Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values
RTF1	23168	broad.mit.edu	37	15	41763442	41763442	+	Silent	SNP	G	G	A			TCGA-06-0167-01A-01D-1491-08	TCGA-06-0167-10A-01D-1491-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d530c696-235d-4a41-944d-e7f7ae21aa17	74292da7-2a53-455d-8d33-438db411fa67	g.chr15:41763442G>A	uc001zny.3	+	7	1110	c.1098G>A	c.(1096-1098)cgG>cgA	p.R366R		NM_015138	NP_055953	Q92541	RTF1_HUMAN	Homo sapiens Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) (RTF1), mRNA.	366	Plus3.				histone modification|regulation of transcription, DNA-dependent|transcription initiation, DNA-dependent	nucleoplasm	protein binding|single-stranded DNA binding	p.R241R(1)		central_nervous_system(1)|endometrium(2)|kidney(3)|large_intestine(2)|lung(6)|ovary(2)|prostate(1)|skin(1)	18		all_cancers(109;1.79e-19)|all_epithelial(112;8.18e-17)|Lung NSC(122;3.16e-11)|all_lung(180;8.14e-10)|Melanoma(134;0.0179)|Colorectal(260;0.0946)|Ovarian(310;0.143)		OV - Ovarian serous cystadenocarcinoma(18;1.15e-16)|GBM - Glioblastoma multiforme(113;1.81e-06)|BRCA - Breast invasive adenocarcinoma(123;0.119)		GATTATCACGGCATAAGCTAG	0.458												
MRPL10	124995	broad.mit.edu	37	17	45905957	45905957	+	Silent	SNP	C	C	T			TCGA-06-0167-01A-01D-1491-08	TCGA-06-0167-10A-01D-1491-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d530c696-235d-4a41-944d-e7f7ae21aa17	74292da7-2a53-455d-8d33-438db411fa67	g.chr17:45905957C>T	uc002ily.3	-	2	260	c.162G>A	c.(160-162)cgG>cgA	p.R54R	MRPL10_uc002ilz.3_Silent_p.R44R|MRPL10_uc010wky.2_Silent_p.R5R	NM_148887	NP_683685	Q7Z7H8	RM10_HUMAN	Homo sapiens mitochondrial ribosomal protein L10 (MRPL10), nuclear gene encoding mitochondrial protein, transcript variant 2, mRNA.	44					ribosome biogenesis|translation	mitochondrial large ribosomal subunit	structural constituent of ribosome			endometrium(3)|large_intestine(1)|lung(3)|ovary(1)	8						TCAGCTTCTGCCGCTGAAAGT	0.597												
ITGB2	3689	broad.mit.edu	37	21	46326937	46326937	+	Missense_Mutation	SNP	G	G	A			TCGA-06-0167-01A-01D-1491-08	TCGA-06-0167-10A-01D-1491-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d530c696-235d-4a41-944d-e7f7ae21aa17	74292da7-2a53-455d-8d33-438db411fa67	g.chr21:46326937G>A	uc002zgd.2	-	2	265	c.221C>T	c.(220-222)gCg>gTg	p.A74V	ITGB2_uc002zgf.3_Missense_Mutation_p.A74V|ITGB2_uc011afl.1_5'UTR|ITGB2_uc010gpw.2_Missense_Mutation_p.A74V|ITGB2_uc002zgg.2_Missense_Mutation_p.A74V	NM_001127491	NP_001120963	P05107	ITB2_HUMAN	Homo sapiens integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) (ITGB2), transcript variant 2, mRNA.	74					apoptosis|blood coagulation|cell-cell signaling|cell-matrix adhesion|inflammatory response|integrin-mediated signaling pathway|leukocyte cell-cell adhesion|multicellular organismal development|neutrophil chemotaxis|regulation of cell shape|regulation of immune response|regulation of peptidyl-tyrosine phosphorylation	integrin complex	glycoprotein binding|protein kinase binding|receptor activity			breast(2)|central_nervous_system(3)|endometrium(2)|kidney(1)|large_intestine(6)|lung(14)|ovary(4)|skin(3)	35				Colorectal(79;0.0669)	Simvastatin(DB00641)	GTCGTCAGCCGCACAGCCCCT	0.617												
NPNT	255743	broad.mit.edu	37	4	106888371	106888371	+	Missense_Mutation	SNP	G	G	A	rs146652028		TCGA-06-0167-01A-01D-1491-08	TCGA-06-0167-10A-01D-1491-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d530c696-235d-4a41-944d-e7f7ae21aa17	74292da7-2a53-455d-8d33-438db411fa67	g.chr4:106888371G>A	uc011cfd.2	+	11	1675	c.1462G>A	c.(1462-1464)Gcc>Acc	p.A488T	NPNT_uc011cfc.2_Missense_Mutation_p.A475T|NPNT_uc011cfe.2_Missense_Mutation_p.A459T|NPNT_uc003hya.3_Missense_Mutation_p.A458T|NPNT_uc011cff.2_Missense_Mutation_p.A429T	NM_001184691	NP_001171620	Q6UXI9	NPNT_HUMAN	Homo sapiens nephronectin (NPNT), transcript variant 3, mRNA.	458	MAM.				cell differentiation	membrane	calcium ion binding	p.A458T(1)		kidney(5)|large_intestine(2)|lung(10)|prostate(2)|skin(1)|urinary_tract(1)	21		Hepatocellular(203;0.217)		OV - Ovarian serous cystadenocarcinoma(123;5.41e-07)		AGTGTCGGCAGCCAAAGCCCC	0.552												
SEC24B	10427	broad.mit.edu	37	4	110437770	110437770	+	Silent	SNP	C	C	T			TCGA-06-0167-01A-01D-1491-08	TCGA-06-0167-10A-01D-1491-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d530c696-235d-4a41-944d-e7f7ae21aa17	74292da7-2a53-455d-8d33-438db411fa67	g.chr4:110437770C>T	uc003hzk.3	+	10	2155	c.2100C>T	c.(2098-2100)tgC>tgT	p.C700C	SEC24B_uc003hzl.3_Silent_p.C665C|SEC24B_uc011cfp.2_Silent_p.C730C|SEC24B_uc011cfq.2_Silent_p.C699C|SEC24B_uc011cfr.2_Silent_p.C664C	NM_006323	NP_006314	O95487	SC24B_HUMAN	Homo sapiens SEC24 family, member B (S. cerevisiae) (SEC24B), transcript variant 1, mRNA.	700					COPII vesicle coating|intracellular protein transport|post-translational protein modification|protein N-linked glycosylation via asparagine	COPII vesicle coat|cytosol|endoplasmic reticulum membrane|Golgi membrane|perinuclear region of cytoplasm	protein binding|transporter activity|zinc ion binding			breast(1)|endometrium(7)|kidney(1)|large_intestine(10)|lung(12)|ovary(2)|prostate(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	36		Hepatocellular(203;0.217)		OV - Ovarian serous cystadenocarcinoma(123;3.03e-05)		CAATTTTGTGCCAGTCACTCC	0.318												
C6orf203	51250	broad.mit.edu	37	6	107372330	107372330	+	Missense_Mutation	SNP	C	C	T			TCGA-06-0167-01A-01D-1491-08	TCGA-06-0167-10A-01D-1491-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d530c696-235d-4a41-944d-e7f7ae21aa17	74292da7-2a53-455d-8d33-438db411fa67	g.chr6:107372330C>T	uc011eaj.2	+	4	1303	c.628C>T	c.(628-630)Cgg>Tgg	p.R210W	C6orf203_uc003prq.3_Missense_Mutation_p.R205W|C6orf203_uc010kde.3_Missense_Mutation_p.R205W	NM_001142470	NP_057571	Q9P0P8	CF203_HUMAN	Homo sapiens chromosome 6 open reading frame 203 (C6orf203), transcript variant 3, mRNA.	205										large_intestine(4)|lung(2)|prostate(1)|urinary_tract(1)	8	Breast(9;0.00124)|all_epithelial(6;0.0729)	all_cancers(87;0.00461)|Acute lymphoblastic leukemia(125;3.07e-08)|all_hematologic(75;3.33e-06)|Colorectal(196;0.171)|all_epithelial(87;0.23)	BRCA - Breast invasive adenocarcinoma(8;0.000395)|all cancers(7;0.00065)|Epithelial(6;0.000834)|OV - Ovarian serous cystadenocarcinoma(5;0.244)	BRCA - Breast invasive adenocarcinoma(108;0.117)		GACAGTTATGCGGATTCTCTT	0.383												
MSL3	10943	broad.mit.edu	37	X	11790350	11790350	+	Missense_Mutation	SNP	G	G	A	rs140880282		TCGA-06-0167-01A-01D-1491-08	TCGA-06-0167-10A-01D-1491-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d530c696-235d-4a41-944d-e7f7ae21aa17	74292da7-2a53-455d-8d33-438db411fa67	g.chrX:11790350G>A	uc004cuw.3	+	10	1462	c.1357G>A	c.(1357-1359)Gca>Aca	p.A453T	MSL3_uc011mig.2_Missense_Mutation_p.A304T|MSL3_uc011mih.2_Missense_Mutation_p.A441T|MSL3_uc004cuy.3_Missense_Mutation_p.A287T	NM_078629	NP_006791	Q8N5Y2	MS3L1_HUMAN	Homo sapiens male-specific lethal 3 homolog (Drosophila) (MSL3), transcript variant 1, mRNA.	453					histone H4-K16 acetylation|multicellular organismal development|transcription from RNA polymerase II promoter	MSL complex	DNA binding|methylated histone residue binding|sequence-specific DNA binding transcription factor activity			breast(1)|central_nervous_system(3)|cervix(1)|kidney(3)|large_intestine(3)|lung(6)|ovary(1)|urinary_tract(1)	19						CATTTATGGGGCACAACATTT	0.463