Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	isArtifactMode	oxoGCut	pox	pox_cutoff	qox	t_alt_count	t_ref_count	validation_alt_allele	validation_tumor_sample							
KIAA0467	23334	broad.mit.edu	37	1	43893772	43893772	+	Missense_Mutation	SNP	A	A	G			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr1:43893772A>G	uc001cjk.1	+	12	1667	c.1205A>G	c.(1204-1206)CAG>CGG	p.Q402R		NM_015284	NP_056099	Q5T011	SZT2_HUMAN	hypothetical protein LOC23334	1301						peroxisome					0	all_hematologic(146;0.0958)|Acute lymphoblastic leukemia(166;0.155)	Myeloproliferative disorder(586;0.0505)				GAGCATGCACAGCGGTGCTAT	0.637		NaN											0	0	0	0.019004	0	34	69									
KANK4	163782	broad.mit.edu	37	1	62740332	62740332	+	Silent	SNP	G	G	A			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr1:62740332G>A	uc001dah.3	-	3	821	c.444C>T	c.(442-444)GCC>GCT	p.A148A	KANK4_uc001dai.3_Intron|KANK4_uc001dag.3_5'Flank	NM_181712	NP_859063	Q5T7N3	KANK4_HUMAN	ankyrin repeat domain 38	148										ovary(3)|skin(2)|lung(1)	6						AAGTGAGCTCGGCATCCTCTG	0.627		NaN											0	0	0	0.012319	0	21	47									
LEPR	3953	broad.mit.edu	37	1	66075760	66075760	+	Missense_Mutation	SNP	C	C	A			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr1:66075760C>A	uc001dci.2	+	13	2085	c.1883C>A	c.(1882-1884)CCA>CAA	p.P628Q	LEPR_uc001dcg.2_Missense_Mutation_p.P628Q|LEPR_uc001dch.2_Missense_Mutation_p.P628Q|LEPR_uc009waq.2_Intron|LEPR_uc001dcj.2_Missense_Mutation_p.P628Q|LEPR_uc001dck.2_Missense_Mutation_p.P628Q	NM_002303	NP_002294	P48357	LEPR_HUMAN	leptin receptor isoform 1	628	Extracellular (Potential).|Fibronectin type-III 2.				energy reserve metabolic process|multicellular organismal development	extracellular region|integral to membrane|plasma membrane	cytokine receptor activity			skin(1)	1				OV - Ovarian serous cystadenocarcinoma(397;0.00722)|KIRC - Kidney renal clear cell carcinoma(1967;0.094)		TGGAGCAATCCAGCCTACACA	0.423		NaN											1	0	4.88506e-25	0.01441	5.47362e-25	60	71									
IGSF9	57549	broad.mit.edu	37	1	159898436	159898436	+	Silent	SNP	G	G	A			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr1:159898436G>A	uc001fur.2	-	19	2940	c.2742C>T	c.(2740-2742)CCC>CCT	p.P914P	IGSF9_uc001fuq.2_Silent_p.P898P|IGSF9_uc001fup.2_Silent_p.P60P	NM_001135050	NP_001128522	Q9P2J2	TUTLA_HUMAN	immunoglobulin superfamily, member 9 isoform a	914	Pro-rich.|Cytoplasmic (Potential).					cell junction|integral to membrane|synapse				ovary(2)|central_nervous_system(2)|large_intestine(1)	5	all_hematologic(112;0.0597)	Breast(1374;0.000126)	BRCA - Breast invasive adenocarcinoma(70;0.111)			GCAAGGGACTGGGTGGGGCTG	0.652		NaN											0	0	0	0.014758	0	5	9									
NCF2	4688	broad.mit.edu	37	1	183559371	183559371	+	Missense_Mutation	SNP	C	C	T			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr1:183559371C>T	uc001gqj.3	-	1	369	c.94G>A	c.(94-96)GTC>ATC	p.V32I	NCF2_uc010pod.1_Missense_Mutation_p.V32I|NCF2_uc010poe.1_Missense_Mutation_p.V32I|NCF2_uc001gqk.3_Missense_Mutation_p.V32I	NM_000433	NP_000424	P19878	NCF2_HUMAN	neutrophil cytosolic factor 2	32					cellular defense response|innate immune response|respiratory burst|superoxide anion generation	NADPH oxidase complex|nucleolus	electron carrier activity|protein C-terminus binding			ovary(3)	3						GGGTCCTGGACGGCACTGAAG	0.557		NaN											0	0	0	0.01441	0	98	132									
TMEM63A	9725	broad.mit.edu	37	1	226044658	226044658	+	Silent	SNP	G	G	A			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr1:226044658G>A	uc001hpm.1	-	16	1687	c.1437C>T	c.(1435-1437)CTC>CTT	p.L479L		NM_014698	NP_055513	O94886	TM63A_HUMAN	transmembrane protein 63A	479	Helical; (Potential).					integral to membrane|lysosomal membrane	nucleotide binding			ovary(1)|breast(1)	2	Breast(184;0.197)					CAATGGAGGGGAGCAGGGCCG	0.597		NaN											0	0	0	0.016522	0	18	29									
KIF26B	55083	broad.mit.edu	37	1	245582982	245582982	+	Silent	SNP	G	G	T			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr1:245582982G>T	uc001ibf.1	+	4	1541	c.1101G>T	c.(1099-1101)TCG>TCT	p.S367S	KIF26B_uc010pyq.1_Silent_p.S367S	NM_018012	NP_060482	Q2KJY2	KI26B_HUMAN	kinesin family member 26B	367					microtubule-based movement	cytoplasm|microtubule	ATP binding|microtubule motor activity			ovary(3)	3	all_cancers(71;3.86e-05)|all_epithelial(71;0.000121)|Ovarian(71;0.0412)|all_lung(81;0.0498)|Lung NSC(105;0.0708)|Breast(184;0.127)		OV - Ovarian serous cystadenocarcinoma(106;0.022)			TCCCAGCCTCGCAGGGCTCCT	0.587		NaN											1	0	1.36615e-20	0.013726	1.51252e-20	34	94									
ARHGAP22	58504	broad.mit.edu	37	10	49658321	49658321	+	Nonsense_Mutation	SNP	G	G	C			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr10:49658321G>C	uc001jgt.2	-	9	2148	c.1851C>G	c.(1849-1851)TAC>TAG	p.Y617*	ARHGAP22_uc001jgs.2_Nonsense_Mutation_p.Y527*|ARHGAP22_uc001jgu.2_Nonsense_Mutation_p.Y633*|ARHGAP22_uc010qgl.1_Nonsense_Mutation_p.Y574*|ARHGAP22_uc010qgm.1_Nonsense_Mutation_p.Y623*|ARHGAP22_uc001jgv.2_Nonsense_Mutation_p.Y315*|ARHGAP22_uc001jgr.2_Nonsense_Mutation_p.Y334*	NM_021226	NP_067049	Q7Z5H3	RHG22_HUMAN	Rho GTPase activating protein 2	617	Potential.				angiogenesis|cell differentiation|regulation of small GTPase mediated signal transduction|regulation of transcription, DNA-dependent|small GTPase mediated signal transduction|transcription, DNA-dependent	cytosol|nucleus	GTPase activator activity			ovary(1)	1						CACTCCTCTCGTACTCAGTCC	0.687		NaN											0	0	0	0.024245	0	14	3									
PCDH15	65217	broad.mit.edu	37	10	56077173	56077173	+	Missense_Mutation	SNP	C	C	T			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr10:56077173C>T	uc001jju.1	-	8	1129	c.734G>A	c.(733-735)CGA>CAA	p.R245Q	PCDH15_uc010qhq.1_Missense_Mutation_p.R250Q|PCDH15_uc010qhr.1_Missense_Mutation_p.R245Q|PCDH15_uc010qhs.1_Missense_Mutation_p.R250Q|PCDH15_uc010qht.1_Missense_Mutation_p.R245Q|PCDH15_uc010qhu.1_Missense_Mutation_p.R245Q|PCDH15_uc001jjv.1_Missense_Mutation_p.R223Q|PCDH15_uc010qhv.1_Missense_Mutation_p.R245Q|PCDH15_uc010qhw.1_Missense_Mutation_p.R208Q|PCDH15_uc010qhx.1_Missense_Mutation_p.R245Q|PCDH15_uc010qhy.1_Missense_Mutation_p.R250Q|PCDH15_uc010qhz.1_Missense_Mutation_p.R245Q|PCDH15_uc010qia.1_Missense_Mutation_p.R223Q|PCDH15_uc010qib.1_Missense_Mutation_p.R223Q|PCDH15_uc001jjw.2_Missense_Mutation_p.R245Q	NM_033056	NP_149045	Q96QU1	PCD15_HUMAN	protocadherin 15 isoform CD1-4 precursor	245	Extracellular (Potential).|Cadherin 2.				equilibrioception|homophilic cell adhesion|photoreceptor cell maintenance|sensory perception of sound	extracellular region|extracellular space|integral to membrane|photoreceptor outer segment|plasma membrane|stereocilium|synapse	calcium ion binding			pancreas(5)|ovary(4)|upper_aerodigestive_tract(2)|skin(2)	13		Melanoma(3;0.117)|Lung SC(717;0.238)				GGTGGTGGTTCGCCTCTCATT	0.413		NaN								HNSCC(58;0.16)			0	0	0	0.01441	0	60	19									
FRG2B	441581	broad.mit.edu	37	10	135438800	135438800	+	Missense_Mutation	SNP	G	G	A			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr10:135438800G>A	uc010qvg.1	-	4	693	c.640C>T	c.(640-642)CGG>TGG	p.R214W		NM_001080998	NP_001074467	Q96QU4	FRG2B_HUMAN	FSHD region gene 2 family, member B	214						nucleus					0		all_cancers(35;7.01e-07)|all_epithelial(44;1.45e-05)|Lung NSC(174;0.027)|all_lung(145;0.0384)|all_neural(114;0.0726)|Glioma(114;0.172)|Melanoma(40;0.175)		OV - Ovarian serous cystadenocarcinoma(35;1.12e-06)|all cancers(32;1.43e-06)|Epithelial(32;1.71e-06)		AGAGGCCCCCGGAGCCGAGTG	0.582		NaN											0	0	0	0.030466	0	37	27									
OR51A2	401667	broad.mit.edu	37	11	4976491	4976491	+	Silent	SNP	G	G	T			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr11:4976491G>T	uc010qyt.1	-	1	453	c.453C>A	c.(451-453)TCC>TCA	p.S151S		NM_001004748	NP_001004748	Q8NGJ7	O51A2_HUMAN	olfactory receptor, family 51, subfamily A,	151	Helical; Name=4; (Potential).				sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity				0		Medulloblastoma(188;0.0075)|all_neural(188;0.0577)|Breast(177;0.086)		Epithelial(150;3.22e-11)|BRCA - Breast invasive adenocarcinoma(625;0.0284)|LUSC - Lung squamous cell carcinoma(625;0.19)		TGCTCTTAAAGGAGAATACTA	0.423		NaN											1	0	9.62906e-15	0.025465	1.04128e-14	35	97									
CST6	1474	broad.mit.edu	37	11	65780370	65780370	+	Missense_Mutation	SNP	G	G	T			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr11:65780370G>T	uc001ogr.2	+	2	368	c.314G>T	c.(313-315)GGA>GTA	p.G105V	CST6_uc001ogs.1_Missense_Mutation_p.G15V	NM_001323	NP_001314	Q15828	CYTM_HUMAN	cystatin M precursor	105					anatomical structure morphogenesis	extracellular region	cysteine-type endopeptidase inhibitor activity			ovary(1)	1						AGGGTCACTGGAGACCACGTC	0.657		NaN											1	0	1.5739e-10	0.028581	1.68244e-10	17	30									
ODZ4	26011	broad.mit.edu	37	11	78443573	78443573	+	Missense_Mutation	SNP	G	G	A			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr11:78443573G>A	uc001ozl.3	-	21	3389	c.2926C>T	c.(2926-2928)CGG>TGG	p.R976W		NM_001098816	NP_001092286	Q6N022	TEN4_HUMAN	odz, odd Oz/ten-m homolog 4	976	Extracellular (Potential).				signal transduction	integral to membrane				ovary(2)|pancreas(2)	4						AAAGGTGCCCGCTCGAACCGC	0.542		NaN											0	0	0	0.020292	0	15	9									
AQP5	362	broad.mit.edu	37	12	50355840	50355840	+	Missense_Mutation	SNP	G	G	A			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr12:50355840G>A	uc001rvo.2	+	1	562	c.40G>A	c.(40-42)GTG>ATG	p.V14M		NM_001651	NP_001642	P55064	AQP5_HUMAN	aquaporin 5	14	Helical; (Potential).				carbon dioxide transport|excretion|odontogenesis|pancreatic juice secretion	apical plasma membrane|integral to plasma membrane	protein binding|water channel activity				0						CCTCAAGGCCGTGTTCGCAGA	0.428		NaN											0	0	0	0.043863	0	19	40									
C12orf42	374470	broad.mit.edu	37	12	103696166	103696166	+	Missense_Mutation	SNP	G	G	A			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr12:103696166G>A	uc001tjt.2	-	6	891	c.803C>T	c.(802-804)GCG>GTG	p.A268V	C12orf42_uc001tjs.2_Intron|C12orf42_uc009zuf.1_Missense_Mutation_p.A268V|C12orf42_uc001tju.2_Missense_Mutation_p.A173V	NM_198521	NP_940923	Q96LP6	CL042_HUMAN	hypothetical protein LOC374470	268										ovary(1)|central_nervous_system(1)	2						ATTTCCGGACGCGCCCAGGAG	0.667		NaN											0	0	0	0.01441	0	49	79									
TMEM132D	121256	broad.mit.edu	37	12	129559351	129559351	+	Missense_Mutation	SNP	G	G	A			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr12:129559351G>A	uc009zyl.1	-	9	2697	c.2369C>T	c.(2368-2370)ACG>ATG	p.T790M	TMEM132D_uc001uia.2_Missense_Mutation_p.T328M	NM_133448	NP_597705	Q14C87	T132D_HUMAN	transmembrane protein 132D precursor	790	Extracellular (Potential).					integral to membrane				ovary(10)|pancreas(2)|upper_aerodigestive_tract(1)|skin(1)	14	all_neural(191;0.101)|Medulloblastoma(191;0.163)	all_epithelial(31;0.0934)|Breast(359;0.133)		OV - Ovarian serous cystadenocarcinoma(86;0.000288)|Epithelial(86;0.0116)|all cancers(50;0.0246)		GATGTTTGCCGTTCCAACAGC	0.483		NaN											0	0	0	0.017118	0	33	86									
LECT1	11061	broad.mit.edu	37	13	53313190	53313190	+	Silent	SNP	G	G	A			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr13:53313190G>A	uc001vhf.2	-	2	300	c.189C>T	c.(187-189)TAC>TAT	p.Y63Y	LECT1_uc001vhg.2_Silent_p.Y63Y|LECT1_uc001vhh.2_Silent_p.Y90Y	NM_007015	NP_008946	O75829	LECT1_HUMAN	leukocyte cell derived chemotaxin 1 isoform 1	63	Helical; (Potential).				cartilage development|proteoglycan metabolic process	endomembrane system|extracellular region|integral to membrane				ovary(2)	2		Lung NSC(96;0.00212)|Breast(56;0.00235)|Hepatocellular(98;0.065)|Prostate(109;0.0771)|all_neural(104;0.173)		GBM - Glioblastoma multiforme(99;3.38e-08)		CCTTCCAGAAGTAGAAGGCCC	0.652		NaN											0	0	0	0.038147	0	7	20									
TMCO3	55002	broad.mit.edu	37	13	114202741	114202741	+	Nonsense_Mutation	SNP	C	C	T			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr13:114202741C>T	uc001vtu.3	+	12	2255	c.1894C>T	c.(1894-1896)CGA>TGA	p.R632*		NM_017905	NP_060375	Q6UWJ1	TMCO3_HUMAN	transmembrane and coiled-coil domains 3	632						integral to membrane	solute:hydrogen antiporter activity				0	Lung NSC(43;0.0161)|all_neural(89;0.0337)|Hepatocellular(20;0.0877)|Medulloblastoma(90;0.163)|Lung SC(71;0.218)	all_cancers(25;0.0145)|all_epithelial(44;0.00286)|all_lung(25;0.0273)|Breast(118;0.0411)|Lung NSC(25;0.0983)	all cancers(43;0.0317)			GAGCCGGGCGCGAAGAGCGGG	0.652		NaN											0	0	0	0.01441	0	49	77									
POTEG	404785	broad.mit.edu	37	14	19563461	19563461	+	Silent	SNP	T	T	A			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr14:19563461T>A	uc001vuz.1	+	5	1027	c.975T>A	c.(973-975)CTT>CTA	p.L325L	POTEG_uc001vva.1_RNA|POTEG_uc010ahc.1_RNA|uc001vvb.2_RNA	NM_001005356	NP_001005356	Q6S5H5	POTEG_HUMAN	POTE ankyrin domain family, member G	325	ANK 5.									ovary(1)	1						GCCTTCTACTTGAGCAAAACA	0.358		NaN											0	0	0	0.023175	0	27	276									
SUPT16H	11198	broad.mit.edu	37	14	21829276	21829276	+	Silent	SNP	T	T	C			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr14:21829276T>C	uc001wao.2	-	16	2229	c.1890A>G	c.(1888-1890)AAA>AAG	p.K630K	SUPT16H_uc001wan.2_5'Flank	NM_007192	NP_009123	Q9Y5B9	SP16H_HUMAN	chromatin-specific transcription elongation	630					DNA repair|DNA replication|nucleosome disassembly|positive regulation of transcription elongation, DNA-dependent|positive regulation of viral transcription|transcription elongation from RNA polymerase II promoter|viral reproduction	chromosome|nucleoplasm	GTP binding				0	all_cancers(95;0.00115)		Epithelial(56;1.62e-06)|all cancers(55;1.49e-05)	GBM - Glioblastoma multiforme(265;0.0159)		TTTTATAACGTTTCTGTACTT	0.408		NaN											0	0	0	0.008871	0	19	113									
EFS	10278	broad.mit.edu	37	14	23828664	23828664	+	Silent	SNP	T	T	G			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr14:23828664T>G	uc001wjo.2	-	4	1631	c.1023A>C	c.(1021-1023)CCA>CCC	p.P341P	EFS_uc001wjp.2_Silent_p.P248P|EFS_uc010tnm.1_Silent_p.P172P	NM_005864	NP_005855	O43281	EFS_HUMAN	embryonal Fyn-associated substrate isoform 1	341	SH3-binding (Potential).|Pro-rich.				cell adhesion|intracellular signal transduction	cytoplasm	SH3 domain binding			large_intestine(1)	1	all_cancers(95;7.12e-06)			GBM - Glioblastoma multiforme(265;0.00649)		GCAGGCGGGGTGGGGGTGGGG	0.697		NaN											0	0	0	0.010504	0	14	63									
NEO1	4756	broad.mit.edu	37	15	73593703	73593703	+	Missense_Mutation	SNP	G	G	A			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr15:73593703G>A	uc002avm.3	+	28	4349	c.4207G>A	c.(4207-4209)GGG>AGG	p.G1403R	NEO1_uc010ukx.1_Missense_Mutation_p.G1392R|NEO1_uc010uky.1_Missense_Mutation_p.G1350R|NEO1_uc010ukz.1_Missense_Mutation_p.G816R|NEO1_uc002avn.3_Missense_Mutation_p.G1041R	NM_002499	NP_002490	Q92859	NEO1_HUMAN	neogenin homolog 1 precursor	1403	Cytoplasmic (Potential).				axon guidance|cell adhesion|positive regulation of muscle cell differentiation	Golgi apparatus|integral to plasma membrane|nucleus				pancreas(1)	1						AGCCTCCATCGGGACTCTAGG	0.557		NaN											0	0	0	0.004672	0	3	36									
ZNF710	374655	broad.mit.edu	37	15	90611415	90611415	+	Missense_Mutation	SNP	G	G	A			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr15:90611415G>A	uc002bov.1	+	2	1169	c.1046G>A	c.(1045-1047)CGG>CAG	p.R349Q		NM_198526	NP_940928	Q8N1W2	ZN710_HUMAN	zinc finger protein 710	349					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			central_nervous_system(1)	1	Melanoma(11;0.00551)|Lung NSC(78;0.0196)|all_lung(78;0.04)		BRCA - Breast invasive adenocarcinoma(143;0.00769)|KIRC - Kidney renal clear cell carcinoma(17;0.0286)|Kidney(142;0.0514)|STAD - Stomach adenocarcinoma(125;0.129)			CAGGGCACCCGGCCCCACAAG	0.642		NaN											0	0	0	0.01441	0	71	35									
RNPS1	10921	broad.mit.edu	37	16	2304013	2304013	+	Silent	SNP	C	C	T			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr16:2304013C>T	uc002cpt.2	-	8	1416	c.870G>A	c.(868-870)CCG>CCA	p.P290P	DCI_uc002cpr.2_5'Flank|DCI_uc002cps.2_5'Flank|RNPS1_uc002cpu.2_Silent_p.P290P|RNPS1_uc002cpv.2_Silent_p.P113P|RNPS1_uc002cpw.2_Silent_p.P290P|RNPS1_uc002cpx.2_Silent_p.P267P|RNPS1_uc010uwa.1_RNA	NM_080594	NP_542161	Q15287	RNPS1_HUMAN	RNA-binding protein S1, serine-rich domain	290	Necessary for interaction with TRA2B, nuclear localization and exon-skipping.|Arg/Pro-rich.				mRNA 3'-end processing|mRNA export from nucleus|nuclear mRNA splicing, via spliceosome|nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|termination of RNA polymerase II transcription	cytosol|nuclear speck	mRNA 3'-UTR binding|nucleotide binding|protein binding			ovary(1)	1						GGCGGCGGCCCGGGGACCGTG	0.657		NaN											0	0	0	0.014758	0	4	8									
CIITA	4261	broad.mit.edu	37	16	11001758	11001758	+	Silent	SNP	G	G	A			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr16:11001758G>A	uc002dai.3	+	11	2542	c.2409G>A	c.(2407-2409)GCG>GCA	p.A803A	CIITA_uc002daj.3_Silent_p.A804A|CIITA_uc002dak.3_Intron|CIITA_uc002dag.2_Silent_p.A803A|CIITA_uc002dah.2_Silent_p.A755A|CIITA_uc010bup.1_Intron	NM_000246	NP_000237	P33076	C2TA_HUMAN	class II transactivator	803					interferon-gamma-mediated signaling pathway|negative regulation of transcription from RNA polymerase II promoter|positive regulation of MHC class I biosynthetic process|positive regulation of transcription from RNA polymerase II promoter|response to antibiotic|transcription, DNA-dependent	nucleus	activating transcription factor binding|ATP binding|protein C-terminus binding|protein complex binding|transcription coactivator activity|transcription regulatory region DNA binding			central_nervous_system(1)	1						CACTGCGGGCGCGGCAGCTGC	0.682		NaN	T	FLJ27352|CD274|CD273|RALGDS|RUNDC2A|C16orf75	PMBL|Hodgkin Lymphona|								0	0	0	0.045705	0	34	24									
ABCC1	4363	broad.mit.edu	37	16	16230365	16230365	+	Missense_Mutation	SNP	A	A	G			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr16:16230365A>G	uc010bvi.2	+	29	4331	c.4156A>G	c.(4156-4158)ATG>GTG	p.M1386V	ABCC1_uc010bvj.2_Missense_Mutation_p.M1327V|ABCC1_uc010bvk.2_Missense_Mutation_p.M1330V|ABCC1_uc010bvl.2_Missense_Mutation_p.M1386V|ABCC1_uc010bvm.2_Missense_Mutation_p.M1271V|ABCC1_uc002del.3_Missense_Mutation_p.M1280V	NM_004996	NP_004987	P33527	MRP1_HUMAN	ATP-binding cassette, sub-family C, member 1	1386	ABC transporter 2.|Cytoplasmic.				hormone biosynthetic process|leukotriene biosynthetic process|prostanoid metabolic process|response to drug	Golgi apparatus|integral to plasma membrane|membrane fraction|nucleus	ATP binding|ATPase activity, coupled to transmembrane movement of substances			ovary(4)	4					Daunorubicin(DB00694)|Glibenclamide(DB01016)|Probenecid(DB01032)|Saquinavir(DB01232)|Sulfinpyrazone(DB01138)	TTCCCTCCGAATGAACCTGGA	0.552		NaN											0	0	0	0.013537	0	10	25									
SLC5A11	115584	broad.mit.edu	37	16	24902200	24902200	+	Silent	SNP	G	G	A			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr16:24902200G>A	uc002dmu.2	+	9	907	c.675G>A	c.(673-675)GCG>GCA	p.A225A	SLC5A11_uc002dms.2_Silent_p.A161A|SLC5A11_uc010vcd.1_Silent_p.A190A|SLC5A11_uc002dmt.2_Intron|SLC5A11_uc010vce.1_Silent_p.A155A|SLC5A11_uc010bxt.2_Silent_p.A161A	NM_052944	NP_443176	Q8WWX8	SC5AB_HUMAN	solute carrier family 5 (sodium/glucose	225	Helical; (Potential).				apoptosis|carbohydrate transport|sodium ion transport	integral to membrane|plasma membrane	polyol transmembrane transporter activity|symporter activity			ovary(2)	2				GBM - Glioblastoma multiforme(48;0.0365)		GTTTTGCCGCGGTTGGTGGGA	0.542		NaN											0	0	0	0.01441	0	98	159									
MVP	9961	broad.mit.edu	37	16	29852959	29852959	+	Missense_Mutation	SNP	G	G	A			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr16:29852959G>A	uc002dui.2	+	9	1318	c.1234G>A	c.(1234-1236)GAA>AAA	p.E412K	uc002dtf.2_Intron|BOLA2_uc010bzb.1_Intron|MVP_uc010vdz.1_RNA|MVP_uc002duj.2_Missense_Mutation_p.E412K|MVP_uc010vea.1_Missense_Mutation_p.E6K	NM_005115	NP_005106	Q14764	MVP_HUMAN	major vault protein	412	MVP 8.				mRNA transport|protein transport|response to drug|transmembrane transport	cytoplasm|nuclear pore|ribonucleoprotein complex	protein binding			skin(2)|ovary(1)|central_nervous_system(1)	4						GACCCAGGACGAAGTCCTGTG	0.617		NaN											0	0	0	0.043863	0	20	18									
DOC2A	8448	broad.mit.edu	37	16	30017613	30017613	+	Missense_Mutation	SNP	C	C	A			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr16:30017613C>A	uc002dvm.2	-	11	1197	c.1097G>T	c.(1096-1098)CGG>CTG	p.R366L	uc002dtf.2_Intron|BOLA2_uc010bzb.1_Intron|DOC2A_uc002dvl.2_Missense_Mutation_p.R364L|DOC2A_uc002dvn.2_Missense_Mutation_p.R366L|DOC2A_uc010vef.1_RNA|DOC2A_uc002dvo.2_Missense_Mutation_p.R366L|DOC2A_uc002dvp.2_Missense_Mutation_p.R366L|DOC2A_uc002dvq.2_Missense_Mutation_p.R366L	NM_003586	NP_003577	Q14183	DOC2A_HUMAN	double C2-like domains, alpha	366	Interaction with UNC13D.				nervous system development|regulation of calcium ion-dependent exocytosis	cell junction|lysosome|synaptic vesicle membrane|synaptosome	calcium-dependent phospholipid binding|protein binding|transporter activity			ovary(2)	2						CCAGTGCTTCCGAGCCTCGCC	0.721		NaN											1	0	3.32936e-07	0.038395	3.47899e-07	19	23									
ITGAD	3681	broad.mit.edu	37	16	31425842	31425842	+	Silent	SNP	C	C	T			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr16:31425842C>T	uc002ebv.1	+	17	2116	c.2067C>T	c.(2065-2067)TTC>TTT	p.F689F	ITGAD_uc010cap.1_Silent_p.F690F	NM_005353	NP_005344	Q13349	ITAD_HUMAN	integrin, alpha D precursor	689	Extracellular (Potential).				cell-cell adhesion|cell-matrix adhesion|immune response|integrin-mediated signaling pathway	integrin complex	receptor activity			skin(1)	1						GTGCCATTTTCAATGAAACCA	0.493		NaN											0	0	0	0.01441	0	171	296									
YWHAE	7531	broad.mit.edu	37	17	1268269	1268270	+	Nonsense_Mutation	DNP	TA	TA	AT			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr17:1268269_1268270TA>AT	uc002fsj.2	-	2	299_300	c.147_148TA>AT	c.(145-150)TATAAG>TAATAG	p.49_50YK>**	YWHAE_uc002fsk.2_Nonsense_Mutation_p.27_28YK>**|YWHAE_uc010vqh.1_RNA|YWHAE_uc010vqi.1_RNA	NM_006761	NP_006752	P62258	1433E_HUMAN	tyrosine 3/tryptophan 5 -monooxygenase	49_50					apoptosis|G2/M transition of mitotic cell cycle|induction of apoptosis by extracellular signals|interspecies interaction between organisms|intracellular signal transduction|nerve growth factor receptor signaling pathway	cytosol|melanosome	histone deacetylase binding|phosphoserine binding	p.Y49C(1)		lung(2)|ovary(1)	3			OV - Ovarian serous cystadenocarcinoma(18;0.203)	UCEC - Uterine corpus endometrioid carcinoma (25;0.0887)		ATCACATTCTTATATGCAACAG	0.411		NaN											0	0	0	0.004672	0	10	153									
ADAM11	4185	broad.mit.edu	37	17	42854950	42854950	+	Missense_Mutation	SNP	G	G	A			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr17:42854950G>A	uc002ihh.2	+	22	1882	c.1882G>A	c.(1882-1884)GGC>AGC	p.G628S	ADAM11_uc010wjd.1_Missense_Mutation_p.G428S|ADAM11_uc002ihi.2_5'UTR	NM_002390	NP_002381	O75078	ADA11_HUMAN	ADAM metallopeptidase domain 11 preproprotein	628	Cys-rich.|Extracellular (Potential).				integrin-mediated signaling pathway|proteolysis	integral to membrane|plasma membrane	integrin binding|metalloendopeptidase activity|zinc ion binding			pancreas(1)	1		Prostate(33;0.0959)				CTACCACCAGGGCAAGGAGCT	0.617		NaN											0	0	0	0.01441	0	57	116									
CACNA1A	773	broad.mit.edu	37	19	13409700	13409700	+	Nonsense_Mutation	SNP	C	C	T			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr19:13409700C>T	uc010dze.2	-	19	2986	c.2750G>A	c.(2749-2751)TGG>TAG	p.W917*	CACNA1A_uc010dzc.2_Nonsense_Mutation_p.W442*|CACNA1A_uc002mwy.3_Nonsense_Mutation_p.W916*|CACNA1A_uc010xne.1_Nonsense_Mutation_p.W445*	NM_001127221	NP_001120693	O00555	CAC1A_HUMAN	calcium channel, alpha 1A subunit isoform 3	917	Cytoplasmic (Potential).				cell death|elevation of cytosolic calcium ion concentration|energy reserve metabolic process|membrane depolarization|regulation of insulin secretion	cytoplasm|nucleus	syntaxin binding			large_intestine(2)	2			OV - Ovarian serous cystadenocarcinoma(19;5.07e-21)		Bepridil(DB01244)|Cinnarizine(DB00568)|Loperamide(DB00836)|Nisoldipine(DB00401)|Pregabalin(DB00230)	CTCGCCCTCCCAGAACCCGGG	0.771		NaN											0	0	0	0.043863	0	17	22									
NWD1	284434	broad.mit.edu	37	19	16860863	16860863	+	Silent	SNP	G	G	A			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr19:16860863G>A	uc002neu.3	+	6	1832	c.1410G>A	c.(1408-1410)TCG>TCA	p.S470S	NWD1_uc002net.3_Silent_p.S335S|NWD1_uc002nev.3_Silent_p.S264S			Q149M9	NWD1_HUMAN	RecName: Full=NACHT and WD repeat domain-containing protein 1;	470	NACHT.						ATP binding			skin(3)|ovary(2)|pancreas(2)	7						CAGCTTGCTCGGGGGCACTGG	0.632		NaN											0	0	0	0.01441	0	51	105									
GMIP	51291	broad.mit.edu	37	19	19745888	19745888	+	Silent	SNP	G	G	A			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr19:19745888G>A	uc002nnd.2	-	16	1812	c.1695C>T	c.(1693-1695)CCC>CCT	p.P565P	GMIP_uc010xrb.1_Silent_p.P539P|GMIP_uc010xrc.1_Silent_p.P536P	NM_016573	NP_057657	Q9P107	GMIP_HUMAN	GEM interacting protein	565	Rho-GAP.				negative regulation of Rho GTPase activity|small GTPase mediated signal transduction	cytosol	metal ion binding|protein binding|Rho GTPase activator activity			ovary(1)	1						TGACCACAAAGGGTACCTCCT	0.597		NaN											0	0	0	0.017118	0	37	80									
RHPN2	85415	broad.mit.edu	37	19	33517486	33517486	+	Missense_Mutation	SNP	C	C	T			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr19:33517486C>T	uc002nuf.2	-	3	304	c.238G>A	c.(238-240)GTC>ATC	p.V80I	RHPN2_uc010xro.1_5'UTR|RHPN2_uc002nue.2_5'UTR	NM_033103	NP_149094	Q8IUC4	RHPN2_HUMAN	rhophilin, Rho GTPase binding protein 2	80	REM.				signal transduction	perinuclear region of cytoplasm	protein binding			central_nervous_system(5)|ovary(1)	6	Esophageal squamous(110;0.137)					TCTGAGTTGACGAAGCTCAGC	0.562		NaN											0	0	0	0.01441	0	62	89									
RYR1	6261	broad.mit.edu	37	19	39026668	39026668	+	Missense_Mutation	SNP	A	A	C			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr19:39026668A>C	uc002oit.2	+	82	11678	c.11548A>C	c.(11548-11550)AAC>CAC	p.N3850H	RYR1_uc002oiu.2_Missense_Mutation_p.N3845H|RYR1_uc002oiv.1_Missense_Mutation_p.N765H	NM_000540	NP_000531	P21817	RYR1_HUMAN	skeletal muscle ryanodine receptor isoform 1	3850					muscle contraction|release of sequestered calcium ion into cytosol|response to caffeine|response to hypoxia	cell cortex|cytosol|I band|integral to plasma membrane|junctional sarcoplasmic reticulum membrane|smooth endoplasmic reticulum|terminal cisterna	calcium ion binding|calmodulin binding|receptor activity|ryanodine-sensitive calcium-release channel activity			ovary(7)|pancreas(2)|breast(1)|central_nervous_system(1)|skin(1)	12	all_cancers(60;7.91e-06)		Lung(45;0.00172)|LUSC - Lung squamous cell carcinoma(53;0.00272)		Dantrolene(DB01219)	TGAGAGACAGAACAAGGCCGA	0.577		NaN											0	0	0	0.004482	0	8	15									
MYBPC2	4606	broad.mit.edu	37	19	50939408	50939408	+	Silent	SNP	C	C	T			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr19:50939408C>T	uc002psf.2	+	4	387	c.336C>T	c.(334-336)TCC>TCT	p.S112S		NM_004533	NP_004524	Q14324	MYPC2_HUMAN	myosin binding protein C, fast type	112	Ig-like C2-type 1.				cell adhesion|muscle filament sliding	cytosol|myosin filament	actin binding|structural constituent of muscle			breast(1)	1		all_neural(266;0.057)		OV - Ovarian serous cystadenocarcinoma(262;0.0079)|GBM - Glioblastoma multiforme(134;0.0144)		CCCACAACTCCGCCAGCAATG	0.607		NaN											0	0	0	0.009096	0	3	10									
EPN1	29924	broad.mit.edu	37	19	56200276	56200276	+	Silent	SNP	G	G	A			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr19:56200276G>A	uc002qlw.2	+	4	861	c.519G>A	c.(517-519)GCG>GCA	p.A173A	EPN1_uc002qlv.2_Silent_p.A173A|EPN1_uc010etd.2_Silent_p.A173A|EPN1_uc002qlx.2_Silent_p.A284A	NM_001130072	NP_001123544	Q9Y6I3	EPN1_HUMAN	epsin 1 isoform b	173					endocytosis|epidermal growth factor receptor signaling pathway|negative regulation of epidermal growth factor receptor signaling pathway	coated pit|cytoplasm|nucleus|plasma membrane	lipid binding				0		Colorectal(82;0.00244)|Ovarian(87;0.133)		GBM - Glioblastoma multiforme(193;0.112)		CTCCCGAGGCGGAGCAGGCGT	0.692		NaN											0	0	0	0.021553	0	5	6									
TTC27	55622	broad.mit.edu	37	2	33007733	33007733	+	Missense_Mutation	SNP	G	G	T			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr2:33007733G>T	uc002rom.2	+	15	2051	c.1820G>T	c.(1819-1821)CGA>CTA	p.R607L	TTC27_uc010ymx.1_Missense_Mutation_p.R557L|TTC27_uc002ron.2_RNA	NM_017735	NP_060205	Q6P3X3	TTC27_HUMAN	tetratricopeptide repeat domain 27	607	TPR 5.|HAT 2.						protein binding			central_nervous_system(1)	1						TCCTATATCCGATTAAAACAA	0.294		NaN											1	0	5.35267e-07	0.043863	5.53109e-07	17	20									
SOS1	6654	broad.mit.edu	37	2	39250333	39250333	+	Missense_Mutation	SNP	C	C	T			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr2:39250333C>T	uc002rrk.3	-	10	1277	c.1236G>A	c.(1234-1236)ATG>ATA	p.M412I	SOS1_uc010ynr.1_RNA|SOS1_uc002rrj.3_Missense_Mutation_p.M26I|SOS1_uc002rrl.2_Missense_Mutation_p.M144I	NM_005633	NP_005624	Q07889	SOS1_HUMAN	son of sevenless homolog 1	412					apoptosis|axon guidance|blood coagulation|epidermal growth factor receptor signaling pathway|fibroblast growth factor receptor signaling pathway|induction of apoptosis by extracellular signals|insulin receptor signaling pathway|leukocyte migration|nerve growth factor receptor signaling pathway|Ras protein signal transduction	cytosol	DNA binding|protein binding|Rho GTPase activator activity|Rho guanyl-nucleotide exchange factor activity			ovary(4)|breast(3)|lung(2)|central_nervous_system(1)	10		all_hematologic(82;0.21)				GTTTCCCCTTCATTTGCTGAC	0.353		NaN							Noonan_syndrome				0	0	0	0.041601	0	31	49									
ANKRD36B	57730	broad.mit.edu	37	2	98177186	98177186	+	Missense_Mutation	SNP	G	G	C			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr2:98177186G>C	uc010yvc.1	-	8	1087	c.807C>G	c.(805-807)GAC>GAG	p.D269E	ANKRD36B_uc010yve.1_RNA|ANKRD36B_uc010fif.2_RNA	NM_025190	NP_079466	Q8N2N9	AN36B_HUMAN	ankyrin repeat domain 36B	269											0						CAGAATCTTTGTCGTCACTTG	0.323		NaN											0	0	0	0.037714	0	27	41									
NFE2L2	4780	broad.mit.edu	37	2	178098810	178098810	+	Missense_Mutation	SNP	C	C	T			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08			C	T	C	C		Valid	Somatic	Phase_I	WXS	Fluidigm			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr2:178098810C>T	uc002ulh.3	-	2	790	c.235G>A	c.(235-237)GAG>AAG	p.E79K	NFE2L2_uc002ulg.3_Missense_Mutation_p.E63K|NFE2L2_uc010zfa.1_Missense_Mutation_p.E63K|NFE2L2_uc002uli.3_Missense_Mutation_p.E63K|NFE2L2_uc010fra.2_Missense_Mutation_p.E63K|NFE2L2_uc010frb.2_Missense_Mutation_p.E63K	NM_006164	NP_006155	Q16236	NF2L2_HUMAN	nuclear factor erythroid 2-like 2 isoform 1	79					transcription from RNA polymerase II promoter	centrosome|cytosol|nucleus|plasma membrane	protein dimerization activity|protein domain specific binding|sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity			central_nervous_system(1)	1			Epithelial(96;0.00442)|OV - Ovarian serous cystadenocarcinoma(117;0.00739)|all cancers(119;0.0195)|LUSC - Lung squamous cell carcinoma(2;0.036)|Lung(16;0.0935)			TCACCTGTCTCTTCATCTAGT	0.443		NaN	Mis		NSCLC|HNSCC					HNSCC(56;0.16)			0	0	0	0.030466	0	41	40									
ALS2CR12	130540	broad.mit.edu	37	2	202216040	202216040	+	Missense_Mutation	SNP	G	G	A	rs143899839		TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr2:202216040G>A	uc010ftg.2	-	2	532	c.88C>T	c.(88-90)CGC>TGC	p.R30C	ALS2CR12_uc002uya.3_Missense_Mutation_p.R30C|ALS2CR12_uc010fth.2_RNA	NM_139163	NP_631902	Q96Q35	AL2SB_HUMAN	amyotrophic lateral sclerosis 2 (juvenile)	30					regulation of GTPase activity		protein binding			ovary(1)|breast(1)|central_nervous_system(1)	3						GAGTTCTTGCGTGGTAGTTGA	0.517		NaN											0	0	0	0.016723	0	11	36									
SGK2	10110	broad.mit.edu	37	20	42204997	42204997	+	Missense_Mutation	SNP	G	G	A			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr20:42204997G>A	uc002xkv.2	+	10	1226	c.1007G>A	c.(1006-1008)CGG>CAG	p.R336Q	SGK2_uc002xkt.2_RNA|SGK2_uc002xkr.2_Missense_Mutation_p.R276Q|SGK2_uc010ggm.2_Missense_Mutation_p.R276Q|SGK2_uc002xks.2_Missense_Mutation_p.R275Q|SGK2_uc002xku.2_Missense_Mutation_p.R276Q	NM_016276	NP_057360	Q9HBY8	SGK2_HUMAN	serum/glucocorticoid regulated kinase 2 isoform	336	Protein kinase.				intracellular protein kinase cascade|response to oxidative stress		ATP binding|potassium channel regulator activity|protein serine/threonine kinase activity|sodium channel regulator activity			lung(3)|upper_aerodigestive_tract(1)|breast(1)|central_nervous_system(1)	6		Myeloproliferative disorder(115;0.00452)	COAD - Colon adenocarcinoma(18;0.0031)			CAGAGGCAGCGGCTGGGCTCC	0.602		NaN											0	0	0	0.017118	0	36	62									
PRIC285	85441	broad.mit.edu	37	20	62200824	62200824	+	Silent	SNP	G	G	A	rs143216041		TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr20:62200824G>A	uc002yfm.2	-	5	1657	c.765C>T	c.(763-765)TTC>TTT	p.F255F	PRIC285_uc002yfl.1_5'Flank	NM_001037335	NP_001032412	Q9BYK8	PR285_HUMAN	PPAR-alpha interacting complex protein 285	255					cellular lipid metabolic process|regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleoplasm	ATP binding|DNA binding|helicase activity|ribonuclease activity|RNA binding|transcription coactivator activity|zinc ion binding			central_nervous_system(2)	2	all_cancers(38;2.51e-11)|all_epithelial(29;8.27e-13)		Epithelial(9;1.27e-08)|all cancers(9;7.32e-08)|BRCA - Breast invasive adenocarcinoma(10;5.15e-06)			GGCCAAAGTCGAAGACCACCC	0.677		NaN											0	0	0	0.016522	0	22	30									
ARFRP1	10139	broad.mit.edu	37	20	62338384	62338384	+	Silent	SNP	G	G	A			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr20:62338384G>A	uc002yga.2	-	1	627	c.60C>T	c.(58-60)ATC>ATT	p.I20I	ARFRP1_uc002ygc.2_Silent_p.I20I|ARFRP1_uc002ygh.3_Silent_p.I20I|ARFRP1_uc011abf.1_Silent_p.I20I|ARFRP1_uc011abg.1_Silent_p.I20I|ARFRP1_uc002yge.2_RNA|ARFRP1_uc002ygd.2_RNA|ARFRP1_uc002ygf.2_Silent_p.I20I|ARFRP1_uc002ygg.2_RNA|ARFRP1_uc011abh.1_RNA|ZGPAT_uc002ygi.2_5'Flank|ZGPAT_uc002ygj.2_5'Flank|ZGPAT_uc002ygk.2_5'Flank|ZGPAT_uc010gkk.1_5'Flank|ZGPAT_uc010gkl.1_5'Flank|ZGPAT_uc002ygm.2_5'Flank|ZGPAT_uc002ygn.3_5'Flank	NM_003224	NP_003215	Q13795	ARFRP_HUMAN	ADP-ribosylation factor related protein 1	20					small GTPase mediated signal transduction	Golgi apparatus|membrane fraction	GTP binding|GTPase activity			breast(1)|skin(1)	2	all_cancers(38;9.53e-13)|all_epithelial(29;2.64e-14)|Lung NSC(23;7e-10)|all_lung(23;2.53e-09)		Epithelial(9;4.09e-08)|all cancers(9;1.7e-07)|OV - Ovarian serous cystadenocarcinoma(5;0.0102)			CCAGGATCAGGATGCAGTACT	0.607		NaN											0	0	0	0.030593	0	28	34									
BSN	8927	broad.mit.edu	37	3	49690722	49690722	+	Missense_Mutation	SNP	G	G	A	rs142148405		TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr3:49690722G>A	uc003cxe.3	+	5	3847	c.3733G>A	c.(3733-3735)GCA>ACA	p.A1245T		NM_003458	NP_003449	Q9UPA5	BSN_HUMAN	bassoon protein	1245					synaptic transmission	cell junction|cytoplasm|cytoskeleton|nucleus|synaptosome	metal ion binding			ovary(5)|pancreas(1)|central_nervous_system(1)|skin(1)	8				BRCA - Breast invasive adenocarcinoma(193;6.66e-05)|KIRC - Kidney renal clear cell carcinoma(197;0.0032)|Kidney(197;0.00336)		TCAGCCTGCCGCAGAGGGCAC	0.637		NaN											0	0	0	0.030466	0	41	67									
ARHGEF3	50650	broad.mit.edu	37	3	56807790	56807790	+	Missense_Mutation	SNP	G	G	C			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr3:56807790G>C	uc003dig.2	-	2	320	c.151C>G	c.(151-153)CTC>GTC	p.L51V	ARHGEF3_uc011bew.1_Missense_Mutation_p.L51V|ARHGEF3_uc003dih.2_Missense_Mutation_p.L83V|ARHGEF3_uc011bev.1_Missense_Mutation_p.L22V|ARHGEF3_uc003dif.2_Missense_Mutation_p.L57V|ARHGEF3_uc010hmy.1_5'UTR|ARHGEF3_uc003dii.2_Missense_Mutation_p.L51V	NM_019555	NP_062455	Q9NR81	ARHG3_HUMAN	Rho guanine nucleotide exchange factor 3 isoform	51					apoptosis|induction of apoptosis by extracellular signals|nerve growth factor receptor signaling pathway|regulation of Rho protein signal transduction|Rho protein signal transduction	cytosol	Rho guanyl-nucleotide exchange factor activity			ovary(1)	1				KIRC - Kidney renal clear cell carcinoma(284;0.0161)|Kidney(284;0.019)|OV - Ovarian serous cystadenocarcinoma(275;0.193)		GGCGGGATGAGGTTTGCTAGC	0.473		NaN											0	0	0	0.013726	0	28	10									
PRR23B	389151	broad.mit.edu	37	3	138738758	138738758	+	Missense_Mutation	SNP	G	G	A			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr3:138738758G>A	uc003esy.1	-	1	1011	c.746C>T	c.(745-747)CCG>CTG	p.P249L		NM_001013650	NP_001013672	Q6ZRT6	PR23B_HUMAN	proline rich 23B	249	Pro-rich.									breast(1)	1						TTCCGGGAGCGGCGAGCGCGC	0.672		NaN											0	0	0	0.009096	0	4	83									
PCOLCE2	26577	broad.mit.edu	37	3	142567124	142567124	+	Missense_Mutation	SNP	G	G	A			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr3:142567124G>A	uc003evd.2	-	3	579	c.383C>T	c.(382-384)TCT>TTT	p.S128F		NM_013363	NP_037495	Q9UKZ9	PCOC2_HUMAN	procollagen C-endopeptidase enhancer 2	128	CUB 1.					extracellular region	collagen binding|heparin binding|peptidase activator activity			ovary(2)|skin(1)	3						GTTGGCATCAGAAATCATCTG	0.512		NaN											0	0	0	0.021022	0	39	61									
SKIL	6498	broad.mit.edu	37	3	170099114	170099114	+	Nonsense_Mutation	SNP	C	C	G	rs140174204	by1000genomes	TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr3:170099114C>G	uc003fgu.2	+	3	1893	c.1181C>G	c.(1180-1182)TCA>TGA	p.S394*	SKIL_uc011bps.1_Nonsense_Mutation_p.S374*|SKIL_uc003fgv.2_Nonsense_Mutation_p.S394*|SKIL_uc003fgw.2_Nonsense_Mutation_p.S394*	NM_005414	NP_005405	P12757	SKIL_HUMAN	SKI-like isoform 1	394					cell cycle arrest|negative regulation of cell differentiation|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transforming growth factor beta receptor signaling pathway|positive regulation of axonogenesis|protein heterotrimerization|protein homotrimerization|regulation of apoptosis|regulation of apoptosis|response to antibiotic|response to growth factor stimulus|skeletal muscle tissue development	cytoplasm|PML body	chromatin binding|nucleotide binding|protein complex binding|protein domain specific binding|SMAD binding|transcription corepressor activity|transcription repressor activity			ovary(2)|skin(1)	3	all_cancers(22;7.13e-23)|all_epithelial(15;9.95e-28)|all_lung(20;1.23e-16)|Lung NSC(18;5.15e-16)|Ovarian(172;0.000337)|Breast(254;0.137)		Lung(28;2.71e-13)|STAD - Stomach adenocarcinoma(35;0.197)			CAGACACATTCATTTTTACAC	0.284		NaN											0	0	0	0.041601	0	33	56									
USP13	8975	broad.mit.edu	37	3	179462957	179462957	+	Missense_Mutation	SNP	T	T	C			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr3:179462957T>C	uc003fkh.2	+	13	1742	c.1661T>C	c.(1660-1662)GTT>GCT	p.V554A	USP13_uc003fkf.2_Intron	NM_003940	NP_003931	Q92995	UBP13_HUMAN	ubiquitin thiolesterase 13	554					ubiquitin-dependent protein catabolic process		cysteine-type endopeptidase activity|omega peptidase activity|protein binding|ubiquitin thiolesterase activity|ubiquitin-specific protease activity|zinc ion binding			ovary(1)	1	all_cancers(143;7.79e-15)|Ovarian(172;0.0338)|Breast(254;0.148)		OV - Ovarian serous cystadenocarcinoma(80;1e-25)|GBM - Glioblastoma multiforme(14;0.0169)			CCAGAAAATGTTGATGATTTC	0.512		NaN											0	0	0	0.041601	0	31	58									
TRIM2	23321	broad.mit.edu	37	4	154217081	154217081	+	Missense_Mutation	SNP	C	C	T			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr4:154217081C>T	uc003ing.2	+	6	1523	c.1322C>T	c.(1321-1323)CCG>CTG	p.P441L	TRIM2_uc003inh.2_Missense_Mutation_p.P468L	NM_001130067	NP_001123539	Q9C040	TRIM2_HUMAN	tripartite motif-containing 2 isoform 2	441						cytoplasm	zinc ion binding			central_nervous_system(1)	1	all_hematologic(180;0.093)	Medulloblastoma(177;0.00225)		GBM - Glioblastoma multiforme(119;0.0102)|LUSC - Lung squamous cell carcinoma(193;0.0703)		GTTAAGTCCCCGGGGAGCGGC	0.527		NaN											0	0	0	0.012213	0	33	41									
FAT1	2195	broad.mit.edu	37	4	187539564	187539564	+	Nonsense_Mutation	SNP	G	G	A			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr4:187539564G>A	uc003izf.2	-	10	8364	c.8176C>T	c.(8176-8178)CGA>TGA	p.R2726*		NM_005245	NP_005236	Q14517	FAT1_HUMAN	FAT tumor suppressor 1 precursor	2726	Extracellular (Potential).|Cadherin 25.				actin filament organization|anatomical structure morphogenesis|cell migration|cell-cell signaling|establishment or maintenance of cell polarity|homophilic cell adhesion	cell-cell junction|integral to plasma membrane|nucleus|perinuclear region of cytoplasm	calcium ion binding|protein binding			ovary(10)|central_nervous_system(1)|pancreas(1)	12						TGTTCTGCTCGGATGAGATCT	0.453		NaN								HNSCC(5;0.00058)			0	0	0	0.01441	0	56	101									
CDH10	1008	broad.mit.edu	37	5	24537588	24537588	+	Missense_Mutation	SNP	C	C	T			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr5:24537588C>T	uc003jgr.1	-	3	759	c.427G>A	c.(427-429)GAG>AAG	p.E143K	CDH10_uc011cnu.1_RNA	NM_006727	NP_006718	Q9Y6N8	CAD10_HUMAN	cadherin 10, type 2 preproprotein	143	Cadherin 1.|Extracellular (Potential).				adherens junction organization|cell junction assembly|homophilic cell adhesion	integral to membrane|plasma membrane	calcium ion binding			ovary(6)|pancreas(4)|breast(2)	12				STAD - Stomach adenocarcinoma(35;0.0556)		AACTCTGACTCTGGCTCTACT	0.423		NaN								HNSCC(23;0.051)			0	0	0	0.01441	0	62	109									
HTR1A	3350	broad.mit.edu	37	5	63257179	63257179	+	Missense_Mutation	SNP	G	G	A			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr5:63257179G>A	uc011cqt.1	-	1	368	c.368C>T	c.(367-369)TCC>TTC	p.S123F		NM_000524	NP_000515	P08908	5HT1A_HUMAN	5-hydroxytryptamine (serotonin) receptor 1A	123	Helical; Name=3; (By similarity).				behavior|positive regulation of cell proliferation	integral to plasma membrane	serotonin receptor activity			ovary(2)|pancreas(2)	4		Lung NSC(810;3.55e-06)|Prostate(74;0.0352)|Ovarian(174;0.0545)|Breast(144;0.0575)|Colorectal(97;0.234)		Lung(70;0.105)	Alprenolol(DB00866)|Aripiprazole(DB01238)|Buspirone(DB00490)|Clozapine(DB00363)|Eletriptan(DB00216)|Ergoloid mesylate(DB01049)|Fluvoxamine(DB00176)|Lisuride(DB00589)|Methysergide(DB00247)|Mirtazapine(DB00370)|Pindolol(DB00960)|Propranolol(DB00571)|Quetiapine(DB01224)|Sertraline(DB01104)|Tegaserod(DB01079)|Trazodone(DB00656)|Venlafaxine(DB00285)|Ziprasidone(DB00246)	GTGCAAGATGGATGAGGTGCA	0.642		NaN											0	0	0	0.01892	0	26	13									
LCA5	167691	broad.mit.edu	37	6	80197346	80197346	+	Missense_Mutation	SNP	G	G	A	rs139048294		TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr6:80197346G>A	uc003pix.2	-	8	1904	c.1469C>T	c.(1468-1470)CCA>CTA	p.P490L	LCA5_uc003piy.2_Missense_Mutation_p.P490L	NM_001122769	NP_001116241	Q86VQ0	LCA5_HUMAN	Leber congenital amaurosis 5	490					protein transport	cilium axoneme|microtubule basal body	protein binding				0		all_cancers(76;3.32e-05)|Acute lymphoblastic leukemia(125;1.1e-05)|all_hematologic(105;0.00117)|all_epithelial(107;0.0176)		BRCA - Breast invasive adenocarcinoma(397;0.0657)		AGGTAACAATGGCAAAACAGG	0.383		NaN											0	0	0	0.01441	0	66	108									
SSPO	23145	broad.mit.edu	37	7	149489805	149489805	+	Missense_Mutation	SNP	G	G	A			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr7:149489805G>A	uc010lpk.2	+	39	5861	c.5861G>A	c.(5860-5862)CGC>CAC	p.R1954H		NM_198455	NP_940857	A2VEC9	SSPO_HUMAN	SCO-spondin precursor	1954	TSP type-1 3.				cell adhesion	extracellular space	peptidase inhibitor activity				0	Melanoma(164;0.165)|Ovarian(565;0.177)		OV - Ovarian serous cystadenocarcinoma(82;0.00625)			GGCATCCACCGCAAGGCACGC	0.687		NaN											0	0	0	0.016723	0	13	15									
TNKS	8658	broad.mit.edu	37	8	9584174	9584174	+	Missense_Mutation	SNP	G	G	A			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr8:9584174G>A	uc003wss.2	+	13	1950	c.1945G>A	c.(1945-1947)GAT>AAT	p.D649N	TNKS_uc011kww.1_Missense_Mutation_p.D412N|TNKS_uc010lrs.1_RNA	NM_003747	NP_003738	O95271	TNKS1_HUMAN	tankyrase, TRF1-interacting ankyrin-related	649					mitotic spindle organization|mRNA transport|negative regulation of DNA binding|peptidyl-serine phosphorylation|peptidyl-threonine phosphorylation|positive regulation of canonical Wnt receptor signaling pathway|positive regulation of telomere maintenance via telomerase|protein auto-ADP-ribosylation|protein localization to chromosome, telomeric region|protein poly-ADP-ribosylation|protein polyubiquitination|protein transport|spindle assembly|transmembrane transport|Wnt receptor signaling pathway	chromosome, centromeric region|Golgi membrane|microsome|nuclear chromosome, telomeric region|nuclear membrane|nuclear pore|pericentriolar material	NAD+ ADP-ribosyltransferase activity|protein binding|zinc ion binding			lung(4)|ovary(2)|kidney(1)	7				COAD - Colon adenocarcinoma(149;0.0467)		ACGTACTTCTGATGTTGATTA	0.363		NaN											0	0	0	0.01441	0	70	119									
UNC5D	137970	broad.mit.edu	37	8	35608269	35608269	+	Missense_Mutation	SNP	A	A	G			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr8:35608269A>G	uc003xjr.1	+	13	2433	c.2105A>G	c.(2104-2106)AAC>AGC	p.N702S	UNC5D_uc003xjs.1_Missense_Mutation_p.N697S|UNC5D_uc003xju.1_Missense_Mutation_p.N278S	NM_080872	NP_543148	Q6UXZ4	UNC5D_HUMAN	unc-5 homolog D precursor	702	Cytoplasmic (Potential).				apoptosis|axon guidance	integral to membrane	receptor activity			upper_aerodigestive_tract(2)|ovary(2)|pancreas(1)|skin(1)	6				READ - Rectum adenocarcinoma(1;1.31e-05)|Colorectal(1;0.000723)		ATGTCCTGTAACTCCCTGGAT	0.463		NaN											0	0	0	0.01441	0	66	114									
PXDNL	137902	broad.mit.edu	37	8	52321370	52321370	+	Silent	SNP	T	T	C			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr8:52321370T>C	uc003xqu.3	-	17	2915	c.2814A>G	c.(2812-2814)ACA>ACG	p.T938T	PXDNL_uc003xqt.3_RNA	NM_144651	NP_653252	A1KZ92	PXDNL_HUMAN	peroxidasin homolog-like precursor	938					hydrogen peroxide catabolic process	extracellular space	heme binding|peroxidase activity			ovary(1)|pancreas(1)	2		all_cancers(86;0.107)|Lung NSC(129;0.00641)|all_epithelial(80;0.00716)|all_lung(136;0.015)				TGGGTGGGCCTGTAGAAAAGG	0.647		NaN											0	0	0	0.006214	0	9	39									
HAS2	3037	broad.mit.edu	37	8	122626355	122626355	+	Missense_Mutation	SNP	A	A	T			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr8:122626355A>T	uc003yph.2	-	4	2191	c.1653T>A	c.(1651-1653)GAT>GAA	p.D551E		NM_005328	NP_005319	Q92819	HAS2_HUMAN	hyaluronan synthase 2	551	Extracellular (Potential).					integral to plasma membrane	hyaluronan synthase activity		HAS2/PLAG1(10)	soft_tissue(10)|ovary(5)	15	Lung NSC(37;3.12e-08)|Ovarian(258;0.0254)|Hepatocellular(40;0.0997)|all_neural(195;0.142)		STAD - Stomach adenocarcinoma(47;0.00503)			AAGATCATACATCAAGCACCA	0.443		NaN											0	0	0	0.01441	0	52	135									
ATAD2	29028	broad.mit.edu	37	8	124382167	124382167	+	Missense_Mutation	SNP	A	A	T	rs149531312	byFrequency	TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr8:124382167A>T	uc003yqh.3	-	7	933	c.825T>A	c.(823-825)GAT>GAA	p.D275E	ATAD2_uc011lii.1_Missense_Mutation_p.D66E|ATAD2_uc003yqi.3_RNA|ATAD2_uc003yqj.2_Missense_Mutation_p.D275E	NM_014109	NP_054828	Q6PL18	ATAD2_HUMAN	ATPase family, AAA domain containing 2	275	Asp-rich.				regulation of transcription, DNA-dependent|transcription, DNA-dependent	mitochondrion|nucleus	ATP binding|ATPase activity			ovary(2)	2	Lung NSC(37;1.25e-09)|Ovarian(258;0.00838)		STAD - Stomach adenocarcinoma(47;0.00288)			cttcatcatcatcatcatcat	0.179		NaN											0	0	0	0.004482	0	9	31									
ATAD2	29028	broad.mit.edu	37	8	124382176	124382176	+	Silent	SNP	A	A	G	rs148244463		TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr8:124382176A>G	uc003yqh.3	-	7	924	c.816T>C	c.(814-816)GAT>GAC	p.D272D	ATAD2_uc011lii.1_Silent_p.D63D|ATAD2_uc003yqi.3_RNA|ATAD2_uc003yqj.2_Silent_p.D272D	NM_014109	NP_054828	Q6PL18	ATAD2_HUMAN	ATPase family, AAA domain containing 2	272	Asp-rich.				regulation of transcription, DNA-dependent|transcription, DNA-dependent	mitochondrion|nucleus	ATP binding|ATPase activity			ovary(2)	2	Lung NSC(37;1.25e-09)|Ovarian(258;0.00838)		STAD - Stomach adenocarcinoma(47;0.00288)			catcatcatcatcatcatcgt	0.164		NaN											0	0	0	0.004482	0	8	29									
ATAD2	29028	broad.mit.edu	37	8	124382194	124382194	+	Missense_Mutation	SNP	A	A	T	rs140021846	byFrequency	TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr8:124382194A>T	uc003yqh.3	-	7	906	c.798T>A	c.(796-798)GAT>GAA	p.D266E	ATAD2_uc011lii.1_Missense_Mutation_p.D57E|ATAD2_uc003yqi.3_RNA|ATAD2_uc003yqj.2_Missense_Mutation_p.D266E	NM_014109	NP_054828	Q6PL18	ATAD2_HUMAN	ATPase family, AAA domain containing 2	266	Asp-rich.				regulation of transcription, DNA-dependent|transcription, DNA-dependent	mitochondrion|nucleus	ATP binding|ATPase activity			ovary(2)	2	Lung NSC(37;1.25e-09)|Ovarian(258;0.00838)		STAD - Stomach adenocarcinoma(47;0.00288)			cgtcatcatcatcatcatctt	0.169		NaN											0	0	0	0.014758	0	4	42									
COL22A1	169044	broad.mit.edu	37	8	139606274	139606274	+	Missense_Mutation	SNP	G	G	A			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr8:139606274G>A	uc003yvd.2	-	63	5048	c.4601C>T	c.(4600-4602)CCC>CTC	p.P1534L	COL22A1_uc011ljo.1_Missense_Mutation_p.P814L	NM_152888	NP_690848	Q8NFW1	COMA1_HUMAN	collagen, type XXII, alpha 1	1534	Pro-rich.|Gly-rich.|Collagen-like 15.				cell adhesion	collagen|cytoplasm	structural molecule activity			ovary(11)|pancreas(1)|skin(1)	13	all_epithelial(106;1.55e-12)|Lung NSC(106;1.67e-05)|all_lung(105;3.39e-05)|Ovarian(258;0.00672)|Acute lymphoblastic leukemia(118;0.155)		BRCA - Breast invasive adenocarcinoma(115;0.0517)			GGGACCTATGGGTCCAGAGGG	0.652		NaN								HNSCC(7;0.00092)			0	0	0	0.019004	0	35	70									
NFIL3	4783	broad.mit.edu	37	9	94172665	94172665	+	Missense_Mutation	SNP	C	C	G			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr9:94172665C>G	uc004arh.2	-	2	747	c.352G>C	c.(352-354)GAG>CAG	p.E118Q		NM_005384	NP_005375	Q16649	NFIL3_HUMAN	nuclear factor, interleukin 3 regulated	118	Leucine-zipper.				circadian rhythm|immune response|transcription from RNA polymerase II promoter	nucleus	protein dimerization activity|sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity|transcription corepressor activity				0						GAAAGCAGCTCAGCTTTTAAA	0.393		NaN											0	0	0	0.01441	0	63	102									
SVEP1	79987	broad.mit.edu	37	9	113173859	113173859	+	Missense_Mutation	SNP	G	G	C			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr9:113173859G>C	uc010mtz.2	-	37	6469	c.6132C>G	c.(6130-6132)TTC>TTG	p.F2044L	SVEP1_uc010mty.2_5'UTR	NM_153366	NP_699197	Q4LDE5	SVEP1_HUMAN	polydom	2044	Sushi 11.				cell adhesion	cytoplasm|extracellular region|membrane	calcium ion binding			ovary(7)	7						AGCAGTAGTAGAATGCAATGT	0.557		NaN											0	0	0	0.024245	0	15	27									
ZMYM3	9203	broad.mit.edu	37	X	70471085	70471085	+	Nonsense_Mutation	SNP	C	C	A			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chrX:70471085C>A	uc004dzh.1	-	4	808	c.721G>T	c.(721-723)GAG>TAG	p.E241*	BCYRN1_uc011mpt.1_Intron|ZMYM3_uc004dzi.1_Nonsense_Mutation_p.E241*|ZMYM3_uc004dzj.1_Nonsense_Mutation_p.E241*|ZMYM3_uc011mpu.1_5'UTR|ZMYM3_uc004dzk.3_Nonsense_Mutation_p.E241*|ZMYM3_uc004dzl.3_Nonsense_Mutation_p.E241*|ZMYM3_uc004dzm.3_Nonsense_Mutation_p.E241*	NM_201599	NP_963893	Q14202	ZMYM3_HUMAN	zinc finger protein 261	241					multicellular organismal development	nucleus	DNA binding|zinc ion binding			ovary(1)	1	Renal(35;0.156)					CTAACGCGCTCGCTTCTCTTC	0.527		NaN											1	0	1.99505e-19	0.012213	2.18282e-19	32	8									
MAGT1	84061	broad.mit.edu	37	X	77112890	77112890	+	Silent	SNP	C	C	T			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chrX:77112890C>T	uc004fof.2	-	4	653	c.591G>A	c.(589-591)CAG>CAA	p.Q197Q	MAGT1_uc004fog.3_Intron	NM_032121	NP_115497	Q9H0U3	MAGT1_HUMAN	magnesium transporter 1	165					protein N-linked glycosylation via asparagine	integral to membrane|oligosaccharyltransferase complex				upper_aerodigestive_tract(1)	1						ACCGGGCAATCTGCTCAGCTG	0.463		NaN											0	0	0	0.01441	0	75	19									
DIAPH2	1730	broad.mit.edu	37	X	96354743	96354743	+	Missense_Mutation	SNP	G	G	C			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chrX:96354743G>C	uc004efu.3	+	20	2694	c.2298G>C	c.(2296-2298)GAG>GAC	p.E766D	DIAPH2_uc004eft.3_Missense_Mutation_p.E766D	NM_006729	NP_006720	O60879	DIAP2_HUMAN	diaphanous 2 isoform 156	766	FH2.				cell differentiation|cytokinesis|multicellular organismal development|oogenesis	cytosol|early endosome|Golgi apparatus|mitochondrion|nucleolus	receptor binding|Rho GTPase binding			ovary(3)|lung(1)	4						AATTAGCAGAGCTTAAGAATG	0.358		NaN											0	0	0	0.01892	0	22	4									
PAK3	5063	broad.mit.edu	37	X	110439847	110439847	+	Silent	SNP	C	C	T			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chrX:110439847C>T	uc004epa.2	+	13	1458	c.1431C>T	c.(1429-1431)TAC>TAT	p.Y477Y	PAK3_uc010npt.1_Silent_p.Y462Y|PAK3_uc010npu.1_Silent_p.Y462Y|PAK3_uc004eoy.1_Silent_p.Y217Y|PAK3_uc004eoz.2_Silent_p.Y462Y|PAK3_uc011mst.1_RNA|PAK3_uc010npv.1_Silent_p.Y498Y|PAK3_uc010npw.1_Silent_p.Y483Y	NM_001128173	NP_001121645	O75914	PAK3_HUMAN	p21-activated kinase 3 isoform d	477	Protein kinase.				multicellular organismal development		ATP binding|metal ion binding|protein serine/threonine kinase activity|SH3 domain binding			lung(6)|ovary(3)|large_intestine(1)	10						AACCCCCTTACCTTAATGAAA	0.438		NaN								TSP Lung(19;0.15)			0	0	0	0.014323	0	21	43									
MAGEA12	4111	broad.mit.edu	37	X	151900051	151900051	+	Missense_Mutation	SNP	C	C	G			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chrX:151900051C>G	uc010ntp.2	-	3	1104	c.750G>C	c.(748-750)TTG>TTC	p.L250F	MAGEA12_uc004fgb.2_Intron|MAGEA12_uc004fgc.2_Missense_Mutation_p.L250F	NM_005367	NP_005358	P43365	MAGAC_HUMAN	melanoma antigen family A, 12	250	MAGE.									skin(1)	1	Acute lymphoblastic leukemia(192;6.56e-05)					TTTCCTGCACCAAATCTTGGG	0.567		NaN											0	0	0	0.041601	0	32	104									
EPHA2	1969	broad.mit.edu	37	1	16477440	16477440	+	Frame_Shift_Del	DEL	G	G	-			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr1:16477440delG	uc001aya.1	-	2	241	c.104delC	c.(103-105)GCTfs	p.A35fs	EPHA2_uc010oca.1_Frame_Shift_Del_p.A35fs	NM_004431	NP_004422	P29317	EPHA2_HUMAN	ephrin receptor EphA2 precursor	35	Extracellular (Potential).				activation of Rac GTPase activity|angiogenesis|apoptosis|cell chemotaxis|negative regulation of protein kinase B signaling cascade|positive regulation of establishment of protein localization in plasma membrane|protein kinase B signaling cascade|regulation of blood vessel endothelial cell migration|regulation of cell adhesion mediated by integrin|regulation of lamellipodium assembly|response to growth factor stimulus	focal adhesion|integral to plasma membrane|lamellipodium membrane|ruffle membrane	ATP binding|ephrin receptor activity|protein binding			lung(3)|central_nervous_system(3)|stomach(2)|ovary(2)	10		Colorectal(325;3.46e-05)|Breast(348;0.000278)|Lung NSC(340;0.000419)|Renal(390;0.000518)|all_lung(284;0.000567)|Ovarian(437;0.0221)|Myeloproliferative disorder(586;0.0255)		UCEC - Uterine corpus endometrioid carcinoma (279;0.0181)|Colorectal(212;3.63e-07)|COAD - Colon adenocarcinoma(227;2.25e-05)|BRCA - Breast invasive adenocarcinoma(304;9.58e-05)|Kidney(64;0.000175)|KIRC - Kidney renal clear cell carcinoma(64;0.00261)|STAD - Stomach adenocarcinoma(313;0.00669)|READ - Rectum adenocarcinoma(331;0.0649)	Dasatinib(DB01254)	TCCAGCTGCAGCAAAGTCCAG	0.597		NaN											NaN	NaN	NaN	NaN	NaN	57	39	---	---							
MUC5B	727897	broad.mit.edu	37	11	1276413	1276414	+	Frame_Shift_Ins	INS	-	-	G			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr11:1276413_1276414insG	uc009ycr.1	+	58	16944_16945	c.16818_16819insG	c.(16816-16821)ACTGCCfs	p.T5606fs	MUC5B_uc001ltb.2_Frame_Shift_Ins_p.T5272fs	NM_017511	NP_059981	Q9HC84	MUC5B_HUMAN	SubName: Full=Mucin 5AC, oligomeric mucus/gel-forming;	5269_5270	VWFD 4.				cell adhesion	extracellular region	extracellular matrix structural constituent|protein binding				0		all_cancers(49;6.97e-08)|all_epithelial(84;3.45e-05)|Breast(177;0.000307)|Ovarian(85;0.000953)|Medulloblastoma(188;0.0109)|all_neural(188;0.0299)|Lung NSC(207;0.229)		BRCA - Breast invasive adenocarcinoma(625;0.00141)|Lung(200;0.0853)|LUSC - Lung squamous cell carcinoma(625;0.1)		CACCCCCCACTGCCAGCCCCGC	0.673		NaN											NaN	NaN	NaN	NaN	NaN	4	2	---	---							
MLL2	8085	broad.mit.edu	37	12	49420990	49421006	+	Frame_Shift_Del	DEL	GGGGAAGGGGGCGGGGA	GGGGAAGGGGGCGGGGA	-			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr12:49420990_49421006delGGGGAAGGGGGCGGGGA	uc001rta.3	-	48	14743_14759	c.14743_14759delTCCCCGCCCCCTTCCCC	c.(14743-14760)TCCCCGCCCCCTTCCCCCfs	p.S4915fs		NM_003482	NP_003473	O14686	MLL2_HUMAN	myeloid/lymphoid or mixed-lineage leukemia 2	4915_4920	Pro-rich.				chromatin silencing|histone H3-K4 methylation|oocyte growth|positive regulation of cell proliferation|positive regulation of estrogen receptor signaling pathway|positive regulation of transcription from RNA polymerase II promoter|response to estrogen stimulus|transcription, DNA-dependent	histone methyltransferase complex	histone-lysine N-methyltransferase activity|protein binding|transcription regulatory region DNA binding|zinc ion binding			kidney(16)|central_nervous_system(12)|lung(4)|skin(4)|ovary(3)|pancreas(2)	41						AGGTGCCAAGGGGGAAGGGGGCGGGGAGGGTTCTTCA	0.641		NaN	N|F|Mis		medulloblastoma|renal					HNSCC(34;0.089)			NaN	NaN	NaN	NaN	NaN	48	52	---	---							
PRR12	57479	broad.mit.edu	37	19	50117814	50117814	+	Frame_Shift_Del	DEL	C	C	-			TCGA-BT-A42B-01A-32D-A23M-08	TCGA-BT-A42B-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	316411ea-2e0b-494a-b3a9-ce8225140e32	791afb2c-5644-4d7e-8c0b-249c53d4e64a	g.chr19:50117814delC	uc002poo.3	+	7	4798	c.4798delC	c.(4798-4800)CCCfs	p.P1600fs		NM_020719	NP_065770	Q9ULL5	PRR12_HUMAN	proline rich 12	779							DNA binding			central_nervous_system(1)|pancreas(1)	2		all_lung(116;2.45e-07)|Lung NSC(112;1.24e-06)|Ovarian(192;0.0728)|all_neural(266;0.0887)		OV - Ovarian serous cystadenocarcinoma(262;0.00319)|GBM - Glioblastoma multiforme(134;0.0132)		GGGGCGTGAACCCCCACCCAT	0.612		NaN											NaN	NaN	NaN	NaN	NaN	2	4	---	---