Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	NormalRefReads_WU	NormalVarReads_WU	NormalVAF_WU	TumorRefReads_WU	TumorVarReads_WU	TumorVAF_WU	RNARefReads_WU	RNAVarReads_WU	RNAVAF_WU
KDM6A	0	genome.wustl.edu	36	X	44807944	44807944	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2867-03B-01W-0728-08	TCGA-AB-2867-11B-01W-0729-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	b3f3ba24-dfbe-4b4b-8502-83ec6ecd7df3	4e18dd6e-74b8-41c3-9665-900c92d39bee	X	44807944	44807944	C	T	SNP	UTX	NM_021140.2	human	genbank	54_36p	+1	validated	missense	c.1861	p.R621C	1.000	NULL	HMMPfam_TPR_1,HMMSmart_JmjC,HMMPfam_JmjC,HMMSmart_TPR,superfamily_SSF48452	-	no_errors	116	7	5.65	73	39	34.82	26	9	25.71
SPATA21	0	genome.wustl.edu	36	1	16608932	16608932	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2867-03B-01W-0728-08	TCGA-AB-2867-11B-01W-0729-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	b3f3ba24-dfbe-4b4b-8502-83ec6ecd7df3	4e18dd6e-74b8-41c3-9665-900c92d39bee	1	16608932	16608932	G	A	SNP	SPATA21	NM_198546.1	human	genbank	54_36p	-1	provisional	missense	c.338	p.S113L	0.005	NULL	PatternScan_EF_HAND_1,HMMPfam_efhand,superfamily_SSF47473	-	no_errors	390	9	2.24	183	80	30.42	NA	NA	NA
OR2M3	0	genome.wustl.edu	36	1	246433759	246433759	+	Nonsense_Mutation	SNP	T	T	A			TCGA-AB-2867-03B-01W-0728-08	TCGA-AB-2867-11B-01W-0729-08	T	T	T	A	T	T	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	b3f3ba24-dfbe-4b4b-8502-83ec6ecd7df3	4e18dd6e-74b8-41c3-9665-900c92d39bee	1	246433759	246433759	T	A	SNP	OR2M3	NM_001004689.1	human	genbank	54_36p	+1	provisional	nonsense	c.767	p.L256*	0.000	HMMPfam_7tm_1,superfamily_Family A G protein-coupled receptor-like	HMMPfam_7tm_1,PatternScan_G_PROTEIN_RECEP_F1_1,superfamily_Family A G protein-coupled receptor-like	-	no_errors	136	3	2.13	143	70	32.86	NA	NA	NA
DNMT3A	0	genome.wustl.edu	36	2	25312191	25312191	+	Missense_Mutation	SNP	T	T	C			TCGA-AB-2867-03B-01W-0728-08	TCGA-AB-2867-11B-01W-0729-08	T	T	T	C	T	T	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	b3f3ba24-dfbe-4b4b-8502-83ec6ecd7df3	4e18dd6e-74b8-41c3-9665-900c92d39bee	2	25312191	25312191	T	C	SNP	DNMT3A	NM_022552.3	human	genbank	54_36p	-1	reviewed	missense	c.2486	p.K829R	1.000	superfamily_S-adenosyl-L-methionine-dependent methyltransferases	HMMPfam_PWWP,HMMSmart_SM00293,HMMPfam_DNA_methylase,superfamily_FYVE/PHD zinc finger,PatternScan_C5_MTASE_1,superfamily_S-adenosyl-L-methionine-dependent methyltransferases,superfamily_Tudor/PWWP/MBT	-	no_errors	208	10	4.55	45	29	38.67	9	21	70.00
DNMT3A	0	genome.wustl.edu	36	2	25322559	25322559	+	Missense_Mutation	SNP	T	T	C			TCGA-AB-2867-03B-01W-0728-08	TCGA-AB-2867-11B-01W-0729-08	T	T	T	C	T	T	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	b3f3ba24-dfbe-4b4b-8502-83ec6ecd7df3	4e18dd6e-74b8-41c3-9665-900c92d39bee	2	25322559	25322559	T	C	SNP	DNMT3A	NM_022552.3	human	genbank	54_36p	-1	reviewed	missense	c.1403	p.K468R	1.000	NULL	HMMPfam_PWWP,HMMSmart_SM00293,HMMPfam_DNA_methylase,superfamily_FYVE/PHD zinc finger,PatternScan_C5_MTASE_1,superfamily_S-adenosyl-L-methionine-dependent methyltransferases,superfamily_Tudor/PWWP/MBT	-	no_errors	84	1	1.16	22	10	31.25	27	3	10.00
IDH1	0	genome.wustl.edu	36	2	208821358	208821358	+	Missense_Mutation	SNP	G	G	A	rs121913499		TCGA-AB-2867-03B-01W-0728-08	TCGA-AB-2867-11B-01W-0729-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	b3f3ba24-dfbe-4b4b-8502-83ec6ecd7df3	4e18dd6e-74b8-41c3-9665-900c92d39bee	2	208821358	208821358	G	A	SNP	IDH1	NM_005896.2	human	genbank	54_36p	-1	reviewed	missense	c.394	p.R132C	1.000	HMMPfam_Iso_dh,superfamily_Isocitrate/Isopropylmalate dehydrogenase-like	HMMPfam_Iso_dh,PatternScan_IDH_IMDH,superfamily_Isocitrate/Isopropylmalate dehydrogenase-like	-	no_errors	115	4	3.31	48	29	37.66	17	22	56.41
KALRN	0	genome.wustl.edu	36	3	125706478	125706478	+	Silent	SNP	C	C	T			TCGA-AB-2867-03B-01W-0728-08	TCGA-AB-2867-11B-01W-0729-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	b3f3ba24-dfbe-4b4b-8502-83ec6ecd7df3	4e18dd6e-74b8-41c3-9665-900c92d39bee	3	125706478	125706478	C	T	SNP	KALRN	ENST00000393496	human	ensembl	54_36p	+1	known	silent	c.39	p.N13	1.000	superfamily_SH3	HMMPfam_RhoGEF,HMMSmart_RhoGEF,superfamily_DH-domain,HMMPfam_SH3_1,HMMSmart_SH3,superfamily_SH3,HMMPfam_PH,HMMSmart_PH,HMMPfam_SH3_2,superfamily_SSF50729	-	no_errors	260	7	2.61	123	58	31.69	NA	NA	NA
TUBA3C	0	genome.wustl.edu	36	13	18649388	18649388	+	Silent	SNP	G	G	A			TCGA-AB-2867-03B-01W-0728-08	TCGA-AB-2867-11B-01W-0729-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	b3f3ba24-dfbe-4b4b-8502-83ec6ecd7df3	4e18dd6e-74b8-41c3-9665-900c92d39bee	13	18649388	18649388	G	A	SNP	TUBA3C	NM_006001.1	human	genbank	54_36p	-1	reviewed	silent	c.735	p.D245	0.999	HMMPfam_Tubulin,superfamily_Tubulin nucleotide-binding domain-like	HMMPfam_Tubulin,superfamily_Tubulin C-terminal domain-like,PatternScan_TUBULIN,HMMPfam_Tubulin_C,superfamily_Tubulin nucleotide-binding domain-like	-	no_errors	123	3	2.36	37	22	37.29	NA	NA	NA
NALCN	0	genome.wustl.edu	36	13	100510315	100510315	+	Silent	SNP	C	C	T			TCGA-AB-2867-03B-01W-0728-08	TCGA-AB-2867-11B-01W-0729-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	b3f3ba24-dfbe-4b4b-8502-83ec6ecd7df3	4e18dd6e-74b8-41c3-9665-900c92d39bee	13	100510315	100510315	C	T	SNP	NALCN	NM_052867.2	human	genbank	54_36p	-1	validated	silent	c.4761	p.Q1587	1.000	NULL	HMMPfam_Ion_trans,superfamily_Voltage-gated potassium channels	-	no_errors	220	10	4.35	99	55	35.71	NA	NA	NA
OXA1L	0	genome.wustl.edu	36	14	22306396	22306396	+	Missense_Mutation	SNP	T	T	G			TCGA-AB-2867-03B-01W-0728-08	TCGA-AB-2867-11B-01W-0729-08	T	T	T	G	T	T	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	b3f3ba24-dfbe-4b4b-8502-83ec6ecd7df3	4e18dd6e-74b8-41c3-9665-900c92d39bee	14	22306396	22306396	T	G	SNP	OXA1L	NM_005015.3	human	genbank	54_36p	+1	validated	missense	c.343	p.F115V	0.001	NULL	HMMPfam_60KD_IMP	-	no_errors	107	2	1.83	43	19	30.65	65	37	36.27
NID2	0	genome.wustl.edu	36	14	51590184	51590184	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2867-03B-01W-0728-08	TCGA-AB-2867-11B-01W-0729-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	b3f3ba24-dfbe-4b4b-8502-83ec6ecd7df3	4e18dd6e-74b8-41c3-9665-900c92d39bee	14	51590184	51590184	G	A	SNP	NID2	NM_007361.3	human	genbank	54_36p	-1	validated	missense	c.1292	p.S431L	0.063	NULL	HMMPfam_Ldl_recept_b,HMMSmart_SM00135,PatternScan_ASX_HYDROXYL,HMMPfam_Thyroglobulin_1,HMMSmart_SM00211,PatternScan_THYROGLOBULIN_1_1,superfamily_Thyroglobulin type-1 domain,HMMSmart_SM00179,HMMPfam_NIDO,HMMSmart_SM00539,HMMPfam_EGF,HMMSmart_SM00181,HMMPfam_G2F,HMMSmart_SM00682,superfamily_GFP-like,PatternScan_EGF_2,HMMPfam_EGF_CA,PatternScan_EGF_CA,superfamily_EGF/Laminin,superfamily_YWTD domain	-	no_errors	206	3	1.43	190	58	23.20	NA	NA	NA
CENPN	0	genome.wustl.edu	36	16	79613724	79613724	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2867-03B-01W-0728-08	TCGA-AB-2867-11B-01W-0729-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	b3f3ba24-dfbe-4b4b-8502-83ec6ecd7df3	4e18dd6e-74b8-41c3-9665-900c92d39bee	16	79613724	79613724	C	T	SNP	CENPN	NM_001100625.1	human	genbank	54_36p	+1	validated	missense	c.553	p.H185Y	0.998	HMMPfam_CHL4	HMMPfam_CHL4	-	no_errors	160	5	3.01	74	39	34.51	0	0	0.00
RIBC2	0	genome.wustl.edu	36	22	44192246	44192246	+	Silent	SNP	G	G	A			TCGA-AB-2867-03B-01W-0728-08	TCGA-AB-2867-11B-01W-0729-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	b3f3ba24-dfbe-4b4b-8502-83ec6ecd7df3	4e18dd6e-74b8-41c3-9665-900c92d39bee	22	44192246	44192246	G	A	SNP	RIBC2	NM_015653.2	human	genbank	54_36p	+1	validated	silent	c.93	p.Q31	0.149	HMMPfam_RIB43A	HMMPfam_RIB43A	-	no_errors	232	10	4.08	120	85	41.46	0	3	100.00