Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_status	validation_method	validation_tumor_sample	validation_alt_allele	pox	qox	isArtifactMode	oxoGCut
GPR153	387509	broad.mit.edu	37	1	6313858	6313858	+	Missense_Mutation	SNP	C	C	T			TCGA-CR-5249-01A-01D-1512-08	TCGA-CR-5249-10A-01D-1512-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	42bf9ca3-47d8-45ff-bccf-bda80af58d22	25a6fe65-a78b-4adc-8ce7-1bc2bc4bbf48	g.chr1:6313858C>T	uc001amp.1	-	3	966	c.706G>A	c.(706-708)GCC>ACC	p.A236T		NM_207370	NP_997253	Q6NV75	GP153_HUMAN	G protein-coupled receptor 153	236	Cytoplasmic (Potential).					integral to membrane|plasma membrane	G-protein coupled receptor activity				0	Ovarian(185;0.0634)	all_cancers(23;8.07e-33)|all_epithelial(116;4.45e-18)|all_lung(118;1.09e-06)|all_neural(13;3.68e-06)|Lung NSC(185;1.52e-05)|all_hematologic(16;2.39e-05)|Acute lymphoblastic leukemia(12;0.000372)|Glioma(11;0.00127)|Renal(390;0.00188)|Colorectal(325;0.00342)|Breast(487;0.00475)|Hepatocellular(190;0.0218)|Myeloproliferative disorder(586;0.0393)|Ovarian(437;0.15)		Epithelial(90;1.91e-37)|GBM - Glioblastoma multiforme(13;4.87e-29)|OV - Ovarian serous cystadenocarcinoma(86;3.03e-19)|Colorectal(212;1.33e-07)|COAD - Colon adenocarcinoma(227;1.36e-05)|Kidney(185;4.89e-05)|KIRC - Kidney renal clear cell carcinoma(229;0.000911)|BRCA - Breast invasive adenocarcinoma(365;0.00109)|STAD - Stomach adenocarcinoma(132;0.00313)|READ - Rectum adenocarcinoma(331;0.0642)|Lung(427;0.246)		GAGGTTTTGGCGGGCTCCGAG	0.677		NA											3	61					0	0	0	0
LHX9	56956	broad.mit.edu	37	1	197896796	197896796	+	Missense_Mutation	SNP	T	T	C			TCGA-CR-5249-01A-01D-1512-08	TCGA-CR-5249-10A-01D-1512-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	42bf9ca3-47d8-45ff-bccf-bda80af58d22	25a6fe65-a78b-4adc-8ce7-1bc2bc4bbf48	g.chr1:197896796T>C	uc001guk.1	+	4	1246	c.809T>C	c.(808-810)ATG>ACG	p.M270T	LHX9_uc001gui.1_Missense_Mutation_p.M261T|LHX9_uc001guj.1_Missense_Mutation_p.M276T	NM_020204	NP_064589	Q9NQ69	LHX9_HUMAN	LIM homeobox 9 isoform 1	270	Homeobox.				motor axon guidance|negative regulation of transcription, DNA-dependent	nucleus	sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity|transcription corepressor activity|zinc ion binding			ovary(1)	1						ACCAAGCGCATGCGAACCTCT	0.522		NA											9	348					0	0	0	0
CNTN2	6900	broad.mit.edu	37	1	205038678	205038678	+	Missense_Mutation	SNP	G	G	A			TCGA-CR-5249-01A-01D-1512-08	TCGA-CR-5249-10A-01D-1512-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	42bf9ca3-47d8-45ff-bccf-bda80af58d22	25a6fe65-a78b-4adc-8ce7-1bc2bc4bbf48	g.chr1:205038678G>A	uc001hbr.2	+	17	2454	c.2185G>A	c.(2185-2187)GTC>ATC	p.V729I	CNTN2_uc001hbq.1_Missense_Mutation_p.V620I|CNTN2_uc001hbs.2_Missense_Mutation_p.V517I	NM_005076	NP_005067	Q02246	CNTN2_HUMAN	contactin 2 precursor	729	Fibronectin type-III 2.				axon guidance|clustering of voltage-gated potassium channels	anchored to membrane|juxtaparanode region of axon|myelin sheath|node of Ranvier|synapse part	identical protein binding			ovary(1)	1	all_cancers(21;0.144)|Breast(84;0.0437)		KIRC - Kidney renal clear cell carcinoma(13;0.0584)|Kidney(21;0.0934)|BRCA - Breast invasive adenocarcinoma(75;0.158)			AGAGCTCATCGTCAACTGGAC	0.612		NA											3	34					0	0	0	0
BMS1	9790	broad.mit.edu	37	10	43318580	43318580	+	Silent	SNP	T	T	A			TCGA-CR-5249-01A-01D-1512-08	TCGA-CR-5249-10A-01D-1512-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	42bf9ca3-47d8-45ff-bccf-bda80af58d22	25a6fe65-a78b-4adc-8ce7-1bc2bc4bbf48	g.chr10:43318580T>A	uc001jaj.2	+	20	3505	c.3147T>A	c.(3145-3147)TCT>TCA	p.S1049S		NM_014753	NP_055568	Q14692	BMS1_HUMAN	BMS1-like, ribosome assembly protein	1049					ribosome assembly	nucleolus	ATP binding|GTP binding|GTPase activity			ovary(2)|upper_aerodigestive_tract(1)	3						TGTTTAATTCTGCCTTGGAAG	0.403		NA											4	165					0	0	0	0
SORCS1	114815	broad.mit.edu	37	10	108448071	108448071	+	Missense_Mutation	SNP	A	A	G			TCGA-CR-5249-01A-01D-1512-08	TCGA-CR-5249-10A-01D-1512-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	42bf9ca3-47d8-45ff-bccf-bda80af58d22	25a6fe65-a78b-4adc-8ce7-1bc2bc4bbf48	g.chr10:108448071A>G	uc001kym.2	-	10	1447	c.1439T>C	c.(1438-1440)TTG>TCG	p.L480S	SORCS1_uc001kyl.2_Missense_Mutation_p.L480S|SORCS1_uc009xxs.2_Missense_Mutation_p.L480S|SORCS1_uc001kyn.1_Missense_Mutation_p.L480S|SORCS1_uc001kyo.2_Missense_Mutation_p.L480S	NM_052918	NP_443150	Q8WY21	SORC1_HUMAN	SORCS receptor 1 isoform a	480	Lumenal (Potential).					integral to membrane	neuropeptide receptor activity|protein binding			breast(1)|central_nervous_system(1)	2		Breast(234;0.0256)|Colorectal(252;0.09)|Lung NSC(174;0.168)		Epithelial(162;1.66e-05)|all cancers(201;0.000689)		CTTGTTAGCCAAGAACATTCC	0.403		NA											3	96					0	0	0	0
PTPRE	5791	broad.mit.edu	37	10	129877950	129877950	+	Silent	SNP	G	G	A			TCGA-CR-5249-01A-01D-1512-08	TCGA-CR-5249-10A-01D-1512-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	42bf9ca3-47d8-45ff-bccf-bda80af58d22	25a6fe65-a78b-4adc-8ce7-1bc2bc4bbf48	g.chr10:129877950G>A	uc001lkb.2	+	20	2298	c.2019G>A	c.(2017-2019)GTG>GTA	p.V673V	PTPRE_uc009yat.2_Silent_p.V684V|PTPRE_uc009yau.2_Silent_p.V673V|PTPRE_uc001lkd.2_Silent_p.V615V|PTPRE_uc010quq.1_Intron	NM_006504	NP_006495	P23469	PTPRE_HUMAN	protein tyrosine phosphatase, receptor type, E	673	Tyrosine-protein phosphatase 2.|Cytoplasmic (Potential).				negative regulation of insulin receptor signaling pathway|protein phosphorylation	cytoplasm|integral to membrane|intermediate filament cytoskeleton|nucleus|plasma membrane	transmembrane receptor protein tyrosine phosphatase activity			ovary(1)	1		all_epithelial(44;1.66e-05)|all_lung(145;0.00456)|Lung NSC(174;0.0066)|all_neural(114;0.0936)|Colorectal(57;0.141)|Breast(234;0.166)|Melanoma(40;0.203)				CACATATGGTGCAAACCCTGG	0.383		NA											27	100					0	0	0	0
KCNA4	3739	broad.mit.edu	37	11	30032800	30032800	+	Missense_Mutation	SNP	G	G	A			TCGA-CR-5249-01A-01D-1512-08	TCGA-CR-5249-10A-01D-1512-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	42bf9ca3-47d8-45ff-bccf-bda80af58d22	25a6fe65-a78b-4adc-8ce7-1bc2bc4bbf48	g.chr11:30032800G>A	uc001msk.2	-	2	2578	c.1426C>T	c.(1426-1428)CGG>TGG	p.R476W		NM_002233	NP_002224	P22459	KCNA4_HUMAN	potassium voltage-gated channel, shaker-related	476						voltage-gated potassium channel complex	potassium ion binding|protein binding|voltage-gated potassium channel activity			ovary(2)|central_nervous_system(1)|pancreas(1)	4						CCCAGTTCCCGCATGCTGGCT	0.522		NA											8	79					0	0	0	0
OR4A5	81318	broad.mit.edu	37	11	51411725	51411725	+	Missense_Mutation	SNP	G	G	A			TCGA-CR-5249-01A-01D-1512-08	TCGA-CR-5249-10A-01D-1512-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	42bf9ca3-47d8-45ff-bccf-bda80af58d22	25a6fe65-a78b-4adc-8ce7-1bc2bc4bbf48	g.chr11:51411725G>A	uc001nhi.1	-	1	671	c.671C>T	c.(670-672)ACT>ATT	p.T224I		NM_001005272	NP_001005272	Q8NH83	OR4A5_HUMAN	olfactory receptor, family 4, subfamily A,	224	Cytoplasmic (Potential).				sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			ovary(1)|central_nervous_system(1)|skin(1)	3		all_lung(304;0.236)				CTGACTGTAAGTTTTAAGGGA	0.413		NA											13	102					0	0	0	0
SLC22A25	387601	broad.mit.edu	37	11	62997044	62997044	+	Missense_Mutation	SNP	G	G	C			TCGA-CR-5249-01A-01D-1512-08	TCGA-CR-5249-10A-01D-1512-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	42bf9ca3-47d8-45ff-bccf-bda80af58d22	25a6fe65-a78b-4adc-8ce7-1bc2bc4bbf48	g.chr11:62997044G>C	uc001nwr.1	-	1	81	c.81C>G	c.(79-81)TTC>TTG	p.F27L	SLC22A10_uc010rmo.1_Intron|SLC22A25_uc009yoq.1_RNA|SLC22A25_uc001nws.1_RNA|SLC22A25_uc001nwt.1_Missense_Mutation_p.F27L	NM_199352	NP_955384	Q6T423	S22AP_HUMAN	putative UST1-like organic anion transporter	27	Helical; Name=1; (Potential).				transmembrane transport	integral to membrane				ovary(3)|skin(1)	4						CTATGACGTTGAACATTATAA	0.463		NA											5	123					0	0	0	0
SC5DL	6309	broad.mit.edu	37	11	121178029	121178029	+	Silent	SNP	T	T	C			TCGA-CR-5249-01A-01D-1512-08	TCGA-CR-5249-10A-01D-1512-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	42bf9ca3-47d8-45ff-bccf-bda80af58d22	25a6fe65-a78b-4adc-8ce7-1bc2bc4bbf48	g.chr11:121178029T>C	uc001pxu.2	+	5	856	c.708T>C	c.(706-708)TTT>TTC	p.F236F	SC5DL_uc001pxt.2_3'UTR|SC5DL_uc001pxv.2_Silent_p.F236F	NM_006918	NP_008849	O75845	SC5D_HUMAN	sterol-C5-desaturase	236				PQILQPFINGSAHHTDHHMFFDYNYGQYFTLWDRIGGSFKN PSSFEGKGPLSYVKEMTEGKRSSHSGNGCKNEKLFNGEFTK TE -> RMKNYSMESLQRLNRLLPSYS (in Ref. 1; BAA18970).	fatty acid biosynthetic process	endoplasmic reticulum membrane|integral to membrane	C-5 sterol desaturase activity|iron ion binding|lathosterol oxidase activity			ovary(1)	1		Breast(109;0.00328)|Medulloblastoma(222;0.0425)|all_neural(223;0.112)	OV - Ovarian serous cystadenocarcinoma(1;0.0334)	BRCA - Breast invasive adenocarcinoma(274;5.1e-06)|OV - Ovarian serous cystadenocarcinoma(223;0.144)		ATATGTTCTTTGACTATAATT	0.413		NA											10	191					0	0	0	0
KRT7	3855	broad.mit.edu	37	12	52639289	52639289	+	Missense_Mutation	SNP	G	G	A			TCGA-CR-5249-01A-01D-1512-08	TCGA-CR-5249-10A-01D-1512-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	42bf9ca3-47d8-45ff-bccf-bda80af58d22	25a6fe65-a78b-4adc-8ce7-1bc2bc4bbf48	g.chr12:52639289G>A	uc001saa.1	+	7	1205	c.1078G>A	c.(1078-1080)GCC>ACC	p.A360T	KRT7_uc009zmf.1_Intron	NM_005556	NP_005547	P08729	K2C7_HUMAN	keratin 7	360	Rod.|Coil 2.				cytoskeleton organization|DNA replication|interphase|interspecies interaction between organisms|regulation of translation	Golgi apparatus|keratin filament|nucleus	protein binding|structural molecule activity				0				BRCA - Breast invasive adenocarcinoma(357;0.105)		GCTGGAAGCCGCCCTGCAGCG	0.652		NA											5	54					0	0	0	0
HECTD1	25831	broad.mit.edu	37	14	31602803	31602803	+	Silent	SNP	C	C	T			TCGA-CR-5249-01A-01D-1512-08	TCGA-CR-5249-10A-01D-1512-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	42bf9ca3-47d8-45ff-bccf-bda80af58d22	25a6fe65-a78b-4adc-8ce7-1bc2bc4bbf48	g.chr14:31602803C>T	uc001wrc.1	-	23	4146	c.3657G>A	c.(3655-3657)GGG>GGA	p.G1219G	HECTD1_uc001wrd.1_Silent_p.G734G	NM_015382	NP_056197	Q9ULT8	HECD1_HUMAN	HECT domain containing 1	1219					protein ubiquitination involved in ubiquitin-dependent protein catabolic process	intracellular	metal ion binding|protein binding|ubiquitin-protein ligase activity			ovary(3)|large_intestine(1)|lung(1)	5	Hepatocellular(127;0.0877)|Breast(36;0.176)		LUAD - Lung adenocarcinoma(48;0.00292)|Lung(238;0.0164)|BRCA - Breast invasive adenocarcinoma(188;0.111)|STAD - Stomach adenocarcinoma(7;0.173)	GBM - Glioblastoma multiforme(265;0.00617)		TGGCATTTTTCCCCATCTGTT	0.403		NA											27	101					0	0	0	0
SAMD4A	23034	broad.mit.edu	37	14	55168922	55168922	+	Silent	SNP	T	T	C			TCGA-CR-5249-01A-01D-1512-08	TCGA-CR-5249-10A-01D-1512-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	42bf9ca3-47d8-45ff-bccf-bda80af58d22	25a6fe65-a78b-4adc-8ce7-1bc2bc4bbf48	g.chr14:55168922T>C	uc001xbb.2	+	2	337	c.336T>C	c.(334-336)ATT>ATC	p.I112I	SAMD4A_uc001xba.2_Silent_p.I112I|SAMD4A_uc001xbc.2_Silent_p.I112I|SAMD4A_uc001xbf.1_RNA|SAMD4A_uc001xbe.2_Silent_p.I12I	NM_015589	NP_056404	Q9UPU9	SMAG1_HUMAN	sterile alpha motif domain containing 4 isoform	113					positive regulation of translation	cell junction|cytoplasm|dendrite|synapse|synaptosome	translation repressor activity				0						CTCACTCTATTGAACACAACC	0.483		NA											26	88					0	0	0	0
TMEM202	338949	broad.mit.edu	37	15	72691006	72691006	+	Missense_Mutation	SNP	G	G	A			TCGA-CR-5249-01A-01D-1512-08	TCGA-CR-5249-10A-01D-1512-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	42bf9ca3-47d8-45ff-bccf-bda80af58d22	25a6fe65-a78b-4adc-8ce7-1bc2bc4bbf48	g.chr15:72691006G>A	uc002auq.2	+	2	94	c.94G>A	c.(94-96)GCC>ACC	p.A32T	TMEM202_uc002aur.2_Intron	NM_001080462	NP_001073931	A6NGA9	TM202_HUMAN	transmembrane protein 202	32						integral to membrane				central_nervous_system(1)|skin(1)	2						TACCGTCCCTGCCAAGAAACA	0.532		NA											17	65					0	0	0	0
CACNA1H	8912	broad.mit.edu	37	16	1250512	1250512	+	Missense_Mutation	SNP	C	C	T			TCGA-CR-5249-01A-01D-1512-08	TCGA-CR-5249-10A-01D-1512-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	42bf9ca3-47d8-45ff-bccf-bda80af58d22	25a6fe65-a78b-4adc-8ce7-1bc2bc4bbf48	g.chr16:1250512C>T	uc002cks.2	+	7	1308	c.1060C>T	c.(1060-1062)CCC>TCC	p.P354S	CACNA1H_uc002ckt.2_Missense_Mutation_p.P354S	NM_021098	NP_066921	O95180	CAC1H_HUMAN	calcium channel, voltage-dependent, T type,	354	Extracellular (Potential).|I.				aldosterone biosynthetic process|axon guidance|cellular response to hormone stimulus|cellular response to potassium ion|cortisol biosynthetic process|muscle contraction|myoblast fusion|positive regulation of acrosome reaction|regulation of heart contraction	voltage-gated calcium channel complex	low voltage-gated calcium channel activity			breast(2)	2		Hepatocellular(780;0.00369)			Flunarizine(DB04841)|Mibefradil(DB01388)	TGACTCCAACCCCCACAACGG	0.652		NA											3	67					0	0	0	0
ABCC11	85320	broad.mit.edu	37	16	48221269	48221269	+	Missense_Mutation	SNP	C	C	T			TCGA-CR-5249-01A-01D-1512-08	TCGA-CR-5249-10A-01D-1512-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	42bf9ca3-47d8-45ff-bccf-bda80af58d22	25a6fe65-a78b-4adc-8ce7-1bc2bc4bbf48	g.chr16:48221269C>T	uc002eff.1	-	20	3126	c.2776G>A	c.(2776-2778)GAC>AAC	p.D926N	ABCC11_uc002efg.1_Missense_Mutation_p.D926N|ABCC11_uc002efh.1_Missense_Mutation_p.D926N|ABCC11_uc010vgk.1_RNA|ABCC11_uc010cbg.1_RNA	NM_033151	NP_149163	Q96J66	ABCCB_HUMAN	ATP-binding cassette, sub-family C, member 11	926	ABC transmembrane type-1 2.					integral to membrane	ATP binding|ATPase activity, coupled to transmembrane movement of substances			ovary(3)|skin(2)|central_nervous_system(1)	6		all_cancers(37;0.127)|all_lung(18;0.132)|Breast(268;0.166)				TGTTCCAAGTCCCCTGCGAAG	0.527		NA							Cerumen_Type				21	37					0	0	0	0
VPS4A	27183	broad.mit.edu	37	16	69349972	69349972	+	Missense_Mutation	SNP	C	C	T			TCGA-CR-5249-01A-01D-1512-08	TCGA-CR-5249-10A-01D-1512-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	42bf9ca3-47d8-45ff-bccf-bda80af58d22	25a6fe65-a78b-4adc-8ce7-1bc2bc4bbf48	g.chr16:69349972C>T	uc002eww.2	+	2	211	c.83C>T	c.(82-84)GCG>GTG	p.A28V		NM_013245	NP_037377	Q9UN37	VPS4A_HUMAN	vacuolar protein sorting factor 4A	28	Interaction with CHMP1B.|MIT.				cell cycle|cellular membrane organization|cytokinesis|endosome transport|protein transport	cytosol|late endosome membrane|midbody|perinuclear region of cytoplasm	ATP binding|ATPase activity, coupled|protein C-terminus binding|protein domain specific binding				0		Ovarian(137;0.101)				TACGAGGAGGCGCTGCGGCTG	0.577		NA											4	115					0	0	0	0
WWP2	11060	broad.mit.edu	37	16	69922039	69922039	+	Silent	SNP	C	C	A			TCGA-CR-5249-01A-01D-1512-08	TCGA-CR-5249-10A-01D-1512-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	42bf9ca3-47d8-45ff-bccf-bda80af58d22	25a6fe65-a78b-4adc-8ce7-1bc2bc4bbf48	g.chr16:69922039C>A	uc002exu.1	+	9	890	c.801C>A	c.(799-801)CCC>CCA	p.P267P	WWP2_uc002ext.2_Silent_p.P267P|WWP2_uc002exv.1_Silent_p.P267P|WWP2_uc010vlm.1_Silent_p.P151P	NM_007014	NP_008945	O00308	WWP2_HUMAN	WW domain containing E3 ubiquitin protein ligase	267					entry of virus into host cell|negative regulation of protein transport|negative regulation of sequence-specific DNA binding transcription factor activity|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transporter activity|proteasomal ubiquitin-dependent protein catabolic process|protein K63-linked ubiquitination|protein ubiquitination involved in ubiquitin-dependent protein catabolic process	cytoplasm|nucleus|ubiquitin ligase complex	RNA polymerase II transcription factor binding|ubiquitin-protein ligase activity			lung(3)|ovary(1)|breast(1)|skin(1)	6						CCCCGAATCCCAACACGACTT	0.617		NA											20	78					4.35e-09	4.86e-09	1	0
CHST6	4166	broad.mit.edu	37	16	75512887	75512887	+	Silent	SNP	C	C	T			TCGA-CR-5249-01A-01D-1512-08	TCGA-CR-5249-10A-01D-1512-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	42bf9ca3-47d8-45ff-bccf-bda80af58d22	25a6fe65-a78b-4adc-8ce7-1bc2bc4bbf48	g.chr16:75512887C>T	uc002fef.2	-	3	1020	c.840G>A	c.(838-840)CCG>CCA	p.P280P	CHST6_uc002feg.1_RNA|CHST6_uc002feh.1_Silent_p.P280P	NM_021615	NP_067628	Q9GZX3	CHST6_HUMAN	carbohydrate (N-acetylglucosamine 6-O)	280	Lumenal (Potential).				keratan sulfate biosynthetic process|N-acetylglucosamine metabolic process	Golgi membrane|integral to membrane	N-acetylglucosamine 6-O-sulfotransferase activity				0						TTTCTGCCAGCGGCTCCCGCG	0.662		NA											15	49					0	0	0	0
SLC13A5	284111	broad.mit.edu	37	17	6606290	6606290	+	Missense_Mutation	SNP	C	C	T			TCGA-CR-5249-01A-01D-1512-08	TCGA-CR-5249-10A-01D-1512-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	42bf9ca3-47d8-45ff-bccf-bda80af58d22	25a6fe65-a78b-4adc-8ce7-1bc2bc4bbf48	g.chr17:6606290C>T	uc002gdj.2	-	5	803	c.715G>A	c.(715-717)GAG>AAG	p.E239K	SLC13A5_uc010vtf.1_Missense_Mutation_p.E239K|SLC13A5_uc010clq.2_Missense_Mutation_p.E196K|SLC13A5_uc002gdk.2_Missense_Mutation_p.E222K|SLC13A5_uc002gdl.1_Missense_Mutation_p.E221K	NM_177550	NP_808218	Q86YT5	S13A5_HUMAN	solute carrier family 13, member 5 isoform a	239						integral to membrane	citrate transmembrane transporter activity				0						AGGACTCACTCGTTCATCTGG	0.647		NA											22	95					0	0	0	0
DLX3	1747	broad.mit.edu	37	17	48070809	48070809	+	Silent	SNP	G	G	A			TCGA-CR-5249-01A-01D-1512-08	TCGA-CR-5249-10A-01D-1512-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	42bf9ca3-47d8-45ff-bccf-bda80af58d22	25a6fe65-a78b-4adc-8ce7-1bc2bc4bbf48	g.chr17:48070809G>A	uc002ipy.2	-	2	697	c.471C>T	c.(469-471)CCC>CCT	p.P157P		NM_005220	NP_005211	O60479	DLX3_HUMAN	distal-less homeobox 3	157	Homeobox.					nucleus	sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity				0						CGGCGCGCTCGGGCAGCGCCA	0.706		NA											7	22					0	0	0	0
GRIN2C	2905	broad.mit.edu	37	17	72840467	72840467	+	Missense_Mutation	SNP	C	C	T			TCGA-CR-5249-01A-01D-1512-08	TCGA-CR-5249-10A-01D-1512-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	42bf9ca3-47d8-45ff-bccf-bda80af58d22	25a6fe65-a78b-4adc-8ce7-1bc2bc4bbf48	g.chr17:72840467C>T	uc002jlt.1	-	12	2687	c.2531G>A	c.(2530-2532)CGC>CAC	p.R844H	GRIN2C_uc010wrh.1_RNA|GRIN2C_uc002jlu.1_Missense_Mutation_p.R844H	NM_000835	NP_000826	Q14957	NMDE3_HUMAN	N-methyl-D-aspartate receptor subunit 2C	844	Cytoplasmic (Potential).				glutamate signaling pathway	cell junction|outer membrane-bounded periplasmic space|postsynaptic membrane	extracellular-glutamate-gated ion channel activity|N-methyl-D-aspartate selective glutamate receptor activity			ovary(2)|breast(2)	4	all_lung(278;0.172)|Lung NSC(278;0.207)				Glycine(DB00145)|L-Glutamic Acid(DB00142)|Loperamide(DB00836)	CACCGAGTGGCGCAGCTTCCA	0.617		NA											4	110					0	0	0	0
SLC26A11	284129	broad.mit.edu	37	17	78195395	78195395	+	Missense_Mutation	SNP	G	G	T			TCGA-CR-5249-01A-01D-1512-08	TCGA-CR-5249-10A-01D-1512-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	42bf9ca3-47d8-45ff-bccf-bda80af58d22	25a6fe65-a78b-4adc-8ce7-1bc2bc4bbf48	g.chr17:78195395G>T	uc002jyb.1	+	3	305	c.36G>T	c.(34-36)AGG>AGT	p.R12S	SGSH_uc002jxz.3_5'Flank|SGSH_uc002jya.3_5'Flank|SGSH_uc002jxy.2_5'Flank|SGSH_uc010wue.1_5'Flank|SLC26A11_uc002jyc.1_Missense_Mutation_p.R12S|SLC26A11_uc002jyd.1_Missense_Mutation_p.R12S|SLC26A11_uc010dhv.1_Missense_Mutation_p.R12S	NM_173626	NP_775897	Q86WA9	S2611_HUMAN	solute carrier family 26, member 11	12	Extracellular (Potential).					endoplasmic reticulum|Golgi apparatus|integral to membrane|lysosomal membrane|plasma membrane	anion:anion antiporter activity|secondary active sulfate transmembrane transporter activity				0	all_neural(118;0.0538)		OV - Ovarian serous cystadenocarcinoma(97;0.0344)|BRCA - Breast invasive adenocarcinoma(99;0.0908)			GTCAGGCCAGGTCCTCTGGCC	0.687		NA											7	19					0.00621372	0.00671753	1	0
KIAA0802	23255	broad.mit.edu	37	18	8825333	8825333	+	Silent	SNP	G	G	A			TCGA-CR-5249-01A-01D-1512-08	TCGA-CR-5249-10A-01D-1512-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	42bf9ca3-47d8-45ff-bccf-bda80af58d22	25a6fe65-a78b-4adc-8ce7-1bc2bc4bbf48	g.chr18:8825333G>A	uc002knr.2	+	15	3967	c.3825G>A	c.(3823-3825)GAG>GAA	p.E1275E	KIAA0802_uc002knq.2_Silent_p.E1234E|KIAA0802_uc002kns.2_Silent_p.E615E	NM_015210	NP_056025	Q9Y4B5	CC165_HUMAN	hypothetical protein LOC23255	1585											0						ACAGCCTGGAGATGTCCAAGA	0.617		NA											20	51					0	0	0	0
PNPLA6	10908	broad.mit.edu	37	19	7605584	7605584	+	Silent	SNP	G	G	A			TCGA-CR-5249-01A-01D-1512-08	TCGA-CR-5249-10A-01D-1512-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	42bf9ca3-47d8-45ff-bccf-bda80af58d22	25a6fe65-a78b-4adc-8ce7-1bc2bc4bbf48	g.chr19:7605584G>A	uc010xjq.1	+	8	1005	c.810G>A	c.(808-810)CTG>CTA	p.L270L	PNPLA6_uc002mgq.1_Silent_p.L222L|PNPLA6_uc010xjp.1_Silent_p.L222L|PNPLA6_uc002mgr.1_Silent_p.L222L|PNPLA6_uc002mgs.2_Silent_p.L261L	NM_006702	NP_006693	Q8IY17	PLPL6_HUMAN	neuropathy target esterase isoform b	261	cNMP 1.|Cytoplasmic (Potential).				cell death|lipid catabolic process|phosphatidylcholine metabolic process	endoplasmic reticulum membrane|integral to membrane	lysophospholipase activity			ovary(3)	3						TCAGCATCCTGGATGTCATCA	0.587		NA											5	127					0	0	0	0
ILF3	3609	broad.mit.edu	37	19	10793296	10793296	+	Silent	SNP	G	G	A			TCGA-CR-5249-01A-01D-1512-08	TCGA-CR-5249-10A-01D-1512-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	42bf9ca3-47d8-45ff-bccf-bda80af58d22	25a6fe65-a78b-4adc-8ce7-1bc2bc4bbf48	g.chr19:10793296G>A	uc002mpn.2	+	13	1781	c.1464G>A	c.(1462-1464)GCG>GCA	p.A488A	ILF3_uc002mpm.2_Silent_p.A488A|ILF3_uc002mpl.2_Silent_p.A488A|ILF3_uc002mpk.2_Silent_p.A488A|ILF3_uc010xli.1_Silent_p.A86A|ILF3_uc002mpo.2_Silent_p.A488A|ILF3_uc002mpp.2_Silent_p.A309A	NM_012218	NP_036350	Q12906	ILF3_HUMAN	interleukin enhancer binding factor 3 isoform a	488					M phase|negative regulation of transcription, DNA-dependent|positive regulation of transcription, DNA-dependent|transcription, DNA-dependent	mitochondrion|nucleolus|ribonucleoprotein complex	DNA binding|double-stranded RNA binding|protein binding|protein binding			ovary(3)	3			Epithelial(33;6.86e-06)|all cancers(31;1.65e-05)			AGACCGAGGCGAAGCCAGCAG	0.642		NA											6	51					0	0	0	0
QTRT1	81890	broad.mit.edu	37	19	10823854	10823854	+	Missense_Mutation	SNP	C	C	T			TCGA-CR-5249-01A-01D-1512-08	TCGA-CR-5249-10A-01D-1512-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	42bf9ca3-47d8-45ff-bccf-bda80af58d22	25a6fe65-a78b-4adc-8ce7-1bc2bc4bbf48	g.chr19:10823854C>T	uc002mpr.2	+	10	1145	c.1120C>T	c.(1120-1122)CGG>TGG	p.R374W	DNM2_uc010dxk.2_RNA	NM_031209	NP_112486	Q9BXR0	TGT_HUMAN	queuine tRNA-ribosyltransferase 1	374					queuosine biosynthetic process	mitochondrion|nucleus|ribosome	metal ion binding|queuine tRNA-ribosyltransferase activity			skin(1)	1			Epithelial(33;1.55e-05)|all cancers(31;3.42e-05)			GGACTTCGTGCGGGACTTCAT	0.657		NA											20	97					0	0	0	0
CACNA1A	773	broad.mit.edu	37	19	13368242	13368242	+	Silent	SNP	G	G	T			TCGA-CR-5249-01A-01D-1512-08	TCGA-CR-5249-10A-01D-1512-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	42bf9ca3-47d8-45ff-bccf-bda80af58d22	25a6fe65-a78b-4adc-8ce7-1bc2bc4bbf48	g.chr19:13368242G>T	uc010dze.2	-	28	4751	c.4515C>A	c.(4513-4515)ATC>ATA	p.I1505I	CACNA1A_uc010xnd.1_Silent_p.I210I|CACNA1A_uc002mwx.3_Silent_p.I210I|CACNA1A_uc010dzc.2_Silent_p.I1030I|CACNA1A_uc002mwy.3_Silent_p.I1504I|CACNA1A_uc010xne.1_Silent_p.I1033I|CACNA1A_uc002mwv.3_Silent_p.I21I	NM_001127221	NP_001120693	O00555	CAC1A_HUMAN	calcium channel, alpha 1A subunit isoform 3	1505	III.|Helical; Name=S6 of repeat III; (Potential).				cell death|elevation of cytosolic calcium ion concentration|energy reserve metabolic process|membrane depolarization|regulation of insulin secretion	cytoplasm|nucleus	syntaxin binding			large_intestine(2)	2			OV - Ovarian serous cystadenocarcinoma(19;5.07e-21)		Bepridil(DB01244)|Cinnarizine(DB00568)|Loperamide(DB00836)|Nisoldipine(DB00401)|Pregabalin(DB00230)	AGGCCACAAAGATATTGACAA	0.502		NA											14	31					2.62e-11	2.96e-11	1	0
ZNF569	148266	broad.mit.edu	37	19	37904081	37904081	+	Silent	SNP	G	G	T			TCGA-CR-5249-01A-01D-1512-08	TCGA-CR-5249-10A-01D-1512-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	42bf9ca3-47d8-45ff-bccf-bda80af58d22	25a6fe65-a78b-4adc-8ce7-1bc2bc4bbf48	g.chr19:37904081G>T	uc002ogi.2	-	6	2037	c.1479C>A	c.(1477-1479)CCC>CCA	p.P493P	ZNF569_uc002ogh.2_Silent_p.P334P|ZNF569_uc002ogj.2_Silent_p.P517P	NM_152484	NP_689697	Q5MCW4	ZN569_HUMAN	zinc finger protein 569	493					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			breast(2)|skin(1)	3			COAD - Colon adenocarcinoma(19;0.114)|Colorectal(19;0.177)			TGCATTCATAGGGTTTCTCTC	0.353		NA											31	92					2.66e-16	3.04e-16	1	0
GYS1	2997	broad.mit.edu	37	19	49494659	49494659	+	Missense_Mutation	SNP	G	G	A			TCGA-CR-5249-01A-01D-1512-08	TCGA-CR-5249-10A-01D-1512-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	42bf9ca3-47d8-45ff-bccf-bda80af58d22	25a6fe65-a78b-4adc-8ce7-1bc2bc4bbf48	g.chr19:49494659G>A	uc002plp.2	-	2	441	c.200C>T	c.(199-201)CCG>CTG	p.P67L	GYS1_uc010xzy.1_Intron|GYS1_uc010emm.2_Missense_Mutation_p.P67L|GYS1_uc010xzz.1_Intron|GYS1_uc010yaa.1_Intron|RUVBL2_uc002plq.1_5'Flank|RUVBL2_uc010yab.1_5'Flank|RUVBL2_uc002plr.1_5'Flank|RUVBL2_uc002pls.1_5'Flank|RUVBL2_uc010emn.1_5'Flank	NM_002103	NP_002094	P13807	GYS1_HUMAN	glycogen synthase 1 (muscle) isoform 1	67					glucose metabolic process|glycogen biosynthetic process	cytosol	glycogen (starch) synthase activity|protein binding			ovary(2)	2		all_lung(116;4.89e-05)|Lung NSC(112;8.3e-05)|all_epithelial(76;8.64e-05)|all_neural(266;0.0506)|Ovarian(192;0.113)		OV - Ovarian serous cystadenocarcinoma(262;0.000164)|all cancers(93;0.000226)|GBM - Glioblastoma multiforme(486;0.00561)|Epithelial(262;0.0286)		CTCCGTGTACGGCCCCACCAG	0.637		NA											6	291					0	0	0	0
ZNF814	730051	broad.mit.edu	37	19	58385748	58385748	+	Missense_Mutation	SNP	G	G	A	rs145250945		TCGA-CR-5249-01A-01D-1512-08	TCGA-CR-5249-10A-01D-1512-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	42bf9ca3-47d8-45ff-bccf-bda80af58d22	25a6fe65-a78b-4adc-8ce7-1bc2bc4bbf48	g.chr19:58385748G>A	uc002qqo.2	-	3	1282	c.1010C>T	c.(1009-1011)GCT>GTT	p.A337V	ZNF814_uc002qqk.2_Intron|ZNF814_uc010yhl.1_Intron	NM_001144989	NP_001138461	B7Z6K7	ZN814_HUMAN	zinc finger protein 814	337	C2H2-type 5.				regulation of transcription, DNA-dependent	intracellular	nucleic acid binding|zinc ion binding				0						ACTGAAGCTAGCATATTTGCT	0.353		NA											3	11					0	0	0	0
EMX1	2016	broad.mit.edu	37	2	73161022	73161022	+	Missense_Mutation	SNP	G	G	T			TCGA-CR-5249-01A-01D-1512-08	TCGA-CR-5249-10A-01D-1512-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	42bf9ca3-47d8-45ff-bccf-bda80af58d22	25a6fe65-a78b-4adc-8ce7-1bc2bc4bbf48	g.chr2:73161022G>T	uc002sin.1	+	3	1190	c.812G>T	c.(811-813)CGG>CTG	p.R271L	EMX1_uc002sim.1_3'UTR	NM_004097	NP_004088	Q04741	EMX1_HUMAN	empty spiracles homolog 1	238						nucleus	sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity				0						CACATCAACCGGTGGCGCATT	0.577		NA											3	84					0.004672	0.00507826	1	0
SNRNP200	23020	broad.mit.edu	37	2	96970571	96970571	+	Silent	SNP	G	G	A			TCGA-CR-5249-01A-01D-1512-08	TCGA-CR-5249-10A-01D-1512-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	42bf9ca3-47d8-45ff-bccf-bda80af58d22	25a6fe65-a78b-4adc-8ce7-1bc2bc4bbf48	g.chr2:96970571G>A	uc002svu.2	-	2	167	c.81C>T	c.(79-81)CTC>CTT	p.L27L		NM_014014	NP_054733	O75643	U520_HUMAN	activating signal cointegrator 1 complex subunit	27						catalytic step 2 spliceosome|nucleoplasm|U5 snRNP	ATP binding|ATP-dependent helicase activity|nucleic acid binding|protein binding			ovary(5)|skin(4)|large_intestine(1)	10						TCCGGTCAATGAGAGAACGGT	0.507		NA											22	45					0	0	0	0
NCOA6	23054	broad.mit.edu	37	20	33345055	33345055	+	Missense_Mutation	SNP	T	T	C			TCGA-CR-5249-01A-01D-1512-08	TCGA-CR-5249-10A-01D-1512-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	42bf9ca3-47d8-45ff-bccf-bda80af58d22	25a6fe65-a78b-4adc-8ce7-1bc2bc4bbf48	g.chr20:33345055T>C	uc002xav.2	-	8	4067	c.1496A>G	c.(1495-1497)CAG>CGG	p.Q499R	NCOA6_uc002xaw.2_Missense_Mutation_p.Q499R|NCOA6_uc010gew.1_Missense_Mutation_p.Q456R	NM_014071	NP_054790	Q14686	NCOA6_HUMAN	nuclear receptor coactivator 6	499	TBP/GTF2A-binding region.|NCOA1-binding region.|Gln-rich.|CREBBP-binding region.				brain development|cellular lipid metabolic process|DNA recombination|DNA repair|DNA replication|estrogen receptor signaling pathway|glucocorticoid receptor signaling pathway|heart development|myeloid cell differentiation|positive regulation of transcription from RNA polymerase II promoter|response to hormone stimulus|transcription initiation from RNA polymerase II promoter	transcription factor complex	chromatin binding|enzyme binding|estrogen receptor binding|ligand-dependent nuclear receptor transcription coactivator activity|retinoid X receptor binding|thyroid hormone receptor binding			ovary(3)|breast(3)|central_nervous_system(1)	7						CTGTGGCCCCTGGTTTGGTGG	0.488		NA											6	273					0	0	0	0
KCNB1	3745	broad.mit.edu	37	20	48098552	48098552	+	Missense_Mutation	SNP	G	G	A			TCGA-CR-5249-01A-01D-1512-08	TCGA-CR-5249-10A-01D-1512-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	42bf9ca3-47d8-45ff-bccf-bda80af58d22	25a6fe65-a78b-4adc-8ce7-1bc2bc4bbf48	g.chr20:48098552G>A	uc002xur.1	-	1	630	c.466C>T	c.(466-468)CGG>TGG	p.R156W	KCNB1_uc002xus.1_Missense_Mutation_p.R156W	NM_004975	NP_004966	Q14721	KCNB1_HUMAN	potassium voltage-gated channel, Shab-related	156	Cytoplasmic (Potential).				energy reserve metabolic process|regulation of insulin secretion	voltage-gated potassium channel complex	protein binding|voltage-gated potassium channel activity			pancreas(1)|skin(1)	2			BRCA - Breast invasive adenocarcinoma(12;0.000405)|COAD - Colon adenocarcinoma(4;0.14)|Colorectal(8;0.166)			TCCCGCTCCCGTAGGGTCTCG	0.582		NA											46	117					0	0	0	0
ZGPAT	84619	broad.mit.edu	37	20	62340307	62340307	+	Silent	SNP	C	C	T			TCGA-CR-5249-01A-01D-1512-08	TCGA-CR-5249-10A-01D-1512-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	42bf9ca3-47d8-45ff-bccf-bda80af58d22	25a6fe65-a78b-4adc-8ce7-1bc2bc4bbf48	g.chr20:62340307C>T	uc002ygk.2	+	2	553	c.375C>T	c.(373-375)GAC>GAT	p.D125D	ARFRP1_uc002yga.2_5'Flank|ARFRP1_uc002ygc.2_5'Flank|ARFRP1_uc002ygh.3_5'Flank|ARFRP1_uc011abf.1_5'Flank|ARFRP1_uc011abg.1_5'Flank|ARFRP1_uc002yge.2_5'Flank|ARFRP1_uc002ygd.2_5'Flank|ARFRP1_uc002ygf.2_5'Flank|ARFRP1_uc002ygg.2_5'Flank|ARFRP1_uc011abh.1_5'Flank|ZGPAT_uc002ygi.2_Silent_p.D125D|ZGPAT_uc002ygj.2_Silent_p.D125D|ZGPAT_uc010gkk.1_Intron|ZGPAT_uc010gkl.1_Silent_p.D125D|ZGPAT_uc002ygm.2_Silent_p.D125D|ZGPAT_uc002ygn.3_RNA	NM_032527	NP_115916	Q8N5A5	ZGPAT_HUMAN	zinc finger, CCCH-type with G patch domain	125	Poly-Glu.				negative regulation of epidermal growth factor receptor activity|negative regulation of transcription, DNA-dependent	nucleus	protein binding|sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity|zinc ion binding				0	all_cancers(38;1.13e-12)|all_epithelial(29;2.64e-14)|Lung NSC(23;4.79e-10)|all_lung(23;1.7e-09)					agggagaggacgaggaagagC	0.542		NA											5	70					0	0	0	0
ABCG1	9619	broad.mit.edu	37	21	43708124	43708124	+	Missense_Mutation	SNP	C	C	G			TCGA-CR-5249-01A-01D-1512-08	TCGA-CR-5249-10A-01D-1512-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	42bf9ca3-47d8-45ff-bccf-bda80af58d22	25a6fe65-a78b-4adc-8ce7-1bc2bc4bbf48	g.chr21:43708124C>G	uc002zaq.2	+	9	1205	c.1099C>G	c.(1099-1101)CTT>GTT	p.L367V	ABCG1_uc002zan.2_Missense_Mutation_p.L369V|ABCG1_uc002zam.2_Missense_Mutation_p.L345V|ABCG1_uc002zao.2_Missense_Mutation_p.L364V|ABCG1_uc002zap.2_Missense_Mutation_p.L367V|ABCG1_uc002zar.2_Missense_Mutation_p.L378V|ABCG1_uc011aev.1_Missense_Mutation_p.L378V|ABCG1_uc010gpb.1_5'UTR	NM_004915	NP_004906	P45844	ABCG1_HUMAN	ATP-binding cassette sub-family G member 1	367	Cytoplasmic (Potential).				amyloid precursor protein catabolic process|cholesterol efflux|cholesterol homeostasis|cholesterol metabolic process|detection of hormone stimulus|high-density lipoprotein particle remodeling|intracellular cholesterol transport|lipoprotein metabolic process|low-density lipoprotein particle remodeling|negative regulation of cholesterol storage|negative regulation of macrophage derived foam cell differentiation|phospholipid efflux|phospholipid homeostasis|positive regulation of cholesterol biosynthetic process|regulation of cholesterol esterification|regulation of transcription, DNA-dependent|response to lipid|reverse cholesterol transport	endoplasmic reticulum membrane|external side of plasma membrane|Golgi membrane|recycling endosome	ADP binding|ATP binding|cholesterol transporter activity|glycoprotein transporter activity|phospholipid transporter activity|protein heterodimerization activity|protein homodimerization activity|sterol-transporting ATPase activity|toxin transporter activity			ovary(2)|central_nervous_system(1)	3					Adenosine triphosphate(DB00171)	GAACCCTTTTCTTTGGCACCG	0.567		NA											17	238					0	0	0	0
SLITRK3	22865	broad.mit.edu	37	3	164906486	164906486	+	Silent	SNP	A	A	G			TCGA-CR-5249-01A-01D-1512-08	TCGA-CR-5249-10A-01D-1512-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	42bf9ca3-47d8-45ff-bccf-bda80af58d22	25a6fe65-a78b-4adc-8ce7-1bc2bc4bbf48	g.chr3:164906486A>G	uc003fej.3	-	2	2577	c.2133T>C	c.(2131-2133)GAT>GAC	p.D711D	SLITRK3_uc003fek.2_Silent_p.D711D	NM_014926	NP_055741	O94933	SLIK3_HUMAN	slit and trk like 3 protein precursor	711	Cytoplasmic (Potential).					integral to membrane				ovary(6)|skin(3)|pancreas(1)	10						cacctccaccaTCCTCAAACA	0.458		NA								HNSCC(40;0.11)			14	72					0	0	0	0
PIK3CA	5290	broad.mit.edu	37	3	178936082	178936082	+	Missense_Mutation	SNP	G	G	A	rs121913273		TCGA-CR-5249-01A-01D-1512-08	TCGA-CR-5249-10A-01D-1512-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	42bf9ca3-47d8-45ff-bccf-bda80af58d22	25a6fe65-a78b-4adc-8ce7-1bc2bc4bbf48	g.chr3:178936082G>A	uc003fjk.2	+	10	1781	c.1624G>A	c.(1624-1626)GAA>AAA	p.E542K		NM_006218	NP_006209	P42336	PK3CA_HUMAN	phosphoinositide-3-kinase, catalytic, alpha	542	PI3K helical.		E -> V (in cancer).|E -> K (in KERSEB; shows an increase in lipid kinase activity; oncogenic in vivo; occurs in the interface between the PI3K helical domain and the nSH2 (N-terminal SH2) region of the p85 regulatory subunit and may reduce the inhibitory effect of p85; requires interaction with RAS to induce cellular transformation).|E -> Q (in cancer).		epidermal growth factor receptor signaling pathway|fibroblast growth factor receptor signaling pathway|insulin receptor signaling pathway|leukocyte migration|nerve growth factor receptor signaling pathway|phosphatidylinositol-mediated signaling|platelet activation|T cell costimulation|T cell receptor signaling pathway		1-phosphatidylinositol-3-kinase activity|ATP binding|phosphatidylinositol-4,5-bisphosphate 3-kinase activity	p.E542K(481)|p.E542V(8)|p.E542Q(6)|p.E542G(1)		breast(1564)|large_intestine(776)|endometrium(246)|urinary_tract(195)|ovary(141)|skin(112)|stomach(98)|thyroid(77)|central_nervous_system(69)|lung(65)|upper_aerodigestive_tract(58)|haematopoietic_and_lymphoid_tissue(27)|cervix(25)|biliary_tract(22)|liver(20)|oesophagus(17)|pancreas(11)|penis(8)|pituitary(8)|autonomic_ganglia(4)|prostate(3)|kidney(2)|meninges(1)|eye(1)|NS(1)|soft_tissue(1)|bone(1)	3553	all_cancers(143;1.19e-17)|Ovarian(172;0.00769)|Breast(254;0.155)		OV - Ovarian serous cystadenocarcinoma(80;9.59e-28)|GBM - Glioblastoma multiforme(14;0.003)|BRCA - Breast invasive adenocarcinoma(182;0.0282)			TCCTCTCTCTGAAATCACTGA	0.333	E542K(SW948_LARGE_INTESTINE)|E542K(T84_LARGE_INTESTINE)|E542K(CAL51_BREAST)|E542K(JHUEM1_ENDOMETRIUM)|E542K(NCIH1341_LUNG)|E542K(VMCUB1_URINARY_TRACT)|E542K(BT483_BREAST)|E542K(HGC27_STOMACH)|E542K(IM95_STOMACH)	57	Mis		colorectal|gastric|gliobastoma|breast					HNSCC(19;0.045)|TSP Lung(28;0.18)			139	67					0	0	0	0
IQCG	84223	broad.mit.edu	37	3	197665623	197665623	+	Missense_Mutation	SNP	G	G	A			TCGA-CR-5249-01A-01D-1512-08	TCGA-CR-5249-10A-01D-1512-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	42bf9ca3-47d8-45ff-bccf-bda80af58d22	25a6fe65-a78b-4adc-8ce7-1bc2bc4bbf48	g.chr3:197665623G>A	uc003fyo.2	-	4	457	c.311C>T	c.(310-312)ACG>ATG	p.T104M	IQCG_uc003fyn.2_Missense_Mutation_p.T6M|IQCG_uc003fyp.2_Missense_Mutation_p.T104M|IQCG_uc003fyq.3_Missense_Mutation_p.T104M	NM_001134435	NP_001127907	Q9H095	IQCG_HUMAN	IQ motif containing G	104											0	all_cancers(143;1.15e-09)|Ovarian(172;0.0418)|Breast(254;0.0976)		Epithelial(36;7.19e-24)|all cancers(36;3.34e-22)|OV - Ovarian serous cystadenocarcinoma(49;1.1e-18)|LUSC - Lung squamous cell carcinoma(58;6.94e-07)|Lung(62;9.92e-07)	GBM - Glioblastoma multiforme(93;0.149)		GTCTAGATTCGTTCCTTCTAG	0.358		NA											26	819					0	0	0	0
THAP9	79725	broad.mit.edu	37	4	83827690	83827690	+	Missense_Mutation	SNP	A	A	G			TCGA-CR-5249-01A-01D-1512-08	TCGA-CR-5249-10A-01D-1512-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	42bf9ca3-47d8-45ff-bccf-bda80af58d22	25a6fe65-a78b-4adc-8ce7-1bc2bc4bbf48	g.chr4:83827690A>G	uc003hnt.2	+	3	609	c.490A>G	c.(490-492)AAG>GAG	p.K164E	THAP9_uc003hns.1_Missense_Mutation_p.K20E|THAP9_uc003hnu.1_RNA|THAP9_uc003hnv.2_5'UTR	NM_024672	NP_078948	Q9H5L6	THAP9_HUMAN	THAP domain containing 9	164							DNA binding|metal ion binding			ovary(2)|large_intestine(1)|central_nervous_system(1)|pancreas(1)	5		Hepatocellular(203;0.114)				GATGATCAAGAAGAGAAAGGG	0.403		NA											49	117					0	0	0	0
CCDC110	256309	broad.mit.edu	37	4	186379447	186379447	+	Missense_Mutation	SNP	C	C	T			TCGA-CR-5249-01A-01D-1512-08	TCGA-CR-5249-10A-01D-1512-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	42bf9ca3-47d8-45ff-bccf-bda80af58d22	25a6fe65-a78b-4adc-8ce7-1bc2bc4bbf48	g.chr4:186379447C>T	uc003ixu.3	-	6	2370	c.2294G>A	c.(2293-2295)CGG>CAG	p.R765Q	CCDC110_uc003ixv.3_Missense_Mutation_p.R728Q|CCDC110_uc011ckt.1_Missense_Mutation_p.R765Q	NM_152775	NP_689988	Q8TBZ0	CC110_HUMAN	coiled-coil domain containing 110 isoform a	765	Potential.					nucleus				central_nervous_system(1)	1		all_lung(41;1.3e-11)|Lung NSC(41;2.25e-11)|Melanoma(20;7.86e-05)|Renal(120;0.0246)|Hepatocellular(41;0.0268)|Prostate(90;0.0283)|Colorectal(36;0.0381)|all_hematologic(60;0.0749)		OV - Ovarian serous cystadenocarcinoma(60;1.13e-10)|BRCA - Breast invasive adenocarcinoma(30;8.01e-05)|GBM - Glioblastoma multiforme(59;0.00014)|STAD - Stomach adenocarcinoma(60;0.000777)|LUSC - Lung squamous cell carcinoma(40;0.00921)|COAD - Colon adenocarcinoma(29;0.0105)|READ - Rectum adenocarcinoma(43;0.164)		TTGAAGATGCCGCATCTCAAA	0.308		NA											18	46					0	0	0	0
CHD1	1105	broad.mit.edu	37	5	98237004	98237004	+	Missense_Mutation	SNP	G	G	C			TCGA-CR-5249-01A-01D-1512-08	TCGA-CR-5249-10A-01D-1512-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	42bf9ca3-47d8-45ff-bccf-bda80af58d22	25a6fe65-a78b-4adc-8ce7-1bc2bc4bbf48	g.chr5:98237004G>C	uc003knf.2	-	5	621	c.473C>G	c.(472-474)TCT>TGT	p.S158C		NM_001270	NP_001261	O14646	CHD1_HUMAN	chromodomain helicase DNA binding protein 1	158					regulation of transcription from RNA polymerase II promoter|transcription, DNA-dependent	cytoplasm|nucleus	ATP binding|ATP-dependent DNA helicase activity|DNA binding|methylated histone residue binding			lung(2)|ovary(1)|breast(1)|pancreas(1)	5		all_cancers(142;5.36e-08)|all_epithelial(76;6.97e-11)|Lung NSC(167;0.000693)|Prostate(80;0.000986)|all_lung(232;0.00119)|Ovarian(225;0.024)|Colorectal(57;0.117)		COAD - Colon adenocarcinoma(37;0.0717)	Epirubicin(DB00445)	ACCAGACTGAGATGGAGATCC	0.348		NA											52	176					0	0	0	0
C6orf58	352999	broad.mit.edu	37	6	127911331	127911331	+	Silent	SNP	A	A	G			TCGA-CR-5249-01A-01D-1512-08	TCGA-CR-5249-10A-01D-1512-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	42bf9ca3-47d8-45ff-bccf-bda80af58d22	25a6fe65-a78b-4adc-8ce7-1bc2bc4bbf48	g.chr6:127911331A>G	uc003qbh.2	+	5	786	c.774A>G	c.(772-774)AGA>AGG	p.R258R		NM_001010905	NP_001010905	Q6P5S2	CF058_HUMAN	hypothetical protein LOC352999 precursor	258						extracellular region					0				GBM - Glioblastoma multiforme(226;0.0405)|all cancers(137;0.156)		CCTTGATTAGATCATATAAGT	0.408		NA											68	145					0	0	0	0
SYNE1	23345	broad.mit.edu	37	6	152461285	152461285	+	Nonsense_Mutation	SNP	G	G	A			TCGA-CR-5249-01A-01D-1512-08	TCGA-CR-5249-10A-01D-1512-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	42bf9ca3-47d8-45ff-bccf-bda80af58d22	25a6fe65-a78b-4adc-8ce7-1bc2bc4bbf48	g.chr6:152461285G>A	uc010kiw.2	-	140	25860	c.25258C>T	c.(25258-25260)CGA>TGA	p.R8420*	SYNE1_uc010kiv.2_Nonsense_Mutation_p.R2944*|SYNE1_uc003qos.3_Nonsense_Mutation_p.R2944*|SYNE1_uc003qot.3_Nonsense_Mutation_p.R8372*|SYNE1_uc003qou.3_Nonsense_Mutation_p.R8420*|SYNE1_uc003qop.3_Nonsense_Mutation_p.R605*|SYNE1_uc011eez.1_Nonsense_Mutation_p.R622*|SYNE1_uc003qoq.3_Nonsense_Mutation_p.R622*|SYNE1_uc003qor.3_Nonsense_Mutation_p.R1343*	NM_182961	NP_892006	Q8NF91	SYNE1_HUMAN	spectrin repeat containing, nuclear envelope 1	8420	Cytoplasmic (Potential).				cell death|cytoskeletal anchoring at nuclear membrane|Golgi organization|muscle cell differentiation|nuclear matrix anchoring at nuclear membrane	cytoskeleton|Golgi apparatus|integral to membrane|nuclear outer membrane|postsynaptic membrane|sarcomere|SUN-KASH complex	actin binding|lamin binding			central_nervous_system(15)|upper_aerodigestive_tract(9)|ovary(8)|skin(6)|large_intestine(5)|pancreas(2)	45		Ovarian(120;0.0955)	BRCA - Breast invasive adenocarcinoma(37;0.243)	OV - Ovarian serous cystadenocarcinoma(155;2.24e-10)		AGCTCCCATCGGTCAATCACA	0.453		NA								HNSCC(10;0.0054)			26	85					0	0	0	0
DNAH11	8701	broad.mit.edu	37	7	21598482	21598482	+	Missense_Mutation	SNP	A	A	T			TCGA-CR-5249-01A-01D-1512-08	TCGA-CR-5249-10A-01D-1512-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	42bf9ca3-47d8-45ff-bccf-bda80af58d22	25a6fe65-a78b-4adc-8ce7-1bc2bc4bbf48	g.chr7:21598482A>T	uc003svc.2	+	3	589	c.558A>T	c.(556-558)CAA>CAT	p.Q186H		NM_003777	NP_003768	Q96DT5	DYH11_HUMAN	dynein, axonemal, heavy chain 11	186	Stem (By similarity).				microtubule-based movement	axonemal dynein complex|cilium axoneme|cytoplasm|microtubule	ATP binding|ATPase activity|microtubule motor activity			ovary(8)|large_intestine(3)|pancreas(3)|central_nervous_system(1)	15						TTACTTCACAAGATATGGAAT	0.333		NA							Kartagener_syndrome				4	26					0	0	0	0
FZD1	8321	broad.mit.edu	37	7	90895605	90895605	+	Silent	SNP	C	C	T			TCGA-CR-5249-01A-01D-1512-08	TCGA-CR-5249-10A-01D-1512-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	42bf9ca3-47d8-45ff-bccf-bda80af58d22	25a6fe65-a78b-4adc-8ce7-1bc2bc4bbf48	g.chr7:90895605C>T	uc003ula.2	+	1	1823	c.1410C>T	c.(1408-1410)GGC>GGT	p.G470G		NM_003505	NP_003496	Q9UP38	FZD1_HUMAN	frizzled 1 precursor	470	Extracellular (Potential).				autocrine signaling|axonogenesis|brain development|canonical Wnt receptor signaling pathway involved in mesenchymal stem cell differentiation|canonical Wnt receptor signaling pathway involved in osteoblast differentiation|embryo development|epithelial cell differentiation|G-protein signaling, coupled to cGMP nucleotide second messenger|gonad development|lung alveolus development|negative regulation of BMP signaling pathway|negative regulation of canonical Wnt receptor signaling pathway|positive regulation of sequence-specific DNA binding transcription factor activity|positive regulation of transcription, DNA-dependent|response to drug|vasculature development|Wnt receptor signaling pathway, calcium modulating pathway	apical part of cell|cell surface|cytoplasm|integral to membrane|neuron projection membrane	G-protein coupled receptor activity|PDZ domain binding|receptor binding|Wnt receptor activity|Wnt-protein binding				0	all_cancers(62;3.1e-10)|all_epithelial(64;1.66e-08)|Breast(17;0.000635)|Lung NSC(181;0.153)|all_lung(186;0.154)|all_hematologic(106;0.215)		STAD - Stomach adenocarcinoma(171;0.0134)			AGGTGGACGGCGATGTGCTGA	0.622		NA											5	209					0	0	0	0
C9orf102	375748	broad.mit.edu	37	9	98740378	98740378	+	Missense_Mutation	SNP	C	C	G			TCGA-CR-5249-01A-01D-1512-08	TCGA-CR-5249-10A-01D-1512-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	42bf9ca3-47d8-45ff-bccf-bda80af58d22	25a6fe65-a78b-4adc-8ce7-1bc2bc4bbf48	g.chr9:98740378C>G	uc004avu.2	+	12	2491	c.1246C>G	c.(1246-1248)CAG>GAG	p.Q416E	uc010msa.1_Missense_Mutation_p.Q106E|uc011lun.1_Missense_Mutation_p.Q106E			Q5T890	RAD26_HUMAN	Homo sapiens cDNA, FLJ97452.	Error:Variant_position_missing_in_Q5T890_after_alignment					DNA repair	nucleus	ATP binding|ATP-dependent helicase activity|DNA binding				0		Acute lymphoblastic leukemia(62;0.0559)				TCACTCAAACCAGAATGTAAT	0.388		NA											20	67					0	0	0	0
PDHA1	5160	broad.mit.edu	37	X	19369427	19369427	+	Missense_Mutation	SNP	G	G	A			TCGA-CR-5249-01A-01D-1512-08	TCGA-CR-5249-10A-01D-1512-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	42bf9ca3-47d8-45ff-bccf-bda80af58d22	25a6fe65-a78b-4adc-8ce7-1bc2bc4bbf48	g.chrX:19369427G>A	uc004czg.3	+	4	465	c.320G>A	c.(319-321)GGC>GAC	p.G107D	PDHA1_uc004czh.3_Missense_Mutation_p.G142D|PDHA1_uc011mjc.1_Missense_Mutation_p.G111D|PDHA1_uc011mjd.1_Missense_Mutation_p.G104D|PDHA1_uc010nfk.2_Missense_Mutation_p.G104D	NM_000284	NP_000275	P08559	ODPA_HUMAN	pyruvate dehydrogenase E1 alpha 1 precursor	107					glycolysis|pyruvate metabolic process|regulation of acetyl-CoA biosynthetic process from pyruvate	mitochondrial matrix	protein binding|pyruvate dehydrogenase (acetyl-transferring) activity			ovary(1)	1	Hepatocellular(33;0.183)				NADH(DB00157)	CTGGAGGCCGGCATCAACCCC	0.507		NA											6	222					0	0	0	0
PCDH11X	27328	broad.mit.edu	37	X	91642836	91642836	+	Missense_Mutation	SNP	C	C	G			TCGA-CR-5249-01A-01D-1512-08	TCGA-CR-5249-10A-01D-1512-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	42bf9ca3-47d8-45ff-bccf-bda80af58d22	25a6fe65-a78b-4adc-8ce7-1bc2bc4bbf48	g.chrX:91642836C>G	uc004efk.1	+	5	4092	c.3247C>G	c.(3247-3249)CAT>GAT	p.H1083D	PCDH11X_uc004efl.1_Missense_Mutation_p.H1073D|PCDH11X_uc004efo.1_Missense_Mutation_p.H1046D|PCDH11X_uc010nmv.1_Intron|PCDH11X_uc004efm.1_Missense_Mutation_p.H1083D|PCDH11X_uc004efn.1_Missense_Mutation_p.H1073D	NM_032968	NP_116750	Q9BZA7	PC11X_HUMAN	protocadherin 11 X-linked isoform c	1083	Cytoplasmic (Potential).				homophilic cell adhesion	integral to plasma membrane	calcium ion binding			large_intestine(2)	2						CAGCACATCTCATGGCCTGCC	0.552		NA											38	134					0	0	0	0
WDR44	54521	broad.mit.edu	37	X	117532358	117532358	+	Missense_Mutation	SNP	C	C	T			TCGA-CR-5249-01A-01D-1512-08	TCGA-CR-5249-10A-01D-1512-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	42bf9ca3-47d8-45ff-bccf-bda80af58d22	25a6fe65-a78b-4adc-8ce7-1bc2bc4bbf48	g.chrX:117532358C>T	uc004eqn.2	+	8	1624	c.1199C>T	c.(1198-1200)GCG>GTG	p.A400V	WDR44_uc004eqo.2_Missense_Mutation_p.A400V|WDR44_uc011mtr.1_Missense_Mutation_p.A375V|WDR44_uc010nqi.2_Missense_Mutation_p.A110V	NM_019045	NP_061918	Q5JSH3	WDR44_HUMAN	WD repeat domain 44 protein	400						cytosol|endosome membrane|Golgi apparatus|perinuclear region of cytoplasm				lung(2)|upper_aerodigestive_tract(1)|ovary(1)|pancreas(1)	5						AGTAATGACGCGGCACAGTCA	0.358		NA											36	95					0	0	0	0
LAX1	54900	broad.mit.edu	37	1	203743036	203743038	+	In_Frame_Del	DEL	ACA	ACA	-			TCGA-CR-5249-01A-01D-1512-08	TCGA-CR-5249-10A-01D-1512-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	42bf9ca3-47d8-45ff-bccf-bda80af58d22	25a6fe65-a78b-4adc-8ce7-1bc2bc4bbf48	g.chr1:203743036_203743038delACA	uc001haa.2	+	5	834_836	c.424_426delACA	c.(424-426)ACAdel	p.T142del	LAX1_uc010pql.1_In_Frame_Del_p.T126del|LAX1_uc001hab.2_In_Frame_Del_p.T66del	NM_017773	NP_060243	Q8IWV1	LAX1_HUMAN	lymphocyte transmembrane adaptor 1 isoform a	142	Cytoplasmic (Potential).				B cell activation|immune response|inactivation of MAPK activity|intracellular signal transduction|negative regulation of T cell activation	Golgi apparatus|integral to membrane|plasma membrane	protein kinase binding|SH2 domain binding			central_nervous_system(2)	2	all_cancers(21;0.0915)		BRCA - Breast invasive adenocarcinoma(75;0.109)			CCAGGAGCATACAGCCCACATCC	0.527		NA											19	73	---	---	---	---	NA	NA	NA	NA
HELLS	3070	broad.mit.edu	37	10	96348062	96348062	+	Frame_Shift_Del	DEL	T	T	-			TCGA-CR-5249-01A-01D-1512-08	TCGA-CR-5249-10A-01D-1512-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	42bf9ca3-47d8-45ff-bccf-bda80af58d22	25a6fe65-a78b-4adc-8ce7-1bc2bc4bbf48	g.chr10:96348062delT	uc001kjt.2	+	13	1508	c.1403delT	c.(1402-1404)GTTfs	p.V468fs	HELLS_uc001kjs.2_Frame_Shift_Del_p.V452fs|HELLS_uc009xul.2_Frame_Shift_Del_p.V370fs|HELLS_uc009xum.2_Frame_Shift_Del_p.V338fs|HELLS_uc009xun.2_Frame_Shift_Del_p.V344fs|HELLS_uc009xuo.2_Frame_Shift_Del_p.V514fs|HELLS_uc001kju.2_Frame_Shift_Del_p.V107fs|HELLS_uc009xup.2_RNA|HELLS_uc009xuq.2_Frame_Shift_Del_p.V330fs|HELLS_uc009xur.2_RNA	NM_018063	NP_060533	Q9NRZ9	HELLS_HUMAN	helicase, lymphoid-specific	468					cell division|centromeric heterochromatin formation|lymphocyte proliferation|maintenance of DNA methylation|methylation-dependent chromatin silencing|mitosis|transcription, DNA-dependent	centromeric heterochromatin|nucleus	ATP binding|DNA binding|helicase activity			ovary(1)|kidney(1)	2		Colorectal(252;0.0429)		all cancers(201;2.13e-05)		GAAGTAGTCGTTTATGCTCCA	0.363		NA											35	82	---	---	---	---	NA	NA	NA	NA
ZNF337	26152	broad.mit.edu	37	20	25657231	25657232	+	Frame_Shift_Del	DEL	TG	TG	-			TCGA-CR-5249-01A-01D-1512-08	TCGA-CR-5249-10A-01D-1512-08	 	 	 	 	 	 	Unknown	Untested	Somatic	Unspecified	WXS	none	NA	NA	Illumina HiSeq	42bf9ca3-47d8-45ff-bccf-bda80af58d22	25a6fe65-a78b-4adc-8ce7-1bc2bc4bbf48	g.chr20:25657231_25657232delTG	uc002wva.2	-	4	1214_1215	c.692_693delCA	c.(691-693)ACAfs	p.T231fs	uc002wuz.2_RNA|ZNF337_uc010ztg.1_Frame_Shift_Del_p.T199fs|ZNF337_uc002wvb.2_Frame_Shift_Del_p.T231fs|ZNF337_uc002wvc.2_Frame_Shift_Del_p.T231fs	NM_015655	NP_056470	Q9Y3M9	ZN337_HUMAN	zinc finger protein 337	231					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding				0						ACTTCTCTCCTGTGTGTGTGTT	0.51		NA											7	184	---	---	---	---	NA	NA	NA	NA