Hugo_Symbol Entrez_Gene_Id Center NCBI_Build Chromosome Start_Position End_Position Strand Variant_Classification Variant_Type Reference_Allele Tumor_Seq_Allele1 Tumor_Seq_Allele2 dbSNP_RS dbSNP_Val_Status Tumor_Sample_Barcode Matched_Norm_Sample_Barcode Match_Norm_Seq_Allele1 Match_Norm_Seq_Allele2 Tumor_Validation_Allele1 Tumor_Validation_Allele2 Match_Norm_Validation_Allele1 Match_Norm_Validation_Allele2 Verification_Status Validation_Status Mutation_Status Sequencing_Phase Sequence_Source Validation_Method Score BAM_File Sequencer Tumor_Sample_UUID Matched_Norm_Sample_UUID chromosome_name start stop reference variant type gene_name transcript_name transcript_species transcript_source transcript_version strand transcript_status trv_type c_position amino_acid_change ucsc_cons domain all_domains deletion_substructures transcript_error NormalRefReads_WU NormalVarReads_WU NormalVAF_WU TumorRefReads_WU TumorVarReads_WU TumorVAF_WU RNARefReads_WU RNAVarReads_WU RNAVAF_WU DNMT3A 0 genome.wustl.edu 36 2 25310747 25310747 + Missense_Mutation SNP G G A TCGA-AB-2981-03A-01D-0739-09 TCGA-AB-2981-11A-01D-0739-09 G G G A G G Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 7212ba7b-f637-4f9f-b616-94109bfb8898 25cb572c-99a3-4fe6-8e7f-87ed37ab2d17 2 25310747 25310747 G A SNP DNMT3A NM_022552.3 human genbank 54_36p -1 reviewed missense c.2644 p.R882C 1.000 superfamily_S-adenosyl-L-methionine-dependent methyltransferases HMMPfam_PWWP,HMMSmart_SM00293,HMMPfam_DNA_methylase,superfamily_FYVE/PHD zinc finger,PatternScan_C5_MTASE_1,superfamily_S-adenosyl-L-methionine-dependent methyltransferases,superfamily_Tudor/PWWP/MBT - no_errors 731 185 20.07 257 263 50.48 10 11 52.38 BBS7 0 genome.wustl.edu 36 4 123010916 123010916 + Missense_Mutation SNP C C A TCGA-AB-2981-03A-01D-0739-09 TCGA-AB-2981-11A-01D-0739-09 C C C A C C Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 7212ba7b-f637-4f9f-b616-94109bfb8898 25cb572c-99a3-4fe6-8e7f-87ed37ab2d17 4 123010916 123010916 C A SNP BBS7 NM_176824.2 human genbank 54_36p -1 reviewed missense c.3 p.M1I 1.000 NULL NULL - no_errors 677 126 15.54 297 269 47.44 7 6 46.15 ZDHHC11 0 genome.wustl.edu 36 5 903655 903655 + Silent SNP C C T TCGA-AB-2981-03A-01D-0739-09 TCGA-AB-2981-11A-01D-0739-09 C C C T C C Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 7212ba7b-f637-4f9f-b616-94109bfb8898 25cb572c-99a3-4fe6-8e7f-87ed37ab2d17 5 903655 903655 C T SNP ZDHHC11 NM_024786.2 human genbank 54_36p -1 validated silent c.63 p.K21 0.002 NULL HMMPfam_zf-DHHC - no_errors 134 28 17.07 92 101 52.33 NA NA NA NEMF 0 genome.wustl.edu 36 14 49332385 49332385 + Silent SNP A A G TCGA-AB-2981-03A-01D-0739-09 TCGA-AB-2981-11A-01D-0739-09 A A A G A A Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 7212ba7b-f637-4f9f-b616-94109bfb8898 25cb572c-99a3-4fe6-8e7f-87ed37ab2d17 14 49332385 49332385 A G SNP SDCCAG1 NM_004713.3 human genbank 54_36p -1 validated silent c.2493 p.S831 0.789 NULL HMMPfam_DUF814,HMMPfam_FbpA - no_errors 394 59 12.94 136 103 43.10 37 33 47.14 LOC100128562 0 genome.wustl.edu 36 15 73623618 73623618 + Silent SNP C C T TCGA-AB-2981-03A-01D-0739-09 TCGA-AB-2981-11A-01D-0739-09 C C C T C C Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 7212ba7b-f637-4f9f-b616-94109bfb8898 25cb572c-99a3-4fe6-8e7f-87ed37ab2d17 15 73623618 73623618 C T SNP LOC100128562 XM_001726845.1 human genbank 54_36p -1 model silent c.390 p.S130 0.000 NULL PatternScan_LECTIN_LEGUME_BETA - no_errors 546 93 14.51 161 128 44.29 7 3 30.00 FAM57B 0 genome.wustl.edu 36 16 29944069 29944069 + Missense_Mutation SNP C C T TCGA-AB-2981-03A-01D-0739-09 TCGA-AB-2981-11A-01D-0739-09 C C C T C C Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 7212ba7b-f637-4f9f-b616-94109bfb8898 25cb572c-99a3-4fe6-8e7f-87ed37ab2d17 16 29944069 29944069 C T SNP FAM57B NM_031478.4 human genbank 54_36p -1 validated missense c.761 p.R254H 0.997 HMMPfam_TRAM_LAG1_CLN8,HMMSmart_SM00724 HMMPfam_TRAM_LAG1_CLN8,HMMSmart_SM00724 - no_errors 91 26 22.22 31 29 48.33 NA NA NA NPM1 0 genome.wustl.edu 36 5 170770152 170770153 + Frame_Shift_Ins INS - - TCTG TCGA-AB-2981-03A-01D-0739-09 TCGA-AB-2981-11A-01D-0739-09 - - - TCTG - - Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 7212ba7b-f637-4f9f-b616-94109bfb8898 25cb572c-99a3-4fe6-8e7f-87ed37ab2d17 5 170770152 170770153 - TCTG INS NPM1 NM_002520.1 human genbank 54_36p +1 validated frame_shift_ins c.863_864 p.W288fs 1.000:1.000 NULL HMMPfam_Nucleoplasmin,superfamily_Nucleoplasmin-like core domain - no_errors NA NA NA NA NA NA NA NA NA FLT3 0 genome.wustl.edu 36 13 27506311 27506312 + In_Frame_Ins INS - - ATTCATATTCTCTGAAATCAACGTAGAAGTACTCATTATCTGAGGAGCCGGCCA TCGA-AB-2981-03A-01D-0739-09 TCGA-AB-2981-11A-01D-0739-09 - - - ATTCATATTCTCTGAAATCAACGTAGAAGTACTCATTATCTGAGGAGCCGGCCA - - Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 7212ba7b-f637-4f9f-b616-94109bfb8898 25cb572c-99a3-4fe6-8e7f-87ed37ab2d17 13 27506311 27506312 - ATTCATATTCTCTGAAATCAACGTAGAAGTACTCATTATCTGAGGAGCCGGCCA INS FLT3 NM_004119.2 human genbank 54_36p -1 reviewed in_frame_ins c.1745_1744 p.T582in_frame_insMAGSSDNEYFYVDFREYES 0.986:0.998 superfamily_Kinase_like HMMPfam_Pkinase_Tyr,HMMSmart_TyrKc,PatternScan_RECEPTOR_TYR_KIN_III,PatternScan_PROTEIN_KINASE_TYR,superfamily_Kinase_like,HMMPfam_ig,PatternScan_PROTEIN_KINASE_ATP,superfamily_SSF48726 - no_errors NA NA NA NA NA NA NA NA NA