Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	NormalRefReads_WU	NormalVarReads_WU	NormalVAF_WU	TumorRefReads_WU	TumorVarReads_WU	TumorVAF_WU	RNARefReads_WU	RNAVarReads_WU	RNAVAF_WU
MT-CO2	0	genome.wustl.edu	36	MT	7622	7622	+	Silent	SNP	T	T	C			TCGA-AB-2935-03A-01W-0755-09	TCGA-AB-2935-11A-01W-0755-09	T	T	T	C	T	T	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	a95d9260-b4d0-4b95-bfea-c605f940688c	d4bd29d6-e3ec-4007-82cf-10f0b87caaae	MT	7622	7622	T	C	SNP	MT-CO2	ENST00000361739	human	ensembl	54_36p	+1	known	silent	c.36	p.A12	NULL	HMMPfam_COX2_TM,superfamily_Cytochrome^^_^^c^^_^^oxidase^^_^^subunit^^_^^II-like^^_^^transmembrane^^_^^region	PatternScan_COX2,HMMPfam_COX2,superfamily_Cupredoxins,HMMPfam_COX2_TM,superfamily_Cytochrome^^_^^c^^_^^oxidase^^_^^subunit^^_^^II-like^^_^^transmembrane^^_^^region	-	no_errors	2128	3	0.14	3464	518	12.90	NA	NA	NA
ZBTB33	0	genome.wustl.edu	36	X	119271326	119271326	+	Missense_Mutation	SNP	A	A	C			TCGA-AB-2935-03A-01W-0755-09	TCGA-AB-2935-11A-01W-0755-09	A	A	A	C	A	A	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	a95d9260-b4d0-4b95-bfea-c605f940688c	d4bd29d6-e3ec-4007-82cf-10f0b87caaae	X	119271326	119271326	A	C	SNP	ZBTB33	NM_006777.3	human	genbank	54_36p	+1	validated	missense	c.28	p.T10P	1.000	superfamily_POZ domain	HMMSmart_SM00225,HMMPfam_zf-C2H2,PatternScan_ZINC_FINGER_C2H2_1,superfamily_POZ domain,HMMPfam_BTB,HMMSmart_SM00355,superfamily_C2H2 and C2HC zinc fingers	-	no_errors	122	2	1.61	47	63	57.27	1	19	95.00
GJB3	0	genome.wustl.edu	36	1	35023379	35023379	+	Missense_Mutation	SNP	C	C	G			TCGA-AB-2935-03A-01W-0755-09	TCGA-AB-2935-11A-01W-0755-09	C	C	C	G	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	a95d9260-b4d0-4b95-bfea-c605f940688c	d4bd29d6-e3ec-4007-82cf-10f0b87caaae	1	35023379	35023379	C	G	SNP	GJB3	NM_001005752.1	human	genbank	54_36p	+1	reviewed	missense	c.429	p.F143L	0.072	HMMPfam_Connexin_CCC	HMMPfam_Connexin,HMMSmart_SM00037,PatternScan_CONNEXINS_1,PatternScan_CONNEXINS_2,HMMPfam_Connexin_CCC	-	no_errors	264	2	0.75	396	148	26.81	0	1	100.00
CAMKV	0	genome.wustl.edu	36	3	49871771	49871771	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2935-03A-01W-0755-09	TCGA-AB-2935-11A-01W-0755-09	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	a95d9260-b4d0-4b95-bfea-c605f940688c	d4bd29d6-e3ec-4007-82cf-10f0b87caaae	3	49871771	49871771	C	T	SNP	CAMKV	NM_024046.3	human	genbank	54_36p	-1	validated	missense	c.1490	p.R497K	0.693	NULL	HMMSmart_SM00219,HMMSmart_SM00220,superfamily_Protein kinase-like (PK-like),HMMPfam_Pkinase	-	no_errors	82	0	0.00	137	58	29.29	NA	NA	NA
LOC441013	0	genome.wustl.edu	36	4	43107115	43107115	+	RNA	SNP	G	G	A			TCGA-AB-2935-03A-01W-0755-09	TCGA-AB-2935-11A-01W-0755-09	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	a95d9260-b4d0-4b95-bfea-c605f940688c	d4bd29d6-e3ec-4007-82cf-10f0b87caaae	4	43107115	43107115	G	A	SNP	LOC441013	XR_016299.2	human	genbank	54_36p	-1	model	rna	NULL	NULL	1.000	-	-	-	pseudogene	113	1	0.88	209	79	27.34	NA	NA	NA
ALOX5	0	genome.wustl.edu	36	10	45258945	45258945	+	Silent	SNP	C	C	T			TCGA-AB-2935-03A-01W-0755-09	TCGA-AB-2935-11A-01W-0755-09	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	a95d9260-b4d0-4b95-bfea-c605f940688c	d4bd29d6-e3ec-4007-82cf-10f0b87caaae	10	45258945	45258945	C	T	SNP	ALOX5	NM_000698.2	human	genbank	54_36p	+1	reviewed	silent	c.1527	p.F509	0.944	HMMPfam_Lipoxygenase,superfamily_Lipoxygenase	HMMPfam_PLAT,HMMSmart_LH2,superfamily_Lipase_LipOase,HMMPfam_Lipoxygenase,PatternScan_LIPOXYGENASE_2,PatternScan_LIPOXYGENASE_1,superfamily_Lipoxygenase	-	no_errors	36	0	0.00	124	45	26.32	30	15	32.61
LOC387703	0	genome.wustl.edu	36	10	94956679	94956679	+	RNA	SNP	G	G	A			TCGA-AB-2935-03A-01W-0755-09	TCGA-AB-2935-11A-01W-0755-09	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	a95d9260-b4d0-4b95-bfea-c605f940688c	d4bd29d6-e3ec-4007-82cf-10f0b87caaae	10	94956679	94956679	G	A	SNP	LOC387703	XR_016730.2	human	genbank	54_36p	-1	model	rna	NULL	NULL	0.943	-	-	-	pseudogene	201	3	1.46	410	277	39.86	NA	NA	NA
ANO3	0	genome.wustl.edu	36	11	26620060	26620060	+	Missense_Mutation	SNP	G	G	C			TCGA-AB-2935-03A-01W-0755-09	TCGA-AB-2935-11A-01W-0755-09	G	G	G	C	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	a95d9260-b4d0-4b95-bfea-c605f940688c	d4bd29d6-e3ec-4007-82cf-10f0b87caaae	11	26620060	26620060	G	C	SNP	ANO3	NM_031418.2	human	genbank	54_36p	+1	validated	missense	c.2183	p.G728A	0.983	HMMPfam_DUF590	HMMPfam_DUF590	-	no_errors	283	0	0.00	364	144	28.24	NA	NA	NA
FREM2	0	genome.wustl.edu	36	13	38350970	38350970	+	Silent	SNP	C	C	T			TCGA-AB-2935-03A-01W-0755-09	TCGA-AB-2935-11A-01W-0755-09	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	a95d9260-b4d0-4b95-bfea-c605f940688c	d4bd29d6-e3ec-4007-82cf-10f0b87caaae	13	38350970	38350970	C	T	SNP	FREM2	NM_207361.4	human	genbank	54_36p	+1	reviewed	silent	c.8862	p.D2954	1.000	NULL	HMMPfam_Calx-beta,HMMSmart_SM00237	-	no_errors	184	1	0.54	208	75	26.41	NA	NA	NA
HERC2	0	genome.wustl.edu	36	15	26062848	26062848	+	Missense_Mutation	SNP	G	G	T			TCGA-AB-2935-03A-01W-0755-09	TCGA-AB-2935-11A-01W-0755-09	G	G	G	T	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	a95d9260-b4d0-4b95-bfea-c605f940688c	d4bd29d6-e3ec-4007-82cf-10f0b87caaae	15	26062848	26062848	G	T	SNP	HERC2	NM_004667.4	human	genbank	54_36p	-1	validated	missense	c.11269	p.L3757M	0.998	NULL	HMMPfam_RCC1,PatternScan_RCC1_2,HMMPfam_ZZ,HMMSmart_SM00291,PatternScan_ZF_ZZ_1,HMMPfam_HECT,HMMSmart_SM00119,superfamily_Hect E3 ligase catalytic domain,HMMPfam_Cyt-b5,superfamily_Cytochrome b5-like heme/steroid binding domain,HMMSmart_SM00706,superfamily_Galactose-binding domain-like,superfamily_RCC1/BLIP-II,HMMPfam_MIB_HERC2,PatternScan_PROTEIN_KINASE_ATP	-	no_errors	109	0	0.00	185	71	27.73	24	14	36.84
TP53	0	genome.wustl.edu	36	17	7518263	7518263	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2935-03A-01W-0755-09	TCGA-AB-2935-11A-01W-0755-09	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	a95d9260-b4d0-4b95-bfea-c605f940688c	d4bd29d6-e3ec-4007-82cf-10f0b87caaae	17	7518263	7518263	C	T	SNP	TP53	NM_000546.4	human	genbank	54_36p	-1	reviewed	missense	c.743	p.R248Q	1.000	PatternScan_P53,superfamily_p53-like transcription factors,HMMPfam_P53	PatternScan_P53,superfamily_p53-like transcription factors,HMMPfam_P53_tetramer,superfamily_p53 tetramerization domain,HMMPfam_P53,HMMPfam_P53_TAD	-	no_errors	254	5	1.93	321	283	46.47	14	79	84.95
ZNF229	0	genome.wustl.edu	36	19	49625375	49625375	+	Missense_Mutation	SNP	G	G	C			TCGA-AB-2935-03A-01W-0755-09	TCGA-AB-2935-11A-01W-0755-09	G	G	G	C	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	a95d9260-b4d0-4b95-bfea-c605f940688c	d4bd29d6-e3ec-4007-82cf-10f0b87caaae	19	49625375	49625375	G	C	SNP	ZNF229	NM_014518.2	human	genbank	54_36p	-1	validated	missense	c.1421	p.S474C	0.205	HMMPfam_zf-C2H2,PatternScan_ZINC_FINGER_C2H2_1,HMMSmart_SM00355,superfamily_C2H2 and C2HC zinc fingers	HMMPfam_KRAB,HMMSmart_SM00349,superfamily_KRAB domain (Kruppel-associated box Pfam 01352),HMMPfam_zf-C2H2,PatternScan_ZINC_FINGER_C2H2_1,HMMSmart_SM00355,superfamily_C2H2 and C2HC zinc fingers	-	no_errors	206	0	0.00	276	135	32.61	4	2	33.33
RIN2	0	genome.wustl.edu	36	20	19904215	19904215	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2935-03A-01W-0755-09	TCGA-AB-2935-11A-01W-0755-09	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	a95d9260-b4d0-4b95-bfea-c605f940688c	d4bd29d6-e3ec-4007-82cf-10f0b87caaae	20	19904215	19904215	C	T	SNP	RIN2	NM_018993.2	human	genbank	54_36p	+1	reviewed	missense	c.1546	p.R516C	0.801	NULL	HMMPfam_RA,HMMSmart_SM00314,HMMPfam_VPS9,HMMSmart_SM00167,superfamily_VPS9 domain (Pfam 02204),superfamily_SH2 domain	-	no_errors	67	0	0.00	198	78	28.26	6	6	50.00