Hugo_Symbol Entrez_Gene_Id Center NCBI_Build Chromosome Start_Position End_Position Strand Variant_Classification Variant_Type Reference_Allele Tumor_Seq_Allele1 Tumor_Seq_Allele2 dbSNP_RS dbSNP_Val_Status Tumor_Sample_Barcode Matched_Norm_Sample_Barcode Match_Norm_Seq_Allele1 Match_Norm_Seq_Allele2 Tumor_Validation_Allele1 Tumor_Validation_Allele2 Match_Norm_Validation_Allele1 Match_Norm_Validation_Allele2 Verification_Status Validation_Status Mutation_Status Sequencing_Phase Sequence_Source Validation_Method Score BAM_File Sequencer Tumor_Sample_UUID Matched_Norm_Sample_UUID chromosome_name start stop reference variant type gene_name transcript_name transcript_species transcript_source transcript_version strand transcript_status trv_type c_position amino_acid_change ucsc_cons domain all_domains deletion_substructures transcript_error NormalRefReads_WU NormalVarReads_WU NormalVAF_WU TumorRefReads_WU TumorVarReads_WU TumorVAF_WU RNARefReads_WU RNAVarReads_WU RNAVAF_WU GALNT2 0 genome.wustl.edu 36 1 228481673 228481673 + Missense_Mutation SNP A A C TCGA-AB-2821-03B-01W-0728-08 TCGA-AB-2821-11B-01W-0728-08 A A A C A A Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 56d41ca3-78f9-4a0d-801c-1ecf4f1be249 e031e4fa-53fd-4e94-8459-7effb8460789 1 228481673 228481673 A C SNP GALNT2 NM_004481.3 human genbank 54_36p +1 reviewed missense c.1562 p.K521T 1.000 HMMPfam_Ricin_B_lectin,HMMSmart_SM00458,superfamily_Ricin B-like lectins HMMPfam_Ricin_B_lectin,HMMSmart_SM00458,HMMPfam_Glycos_transf_2,superfamily_Ricin B-like lectins,superfamily_Nucleotide-diphospho-sugar transferases - no_errors 36 2 5.26 91 61 39.87 48 35 42.17 MFSD6 0 genome.wustl.edu 36 2 191009228 191009228 + Missense_Mutation SNP T T G TCGA-AB-2821-03B-01W-0728-08 TCGA-AB-2821-11B-01W-0728-08 T T T G T T Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 56d41ca3-78f9-4a0d-801c-1ecf4f1be249 e031e4fa-53fd-4e94-8459-7effb8460789 2 191009228 191009228 T G SNP MFSD6 NM_017694.3 human genbank 54_36p +1 validated missense c.228 p.F76L 1.000 HMMPfam_MFS_1,superfamily_MFS_gen_substrate_transporter HMMPfam_MFS_1,superfamily_MFS_gen_substrate_transporter - no_errors 99 0 0.00 161 101 38.40 25 29 52.73 IDH1 0 genome.wustl.edu 36 2 208821358 208821358 + Missense_Mutation SNP G G A rs121913499 TCGA-AB-2821-03B-01W-0728-08 TCGA-AB-2821-11B-01W-0728-08 G G G A G G Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 56d41ca3-78f9-4a0d-801c-1ecf4f1be249 e031e4fa-53fd-4e94-8459-7effb8460789 2 208821358 208821358 G A SNP IDH1 NM_005896.2 human genbank 54_36p -1 reviewed missense c.394 p.R132C 1.000 HMMPfam_Iso_dh,superfamily_Isocitrate/Isopropylmalate dehydrogenase-like HMMPfam_Iso_dh,PatternScan_IDH_IMDH,superfamily_Isocitrate/Isopropylmalate dehydrogenase-like - no_errors 33 0 0.00 93 55 36.67 81 42 34.15 ATG16L1 0 genome.wustl.edu 36 2 233866685 233866685 + Missense_Mutation SNP T T A TCGA-AB-2821-03B-01W-0728-08 TCGA-AB-2821-11B-01W-0728-08 T T T A T T Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 56d41ca3-78f9-4a0d-801c-1ecf4f1be249 e031e4fa-53fd-4e94-8459-7effb8460789 2 233866685 233866685 T A SNP ATG16L1 NM_030803.3 human genbank 54_36p +1 validated missense c.1673 p.L558Q 0.994 HMMSmart_SM00320,superfamily_WD40 repeat-like,HMMPfam_WD40 HMMSmart_SM00320,superfamily_WD40 repeat-like,HMMPfam_ATG16,PatternScan_WD_REPEATS_1,HMMPfam_WD40 - no_errors 262 0 0.00 483 280 36.46 23 10 30.30 BOD1L 0 genome.wustl.edu 36 4 13224941 13224941 + Missense_Mutation SNP T T C TCGA-AB-2821-03B-01W-0728-08 TCGA-AB-2821-11B-01W-0728-08 T T T C T T Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 56d41ca3-78f9-4a0d-801c-1ecf4f1be249 e031e4fa-53fd-4e94-8459-7effb8460789 4 13224941 13224941 T C SNP BOD1L NM_148894.2 human genbank 54_36p -1 validated missense c.1151 p.K384R 0.002 superfamily_SSF81995 HMMPfam_AT_hook,HMMSmart_AT_hook,superfamily_SSF81995 - no_errors 74 0 0.00 154 90 36.59 30 37 55.22 FAT2 0 genome.wustl.edu 36 5 150909157 150909157 + Missense_Mutation SNP C C T TCGA-AB-2821-03B-01W-0728-08 TCGA-AB-2821-11B-01W-0728-08 C C C T C C Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 56d41ca3-78f9-4a0d-801c-1ecf4f1be249 e031e4fa-53fd-4e94-8459-7effb8460789 5 150909157 150909157 C T SNP FAT2 NM_001447.2 human genbank 54_36p -1 reviewed missense c.4681 p.E1561K 1.000 HMMPfam_Cadherin,superfamily_Cadherin-like HMMSmart_SM00282,HMMSmart_SM00179,HMMPfam_Cadherin,HMMSmart_SM00112,PatternScan_CADHERIN_1,HMMPfam_EGF,HMMSmart_SM00181,superfamily_Concanavalin A-like lectins/glucanases,HMMPfam_Laminin_G_2,PatternScan_EGF_1,PatternScan_EGF_2,superfamily_Cadherin-like,superfamily_EGF/Laminin - no_errors 27 0 0.00 91 73 44.51 NA NA NA SYNGAP1 0 genome.wustl.edu 36 6 33517365 33517365 + Silent SNP C C T TCGA-AB-2821-03B-01W-0728-08 TCGA-AB-2821-11B-01W-0728-08 C C C T C C Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 56d41ca3-78f9-4a0d-801c-1ecf4f1be249 e031e4fa-53fd-4e94-8459-7effb8460789 6 33517365 33517365 C T SNP SYNGAP1 NM_006772.2 human genbank 54_36p +1 validated silent c.2100 p.P700 0.996 HMMSmart_SM00323,superfamily_GTPase activation domain GAP HMMPfam_C2,HMMSmart_SM00239,HMMSmart_SM00233,HMMPfam_RasGAP,HMMSmart_SM00323,PatternScan_RAS_GTPASE_ACTIV_1,superfamily_GTPase activation domain GAP,superfamily_C2 domain (Calcium/lipid-binding domain CaLB),superfamily_PH domain-like - no_errors 257 1 0.39 201 121 37.12 19 26 57.78 RUNX1T1 0 genome.wustl.edu 36 8 93096001 93096001 + Silent SNP G G A TCGA-AB-2821-03B-01W-0728-08 TCGA-AB-2821-11B-01W-0728-08 G G G A G G Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 56d41ca3-78f9-4a0d-801c-1ecf4f1be249 e031e4fa-53fd-4e94-8459-7effb8460789 8 93096001 93096001 G A SNP RUNX1T1 NM_175634.2 human genbank 54_36p -1 reviewed silent c.450 p.T150 0.845 HMMPfam_TAFH,HMMSmart_SM00549 HMMPfam_zf-MYND,PatternScan_ZF_MYND_1,HMMPfam_TAFH,HMMSmart_SM00549,HMMPfam_NHR2 - no_errors 184 0 0.00 348 176 33.46 1 0 0.00 C10orf28 0 genome.wustl.edu 36 10 99958685 99958685 + Missense_Mutation SNP G G A TCGA-AB-2821-03B-01W-0728-08 TCGA-AB-2821-11B-01W-0728-08 G G G A G G Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 56d41ca3-78f9-4a0d-801c-1ecf4f1be249 e031e4fa-53fd-4e94-8459-7effb8460789 10 99958685 99958685 G A SNP C10orf28 NM_014472.4 human genbank 54_36p +1 validated missense c.824 p.G275D 0.015 NULL NULL - no_errors 110 0 0.00 158 76 32.20 15 9 37.50 OR8H2 0 genome.wustl.edu 36 11 55629610 55629610 + Silent SNP C C T TCGA-AB-2821-03B-01W-0728-08 TCGA-AB-2821-11B-01W-0728-08 C C C T C C Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 56d41ca3-78f9-4a0d-801c-1ecf4f1be249 e031e4fa-53fd-4e94-8459-7effb8460789 11 55629610 55629610 C T SNP OR8H2 NM_001005200.1 human genbank 54_36p +1 provisional silent c.516 p.N172 0.025 HMMPfam_7tm_1,superfamily_SSF81321 HMMPfam_7tm_1,PatternScan_G_PROTEIN_RECEP_F1_1,superfamily_SSF81321 - no_errors 39 0 0.00 184 103 35.89 NA NA NA NTRK3 0 genome.wustl.edu 36 15 86273475 86273475 + Missense_Mutation SNP A A G TCGA-AB-2821-03B-01W-0728-08 TCGA-AB-2821-11B-01W-0728-08 A A A G A A Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 56d41ca3-78f9-4a0d-801c-1ecf4f1be249 e031e4fa-53fd-4e94-8459-7effb8460789 15 86273475 86273475 A G SNP NTRK3 NM_001012338.1 human genbank 54_36p -1 reviewed missense c.2084 p.I695T 1.000 HMMPfam_Pkinase_Tyr,HMMSmart_SM00219,HMMSmart_SM00220,superfamily_Protein kinase-like (PK-like) HMMPfam_LRRNT,HMMSmart_SM00013,HMMSmart_SM00082,HMMPfam_Pkinase_Tyr,HMMSmart_SM00219,HMMPfam_LRR_1,PatternScan_RECEPTOR_TYR_KIN_II,HMMSmart_SM00220,HMMSmart_SM00409,PatternScan_PROTEIN_KINASE_TYR,superfamily_Protein kinase-like (PK-like),HMMPfam_I-set,HMMPfam_ig,PatternScan_PROTEIN_KINASE_ATP,superfamily_Immunoglobulin,superfamily_L domain-like - no_errors 128 0 0.00 163 92 35.38 NA NA NA IDH2 0 genome.wustl.edu 36 15 88432842 88432842 + Missense_Mutation SNP C C T rs121913503 TCGA-AB-2821-03B-01W-0728-08 TCGA-AB-2821-11B-01W-0728-08 C C C T C C Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 56d41ca3-78f9-4a0d-801c-1ecf4f1be249 e031e4fa-53fd-4e94-8459-7effb8460789 15 88432842 88432842 C T SNP IDH2 NM_002168.2 human genbank 54_36p -1 reviewed missense c.515 p.R172K 1.000 HMMPfam_Iso_dh,superfamily_Isocitrate/Isopropylmalate dehydrogenase-like HMMPfam_Iso_dh,PatternScan_IDH_IMDH,superfamily_Isocitrate/Isopropylmalate dehydrogenase-like - no_errors 40 0 0.00 144 18 11.11 169 21 11.05 ASXL1 0 genome.wustl.edu 36 20 30486373 30486373 + Nonsense_Mutation SNP C C T TCGA-AB-2821-03B-01W-0728-08 TCGA-AB-2821-11B-01W-0728-08 C C C T C C Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 56d41ca3-78f9-4a0d-801c-1ecf4f1be249 e031e4fa-53fd-4e94-8459-7effb8460789 20 30486373 30486373 C T SNP ASXL1 NM_015338.4 human genbank 54_36p +1 reviewed nonsense c.2197 p.Q733* 0.002 NULL NULL - no_errors 8 0 0.00 105 44 28.95 47 35 42.68 U2AF1 0 genome.wustl.edu 36 21 43387846 43387846 + Missense_Mutation SNP T T G TCGA-AB-2821-03B-01W-0728-08 TCGA-AB-2821-11B-01W-0728-08 T T T G T T Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 56d41ca3-78f9-4a0d-801c-1ecf4f1be249 e031e4fa-53fd-4e94-8459-7effb8460789 21 43387846 43387846 T G SNP U2AF1 NM_001025203.1 human genbank 54_36p -1 reviewed missense c.470 p.Q157P 1.000 HMMPfam_zf-CCCH,HMMSmart_ZnF_C3H1 HMMPfam_RRM_1,HMMSmart_RRM,HMMPfam_zf-CCCH,HMMSmart_ZnF_C3H1,superfamily_SSF54928 - no_errors 22 0 0.00 69 54 43.55 35 48 57.83 RUNX1 0 genome.wustl.edu 36 21 35174864 35174865 + Frame_Shift_Ins INS - - CC TCGA-AB-2821-03B-01W-0728-08 TCGA-AB-2821-11B-01W-0728-08 - - - CC - - Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 56d41ca3-78f9-4a0d-801c-1ecf4f1be249 e031e4fa-53fd-4e94-8459-7effb8460789 21 35174864 35174865 - CC INS RUNX1 NM_001754.2 human genbank 54_36p -1 reviewed frame_shift_ins c.368_367 p.D123fs 0.999:1.000 superfamily_p53-like transcription factors,HMMPfam_Runt superfamily_p53-like transcription factors,HMMPfam_Runt,HMMPfam_RunxI - no_errors 35 0 0.00 68 29 29.90 144 74 33.94