Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	NormalRefReads_WU	NormalVarReads_WU	NormalVAF_WU	TumorRefReads_WU	TumorVarReads_WU	TumorVAF_WU	RNARefReads_WU	RNAVarReads_WU	RNAVAF_WU
DDX53	0	genome.wustl.edu	36	X	22928217	22928217	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2926-03A-01W-0732-08	TCGA-AB-2926-11A-01W-0761-09	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	890ea799-3156-40c3-839c-0c60179006d7	04ea59bd-4188-4b75-ae4b-4f8f3665db56	X	22928217	22928217	C	T	SNP	DDX53	NM_182699.2	human	genbank	54_36p	+1	validated	missense	c.122	p.P41L	0.001	superfamily_SSF54791	PatternScan_DEAD_ATP_HELICASE,HMMPfam_Helicase_C,HMMSmart_HELICc,HMMSmart_KH,HMMPfam_DEAD,HMMSmart_DEXDc,HMMPfam_KH_1,superfamily_SSF52540,superfamily_SSF54791	-	no_errors	74	5	6.33	40	35	46.67	NA	NA	NA
RBBP4	0	genome.wustl.edu	36	1	32910659	32910659	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2926-03A-01W-0732-08	TCGA-AB-2926-11A-01W-0761-09	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	890ea799-3156-40c3-839c-0c60179006d7	04ea59bd-4188-4b75-ae4b-4f8f3665db56	1	32910659	32910659	G	A	SNP	RBBP4	NM_005610.1	human	genbank	54_36p	+1	reviewed	missense	c.988	p.E330K	1.000	HMMSmart_SM00320,superfamily_WD40 repeat-like,HMMPfam_WD40	HMMSmart_SM00320,superfamily_WD40 repeat-like,PatternScan_WD_REPEATS_1,HMMPfam_WD40	-	no_errors	132	9	6.34	103	84	44.21	NA	NA	NA
ZNF642	0	genome.wustl.edu	36	1	40734107	40734107	+	Missense_Mutation	SNP	A	A	G			TCGA-AB-2926-03A-01W-0732-08	TCGA-AB-2926-11A-01W-0761-09	A	A	A	G	A	A	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	890ea799-3156-40c3-839c-0c60179006d7	04ea59bd-4188-4b75-ae4b-4f8f3665db56	1	40734107	40734107	A	G	SNP	ZNF642	NM_198494.2	human	genbank	54_36p	+1	validated	missense	c.1370	p.H457R	0.957	HMMPfam_zf-C2H2,PatternScan_ZINC_FINGER_C2H2_1,HMMSmart_ZnF_C2H2,superfamily_SSF57667	HMMPfam_KRAB,HMMSmart_KRAB,superfamily_Krueppel-associated_box,HMMPfam_zf-C2H2,PatternScan_ZINC_FINGER_C2H2_1,HMMSmart_ZnF_C2H2,superfamily_SSF57667	-	no_errors	109	15	12.00	45	55	55.00	NA	NA	NA
GCLM	0	genome.wustl.edu	36	1	94134956	94134956	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2926-03A-01W-0732-08	TCGA-AB-2926-11A-01W-0761-09	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	890ea799-3156-40c3-839c-0c60179006d7	04ea59bd-4188-4b75-ae4b-4f8f3665db56	1	94134956	94134956	C	T	SNP	GCLM	NM_002061.2	human	genbank	54_36p	-1	reviewed	missense	c.346	p.V116I	0.981	superfamily_NAD(P)-linked oxidoreductase	HMMPfam_Aldo_ket_red,superfamily_NAD(P)-linked oxidoreductase	-	no_errors	83	4	4.49	59	26	30.59	NA	NA	NA
ITGAV	0	genome.wustl.edu	36	2	187195324	187195324	+	Nonsense_Mutation	SNP	T	T	A			TCGA-AB-2926-03A-01W-0732-08	TCGA-AB-2926-11A-01W-0761-09	T	T	T	A	T	T	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	890ea799-3156-40c3-839c-0c60179006d7	04ea59bd-4188-4b75-ae4b-4f8f3665db56	2	187195324	187195324	T	A	SNP	ITGAV	NM_002210.1	human	genbank	54_36p	+1	reviewed	nonsense	c.330	p.Y110*	1.000	superfamily_Integrin alpha N-terminal domain	HMMPfam_Integrin_alpha,HMMPfam_FG-GAP,HMMSmart_SM00191,HMMPfam_Integrin_alpha2,PatternScan_INTEGRIN_ALPHA,superfamily_Integrin domains,superfamily_Integrin alpha N-terminal domain	-	no_errors	202	20	9.01	130	77	36.84	NA	NA	NA
IDH1	0	genome.wustl.edu	36	2	208821358	208821358	+	Missense_Mutation	SNP	G	G	A	rs121913499		TCGA-AB-2926-03A-01W-0732-08	TCGA-AB-2926-11A-01W-0761-09	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	890ea799-3156-40c3-839c-0c60179006d7	04ea59bd-4188-4b75-ae4b-4f8f3665db56	2	208821358	208821358	G	A	SNP	IDH1	NM_005896.2	human	genbank	54_36p	-1	reviewed	missense	c.394	p.R132C	1.000	HMMPfam_Iso_dh,superfamily_Isocitrate/Isopropylmalate dehydrogenase-like	HMMPfam_Iso_dh,PatternScan_IDH_IMDH,superfamily_Isocitrate/Isopropylmalate dehydrogenase-like	-	no_errors	81	5	5.81	50	55	51.89	NA	NA	NA
CXCL10	0	genome.wustl.edu	36	4	77162918	77162918	+	Silent	SNP	T	T	C			TCGA-AB-2926-03A-01W-0732-08	TCGA-AB-2926-11A-01W-0761-09	T	T	T	C	T	T	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	890ea799-3156-40c3-839c-0c60179006d7	04ea59bd-4188-4b75-ae4b-4f8f3665db56	4	77162918	77162918	T	C	SNP	CXCL10	NM_001565.2	human	genbank	54_36p	-1	reviewed	silent	c.138	p.E46	0.669	HMMPfam_IL8,HMMSmart_SCY,superfamily_Chemokine_IL8,PatternScan_SMALL_CYTOKINES_CXC	HMMPfam_IL8,HMMSmart_SCY,superfamily_Chemokine_IL8,PatternScan_SMALL_CYTOKINES_CXC	-	no_errors	213	25	10.29	106	84	44.21	NA	NA	NA
KIF27	0	genome.wustl.edu	36	9	85707986	85707986	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2926-03A-01W-0732-08	TCGA-AB-2926-11A-01W-0761-09	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	890ea799-3156-40c3-839c-0c60179006d7	04ea59bd-4188-4b75-ae4b-4f8f3665db56	9	85707986	85707986	C	T	SNP	KIF27	NM_017576.1	human	genbank	54_36p	-1	provisional	missense	c.1267	p.V423I	0.878	NULL	HMMPfam_Kinesin,HMMSmart_SM00129,PatternScan_KINESIN_MOTOR_DOMAIN1,superfamily_P-loop containing nucleoside triphosphate hydrolases	-	no_errors	176	17	8.72	106	67	38.73	NA	NA	NA
SBF2	0	genome.wustl.edu	36	11	9970647	9970647	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2926-03A-01W-0732-08	TCGA-AB-2926-11A-01W-0761-09	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	890ea799-3156-40c3-839c-0c60179006d7	04ea59bd-4188-4b75-ae4b-4f8f3665db56	11	9970647	9970647	C	T	SNP	SBF2	NM_030962.3	human	genbank	54_36p	-1	reviewed	missense	c.1187	p.R396H	1.000	HMMPfam_dDENN,HMMSmart_SM00801	HMMPfam_DENN,HMMSmart_SM00799,HMMPfam_PH,HMMSmart_SM00233,HMMPfam_GRAM,HMMSmart_SM00568,HMMPfam_dDENN,HMMSmart_SM00801,HMMPfam_uDENN,HMMSmart_SM00800,HMMPfam_Myotub-related,superfamily_PH domain-like,superfamily_(Phosphotyrosine protein) phosphatases II	-	no_errors	89	5	5.26	61	56	47.46	NA	NA	NA
WNK1	0	genome.wustl.edu	36	12	840502	840502	+	Missense_Mutation	SNP	A	A	C			TCGA-AB-2926-03A-01W-0732-08	TCGA-AB-2926-11A-01W-0761-09	A	A	A	C	A	A	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	890ea799-3156-40c3-839c-0c60179006d7	04ea59bd-4188-4b75-ae4b-4f8f3665db56	12	840502	840502	A	C	SNP	WNK1	NM_018979.2	human	genbank	54_36p	+1	validated	missense	c.1683	p.R561S	0.989	superfamily_Kinase_like	PatternScan_PROTEIN_KINASE_ST,superfamily_Kinase_like,HMMPfam_Pkinase	-	no_errors	120	7	5.47	64	41	38.32	NA	NA	NA
FLT3	0	genome.wustl.edu	36	13	27490642	27490642	+	Missense_Mutation	SNP	C	C	A	rs121913488		TCGA-AB-2926-03A-01W-0732-08	TCGA-AB-2926-11A-01W-0761-09	C	C	C	A	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	890ea799-3156-40c3-839c-0c60179006d7	04ea59bd-4188-4b75-ae4b-4f8f3665db56	13	27490642	27490642	C	A	SNP	FLT3	NM_004119.2	human	genbank	54_36p	-1	reviewed	missense	c.2503	p.D835Y	1.000	HMMPfam_Pkinase_Tyr,HMMSmart_TyrKc,superfamily_Kinase_like	HMMPfam_Pkinase_Tyr,HMMSmart_TyrKc,PatternScan_RECEPTOR_TYR_KIN_III,PatternScan_PROTEIN_KINASE_TYR,superfamily_Kinase_like,HMMPfam_ig,PatternScan_PROTEIN_KINASE_ATP,superfamily_SSF48726	-	no_errors	94	2	2.06	77	44	36.36	NA	NA	NA
AKAP5	0	genome.wustl.edu	36	14	64005169	64005169	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2926-03A-01W-0732-08	TCGA-AB-2926-11A-01W-0761-09	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	890ea799-3156-40c3-839c-0c60179006d7	04ea59bd-4188-4b75-ae4b-4f8f3665db56	14	64005169	64005169	G	A	SNP	AKAP5	NM_004857.3	human	genbank	54_36p	+1	reviewed	missense	c.304	p.E102K	0.265	HMMPfam_WSK	HMMPfam_WSK,HMMPfam_RII_binding_1	-	no_errors	54	5	8.33	35	22	38.60	NA	NA	NA
MIR142	0	genome.wustl.edu	36	17	53763622	53763622	+	RNA	SNP	A	A	G			TCGA-AB-2926-03A-01W-0732-08	TCGA-AB-2926-11A-01W-0761-09	A	A	A	G	A	A	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	890ea799-3156-40c3-839c-0c60179006d7	04ea59bd-4188-4b75-ae4b-4f8f3665db56	17	53763622	53763622	A	G	SNP	MIRN142	ENST00000384835	human	ensembl	54_36p	-1	known	rna	NULL	NULL	1.000	-	-	-	no_errors	61	2	3.12	48	30	37.97	NA	NA	NA
DDX17	0	genome.wustl.edu	36	22	37224035	37224035	+	Splice_Site	SNP	C	C	T			TCGA-AB-2926-03A-01W-0732-08	TCGA-AB-2926-11A-01W-0761-09	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	890ea799-3156-40c3-839c-0c60179006d7	04ea59bd-4188-4b75-ae4b-4f8f3665db56	22	37224035	37224035	C	T	SNP	DDX17	NM_001098504.1	human	genbank	54_36p	-1	reviewed	splice_site	c.738+1	e5+1	1.000	-	-	-	no_errors	133	8	5.48	90	75	44.64	NA	NA	NA
SHC1	0	genome.wustl.edu	36	1	153209534	153209535	+	Frame_Shift_Ins	INS	-	-	G			TCGA-AB-2926-03A-01W-0732-08	TCGA-AB-2926-11A-01W-0761-09	-	-	-	G	-	-	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	890ea799-3156-40c3-839c-0c60179006d7	04ea59bd-4188-4b75-ae4b-4f8f3665db56	1	153209534	153209535	-	G	INS	SHC1	NM_183001.1	human	genbank	54_36p	-1	validated	frame_shift_ins	c.93_92	p.E32fs	1.000:1.000	NULL	HMMPfam_SH2,HMMSmart_SM00252,HMMPfam_PID,HMMSmart_SM00462,superfamily_PH domain-like,superfamily_SH2 domain	-	no_errors	19	0	0.00	25	3	10.71	NA	NA	NA
STC2	0	genome.wustl.edu	36	5	172677531	172677532	+	Frame_Shift_Ins	INS	-	-	C			TCGA-AB-2926-03A-01W-0732-08	TCGA-AB-2926-11A-01W-0761-09	-	-	-	C	-	-	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	890ea799-3156-40c3-839c-0c60179006d7	04ea59bd-4188-4b75-ae4b-4f8f3665db56	5	172677531	172677532	-	C	INS	STC2	NM_003714.2	human	genbank	54_36p	-1	reviewed	frame_shift_ins	c.834_833	p.L279fs	0.011:0.001	NULL	HMMPfam_Stanniocalcin	-	no_errors	32	0	0.00	39	3	7.14	NA	NA	NA