Hugo_Symbol Entrez_Gene_Id Center NCBI_Build Chromosome Start_Position End_Position Strand Variant_Classification Variant_Type Reference_Allele Tumor_Seq_Allele1 Tumor_Seq_Allele2 dbSNP_RS dbSNP_Val_Status Tumor_Sample_Barcode Matched_Norm_Sample_Barcode Match_Norm_Seq_Allele1 Match_Norm_Seq_Allele2 Tumor_Validation_Allele1 Tumor_Validation_Allele2 Match_Norm_Validation_Allele1 Match_Norm_Validation_Allele2 Verification_Status Validation_Status Mutation_Status Sequencing_Phase Sequence_Source Validation_Method Score BAM_File Sequencer Tumor_Sample_UUID Matched_Norm_Sample_UUID chromosome_name_WU start_WU stop_WU reference_WU variant_WU type_WU gene_name_WU transcript_name_WU transcript_species_WU transcript_source_WU transcript_version_WU strand_WU transcript_status_WU trv_type_WU c_position_WU amino_acid_change_WU ucsc_cons_WU domain_WU all_domains_WU deletion_substructures_WU transcript_error_WU default_gene_name_WU gene_name_source_WU ensembl_gene_id normal_ref_reads normal_var_reads normal_vaf tumor_ref_reads tumors_var_reads tumor_vaf EVS_EA EVS_AA EVS_All ADAMTS6 0 genome.wustl.edu 37 5 64748575 64748575 + Missense_Mutation SNP G G A TCGA-AO-A12B-01A-11D-A10M-09 TCGA-AO-A12B-10A-01D-A10M-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 865ebd77-7b7d-4a27-b945-df5ec8d1f86a ce0e2cbf-a483-4093-b46a-32d1f14ea2f9 5 64748575 64748575 G A SNP ADAMTS6 ENST00000381055 human ensembl 69_37n -1 known missense c.802 p.R268C 1.000 pfam_Peptidase_M12B,pfscan_Peptidase_M12B pfam_ADAM_spacer1,pfam_Peptidase_M12B_N,pfam_Peptidase_M12B,pfam_Thrombospondin_1_rpt,pfam_PLAC,superfamily_Thrombospondin_1_rpt,smart_Thrombospondin_1_rpt,prints_Peptidase_M12B_ADAM-TS,pfscan_PLAC,pfscan_Thrombospondin_1_rpt,pfscan_Peptidase_M12B - no_errors ADAMTS6 HGNC ENSG00000049192 119 1 0.83 134 108 44.44 - - - AMY2A 0 genome.wustl.edu 37 1 104162362 104162362 + Missense_Mutation SNP A A T TCGA-AO-A12B-01A-11D-A10M-09 TCGA-AO-A12B-10A-01D-A10M-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 865ebd77-7b7d-4a27-b945-df5ec8d1f86a ce0e2cbf-a483-4093-b46a-32d1f14ea2f9 1 104162362 104162362 A T SNP AMY2A ENST00000414303 human ensembl 69_37n +1 known missense c.700 p.S234C 0.994 pfam_Glyco_hydro_13_cat_dom,superfamily_Glycoside_hydrolase_SF,smart_Glyco_hydro_13_sub_cat_dom pfam_Glyco_hydro_13_cat_dom,pfam_A-amylase_b_C,superfamily_Glycoside_hydrolase_SF,smart_Glyco_hydro_13_sub_cat_dom,smart_A-amylase_b_C,prints_Alpha_amylase - no_errors AMY2A HGNC ENSG00000243480 91 0 0.00 22 10 31.25 - - - ANGPT2 0 genome.wustl.edu 37 8 6420368 6420368 + Missense_Mutation SNP C C G TCGA-AO-A12B-01A-11D-A10M-09 TCGA-AO-A12B-10A-01D-A10M-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 865ebd77-7b7d-4a27-b945-df5ec8d1f86a ce0e2cbf-a483-4093-b46a-32d1f14ea2f9 8 6420368 6420368 C G SNP ANGPT2 ENST00000325203 human ensembl 69_37n -1 known missense c.88 p.G30R 0.980 NULL pfam_Fibrinogen_a/b/g_C,superfamily_Fibrinogen_a/b/g_C,smart_Fibrinogen_a/b/g_C - no_errors ANGPT2 HGNC ENSG00000091879 49 0 0.00 95 18 15.93 - - - CTCF 0 genome.wustl.edu 37 16 67644796 67644799 + Frame_Shift_Del DEL GAGA GAGA - TCGA-AO-A12B-01A-11D-A10M-09 TCGA-AO-A12B-10A-01D-A10M-09 GAGA GAGA Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 865ebd77-7b7d-4a27-b945-df5ec8d1f86a ce0e2cbf-a483-4093-b46a-32d1f14ea2f9 16 67644796 67644799 GAGA - DEL CTCF ENST00000264010 human ensembl 69_37n +1 known frame_shift_del c.61_64 p.K23fs 1.000:1.000:1.000:1.000 NULL pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2 - no_errors CTCF HGNC ENSG00000102974 34 0 0.00 10 17 62.96 - - - DNM3 0 genome.wustl.edu 37 1 171958092 171958092 + Missense_Mutation SNP T T A TCGA-AO-A12B-01A-11D-A10M-09 TCGA-AO-A12B-10A-01D-A10M-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 865ebd77-7b7d-4a27-b945-df5ec8d1f86a ce0e2cbf-a483-4093-b46a-32d1f14ea2f9 1 171958092 171958092 T A SNP DNM3 ENST00000358155 human ensembl 69_37n +1 known missense c.393 p.N131K 1.000 pfam_Dynamin_GTPase,smart_Dynamin_GTPase,prints_Dynamin pfam_Dynamin_central,pfam_Dynamin_GTPase,pfam_GED,pfam_Pleckstrin_homology,smart_Dynamin_GTPase,smart_Pleckstrin_homology,smart_GED,pfscan_Pleckstrin_homology,prints_Dynamin - no_errors DNM3 HGNC ENSG00000197959 75 0 0.00 60 17 22.08 - - - GGT3P 0 genome.wustl.edu 37 22 18769203 18769203 + RNA SNP G G A TCGA-AO-A12B-01A-11D-A10M-09 TCGA-AO-A12B-10A-01D-A10M-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 865ebd77-7b7d-4a27-b945-df5ec8d1f86a ce0e2cbf-a483-4093-b46a-32d1f14ea2f9 22 18769203 18769203 G A SNP GGT3P ENST00000412448 human ensembl 69_37n -1 known rna NULL NULL 0.149 - - - no_errors GGT3P HGNC ENSG00000197421 26 0 0.00 99 19 16.10 - - - LIMA1 0 genome.wustl.edu 37 12 50616076 50616076 + Missense_Mutation SNP G G T TCGA-AO-A12B-01A-11D-A10M-09 TCGA-AO-A12B-10A-01D-A10M-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 865ebd77-7b7d-4a27-b945-df5ec8d1f86a ce0e2cbf-a483-4093-b46a-32d1f14ea2f9 12 50616076 50616076 G T SNP LIMA1 ENST00000394943 human ensembl 69_37n -1 known missense c.358 p.Q120K 0.006 NULL pfam_Znf_LIM,smart_Znf_LIM,pfscan_Znf_LIM - no_errors LIMA1 HGNC ENSG00000050405 127 0 0.00 80 103 56.28 - - - NNT 0 genome.wustl.edu 37 5 43616033 43616033 + Missense_Mutation SNP T T G TCGA-AO-A12B-01A-11D-A10M-09 TCGA-AO-A12B-10A-01D-A10M-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 865ebd77-7b7d-4a27-b945-df5ec8d1f86a ce0e2cbf-a483-4093-b46a-32d1f14ea2f9 5 43616033 43616033 T G SNP NNT ENST00000264663 human ensembl 69_37n +1 known missense c.465 p.I155M 1.000 pfam_AlaDH/PNT_N,tigrfam_NADP_transhyd_a pfam_NADH_DH_b,pfam_AlaDH/PNT_NAD(H)-bd,pfam_AlaDH/PNT_N,tigrfam_NADP_transhyd_a - no_errors NNT HGNC ENSG00000112992 158 0 0.00 126 120 48.39 - - - OR8D1 0 genome.wustl.edu 37 11 124179975 124179976 + Frame_Shift_Ins INS - - AT TCGA-AO-A12B-01A-11D-A10M-09 TCGA-AO-A12B-10A-01D-A10M-09 - - Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 865ebd77-7b7d-4a27-b945-df5ec8d1f86a ce0e2cbf-a483-4093-b46a-32d1f14ea2f9 11 124179975 124179976 - AT INS OR8D1 ENST00000357821 human ensembl 69_37n -1 known frame_shift_ins c.688_687 p.S229fs 0.020:0.000 pfam_7TM_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_supfam pfam_7TM_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_supfam,prints_Olfact_rcpt,prints_7TM_GPCR_Rhodpsn - no_errors OR8D1 HGNC ENSG00000196341 47 0 0.00 25 5 16.67 - - - OSBPL8 0 genome.wustl.edu 37 12 76786476 76786476 + Missense_Mutation SNP G G A TCGA-AO-A12B-01A-11D-A10M-09 TCGA-AO-A12B-10A-01D-A10M-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 865ebd77-7b7d-4a27-b945-df5ec8d1f86a ce0e2cbf-a483-4093-b46a-32d1f14ea2f9 12 76786476 76786476 G A SNP OSBPL8 ENST00000261183 human ensembl 69_37n -1 known missense c.814 p.R272C 1.000 NULL pfam_Oxysterol-bd,pfam_Pleckstrin_homology,smart_Pleckstrin_homology,pfscan_Pleckstrin_homology - no_errors OSBPL8 HGNC ENSG00000091039 160 1 0.62 203 78 27.76 - - - PRKCQ 0 genome.wustl.edu 37 10 6470185 6470185 + Missense_Mutation SNP T T C TCGA-AO-A12B-01A-11D-A10M-09 TCGA-AO-A12B-10A-01D-A10M-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 865ebd77-7b7d-4a27-b945-df5ec8d1f86a ce0e2cbf-a483-4093-b46a-32d1f14ea2f9 10 6470185 6470185 T C SNP PRKCQ ENST00000263125 human ensembl 69_37n -1 known missense c.2105 p.E702G 0.980 pirsf_Prot_kin_PKC_delta pfam_Prot_kinase_cat_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_Kinase_C-like_PE/DAG-bd,pfam_Pkinase_C,superfamily_Kinase-like_dom,superfamily_C2_Ca/lipid-bd_dom_CaLB,smart_Prot_Kinase_C-like_PE/DAG-bd,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,smart_AGC-kinase_C,pirsf_Prot_kin_PKC_delta,prints_DAG/PE-bd,prints_Ser-Thr/Tyr_kinase_cat_dom,pfscan_Prot_Kinase_C-like_PE/DAG-bd,pfscan_Prot_kinase_cat_dom - no_errors PRKCQ HGNC ENSG00000065675 89 0 0.00 109 20 15.38 - - - PTPN14 0 genome.wustl.edu 37 1 214543010 214543010 + Nonsense_Mutation SNP G G A TCGA-AO-A12B-01A-11D-A10M-09 TCGA-AO-A12B-10A-01D-A10M-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 865ebd77-7b7d-4a27-b945-df5ec8d1f86a ce0e2cbf-a483-4093-b46a-32d1f14ea2f9 1 214543010 214543010 G A SNP PTPN14 ENST00000366956 human ensembl 69_37n -1 known nonsense c.3061 p.R1021* 1.000 pfam_Tyr_Pase_rcpt/non-rcpt,smart_Tyr_Pase_rcpt/non-rcpt,pirsf_Tyr_Pase_non-rcpt_typ-14/21,pfscan_Tyr_Pase_rcpt/non-rcpt pfam_Tyr_Pase_rcpt/non-rcpt,pfam_FERM_central,pfam_FERM_N,pfam_FERM_PH-like_C,pfam_Dual-sp_phosphatase_cat-dom,superfamily_FERM_central,smart_Band_41_domain,smart_Tyr_Pase_rcpt/non-rcpt,smart_Tyr_Pase_cat,pirsf_Tyr_Pase_non-rcpt_typ-14/21,pfscan_FERM_domain,pfscan_Tyr/Dual-specificity_Pase,pfscan_Tyr_Pase_rcpt/non-rcpt,prints_Tyr_Pase_rcpt/non-rcpt,prints_Band_41_fam - no_errors PTPN14 HGNC ENSG00000152104 87 0 0.00 200 45 18.37 - - - RFPL4A 0 genome.wustl.edu 37 19 56274382 56274382 + Silent SNP G G T TCGA-AO-A12B-01A-11D-A10M-09 TCGA-AO-A12B-10A-01D-A10M-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 865ebd77-7b7d-4a27-b945-df5ec8d1f86a ce0e2cbf-a483-4093-b46a-32d1f14ea2f9 19 56274382 56274382 G T SNP RFPL4A ENST00000434937 human ensembl 69_37n +1 novel silent c.705 p.G235 0.001 pfam_SPRY_rcpt,superfamily_ConA-like_lec_gl,smart_SPla/RYanodine_receptor_subgr,pfscan_B30.2/SPRY pfam_RDM_domain_RFPL,pfam_SPRY_rcpt,superfamily_ConA-like_lec_gl,smart_PRY,smart_SPla/RYanodine_receptor_subgr,pfscan_B30.2/SPRY,pfscan_Znf_RING,prints_Butyrophylin - no_errors RFPL4A HGNC ENSG00000223638 543 0 0.00 788 97 10.96 - - - TRHDE 0 genome.wustl.edu 37 12 72956810 72956810 + Nonsense_Mutation SNP C C T TCGA-AO-A12B-01A-11D-A10M-09 TCGA-AO-A12B-10A-01D-A10M-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 865ebd77-7b7d-4a27-b945-df5ec8d1f86a ce0e2cbf-a483-4093-b46a-32d1f14ea2f9 12 72956810 72956810 C T SNP TRHDE ENST00000261180 human ensembl 69_37n +1 known nonsense c.1897 p.Q633* 0.925 NULL pfam_Peptidase_M1_N,prints_Peptidase_M1_N - no_errors TRHDE HGNC ENSG00000072657 105 0 0.00 25 30 54.55 - - - TRPC4 0 genome.wustl.edu 37 13 38357162 38357162 + Silent SNP A A G TCGA-AO-A12B-01A-11D-A10M-09 TCGA-AO-A12B-10A-01D-A10M-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 865ebd77-7b7d-4a27-b945-df5ec8d1f86a ce0e2cbf-a483-4093-b46a-32d1f14ea2f9 13 38357162 38357162 A G SNP TRPC4 ENST00000379681 human ensembl 69_37n -1 known silent c.309 p.A103 0.418 superfamily_Ankyrin_rpt-contain_dom,tigrfam_TRP_channel pfam_Ion_trans_dom,pfam_TRP_dom,superfamily_Ankyrin_rpt-contain_dom,smart_Ankyrin_rpt,prints_TRPC4_channel,prints_TRPC_channel,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,tigrfam_TRP_channel - no_errors TRPC4 HGNC ENSG00000133107 68 0 0.00 20 13 39.39 - - - USP32 0 genome.wustl.edu 37 17 58260550 58260550 + Missense_Mutation SNP C C T TCGA-AO-A12B-01A-11D-A10M-09 TCGA-AO-A12B-10A-01D-A10M-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 865ebd77-7b7d-4a27-b945-df5ec8d1f86a ce0e2cbf-a483-4093-b46a-32d1f14ea2f9 17 58260550 58260550 C T SNP USP32 ENST00000300896 human ensembl 69_37n -1 known missense c.4099 p.A1367T 0.787 pfam_Peptidase_C19,pfscan_Peptidase_C19 pfam_Peptidase_C19,pfam_Pept_C19_DUSP,smart_EF_hand_Ca-bd,smart_Pept_C19_DUSP,pfscan_EF_HAND_2,pfscan_Peptidase_C19,prints_Recoverin - no_errors USP32 HGNC ENSG00000170832 51 0 0.00 38 27 41.54 - - - ZNF717 0 genome.wustl.edu 37 3 75787068 75787069 + Frame_Shift_Ins INS - - T TCGA-AO-A12B-01A-11D-A10M-09 TCGA-AO-A12B-10A-01D-A10M-09 - - Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 865ebd77-7b7d-4a27-b945-df5ec8d1f86a ce0e2cbf-a483-4093-b46a-32d1f14ea2f9 3 75787068 75787069 - T INS ZNF717 ENST00000422325 human ensembl 69_37n -1 known frame_shift_ins c.1706_1705 p.G569fs 0.996:0.998 smart_Znf_C2H2-like,pfscan_Znf_C2H2 pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box - no_errors ZNF717 HGNC ENSG00000227124 42 0 0.00 11 2 15.38 - - -