Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	NormalRefReads_WU	NormalVarReads_WU	NormalVAF_WU	TumorRefReads_WU	TumorVarReads_WU	TumorVAF_WU	RNARefReads_WU	RNAVarReads_WU	RNAVAF_WU
MT-ND4	0	genome.wustl.edu	36	MT	11462	11462	+	Silent	SNP	A	A	G			TCGA-AB-2937-03A-01W-0732-08	TCGA-AB-2937-11A-01W-0732-08	A	A	A	G	A	A	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	d17268d0-1552-418e-9118-b9b313b54d37	d44fcf31-c277-461d-bdab-b952d2e14bb0	MT	11462	11462	A	G	SNP	MT-ND4	ENST00000361381	human	ensembl	54_36p	+1	known	silent	c.702	p.V234	NULL	HMMPfam_Oxidored_q1	HMMPfam_Oxidored_q5_N,HMMPfam_Oxidored_q1	-	no_stop_codon:bad_bp_length_for_coding_region	1213	16	1.30	2519	360	12.47	NA	NA	NA
ENSG00000216522	0	genome.wustl.edu	36	NT_113923	88049	88050	+	Splice_Site	SNP	G	G	A			TCGA-AB-2937-03A-01W-0732-08	TCGA-AB-2937-11A-01W-0732-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	d17268d0-1552-418e-9118-b9b313b54d37	d44fcf31-c277-461d-bdab-b952d2e14bb0	NT_113923	88049	88050	G	A	SNP	ENSG00000216522	ENST00000402757	human	ensembl	54_36p	-1	known	splice_site	c.733-1	e6-1	NULL	-	-	-	no_errors	73	2	2.67	21	18	46.15	NA	NA	NA
KIT	0	genome.wustl.edu	36	4	55294078	55294078	+	Missense_Mutation	SNP	A	A	T	rs121913507		TCGA-AB-2937-03A-01W-0732-08	TCGA-AB-2937-11A-01W-0732-08	A	A	A	T	A	A	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	d17268d0-1552-418e-9118-b9b313b54d37	d44fcf31-c277-461d-bdab-b952d2e14bb0	4	55294078	55294078	A	T	SNP	KIT	NM_000222.2	human	genbank	54_36p	+1	reviewed	missense	c.2447	p.D816V	1.000	HMMPfam_Pkinase_Tyr,HMMSmart_TyrKc,superfamily_Kinase_like	HMMPfam_Pkinase_Tyr,HMMSmart_TyrKc,PatternScan_RECEPTOR_TYR_KIN_III,HMMSmart_IGc2,HMMSmart_IG,PatternScan_PROTEIN_KINASE_TYR,superfamily_Kinase_like,HMMPfam_ig,PatternScan_PROTEIN_KINASE_ATP,superfamily_SSF48726	-	no_errors	54	2	3.57	35	28	44.44	44	49	52.69
C2	0	genome.wustl.edu	36	6	32009522	32009522	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2937-03A-01W-0732-08	TCGA-AB-2937-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	d17268d0-1552-418e-9118-b9b313b54d37	d44fcf31-c277-461d-bdab-b952d2e14bb0	6	32009522	32009522	C	T	SNP	C2	NM_000063.4	human	genbank	54_36p	+1	reviewed	missense	c.599	p.T200M	0.933	HMMPfam_Sushi,HMMSmart_SM00032,superfamily_Complement control module/SCR domain	HMMPfam_Sushi,HMMSmart_SM00032,HMMPfam_Trypsin,HMMSmart_SM00020,HMMPfam_VWA,HMMSmart_SM00327,superfamily_Trypsin-like serine proteases,superfamily_Complement control module/SCR domain,PatternScan_TRYPSIN_HIS,PatternScan_TRYPSIN_SER,superfamily_vWA-like	-	no_errors	99	2	1.98	15	22	59.46	5	0	0.00
GPR115	0	genome.wustl.edu	36	6	47789760	47789760	+	Nonsense_Mutation	SNP	C	C	T			TCGA-AB-2937-03A-01W-0732-08	TCGA-AB-2937-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	d17268d0-1552-418e-9118-b9b313b54d37	d44fcf31-c277-461d-bdab-b952d2e14bb0	6	47789760	47789760	C	T	SNP	GPR115	NM_153838.3	human	genbank	54_36p	+1	validated	nonsense	c.820	p.Q274*	0.042	NULL	HMMPfam_7tm_2	-	no_errors	156	7	4.29	36	24	40.00	NA	NA	NA
WBSCR17	0	genome.wustl.edu	36	7	70768465	70768465	+	Nonsense_Mutation	SNP	G	G	A			TCGA-AB-2937-03A-01W-0732-08	TCGA-AB-2937-11A-01W-0732-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	d17268d0-1552-418e-9118-b9b313b54d37	d44fcf31-c277-461d-bdab-b952d2e14bb0	7	70768465	70768465	G	A	SNP	WBSCR17	NM_022479.1	human	genbank	54_36p	+1	reviewed	nonsense	c.1214	p.W405*	1.000	superfamily_Nucleotide-diphospho-sugar transferases	HMMPfam_Ricin_B_lectin,HMMSmart_SM00458,HMMPfam_Glycos_transf_2,superfamily_Ricin B-like lectins,superfamily_Nucleotide-diphospho-sugar transferases	-	no_errors	259	9	3.36	49	36	42.35	NA	NA	NA
GSTK1	0	genome.wustl.edu	36	7	142670736	142670736	+	Missense_Mutation	SNP	C	C	A			TCGA-AB-2937-03A-01W-0732-08	TCGA-AB-2937-11A-01W-0732-08	C	C	C	A	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	d17268d0-1552-418e-9118-b9b313b54d37	d44fcf31-c277-461d-bdab-b952d2e14bb0	7	142670736	142670736	C	A	SNP	GSTK1	NM_015917.1	human	genbank	54_36p	+1	reviewed	missense	c.8	p.P3H	0.294	superfamily_Thioredoxin-like	HMMPfam_DSBA,superfamily_Thioredoxin-like	-	no_errors	103	2	1.90	24	21	46.67	156	103	39.77
ZFHX4	0	genome.wustl.edu	36	8	77926663	77926663	+	Missense_Mutation	SNP	G	G	C			TCGA-AB-2937-03A-01W-0732-08	TCGA-AB-2937-11A-01W-0732-08	G	G	G	C	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	d17268d0-1552-418e-9118-b9b313b54d37	d44fcf31-c277-461d-bdab-b952d2e14bb0	8	77926663	77926663	G	C	SNP	ZFHX4	NM_024721.3	human	genbank	54_36p	+1	validated	missense	c.4816	p.D1606H	0.990	NULL	HMMPfam_Homeobox,HMMSmart_SM00389,HMMSmart_SM00451,HMMPfam_zf-C2H2,PatternScan_ZINC_FINGER_C2H2_1,superfamily_Homeodomain-like,HMMSmart_SM00355,PatternScan_HOMEOBOX_1,PatternScan_SOMATOTROPIN_2,superfamily_C2H2 and C2HC zinc fingers	-	no_errors	290	5	1.69	73	51	41.13	NA	NA	NA
TMTC4	0	genome.wustl.edu	36	13	100075849	100075849	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2937-03A-01W-0732-08	TCGA-AB-2937-11A-01W-0732-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	d17268d0-1552-418e-9118-b9b313b54d37	d44fcf31-c277-461d-bdab-b952d2e14bb0	13	100075849	100075849	G	A	SNP	TMTC4	NM_032813.1	human	genbank	54_36p	-1	validated	missense	c.1777	p.R593W	1.000	HMMPfam_TPR_1,HMMSmart_SM00028,superfamily_TPR-like	HMMPfam_TPR_1,HMMPfam_TPR_2,HMMPfam_DUF1736,HMMSmart_SM00028,superfamily_TPR-like	-	no_errors	282	17	5.69	65	42	39.25	9	9	50.00
DNAH9	0	genome.wustl.edu	36	17	11495324	11495324	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2937-03A-01W-0732-08	TCGA-AB-2937-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	d17268d0-1552-418e-9118-b9b313b54d37	d44fcf31-c277-461d-bdab-b952d2e14bb0	17	11495324	11495324	C	T	SNP	DNAH9	NM_001372.3	human	genbank	54_36p	+1	reviewed	missense	c.2311	p.R771C	0.002	HMMPfam_DHC_N1	HMMSmart_SM00382,HMMPfam_Dynein_heavy,PatternScan_CPSASE_2,HMMPfam_AAA_5,HMMPfam_DHC_N1,HMMPfam_DHC_N2,superfamily_Spectrin repeat,superfamily_P-loop containing nucleoside triphosphate hydrolases	-	no_errors	148	4	2.63	31	29	48.33	NA	NA	NA
RNF213	0	genome.wustl.edu	36	17	75936028	75936028	+	Missense_Mutation	SNP	G	G	C			TCGA-AB-2937-03A-01W-0732-08	TCGA-AB-2937-11A-01W-0732-08	G	G	G	C	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	d17268d0-1552-418e-9118-b9b313b54d37	d44fcf31-c277-461d-bdab-b952d2e14bb0	17	75936028	75936028	G	C	SNP	RNF213	NM_020914.3	human	genbank	54_36p	+1	validated	missense	c.3517	p.V1173L	1.000	NULL	HMMSmart_SM00184,HMMSmart_SM00382,HMMPfam_zf-C3HC4,superfamily_P-loop containing nucleoside triphosphate hydrolases,superfamily_RING/U-box	-	no_errors	65	2	2.99	22	10	31.25	40	31	43.66
TET2	0	genome.wustl.edu	36	4	106374923	106374923	+	Frame_Shift_Del	DEL	C	C	-			TCGA-AB-2937-03A-01W-0732-08	TCGA-AB-2937-11A-01W-0732-08	C	C	C	-	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	d17268d0-1552-418e-9118-b9b313b54d37	d44fcf31-c277-461d-bdab-b952d2e14bb0	4	106374923	106374923	C	-	DEL	TET2	NM_017628.1	human	genbank	54_36p	+1	validated	frame_shift_del	c.375	p.F125fs	0.600	NULL	NULL	-	no_errors	0	0	0.00	1	3	60.00	0	12	75.00
HNRNPK	0	genome.wustl.edu	36	9	85781728	85781729	+	Splice_Site	INS	-	-	T			TCGA-AB-2937-03A-01W-0732-08	TCGA-AB-2937-11A-01W-0732-08	-	-	-	T	-	-	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	d17268d0-1552-418e-9118-b9b313b54d37	d44fcf31-c277-461d-bdab-b952d2e14bb0	9	85781728	85781729	-	T	INS	HNRNPK	NM_002140.3	human	genbank	54_36p	-1	reviewed	splice_site_ins	c.213+1_213+1	e3+1	1.000:1.000	-	-	-	no_errors	55	0	0.00	36	20	35.71	15	33	68.75
HNRNPK	0	genome.wustl.edu	36	9	85781729	85781730	+	Frame_Shift_Ins	INS	-	-	TA			TCGA-AB-2937-03A-01W-0732-08	TCGA-AB-2937-11A-01W-0732-08	-	-	-	TA	-	-	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	d17268d0-1552-418e-9118-b9b313b54d37	d44fcf31-c277-461d-bdab-b952d2e14bb0	9	85781729	85781730	-	TA	INS	HNRNPK	NM_002140.3	human	genbank	54_36p	-1	reviewed	frame_shift_ins	c.214_213	p.N72fs	1.000:1.000	HMMSmart_SM00322,HMMPfam_KH_1,superfamily_Eukaryotic type KH-domain (KH-domain type I)	HMMSmart_SM00322,HMMPfam_ROKNT,HMMPfam_KH_1,superfamily_Eukaryotic type KH-domain (KH-domain type I)	-	no_errors	56	0	0.00	36	20	35.71	52	0	0.00