Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	NormalRefReads_WU	NormalVarReads_WU	NormalVAF_WU	TumorRefReads_WU	TumorVarReads_WU	TumorVAF_WU	RNARefReads_WU	RNAVarReads_WU	RNAVAF_WU
SYTL5	0	genome.wustl.edu	36	X	37820855	37820855	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2929-03A-01W-0732-08	TCGA-AB-2929-11A-01W-0732-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	3ca5c769-b07c-4a68-818d-ab2bb8141170	0aa884ea-58b7-4079-a204-be6fe7e90a24	X	37820855	37820855	G	A	SNP	SYTL5	NM_138780.1	human	genbank	54_36p	+1	provisional	missense	c.646	p.G216S	0.109	HMMPfam_RPH3A_effector	HMMPfam_C2,HMMSmart_C2,HMMPfam_RPH3A_effector,superfamily_C2_CaLB,superfamily_FYVE_PHD_ZnF	-	no_errors	84	4	4.55	131	77	36.84	NA	NA	NA
LOC644504	0	genome.wustl.edu	36	X	105457450	105457450	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2929-03A-01W-0732-08	TCGA-AB-2929-11A-01W-0732-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	3ca5c769-b07c-4a68-818d-ab2bb8141170	0aa884ea-58b7-4079-a204-be6fe7e90a24	X	105457450	105457450	G	A	SNP	LOC644504	XM_001128075.1	human	genbank	54_36p	+1	model	missense	c.25	p.E9K	1.000	HMMPfam_CHGN,superfamily_Nucleotide-diphospho-sugar transferases	HMMPfam_CHGN,superfamily_Nucleotide-diphospho-sugar transferases	-	no_errors	73	2	2.63	35	67	64.42	9	0	0.00
BRCC3	0	genome.wustl.edu	36	X	153958684	153958684	+	Nonsense_Mutation	SNP	C	C	T			TCGA-AB-2929-03A-01W-0732-08	TCGA-AB-2929-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	3ca5c769-b07c-4a68-818d-ab2bb8141170	0aa884ea-58b7-4079-a204-be6fe7e90a24	X	153958684	153958684	C	T	SNP	BRCC3	NM_024332.1	human	genbank	54_36p	+1	reviewed	nonsense	c.241	p.R81*	1.000	HMMPfam_Mov34,HMMSmart_SM00232,superfamily_JAB1/MPN domain	HMMPfam_Mov34,HMMSmart_SM00232,superfamily_JAB1/MPN domain	-	no_errors	96	5	4.90	48	61	54.95	1	11	91.67
SYPL2	0	genome.wustl.edu	36	1	109821023	109821023	+	Silent	SNP	G	G	A			TCGA-AB-2929-03A-01W-0732-08	TCGA-AB-2929-11A-01W-0732-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	3ca5c769-b07c-4a68-818d-ab2bb8141170	0aa884ea-58b7-4079-a204-be6fe7e90a24	1	109821023	109821023	G	A	SNP	SYPL2	NM_001040709.1	human	genbank	54_36p	+1	validated	silent	c.357	p.V119	1.000	HMMPfam_MARVEL	HMMPfam_MARVEL	-	no_errors	82	5	5.75	145	81	35.53	NA	NA	NA
NTSR2	0	genome.wustl.edu	36	2	11717629	11717629	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2929-03A-01W-0732-08	TCGA-AB-2929-11A-01W-0732-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	3ca5c769-b07c-4a68-818d-ab2bb8141170	0aa884ea-58b7-4079-a204-be6fe7e90a24	2	11717629	11717629	G	A	SNP	NTSR2	NM_012344.3	human	genbank	54_36p	-1	reviewed	missense	c.980	p.A327V	0.001	HMMPfam_7tm_1,superfamily_Family A G protein-coupled receptor-like	HMMPfam_7tm_1,PatternScan_G_PROTEIN_RECEP_F1_1,superfamily_Family A G protein-coupled receptor-like	-	no_errors	47	0	0.00	71	26	26.26	NA	NA	NA
SF3B1	0	genome.wustl.edu	36	2	197975079	197975079	+	Missense_Mutation	SNP	T	T	C			TCGA-AB-2929-03A-01W-0732-08	TCGA-AB-2929-11A-01W-0732-08	T	T	T	C	T	T	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	3ca5c769-b07c-4a68-818d-ab2bb8141170	0aa884ea-58b7-4079-a204-be6fe7e90a24	2	197975079	197975079	T	C	SNP	SF3B1	NM_012433.1	human	genbank	54_36p	-1	reviewed	missense	c.2098	p.K700E	1.000	HMMPfam_HEAT,superfamily_ARM repeat	HMMPfam_HEAT,HMMPfam_SF3b1,superfamily_ARM repeat	-	no_errors	44	0	0.00	57	57	49.57	291	258	46.99
ENSG00000214135	0	genome.wustl.edu	36	3	196875734	196875734	+	Missense_Mutation	SNP	A	A	G			TCGA-AB-2929-03A-01W-0732-08	TCGA-AB-2929-11A-01W-0732-08	A	A	A	G	A	A	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	3ca5c769-b07c-4a68-818d-ab2bb8141170	0aa884ea-58b7-4079-a204-be6fe7e90a24	3	196875734	196875734	A	G	SNP	ENSG00000214135	ENST00000397590	human	ensembl	54_36p	+1	known	missense	c.194	p.Y65C	1.000	HMMPfam_FAD_binding_2,superfamily_SSF51905	HMMPfam_FAD_binding_2,HMMPfam_Succ_DH_flav_C,superfamily_Succ_DH_flav_C,superfamily_SSF51905,superfamily_SSF56425	-	no_start_codon:no_stop_codon	8	0	0.00	15	7	31.82	4	0	0.00
CD74	0	genome.wustl.edu	36	5	149764445	149764445	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2929-03A-01W-0732-08	TCGA-AB-2929-11A-01W-0732-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	3ca5c769-b07c-4a68-818d-ab2bb8141170	0aa884ea-58b7-4079-a204-be6fe7e90a24	5	149764445	149764445	G	A	SNP	CD74	NM_001025159.1	human	genbank	54_36p	-1	validated	missense	c.616	p.P206S	0.002	superfamily_Thyroglobulin type-1 domain,HMMPfam_MHCassoc_trimer,superfamily_Class II MHC-associated invariant chain ectoplasmic trimerization domain	HMMPfam_Thyroglobulin_1,HMMSmart_SM00211,PatternScan_THYROGLOBULIN_1_1,superfamily_Thyroglobulin type-1 domain,HMMPfam_MHCassoc_trimer,superfamily_Class II MHC-associated invariant chain ectoplasmic trimerization domain,HMMPfam_MHC2-interact	-	no_errors	53	2	3.57	68	49	41.53	1915	2008	51.11
HIVEP1	0	genome.wustl.edu	36	6	12233870	12233870	+	Silent	SNP	G	G	A			TCGA-AB-2929-03A-01W-0732-08	TCGA-AB-2929-11A-01W-0732-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	3ca5c769-b07c-4a68-818d-ab2bb8141170	0aa884ea-58b7-4079-a204-be6fe7e90a24	6	12233870	12233870	G	A	SNP	HIVEP1	NM_002114.2	human	genbank	54_36p	+1	validated	silent	c.5856	p.S1952	0.006	NULL	HMMPfam_zf-C2H2,PatternScan_ZINC_FINGER_C2H2_1,HMMSmart_SM00355,superfamily_C2H2 and C2HC zinc fingers	-	no_errors	41	1	2.38	50	30	37.50	10	6	37.50
TNC	0	genome.wustl.edu	36	9	116843181	116843181	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2929-03A-01W-0732-08	TCGA-AB-2929-11A-01W-0732-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	3ca5c769-b07c-4a68-818d-ab2bb8141170	0aa884ea-58b7-4079-a204-be6fe7e90a24	9	116843181	116843181	G	A	SNP	TNC	NM_002160.2	human	genbank	54_36p	-1	validated	missense	c.5252	p.T1751I	0.001	HMMPfam_fn3,HMMSmart_FN3,superfamily_FN_III-like	HMMPfam_Fibrinogen_C,HMMSmart_FBG,superfamily_Fibrinogen_a/b/g_C,HMMPfam_fn3,HMMSmart_FN3,HMMPfam_EGF,HMMSmart_EGF,superfamily_FN_III-like,PatternScan_EGF_1,PatternScan_EGF_2,HMMPfam_EGF_2	-	no_errors	97	2	2.02	173	116	40.00	16	10	38.46
ITIH2	0	genome.wustl.edu	36	10	7831225	7831225	+	Silent	SNP	C	C	T			TCGA-AB-2929-03A-01W-0732-08	TCGA-AB-2929-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	3ca5c769-b07c-4a68-818d-ab2bb8141170	0aa884ea-58b7-4079-a204-be6fe7e90a24	10	7831225	7831225	C	T	SNP	ITIH2	NM_002216.2	human	genbank	54_36p	+1	validated	silent	c.2763	p.N921	1.000	HMMPfam_ITI_HC_C	HMMPfam_VWA,HMMSmart_VWA,HMMSmart_VIT,HMMPfam_ITI_HC_C,HMMPfam_VIT,superfamily_SSF53300	-	no_errors	59	4	6.35	78	61	43.57	10	11	52.38
TPH1	0	genome.wustl.edu	36	11	18001042	18001042	+	Nonsense_Mutation	SNP	C	C	A			TCGA-AB-2929-03A-01W-0732-08	TCGA-AB-2929-11A-01W-0732-08	C	C	C	A	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	3ca5c769-b07c-4a68-818d-ab2bb8141170	0aa884ea-58b7-4079-a204-be6fe7e90a24	11	18001042	18001042	C	A	SNP	TPH1	NM_004179.1	human	genbank	54_36p	-1	provisional	nonsense	c.1039	p.G347*	1.000	HMMPfam_Biopterin_H,superfamily_Aromatic aminoacid monoxygenases catalytic and oligomerization domains	HMMPfam_ACT,PatternScan_BIOPTERIN_HYDROXYL,HMMPfam_Biopterin_H,superfamily_Aromatic aminoacid monoxygenases catalytic and oligomerization domains,superfamily_ACT-like	-	no_errors	83	3	3.49	94	60	38.96	1	1	50.00
E2F8	0	genome.wustl.edu	36	11	19208937	19208937	+	Missense_Mutation	SNP	A	A	G			TCGA-AB-2929-03A-01W-0732-08	TCGA-AB-2929-11A-01W-0732-08	A	A	A	G	A	A	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	3ca5c769-b07c-4a68-818d-ab2bb8141170	0aa884ea-58b7-4079-a204-be6fe7e90a24	11	19208937	19208937	A	G	SNP	E2F8	NM_024680.2	human	genbank	54_36p	-1	validated	missense	c.1087	p.F363L	0.000	NULL	"HMMPfam_E2F_TDP,superfamily_""Winged helix"" DNA-binding domain"	-	no_errors	89	5	5.21	101	77	42.31	4	2	33.33
OR8B12	0	genome.wustl.edu	36	11	123918146	123918146	+	Silent	SNP	G	G	A			TCGA-AB-2929-03A-01W-0732-08	TCGA-AB-2929-11A-01W-0732-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	3ca5c769-b07c-4a68-818d-ab2bb8141170	0aa884ea-58b7-4079-a204-be6fe7e90a24	11	123918146	123918146	G	A	SNP	OR8B12	NM_001005195.1	human	genbank	54_36p	-1	provisional	silent	c.615	p.D205	0.006	HMMPfam_7tm_1,superfamily_Family A G protein-coupled receptor-like	HMMPfam_7tm_1,PatternScan_G_PROTEIN_RECEP_F1_1,superfamily_Family A G protein-coupled receptor-like	-	no_errors	68	0	0.00	133	38	22.09	NA	NA	NA
KRAS	0	genome.wustl.edu	36	12	25289551	25289551	+	Missense_Mutation	SNP	C	C	T	rs121913529		TCGA-AB-2929-03A-01W-0732-08	TCGA-AB-2929-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	3ca5c769-b07c-4a68-818d-ab2bb8141170	0aa884ea-58b7-4079-a204-be6fe7e90a24	12	25289551	25289551	C	T	SNP	KRAS	NM_033360.3	human	genbank	54_36p	-1	reviewed	missense	c.35	p.G12D	1.000	HMMSmart_SM00176,HMMSmart_SM00173,HMMSmart_SM00174,HMMSmart_SM00175,HMMPfam_Ras,superfamily_P-loop containing nucleoside triphosphate hydrolases	HMMSmart_SM00176,HMMSmart_SM00173,HMMSmart_SM00174,HMMSmart_SM00175,HMMPfam_Ras,superfamily_P-loop containing nucleoside triphosphate hydrolases	-	no_errors	22	2	8.00	16	37	69.81	0	18	100.00
ALDH1A3	0	genome.wustl.edu	36	15	99245387	99245387	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2929-03A-01W-0732-08	TCGA-AB-2929-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	3ca5c769-b07c-4a68-818d-ab2bb8141170	0aa884ea-58b7-4079-a204-be6fe7e90a24	15	99245387	99245387	C	T	SNP	ALDH1A3	NM_000693.2	human	genbank	54_36p	+1	reviewed	missense	c.292	p.R98W	0.960	HMMPfam_Aldedh,superfamily_Aldehyde_DH/Histidinol_DH	HMMPfam_Aldedh,PatternScan_ALDEHYDE_DEHYDR_CYS,PatternScan_ALDEHYDE_DEHYDR_GLU,superfamily_Aldehyde_DH/Histidinol_DH	-	no_errors	14	0	0.00	24	18	41.86	NA	NA	NA
CD70	0	genome.wustl.edu	36	19	6537144	6537144	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2929-03A-01W-0732-08	TCGA-AB-2929-11A-01W-0732-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	3ca5c769-b07c-4a68-818d-ab2bb8141170	0aa884ea-58b7-4079-a204-be6fe7e90a24	19	6537144	6537144	G	A	SNP	CD70	NM_001252.3	human	genbank	54_36p	-1	reviewed	missense	c.469	p.R157C	0.958	HMMPfam_TNF,HMMSmart_SM00207,superfamily_TNF-like	HMMPfam_TNF,HMMSmart_SM00207,PatternScan_TNF_1,superfamily_TNF-like	-	no_errors	83	8	8.70	151	74	32.89	11	9	45.00
PCDHGA10	0	genome.wustl.edu	36	5	140773949	140773951	+	In_Frame_Del	DEL	AGA	AGA	-			TCGA-AB-2929-03A-01W-0732-08	TCGA-AB-2929-11A-01W-0732-08	AGA	AGA	AGA	-	AGA	AGA	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	3ca5c769-b07c-4a68-818d-ab2bb8141170	0aa884ea-58b7-4079-a204-be6fe7e90a24	5	140773949	140773951	AGA	-	DEL	PCDHGA10	NM_018913.2	human	genbank	54_36p	+1	reviewed	in_frame_del	c.1023_1025	p.E342in_frame_del	0.002:0.003:0.175	HMMPfam_Cadherin,HMMSmart_SM00112,PatternScan_CADHERIN_1,superfamily_Cadherin-like	HMMPfam_Cadherin,HMMSmart_SM00112,PatternScan_CADHERIN_1,HMMPfam_Cadherin_2,superfamily_Cadherin-like	-	no_errors	0	0	0.00	0	12	27.91	0	0	0.00