Hugo_Symbol Entrez_Gene_Id Center NCBI_Build Chromosome Start_Position End_Position Strand Variant_Classification Variant_Type Reference_Allele Tumor_Seq_Allele1 Tumor_Seq_Allele2 dbSNP_RS dbSNP_Val_Status Tumor_Sample_Barcode Matched_Norm_Sample_Barcode Match_Norm_Seq_Allele1 Match_Norm_Seq_Allele2 Tumor_Validation_Allele1 Tumor_Validation_Allele2 Match_Norm_Validation_Allele1 Match_Norm_Validation_Allele2 Verification_Status Validation_Status Mutation_Status Sequencing_Phase Sequence_Source Validation_Method Score BAM_File Sequencer Tumor_Sample_UUID Matched_Norm_Sample_UUID chromosome_name_WU start_WU stop_WU reference_WU variant_WU type_WU gene_name_WU transcript_name_WU transcript_species_WU transcript_source_WU transcript_version_WU strand_WU transcript_status_WU trv_type_WU c_position_WU amino_acid_change_WU ucsc_cons_WU domain_WU all_domains_WU deletion_substructures_WU transcript_error_WU default_gene_name_WU gene_name_source_WU ensembl_gene_id normal_ref_reads normal_var_reads normal_vaf tumor_ref_reads tumors_var_reads tumor_vaf EVS_EA EVS_AA EVS_All ABCA9 0 genome.wustl.edu 37 17 67029972 67029972 + Missense_Mutation SNP C C A TCGA-AR-A2LL-01A-11D-A17W-09 TCGA-AR-A2LL-10A-01D-A17W-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9b2fb8e3-62a1-45b0-9d8d-c2b2e9d392ee 2db1c6af-2da9-4408-b5cf-b1f0e65ec6e0 17 67029972 67029972 C A SNP ABCA9 ENST00000340001 human ensembl 69_37n -1 known missense c.1171 p.D391Y 0.003 NULL pfam_ABC_transporter-like,smart_AAA+_ATPase,pfscan_ABC_transporter-like - no_errors ABCA9 HGNC ENSG00000154258 58 0 0.00 88 26 22.81 - - - C14orf105 0 genome.wustl.edu 37 14 57949847 57949847 + Missense_Mutation SNP G G T TCGA-AR-A2LL-01A-11D-A17W-09 TCGA-AR-A2LL-10A-01D-A17W-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9b2fb8e3-62a1-45b0-9d8d-c2b2e9d392ee 2db1c6af-2da9-4408-b5cf-b1f0e65ec6e0 14 57949847 57949847 G T SNP C14orf105 ENST00000216445 human ensembl 69_37n -1 known missense c.329 p.P110Q 1.000 NULL NULL - no_errors C14orf105 HGNC ENSG00000100557 80 0 0.00 91 33 26.61 - - - CD48 0 genome.wustl.edu 37 1 160654790 160654790 + Missense_Mutation SNP C C T TCGA-AR-A2LL-01A-11D-A17W-09 TCGA-AR-A2LL-10A-01D-A17W-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9b2fb8e3-62a1-45b0-9d8d-c2b2e9d392ee 2db1c6af-2da9-4408-b5cf-b1f0e65ec6e0 1 160654790 160654790 C T SNP CD48 ENST00000368046 human ensembl 69_37n -1 known missense c.272 p.S91N 0.000 pfam_Ig_V-set,smart_Ig_sub pfam_Ig_V-set,smart_Ig_sub,pfscan_Ig-like - no_errors CD48 HGNC ENSG00000117091 46 0 0.00 95 55 36.67 - - - CDH1 0 genome.wustl.edu 37 16 68844244 68844244 + Missense_Mutation SNP G G A TCGA-AR-A2LL-01A-11D-A17W-09 TCGA-AR-A2LL-10A-01D-A17W-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9b2fb8e3-62a1-45b0-9d8d-c2b2e9d392ee 2db1c6af-2da9-4408-b5cf-b1f0e65ec6e0 16 68844244 68844244 G A SNP CDH1 ENST00000261769 human ensembl 69_37n +1 known missense c.832 p.G278R 1.000 pfam_Cadherin,superfamily_Cadherin-like,pfscan_Cadherin,prints_Cadherin pfam_Cadherin,pfam_Cadherin_cytoplasmic-dom,pfam_Cadherin_pro_dom,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin,prints_Cadherin - no_errors CDH1 HGNC ENSG00000039068 43 0 0.00 17 11 39.29 - - - CLNK 0 genome.wustl.edu 37 4 10515108 10515108 + Missense_Mutation SNP G G T TCGA-AR-A2LL-01A-11D-A17W-09 TCGA-AR-A2LL-10A-01D-A17W-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9b2fb8e3-62a1-45b0-9d8d-c2b2e9d392ee 2db1c6af-2da9-4408-b5cf-b1f0e65ec6e0 4 10515108 10515108 G T SNP CLNK ENST00000226951 human ensembl 69_37n -1 known missense c.886 p.P296T 0.120 NULL pfam_SH2,smart_SH2,prints_SH2,pfscan_SH2 - no_errors CLNK HGNC ENSG00000109684 61 0 0.00 58 58 50.00 - - - CSNK1G2 0 genome.wustl.edu 37 19 1978327 1978327 + Missense_Mutation SNP T T C TCGA-AR-A2LL-01A-11D-A17W-09 TCGA-AR-A2LL-10A-01D-A17W-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9b2fb8e3-62a1-45b0-9d8d-c2b2e9d392ee 2db1c6af-2da9-4408-b5cf-b1f0e65ec6e0 19 1978327 1978327 T C SNP CSNK1G2 ENST00000255641 human ensembl 69_37n +1 known missense c.211 p.Y71H 1.000 pfam_Prot_kinase_cat_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_cat_dom pfam_Prot_kinase_cat_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Casein_kinase-1_gamma_C,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_cat_dom - no_errors CSNK1G2 HGNC ENSG00000133275 22 0 0.00 25 8 24.24 - - - EPHA2 0 genome.wustl.edu 37 1 16464648 16464648 + Missense_Mutation SNP C C T TCGA-AR-A2LL-01A-11D-A17W-09 TCGA-AR-A2LL-10A-01D-A17W-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9b2fb8e3-62a1-45b0-9d8d-c2b2e9d392ee 2db1c6af-2da9-4408-b5cf-b1f0e65ec6e0 1 16464648 16464648 C T SNP EPHA2 ENST00000358432 human ensembl 69_37n -1 known missense c.1012 p.V338M 0.166 pirsf_Tyr_kinase_ephrin_rcpt,pfam_Fibronectin_type3,superfamily_Fibronectin_type3,smart_Fibronectin_type3,pfscan_Fibronectin_type3 pirsf_Tyr_kinase_ephrin_rcpt,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Ephrin_rcpt_lig-bd_dom,pfam_Prot_kinase_cat_dom,pfam_Fibronectin_type3,pfam_SAM_type1,pfam_SAM_2,pfam_Interferon_alpha/beta_rcpt_bsu,superfamily_Galactose-bd-like,superfamily_Kinase-like_dom,superfamily_Fibronectin_type3,superfamily_SAM/pointed,superfamily_Growth_fac_rcpt,smart_Ephrin_rcpt_lig-bd_dom,smart_Fibronectin_type3,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,smart_SAM,prints_Ser-Thr/Tyr_kinase_cat_dom,pfscan_Fibronectin_type3,pfscan_SAM,pfscan_Prot_kinase_cat_dom - no_errors EPHA2 HGNC ENSG00000142627 10 0 0.00 10 5 33.33 - - - FCGBP 0 genome.wustl.edu 37 19 40377034 40377034 + Silent SNP G G A TCGA-AR-A2LL-01A-11D-A17W-09 TCGA-AR-A2LL-10A-01D-A17W-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9b2fb8e3-62a1-45b0-9d8d-c2b2e9d392ee 2db1c6af-2da9-4408-b5cf-b1f0e65ec6e0 19 40377034 40377034 G A SNP FCGBP ENST00000221347 human ensembl 69_37n -1 known silent c.11388 p.N3796 0.470 pfam_VWF_type-D,smart_VWF_type-D pfam_VWF_type-D,pfam_Unchr_dom_Cys-rich,pfam_TIL_dom,superfamily_TIL_dom,smart_Fol_N,smart_VWF_type-D,smart_Unchr_dom_Cys-rich,smart_EGF-like,smart_VWF_C,smart_VWC_out - no_errors FCGBP HGNC ENSG00000090920 21 0 0.00 31 6 16.22 - - - FKTN 0 genome.wustl.edu 37 9 108380351 108380351 + Missense_Mutation SNP C C T TCGA-AR-A2LL-01A-11D-A17W-09 TCGA-AR-A2LL-10A-01D-A17W-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9b2fb8e3-62a1-45b0-9d8d-c2b2e9d392ee 2db1c6af-2da9-4408-b5cf-b1f0e65ec6e0 9 108380351 108380351 C T SNP FKTN ENST00000223528 human ensembl 69_37n +1 known missense c.1022 p.P341L 0.998 pfam_LicD pfam_LicD,superfamily_Hedgehog_sig/DD-Pept_Zn-bd_dom - no_errors FKTN HGNC ENSG00000106692 41 0 0.00 21 6 22.22 - - - FRMD3 0 genome.wustl.edu 37 9 85905548 85905548 + Missense_Mutation SNP C C G TCGA-AR-A2LL-01A-11D-A17W-09 TCGA-AR-A2LL-10A-01D-A17W-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9b2fb8e3-62a1-45b0-9d8d-c2b2e9d392ee 2db1c6af-2da9-4408-b5cf-b1f0e65ec6e0 9 85905548 85905548 C G SNP FRMD3 ENST00000304195 human ensembl 69_37n -1 known missense c.1165 p.E389Q 0.998 NULL pfam_FERM_N,pfam_FERM_PH-like_C,pfam_FERM_central,pfam_FERM-adjacent,superfamily_FERM_central,smart_Band_41_domain,pfscan_FERM_domain,prints_Band_41_fam,prints_Ez/rad/moesin - no_errors FRMD3 HGNC ENSG00000172159 43 0 0.00 57 42 42.42 - - - GRPR 0 genome.wustl.edu 37 X 16170432 16170432 + Silent SNP C C T TCGA-AR-A2LL-01A-11D-A17W-09 TCGA-AR-A2LL-10A-01D-A17W-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9b2fb8e3-62a1-45b0-9d8d-c2b2e9d392ee 2db1c6af-2da9-4408-b5cf-b1f0e65ec6e0 X 16170432 16170432 C T SNP GRPR ENST00000380289 human ensembl 69_37n +1 known silent c.819 p.F273 0.843 pfam_7TM_GPCR_Rhodpsn,pfam_7TM_GPCR_serpentine_rcpt_Srv,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_supfam,prints_7TM_GPCR_Rhodpsn pfam_7TM_GPCR_Rhodpsn,pfam_7TM_GPCR_serpentine_rcpt_Srv,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_supfam,prints_Bombsn_rcpt,prints_Gastrin_pep_rcpt,prints_7TM_GPCR_Rhodpsn,prints_NPY_rcpt - no_errors GRPR HGNC ENSG00000126010 38 0 0.00 22 12 35.29 - - - HERC6 0 genome.wustl.edu 37 4 89338639 89338639 + Missense_Mutation SNP G G A TCGA-AR-A2LL-01A-11D-A17W-09 TCGA-AR-A2LL-10A-01D-A17W-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9b2fb8e3-62a1-45b0-9d8d-c2b2e9d392ee 2db1c6af-2da9-4408-b5cf-b1f0e65ec6e0 4 89338639 89338639 G A SNP HERC6 ENST00000264346 human ensembl 69_37n +1 known missense c.1621 p.A541T 0.012 NULL pfam_HECT,pfam_Reg_chr_condens,superfamily_HECT,superfamily_Reg_csome_cond/b-lactamase_inh,smart_HECT,pfscan_HECT,pfscan_Reg_chr_condens,prints_Reg_chr_condens - no_errors HERC6 HGNC ENSG00000138642 75 0 0.00 83 18 17.82 - - - IL1RAPL2 0 genome.wustl.edu 37 X 105011476 105011476 + Missense_Mutation SNP C C T TCGA-AR-A2LL-01A-11D-A17W-09 TCGA-AR-A2LL-10A-01D-A17W-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9b2fb8e3-62a1-45b0-9d8d-c2b2e9d392ee 2db1c6af-2da9-4408-b5cf-b1f0e65ec6e0 X 105011476 105011476 C T SNP IL1RAPL2 ENST00000344799 human ensembl 69_37n +1 known missense c.1883 p.T628M 0.217 NULL pfam_TIR_dom,superfamily_TIR_dom,smart_Ig_sub,smart_TIR_dom,pfscan_TIR_dom,pfscan_Ig-like,prints_IL1_rcpt_1,prints_Interleukin-1_rcpt_II - no_errors IL1RAPL2 HGNC ENSG00000189108 65 0 0.00 40 22 35.48 - - - IRAK1BP1 0 genome.wustl.edu 37 6 79577396 79577396 + Missense_Mutation SNP C C T TCGA-AR-A2LL-01A-11D-A17W-09 TCGA-AR-A2LL-10A-01D-A17W-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9b2fb8e3-62a1-45b0-9d8d-c2b2e9d392ee 2db1c6af-2da9-4408-b5cf-b1f0e65ec6e0 6 79577396 79577396 C T SNP IRAK1BP1 ENST00000369940 human ensembl 69_37n +1 known missense c.103 p.P35S 0.042 NULL pfam_DUF541 - no_errors IRAK1BP1 HGNC ENSG00000146243 15 0 0.00 17 15 46.88 - - - ITGA6 0 genome.wustl.edu 37 2 173362764 173362764 + Missense_Mutation SNP T T C TCGA-AR-A2LL-01A-11D-A17W-09 TCGA-AR-A2LL-10A-01D-A17W-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9b2fb8e3-62a1-45b0-9d8d-c2b2e9d392ee 2db1c6af-2da9-4408-b5cf-b1f0e65ec6e0 2 173362764 173362764 T C SNP ITGA6 ENST00000264106 human ensembl 69_37n +1 known missense c.3167 p.I1056T 1.000 NULL pfam_Integrin_alpha-2,pfam_FG-GAP,smart_Int_alpha_beta-p,prints_Integrin_alpha - no_errors ITGA6 HGNC ENSG00000091409 177 0 0.00 146 80 35.40 - - - ITGAM 0 genome.wustl.edu 37 16 31282377 31282377 + Missense_Mutation SNP T T C TCGA-AR-A2LL-01A-11D-A17W-09 TCGA-AR-A2LL-10A-01D-A17W-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9b2fb8e3-62a1-45b0-9d8d-c2b2e9d392ee 2db1c6af-2da9-4408-b5cf-b1f0e65ec6e0 16 31282377 31282377 T C SNP ITGAM ENST00000544665 human ensembl 69_37n +1 known missense c.530 p.M177T 1.000 pfam_VWF_A,smart_VWF_A,pfscan_VWF_A pfam_Integrin_alpha-2,pfam_VWF_A,pfam_FG-GAP,pfam_Integrin_alpha_C_CS,smart_Int_alpha_beta-p,smart_VWF_A,pfscan_VWF_A,prints_Integrin_alpha - no_errors ITGAM HGNC ENSG00000169896 56 0 0.00 51 30 37.04 - - - KLF15 0 genome.wustl.edu 37 3 126070862 126070862 + Missense_Mutation SNP C C T TCGA-AR-A2LL-01A-11D-A17W-09 TCGA-AR-A2LL-10A-01D-A17W-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9b2fb8e3-62a1-45b0-9d8d-c2b2e9d392ee 2db1c6af-2da9-4408-b5cf-b1f0e65ec6e0 3 126070862 126070862 C T SNP KLF15 ENST00000296233 human ensembl 69_37n -1 known missense c.904 p.G302S 0.448 NULL pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2 - no_errors KLF15 HGNC ENSG00000163884 53 0 0.00 39 34 46.58 - - - MYO3B 0 genome.wustl.edu 37 2 171509542 171509542 + Missense_Mutation SNP C C T TCGA-AR-A2LL-01A-11D-A17W-09 TCGA-AR-A2LL-10A-01D-A17W-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9b2fb8e3-62a1-45b0-9d8d-c2b2e9d392ee 2db1c6af-2da9-4408-b5cf-b1f0e65ec6e0 2 171509542 171509542 C T SNP MYO3B ENST00000334231 human ensembl 69_37n +1 known missense c.3964 p.P1322S 0.991 NULL pfam_Myosin_head_motor_dom,pfam_Prot_kinase_cat_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_IQ_motif_EF-hand-BS,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,smart_Myosin_head_motor_dom,smart_IQ_motif_EF-hand-BS,pfscan_IQ_motif_EF-hand-BS,pfscan_Prot_kinase_cat_dom,prints_Myosin_head_motor_dom - no_errors MYO3B HGNC ENSG00000071909 77 0 0.00 63 31 32.98 - - - NUP98 0 genome.wustl.edu 37 11 3723746 3723746 + Missense_Mutation SNP C C A TCGA-AR-A2LL-01A-11D-A17W-09 TCGA-AR-A2LL-10A-01D-A17W-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9b2fb8e3-62a1-45b0-9d8d-c2b2e9d392ee 2db1c6af-2da9-4408-b5cf-b1f0e65ec6e0 11 3723746 3723746 C A SNP NUP98 ENST00000324932 human ensembl 69_37n -1 known missense c.3459 p.Q1153H 0.306 NULL pfam_Nup96,pfam_Peptidase_S59,superfamily_Peptidase_S59 - no_errors NUP98 HGNC ENSG00000110713 48 0 0.00 36 20 35.71 - - - OR4C5 0 genome.wustl.edu 37 11 48387505 48387505 + Silent SNP G G A TCGA-AR-A2LL-01A-11D-A17W-09 TCGA-AR-A2LL-10A-01D-A17W-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9b2fb8e3-62a1-45b0-9d8d-c2b2e9d392ee 2db1c6af-2da9-4408-b5cf-b1f0e65ec6e0 11 48387505 48387505 G A SNP OR4C5 ENST00000319813 human ensembl 69_37n -1 known silent c.513 p.V171 0.000 pfam_7TM_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_supfam pfam_7TM_GPCR_Rhodpsn,prints_Olfact_rcpt,prints_7TM_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_supfam - no_errors OR4C5 HGNC ENSG00000176540 20 0 0.00 11 5 31.25 - - - OR4F17 0 genome.wustl.edu 37 19 111016 111016 + Missense_Mutation SNP T T G TCGA-AR-A2LL-01A-11D-A17W-09 TCGA-AR-A2LL-10A-01D-A17W-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9b2fb8e3-62a1-45b0-9d8d-c2b2e9d392ee 2db1c6af-2da9-4408-b5cf-b1f0e65ec6e0 19 111016 111016 T G SNP OR4F17 ENST00000318050 human ensembl 69_37n +1 known missense c.338 p.F113C 0.999 pfam_7TM_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_supfam,prints_7TM_GPCR_Rhodpsn pfam_7TM_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_supfam,prints_Olfact_rcpt,prints_7TM_GPCR_Rhodpsn - no_errors OR4F17 HGNC ENSG00000176695 20 0 0.00 7 4 36.36 - - - OR8K3 0 genome.wustl.edu 37 11 56086657 56086657 + Missense_Mutation SNP G G A TCGA-AR-A2LL-01A-11D-A17W-09 TCGA-AR-A2LL-10A-01D-A17W-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9b2fb8e3-62a1-45b0-9d8d-c2b2e9d392ee 2db1c6af-2da9-4408-b5cf-b1f0e65ec6e0 11 56086657 56086657 G A SNP OR8K3 ENST00000312711 human ensembl 69_37n +1 known missense c.875 p.R292Q 0.997 prints_Olfact_rcpt,prints_7TM_GPCR_Rhodpsn pfam_7TM_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_supfam,prints_Olfact_rcpt,prints_7TM_GPCR_Rhodpsn - no_errors OR8K3 HGNC ENSG00000181689 66 0 0.00 49 6 10.91 - - - PTEN 0 genome.wustl.edu 37 10 89692886 89692886 + Missense_Mutation SNP T T A TCGA-AR-A2LL-01A-11D-A17W-09 TCGA-AR-A2LL-10A-01D-A17W-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9b2fb8e3-62a1-45b0-9d8d-c2b2e9d392ee 2db1c6af-2da9-4408-b5cf-b1f0e65ec6e0 10 89692886 89692886 T A SNP PTEN ENST00000371953 human ensembl 69_37n +1 known missense c.370 p.C124S 1.000 pfam_Dual-sp_phosphatase_cat-dom,pfam_Tyr_Pase_rcpt/non-rcpt,smart_Tyr_Pase_cat,pirsf_Bifunc_PIno_P3_Pase/Pase_PTEN,pfscan_Tyr/Dual-specificity_Pase,pfscan_Phosphatase_tensin-typ pfam_Tensin_phosphatase_C2-dom,pfam_Dual-sp_phosphatase_cat-dom,pfam_Tyr_Pase_rcpt/non-rcpt,superfamily_C2_Ca/lipid-bd_dom_CaLB,smart_Tyr_Pase_cat,pirsf_Bifunc_PIno_P3_Pase/Pase_PTEN,pfscan_Tyr/Dual-specificity_Pase,pfscan_Phosphatase_tensin-typ,pfscan_Tensin_phosphatase_C2-dom - no_errors PTEN HGNC ENSG00000171862 94 0 0.00 28 27 49.09 - - - RAPGEF4 0 genome.wustl.edu 37 2 173891911 173891911 + Missense_Mutation SNP G G A TCGA-AR-A2LL-01A-11D-A17W-09 TCGA-AR-A2LL-10A-01D-A17W-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9b2fb8e3-62a1-45b0-9d8d-c2b2e9d392ee 2db1c6af-2da9-4408-b5cf-b1f0e65ec6e0 2 173891911 173891911 G A SNP RAPGEF4 ENST00000397081 human ensembl 69_37n +1 known missense c.2482 p.V828I 1.000 pfam_RasGRF_CDC25,superfamily_Ras_GEF_dom,smart_RasGRF_CDC25,pfscan_RasGRF_CDC25 pfam_RasGRF_CDC25,pfam_cNMP-bd_dom,pfam_DEP_dom,pfam_Ras-like_Gua-exchang_fac_N,pfam_Ras-assoc,superfamily_Ras_GEF_dom,superfamily_cNMP-bd-like,smart_cNMP-bd_dom,smart_DEP_dom,smart_Ras-like_Gua-exchang_fac_N,smart_RasGRF_CDC25,pfscan_cNMP-bd_dom,pfscan_DEP_dom,pfscan_RasGRF_CDC25,pfscan_Ras-like_Gua-exchang_fac_N,prints_cAMP/cGMP_kin - no_errors RAPGEF4 HGNC ENSG00000091428 36 0 0.00 33 10 23.26 - - - RAPGEF6 0 genome.wustl.edu 37 5 130825308 130825308 + Missense_Mutation SNP A A C TCGA-AR-A2LL-01A-11D-A17W-09 TCGA-AR-A2LL-10A-01D-A17W-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9b2fb8e3-62a1-45b0-9d8d-c2b2e9d392ee 2db1c6af-2da9-4408-b5cf-b1f0e65ec6e0 5 130825308 130825308 A C SNP RAPGEF6 ENST00000509018 human ensembl 69_37n -1 known missense c.1771 p.F591V 0.968 pfam_PDZ,superfamily_Ras_GEF_dom,superfamily_PDZ,smart_PDZ,pfscan_PDZ pfam_RasGRF_CDC25,pfam_PDZ,pfam_Ras-assoc,pfam_cNMP-bd_dom,pfam_Ras-like_Gua-exchang_fac_N,superfamily_Ras_GEF_dom,superfamily_PDZ,superfamily_cNMP-bd-like,smart_cNMP-bd_dom,smart_Ras-like_Gua-exchang_fac_N,smart_PDZ,smart_Ras-assoc,smart_RasGRF_CDC25,pfscan_cNMP-bd_dom,pfscan_PDZ,pfscan_Ras-assoc,pfscan_RasGRF_CDC25,pfscan_Ras-like_Gua-exchang_fac_N - no_errors RAPGEF6 HGNC ENSG00000158987 68 0 0.00 55 35 38.89 - - - SIRPB2 0 genome.wustl.edu 37 20 1460499 1460499 + Missense_Mutation SNP G G C TCGA-AR-A2LL-01A-11D-A17W-09 TCGA-AR-A2LL-10A-01D-A17W-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9b2fb8e3-62a1-45b0-9d8d-c2b2e9d392ee 2db1c6af-2da9-4408-b5cf-b1f0e65ec6e0 20 1460499 1460499 G C SNP SIRPB2 ENST00000359801 human ensembl 69_37n -1 known missense c.297 p.I99M 0.147 pfam_Ig_V-set,smart_Ig_sub,smart_Ig_sub2,pfscan_Ig-like pfam_Ig_V-set,pfam_Ig_I-set,pfam_Immunoglobulin,smart_Ig_sub,smart_Ig_sub2,pfscan_Ig-like - no_errors SIRPB2 HGNC ENSG00000196209 46 0 0.00 75 19 20.21 - - - SOGA2 0 genome.wustl.edu 37 18 8784388 8784388 + Silent SNP G G A TCGA-AR-A2LL-01A-11D-A17W-09 TCGA-AR-A2LL-10A-01D-A17W-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9b2fb8e3-62a1-45b0-9d8d-c2b2e9d392ee 2db1c6af-2da9-4408-b5cf-b1f0e65ec6e0 18 8784388 8784388 G A SNP SOGA2 ENST00000359865 human ensembl 69_37n +1 known silent c.1278 p.S426 0.774 NULL pfam_DUF3166 - no_errors SOGA2 HGNC ENSG00000168502 27 0 0.00 25 5 16.67 - - - TUBA3C 0 genome.wustl.edu 37 13 19748238 19748238 + Missense_Mutation SNP C C T TCGA-AR-A2LL-01A-11D-A17W-09 TCGA-AR-A2LL-10A-01D-A17W-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9b2fb8e3-62a1-45b0-9d8d-c2b2e9d392ee 2db1c6af-2da9-4408-b5cf-b1f0e65ec6e0 13 19748238 19748238 C T SNP TUBA3C ENST00000400113 human ensembl 69_37n -1 known missense c.1118 p.R373Q 1.000 pfam_Tubulin/FtsZ_2-layer-sand-dom,superfamily_Tub_FtsZ_C,smart_Tubulin/FtsZ_2-layer-sand-dom,prints_Alpha_tubulin,prints_Delta_tubulin pfam_Tubulin_FtsZ_GTPase,pfam_Tubulin/FtsZ_2-layer-sand-dom,superfamily_Tubulin_FtsZ_GTPase,superfamily_Tub_FtsZ_C,smart_Tubulin_FtsZ_GTPase,smart_Tubulin/FtsZ_2-layer-sand-dom,prints_Alpha_tubulin,prints_Tubulin,prints_Epsilon_tubulin,prints_Delta_tubulin,prints_Beta_tubulin - no_errors TUBA3C HGNC ENSG00000198033 64 0 0.00 36 23 38.98 - - - WDR25 0 genome.wustl.edu 37 14 100847946 100847946 + Missense_Mutation SNP T T C TCGA-AR-A2LL-01A-11D-A17W-09 TCGA-AR-A2LL-10A-01D-A17W-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9b2fb8e3-62a1-45b0-9d8d-c2b2e9d392ee 2db1c6af-2da9-4408-b5cf-b1f0e65ec6e0 14 100847946 100847946 T C SNP WDR25 ENST00000335290 human ensembl 69_37n +1 known missense c.685 p.Y229H 0.001 superfamily_WD40_repeat_dom pfam_WD40_repeat,superfamily_WD40_repeat_dom,smart_WD40_repeat,pfscan_WD40_repeat,pfscan_WD40_repeat_dom - no_errors WDR25 HGNC ENSG00000176473 28 0 0.00 30 9 23.08 - - - WNT16 0 genome.wustl.edu 37 7 120969710 120969711 + Frame_Shift_Ins INS - - TT TCGA-AR-A2LL-01A-11D-A17W-09 TCGA-AR-A2LL-10A-01D-A17W-09 - - Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9b2fb8e3-62a1-45b0-9d8d-c2b2e9d392ee 2db1c6af-2da9-4408-b5cf-b1f0e65ec6e0 7 120969710 120969711 - TT INS WNT16 ENST00000222462 human ensembl 69_37n +1 known frame_shift_ins c.185_186 p.R62fs 0.992:1.000 pfam_Wnt,smart_Wnt pfam_Wnt,smart_Wnt,prints_Wnt16,prints_Wnt - no_errors WNT16 HGNC ENSG00000002745 15 0 0.00 27 7 20.59 - - -