Hugo_Symbol Entrez_Gene_Id Center NCBI_Build Chromosome Start_Position End_Position Strand Variant_Classification Variant_Type Reference_Allele Tumor_Seq_Allele1 Tumor_Seq_Allele2 dbSNP_RS dbSNP_Val_Status Tumor_Sample_Barcode Matched_Norm_Sample_Barcode Match_Norm_Seq_Allele1 Match_Norm_Seq_Allele2 Tumor_Validation_Allele1 Tumor_Validation_Allele2 Match_Norm_Validation_Allele1 Match_Norm_Validation_Allele2 Verification_Status Validation_Status Mutation_Status Sequencing_Phase Sequence_Source Validation_Method Score BAM_File Sequencer Tumor_Sample_UUID Matched_Norm_Sample_UUID chromosome_name_WU start_WU stop_WU reference_WU variant_WU type_WU gene_name_WU transcript_name_WU transcript_species_WU transcript_source_WU transcript_version_WU strand_WU transcript_status_WU trv_type_WU c_position_WU amino_acid_change_WU ucsc_cons_WU domain_WU all_domains_WU deletion_substructures_WU transcript_error_WU default_gene_name_WU gene_name_source_WU ensembl_gene_id normal_ref_reads normal_var_reads normal_vaf tumor_ref_reads tumors_var_reads tumor_vaf EVS_EA EVS_AA EVS_All ADAR 0 genome.wustl.edu 37 1 154557805 154557805 + Missense_Mutation SNP T T G TCGA-AR-A24R-01A-11D-A167-09 TCGA-AR-A24R-10A-01D-A167-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx baf43433-0001-4495-a37f-9132eb213157 b45104f7-fe20-40de-ae99-af24c080a284 1 154557805 154557805 T G SNP ADAR ENST00000292205 human ensembl 69_37n -1 known missense c.3460 p.I1154L 1.000 pfam_A_deamin,smart_A_deamin,pfscan_A_deamin pfam_A_deamin,pfam_dsRNA_A_deaminase,pfam_Ds-RNA-bd,smart_dsRNA_A_deaminase,smart_Ds-RNA-bd,smart_A_deamin,pfscan_Ds-RNA-bd,pfscan_dsRNA_A_deaminase,pfscan_A_deamin - no_errors ADAR HGNC ENSG00000160710 44 0 0.00 46 21 31.34 - - - APPL2 0 genome.wustl.edu 37 12 105589107 105589107 + Missense_Mutation SNP A A C TCGA-AR-A24R-01A-11D-A167-09 TCGA-AR-A24R-10A-01D-A167-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx baf43433-0001-4495-a37f-9132eb213157 b45104f7-fe20-40de-ae99-af24c080a284 12 105589107 105589107 A C SNP APPL2 ENST00000551662 human ensembl 69_37n -1 known missense c.1191 p.N397K 0.998 NULL pfam_PTyr_interaction_dom,pfam_Pleckstrin_homology,pfam_PTB,smart_Pleckstrin_homology,smart_PTyr_interaction_dom,pfscan_Pleckstrin_homology,pfscan_PTyr_interaction_dom - no_errors APPL2 HGNC ENSG00000136044 80 0 0.00 52 17 24.64 - - - ARHGEF38 0 genome.wustl.edu 37 4 106552056 106552058 + In_Frame_Del DEL AGA AGA - TCGA-AR-A24R-01A-11D-A167-09 TCGA-AR-A24R-10A-01D-A167-09 AGA AGA Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx baf43433-0001-4495-a37f-9132eb213157 b45104f7-fe20-40de-ae99-af24c080a284 4 106552056 106552058 AGA - DEL ARHGEF38 ENST00000265154 human ensembl 69_37n +1 known in_frame_del c.510_512 p.E171in_frame_del 0.987:1.000:1.000 pfam_DH-domain,superfamily_DH-domain,pfscan_DH-domain pfam_DH-domain,superfamily_DH-domain,pfscan_DH-domain - no_errors ARHGEF38 HGNC ENSG00000236699 61 0 0.00 43 11 20.37 - - - CHUK 0 genome.wustl.edu 37 10 101978864 101978864 + Missense_Mutation SNP G G A TCGA-AR-A24R-01A-11D-A167-09 TCGA-AR-A24R-10A-01D-A167-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx baf43433-0001-4495-a37f-9132eb213157 b45104f7-fe20-40de-ae99-af24c080a284 10 101978864 101978864 G A SNP CHUK ENST00000370397 human ensembl 69_37n -1 known missense c.590 p.P197L 1.000 pfam_Prot_kinase_cat_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_cat_dom pfam_Prot_kinase_cat_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_IKKbetaNEMObind,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_cat_dom,prints_Ser-Thr/Tyr_kinase_cat_dom - no_errors CHUK HGNC ENSG00000213341 49 0 0.00 25 27 51.92 - - - CNPY3 0 genome.wustl.edu 37 6 42897358 42897360 + In_Frame_Del DEL TGC TGC - TCGA-AR-A24R-01A-11D-A167-09 TCGA-AR-A24R-10A-01D-A167-09 TGC TGC Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx baf43433-0001-4495-a37f-9132eb213157 b45104f7-fe20-40de-ae99-af24c080a284 6 42897358 42897360 TGC - DEL CNPY3 ENST00000372836 human ensembl 69_37n +1 known in_frame_del c.50_52 p.L21in_frame_del 0.122:0.131:0.153 NULL pfam_DUF3456 - no_errors CNPY3 HGNC ENSG00000137161 10 0 0.00 4 2 33.33 - - - CXorf65 0 genome.wustl.edu 37 X 70325861 70325861 + Missense_Mutation SNP C C T TCGA-AR-A24R-01A-11D-A167-09 TCGA-AR-A24R-10A-01D-A167-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx baf43433-0001-4495-a37f-9132eb213157 b45104f7-fe20-40de-ae99-af24c080a284 X 70325861 70325861 C T SNP CXorf65 ENST00000374251 human ensembl 69_37n -1 known missense c.239 p.R80H 0.812 NULL NULL - no_errors CXorf65 HGNC ENSG00000204165 64 0 0.00 40 21 34.43 - - - DGKB 0 genome.wustl.edu 37 7 14737756 14737756 + Silent SNP T T C TCGA-AR-A24R-01A-11D-A167-09 TCGA-AR-A24R-10A-01D-A167-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx baf43433-0001-4495-a37f-9132eb213157 b45104f7-fe20-40de-ae99-af24c080a284 7 14737756 14737756 T C SNP DGKB ENST00000258767 human ensembl 69_37n -1 known silent c.555 p.A185 0.996 NULL pfam_Diacylglycerol_kin_accessory,pfam_Diacylglycerol_kinase_cat_dom,pfam_Prot_Kinase_C-like_PE/DAG-bd,smart_EF_hand_Ca-bd,smart_Prot_Kinase_C-like_PE/DAG-bd,smart_Diacylglycerol_kinase_cat_dom,smart_Diacylglycerol_kin_accessory,pfscan_EF_HAND_2,pfscan_Prot_Kinase_C-like_PE/DAG-bd - no_errors DGKB HGNC ENSG00000136267 60 0 0.00 31 22 41.51 - - - DNAI2 0 genome.wustl.edu 37 17 72310298 72310298 + Missense_Mutation SNP G G A TCGA-AR-A24R-01A-11D-A167-09 TCGA-AR-A24R-10A-01D-A167-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx baf43433-0001-4495-a37f-9132eb213157 b45104f7-fe20-40de-ae99-af24c080a284 17 72310298 72310298 G A SNP DNAI2 ENST00000307504 human ensembl 69_37n +1 known missense c.1177 p.G393R 0.000 NULL pfam_WD40_repeat,superfamily_WD40_repeat_dom,smart_WD40_repeat,pfscan_WD40_repeat_dom - no_errors DNAI2 HGNC ENSG00000171595 72 0 0.00 78 15 16.13 - - - GDAP1 0 genome.wustl.edu 37 8 75263607 75263607 + Silent SNP C C T TCGA-AR-A24R-01A-11D-A167-09 TCGA-AR-A24R-10A-01D-A167-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx baf43433-0001-4495-a37f-9132eb213157 b45104f7-fe20-40de-ae99-af24c080a284 8 75263607 75263607 C T SNP GDAP1 ENST00000220822 human ensembl 69_37n +1 known silent c.216 p.N72 1.000 pfam_Glutathione_S-Trfase_N,superfamily_Thioredoxin-like_fold pfam_Glutathione_S-Trfase_N,pfam_GST_C,superfamily_Thioredoxin-like_fold,superfamily_Glutathione-S-Trfase_C-like - no_errors GDAP1 HGNC ENSG00000104381 81 0 0.00 92 28 23.33 - - - INPP5B 0 genome.wustl.edu 37 1 38341357 38341357 + Missense_Mutation SNP T T A TCGA-AR-A24R-01A-11D-A167-09 TCGA-AR-A24R-10A-01D-A167-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx baf43433-0001-4495-a37f-9132eb213157 b45104f7-fe20-40de-ae99-af24c080a284 1 38341357 38341357 T A SNP INPP5B ENST00000373023 human ensembl 69_37n -1 known missense c.1949 p.K650M 1.000 superfamily_Endo/exonuclease/phosphatase pfam_Endo/exonuclease/phosphatase,pfam_RhoGAP_dom,superfamily_Endo/exonuclease/phosphatase,superfamily_Rho_GTPase_activation_prot,smart_IPPc,smart_RhoGAP_dom,pfscan_RhoGAP_dom - no_errors INPP5B HGNC ENSG00000204084 41 0 0.00 11 15 57.69 - - - LETM1 0 genome.wustl.edu 37 4 1818540 1818540 + Missense_Mutation SNP C C T TCGA-AR-A24R-01A-11D-A167-09 TCGA-AR-A24R-10A-01D-A167-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx baf43433-0001-4495-a37f-9132eb213157 b45104f7-fe20-40de-ae99-af24c080a284 4 1818540 1818540 C T SNP LETM1 ENST00000302787 human ensembl 69_37n -1 known missense c.1845 p.M615I 1.000 NULL pfam_LETM1,pfscan_EF_HAND_2 - no_errors LETM1 HGNC ENSG00000168924 79 0 0.00 61 22 26.51 - - - MLLT4 0 genome.wustl.edu 37 6 168323655 168323655 + Missense_Mutation SNP G G T TCGA-AR-A24R-01A-11D-A167-09 TCGA-AR-A24R-10A-01D-A167-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx baf43433-0001-4495-a37f-9132eb213157 b45104f7-fe20-40de-ae99-af24c080a284 6 168323655 168323655 G T SNP MLLT4 ENST00000497596 human ensembl 69_37n +1 putative missense c.496 p.V166L 0.000 NULL pfam_Dil_domain,pfscan_Dilute - no_start_codon MLLT4 HGNC ENSG00000130396 48 0 0.00 11 11 50.00 - - - OR4N5 0 genome.wustl.edu 37 14 20612744 20612744 + Missense_Mutation SNP C C T TCGA-AR-A24R-01A-11D-A167-09 TCGA-AR-A24R-10A-01D-A167-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx baf43433-0001-4495-a37f-9132eb213157 b45104f7-fe20-40de-ae99-af24c080a284 14 20612744 20612744 C T SNP OR4N5 ENST00000333629 human ensembl 69_37n +1 known missense c.850 p.P284S 1.000 pfam_7TM_GPCR_Rhodpsn,prints_Olfact_rcpt,prints_7TM_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_supfam pfam_7TM_GPCR_Rhodpsn,prints_Olfact_rcpt,prints_7TM_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_supfam - no_errors OR4N5 HGNC ENSG00000184394 35 0 0.00 38 17 30.91 - - - OR5C1 0 genome.wustl.edu 37 9 125551282 125551282 + Missense_Mutation SNP G G A TCGA-AR-A24R-01A-11D-A167-09 TCGA-AR-A24R-10A-01D-A167-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx baf43433-0001-4495-a37f-9132eb213157 b45104f7-fe20-40de-ae99-af24c080a284 9 125551282 125551282 G A SNP OR5C1 ENST00000373680 human ensembl 69_37n +1 known missense c.71 p.R24H 0.001 NULL pfam_7TM_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_supfam,prints_Olfact_rcpt,prints_7TM_GPCR_Rhodpsn - no_errors OR5C1 HGNC ENSG00000148215 58 0 0.00 18 20 51.28 - - - PIGW 0 genome.wustl.edu 37 17 34894403 34894403 + Missense_Mutation SNP T T C TCGA-AR-A24R-01A-11D-A167-09 TCGA-AR-A24R-10A-01D-A167-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx baf43433-0001-4495-a37f-9132eb213157 b45104f7-fe20-40de-ae99-af24c080a284 17 34894403 34894403 T C SNP PIGW ENST00000328396 human ensembl 69_37n +1 known missense c.1453 p.F485L 0.997 pirsf_GWT1 pfam_GWT1,pirsf_GWT1 - no_errors PIGW HGNC ENSG00000184886 18 0 0.00 15 7 31.82 - - - REXO1 0 genome.wustl.edu 37 19 1825883 1825883 + Silent SNP G G A TCGA-AR-A24R-01A-11D-A167-09 TCGA-AR-A24R-10A-01D-A167-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx baf43433-0001-4495-a37f-9132eb213157 b45104f7-fe20-40de-ae99-af24c080a284 19 1825883 1825883 G A SNP REXO1 ENST00000170168 human ensembl 69_37n -1 known silent c.1971 p.P657 0.862 NULL pfam_Exonuclease_RNaseT/DNA_pol3,superfamily_RNaseH-like_dom,smart_Exonuclease - no_errors REXO1 HGNC ENSG00000079313 40 0 0.00 24 13 35.14 - - - RUNX1 0 genome.wustl.edu 37 21 36171623 36171624 + Frame_Shift_Del DEL AG AG - TCGA-AR-A24R-01A-11D-A167-09 TCGA-AR-A24R-10A-01D-A167-09 AG AG Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx baf43433-0001-4495-a37f-9132eb213157 b45104f7-fe20-40de-ae99-af24c080a284 21 36171623 36171624 AG - DEL RUNX1 ENST00000300305 human ensembl 69_37n -1 known frame_shift_del c.942_941 p.S314fs 0.839:0.999 pirsf_TF_Runt-rel_RUNX pfam_AML1/Runt_N,pfam_RunxI,superfamily_p53-like_TF_DNA-bd,pirsf_TF_Runt-rel_RUNX,pfscan_AML1/Runt_N,prints_AML1_Runt - no_errors RUNX1 HGNC ENSG00000159216 66 0 0.00 41 30 41.67 - - - SUPT5H 0 genome.wustl.edu 37 19 39959953 39959953 + Missense_Mutation SNP A A C TCGA-AR-A24R-01A-11D-A167-09 TCGA-AR-A24R-10A-01D-A167-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx baf43433-0001-4495-a37f-9132eb213157 b45104f7-fe20-40de-ae99-af24c080a284 19 39959953 39959953 A C SNP SUPT5H ENST00000359191 human ensembl 69_37n +1 known missense c.1289 p.E430A 1.000 superfamily_Translation_prot_SH3-like,smart_KOW,pirsf_TF_Spt5 pfam_TF_Spt5_NGN-domain,pfam_KOW,pfam_Spt5_N,superfamily_Translation_prot_SH3-like,smart_Transcrpt_antiterm_NusG_N,smart_KOW,pirsf_TF_Spt5 - no_errors SUPT5H HGNC ENSG00000196235 38 0 0.00 8 8 50.00 - - - THOP1 0 genome.wustl.edu 37 19 2807034 2807034 + Silent SNP C C T TCGA-AR-A24R-01A-11D-A167-09 TCGA-AR-A24R-10A-01D-A167-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx baf43433-0001-4495-a37f-9132eb213157 b45104f7-fe20-40de-ae99-af24c080a284 19 2807034 2807034 C T SNP THOP1 ENST00000307741 human ensembl 69_37n +1 known silent c.870 p.T290 0.152 pfam_Pept_M3A_M3B pfam_Pept_M3A_M3B - no_errors THOP1 HGNC ENSG00000172009 48 0 0.00 17 6 26.09 - - - TMED10 0 genome.wustl.edu 37 14 75643124 75643124 + Frame_Shift_Del DEL T T - TCGA-AR-A24R-01A-11D-A167-09 TCGA-AR-A24R-10A-01D-A167-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx baf43433-0001-4495-a37f-9132eb213157 b45104f7-fe20-40de-ae99-af24c080a284 14 75643124 75643124 T - DEL TMED10 ENST00000303575 human ensembl 69_37n -1 known frame_shift_del c.159 p.V54fs 0.998 pfam_GOLD,pfscan_GOLD pfam_GOLD,pfscan_GOLD - no_errors TMED10 HGNC ENSG00000170348 17 0 0.00 11 5 31.25 - - - TMED10 0 genome.wustl.edu 37 14 75643142 75643145 + Frame_Shift_Del DEL CTCC CTCC - TCGA-AR-A24R-01A-11D-A167-09 TCGA-AR-A24R-10A-01D-A167-09 CTCC CTCC Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx baf43433-0001-4495-a37f-9132eb213157 b45104f7-fe20-40de-ae99-af24c080a284 14 75643142 75643145 CTCC - DEL TMED10 ENST00000303575 human ensembl 69_37n -1 known frame_shift_del c.141_138 p.E47fs 1.000:1.000:1.000:1.000 pfam_GOLD,pfscan_GOLD pfam_GOLD,pfscan_GOLD - no_errors TMED10 HGNC ENSG00000170348 20 0 0.00 15 5 25.00 - - - TTLL5 0 genome.wustl.edu 37 14 76187037 76187037 + Missense_Mutation SNP A A G TCGA-AR-A24R-01A-11D-A167-09 TCGA-AR-A24R-10A-01D-A167-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx baf43433-0001-4495-a37f-9132eb213157 b45104f7-fe20-40de-ae99-af24c080a284 14 76187037 76187037 A G SNP TTLL5 ENST00000298832 human ensembl 69_37n +1 known missense c.1033 p.S345G 1.000 pfam_Tub_tyr_ligase pfam_Tub_tyr_ligase - no_errors TTLL5 HGNC ENSG00000119685 62 0 0.00 49 30 37.97 - - - VWA3B 0 genome.wustl.edu 37 2 98928335 98928335 + Missense_Mutation SNP C C T TCGA-AR-A24R-01A-11D-A167-09 TCGA-AR-A24R-10A-01D-A167-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx baf43433-0001-4495-a37f-9132eb213157 b45104f7-fe20-40de-ae99-af24c080a284 2 98928335 98928335 C T SNP VWA3B ENST00000477737 human ensembl 69_37n +1 known missense c.3575 p.A1192V 0.000 NULL pfam_VWF_A,smart_VWF_A,pfscan_VWF_A - no_errors VWA3B HGNC ENSG00000168658 20 0 0.00 13 7 31.82 - - - WASH3P 0 genome.wustl.edu 37 15 102516539 102516539 + RNA SNP C C G TCGA-AR-A24R-01A-11D-A167-09 TCGA-AR-A24R-10A-01D-A167-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx baf43433-0001-4495-a37f-9132eb213157 b45104f7-fe20-40de-ae99-af24c080a284 15 102516539 102516539 C G SNP WASH3P ENST00000557932 human ensembl 69_37n +1 known rna NULL NULL 0.000 - - - no_errors WASH3P HGNC ENSG00000185596 12 0 0.00 3 3 50.00 - - - WDFY3 0 genome.wustl.edu 37 4 85731339 85731339 + Frame_Shift_Del DEL A A - TCGA-AR-A24R-01A-11D-A167-09 TCGA-AR-A24R-10A-01D-A167-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx baf43433-0001-4495-a37f-9132eb213157 b45104f7-fe20-40de-ae99-af24c080a284 4 85731339 85731339 A - DEL WDFY3 ENST00000295888 human ensembl 69_37n -1 known frame_shift_del c.2046 p.F682fs 0.993 superfamily_ARM-type_fold pfam_BEACH_dom,pfam_Znf_FYVE,pfam_WD40_repeat,superfamily_BEACH_dom,superfamily_WD40_repeat_dom,superfamily_Znf_FYVE_PHD,superfamily_ConA-like_lec_gl,superfamily_Cyclin-like,superfamily_ARM-type_fold,smart_WD40_repeat,smart_Znf_FYVE,pfscan_BEACH_dom,pfscan_Znf_FYVE-rel,pfscan_WD40_repeat,pfscan_WD40_repeat_dom - no_errors WDFY3 HGNC ENSG00000163625 42 0 0.00 26 14 35.00 - - - ZDHHC22 0 genome.wustl.edu 37 14 77600207 77600207 + Missense_Mutation SNP C C T TCGA-AR-A24R-01A-11D-A167-09 TCGA-AR-A24R-10A-01D-A167-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx baf43433-0001-4495-a37f-9132eb213157 b45104f7-fe20-40de-ae99-af24c080a284 14 77600207 77600207 C T SNP ZDHHC22 ENST00000319374 human ensembl 69_37n -1 known missense c.611 p.C204Y 1.000 NULL pfam_Znf_DHHC_palmitoyltrfase,pfscan_SSD,pfscan_Znf_DHHC_palmitoyltrfase - no_errors ZDHHC22 HGNC ENSG00000177108 28 0 0.00 14 9 39.13 - - -