Hugo_Symbol Entrez_Gene_Id Center NCBI_Build Chromosome Start_Position End_Position Strand Variant_Classification Variant_Type Reference_Allele Tumor_Seq_Allele1 Tumor_Seq_Allele2 dbSNP_RS dbSNP_Val_Status Tumor_Sample_Barcode Matched_Norm_Sample_Barcode Match_Norm_Seq_Allele1 Match_Norm_Seq_Allele2 Tumor_Validation_Allele1 Tumor_Validation_Allele2 Match_Norm_Validation_Allele1 Match_Norm_Validation_Allele2 Verification_Status Validation_Status Mutation_Status Sequencing_Phase Sequence_Source Validation_Method Score BAM_File Sequencer Tumor_Sample_UUID Matched_Norm_Sample_UUID chromosome_name start stop reference variant type gene_name transcript_name transcript_species transcript_source transcript_version strand transcript_status trv_type c_position amino_acid_change ucsc_cons domain all_domains deletion_substructures transcript_error NormalRefReads_WU NormalVarReads_WU NormalVAF_WU TumorRefReads_WU TumorVarReads_WU TumorVAF_WU RNARefReads_WU RNAVarReads_WU RNAVAF_WU MT-CYB 0 genome.wustl.edu 36 MT 14767 14767 + Missense_Mutation SNP T T C TCGA-AB-2802-03B-01W-0728-08 TCGA-AB-2802-11B-01W-0728-08 T T T C T T Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 18257c7e-ce2a-4dce-8bc0-db47ca8201a4 07284d3f-346f-473f-864e-5be1a95560ff MT 14767 14767 T C SNP MT-CYB ENST00000361789 human ensembl 54_36p +1 known missense c.20 p.I7T NULL superfamily_Transmembr_di-haem_cytochrome HMMPfam_Cytochrom_B_N,HMMPfam_Cytochrom_B_C,superfamily_Cytochrome_b/b6_C,superfamily_Transmembr_di-haem_cytochrome - no_stop_codon:bad_bp_length_for_coding_region 1696 44 2.53 2088 498 19.04 NA NA NA TBX15 0 genome.wustl.edu 36 1 119270684 119270684 + Missense_Mutation SNP T T A TCGA-AB-2802-03B-01W-0728-08 TCGA-AB-2802-11B-01W-0728-08 T T T A T T Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 18257c7e-ce2a-4dce-8bc0-db47ca8201a4 07284d3f-346f-473f-864e-5be1a95560ff 1 119270684 119270684 T A SNP TBX15 NM_152380.2 human genbank 54_36p -1 validated missense c.175 p.I59F 1.000 HMMPfam_T-box,HMMSmart_TBOX,superfamily_P53_like_DNA_bnd HMMPfam_T-box,HMMSmart_TBOX,superfamily_P53_like_DNA_bnd,PatternScan_TBOX_2,PatternScan_TBOX_1 - no_errors 468 7 1.47 120 54 30.68 NA NA NA TCHHL1 0 genome.wustl.edu 36 1 150324146 150324146 + Missense_Mutation SNP T T C TCGA-AB-2802-03B-01W-0728-08 TCGA-AB-2802-11B-01W-0728-08 T T T C T T Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 18257c7e-ce2a-4dce-8bc0-db47ca8201a4 07284d3f-346f-473f-864e-5be1a95560ff 1 150324146 150324146 T C SNP TCHHL1 NM_001008536.1 human genbank 54_36p -1 provisional missense c.2636 p.Q879R 0.075 NULL PatternScan_S100_CABP,HMMPfam_S_100,superfamily_SSF47473 - no_errors 743 4 0.54 142 78 35.14 NA NA NA DNMT3A 0 genome.wustl.edu 36 2 25310747 25310747 + Missense_Mutation SNP G G A TCGA-AB-2802-03B-01W-0728-08 TCGA-AB-2802-11B-01W-0728-08 G G G A G G Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 18257c7e-ce2a-4dce-8bc0-db47ca8201a4 07284d3f-346f-473f-864e-5be1a95560ff 2 25310747 25310747 G A SNP DNMT3A NM_022552.3 human genbank 54_36p -1 reviewed missense c.2644 p.R882C 1.000 superfamily_S-adenosyl-L-methionine-dependent methyltransferases HMMPfam_PWWP,HMMSmart_SM00293,HMMPfam_DNA_methylase,superfamily_FYVE/PHD zinc finger,PatternScan_C5_MTASE_1,superfamily_S-adenosyl-L-methionine-dependent methyltransferases,superfamily_Tudor/PWWP/MBT - no_errors 152 0 0.00 42 17 28.33 NA NA NA IDH1 0 genome.wustl.edu 36 2 208821357 208821357 + Missense_Mutation SNP C C T rs121913500 TCGA-AB-2802-03B-01W-0728-08 TCGA-AB-2802-11B-01W-0728-08 C C C T C C Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 18257c7e-ce2a-4dce-8bc0-db47ca8201a4 07284d3f-346f-473f-864e-5be1a95560ff 2 208821357 208821357 C T SNP IDH1 NM_005896.2 human genbank 54_36p -1 reviewed missense c.395 p.R132H 1.000 HMMPfam_Iso_dh,superfamily_Isocitrate/Isopropylmalate dehydrogenase-like HMMPfam_Iso_dh,PatternScan_IDH_IMDH,superfamily_Isocitrate/Isopropylmalate dehydrogenase-like - no_errors 71 0 0.00 55 39 41.05 NA NA NA GRM7 0 genome.wustl.edu 36 3 7478316 7478316 + Silent SNP T T A TCGA-AB-2802-03B-01W-0728-08 TCGA-AB-2802-11B-01W-0728-08 T T T A T T Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 18257c7e-ce2a-4dce-8bc0-db47ca8201a4 07284d3f-346f-473f-864e-5be1a95560ff 3 7478316 7478316 T A SNP GRM7 NM_181874.2 human genbank 54_36p +1 reviewed silent c.1422 p.P474 0.995 HMMPfam_ANF_receptor,superfamily_SSF53822 HMMPfam_ANF_receptor,HMMPfam_NCD3G,HMMPfam_7tm_3,PatternScan_G_PROTEIN_RECEP_F3_1,PatternScan_G_PROTEIN_RECEP_F3_2,PatternScan_G_PROTEIN_RECEP_F3_3,superfamily_SSF53822 - no_errors 672 10 1.46 155 52 24.88 NA NA NA ANKRD30A 0 genome.wustl.edu 36 10 37495588 37495588 + Missense_Mutation SNP C C T TCGA-AB-2802-03B-01W-0728-08 TCGA-AB-2802-11B-01W-0728-08 C C C T C C Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 18257c7e-ce2a-4dce-8bc0-db47ca8201a4 07284d3f-346f-473f-864e-5be1a95560ff 10 37495588 37495588 C T SNP ANKRD30A NM_052997.2 human genbank 54_36p +1 validated missense c.1946 p.A649V 0.010 NULL PatternScan_ASP_PROTEASE,HMMPfam_Ank,HMMSmart_SM00248,superfamily_Ankyrin repeat - no_errors 69 0 0.00 25 19 42.22 NA NA NA KRT74 0 genome.wustl.edu 36 12 51250815 51250815 + Silent SNP G G A TCGA-AB-2802-03B-01W-0728-08 TCGA-AB-2802-11B-01W-0728-08 G G G A G G Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 18257c7e-ce2a-4dce-8bc0-db47ca8201a4 07284d3f-346f-473f-864e-5be1a95560ff 12 51250815 51250815 G A SNP KRT74 NM_175053.3 human genbank 54_36p -1 validated silent c.913 p.L305 0.958 HMMPfam_Filament HMMPfam_Filament,PatternScan_IF - no_errors 249 4 1.58 60 23 27.71 NA NA NA PTPN11 0 genome.wustl.edu 36 12 111372548 111372548 + Missense_Mutation SNP G G A TCGA-AB-2802-03B-01W-0728-08 TCGA-AB-2802-11B-01W-0728-08 G G G A G G Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 18257c7e-ce2a-4dce-8bc0-db47ca8201a4 07284d3f-346f-473f-864e-5be1a95560ff 12 111372548 111372548 G A SNP PTPN11 NM_002834.3 human genbank 54_36p +1 reviewed missense c.181 p.D61N 1.000 HMMPfam_SH2,HMMSmart_SM00252,superfamily_SH2 domain HMMPfam_Y_phosphatase,HMMSmart_SM00194,HMMPfam_SH2,HMMSmart_SM00252,HMMSmart_SM00404,PatternScan_TYR_PHOSPHATASE_1,superfamily_(Phosphotyrosine protein) phosphatases II,superfamily_SH2 domain - no_errors 423 0 0.00 51 23 31.08 NA NA NA EP400 0 genome.wustl.edu 36 12 131032838 131032838 + Silent SNP G G A TCGA-AB-2802-03B-01W-0728-08 TCGA-AB-2802-11B-01W-0728-08 G G G A G G Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 18257c7e-ce2a-4dce-8bc0-db47ca8201a4 07284d3f-346f-473f-864e-5be1a95560ff 12 131032838 131032838 G A SNP EP400 NM_015409.3 human genbank 54_36p +1 validated silent c.1788 p.Q596 0.985 NULL HMMPfam_SNF2_N,HMMPfam_Helicase_C,HMMSmart_HELICc,HMMPfam_HSA,superfamily_Homeodomain_like,HMMSmart_HSA,HMMSmart_DEXDc,superfamily_SSF52540 - no_errors 209 1 0.48 44 23 34.33 NA NA NA LOC728211 0 genome.wustl.edu 36 18 12066175 12066175 + RNA SNP A A G TCGA-AB-2802-03B-01W-0728-08 TCGA-AB-2802-11B-01W-0728-08 A A A G A A Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 18257c7e-ce2a-4dce-8bc0-db47ca8201a4 07284d3f-346f-473f-864e-5be1a95560ff 18 12066175 12066175 A G SNP LOC728211 XR_015403.2 human genbank 54_36p -1 model rna NULL NULL 0.973 - - - pseudogene 127 2 1.55 18 7 26.92 NA NA NA C20orf24 0 genome.wustl.edu 36 20 34673853 34673853 + Missense_Mutation SNP C C T TCGA-AB-2802-03B-01W-0728-08 TCGA-AB-2802-11B-01W-0728-08 C C C T C C Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 18257c7e-ce2a-4dce-8bc0-db47ca8201a4 07284d3f-346f-473f-864e-5be1a95560ff 20 34673853 34673853 C T SNP C20orf24 NM_199483.2 human genbank 54_36p +1 validated missense c.245 p.P82L 0.994 HMMPfam_Rab5ip HMMPfam_Rab5ip - no_errors 375 3 0.79 32 17 34.00 NA NA NA MT-ND5 0 genome.wustl.edu 36 MT 13059 13059 + Frame_Shift_Del DEL C C - TCGA-AB-2802-03B-01W-0728-08 TCGA-AB-2802-11B-01W-0728-08 C C C - C C Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 18257c7e-ce2a-4dce-8bc0-db47ca8201a4 07284d3f-346f-473f-864e-5be1a95560ff MT 13059 13059 C - DEL MT-ND5 ENST00000361567 human ensembl 54_36p +1 known frame_shift_del c.722 p.P242fs NULL HMMPfam_Oxidored_q1 HMMPfam_Oxidored_q1_N,HMMPfam_Oxidored_q1,HMMPfam_NADH5_C - no_errors 623 4 0.64 682 193 21.33 NA NA NA NPM1 0 genome.wustl.edu 36 5 170767341 170767342 + Frame_Shift_Ins INS - - GAGGAGG TCGA-AB-2802-03B-01W-0728-08 TCGA-AB-2802-11B-01W-0728-08 - - - GAGGAGG - - Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 18257c7e-ce2a-4dce-8bc0-db47ca8201a4 07284d3f-346f-473f-864e-5be1a95560ff 5 170767341 170767342 - GAGGAGG INS NPM1 NM_002520.1 human genbank 54_36p +1 validated frame_shift_ins c.804_805 p.I268fs 0.998:1.000 NULL HMMPfam_Nucleoplasmin,superfamily_Nucleoplasmin-like core domain - no_errors NA NA NA NA NA NA NA NA NA NPM1 0 genome.wustl.edu 36 5 170767342 170767343 + Frame_Shift_Ins INS - - T TCGA-AB-2802-03B-01W-0728-08 TCGA-AB-2802-11B-01W-0728-08 - - - T - - Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 18257c7e-ce2a-4dce-8bc0-db47ca8201a4 07284d3f-346f-473f-864e-5be1a95560ff 5 170767342 170767343 - T INS NPM1 NM_002520.1 human genbank 54_36p +1 validated frame_shift_ins c.805_806 p.N270fs 1.000:1.000 NULL HMMPfam_Nucleoplasmin,superfamily_Nucleoplasmin-like core domain - no_errors 163 0 0.00 49 0 0.00 NA NA NA