Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	NormalRefReads_WU	NormalVarReads_WU	NormalVAF_WU	TumorRefReads_WU	TumorVarReads_WU	TumorVAF_WU	RNARefReads_WU	RNAVarReads_WU	RNAVAF_WU
GJB4	0	genome.wustl.edu	36	1	34999735	34999735	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2832-03B-01W-0728-08	TCGA-AB-2832-11B-01W-0729-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	c6730725-42e7-4f23-a91d-d1c02c2812d0	d61a25b6-8cb0-4519-88fd-2995333f959c	1	34999735	34999735	G	A	SNP	GJB4	NM_153212.1	human	genbank	54_36p	+1	validated	missense	c.293	p.R98H	0.975	HMMPfam_Connexin	HMMPfam_Connexin,HMMSmart_SM00037,PatternScan_CONNEXINS_1,PatternScan_CONNEXINS_2,HMMPfam_Connexin_CCC	-	no_errors	49	2	3.92	69	51	42.15	NA	NA	NA
LOC389000	0	genome.wustl.edu	36	2	91440296	91440296	+	Missense_Mutation	SNP	A	A	G			TCGA-AB-2832-03B-01W-0728-08	TCGA-AB-2832-11B-01W-0729-08	A	A	A	G	A	A	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	c6730725-42e7-4f23-a91d-d1c02c2812d0	d61a25b6-8cb0-4519-88fd-2995333f959c	2	91440296	91440296	A	G	SNP	LOC389000	XM_371534.1	human	genbank	54_36p	-1	model	missense	c.1130	p.L377P	1.000	HMMPfam_Na_H_Exchanger	HMMPfam_Na_H_Exchanger	-	pseudogene	30	1	3.23	78	18	18.75	1	0	0.00
ZNF394	0	genome.wustl.edu	36	7	98929185	98929185	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2832-03B-01W-0728-08	TCGA-AB-2832-11B-01W-0729-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	c6730725-42e7-4f23-a91d-d1c02c2812d0	d61a25b6-8cb0-4519-88fd-2995333f959c	7	98929185	98929185	C	T	SNP	ZNF394	NM_032164.2	human	genbank	54_36p	-1	provisional	missense	c.1589	p.C530Y	1.000	HMMPfam_zf-C2H2,PatternScan_ZINC_FINGER_C2H2_1,HMMSmart_SM00355,superfamily_C2H2 and C2HC zinc fingers	HMMPfam_KRAB,HMMSmart_SM00349,superfamily_KRAB domain (Kruppel-associated box Pfam 01352),HMMPfam_SCAN,HMMSmart_SM00431,HMMPfam_zf-C2H2,PatternScan_ZINC_FINGER_C2H2_1,HMMSmart_SM00355,superfamily_C2H2 and C2HC zinc fingers	-	no_errors	281	20	6.64	153	94	37.90	86	94	52.22
ZC3HC1	0	genome.wustl.edu	36	7	129453268	129453268	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2832-03B-01W-0728-08	TCGA-AB-2832-11B-01W-0729-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	c6730725-42e7-4f23-a91d-d1c02c2812d0	d61a25b6-8cb0-4519-88fd-2995333f959c	7	129453268	129453268	C	T	SNP	ZC3HC1	NM_016478.3	human	genbank	54_36p	-1	validated	missense	c.742	p.A248T	1.000	NULL	HMMPfam_zf-C3HC	-	no_errors	62	4	6.06	47	38	43.68	13	15	53.57
PTAR1	0	genome.wustl.edu	36	9	71537035	71537035	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2832-03B-01W-0728-08	TCGA-AB-2832-11B-01W-0729-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	c6730725-42e7-4f23-a91d-d1c02c2812d0	d61a25b6-8cb0-4519-88fd-2995333f959c	9	71537035	71537035	G	A	SNP	PTAR1	NM_001099666.1	human	genbank	54_36p	-1	validated	missense	c.482	p.T161I	0.715	superfamily_Prenyl_trans	HMMPfam_PPTA,superfamily_Prenyl_trans	-	no_errors	97	7	6.73	97	88	47.31	7	8	53.33
PLEKHH1	0	genome.wustl.edu	36	14	67110289	67110289	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2832-03B-01W-0728-08	TCGA-AB-2832-11B-01W-0729-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	c6730725-42e7-4f23-a91d-d1c02c2812d0	d61a25b6-8cb0-4519-88fd-2995333f959c	14	67110289	67110289	C	T	SNP	PLEKHH1	NM_020715.2	human	genbank	54_36p	+1	validated	missense	c.1858	p.P620S	1.000	HMMPfam_PH,HMMSmart_SM00233,superfamily_PH domain-like	HMMPfam_MyTH4,HMMSmart_SM00139,HMMPfam_PH,HMMSmart_SM00233,HMMPfam_FERM_M,superfamily_Second domain of FERM,HMMSmart_SM00295,superfamily_PH domain-like	-	no_errors	100	8	7.41	114	69	37.10	NA	NA	NA
VASH1	0	genome.wustl.edu	36	14	76314113	76314113	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2832-03B-01W-0728-08	TCGA-AB-2832-11B-01W-0729-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	c6730725-42e7-4f23-a91d-d1c02c2812d0	d61a25b6-8cb0-4519-88fd-2995333f959c	14	76314113	76314113	C	T	SNP	VASH1	NM_014909.4	human	genbank	54_36p	+1	validated	missense	c.971	p.S324F	1.000	NULL	NULL	-	no_errors	38	2	5.00	34	38	52.05	9	11	55.00
ADPGK	0	genome.wustl.edu	36	15	70832206	70832206	+	Silent	SNP	A	A	G			TCGA-AB-2832-03B-01W-0728-08	TCGA-AB-2832-11B-01W-0729-08	A	A	A	G	A	A	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	c6730725-42e7-4f23-a91d-d1c02c2812d0	d61a25b6-8cb0-4519-88fd-2995333f959c	15	70832206	70832206	A	G	SNP	ADPGK	NM_031284.4	human	genbank	54_36p	-1	validated	silent	c.1020	p.S340	0.316	HMMPfam_ADP_PFK_GK,superfamily_SSF53613	HMMPfam_ADP_PFK_GK,superfamily_SSF53613	-	no_errors	64	3	4.48	83	60	41.67	114	125	52.30
LOC728138	0	genome.wustl.edu	36	16	14990830	14990830	+	Missense_Mutation	SNP	T	T	C			TCGA-AB-2832-03B-01W-0728-08	TCGA-AB-2832-11B-01W-0729-08	T	T	T	C	T	T	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	c6730725-42e7-4f23-a91d-d1c02c2812d0	d61a25b6-8cb0-4519-88fd-2995333f959c	16	14990830	14990830	T	C	SNP	LOC728138	XM_001128282.2	human	genbank	54_36p	-1	model	missense	c.689	p.K230R	0.200	HMMPfam_DUF2152	HMMPfam_DUF2152	-	no_errors	26	0	0.00	42	11	20.75	34	1	2.86
PKD1L2	0	genome.wustl.edu	36	16	79719117	79719117	+	Silent	SNP	C	C	A			TCGA-AB-2832-03B-01W-0728-08	TCGA-AB-2832-11B-01W-0729-08	C	C	C	A	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	c6730725-42e7-4f23-a91d-d1c02c2812d0	d61a25b6-8cb0-4519-88fd-2995333f959c	16	79719117	79719117	C	A	SNP	PKD1L2	ENST00000299598	human	ensembl	54_36p	-1	known	silent	c.6108	p.V2036	1.000	HMMPfam_PKD_channel	HMMPfam_GPS,HMMSmart_SM00303,PatternScan_CHANNEL_COLICIN,HMMPfam_PLAT,HMMSmart_SM00308,HMMPfam_Lectin_C,HMMSmart_SM00034,superfamily_Lipase/lipooxygenase domain (PLAT/LH2 domain),HMMPfam_PKD_channel,superfamily_C-type lectin-like	-	no_errors	226	13	5.44	169	138	44.52	NA	NA	NA
ZNF486	0	genome.wustl.edu	36	19	20169074	20169074	+	Missense_Mutation	SNP	A	A	G			TCGA-AB-2832-03B-01W-0728-08	TCGA-AB-2832-11B-01W-0729-08	A	A	A	G	A	A	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	c6730725-42e7-4f23-a91d-d1c02c2812d0	d61a25b6-8cb0-4519-88fd-2995333f959c	19	20169074	20169074	A	G	SNP	ZNF486	NM_052852.2	human	genbank	54_36p	+1	provisional	missense	c.555	p.I185M	0.281	superfamily_SSF57667	HMMPfam_KRAB,HMMSmart_KRAB,superfamily_Krueppel-associated_box,HMMPfam_zf-C2H2,PatternScan_ZINC_FINGER_C2H2_1,HMMSmart_ZnF_C2H2,superfamily_SSF57667	-	no_errors	57	0	0.00	68	59	46.46	NA	NA	NA
SREBF2	0	genome.wustl.edu	36	22	40603972	40603972	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2832-03B-01W-0728-08	TCGA-AB-2832-11B-01W-0729-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	c6730725-42e7-4f23-a91d-d1c02c2812d0	d61a25b6-8cb0-4519-88fd-2995333f959c	22	40603972	40603972	G	A	SNP	SREBF2	NM_004599.2	human	genbank	54_36p	+1	reviewed	missense	c.1660	p.V554M	1.000	NULL	HMMPfam_HLH,HMMSmart_HLH,superfamily_HLH_basic	-	no_errors	91	6	6.19	79	50	38.76	59	71	54.62