Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	NormalRefReads_WU	NormalVarReads_WU	NormalVAF_WU	TumorRefReads_WU	TumorVarReads_WU	TumorVAF_WU	RNARefReads_WU	RNAVarReads_WU	RNAVAF_WU
PEAR1	0	genome.wustl.edu	36	1	155141762	155141762	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2920-03A-01W-0732-08	TCGA-AB-2920-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	03508d3a-3bc2-4ec1-91cd-80a9f5aadad5	4ab04cad-cee0-4f9f-80b7-66d2472f5e31	1	155141762	155141762	C	T	SNP	PEAR1	NM_001080471.1	human	genbank	54_36p	+1	provisional	missense	c.229	p.R77C	0.994	HMMPfam_EMI	HMMPfam_Laminin_EGF,HMMSmart_EGF_Lam,HMMSmart_EGF,superfamily_Grow_fac_recept,HMMPfam_EMI,PatternScan_EGF_1,PatternScan_EGF_2,HMMPfam_EGF_2	-	no_errors	59	1	1.67	96	75	43.86	1	1	50.00
MAL	0	genome.wustl.edu	36	2	95079067	95079067	+	Silent	SNP	C	C	T			TCGA-AB-2920-03A-01W-0732-08	TCGA-AB-2920-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	03508d3a-3bc2-4ec1-91cd-80a9f5aadad5	4ab04cad-cee0-4f9f-80b7-66d2472f5e31	2	95079067	95079067	C	T	SNP	MAL	NM_002371.2	human	genbank	54_36p	+1	reviewed	silent	c.276	p.H92	0.425	HMMPfam_MARVEL	HMMPfam_MARVEL	-	no_errors	20	2	9.09	46	36	43.37	15	0	0.00
ABCF1	0	genome.wustl.edu	36	6	30662408	30662408	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2920-03A-01W-0732-08	TCGA-AB-2920-11A-01W-0732-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	03508d3a-3bc2-4ec1-91cd-80a9f5aadad5	4ab04cad-cee0-4f9f-80b7-66d2472f5e31	6	30662408	30662408	G	A	SNP	ABCF1	NM_001025091.1	human	genbank	54_36p	+1	reviewed	missense	c.1972	p.G658S	1.000	HMMPfam_ABC_tran,HMMSmart_SM00382,superfamily_P-loop containing nucleoside triphosphate hydrolases	HMMPfam_ABC_tran,HMMSmart_SM00382,PatternScan_ABC_TRANSPORTER_1,superfamily_P-loop containing nucleoside triphosphate hydrolases	-	no_errors	238	19	7.39	281	199	40.95	22	36	62.07
VARS2	0	genome.wustl.edu	36	6	30994596	30994596	+	Silent	SNP	G	G	A			TCGA-AB-2920-03A-01W-0732-08	TCGA-AB-2920-11A-01W-0732-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	03508d3a-3bc2-4ec1-91cd-80a9f5aadad5	4ab04cad-cee0-4f9f-80b7-66d2472f5e31	6	30994596	30994596	G	A	SNP	VARS2	NM_020442.3	human	genbank	54_36p	+1	provisional	silent	c.999	p.V333	0.615	HMMPfam_tRNA-synt_1,superfamily_ValRS/IleRS/LeuRS editing domain,superfamily_Nucleotidylyl transferase	PatternScan_AA_TRNA_LIGASE_I,HMMPfam_tRNA-synt_1,superfamily_ValRS/IleRS/LeuRS editing domain,superfamily_Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases,HMMPfam_Anticodon_1,superfamily_Nucleotidylyl transferase	-	no_errors	71	7	8.97	123	112	47.26	49	62	55.86
ACTL7A	0	genome.wustl.edu	36	9	110665699	110665699	+	Missense_Mutation	SNP	G	G	C			TCGA-AB-2920-03A-01W-0732-08	TCGA-AB-2920-11A-01W-0732-08	G	G	G	C	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	03508d3a-3bc2-4ec1-91cd-80a9f5aadad5	4ab04cad-cee0-4f9f-80b7-66d2472f5e31	9	110665699	110665699	G	C	SNP	ACTL7A	NM_006687.2	human	genbank	54_36p	+1	reviewed	missense	c.1276	p.G426R	1.000	HMMPfam_Actin,HMMSmart_SM00268,superfamily_Actin-like ATPase domain	HMMPfam_Actin,HMMSmart_SM00268,superfamily_Actin-like ATPase domain	-	no_errors	37	1	2.63	61	67	52.34	NA	NA	NA
FAM166A	0	genome.wustl.edu	36	9	139259932	139259932	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2920-03A-01W-0732-08	TCGA-AB-2920-11A-01W-0732-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	03508d3a-3bc2-4ec1-91cd-80a9f5aadad5	4ab04cad-cee0-4f9f-80b7-66d2472f5e31	9	139259932	139259932	G	A	SNP	FAM166A	NM_001001710.1	human	genbank	54_36p	-1	predicted	missense	c.251	p.P84L	0.990	NULL	HMMPfam_DUF2475	-	no_errors	6	0	0.00	1	4	80.00	0	1	100.00
KCNA4	0	genome.wustl.edu	36	11	29990509	29990509	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2920-03A-01W-0732-08	TCGA-AB-2920-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	03508d3a-3bc2-4ec1-91cd-80a9f5aadad5	4ab04cad-cee0-4f9f-80b7-66d2472f5e31	11	29990509	29990509	C	T	SNP	KCNA4	NM_002233.2	human	genbank	54_36p	-1	reviewed	missense	c.293	p.R98Q	0.941	NULL	HMMSmart_SM00225,HMMPfam_K_tetra,HMMPfam_Ion_trans,superfamily_POZ domain,HMMPfam_K_channel_TID,superfamily_Voltage-gated potassium channels	-	no_errors	112	8	6.61	118	113	48.50	NA	NA	NA
ENSG00000204989	0	genome.wustl.edu	36	11	59016357	59016357	+	Missense_Mutation	SNP	G	G	T			TCGA-AB-2920-03A-01W-0732-08	TCGA-AB-2920-11A-01W-0732-08	G	G	G	T	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	03508d3a-3bc2-4ec1-91cd-80a9f5aadad5	4ab04cad-cee0-4f9f-80b7-66d2472f5e31	11	59016357	59016357	G	T	SNP	ENSG00000204989	ENST00000378245	human	ensembl	54_36p	+1	known	missense	c.552	p.M184I	0.000	HMMPfam_7tm_1,superfamily_SSF81321	HMMPfam_7tm_1,superfamily_SSF81321	-	no_errors	139	7	4.79	155	111	40.81	NA	NA	NA
OR3A2	0	genome.wustl.edu	36	17	3128252	3128252	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2920-03A-01W-0732-08	TCGA-AB-2920-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	03508d3a-3bc2-4ec1-91cd-80a9f5aadad5	4ab04cad-cee0-4f9f-80b7-66d2472f5e31	17	3128252	3128252	C	T	SNP	OR3A2	NM_002551.3	human	genbank	54_36p	-1	validated	missense	c.728	p.R243Q	0.004	HMMPfam_7tm_1,superfamily_SSF81321	HMMPfam_7tm_1,PatternScan_G_PROTEIN_RECEP_F1_1,superfamily_SSF81321	-	no_errors	69	0	0.00	175	24	11.88	NA	NA	NA
NF1	0	genome.wustl.edu	36	17	26586873	26586873	+	Missense_Mutation	SNP	G	G	A	rs137854556		TCGA-AB-2920-03A-01W-0732-08	TCGA-AB-2920-11A-01W-0732-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	03508d3a-3bc2-4ec1-91cd-80a9f5aadad5	4ab04cad-cee0-4f9f-80b7-66d2472f5e31	17	26586873	26586873	G	A	SNP	NF1	NM_001042492.2	human	genbank	54_36p	+1	reviewed	missense	c.3827	p.R1276Q	1.000	HMMPfam_RasGAP,HMMSmart_SM00323,superfamily_GTPase activation domain GAP	HMMSmart_SM00516,HMMPfam_RasGAP,HMMSmart_SM00323,PatternScan_RAS_GTPASE_ACTIV_1,superfamily_GTPase activation domain GAP	-	no_errors	66	4	5.71	28	97	77.60	0	11	100.00
ARHGEF1	0	genome.wustl.edu	36	19	47101973	47101973	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2920-03A-01W-0732-08	TCGA-AB-2920-11A-01W-0732-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	03508d3a-3bc2-4ec1-91cd-80a9f5aadad5	4ab04cad-cee0-4f9f-80b7-66d2472f5e31	19	47101973	47101973	G	A	SNP	ARHGEF1	NM_199002.3	human	genbank	54_36p	+1	reviewed	missense	c.2492	p.R831K	1.000	NULL	HMMPfam_RhoGEF,HMMSmart_RhoGEF,superfamily_DH-domain,HMMSmart_PH,HMMPfam_RGS-like,superfamily_Regulat_G_prot_signal_superfam,superfamily_SSF50729	-	no_errors	36	2	5.26	43	25	35.71	275	212	43.44
CBX7	0	genome.wustl.edu	36	22	37864635	37864636	+	Frame_Shift_Ins	INS	-	-	GCTC			TCGA-AB-2920-03A-01W-0732-08	TCGA-AB-2920-11A-01W-0732-08	-	-	-	GCTC	-	-	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	03508d3a-3bc2-4ec1-91cd-80a9f5aadad5	4ab04cad-cee0-4f9f-80b7-66d2472f5e31	22	37864635	37864636	-	GCTC	INS	CBX7	NM_175709.3	human	genbank	54_36p	-1	validated	frame_shift_ins	c.198_197	p.G68fs	0.981:0.999	NULL	HMMPfam_Chromo,HMMSmart_CHROMO,PatternScan_CHROMO_1,superfamily_Chromodomain-like	-	no_errors	NA	NA	NA	NA	NA	NA	NA	NA	NA
CBX7	0	genome.wustl.edu	36	22	37864636	37864637	+	Frame_Shift_Ins	INS	-	-	GCTC			TCGA-AB-2920-03A-01W-0732-08	TCGA-AB-2920-11A-01W-0732-08	-	-	-	GCTC	-	-	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	03508d3a-3bc2-4ec1-91cd-80a9f5aadad5	4ab04cad-cee0-4f9f-80b7-66d2472f5e31	22	37864636	37864637	-	GCTC	INS	CBX7	NM_175709.3	human	genbank	54_36p	-1	validated	frame_shift_ins	c.197_196	p.A66fs	0.999:1.000	NULL	HMMPfam_Chromo,HMMSmart_CHROMO,PatternScan_CHROMO_1,superfamily_Chromodomain-like	-	no_errors	NA	NA	NA	NA	NA	NA	NA	NA	NA