (UniProtKB)

IEA

GO:0042805

P19838 (UniProtKB)

IPI

GO:0043005

P19838 (UniProtKB)

IEA

GO:0043066

P19838 (UniProtKB)

TAS

GO:0043066

P19838 (UniProtKB)

TAS

GO:0044212

P19838 (UniProtKB)

IDA

GO:0045083

P19838 (UniProtKB)

IEA

GO:0045087

P19838 (UniProtKB)

IBA

GO:0045893

P19838 (UniProtKB)

IDA

GO:0045893

P19838 (UniProtKB)

IMP

GO:0045893

P19838 (UniProtKB)

NAS

GO:0045944

P19838 (UniProtKB)

IDA

GO:0045944

P19838 (UniProtKB)

IMP

GO:0046688

P19838 (UniProtKB)

IEA

GO:0046982

P19838 (UniProtKB)

IDA

GO:0046982

P19838 (UniProtKB)

IDA

GO:0050728

P19838 (UniProtKB)

IEA

GO:0050852

P19838 (UniProtKB)

TAS

GO:0051092

P19838 (UniProtKB)

TAS

GO:0051403

P19838 (UniProtKB)

TAS

GO:0071222

P19838 (UniProtKB)

IMP

GO:0071260

P19838 (UniProtKB)

IEP

GO:0071316

P19838 (UniProtKB)

IMP

GO:0071322

P19838 (UniProtKB)

IEA

GO:0071347

P19838 (UniProtKB)

IEP

GO:0071354

P19838 (UniProtKB)

IMP

GO:0071356

P19838 (UniProtKB)

IEA

GO:0071359

P19838 (UniProtKB)

IEA

GO:0071375

P19838 (UniProtKB)

IMP

GO:0090263

P19838 (UniProtKB)

IMP

GO:1900127

P19838 (UniProtKB)

IDA

GO:1904630

P19838 (UniProtKB)

IEA

GO:1904632

P19838 (UniProtKB)

IEA

GO:1990416

P19838 (UniProtKB)

IEA

GO:2000630

P19838 (UniProtKB)

IMP

可能调控 NFKB1基因的相关microRNA：

hsa-miR-155 hsa-miR-26b hsa-miR-9 hsa-let-7a hsa-let-7b hsa-let-7b* hsa-let-7c hsa-let-7c* hsa-let-7d hsa-let-7d*

Reactome

MINT

BioGrid

IntAct

mentha

String

序号	作用方式	资源库来源/分值	基因名称	基因名称

KEGG
Reactomepathway

名称
4014 Ras signaling pathway [PATH:hsa04014]
4010 MAPK signaling pathway [PATH:hsa04010]
4064 NF-kappa B signaling pathway [PATH:hsa04064]
4668 TNF signaling pathway [PATH:hsa04668]
4066 HIF-1 signaling pathway [PATH:hsa04066]
4071 Sphingolipid signaling pathway [PATH:hsa04071]
4024 cAMP signaling pathway [PATH:hsa04024]
4151 PI3K-Akt signaling pathway [PATH:hsa04151]
4210 Apoptosis [PATH:hsa04210]
4620 Toll-like receptor signaling pathway [PATH:hsa04620]
4621 NOD-like receptor signaling pathway [PATH:hsa04621]
4622 RIG-I-like receptor signaling pathway [PATH:hsa04622]
4623 Cytosolic DNA-sensing pathway [PATH:hsa04623]
4660 T cell receptor signaling pathway [PATH:hsa04660]
4662 B cell receptor signaling pathway [PATH:hsa04662]
4062 Chemokine signaling pathway [PATH:hsa04062]
4920 Adipocytokine signaling pathway [PATH:hsa04920]
4917 Prolactin signaling pathway [PATH:hsa04917]
4722 Neurotrophin signaling pathway [PATH:hsa04722]
4380 Osteoclast differentiation [PATH:hsa04380]
5200 Pathways in cancer [PATH:hsa05200]
5202 Transcriptional misregulation in cancers [PATH:hsa05202]
5206 MicroRNAs in cancer [PATH:hsa05206]
5203 Viral carcinogenesis [PATH:hsa05203]
5212 Pancreatic cancer [PATH:hsa05212]
5221 Acute myeloid leukemia [PATH:hsa05221]
5220 Chronic myeloid leukemia [PATH:hsa05220]
5215 Prostate cancer [PATH:hsa05215]
5222 Small cell lung cancer [PATH:hsa05222]
5321 Inflammatiory bowel disease (IBD) [PATH:hsa05321]
5030 Cocaine addiction [PATH:hsa05030]
4932 Non-alcoholic fatty liver disease (NAFLD) [PATH:hsa04932]
5120 Epithelial cell signaling in Helicobacter pylori infection [PATH:hsa05120]
5132 Salmonella infection [PATH:hsa05132]
5131 Shigellosis [PATH:hsa05131]
5133 Pertussis [PATH:hsa05133]
5134 Legionellosis [PATH:hsa05134]
5152 Tuberculosis [PATH:hsa05152]
5166 HTLV-I infection [PATH:hsa05166]
5162 Measles [PATH:hsa05162]
5164 Influenza A [PATH:hsa05164]
5161 Hepatitis B [PATH:hsa05161]
5160 Hepatitis C [PATH:hsa05160]
5168 Herpes simplex infection [PATH:hsa05168]
5169 Epstein-Barr virus infection [PATH:hsa05169]
5146 Amoebiasis [PATH:hsa05146]
5145 Toxoplasmosis [PATH:hsa05145]
5140 Leishmaniasis [PATH:hsa05140]
5142 Chagas disease (American trypanosomiasis) [PATH:hsa05142]

名称
Activated TLR4 signalling
Activation of NF-kappaB in B cells
Adaptive Immune System
C-type lectin receptors (CLRs)
CD209 (DC-SIGN) signaling
Cellular responses to stress
Cellular Senescence
CLEC7A (Dectin-1) signaling
CLEC7A/inflammasome pathway
Cytokine Signaling in Immune system
Cytosolic sensors of pathogen-associated DNA
Developmental Biology
DEx/H-box helicases activate type I IFN and inflammatory cytokines production
Disease
Diseases associated with the TLR signaling cascade
Diseases of Immune System
Downstream signaling events of B Cell Receptor (BCR)
Downstream TCR signaling
Fc epsilon receptor (FCERI) signaling
FCERI mediated NF-kB activation
IkBA variant leads to EDA-ID
IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR)
Immune System
Innate Immune System
Interleukin-1 processing
Interleukin-1 signaling
MyD88 cascade initiated on plasma membrane
MyD88 dependent cascade initiated on endosome
MyD88-independent TLR3/TLR4 cascade
MyD88:Mal cascade initiated on plasma membrane
NF-kB is activated and signals survival
p75 NTR receptor-mediated signalling
p75NTR signals via NF-kB
Regulated proteolysis of p75NTR
RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
RIP-mediated NFkB activation via ZBP1
Senescence-Associated Secretory Phenotype (SASP)
Signaling by Interleukins
Signaling by the B Cell Receptor (BCR)
Signalling by NGF
TAK1 activates NFkB by phosphorylation and activation of IKKs complex
TCR signaling
Toll Like Receptor 10 (TLR10) Cascade
Toll Like Receptor 2 (TLR2) Cascade
Toll Like Receptor 3 (TLR3) Cascade
Toll Like Receptor 4 (TLR4) Cascade
Toll Like Receptor 5 (TLR5) Cascade
Toll Like Receptor 7/8 (TLR7/8) Cascade
Toll Like Receptor 9 (TLR9) Cascade
Toll Like Receptor TLR1:TLR2 Cascade
Toll Like Receptor TLR6:TLR2 Cascade
Toll-Like Receptors Cascades
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
TRAF6 Mediated Induction of proinflammatory cytokines
TRAF6 mediated NF-kB activation
Transcriptional regulation of white adipocyte differentiation
TRIF-mediated TLR3/TLR4 signaling
ZBP1(DAI) mediated induction of type I IFNs

疾病名称

关系值

NofPmids

NofSnps

来源

疾病名称	关系值	NofPmids	NofSnps	来源
Adenocarcinoma	0.138713133	8	0	CTD_human_GAD_LHGDN
Schizophrenia	0.134581916	46	1	BeFree_GAD_GWASCAT
Colonic Neoplasms	0.131354408	9	0	BeFree_CTD_human_GAD_LHGDN
Ulcerative Colitis	0.1312586	16	33	BeFree_GAD_GWASCAT_LHGDN
Diabetes Mellitus, Non-Insulin-Dependent	0.127448483	13	1	BeFree_CTD_human_GAD
Biliary cirrhosis	0.122367032	1	1	CTD_human_GAD
Common Variable Immunodeficiency	0.120814326	3	0	BeFree_ORPHANET
Kidney Failure, Chronic	0.120542884	3	0	BeFree_CTD_human
Liver diseases	0.120271442	2	0	BeFree_CTD_human
Brain Ischemia	0.120271442	2	0	BeFree_CTD_human

联系方式

山东省济南市章丘区文博路2号齐鲁师范学院 genelibs生信实验室

山东省济南市高新区舜华路750号大学科技园北区F座4单元2楼

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E-mail: product@genelibs.com

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更新于2天前

NFKB1 (nuclear factor kappa B subunit 1)

基因基本信息

基因基本信息

基因染色体位置

基因染色体位置

基因简述

基因简述

基因序列

基因序列

基因突变

基因突变

基因表达

基因表达

基因引物

基因引物

转录因子

转录因子

基因本体信息

基因相关microRNA

基因相关microRNA

基因相互作用关系

基因相互作用关系

基因通路

基因通路

基因相关疾病

基因相关疾病

基因相关服务

基因相关服务

联系方式

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