Hugo_Symbol Entrez_Gene_Id Center NCBI_Build Chromosome Start_Position End_Position Strand Variant_Classification Variant_Type Reference_Allele Tumor_Seq_Allele1 Tumor_Seq_Allele2 dbSNP_RS dbSNP_Val_Status Tumor_Sample_Barcode Matched_Norm_Sample_Barcode Match_Norm_Seq_Allele1 Match_Norm_Seq_Allele2 Tumor_Validation_Allele1 Tumor_Validation_Allele2 Match_Norm_Validation_Allele1 Match_Norm_Validation_Allele2 Verification_Status Validation_Status Mutation_Status Sequencing_Phase Sequence_Source Validation_Method Score BAM_File Sequencer Tumor_Sample_UUID Matched_Norm_Sample_UUID chromosome_name_WU start_WU stop_WU reference_WU variant_WU type_WU gene_name_WU transcript_name_WU transcript_species_WU transcript_source_WU transcript_version_WU strand_WU transcript_status_WU trv_type_WU c_position_WU amino_acid_change_WU ucsc_cons_WU domain_WU all_domains_WU deletion_substructures_WU transcript_error_WU default_gene_name_WU gene_name_source_WU ensembl_gene_id normal_ref_reads normal_var_reads normal_vaf tumor_ref_reads tumors_var_reads tumor_vaf EVS_EA EVS_AA EVS_All ATF6B 0 genome.wustl.edu 37 6 32088603 32088603 + Silent SNP T T C TCGA-A8-A086-01A-11W-A019-09 TCGA-A8-A086-10A-01W-A021-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 13d89926-9e4c-434f-80b4-4fb15e4426f6 1af700be-a789-4f68-bd75-290aeed2fd7b 6 32088603 32088603 T C SNP ATF6B ENST00000375203 human ensembl 69_37n -1 known silent c.777 p.R259 0.824 NULL pfam_bZIP_1,pfam_bZIP_2,smart_bZIP,pfscan_bZIP - no_errors ATF6B HGNC ENSG00000213676 101 0 0.00 104 64 38.10 - - - CLCNKB 0 genome.wustl.edu 37 1 16373087 16373087 + Nonsense_Mutation SNP G G A TCGA-A8-A086-01A-11W-A019-09 TCGA-A8-A086-10A-01W-A021-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 13d89926-9e4c-434f-80b4-4fb15e4426f6 1af700be-a789-4f68-bd75-290aeed2fd7b 1 16373087 16373087 G A SNP CLCNKB ENST00000375679 human ensembl 69_37n +1 known nonsense c.287 p.W96* 1.000 superfamily_Cl-channel_core pfam_Cl-channel_volt-gated,pfam_Cysta_beta_synth_core,superfamily_Cl-channel_core,smart_Cysta_beta_synth_core,prints_Cl-channel_volt-gated,prints_Cl_channel-K - no_errors CLCNKB HGNC ENSG00000184908 23 0 0.00 22 7 24.14 - - - DEFB105A 0 genome.wustl.edu 37 8 7679549 7679549 + Missense_Mutation SNP C C T TCGA-A8-A086-01A-11W-A019-09 TCGA-A8-A086-10A-01W-A021-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 13d89926-9e4c-434f-80b4-4fb15e4426f6 1af700be-a789-4f68-bd75-290aeed2fd7b 8 7679549 7679549 C T SNP DEFB105A ENST00000334773 human ensembl 69_37n -1 known missense c.218 p.C73Y 0.244 NULL NULL - no_errors DEFB105A HGNC ENSG00000186562 36 0 0.00 22 3 12.00 - - - DFFB 0 genome.wustl.edu 37 1 3782540 3782540 + Missense_Mutation SNP G G A TCGA-A8-A086-01A-11W-A019-09 TCGA-A8-A086-10A-01W-A021-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 13d89926-9e4c-434f-80b4-4fb15e4426f6 1af700be-a789-4f68-bd75-290aeed2fd7b 1 3782540 3782540 G A SNP DFFB ENST00000378209 human ensembl 69_37n +1 known missense c.406 p.A136T 0.015 pfam_Apoptosis_DFF40 pfam_Apoptosis_DFF40,pfam_CAD,smart_CAD,pfscan_CAD - no_errors DFFB HGNC ENSG00000169598 10 0 0.00 12 8 40.00 - - - FBXO24 0 genome.wustl.edu 37 7 100187288 100187289 + Frame_Shift_Ins INS - - G TCGA-A8-A086-01A-11W-A019-09 TCGA-A8-A086-10A-01W-A021-09 - - Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 13d89926-9e4c-434f-80b4-4fb15e4426f6 1af700be-a789-4f68-bd75-290aeed2fd7b 7 100187288 100187289 - G INS FBXO24 ENST00000427939 human ensembl 69_37n +1 known frame_shift_ins c.25_26 p.Q12fs 0.039:0.000 NULL pfam_F-box_dom_cyclin-like,pfam_Reg_chr_condens,superfamily_Reg_csome_cond/b-lactamase_inh,superfamily_F-box_dom_cyclin-like,smart_F-box_dom_cyclin-like,pfscan_F-box_dom_cyclin-like,pfscan_Reg_chr_condens - no_errors FBXO24 HGNC ENSG00000106336 10 0 0.00 18 3 14.29 - - - KIF1C 0 genome.wustl.edu 37 17 4926901 4926901 + Frame_Shift_Del DEL C C - TCGA-A8-A086-01A-11W-A019-09 TCGA-A8-A086-10A-01W-A021-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 13d89926-9e4c-434f-80b4-4fb15e4426f6 1af700be-a789-4f68-bd75-290aeed2fd7b 17 4926901 4926901 C - DEL KIF1C ENST00000320785 human ensembl 69_37n +1 known frame_shift_del c.2767 p.R923fs 1.000 NULL pfam_Kinesin_motor_dom,pfam_FHA_dom,superfamily_SMAD_FHA_domain,smart_Kinesin_motor_dom,pfscan_Kinesin_motor_dom,prints_Kinesin_motor_dom - no_errors KIF1C HGNC ENSG00000129250 21 0 0.00 6 7 53.85 - - - LYSMD3 0 genome.wustl.edu 37 5 89815283 89815284 + Frame_Shift_Del DEL CT CT - TCGA-A8-A086-01A-11W-A019-09 TCGA-A8-A086-10A-01W-A021-09 CT CT Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 13d89926-9e4c-434f-80b4-4fb15e4426f6 1af700be-a789-4f68-bd75-290aeed2fd7b 5 89815283 89815284 CT - DEL LYSMD3 ENST00000315948 human ensembl 69_37n -1 known frame_shift_del c.274_273 p.R91fs 1.000:0.998 pfam_Peptidoglycan-bd_lysin,smart_Peptidoglycan-bd_Lysin_subgr pfam_Peptidoglycan-bd_lysin,smart_Peptidoglycan-bd_Lysin_subgr - no_errors LYSMD3 HGNC ENSG00000176018 113 0 0.00 135 32 19.05 - - - MAP3K1 0 genome.wustl.edu 37 5 56177874 56177875 + Frame_Shift_Del DEL AG AG - TCGA-A8-A086-01A-11W-A019-09 TCGA-A8-A086-10A-01W-A021-09 AG AG Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 13d89926-9e4c-434f-80b4-4fb15e4426f6 1af700be-a789-4f68-bd75-290aeed2fd7b 5 56177874 56177875 AG - DEL MAP3K1 ENST00000399503 human ensembl 69_37n +1 novel frame_shift_del c.2847_2848 p.E950fs 0.928:1.000 NULL pfam_Prot_kinase_cat_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,superfamily_ARM-type_fold,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Znf_RING,pfscan_Znf_SWIM,pfscan_Prot_kinase_cat_dom - no_errors MAP3K1 HGNC ENSG00000095015 218 0 0.00 98 152 60.32 - - - NBEAL2 0 genome.wustl.edu 37 3 47047309 47047310 + Frame_Shift_Ins INS - - G TCGA-A8-A086-01A-11W-A019-09 TCGA-A8-A086-10A-01W-A021-09 - - Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 13d89926-9e4c-434f-80b4-4fb15e4426f6 1af700be-a789-4f68-bd75-290aeed2fd7b 3 47047309 47047310 - G INS NBEAL2 ENST00000450053 human ensembl 69_37n +1 known frame_shift_ins c.6773_6774 p.D2258fs 1.000:1.000 pfam_BEACH_dom,superfamily_BEACH_dom,pfscan_BEACH_dom pfam_BEACH_dom,pfam_WD40_repeat,superfamily_BEACH_dom,superfamily_WD40_repeat_dom,superfamily_ConA-like_lec_gl,superfamily_ARM-type_fold,smart_WD40_repeat,pfscan_BEACH_dom,pfscan_WD40_repeat,pfscan_WD40_repeat_dom - no_errors NBEAL2 HGNC ENSG00000160796 22 0 0.00 8 2 20.00 - - - NQO1 0 genome.wustl.edu 37 16 69744912 69744912 + Missense_Mutation SNP G G C TCGA-A8-A086-01A-11W-A019-09 TCGA-A8-A086-10A-01W-A021-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 13d89926-9e4c-434f-80b4-4fb15e4426f6 1af700be-a789-4f68-bd75-290aeed2fd7b 16 69744912 69744912 G C SNP NQO1 ENST00000320623 human ensembl 69_37n -1 known missense c.792 p.I264M 0.996 NULL pfam_Flavodoxin_fold,pfam_FMN_red - no_errors NQO1 HGNC ENSG00000181019 140 0 0.00 98 83 45.86 - - - OPN1MW 0 genome.wustl.edu 37 X 153461447 153461447 + Missense_Mutation SNP C C T TCGA-A8-A086-01A-11W-A019-09 TCGA-A8-A086-10A-01W-A021-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 13d89926-9e4c-434f-80b4-4fb15e4426f6 1af700be-a789-4f68-bd75-290aeed2fd7b X 153461447 153461447 C T SNP OPN1MW ENST00000430054 human ensembl 69_37n +1 novel missense c.409 p.R137W 1.000 pfscan_GPCR_Rhodpsn_supfam pfam_7TM_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_supfam,prints_Opsin_red/grn - no_start_codon:pseudogene:no_stop_codon:bad_bp_length_for_coding_region OPN1MW HGNC ENSG00000147380 73 0 0.00 60 11 15.49 - - - OR10J1 0 genome.wustl.edu 37 1 159409936 159409936 + Missense_Mutation SNP G G A TCGA-A8-A086-01A-11W-A019-09 TCGA-A8-A086-10A-01W-A021-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 13d89926-9e4c-434f-80b4-4fb15e4426f6 1af700be-a789-4f68-bd75-290aeed2fd7b 1 159409936 159409936 G A SNP OR10J1 ENST00000423932 human ensembl 69_37n +1 known missense c.388 p.G130R 1.000 pfam_7TM_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_supfam,prints_7TM_GPCR_Rhodpsn pfam_7TM_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_supfam,prints_Olfact_rcpt,prints_7TM_GPCR_Rhodpsn - no_errors OR10J1 HGNC ENSG00000196184 238 0 0.00 150 85 36.17 - - - PLXNC1 0 genome.wustl.edu 37 12 94620410 94620410 + Missense_Mutation SNP C C T TCGA-A8-A086-01A-11W-A019-09 TCGA-A8-A086-10A-01W-A021-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 13d89926-9e4c-434f-80b4-4fb15e4426f6 1af700be-a789-4f68-bd75-290aeed2fd7b 12 94620410 94620410 C T SNP PLXNC1 ENST00000258526 human ensembl 69_37n +1 known missense c.1820 p.A607V 0.886 superfamily_Plexin-like_fold,smart_Plexin-like pfam_Plexin_cytoplasmic_RasGAP_dom,pfam_Plexin_repeat,pfam_IPT_TIG_rcpt,superfamily_Semaphorin/CD100_Ag,superfamily_Rho_GTPase_activation_prot,superfamily_Plexin-like_fold,superfamily_Ig_E-set,smart_Semaphorin/CD100_Ag,smart_Plexin-like,smart_IPT_TIG_rcpt,pfscan_Semaphorin/CD100_Ag - no_errors PLXNC1 HGNC ENSG00000136040 190 0 0.00 183 81 30.68 - - - POLR1B 0 genome.wustl.edu 37 2 113333168 113333168 + Silent SNP C C T TCGA-A8-A086-01A-11W-A019-09 TCGA-A8-A086-10A-01W-A021-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 13d89926-9e4c-434f-80b4-4fb15e4426f6 1af700be-a789-4f68-bd75-290aeed2fd7b 2 113333168 113333168 C T SNP POLR1B ENST00000541869 human ensembl 69_37n +1 known silent c.3384 p.A1128 1.000 pfam_RNA_pol_Rpb2_7 pfam_DNA-dir_RNA_pol_su2_6,pfam_RNA_pol_bsu_protrusion,pfam_RNA_pol_Rpb2_3,pfam_RNA_pol_Rpb2_7,pfam_RNA_pol_Rpa2-specific,pfam_RNA_pol_Rpb2_2,pfam_RNA_pol_Rpb2_5 - no_errors POLR1B HGNC ENSG00000125630 241 0 0.00 169 83 32.94 - - - SBF1 0 genome.wustl.edu 37 22 50899119 50899119 + Frame_Shift_Del DEL T T - TCGA-A8-A086-01A-11W-A019-09 TCGA-A8-A086-10A-01W-A021-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 13d89926-9e4c-434f-80b4-4fb15e4426f6 1af700be-a789-4f68-bd75-290aeed2fd7b 22 50899119 50899119 T - DEL SBF1 ENST00000380817 human ensembl 69_37n -1 known frame_shift_del c.2990 p.E997fs 1.000 NULL pfam_SBF2,pfam_DENN_dom,pfam_uDENN_dom,pfam_Myotub-related,pfam_dDENN_dom,pfam_GRAM,pfam_Pleckstrin_homology,smart_uDENN_dom,smart_DENN_dom,smart_dDENN_dom,smart_GRAM,smart_Pleckstrin_homology,pfscan_DENN_dom,pfscan_uDENN_dom,pfscan_dDENN_dom,pfscan_Pleckstrin_homology - no_errors SBF1 HGNC ENSG00000100241 62 0 0.00 18 2 10.00 - - - SH3TC1 0 genome.wustl.edu 37 4 8242514 8242514 + Silent SNP G G A TCGA-A8-A086-01A-11W-A019-09 TCGA-A8-A086-10A-01W-A021-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 13d89926-9e4c-434f-80b4-4fb15e4426f6 1af700be-a789-4f68-bd75-290aeed2fd7b 4 8242514 8242514 G A SNP SH3TC1 ENST00000245105 human ensembl 69_37n +1 known silent c.3843 p.T1281 0.071 NULL superfamily_SH3_domain,smart_SH3_domain,smart_TPR_repeat,pfscan_SH3_domain - no_errors SH3TC1 HGNC ENSG00000125089 12 0 0.00 10 5 33.33 - - - SLC41A1 0 genome.wustl.edu 37 1 205764571 205764571 + Missense_Mutation SNP G G A TCGA-A8-A086-01A-11W-A019-09 TCGA-A8-A086-10A-01W-A021-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 13d89926-9e4c-434f-80b4-4fb15e4426f6 1af700be-a789-4f68-bd75-290aeed2fd7b 1 205764571 205764571 G A SNP SLC41A1 ENST00000367137 human ensembl 69_37n -1 known missense c.1108 p.R370C 1.000 pfam_MgtE_Mg_transptr_membr pfam_MgtE_Mg_transptr_membr - no_errors SLC41A1 HGNC ENSG00000133065 34 0 0.00 38 21 35.59 - - - SLC6A11 0 genome.wustl.edu 37 3 10967723 10967723 + Missense_Mutation SNP C C T TCGA-A8-A086-01A-11W-A019-09 TCGA-A8-A086-10A-01W-A021-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 13d89926-9e4c-434f-80b4-4fb15e4426f6 1af700be-a789-4f68-bd75-290aeed2fd7b 3 10967723 10967723 C T SNP SLC6A11 ENST00000254488 human ensembl 69_37n +1 known missense c.1154 p.A385V 1.000 pfam_Na/ntran_symport,pfscan_Na/ntran_symport pfam_Na/ntran_symport,superfamily_S-AdoMet_deCO2ase_core,prints_Na/ntran_symport,prints_Na/ntran_symport_GABA_GAT3,pfscan_Na/ntran_symport - no_errors SLC6A11 HGNC ENSG00000132164 485 0 0.00 290 153 34.38 - - - SON 0 genome.wustl.edu 37 21 34924651 34924651 + Missense_Mutation SNP G G A TCGA-A8-A086-01A-11W-A019-09 TCGA-A8-A086-10A-01W-A021-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 13d89926-9e4c-434f-80b4-4fb15e4426f6 1af700be-a789-4f68-bd75-290aeed2fd7b 21 34924651 34924651 G A SNP SON ENST00000436227 human ensembl 69_37n +1 novel missense c.98 p.S33N 1.000 NULL pfam_G_patch_dom,pfam_Ds-RNA-bd,smart_G_patch_dom,smart_Ds-RNA-bd,pfscan_G_patch_dom,pfscan_Ds-RNA-bd - no_start_codon:pseudogene:no_stop_codon:bad_bp_length_for_coding_region SON HGNC ENSG00000159140 128 0 0.00 64 10 13.51 - - - TARBP2 0 genome.wustl.edu 37 12 53899836 53899837 + Frame_Shift_Del DEL TG TG - TCGA-A8-A086-01A-11W-A019-09 TCGA-A8-A086-10A-01W-A021-09 TG TG Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 13d89926-9e4c-434f-80b4-4fb15e4426f6 1af700be-a789-4f68-bd75-290aeed2fd7b 12 53899836 53899837 TG - DEL TARBP2 ENST00000266987 human ensembl 69_37n +1 known frame_shift_del c.1005_1006 p.C337fs 0.050:1.000 smart_Ds-RNA-bd,pfscan_Ds-RNA-bd pfam_Ds-RNA-bd,smart_Ds-RNA-bd,pfscan_Ds-RNA-bd - no_errors TARBP2 HGNC ENSG00000139546 27 0 0.00 19 6 24.00 - - - TMCC1 0 genome.wustl.edu 37 3 129546835 129546835 + Missense_Mutation SNP C C A TCGA-A8-A086-01A-11W-A019-09 TCGA-A8-A086-10A-01W-A021-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 13d89926-9e4c-434f-80b4-4fb15e4426f6 1af700be-a789-4f68-bd75-290aeed2fd7b 3 129546835 129546835 C A SNP TMCC1 ENST00000393238 human ensembl 69_37n -1 known missense c.387 p.E129D 0.588 NULL pfam_Predicted_TM_coiled-coil_2 - no_errors TMCC1 HGNC ENSG00000172765 101 0 0.00 95 50 34.48 - - - UBASH3A 0 genome.wustl.edu 37 21 43833311 43833311 + Missense_Mutation SNP C C T TCGA-A8-A086-01A-11W-A019-09 TCGA-A8-A086-10A-01W-A021-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 13d89926-9e4c-434f-80b4-4fb15e4426f6 1af700be-a789-4f68-bd75-290aeed2fd7b 21 43833311 43833311 C T SNP UBASH3A ENST00000319294 human ensembl 69_37n +1 known missense c.533 p.T178M 0.107 NULL pfam_His_Pase_superF_clade-1,pfam_SH3_domain,superfamily_SH3_domain,superfamily_UBA-like,smart_SH3_domain,pfscan_SH3_domain,pfscan_UBA/transl_elong_EF1B_N_euk - no_errors UBASH3A HGNC ENSG00000160185 129 0 0.00 89 42 32.06 - - - UBIAD1 0 genome.wustl.edu 37 1 11333899 11333899 + Missense_Mutation SNP A A C TCGA-A8-A086-01A-11W-A019-09 TCGA-A8-A086-10A-01W-A021-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 13d89926-9e4c-434f-80b4-4fb15e4426f6 1af700be-a789-4f68-bd75-290aeed2fd7b 1 11333899 11333899 A C SNP UBIAD1 ENST00000376810 human ensembl 69_37n +1 known missense c.311 p.Y104S 1.000 pfam_UbiA_prenyltransferase pfam_UbiA_prenyltransferase - no_errors UBIAD1 HGNC ENSG00000120942 44 0 0.00 18 7 26.92 - - - WDR36 0 genome.wustl.edu 37 5 110462515 110462515 + Silent SNP C C A TCGA-A8-A086-01A-11W-A019-09 TCGA-A8-A086-10A-01W-A021-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 13d89926-9e4c-434f-80b4-4fb15e4426f6 1af700be-a789-4f68-bd75-290aeed2fd7b 5 110462515 110462515 C A SNP WDR36 ENST00000506538 human ensembl 69_37n +1 known silent c.2790 p.T930 0.998 pfam_SSU_processome_Utp21 pfam_SSU_processome_Utp21,pfam_WD40_repeat,superfamily_Quinonprotein_ADH-like,superfamily_WD40_repeat_dom,smart_WD40_repeat,pfscan_WD40_repeat,pfscan_WD40_repeat_dom - no_errors WDR36 HGNC ENSG00000134987 162 0 0.00 80 113 58.25 - - -