Hugo_Symbol Entrez_Gene_Id Center NCBI_Build Chromosome Start_Position End_Position Strand Variant_Classification Variant_Type Reference_Allele Tumor_Seq_Allele1 Tumor_Seq_Allele2 dbSNP_RS dbSNP_Val_Status Tumor_Sample_Barcode Matched_Norm_Sample_Barcode Match_Norm_Seq_Allele1 Match_Norm_Seq_Allele2 Tumor_Validation_Allele1 Tumor_Validation_Allele2 Match_Norm_Validation_Allele1 Match_Norm_Validation_Allele2 Verification_Status Validation_Status Mutation_Status Sequencing_Phase Sequence_Source Validation_Method Score BAM_File Sequencer Tumor_Sample_UUID Matched_Norm_Sample_UUID chromosome_name_WU start_WU stop_WU reference_WU variant_WU type_WU gene_name_WU transcript_name_WU transcript_species_WU transcript_source_WU transcript_version_WU strand_WU transcript_status_WU trv_type_WU c_position_WU amino_acid_change_WU ucsc_cons_WU domain_WU all_domains_WU deletion_substructures_WU transcript_error_WU default_gene_name_WU gene_name_source_WU ensembl_gene_id normal_ref_reads normal_var_reads normal_vaf tumor_ref_reads tumors_var_reads tumor_vaf EVS_EA EVS_AA EVS_All ATP10B 0 genome.wustl.edu 37 5 160097495 160097495 + Missense_Mutation SNP C C T TCGA-AR-A1AS-01A-11D-A12Q-09 TCGA-AR-A1AS-10A-01D-A12Q-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 3f26f93c-e11a-4ec9-b73b-98fcadc209f4 97a055bf-af49-4c79-bc12-0b3644f21638 5 160097495 160097495 C T SNP ATP10B ENST00000327245 human ensembl 69_37n -1 known missense c.650 p.C217Y 0.712 pfam_ATPase_P-typ_ATPase-assoc-dom,tigrfam_ATPase_P-typ_Plipid-transl pfam_ATPase_P-typ_ATPase-assoc-dom,pfam_Dehalogen-like_hydro,superfamily_HAD-like_dom,superfamily_ATPase_cation_domN,prints_ATPase_P-typ_ion-transptr,tigrfam_ATPase_P-typ_Plipid-transl,tigrfam_ATPase_P-typ_ion-transptr - no_errors ATP10B HGNC ENSG00000118322 256 2 0.78 89 42 32.06 - - - BCL11A 0 genome.wustl.edu 37 2 60687616 60687616 + Missense_Mutation SNP C C T TCGA-AR-A1AS-01A-11D-A12Q-09 TCGA-AR-A1AS-10A-01D-A12Q-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 3f26f93c-e11a-4ec9-b73b-98fcadc209f4 97a055bf-af49-4c79-bc12-0b3644f21638 2 60687616 60687616 C T SNP BCL11A ENST00000335712 human ensembl 69_37n -1 known missense c.2431 p.V811M 1.000 pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2 pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2 - no_errors BCL11A HGNC ENSG00000119866 100 0 0.00 27 18 40.00 - - - C1orf111 0 genome.wustl.edu 37 1 162343895 162343895 + Silent SNP G G A TCGA-AR-A1AS-01A-11D-A12Q-09 TCGA-AR-A1AS-10A-01D-A12Q-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 3f26f93c-e11a-4ec9-b73b-98fcadc209f4 97a055bf-af49-4c79-bc12-0b3644f21638 1 162343895 162343895 G A SNP C1orf111 ENST00000367935 human ensembl 69_37n -1 known silent c.729 p.F243 1.000 NULL NULL - no_errors C1orf111 HGNC ENSG00000171722 66 0 0.00 60 7 10.45 - - - CNGA4 0 genome.wustl.edu 37 11 6261794 6261794 + Missense_Mutation SNP G G A TCGA-AR-A1AS-01A-11D-A12Q-09 TCGA-AR-A1AS-10A-01D-A12Q-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 3f26f93c-e11a-4ec9-b73b-98fcadc209f4 97a055bf-af49-4c79-bc12-0b3644f21638 11 6261794 6261794 G A SNP CNGA4 ENST00000379936 human ensembl 69_37n +1 known missense c.770 p.G257D 1.000 pfam_Ion_trans_dom pfam_cNMP-bd_dom,pfam_Ion_trans_dom,superfamily_cNMP-bd-like,smart_cNMP-bd_dom,pfscan_cNMP-bd_dom - no_errors CNGA4 HGNC ENSG00000132259 50 0 0.00 19 10 34.48 - - - EIF4A3 0 genome.wustl.edu 37 17 78110120 78110120 + Missense_Mutation SNP G G C TCGA-AR-A1AS-01A-11D-A12Q-09 TCGA-AR-A1AS-10A-01D-A12Q-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 3f26f93c-e11a-4ec9-b73b-98fcadc209f4 97a055bf-af49-4c79-bc12-0b3644f21638 17 78110120 78110120 G C SNP EIF4A3 ENST00000269349 human ensembl 69_37n -1 known missense c.998 p.S333C 0.890 pfam_Helicase_C,smart_Helicase_C,pfscan_Helicase_C pfam_DNA/RNA_helicase_DEAD/DEAH_N,pfam_Helicase_C,smart_Helicase_ATP-bd,smart_Helicase_C,pfscan_Helicase_ATP-bd,pfscan_Helicase_C,pfscan_RNA_helicase_DEAD_Q_motif - no_errors EIF4A3 HGNC ENSG00000141543 184 0 0.00 52 16 23.53 - - - EPHB6 0 genome.wustl.edu 37 7 142568630 142568630 + Silent SNP G G A TCGA-AR-A1AS-01A-11D-A12Q-09 TCGA-AR-A1AS-10A-01D-A12Q-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 3f26f93c-e11a-4ec9-b73b-98fcadc209f4 97a055bf-af49-4c79-bc12-0b3644f21638 7 142568630 142568630 G A SNP EPHB6 ENST00000392957 human ensembl 69_37n +1 known silent c.3039 p.L1013 1.000 pirsf_Tyr_kinase_ephrin_rcpt,superfamily_SAM/pointed pirsf_Tyr_kinase_ephrin_rcpt,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Ephrin_rcpt_lig-bd_dom,pfam_Prot_kinase_cat_dom,pfam_Fibronectin_type3,pfam_SAM_2,pfam_SAM_type1,pfam_Tyr-kin_ephrin_A/B_rcpt-like,superfamily_Galactose-bd-like,superfamily_Kinase-like_dom,superfamily_Fibronectin_type3,superfamily_SAM/pointed,superfamily_Growth_fac_rcpt,smart_Ephrin_rcpt_lig-bd_dom,smart_Fibronectin_type3,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,smart_SAM,prints_Ser-Thr/Tyr_kinase_cat_dom,pfscan_Fibronectin_type3,pfscan_SAM,pfscan_Prot_kinase_cat_dom - no_errors EPHB6 HGNC ENSG00000106123 30 0 0.00 22 17 43.59 - - - EYA2 0 genome.wustl.edu 37 20 45801427 45801427 + Silent SNP G G A TCGA-AR-A1AS-01A-11D-A12Q-09 TCGA-AR-A1AS-10A-01D-A12Q-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 3f26f93c-e11a-4ec9-b73b-98fcadc209f4 97a055bf-af49-4c79-bc12-0b3644f21638 20 45801427 45801427 G A SNP EYA2 ENST00000327619 human ensembl 69_37n +1 known silent c.1110 p.V370 0.330 pfam_Dehalogen-like_hydro,tigrfam_EYA pfam_Dehalogen-like_hydro,superfamily_HAD-like_dom,tigrfam_EYA - no_errors EYA2 HGNC ENSG00000064655 127 0 0.00 87 12 12.12 - - - FAM157B 0 genome.wustl.edu 37 9 141107536 141107537 + RNA INS - - GCA TCGA-AR-A1AS-01A-11D-A12Q-09 TCGA-AR-A1AS-10A-01D-A12Q-09 - - Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 3f26f93c-e11a-4ec9-b73b-98fcadc209f4 97a055bf-af49-4c79-bc12-0b3644f21638 9 141107536 141107537 - GCA INS FAM157B ENST00000446912 human ensembl 69_37n +1 known rna NULL NULL 0.033:0.036 - - - no_errors FAM157B HGNC ENSG00000233013 61 0 0.00 28 4 12.50 - - - FUOM 0 genome.wustl.edu 37 10 135170746 135170746 + Silent SNP C C T TCGA-AR-A1AS-01A-11D-A12Q-09 TCGA-AR-A1AS-10A-01D-A12Q-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 3f26f93c-e11a-4ec9-b73b-98fcadc209f4 97a055bf-af49-4c79-bc12-0b3644f21638 10 135170746 135170746 C T SNP FUOM ENST00000368552 human ensembl 69_37n -1 known silent c.99 p.L33 0.275 pfam_RbsD_FucU,superfamily_RbsD-like pfam_RbsD_FucU,superfamily_RbsD-like - no_errors FUOM HGNC ENSG00000148803 35 0 0.00 23 7 23.33 - - - GATA3 0 genome.wustl.edu 37 10 8100440 8100440 + Silent SNP C C G TCGA-AR-A1AS-01A-11D-A12Q-09 TCGA-AR-A1AS-10A-01D-A12Q-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 3f26f93c-e11a-4ec9-b73b-98fcadc209f4 97a055bf-af49-4c79-bc12-0b3644f21638 10 8100440 8100440 C G SNP GATA3 ENST00000379328 human ensembl 69_37n +1 known silent c.414 p.S138 0.884 pirsf_TF_GATA-1/2/3 pfam_Znf_GATA,smart_Znf_GATA,pirsf_TF_GATA-1/2/3,pfscan_Znf_GATA,prints_Znf_GATA - no_errors GATA3 HGNC ENSG00000107485 42 0 0.00 18 10 35.71 - - - GIMAP4 0 genome.wustl.edu 37 7 150269546 150269546 + Missense_Mutation SNP G G A TCGA-AR-A1AS-01A-11D-A12Q-09 TCGA-AR-A1AS-10A-01D-A12Q-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 3f26f93c-e11a-4ec9-b73b-98fcadc209f4 97a055bf-af49-4c79-bc12-0b3644f21638 7 150269546 150269546 G A SNP GIMAP4 ENST00000255945 human ensembl 69_37n +1 known missense c.388 p.E130K 1.000 pfam_AIG1 pfam_AIG1 - no_errors GIMAP4 HGNC ENSG00000133574 98 0 0.00 19 14 42.42 - - - GLRX2 0 genome.wustl.edu 37 1 193065756 193065756 + Nonstop_Mutation SNP C C G TCGA-AR-A1AS-01A-11D-A12Q-09 TCGA-AR-A1AS-10A-01D-A12Q-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 3f26f93c-e11a-4ec9-b73b-98fcadc209f4 97a055bf-af49-4c79-bc12-0b3644f21638 1 193065756 193065756 C G SNP GLRX2 ENST00000367440 human ensembl 69_37n -1 known nonstop c.497 p.*166S 0.093 NULL pfam_Glutaredoxin,superfamily_Thioredoxin-like_fold,prints_Glutaredoxin_subgr,tigrfam_Glutaredoxin_euk/vir - no_errors GLRX2 HGNC ENSG00000023572 193 0 0.00 103 22 17.46 - - - GOLPH3 0 genome.wustl.edu 37 5 32143957 32143957 + Missense_Mutation SNP T T C TCGA-AR-A1AS-01A-11D-A12Q-09 TCGA-AR-A1AS-10A-01D-A12Q-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 3f26f93c-e11a-4ec9-b73b-98fcadc209f4 97a055bf-af49-4c79-bc12-0b3644f21638 5 32143957 32143957 T C SNP GOLPH3 ENST00000265070 human ensembl 69_37n -1 known missense c.255 p.I85M 1.000 pfam_GPP34 pfam_GPP34 - no_errors GOLPH3 HGNC ENSG00000113384 212 0 0.00 53 49 48.04 - - - GPRIN2 0 genome.wustl.edu 37 10 46998995 46998995 + Missense_Mutation SNP C C G TCGA-AR-A1AS-01A-11D-A12Q-09 TCGA-AR-A1AS-10A-01D-A12Q-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 3f26f93c-e11a-4ec9-b73b-98fcadc209f4 97a055bf-af49-4c79-bc12-0b3644f21638 10 46998995 46998995 C G SNP GPRIN2 ENST00000374314 human ensembl 69_37n +1 known missense c.115 p.L39V 0.989 NULL NULL - no_errors GPRIN2 HGNC ENSG00000204175 10 0 0.00 8 4 33.33 - - - HMGN5 0 genome.wustl.edu 37 X 80370668 80370668 + Missense_Mutation SNP T T G TCGA-AR-A1AS-01A-11D-A12Q-09 TCGA-AR-A1AS-10A-01D-A12Q-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 3f26f93c-e11a-4ec9-b73b-98fcadc209f4 97a055bf-af49-4c79-bc12-0b3644f21638 X 80370668 80370668 T G SNP HMGN5 ENST00000358130 human ensembl 69_37n -1 known missense c.329 p.E110A 0.045 NULL pfam_HMGN_fam,smart_HMGN_fam,prints_HMGN_fam - no_errors HMGN5 HGNC ENSG00000198157 537 2 0.37 119 83 41.09 - - - IRAK3 0 genome.wustl.edu 37 12 66638269 66638269 + Silent SNP A A C TCGA-AR-A1AS-01A-11D-A12Q-09 TCGA-AR-A1AS-10A-01D-A12Q-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 3f26f93c-e11a-4ec9-b73b-98fcadc209f4 97a055bf-af49-4c79-bc12-0b3644f21638 12 66638269 66638269 A C SNP IRAK3 ENST00000261233 human ensembl 69_37n +1 known silent c.891 p.A297 0.997 pfam_Prot_kinase_cat_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_cat_dom pfam_Prot_kinase_cat_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Death,superfamily_Kinase-like_dom,superfamily_DEATH-like,smart_Death,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Death,pfscan_Prot_kinase_cat_dom - no_errors IRAK3 HGNC ENSG00000090376 156 0 0.00 38 31 44.93 - - - KRAS 0 genome.wustl.edu 37 12 25398284 25398284 + Missense_Mutation SNP C C A TCGA-AR-A1AS-01A-11D-A12Q-09 TCGA-AR-A1AS-10A-01D-A12Q-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 3f26f93c-e11a-4ec9-b73b-98fcadc209f4 97a055bf-af49-4c79-bc12-0b3644f21638 12 25398284 25398284 C A SNP KRAS ENST00000256078 human ensembl 69_37n -1 known missense c.35 p.G12V 1.000 pfam_Small_GTPase,pfam_MIRO-like,pfam_Small_GTPase_ARF/SAR,smart_Small_GTPase_Ras,smart_Small_GTPase_Rab_type,smart_Small_GTPase_Rho,smart_Ran_GTPase,prints_Small_GTPase,tigrfam_Small_GTP-bd_dom pfam_Small_GTPase,pfam_MIRO-like,pfam_Small_GTPase_ARF/SAR,pfam_ProtSyn_GTP-bd,smart_Small_GTPase_Ras,smart_Small_GTPase_Rab_type,smart_Small_GTPase_Rho,smart_Ran_GTPase,prints_Small_GTPase,tigrfam_Small_GTP-bd_dom - no_errors KRAS HGNC ENSG00000133703 264 0 0.00 82 35 29.91 - - - LARP6 0 genome.wustl.edu 37 15 71128708 71128708 + Missense_Mutation SNP C C T TCGA-AR-A1AS-01A-11D-A12Q-09 TCGA-AR-A1AS-10A-01D-A12Q-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 3f26f93c-e11a-4ec9-b73b-98fcadc209f4 97a055bf-af49-4c79-bc12-0b3644f21638 15 71128708 71128708 C T SNP LARP6 ENST00000299213 human ensembl 69_37n -1 known missense c.337 p.A113T 1.000 pfam_Lupus_La_RNA-bd,smart_Lupus_La_RNA-bd,pfscan_Lupus_La_RNA-bd,prints_Lupus_La pfam_Lupus_La_RNA-bd,smart_Lupus_La_RNA-bd,pfscan_Lupus_La_RNA-bd,prints_Lupus_La - no_errors LARP6 HGNC ENSG00000166173 156 0 0.00 41 35 45.45 - - - LCAT 0 genome.wustl.edu 37 16 67977911 67977911 + Missense_Mutation SNP A A T TCGA-AR-A1AS-01A-11D-A12Q-09 TCGA-AR-A1AS-10A-01D-A12Q-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 3f26f93c-e11a-4ec9-b73b-98fcadc209f4 97a055bf-af49-4c79-bc12-0b3644f21638 16 67977911 67977911 A T SNP LCAT ENST00000264005 human ensembl 69_37n -1 known missense c.94 p.F32I 1.000 NULL pfam_LACT/PDAT_acylTrfase - no_errors LCAT HGNC ENSG00000213398 42 0 0.00 23 24 50.00 - - - LILRB3 0 genome.wustl.edu 37 19 54726628 54726628 + Missense_Mutation SNP C C T TCGA-AR-A1AS-01A-11D-A12Q-09 TCGA-AR-A1AS-10A-01D-A12Q-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 3f26f93c-e11a-4ec9-b73b-98fcadc209f4 97a055bf-af49-4c79-bc12-0b3644f21638 19 54726628 54726628 C T SNP LILRB3 ENST00000346401 human ensembl 69_37n -1 known missense c.61 p.V21M 0.000 NULL smart_Ig_sub,smart_Ig_sub2,pfscan_Ig-like - no_errors LILRB3 HGNC ENSG00000204577 11 0 0.00 3 3 50.00 - - - LRFN5 0 genome.wustl.edu 37 14 42360996 42360996 + Silent SNP G G A TCGA-AR-A1AS-01A-11D-A12Q-09 TCGA-AR-A1AS-10A-01D-A12Q-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 3f26f93c-e11a-4ec9-b73b-98fcadc209f4 97a055bf-af49-4c79-bc12-0b3644f21638 14 42360996 42360996 G A SNP LRFN5 ENST00000298119 human ensembl 69_37n +1 known silent c.1929 p.Q643 1.000 NULL pfam_Leu-rich_rpt,pfam_Ig_I-set,pfam_Immunoglobulin,superfamily_Fibronectin_type3,smart_Leu-rich_rpt_typical-subtyp,smart_Ig_sub,smart_Ig_sub2,pfscan_Fibronectin_type3,pfscan_Ig-like - no_errors LRFN5 HGNC ENSG00000165379 157 0 0.00 44 32 42.11 - - - MAP2K4 0 genome.wustl.edu 37 17 12016634 12016634 + Missense_Mutation SNP C C T TCGA-AR-A1AS-01A-11D-A12Q-09 TCGA-AR-A1AS-10A-01D-A12Q-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 3f26f93c-e11a-4ec9-b73b-98fcadc209f4 97a055bf-af49-4c79-bc12-0b3644f21638 17 12016634 12016634 C T SNP MAP2K4 ENST00000415385 human ensembl 69_37n +1 known missense c.803 p.S268F 1.000 pfam_Prot_kinase_cat_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_cat_dom pfam_Prot_kinase_cat_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_cat_dom - no_errors MAP2K4 HGNC ENSG00000065559 120 0 0.00 13 17 56.67 - - - MAPK4 0 genome.wustl.edu 37 18 48255652 48255652 + Missense_Mutation SNP C C T TCGA-AR-A1AS-01A-11D-A12Q-09 TCGA-AR-A1AS-10A-01D-A12Q-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 3f26f93c-e11a-4ec9-b73b-98fcadc209f4 97a055bf-af49-4c79-bc12-0b3644f21638 18 48255652 48255652 C T SNP MAPK4 ENST00000400384 human ensembl 69_37n +1 known missense c.1192 p.R398C 1.000 NULL pfam_Prot_kinase_cat_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_cat_dom,prints_MAPK_ERK3/4 - no_errors MAPK4 HGNC ENSG00000141639 14 0 0.00 8 4 33.33 - - - MST1P9 0 genome.wustl.edu 37 1 17083837 17083837 + Missense_Mutation SNP T T C TCGA-AR-A1AS-01A-11D-A12Q-09 TCGA-AR-A1AS-10A-01D-A12Q-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 3f26f93c-e11a-4ec9-b73b-98fcadc209f4 97a055bf-af49-4c79-bc12-0b3644f21638 1 17083837 17083837 T C SNP MST1P9 ENST00000334998 human ensembl 69_37n -1 known missense c.1960 p.K654E 1.000 pfam_Peptidase_S1_S6,superfamily_Pept_cys/ser_Trypsin-like,smart_Peptidase_S1_S6,pfscan_Peptidase_S1_S6 pfam_Kringle,pfam_Peptidase_S1_S6,pfam_PAN-1_domain,superfamily_Pept_cys/ser_Trypsin-like,superfamily_Kringle-like,smart_Pan_app,smart_Kringle,smart_Peptidase_S1_S6,pfscan_Pan_app,pfscan_Kringle,pfscan_Peptidase_S1_S6 - no_errors MST1P9 HGNC ENSG00000186715 15 0 0.00 8 4 33.33 - - - MUC15 0 genome.wustl.edu 37 11 26582735 26582735 + Silent SNP C C T TCGA-AR-A1AS-01A-11D-A12Q-09 TCGA-AR-A1AS-10A-01D-A12Q-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 3f26f93c-e11a-4ec9-b73b-98fcadc209f4 97a055bf-af49-4c79-bc12-0b3644f21638 11 26582735 26582735 C T SNP MUC15 ENST00000436318 human ensembl 69_37n -1 known silent c.963 p.V321 0.113 NULL NULL - no_errors MUC15 HGNC ENSG00000169550 322 0 0.00 93 54 36.73 - - - MYOF 0 genome.wustl.edu 37 10 95137179 95137182 + Frame_Shift_Del DEL TTTG TTTG - TCGA-AR-A1AS-01A-11D-A12Q-09 TCGA-AR-A1AS-10A-01D-A12Q-09 TTTG TTTG Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 3f26f93c-e11a-4ec9-b73b-98fcadc209f4 97a055bf-af49-4c79-bc12-0b3644f21638 10 95137179 95137182 TTTG - DEL MYOF ENST00000359263 human ensembl 69_37n -1 known frame_shift_del c.2009_2006 p.T669fs 0.987:0.989:0.900:0.996 NULL pfam_C2_Ca-dep,pfam_Ferlin_B-domain,pfam_FerIin-domain,pfam_Ferlin_A-domain,superfamily_C2_Ca/lipid-bd_dom_CaLB,smart_C2_Ca-dep,smart_Peroxin/Ferlin,pfscan_C2_membr_targeting - no_errors MYOF HGNC ENSG00000138119 365 0 0.00 98 44 30.99 - - - NXF1 0 genome.wustl.edu 37 11 62572858 62572858 + RNA SNP G G A TCGA-AR-A1AS-01A-11D-A12Q-09 TCGA-AR-A1AS-10A-01D-A12Q-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 3f26f93c-e11a-4ec9-b73b-98fcadc209f4 97a055bf-af49-4c79-bc12-0b3644f21638 11 62572858 62572858 G A SNP NXF1 ENST00000526163 human ensembl 69_37n -1 known rna NULL NULL 0.001 - - - no_errors NXF1 HGNC ENSG00000162231 25 0 0.00 10 15 60.00 - - - PCDHA4 0 genome.wustl.edu 37 5 140187112 140187112 + Silent SNP C C T TCGA-AR-A1AS-01A-11D-A12Q-09 TCGA-AR-A1AS-10A-01D-A12Q-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 3f26f93c-e11a-4ec9-b73b-98fcadc209f4 97a055bf-af49-4c79-bc12-0b3644f21638 5 140187112 140187112 C T SNP PCDHA4 ENST00000530339 human ensembl 69_37n +1 known silent c.340 p.L114 1.000 superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin pfam_Cadherin,pfam_Cadherin_N,superfamily_Cadherin-like,smart_Cadherin,prints_Cadherin,pfscan_Cadherin - no_errors PCDHA4 HGNC ENSG00000204967 105 0 0.00 43 11 20.37 - - - PIK3CA 0 genome.wustl.edu 37 3 178936092 178936092 + Missense_Mutation SNP A A C TCGA-AR-A1AS-01A-11D-A12Q-09 TCGA-AR-A1AS-10A-01D-A12Q-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 3f26f93c-e11a-4ec9-b73b-98fcadc209f4 97a055bf-af49-4c79-bc12-0b3644f21638 3 178936092 178936092 A C SNP PIK3CA ENST00000263967 human ensembl 69_37n +1 known missense c.1634 p.E545A 1.000 pfam_PInositide-3_kin_accessory_dom,superfamily_ARM-type_fold,smart_PInositide-3_kin_accessory_dom pfam_PInositide-3_kin_accessory_dom,pfam_PI3/4_kinase_cat_dom,pfam_PI3K_Ras-bd_dom,pfam_PI3K_C2_dom,pfam_PI3K_adapt-bd_dom,superfamily_Kinase-like_dom,superfamily_ARM-type_fold,superfamily_C2_Ca/lipid-bd_dom_CaLB,smart_PI3K_adapt-bd_dom,smart_PI3K_Ras-bd_dom,smart_PI3K_C2_dom,smart_PInositide-3_kin_accessory_dom,smart_PI3/4_kinase_cat_dom,pfscan_PI3/4_kinase_cat_dom - no_errors PIK3CA HGNC ENSG00000121879 189 0 0.00 46 48 51.06 - - - PLXNA4 0 genome.wustl.edu 37 7 131848926 131848926 + Missense_Mutation SNP C C T TCGA-AR-A1AS-01A-11D-A12Q-09 TCGA-AR-A1AS-10A-01D-A12Q-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 3f26f93c-e11a-4ec9-b73b-98fcadc209f4 97a055bf-af49-4c79-bc12-0b3644f21638 7 131848926 131848926 C T SNP PLXNA4 ENST00000321063 human ensembl 69_37n -1 known missense c.4475 p.R1492H 1.000 pfam_Plexin_cytoplasmic_RasGAP_dom,superfamily_Rho_GTPase_activation_prot pfam_Plexin_cytoplasmic_RasGAP_dom,pfam_Semaphorin/CD100_Ag,pfam_IPT_TIG_rcpt,pfam_Plexin_repeat,superfamily_Semaphorin/CD100_Ag,superfamily_Rho_GTPase_activation_prot,superfamily_Ig_E-set,superfamily_Plexin-like_fold,smart_Semaphorin/CD100_Ag,smart_Plexin-like,smart_IPT_TIG_rcpt,pfscan_Semaphorin/CD100_Ag - no_errors PLXNA4 HGNC ENSG00000221866 175 0 0.00 69 44 38.94 - - - RBM6 0 genome.wustl.edu 37 3 50095901 50095901 + Missense_Mutation SNP A A G TCGA-AR-A1AS-01A-11D-A12Q-09 TCGA-AR-A1AS-10A-01D-A12Q-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 3f26f93c-e11a-4ec9-b73b-98fcadc209f4 97a055bf-af49-4c79-bc12-0b3644f21638 3 50095901 50095901 A G SNP RBM6 ENST00000266022 human ensembl 69_37n +1 known missense c.2036 p.Y679C 0.997 smart_RRM_dom pfam_G_patch_dom,smart_RRM_dom,smart_G_patch_dom,pfscan_G_patch_dom,pfscan_RRM_dom - no_errors RBM6 HGNC ENSG00000004534 110 0 0.00 43 50 53.76 - - - RYR2 0 genome.wustl.edu 37 1 237632461 237632461 + Missense_Mutation SNP G G T TCGA-AR-A1AS-01A-11D-A12Q-09 TCGA-AR-A1AS-10A-01D-A12Q-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 3f26f93c-e11a-4ec9-b73b-98fcadc209f4 97a055bf-af49-4c79-bc12-0b3644f21638 1 237632461 237632461 G T SNP RYR2 ENST00000360064 human ensembl 69_37n +1 known missense c.1676 p.R559I 1.000 pfam_Ca-rel_channel pfam_Ca-rel_channel,pfam_Ryanodine_rcpt,pfam_Ryanrecept_TM4-6,pfam_SPRY_rcpt,pfam_Ins145_P3_rcpt,pfam_MIR,pfam_RIH_assoc-dom,pfam_Ion_trans_dom,superfamily_MIR,superfamily_ConA-like_lec_gl,smart_MIR_motif,smart_SPla/RYanodine_receptor_subgr,prints_Ryan_recept,pfscan_B30.2/SPRY,pfscan_EF_HAND_2,pfscan_MIR_motif - no_errors RYR2 HGNC ENSG00000198626 363 0 0.00 229 61 20.89 - - - SLC6A9 0 genome.wustl.edu 37 1 44468079 44468079 + Missense_Mutation SNP C C A TCGA-AR-A1AS-01A-11D-A12Q-09 TCGA-AR-A1AS-10A-01D-A12Q-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 3f26f93c-e11a-4ec9-b73b-98fcadc209f4 97a055bf-af49-4c79-bc12-0b3644f21638 1 44468079 44468079 C A SNP SLC6A9 ENST00000360584 human ensembl 69_37n -1 known missense c.1087 p.D363Y 1.000 pfam_Na/ntran_symport,pfscan_Na/ntran_symport pfam_Na/ntran_symport,pfscan_Na/ntran_symport,prints_Na/ntran_symport,prints_Na/ntran_symport_glycine_GLY1 - no_errors SLC6A9 HGNC ENSG00000196517 57 0 0.00 36 4 10.00 - - - SPRR2B 0 genome.wustl.edu 37 1 153043220 153043220 + Nonsense_Mutation SNP G G T TCGA-AR-A1AS-01A-11D-A12Q-09 TCGA-AR-A1AS-10A-01D-A12Q-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 3f26f93c-e11a-4ec9-b73b-98fcadc209f4 97a055bf-af49-4c79-bc12-0b3644f21638 1 153043220 153043220 G T SNP SPRR2B ENST00000341611 human ensembl 69_37n -1 known nonsense c.96 p.C32* 0.151 NULL NULL - no_errors SPRR2B HGNC ENSG00000196805 249 0 0.00 149 47 23.98 - - - SPTA1 0 genome.wustl.edu 37 1 158605731 158605733 + In_Frame_Del DEL CCC CCC - TCGA-AR-A1AS-01A-11D-A12Q-09 TCGA-AR-A1AS-10A-01D-A12Q-09 CCC CCC Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 3f26f93c-e11a-4ec9-b73b-98fcadc209f4 97a055bf-af49-4c79-bc12-0b3644f21638 1 158605731 158605733 CCC - DEL SPTA1 ENST00000368148 human ensembl 69_37n -1 known in_frame_del c.5404_5402 p.WEKLK1801in_frame_del* 1.000:1.000:1.000 pfam_Spectrin_repeat,smart_Spectrin/alpha-actinin pfam_Spectrin_repeat,pfam_EF-hand_Ca_insen,pfam_SH3_domain,pfam_SH3_2,superfamily_SH3_domain,smart_Spectrin/alpha-actinin,smart_SH3_domain,pfscan_EF_HAND_2,pfscan_SH3_domain,prints_Spectrin_alpha_SH3 - no_errors SPTA1 HGNC ENSG00000163554 108 0 0.00 84 10 10.53 - - - THEM5 0 genome.wustl.edu 37 1 151819737 151819738 + Frame_Shift_Del DEL GG GG - TCGA-AR-A1AS-01A-11D-A12Q-09 TCGA-AR-A1AS-10A-01D-A12Q-09 GG GG Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 3f26f93c-e11a-4ec9-b73b-98fcadc209f4 97a055bf-af49-4c79-bc12-0b3644f21638 1 151819737 151819738 GG - DEL THEM5 ENST00000453881 human ensembl 69_37n -1 known frame_shift_del c.642_641 p.P214fs 0.878:0.888 NULL pfam_Thioestr_supf - no_start_codon:pseudogene:no_stop_codon:bad_bp_length_for_coding_region THEM5 HGNC ENSG00000196407 8 0 0.00 7 4 33.33 - - - TOMM40 0 genome.wustl.edu 37 19 45406420 45406420 + Silent SNP C C T TCGA-AR-A1AS-01A-11D-A12Q-09 TCGA-AR-A1AS-10A-01D-A12Q-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 3f26f93c-e11a-4ec9-b73b-98fcadc209f4 97a055bf-af49-4c79-bc12-0b3644f21638 19 45406420 45406420 C T SNP TOMM40 ENST00000252487 human ensembl 69_37n +1 known silent c.1080 p.I360 0.916 NULL pfam_Porin_Euk - no_errors TOMM40 HGNC ENSG00000130204 38 0 0.00 36 5 12.20 - - - TP53 0 genome.wustl.edu 37 17 7578406 7578406 + Missense_Mutation SNP C C T TCGA-AR-A1AS-01A-11D-A12Q-09 TCGA-AR-A1AS-10A-01D-A12Q-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 3f26f93c-e11a-4ec9-b73b-98fcadc209f4 97a055bf-af49-4c79-bc12-0b3644f21638 17 7578406 7578406 C T SNP TP53 ENST00000269305 human ensembl 69_37n -1 known missense c.524 p.R175H 1.000 pfam_p53_DNA-bd,superfamily_p53-like_TF_DNA-bd,prints_p53_tumour_suppressor pfam_p53_DNA-bd,pfam_p53_tetrameristn,pfam_p53_transactivation_domain,superfamily_p53-like_TF_DNA-bd,superfamily_p53_tetrameristn,prints_p53_tumour_suppressor - no_errors TP53 HGNC ENSG00000141510 73 0 0.00 20 22 52.38 - - - TTN 0 genome.wustl.edu 37 2 179427821 179427821 + Missense_Mutation SNP C C T TCGA-AR-A1AS-01A-11D-A12Q-09 TCGA-AR-A1AS-10A-01D-A12Q-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 3f26f93c-e11a-4ec9-b73b-98fcadc209f4 97a055bf-af49-4c79-bc12-0b3644f21638 2 179427821 179427821 C T SNP TTN ENST00000342992 human ensembl 69_37n -1 known missense c.75334 p.D25112N 1.000 superfamily_Calpain_domain_III,superfamily_RNaseH-like_dom,smart_Ig_sub,pfscan_Ig-like pfam_Ig_I-set,pfam_Fibronectin_type3,pfam_Immunoglobulin,pfam_Ig_V-set,pfam_Titin_Z,pfam_PPAK_motif,pfam_Prot_kinase_cat_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,superfamily_Fibronectin_type3,superfamily_Calpain_domain_III,superfamily_RNaseH-like_dom,smart_Ig_sub,smart_Ig_sub2,smart_Ig_V-set_subgr,smart_Fibronectin_type3,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Fibronectin_type3,pfscan_Prot_kinase_cat_dom,pfscan_Ig-like - no_errors TTN HGNC ENSG00000155657 99 1 0.99 33 23 41.07 - - - TXNDC2 0 genome.wustl.edu 37 18 9887689 9887689 + Missense_Mutation SNP C C T TCGA-AR-A1AS-01A-11D-A12Q-09 TCGA-AR-A1AS-10A-01D-A12Q-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 3f26f93c-e11a-4ec9-b73b-98fcadc209f4 97a055bf-af49-4c79-bc12-0b3644f21638 18 9887689 9887689 C T SNP TXNDC2 ENST00000306084 human ensembl 69_37n +1 known missense c.1213 p.P405S 0.000 NULL pfam_Thioredoxin_domain,pfam_Glutenin,superfamily_Thioredoxin-like_fold - no_errors TXNDC2 HGNC ENSG00000168454 464 1 0.21 119 73 38.02 - - - WRAP73 0 genome.wustl.edu 37 1 3566551 3566551 + Missense_Mutation SNP C C T TCGA-AR-A1AS-01A-11D-A12Q-09 TCGA-AR-A1AS-10A-01D-A12Q-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 3f26f93c-e11a-4ec9-b73b-98fcadc209f4 97a055bf-af49-4c79-bc12-0b3644f21638 1 3566551 3566551 C T SNP WRAP73 ENST00000270708 human ensembl 69_37n -1 known missense c.13 p.E5K 1.000 NULL pfam_WD40_repeat,superfamily_WD40_repeat_dom,smart_WD40_repeat - no_errors WRAP73 HGNC ENSG00000116213 14 0 0.00 9 4 30.77 - - - ZC3H11A 0 genome.wustl.edu 37 1 203819082 203819082 + Missense_Mutation SNP G G A TCGA-AR-A1AS-01A-11D-A12Q-09 TCGA-AR-A1AS-10A-01D-A12Q-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 3f26f93c-e11a-4ec9-b73b-98fcadc209f4 97a055bf-af49-4c79-bc12-0b3644f21638 1 203819082 203819082 G A SNP ZC3H11A ENST00000332127 human ensembl 69_37n +1 known missense c.1867 p.E623K 0.989 NULL smart_Znf_CCCH - no_errors ZC3H11A HGNC ENSG00000058673 74 0 0.00 42 9 17.65 - - -