Hugo_Symbol Entrez_Gene_Id Center NCBI_Build Chromosome Start_Position End_Position Strand Variant_Classification Variant_Type Reference_Allele Tumor_Seq_Allele1 Tumor_Seq_Allele2 dbSNP_RS dbSNP_Val_Status Tumor_Sample_Barcode Matched_Norm_Sample_Barcode Match_Norm_Seq_Allele1 Match_Norm_Seq_Allele2 Tumor_Validation_Allele1 Tumor_Validation_Allele2 Match_Norm_Validation_Allele1 Match_Norm_Validation_Allele2 Verification_Status Validation_Status Mutation_Status Sequencing_Phase Sequence_Source Validation_Method Score BAM_File Sequencer Tumor_Sample_UUID Matched_Norm_Sample_UUID chromosome_name start stop reference variant type gene_name transcript_name transcript_species transcript_source transcript_version strand transcript_status trv_type c_position amino_acid_change ucsc_cons domain all_domains deletion_substructures transcript_error NormalRefReads_WU NormalVarReads_WU NormalVAF_WU TumorRefReads_WU TumorVarReads_WU TumorVAF_WU RNARefReads_WU RNAVarReads_WU RNAVAF_WU IFI44 0 genome.wustl.edu 36 1 78897616 78897616 + Missense_Mutation SNP A A T TCGA-AB-2884-03A-01W-0732-08 TCGA-AB-2884-11A-01W-0732-08 A A A T A A Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 37c88c38-7f22-41c1-862c-6b9708c97d50 e592e767-0453-45cc-98a6-ba9ba48c6622 1 78897616 78897616 A T SNP IFI44 NM_006417.4 human genbank 54_36p +1 validated missense c.872 p.H291L 0.000 superfamily_SSF52540 superfamily_SSF52540 - no_errors 106 13 10.83 85 48 35.56 8 11 57.89 DNMT3A 0 genome.wustl.edu 36 2 25310746 25310746 + Missense_Mutation SNP C C T TCGA-AB-2884-03A-01W-0732-08 TCGA-AB-2884-11A-01W-0732-08 C C C T C C Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 37c88c38-7f22-41c1-862c-6b9708c97d50 e592e767-0453-45cc-98a6-ba9ba48c6622 2 25310746 25310746 C T SNP DNMT3A NM_022552.3 human genbank 54_36p -1 reviewed missense c.2645 p.R882H 1.000 superfamily_S-adenosyl-L-methionine-dependent methyltransferases HMMPfam_PWWP,HMMSmart_SM00293,HMMPfam_DNA_methylase,superfamily_FYVE/PHD zinc finger,PatternScan_C5_MTASE_1,superfamily_S-adenosyl-L-methionine-dependent methyltransferases,superfamily_Tudor/PWWP/MBT - no_errors 67 11 13.92 75 61 43.88 23 25 52.08 IDH1 0 genome.wustl.edu 36 2 208821357 208821357 + Missense_Mutation SNP C C T rs121913500 TCGA-AB-2884-03A-01W-0732-08 TCGA-AB-2884-11A-01W-0732-08 C C C T C C Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 37c88c38-7f22-41c1-862c-6b9708c97d50 e592e767-0453-45cc-98a6-ba9ba48c6622 2 208821357 208821357 C T SNP IDH1 NM_005896.2 human genbank 54_36p -1 reviewed missense c.395 p.R132H 1.000 HMMPfam_Iso_dh,superfamily_Isocitrate/Isopropylmalate dehydrogenase-like HMMPfam_Iso_dh,PatternScan_IDH_IMDH,superfamily_Isocitrate/Isopropylmalate dehydrogenase-like - no_errors 82 8 8.89 47 55 53.40 101 105 50.97 PTPN11 0 genome.wustl.edu 36 12 111372578 111372578 + Missense_Mutation SNP T T C TCGA-AB-2884-03A-01W-0732-08 TCGA-AB-2884-11A-01W-0732-08 T T T C T T Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 37c88c38-7f22-41c1-862c-6b9708c97d50 e592e767-0453-45cc-98a6-ba9ba48c6622 12 111372578 111372578 T C SNP PTPN11 NM_002834.3 human genbank 54_36p +1 reviewed missense c.211 p.F71L 1.000 HMMPfam_SH2,HMMSmart_SM00252,superfamily_SH2 domain HMMPfam_Y_phosphatase,HMMSmart_SM00194,HMMPfam_SH2,HMMSmart_SM00252,HMMSmart_SM00404,PatternScan_TYR_PHOSPHATASE_1,superfamily_(Phosphotyrosine protein) phosphatases II,superfamily_SH2 domain - no_errors 98 17 14.41 60 66 51.97 18 10 35.71 NPM1 0 genome.wustl.edu 36 5 170770148 170770149 + Frame_Shift_Ins INS - - TCTG TCGA-AB-2884-03A-01W-0732-08 TCGA-AB-2884-11A-01W-0732-08 - - - TCTG - - Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 37c88c38-7f22-41c1-862c-6b9708c97d50 e592e767-0453-45cc-98a6-ba9ba48c6622 5 170770148 170770149 - TCTG INS NPM1 NM_002520.1 human genbank 54_36p +1 validated frame_shift_ins c.859_860 p.W288fs 1.000:1.000 NULL HMMPfam_Nucleoplasmin,superfamily_Nucleoplasmin-like core domain - no_errors NA NA NA NA NA NA NA NA NA KCNK13 0 genome.wustl.edu 36 14 89721037 89721038 + Frame_Shift_Ins INS - - G TCGA-AB-2884-03A-01W-0732-08 TCGA-AB-2884-11A-01W-0732-08 - - - G - - Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 37c88c38-7f22-41c1-862c-6b9708c97d50 e592e767-0453-45cc-98a6-ba9ba48c6622 14 89721037 89721038 - G INS KCNK13 NM_022054.2 human genbank 54_36p +1 reviewed frame_shift_ins c.1164_1165 p.V390fs 0.880:1.000 NULL HMMPfam_Ion_trans_2,superfamily_Voltage-gated potassium channels - no_errors 29 0 0.00 42 4 8.70 0 0 0.00