Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	NormalRefReads_WU	NormalVarReads_WU	NormalVAF_WU	TumorRefReads_WU	TumorVarReads_WU	TumorVAF_WU	RNARefReads_WU	RNAVarReads_WU	RNAVAF_WU
HSP90B3P	0	genome.wustl.edu	36	1	91880656	91880656	+	Silent	SNP	C	C	T			TCGA-AB-2853-03D-01W-0755-09	TCGA-AB-2853-11D-01W-0755-09	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	9e238bbc-61ba-4966-b30e-ba7ab1a5b11b	a8e7b351-f635-4026-b352-8129f8caa837	1	91880656	91880656	C	T	SNP	HSP90B3P	ENST00000370405	human	ensembl	54_36p	+1	known	silent	c.225	p.C75	0.671	NULL	superfamily_Ribosomal_S5_D2-typ_fold,HMMPfam_HSP90,superfamily_SSF110942	-	no_errors	185	7	3.65	170	118	40.83	NA	NA	NA
DNMT3A	0	genome.wustl.edu	36	2	25310746	25310746	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2853-03D-01W-0755-09	TCGA-AB-2853-11D-01W-0755-09	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	9e238bbc-61ba-4966-b30e-ba7ab1a5b11b	a8e7b351-f635-4026-b352-8129f8caa837	2	25310746	25310746	C	T	SNP	DNMT3A	NM_022552.3	human	genbank	54_36p	-1	reviewed	missense	c.2645	p.R882H	1.000	superfamily_S-adenosyl-L-methionine-dependent methyltransferases	HMMPfam_PWWP,HMMSmart_SM00293,HMMPfam_DNA_methylase,superfamily_FYVE/PHD zinc finger,PatternScan_C5_MTASE_1,superfamily_S-adenosyl-L-methionine-dependent methyltransferases,superfamily_Tudor/PWWP/MBT	-	no_errors	98	7	6.67	62	44	41.12	34	39	53.42
KLHL5	0	genome.wustl.edu	36	4	38791161	38791161	+	Silent	SNP	G	G	A			TCGA-AB-2853-03D-01W-0755-09	TCGA-AB-2853-11D-01W-0755-09	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	9e238bbc-61ba-4966-b30e-ba7ab1a5b11b	a8e7b351-f635-4026-b352-8129f8caa837	4	38791161	38791161	G	A	SNP	KLHL5	NM_015990.1	human	genbank	54_36p	+1	validated	silent	c.1953	p.T651	0.771	HMMPfam_Kelch_1,HMMSmart_SM00612,superfamily_Galactose oxidase central domain	HMMSmart_SM00225,HMMPfam_Kelch_1,HMMSmart_SM00612,superfamily_Galactose oxidase central domain,superfamily_POZ domain,HMMPfam_BACK,HMMPfam_BTB	-	no_errors	66	5	7.04	51	24	32.00	17	14	45.16
ANK2	0	genome.wustl.edu	36	4	114473772	114473772	+	Missense_Mutation	SNP	C	C	A			TCGA-AB-2853-03D-01W-0755-09	TCGA-AB-2853-11D-01W-0755-09	C	C	C	A	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	9e238bbc-61ba-4966-b30e-ba7ab1a5b11b	a8e7b351-f635-4026-b352-8129f8caa837	4	114473772	114473772	C	A	SNP	ANK2	NM_001148.1	human	genbank	54_36p	+1	reviewed	missense	c.3338	p.T1113N	0.998	NULL	HMMPfam_Death,HMMSmart_DEATH,HMMPfam_ZU5,HMMPfam_Ank,HMMSmart_ANK,superfamily_ANK,superfamily_DEATH_like,PatternScan_ALDEHYDE_DEHYDR_GLU	-	no_errors	133	10	6.99	116	90	43.48	NA	NA	NA
SLCO6A1	0	genome.wustl.edu	36	5	101862376	101862376	+	Silent	SNP	G	G	A			TCGA-AB-2853-03D-01W-0755-09	TCGA-AB-2853-11D-01W-0755-09	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	9e238bbc-61ba-4966-b30e-ba7ab1a5b11b	a8e7b351-f635-4026-b352-8129f8caa837	5	101862376	101862376	G	A	SNP	SLCO6A1	NM_173488.3	human	genbank	54_36p	-1	validated	silent	c.72	p.A24	0.000	NULL	HMMPfam_OATP,HMMPfam_Kazal_2,superfamily_MFS general substrate transporter,superfamily_Kazal-type serine protease inhibitors	-	no_errors	62	3	4.62	42	33	42.31	NA	NA	NA
SLC13A1	0	genome.wustl.edu	36	7	122542939	122542939	+	Missense_Mutation	SNP	C	C	A			TCGA-AB-2853-03D-01W-0755-09	TCGA-AB-2853-11D-01W-0755-09	C	C	C	A	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	9e238bbc-61ba-4966-b30e-ba7ab1a5b11b	a8e7b351-f635-4026-b352-8129f8caa837	7	122542939	122542939	C	A	SNP	SLC13A1	NM_022444.3	human	genbank	54_36p	-1	validated	missense	c.1657	p.A553S	1.000	HMMPfam_Na_sulph_symp	HMMPfam_Na_sulph_symp,PatternScan_NA_SULFATE	-	no_errors	120	10	7.69	107	91	45.96	NA	NA	NA
AKR1CL1	0	genome.wustl.edu	36	10	5193906	5193906	+	Silent	SNP	C	C	T			TCGA-AB-2853-03D-01W-0755-09	TCGA-AB-2853-11D-01W-0755-09	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	9e238bbc-61ba-4966-b30e-ba7ab1a5b11b	a8e7b351-f635-4026-b352-8129f8caa837	10	5193906	5193906	C	T	SNP	AKR1CL1	NM_001007536.3	human	genbank	54_36p	-1	provisional	silent	c.291	p.L97	0.819	HMMPfam_Aldo_ket_red,superfamily_Aldo/ket_red	HMMPfam_Aldo_ket_red,superfamily_Aldo/ket_red,PatternScan_ALDOKETO_REDUCTASE_1	-	no_errors	105	8	7.08	113	113	49.56	0	0	0.00
SMC3	0	genome.wustl.edu	36	10	112346164	112346164	+	Missense_Mutation	SNP	G	G	C			TCGA-AB-2853-03D-01W-0755-09	TCGA-AB-2853-11D-01W-0755-09	G	G	G	C	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	9e238bbc-61ba-4966-b30e-ba7ab1a5b11b	a8e7b351-f635-4026-b352-8129f8caa837	10	112346164	112346164	G	C	SNP	SMC3	NM_005445.3	human	genbank	54_36p	+1	reviewed	missense	c.1982	p.R661P	1.000	HMMPfam_SMC_N,superfamily_Smc hinge domain,superfamily_P-loop containing nucleoside triphosphate hydrolases	HMMPfam_SMC_N,HMMPfam_SMC_hinge,superfamily_Smc hinge domain,PatternScan_ABC_TRANSPORTER_1,superfamily_P-loop containing nucleoside triphosphate hydrolases,superfamily_BAG domain	-	no_errors	56	4	6.67	38	50	56.18	78	68	46.58
LOC440181	0	genome.wustl.edu	36	14	58364276	58364276	+	RNA	SNP	C	C	T			TCGA-AB-2853-03D-01W-0755-09	TCGA-AB-2853-11D-01W-0755-09	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	9e238bbc-61ba-4966-b30e-ba7ab1a5b11b	a8e7b351-f635-4026-b352-8129f8caa837	14	58364276	58364276	C	T	SNP	LOC440181	XR_017581.1	human	genbank	54_36p	-1	model	rna	NULL	NULL	1.000	-	-	-	pseudogene	128	15	10.49	116	94	44.55	NA	NA	NA
SPTLC2	0	genome.wustl.edu	36	14	77088240	77088240	+	Missense_Mutation	SNP	T	T	C			TCGA-AB-2853-03D-01W-0755-09	TCGA-AB-2853-11D-01W-0755-09	T	T	T	C	T	T	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	9e238bbc-61ba-4966-b30e-ba7ab1a5b11b	a8e7b351-f635-4026-b352-8129f8caa837	14	77088240	77088240	T	C	SNP	SPTLC2	NM_004863.2	human	genbank	54_36p	-1	validated	missense	c.1255	p.I419V	1.000	HMMPfam_Aminotran_1_2,superfamily_PyrdxlP-dep_Trfase_major	PatternScan_AA_TRANSFER_CLASS_2,HMMPfam_Aminotran_1_2,superfamily_PyrdxlP-dep_Trfase_major	-	no_errors	120	9	6.98	121	101	44.89	38	146	78.92
TANC2	0	genome.wustl.edu	36	17	58851938	58851938	+	Silent	SNP	C	C	T			TCGA-AB-2853-03D-01W-0755-09	TCGA-AB-2853-11D-01W-0755-09	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	9e238bbc-61ba-4966-b30e-ba7ab1a5b11b	a8e7b351-f635-4026-b352-8129f8caa837	17	58851938	58851938	C	T	SNP	TANC2	NM_025185.3	human	genbank	54_36p	+1	validated	silent	c.4863	p.A1621	0.891	NULL	HMMPfam_TPR_1,HMMPfam_Ank,HMMSmart_SM00248,superfamily_Ankyrin repeat,HMMSmart_SM00028,superfamily_TPR-like,superfamily_P-loop containing nucleoside triphosphate hydrolases	-	no_errors	219	5	2.23	76	91	53.53	6	4	40.00
NPM1	0	genome.wustl.edu	36	5	170770148	170770149	+	Frame_Shift_Ins	INS	-	-	TCTG			TCGA-AB-2853-03D-01W-0755-09	TCGA-AB-2853-11D-01W-0755-09	-	-	-	TCTG	-	-	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	9e238bbc-61ba-4966-b30e-ba7ab1a5b11b	a8e7b351-f635-4026-b352-8129f8caa837	5	170770148	170770149	-	TCTG	INS	NPM1	NM_002520.1	human	genbank	54_36p	+1	validated	frame_shift_ins	c.859_860	p.W288fs	1.000:1.000	NULL	HMMPfam_Nucleoplasmin,superfamily_Nucleoplasmin-like core domain	-	no_errors	NA	NA	NA	NA	NA	NA	NA	NA	NA
FLT3	0	genome.wustl.edu	36	13	27506268	27506269	+	In_Frame_Ins	INS	-	-	TCTCTGAAATCAACGTAG			TCGA-AB-2853-03D-01W-0755-09	TCGA-AB-2853-11D-01W-0755-09	-	-	-	TCTCTGAAATCAACGTAG	-	-	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	9e238bbc-61ba-4966-b30e-ba7ab1a5b11b	a8e7b351-f635-4026-b352-8129f8caa837	13	27506268	27506269	-	TCTCTGAAATCAACGTAG	INS	FLT3	NM_004119.2	human	genbank	54_36p	-1	reviewed	in_frame_ins	c.1788_1787	p.596in_frame_insDYVDFR	0.794:0.991	superfamily_Kinase_like	HMMPfam_Pkinase_Tyr,HMMSmart_TyrKc,PatternScan_RECEPTOR_TYR_KIN_III,PatternScan_PROTEIN_KINASE_TYR,superfamily_Kinase_like,HMMPfam_ig,PatternScan_PROTEIN_KINASE_ATP,superfamily_SSF48726	-	no_errors	NA	NA	NA	NA	NA	NA	NA	NA	NA