Hugo_Symbol Entrez_Gene_Id Center NCBI_Build Chromosome Start_Position End_Position Strand Variant_Classification Variant_Type Reference_Allele Tumor_Seq_Allele1 Tumor_Seq_Allele2 dbSNP_RS dbSNP_Val_Status Tumor_Sample_Barcode Matched_Norm_Sample_Barcode Match_Norm_Seq_Allele1 Match_Norm_Seq_Allele2 Tumor_Validation_Allele1 Tumor_Validation_Allele2 Match_Norm_Validation_Allele1 Match_Norm_Validation_Allele2 Verification_Status Validation_Status Mutation_Status Sequencing_Phase Sequence_Source Validation_Method Score BAM_File Sequencer Tumor_Sample_UUID Matched_Norm_Sample_UUID chromosome_name start stop reference variant type gene_name transcript_name transcript_species transcript_source transcript_version strand transcript_status trv_type c_position amino_acid_change ucsc_cons domain all_domains deletion_substructures transcript_error NormalRefReads_WU NormalVarReads_WU NormalVAF_WU TumorRefReads_WU TumorVarReads_WU TumorVAF_WU RNARefReads_WU RNAVarReads_WU RNAVAF_WU DNMT3A 0 genome.wustl.edu 36 2 25310746 25310746 + Missense_Mutation SNP C C T TCGA-AB-2896-03A-01W-0733-08 TCGA-AB-2896-11A-01W-0732-08 C C C T C C Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 5af54c99-17a9-4dd6-9be1-45ac66819716 b49520b5-7cd3-48ff-aafa-c798a7637740 2 25310746 25310746 C T SNP DNMT3A NM_022552.3 human genbank 54_36p -1 reviewed missense c.2645 p.R882H 1.000 superfamily_S-adenosyl-L-methionine-dependent methyltransferases HMMPfam_PWWP,HMMSmart_SM00293,HMMPfam_DNA_methylase,superfamily_FYVE/PHD zinc finger,PatternScan_C5_MTASE_1,superfamily_S-adenosyl-L-methionine-dependent methyltransferases,superfamily_Tudor/PWWP/MBT - no_errors 53 28 34.15 29 22 43.14 43 56 56.00 NPM1 0 genome.wustl.edu 36 5 170770152 170770153 + Frame_Shift_Ins INS - - TCTG TCGA-AB-2896-03A-01W-0733-08 TCGA-AB-2896-11A-01W-0732-08 - - - TCTG - - Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 5af54c99-17a9-4dd6-9be1-45ac66819716 b49520b5-7cd3-48ff-aafa-c798a7637740 5 170770152 170770153 - TCTG INS NPM1 NM_002520.1 human genbank 54_36p +1 validated frame_shift_ins c.863_864 p.W288fs 1.000:1.000 NULL HMMPfam_Nucleoplasmin,superfamily_Nucleoplasmin-like core domain - no_errors NA NA NA NA NA NA NA NA NA SLC39A5 0 genome.wustl.edu 36 12 54917282 54917283 + Frame_Shift_Ins INS - - G TCGA-AB-2896-03A-01W-0733-08 TCGA-AB-2896-11A-01W-0732-08 - - - G - - Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 5af54c99-17a9-4dd6-9be1-45ac66819716 b49520b5-7cd3-48ff-aafa-c798a7637740 12 54917282 54917283 - G INS SLC39A5 NM_173596.1 human genbank 54_36p +1 validated frame_shift_ins c.1367_1368 p.A459fs 0.797:0.707 HMMPfam_Zip HMMPfam_Zip - no_errors 33 0 0.00 27 4 12.90 2 0 0.00