Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	NormalRefReads_WU	NormalVarReads_WU	NormalVAF_WU	TumorRefReads_WU	TumorVarReads_WU	TumorVAF_WU	RNARefReads_WU	RNAVarReads_WU	RNAVAF_WU
ATP2B3	0	genome.wustl.edu	36	X	152478458	152478458	+	Silent	SNP	G	G	A			TCGA-AB-2865-03B-01W-0728-08	TCGA-AB-2865-11B-01W-0729-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	2f23cee2-d71d-474c-aa2c-0c1df979301c	fa23ecef-8a16-4fdb-8033-c547d06013bc	X	152478458	152478458	G	A	SNP	ATP2B3	NM_001001344.1	human	genbank	54_36p	+1	reviewed	silent	c.2703	p.T901	0.019	HMMPfam_Cation_ATPase_C,superfamily_Calcium ATPase transmembrane domain M	HMMPfam_Cation_ATPase_N,HMMPfam_Hydrolase,HMMPfam_Cation_ATPase_C,HMMPfam_E1-E2_ATPase,PatternScan_ATPASE_E1_E2,superfamily_HAD-like,superfamily_Calcium ATPase transduction domain A,superfamily_Metal cation-transporting ATPase ATP-binding domain N,superfamily_Calcium ATPase transmembrane domain M	-	no_errors	24	0	0.00	9	29	76.32	NA	NA	NA
PRAMEF2	0	genome.wustl.edu	36	1	12842416	12842416	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2865-03B-01W-0728-08	TCGA-AB-2865-11B-01W-0729-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	2f23cee2-d71d-474c-aa2c-0c1df979301c	fa23ecef-8a16-4fdb-8033-c547d06013bc	1	12842416	12842416	C	T	SNP	PRAMEF2	NM_023014.1	human	genbank	54_36p	+1	provisional	missense	c.569	p.T190M	0.002	superfamily_SSF52047	superfamily_SSF52047	-	no_errors	53	1	1.85	67	56	45.53	NA	NA	NA
MYOM3	0	genome.wustl.edu	36	1	24256576	24256576	+	Silent	SNP	G	G	A			TCGA-AB-2865-03B-01W-0728-08	TCGA-AB-2865-11B-01W-0729-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	2f23cee2-d71d-474c-aa2c-0c1df979301c	fa23ecef-8a16-4fdb-8033-c547d06013bc	1	24256576	24256576	G	A	SNP	MYOM3	NM_152372.3	human	genbank	54_36p	-1	validated	silent	c.4179	p.T1393	1.000	HMMSmart_SM00408,HMMSmart_SM00409,HMMPfam_I-set,superfamily_Immunoglobulin	HMMSmart_SM00408,HMMSmart_SM00409,HMMPfam_fn3,HMMSmart_SM00060,superfamily_Fibronectin type III,HMMPfam_I-set,HMMPfam_ig,PatternScan_EF_HAND_1,superfamily_Immunoglobulin	-	no_errors	113	5	4.24	87	65	42.21	NA	NA	NA
SLC27A3	0	genome.wustl.edu	36	1	152018355	152018355	+	Nonsense_Mutation	SNP	C	C	T			TCGA-AB-2865-03B-01W-0728-08	TCGA-AB-2865-11B-01W-0729-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	2f23cee2-d71d-474c-aa2c-0c1df979301c	fa23ecef-8a16-4fdb-8033-c547d06013bc	1	152018355	152018355	C	T	SNP	SLC27A3	ENST00000368659	human	ensembl	54_36p	+1	known	nonsense	c.34	p.R12*	0.000	NULL	superfamily_SSF56801	-	no_errors	149	8	5.10	82	42	33.87	3	1	25.00
MYOC	0	genome.wustl.edu	36	1	169872108	169872108	+	Nonsense_Mutation	SNP	G	G	T			TCGA-AB-2865-03B-01W-0728-08	TCGA-AB-2865-11B-01W-0729-08	G	G	G	T	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	2f23cee2-d71d-474c-aa2c-0c1df979301c	fa23ecef-8a16-4fdb-8033-c547d06013bc	1	169872108	169872108	G	T	SNP	MYOC	NM_000261.1	human	genbank	54_36p	-1	reviewed	nonsense	c.1095	p.Y365*	1.000	HMMPfam_OLF,HMMSmart_SM00284	HMMPfam_OLF,HMMSmart_SM00284	-	no_errors	111	2	1.77	128	95	42.41	NA	NA	NA
CLDN18	0	genome.wustl.edu	36	3	139225231	139225231	+	Missense_Mutation	SNP	G	G	T			TCGA-AB-2865-03B-01W-0728-08	TCGA-AB-2865-11B-01W-0729-08	G	G	G	T	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	2f23cee2-d71d-474c-aa2c-0c1df979301c	fa23ecef-8a16-4fdb-8033-c547d06013bc	3	139225231	139225231	G	T	SNP	CLDN18	NM_001002026.2	human	genbank	54_36p	+1	validated	missense	c.262	p.V88F	0.995	HMMPfam_PMP22_Claudin	HMMPfam_PMP22_Claudin,PatternScan_CLAUDIN	-	no_errors	292	1	0.34	87	89	50.00	NA	NA	NA
TET2	0	genome.wustl.edu	36	4	106377387	106377387	+	Nonsense_Mutation	SNP	C	C	T			TCGA-AB-2865-03B-01W-0728-08	TCGA-AB-2865-11B-01W-0729-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	2f23cee2-d71d-474c-aa2c-0c1df979301c	fa23ecef-8a16-4fdb-8033-c547d06013bc	4	106377387	106377387	C	T	SNP	TET2	NM_017628.1	human	genbank	54_36p	+1	validated	nonsense	c.2839	p.Q947*	1.000	NULL	NULL	-	no_errors	89	7	7.29	70	46	38.98	22	18	45.00
TTBK1	0	genome.wustl.edu	36	6	43338696	43338696	+	Missense_Mutation	SNP	A	A	G			TCGA-AB-2865-03B-01W-0728-08	TCGA-AB-2865-11B-01W-0729-08	A	A	A	G	A	A	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	2f23cee2-d71d-474c-aa2c-0c1df979301c	fa23ecef-8a16-4fdb-8033-c547d06013bc	6	43338696	43338696	A	G	SNP	TTBK1	NM_032538.1	human	genbank	54_36p	+1	validated	missense	c.1616	p.D539G	1.000	NULL	HMMSmart_SM00219,HMMSmart_SM00220,superfamily_Protein kinase-like (PK-like),PatternScan_PROTEIN_KINASE_ATP,HMMPfam_Pkinase	-	no_errors	38	3	7.32	32	16	33.33	NA	NA	NA
SLC26A3	0	genome.wustl.edu	36	7	107218912	107218912	+	Silent	SNP	C	C	T			TCGA-AB-2865-03B-01W-0728-08	TCGA-AB-2865-11B-01W-0729-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	2f23cee2-d71d-474c-aa2c-0c1df979301c	fa23ecef-8a16-4fdb-8033-c547d06013bc	7	107218912	107218912	C	T	SNP	SLC26A3	NM_000111.2	human	genbank	54_36p	-1	reviewed	silent	c.387	p.P129	0.919	NULL	HMMPfam_STAS,superfamily_STAS,HMMPfam_Sulfate_transp,PatternScan_SLC26A	-	no_errors	59	4	6.35	86	65	42.21	NA	NA	NA
PLXNA4	0	genome.wustl.edu	36	7	131516835	131516835	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2865-03B-01W-0728-08	TCGA-AB-2865-11B-01W-0729-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	2f23cee2-d71d-474c-aa2c-0c1df979301c	fa23ecef-8a16-4fdb-8033-c547d06013bc	7	131516835	131516835	C	T	SNP	PLXNA4	NM_020911.1	human	genbank	54_36p	-1	validated	missense	c.3337	p.E1113K	0.997	HMMPfam_TIG,HMMSmart_SM00429,superfamily_E set domains	HMMPfam_Sema,HMMSmart_SM00630,superfamily_Sema domain,HMMPfam_PSI,HMMPfam_TIG,HMMSmart_SM00429,HMMSmart_SM00423,superfamily_GTPase activation domain GAP,HMMPfam_Plexin_cytopl,superfamily_E set domains,superfamily_Plexin repeat	-	no_errors	138	2	1.43	73	64	46.72	NA	NA	NA
EZH2	0	genome.wustl.edu	36	7	148137095	148137095	+	Splice_Site	SNP	C	C	T			TCGA-AB-2865-03B-01W-0728-08	TCGA-AB-2865-11B-01W-0729-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	2f23cee2-d71d-474c-aa2c-0c1df979301c	fa23ecef-8a16-4fdb-8033-c547d06013bc	7	148137095	148137095	C	T	SNP	EZH2	NM_004456.3	human	genbank	54_36p	-1	reviewed	splice_site	c.2195+1	e18+1	1.000	-	-	-	no_errors	61	0	0.00	124	100	44.44	3	10	76.92
PKHD1L1	0	genome.wustl.edu	36	8	110481706	110481706	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2865-03B-01W-0728-08	TCGA-AB-2865-11B-01W-0729-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	2f23cee2-d71d-474c-aa2c-0c1df979301c	fa23ecef-8a16-4fdb-8033-c547d06013bc	8	110481706	110481706	G	A	SNP	PKHD1L1	NM_177531.4	human	genbank	54_36p	+1	validated	missense	c.1238	p.R413H	0.999	HMMSmart_SM00710,HMMSmart_SM00758,superfamily_Anthrax protective antigen	HMMPfam_TIG,HMMSmart_SM00429,HMMSmart_SM00710,superfamily_Cupredoxins,superfamily_Pectin lyase-like,HMMSmart_SM00758,superfamily_E set domains,HMMPfam_G8,superfamily_Anthrax protective antigen	-	no_errors	77	1	1.28	70	41	36.28	NA	NA	NA
JAK2	0	genome.wustl.edu	36	9	5063770	5063770	+	Missense_Mutation	SNP	G	G	T	rs77375493		TCGA-AB-2865-03B-01W-0728-08	TCGA-AB-2865-11B-01W-0729-08	G	G	G	T	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	2f23cee2-d71d-474c-aa2c-0c1df979301c	fa23ecef-8a16-4fdb-8033-c547d06013bc	9	5063770	5063770	G	T	SNP	JAK2	NM_004972.3	human	genbank	54_36p	+1	reviewed	missense	c.1849	p.V617F	1.000	HMMPfam_Pkinase_Tyr,HMMSmart_TyrKc,superfamily_Kinase_like	HMMPfam_SH2,HMMSmart_SH2,HMMPfam_Pkinase_Tyr,HMMSmart_TyrKc,PatternScan_PROTEIN_KINASE_TYR,superfamily_Kinase_like,PatternScan_PROTEIN_KINASE_ATP,PatternScan_FERM_1,PatternScan_FERM_2,HMMSmart_B41,superfamily_SSF55550	-	no_errors	79	1	1.25	68	40	37.04	14	20	58.82
KRAS	0	genome.wustl.edu	36	12	25289551	25289551	+	Missense_Mutation	SNP	C	C	T	rs121913529		TCGA-AB-2865-03B-01W-0728-08	TCGA-AB-2865-11B-01W-0729-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	2f23cee2-d71d-474c-aa2c-0c1df979301c	fa23ecef-8a16-4fdb-8033-c547d06013bc	12	25289551	25289551	C	T	SNP	KRAS	NM_033360.3	human	genbank	54_36p	-1	reviewed	missense	c.35	p.G12D	1.000	HMMSmart_SM00176,HMMSmart_SM00173,HMMSmart_SM00174,HMMSmart_SM00175,HMMPfam_Ras,superfamily_P-loop containing nucleoside triphosphate hydrolases	HMMSmart_SM00176,HMMSmart_SM00173,HMMSmart_SM00174,HMMSmart_SM00175,HMMPfam_Ras,superfamily_P-loop containing nucleoside triphosphate hydrolases	-	no_errors	11	0	0.00	80	14	14.89	23	8	25.81
DIS3	0	genome.wustl.edu	36	13	72243998	72243998	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2865-03B-01W-0728-08	TCGA-AB-2865-11B-01W-0729-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	2f23cee2-d71d-474c-aa2c-0c1df979301c	fa23ecef-8a16-4fdb-8033-c547d06013bc	13	72243998	72243998	C	T	SNP	DIS3	NM_014953.1	human	genbank	54_36p	-1	validated	missense	c.1541	p.R514K	0.986	HMMPfam_RNB	HMMPfam_RNB,PatternScan_RIBONUCLEASE_II,HMMSmart_SM00670,superfamily_PIN domain-like	-	no_errors	40	5	11.11	94	66	40.49	19	14	41.18
MYH4	0	genome.wustl.edu	36	17	10296271	10296271	+	Silent	SNP	G	G	A			TCGA-AB-2865-03B-01W-0728-08	TCGA-AB-2865-11B-01W-0729-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	2f23cee2-d71d-474c-aa2c-0c1df979301c	fa23ecef-8a16-4fdb-8033-c547d06013bc	17	10296271	10296271	G	A	SNP	MYH4	NM_017533.2	human	genbank	54_36p	-1	validated	silent	c.3450	p.I1150	1.000	HMMPfam_Myosin_tail_1	HMMSmart_IQ,HMMPfam_Myosin_head,HMMSmart_MYSc,HMMPfam_Myosin_tail_1,HMMPfam_Myosin_N,superfamily_SSF52540	-	no_errors	61	4	6.15	60	30	32.61	NA	NA	NA
PSG9	0	genome.wustl.edu	36	19	48463864	48463864	+	Silent	SNP	C	C	T			TCGA-AB-2865-03B-01W-0728-08	TCGA-AB-2865-11B-01W-0729-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	2f23cee2-d71d-474c-aa2c-0c1df979301c	fa23ecef-8a16-4fdb-8033-c547d06013bc	19	48463864	48463864	C	T	SNP	PSG9	NM_002784.3	human	genbank	54_36p	-1	validated	silent	c.342	p.R114	0.015	HMMSmart_SM00409,HMMPfam_V-set,superfamily_Immunoglobulin	HMMSmart_SM00408,HMMSmart_SM00409,HMMPfam_V-set,HMMPfam_ig,superfamily_Immunoglobulin	-	no_errors	276	3	1.08	122	114	48.31	NA	NA	NA
RUNX1	0	genome.wustl.edu	36	21	35153662	35153662	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2865-03B-01W-0728-08	TCGA-AB-2865-11B-01W-0729-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	2f23cee2-d71d-474c-aa2c-0c1df979301c	fa23ecef-8a16-4fdb-8033-c547d06013bc	21	35153662	35153662	C	T	SNP	RUNX1	NM_001754.2	human	genbank	54_36p	-1	reviewed	missense	c.592	p.D198N	1.000	superfamily_p53-like transcription factors,HMMPfam_Runt	superfamily_p53-like transcription factors,HMMPfam_Runt,HMMPfam_RunxI	-	no_errors	98	1	1.01	61	97	60.62	359	705	66.20
RUNX1	0	genome.wustl.edu	36	21	35174810	35174810	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2865-03B-01W-0728-08	TCGA-AB-2865-11B-01W-0729-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	2f23cee2-d71d-474c-aa2c-0c1df979301c	fa23ecef-8a16-4fdb-8033-c547d06013bc	21	35174810	35174810	G	A	SNP	RUNX1	NM_001754.2	human	genbank	54_36p	-1	reviewed	missense	c.422	p.S141L	1.000	superfamily_p53-like transcription factors,HMMPfam_Runt	superfamily_p53-like transcription factors,HMMPfam_Runt,HMMPfam_RunxI	-	no_errors	34	1	2.86	62	22	25.88	712	326	31.41
CACNG2	0	genome.wustl.edu	36	22	35428399	35428399	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2865-03B-01W-0728-08	TCGA-AB-2865-11B-01W-0729-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	2f23cee2-d71d-474c-aa2c-0c1df979301c	fa23ecef-8a16-4fdb-8033-c547d06013bc	22	35428399	35428399	C	T	SNP	CACNG2	NM_006078.2	human	genbank	54_36p	-1	reviewed	missense	c.169	p.V57I	1.000	HMMPfam_PMP22_Claudin	HMMPfam_PMP22_Claudin	-	no_errors	316	4	1.25	48	36	42.86	NA	NA	NA
TET2	0	genome.wustl.edu	36	4	106413250	106413251	+	Frame_Shift_Ins	INS	-	-	AT			TCGA-AB-2865-03B-01W-0728-08	TCGA-AB-2865-11B-01W-0729-08	-	-	-	AT	-	-	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	2f23cee2-d71d-474c-aa2c-0c1df979301c	fa23ecef-8a16-4fdb-8033-c547d06013bc	4	106413250	106413251	-	AT	INS	TET2	ENST00000265149	human	ensembl	54_36p	+1	known	frame_shift_ins	c.669_670	p.K223fs	1.000:1.000	NULL	NULL	-	no_start_codon	47	0	0.00	129	62	32.46	27	9	25.00
TET2	0	genome.wustl.edu	36	4	106413251	106413252	+	Frame_Shift_Ins	INS	-	-	TA			TCGA-AB-2865-03B-01W-0728-08	TCGA-AB-2865-11B-01W-0729-08	-	-	-	TA	-	-	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	2f23cee2-d71d-474c-aa2c-0c1df979301c	fa23ecef-8a16-4fdb-8033-c547d06013bc	4	106413251	106413252	-	TA	INS	TET2	ENST00000265149	human	ensembl	54_36p	+1	known	frame_shift_ins	c.670_671	p.K224fs	1.000:1.000	NULL	NULL	-	no_start_codon	48	0	0.00	191	0	0.00	37	0	0.00