Hugo_Symbol Entrez_Gene_Id Center NCBI_Build Chromosome Start_Position End_Position Strand Variant_Classification Variant_Type Reference_Allele Tumor_Seq_Allele1 Tumor_Seq_Allele2 dbSNP_RS dbSNP_Val_Status Tumor_Sample_Barcode Matched_Norm_Sample_Barcode Match_Norm_Seq_Allele1 Match_Norm_Seq_Allele2 Tumor_Validation_Allele1 Tumor_Validation_Allele2 Match_Norm_Validation_Allele1 Match_Norm_Validation_Allele2 Verification_Status Validation_Status Mutation_Status Sequencing_Phase Sequence_Source Validation_Method Score BAM_File Sequencer Tumor_Sample_UUID Matched_Norm_Sample_UUID chromosome_name start stop reference variant type gene_name transcript_name transcript_species transcript_source transcript_version strand transcript_status trv_type c_position amino_acid_change ucsc_cons domain all_domains deletion_substructures transcript_error NormalRefReads_WU NormalVarReads_WU NormalVAF_WU TumorRefReads_WU TumorVarReads_WU TumorVAF_WU RNARefReads_WU RNAVarReads_WU RNAVAF_WU MLL3 0 genome.wustl.edu 36 7 151505094 151505094 + Nonsense_Mutation SNP C C A TCGA-AB-2940-03A-01W-0733-08 TCGA-AB-2940-11A-01W-0732-08 C C C A C C Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 6d2b23e2-12c0-4f19-a8f4-defe50ffeeb5 286c5568-d97b-4af0-9c61-47d91dd7ec12 7 151505094 151505094 C A SNP MLL3 NM_170606.2 human genbank 54_36p -1 reviewed nonsense c.8377 p.E2793* 0.943 NULL PatternScan_HMGI_Y,HMMPfam_HMG_box,HMMSmart_SM00398,HMMPfam_SET,HMMSmart_SM00317,HMMSmart_SM00184,HMMSmart_SM00249,HMMSmart_SM00508,HMMPfam_FYRN,HMMPfam_FYRC,superfamily_FYVE/PHD zinc finger,HMMPfam_AT_hook,HMMSmart_SM00542,HMMSmart_SM00541,PatternScan_ZF_PHD_1,HMMPfam_PHD,PatternScan_ATPASE_ALPHA_BETA,superfamily_SET domain - no_errors 226 7 2.99 96 21 17.95 44 8 15.38 NEURL4 0 genome.wustl.edu 36 17 7169461 7169461 + Silent SNP C C T TCGA-AB-2940-03A-01W-0733-08 TCGA-AB-2940-11A-01W-0732-08 C C C T C C Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 6d2b23e2-12c0-4f19-a8f4-defe50ffeeb5 286c5568-d97b-4af0-9c61-47d91dd7ec12 17 7169461 7169461 C T SNP NEURL4 NM_032442.1 human genbank 54_36p -1 validated silent c.1422 p.G474 1.000 NULL HMMPfam_Neuralized,HMMSmart_SM00588 - no_errors 57 6 9.52 26 8 23.53 32 6 15.79 LOC729135 0 genome.wustl.edu 36 1 147939842 147939843 + RNA INS - - C TCGA-AB-2940-03A-01W-0733-08 TCGA-AB-2940-11A-01W-0732-08 - - - C - - Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 6d2b23e2-12c0-4f19-a8f4-defe50ffeeb5 286c5568-d97b-4af0-9c61-47d91dd7ec12 1 147939842 147939843 - C INS LOC729135 XR_039107.1 human genbank 54_36p -1 model rna NULL NULL 0.009:0.013 - - - pseudogene 8 0 0.00 29 8 21.62 22 0 0.00 CEBPA 0 genome.wustl.edu 36 19 38484235 38484236 + In_Frame_Ins INS - - CCA TCGA-AB-2940-03A-01W-0733-08 TCGA-AB-2940-11A-01W-0732-08 - - - CCA - - Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 6d2b23e2-12c0-4f19-a8f4-defe50ffeeb5 286c5568-d97b-4af0-9c61-47d91dd7ec12 19 38484235 38484236 - CCA INS CEBPA NM_004364.3 human genbank 54_36p -1 reviewed in_frame_ins c.926_925 p.309in_frame_insV 1.000:1.000 HMMSmart_BRLZ,HMMPfam_bZIP_2 HMMSmart_BRLZ,PatternScan_BZIP_BASIC,HMMPfam_bZIP_2 - no_errors 1 0 0.00 11 8 42.11 143 114 44.36 CEBPA 0 genome.wustl.edu 36 19 38485093 38485093 + Frame_Shift_Del DEL G G - rs137852728 TCGA-AB-2940-03A-01W-0733-08 TCGA-AB-2940-11A-01W-0732-08 G G G - G G Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 6d2b23e2-12c0-4f19-a8f4-defe50ffeeb5 286c5568-d97b-4af0-9c61-47d91dd7ec12 19 38485093 38485093 G - DEL CEBPA NM_004364.3 human genbank 54_36p -1 reviewed frame_shift_del c.68 p.P23fs 0.998 NULL HMMSmart_BRLZ,PatternScan_BZIP_BASIC,HMMPfam_bZIP_2 - no_errors 0 0 0.00 0 0 0.00 64 31 32.29