Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	NormalRefReads_WU	NormalVarReads_WU	NormalVAF_WU	TumorRefReads_WU	TumorVarReads_WU	TumorVAF_WU	RNARefReads_WU	RNAVarReads_WU	RNAVAF_WU
PRDM16	0	genome.wustl.edu	36	1	3318383	3318383	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2895-03A-01W-0733-08	TCGA-AB-2895-11A-01W-0732-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	ced1c58f-9241-45ee-9f22-0bfa1554881e	ed37c4cc-1273-4e25-ba04-7d9bf757fffa	1	3318383	3318383	G	A	SNP	PRDM16	NM_022114.2	human	genbank	54_36p	+1	reviewed	missense	c.1762	p.V588M	0.001	NULL	HMMSmart_SM00317,HMMPfam_zf-C2H2,PatternScan_ZINC_FINGER_C2H2_1,HMMSmart_SM00355,superfamily_C2H2 and C2HC zinc fingers,superfamily_SET domain	-	no_errors	84	0	0.00	19	12	37.50	20	16	44.44
DCAF8	0	genome.wustl.edu	36	1	158476620	158476620	+	Missense_Mutation	SNP	A	A	G			TCGA-AB-2895-03A-01W-0733-08	TCGA-AB-2895-11A-01W-0732-08	A	A	A	G	A	A	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	ced1c58f-9241-45ee-9f22-0bfa1554881e	ed37c4cc-1273-4e25-ba04-7d9bf757fffa	1	158476620	158476620	A	G	SNP	WDR42A	NM_015726.2	human	genbank	54_36p	-1	reviewed	missense	c.214	p.S72P	1.000	NULL	HMMSmart_SM00320,superfamily_WD40 repeat-like,HMMPfam_WD40	-	no_errors	109	1	0.91	114	109	48.44	96	89	48.11
DNMT3A	0	genome.wustl.edu	36	2	25310746	25310746	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2895-03A-01W-0733-08	TCGA-AB-2895-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	ced1c58f-9241-45ee-9f22-0bfa1554881e	ed37c4cc-1273-4e25-ba04-7d9bf757fffa	2	25310746	25310746	C	T	SNP	DNMT3A	NM_022552.3	human	genbank	54_36p	-1	reviewed	missense	c.2645	p.R882H	1.000	superfamily_S-adenosyl-L-methionine-dependent methyltransferases	HMMPfam_PWWP,HMMSmart_SM00293,HMMPfam_DNA_methylase,superfamily_FYVE/PHD zinc finger,PatternScan_C5_MTASE_1,superfamily_S-adenosyl-L-methionine-dependent methyltransferases,superfamily_Tudor/PWWP/MBT	-	no_errors	130	0	0.00	18	16	47.06	39	58	59.18
SH3TC2	0	genome.wustl.edu	36	5	148386346	148386346	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2895-03A-01W-0733-08	TCGA-AB-2895-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	ced1c58f-9241-45ee-9f22-0bfa1554881e	ed37c4cc-1273-4e25-ba04-7d9bf757fffa	5	148386346	148386346	C	T	SNP	SH3TC2	NM_024577.3	human	genbank	54_36p	-1	reviewed	missense	c.3035	p.R1012Q	0.998	superfamily_TPR-like	HMMPfam_TPR_1,HMMPfam_SH3_1,HMMSmart_SM00326,superfamily_SH3-domain,HMMPfam_SH3_2,HMMSmart_SM00028,superfamily_TPR-like	-	no_errors	33	0	0.00	78	17	17.89	11	2	15.38
ATP10B	0	genome.wustl.edu	36	5	160045718	160045718	+	Missense_Mutation	SNP	T	T	C			TCGA-AB-2895-03A-01W-0733-08	TCGA-AB-2895-11A-01W-0732-08	T	T	T	C	T	T	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	ced1c58f-9241-45ee-9f22-0bfa1554881e	ed37c4cc-1273-4e25-ba04-7d9bf757fffa	5	160045718	160045718	T	C	SNP	ATP10B	NM_025153.2	human	genbank	54_36p	-1	validated	missense	c.416	p.K139R	0.985	HMMPfam_E1-E2_ATPase	HMMPfam_E1-E2_ATPase,HMMPfam_Hydrolase_3,PatternScan_ATPASE_E1_E2,superfamily_HAD-like,superfamily_Calcium ATPase transduction domain A,superfamily_Metal cation-transporting ATPase ATP-binding domain N	-	no_errors	114	1	0.85	114	65	36.31	NA	NA	NA
DOCK2	0	genome.wustl.edu	36	5	169058032	169058032	+	Splice_Site	SNP	G	G	A			TCGA-AB-2895-03A-01W-0733-08	TCGA-AB-2895-11A-01W-0732-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	ced1c58f-9241-45ee-9f22-0bfa1554881e	ed37c4cc-1273-4e25-ba04-7d9bf757fffa	5	169058032	169058032	G	A	SNP	DOCK2	NM_004946.2	human	genbank	54_36p	+1	validated	splice_site	c.1055+1	e11+1	1.000	-	-	-	no_errors	119	0	0.00	130	95	42.22	3	1	25.00
TBX18	0	genome.wustl.edu	36	6	85510728	85510728	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2895-03A-01W-0733-08	TCGA-AB-2895-11A-01W-0732-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	ced1c58f-9241-45ee-9f22-0bfa1554881e	ed37c4cc-1273-4e25-ba04-7d9bf757fffa	6	85510728	85510728	G	A	SNP	TBX18	NM_001080508.1	human	genbank	54_36p	-1	provisional	missense	c.974	p.A325V	1.000	HMMPfam_T-box,HMMSmart_TBOX,superfamily_P53_like_DNA_bnd	HMMPfam_T-box,HMMSmart_TBOX,superfamily_P53_like_DNA_bnd,PatternScan_TBOX_2,PatternScan_TBOX_1	-	no_errors	55	0	0.00	37	27	42.19	NA	NA	NA
DHX32	0	genome.wustl.edu	36	10	127559142	127559142	+	Missense_Mutation	SNP	A	A	G			TCGA-AB-2895-03A-01W-0733-08	TCGA-AB-2895-11A-01W-0732-08	A	A	A	G	A	A	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	ced1c58f-9241-45ee-9f22-0bfa1554881e	ed37c4cc-1273-4e25-ba04-7d9bf757fffa	10	127559142	127559142	A	G	SNP	DHX32	NM_018180.2	human	genbank	54_36p	-1	reviewed	missense	c.242	p.V81A	0.861	superfamily_P-loop containing nucleoside triphosphate hydrolases	HMMPfam_HA2,HMMPfam_DUF1605,superfamily_P-loop containing nucleoside triphosphate hydrolases	-	no_errors	78	0	0.00	52	42	44.68	15	18	54.55
LDLRAD3	0	genome.wustl.edu	36	11	36207460	36207460	+	Silent	SNP	C	C	T			TCGA-AB-2895-03A-01W-0733-08	TCGA-AB-2895-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	ced1c58f-9241-45ee-9f22-0bfa1554881e	ed37c4cc-1273-4e25-ba04-7d9bf757fffa	11	36207460	36207460	C	T	SNP	LDLRAD3	NM_174902.2	human	genbank	54_36p	+1	provisional	silent	c.975	p.G325	0.060	NULL	HMMPfam_Ldl_recept_a,HMMSmart_LDLa,PatternScan_LDLRA_1,superfamily_LDL_rcpt_classA_cys-rich	-	no_errors	28	0	0.00	21	11	34.38	0	1	100.00
TSKU	0	genome.wustl.edu	36	11	76184545	76184545	+	Silent	SNP	G	G	A			TCGA-AB-2895-03A-01W-0733-08	TCGA-AB-2895-11A-01W-0732-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	ced1c58f-9241-45ee-9f22-0bfa1554881e	ed37c4cc-1273-4e25-ba04-7d9bf757fffa	11	76184545	76184545	G	A	SNP	TSKU	NM_015516.3	human	genbank	54_36p	+1	validated	silent	c.237	p.A79	0.722	superfamily_SSF52047	HMMSmart_LRRNT,HMMPfam_LRR_1,HMMSmart_LRR_TYP,superfamily_SSF52047	-	no_errors	63	0	0.00	40	22	35.48	NA	NA	NA
CAND1	0	genome.wustl.edu	36	12	65986521	65986521	+	Missense_Mutation	SNP	T	T	G			TCGA-AB-2895-03A-01W-0733-08	TCGA-AB-2895-11A-01W-0732-08	T	T	T	G	T	T	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	ced1c58f-9241-45ee-9f22-0bfa1554881e	ed37c4cc-1273-4e25-ba04-7d9bf757fffa	12	65986521	65986521	T	G	SNP	CAND1	NM_018448.3	human	genbank	54_36p	+1	validated	missense	c.2806	p.L936V	0.998	superfamily_ARM repeat	HMMPfam_HEAT,HMMPfam_TIP120,superfamily_ARM repeat	-	no_errors	47	1	2.04	56	74	56.92	43	42	49.41
GUCY2D	0	genome.wustl.edu	36	17	7857964	7857964	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2895-03A-01W-0733-08	TCGA-AB-2895-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	ced1c58f-9241-45ee-9f22-0bfa1554881e	ed37c4cc-1273-4e25-ba04-7d9bf757fffa	17	7857964	7857964	C	T	SNP	GUCY2D	NM_000180.3	human	genbank	54_36p	+1	reviewed	missense	c.2305	p.P769S	1.000	superfamily_Kinase_like,HMMPfam_Pkinase	HMMPfam_Guanylate_cyc,HMMSmart_CYCc,superfamily_A/G_cyclase,HMMPfam_ANF_receptor,superfamily_Kinase_like,HMMPfam_Pkinase,PatternScan_GUANYLATE_CYCLASE_1,superfamily_SSF53822	-	no_errors	75	0	0.00	33	19	36.54	0	1	100.00
GAS7	0	genome.wustl.edu	36	17	9770743	9770743	+	Silent	SNP	G	G	A			TCGA-AB-2895-03A-01W-0733-08	TCGA-AB-2895-11A-01W-0732-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	ced1c58f-9241-45ee-9f22-0bfa1554881e	ed37c4cc-1273-4e25-ba04-7d9bf757fffa	17	9770743	9770743	G	A	SNP	GAS7	NM_201433.1	human	genbank	54_36p	-1	reviewed	silent	c.954	p.C318	0.891	NULL	HMMPfam_FCH,HMMSmart_SM00055,HMMPfam_WW,HMMSmart_SM00456,PatternScan_WW_DOMAIN_1,superfamily_WW domain,HMMPfam_SH3_1,HMMSmart_SM00326,superfamily_SH3-domain	-	no_errors	149	2	1.31	127	39	23.49	28	5	14.71
MED24	0	genome.wustl.edu	36	17	35443150	35443150	+	Silent	SNP	G	G	T			TCGA-AB-2895-03A-01W-0733-08	TCGA-AB-2895-11A-01W-0732-08	G	G	G	T	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	ced1c58f-9241-45ee-9f22-0bfa1554881e	ed37c4cc-1273-4e25-ba04-7d9bf757fffa	17	35443150	35443150	G	T	SNP	MED24	NM_014815.1	human	genbank	54_36p	-1	reviewed	silent	c.645	p.A215	0.346	NULL	NULL	-	no_errors	120	0	0.00	39	41	51.25	40	39	49.37
ALDH16A1	0	genome.wustl.edu	36	19	54657704	54657704	+	Silent	SNP	G	G	A			TCGA-AB-2895-03A-01W-0733-08	TCGA-AB-2895-11A-01W-0732-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	ced1c58f-9241-45ee-9f22-0bfa1554881e	ed37c4cc-1273-4e25-ba04-7d9bf757fffa	19	54657704	54657704	G	A	SNP	ALDH16A1	NM_153329.1	human	genbank	54_36p	+1	validated	silent	c.978	p.R326	0.406	HMMPfam_Aldedh,superfamily_ALDH-like	HMMPfam_Aldedh,superfamily_ALDH-like	-	no_errors	23	0	0.00	32	8	20.00	17	7	29.17
NPM1	0	genome.wustl.edu	36	5	170770148	170770149	+	Frame_Shift_Ins	INS	-	-	TCTG			TCGA-AB-2895-03A-01W-0733-08	TCGA-AB-2895-11A-01W-0732-08	-	-	-	TCTG	-	-	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	ced1c58f-9241-45ee-9f22-0bfa1554881e	ed37c4cc-1273-4e25-ba04-7d9bf757fffa	5	170770148	170770149	-	TCTG	INS	NPM1	NM_002520.1	human	genbank	54_36p	+1	validated	frame_shift_ins	c.859_860	p.W288fs	1.000:1.000	NULL	HMMPfam_Nucleoplasmin,superfamily_Nucleoplasmin-like core domain	-	no_errors	NA	NA	NA	NA	NA	NA	NA	NA	NA
FLT3	0	genome.wustl.edu	36	13	27506218	27506219	+	In_Frame_Ins	INS	-	-	CAAACTCTAAATTTTCTCTTGGAAACTCCCATTTGAGATCATATT			TCGA-AB-2895-03A-01W-0733-08	TCGA-AB-2895-11A-01W-0732-08	-	-	-	CAAACTCTAAATTTTCTCTTGGAAACTCCCATTTGAGATCATATT	-	-	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	ced1c58f-9241-45ee-9f22-0bfa1554881e	ed37c4cc-1273-4e25-ba04-7d9bf757fffa	13	27506218	27506219	-	CAAACTCTAAATTTTCTCTTGGAAACTCCCATTTGAGATCATATT	INS	FLT3	NM_004119.2	human	genbank	54_36p	-1	reviewed	in_frame_ins		in_frame_ins	1.000:1.000	-	-	-	no_errors	NA	NA	NA	NA	NA	NA	NA	NA	NA