Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	NormalRefReads_WU	NormalVarReads_WU	NormalVAF_WU	TumorRefReads_WU	TumorVarReads_WU	TumorVAF_WU	RNARefReads_WU	RNAVarReads_WU	RNAVAF_WU
FAM5C	0	genome.wustl.edu	36	1	188334613	188334613	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2965-03A-01D-0739-09	TCGA-AB-2965-11A-01D-0739-09	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	3467d556-ea36-46aa-b48f-29896f5b56f3	882146d8-0b40-490b-b405-7ba28bf8aaa0	1	188334613	188334613	C	T	SNP	FAM5C	NM_199051.1	human	genbank	54_36p	-1	provisional	missense	c.1459	p.G487S	1.000	NULL	HMMPfam_MACPF,HMMSmart_SM00457	-	no_errors	382	58	13.18	308	275	47.09	NA	NA	NA
DNMT3A	0	genome.wustl.edu	36	2	25310746	25310746	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2965-03A-01D-0739-09	TCGA-AB-2965-11A-01D-0739-09	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	3467d556-ea36-46aa-b48f-29896f5b56f3	882146d8-0b40-490b-b405-7ba28bf8aaa0	2	25310746	25310746	C	T	SNP	DNMT3A	NM_022552.3	human	genbank	54_36p	-1	reviewed	missense	c.2645	p.R882H	1.000	superfamily_S-adenosyl-L-methionine-dependent methyltransferases	HMMPfam_PWWP,HMMSmart_SM00293,HMMPfam_DNA_methylase,superfamily_FYVE/PHD zinc finger,PatternScan_C5_MTASE_1,superfamily_S-adenosyl-L-methionine-dependent methyltransferases,superfamily_Tudor/PWWP/MBT	-	no_errors	21	4	16.00	12	10	45.45	16	15	48.39
LOC730032	0	genome.wustl.edu	36	2	131391188	131391188	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2965-03A-01D-0739-09	TCGA-AB-2965-11A-01D-0739-09	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	3467d556-ea36-46aa-b48f-29896f5b56f3	882146d8-0b40-490b-b405-7ba28bf8aaa0	2	131391188	131391188	G	A	SNP	LOC730032	XM_001132160.2	human	genbank	54_36p	+1	model	missense	c.3199	p.A1067T	0.000	NULL	NULL	-	no_errors	93	14	13.08	99	110	52.63	NA	NA	NA
VIPR1	0	genome.wustl.edu	36	3	42530257	42530257	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2965-03A-01D-0739-09	TCGA-AB-2965-11A-01D-0739-09	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	3467d556-ea36-46aa-b48f-29896f5b56f3	882146d8-0b40-490b-b405-7ba28bf8aaa0	3	42530257	42530257	G	A	SNP	VIPR1	NM_004624.3	human	genbank	54_36p	+1	validated	missense	c.91	p.A31T	0.000	superfamily_Hormone receptor domain (HRM Pfam 02793)	HMMPfam_7tm_2,HMMPfam_HRM,HMMSmart_SM00008,PatternScan_G_PROTEIN_RECEP_F2_1,PatternScan_G_PROTEIN_RECEP_F2_2,superfamily_Hormone receptor domain (HRM Pfam 02793),superfamily_Family A G protein-coupled receptor-like	-	no_errors	342	48	12.24	87	115	56.93	NA	NA	NA
HK1	0	genome.wustl.edu	36	10	70828539	70828539	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2965-03A-01D-0739-09	TCGA-AB-2965-11A-01D-0739-09	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	3467d556-ea36-46aa-b48f-29896f5b56f3	882146d8-0b40-490b-b405-7ba28bf8aaa0	10	70828539	70828539	G	A	SNP	HK1	NM_033497.2	human	genbank	54_36p	+1	reviewed	missense	c.2570	p.R857H	0.888	HMMPfam_Hexokinase_2,superfamily_SSF53067	HMMPfam_Hexokinase_1,HMMPfam_Hexokinase_2,PatternScan_HEXOKINASES,superfamily_SSF53067	-	no_errors	557	119	17.47	190	183	48.93	32	27	45.76
RASSF7	0	genome.wustl.edu	36	11	552159	552159	+	Missense_Mutation	SNP	G	G	T			TCGA-AB-2965-03A-01D-0739-09	TCGA-AB-2965-11A-01D-0739-09	G	G	G	T	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	3467d556-ea36-46aa-b48f-29896f5b56f3	882146d8-0b40-490b-b405-7ba28bf8aaa0	11	552159	552159	G	T	SNP	RASSF7	NM_003475.1	human	genbank	54_36p	+1	validated	missense	c.205	p.A69S	0.996	HMMPfam_RA,HMMSmart_SM00314	HMMPfam_RA,HMMSmart_SM00314	-	no_errors	59	6	9.23	28	20	41.67	3	5	62.50
EFTUD1	0	genome.wustl.edu	36	15	80317742	80317742	+	Missense_Mutation	SNP	T	T	C			TCGA-AB-2965-03A-01D-0739-09	TCGA-AB-2965-11A-01D-0739-09	T	T	T	C	T	T	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	3467d556-ea36-46aa-b48f-29896f5b56f3	882146d8-0b40-490b-b405-7ba28bf8aaa0	15	80317742	80317742	T	C	SNP	EFTUD1	NM_024580.2	human	genbank	54_36p	-1	validated	missense	c.692	p.N231S	0.997	HMMPfam_GTP_EFTU,superfamily_P-loop containing nucleoside triphosphate hydrolases	HMMPfam_EFG_C,HMMPfam_GTP_EFTU,HMMPfam_EFG_IV,superfamily_Translation proteins,superfamily_EF-G C-terminal domain-like,superfamily_Ribosomal protein S5 domain 2-like,superfamily_P-loop containing nucleoside triphosphate hydrolases	-	no_errors	376	59	13.56	191	197	50.77	8	11	57.89
ZNF689	0	genome.wustl.edu	36	16	30524020	30524020	+	Missense_Mutation	SNP	G	G	C			TCGA-AB-2965-03A-01D-0739-09	TCGA-AB-2965-11A-01D-0739-09	G	G	G	C	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	3467d556-ea36-46aa-b48f-29896f5b56f3	882146d8-0b40-490b-b405-7ba28bf8aaa0	16	30524020	30524020	G	C	SNP	ZNF689	NM_138447.1	human	genbank	54_36p	-1	provisional	missense	c.569	p.S190C	0.705	HMMPfam_zf-C2H2,PatternScan_ZINC_FINGER_C2H2_1,HMMSmart_ZnF_C2H2,superfamily_SSF57667	HMMPfam_KRAB,HMMSmart_KRAB,superfamily_Krueppel-associated_box,HMMPfam_zf-C2H2,PatternScan_ZINC_FINGER_C2H2_1,HMMSmart_ZnF_C2H2,superfamily_SSF57667	-	no_errors	386	61	13.62	126	96	43.24	2	6	75.00
TET2	0	genome.wustl.edu	36	4	106400368	106400368	+	Frame_Shift_Del	DEL	C	C	-			TCGA-AB-2965-03A-01D-0739-09	TCGA-AB-2965-11A-01D-0739-09	C	C	C	-	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	3467d556-ea36-46aa-b48f-29896f5b56f3	882146d8-0b40-490b-b405-7ba28bf8aaa0	4	106400368	106400368	C	-	DEL	TET2	ENST00000265149	human	ensembl	54_36p	+1	known	frame_shift_del	c.353	p.P118fs	1.000	NULL	NULL	-	no_start_codon	213	0	0.00	202	0	0.00	11	0	0.00
NPM1	0	genome.wustl.edu	36	5	170770152	170770153	+	Frame_Shift_Ins	INS	-	-	TCTG			TCGA-AB-2965-03A-01D-0739-09	TCGA-AB-2965-11A-01D-0739-09	-	-	-	TCTG	-	-	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	3467d556-ea36-46aa-b48f-29896f5b56f3	882146d8-0b40-490b-b405-7ba28bf8aaa0	5	170770152	170770153	-	TCTG	INS	NPM1	NM_002520.1	human	genbank	54_36p	+1	validated	frame_shift_ins	c.863_864	p.W288fs	1.000:1.000	NULL	HMMPfam_Nucleoplasmin,superfamily_Nucleoplasmin-like core domain	-	no_errors	NA	NA	NA	NA	NA	NA	NA	NA	NA
FLT3	0	genome.wustl.edu	36	13	27506338	27506339	+	In_Frame_Ins	INS	-	-	TTCTCTGAAATCAACGTAGAAGTACTCATTATCTGAGGAGCCGGTCACCTGTACCATCTGTAGCTGGCTTTT			TCGA-AB-2965-03A-01D-0739-09	TCGA-AB-2965-11A-01D-0739-09	-	-	-	TTCTCTGAAATCAACGTAGAAGTACTCATTATCTGAGGAGCCGGTCACCTGTACCATCTGTAGCTGGCTTTT	-	-	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	3467d556-ea36-46aa-b48f-29896f5b56f3	882146d8-0b40-490b-b405-7ba28bf8aaa0	13	27506338	27506339	-	TTCTCTGAAATCAACGTAGAAGTACTCATTATCTGAGGAGCCGGTCACCTGTACCATCTGTAGCTGGCTTTT	INS	FLT3	NM_004119.2	human	genbank	54_36p	-1	reviewed	in_frame_ins	c.1718_1717	p.574in_frame_insKPATDGTGDRLLR**VLLR*FQRK	1.000:1.000	superfamily_Kinase_like	HMMPfam_Pkinase_Tyr,HMMSmart_TyrKc,PatternScan_RECEPTOR_TYR_KIN_III,PatternScan_PROTEIN_KINASE_TYR,superfamily_Kinase_like,HMMPfam_ig,PatternScan_PROTEIN_KINASE_ATP,superfamily_SSF48726	-	no_errors	NA	NA	NA	NA	NA	NA	NA	NA	NA