Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	NormalRefReads_WU	NormalVarReads_WU	NormalVAF_WU	TumorRefReads_WU	TumorVarReads_WU	TumorVAF_WU	RNARefReads_WU	RNAVarReads_WU	RNAVAF_WU
SOS1	0	genome.wustl.edu	36	2	39103418	39103418	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2990-03A-01D-0739-09	TCGA-AB-2990-11A-01D-0739-09	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	8b0e6903-5e1e-4f8b-8f17-8c2442507379	7ff43be0-1381-4220-a165-9a9e17909534	2	39103418	39103418	C	T	SNP	SOS1	NM_005633.3	human	genbank	54_36p	-1	reviewed	missense	c.1655	p.R552K	1.000	NULL	HMMPfam_RhoGEF,HMMSmart_SM00325,superfamily_DBL homology domain (DH-domain),HMMPfam_RasGEF_N,HMMSmart_SM00229,HMMPfam_PH,HMMSmart_SM00233,HMMPfam_RasGEF,HMMSmart_SM00147,HMMPfam_Histone,superfamily_Ras GEF,superfamily_Histone-fold,PatternScan_RASGEF,superfamily_PH domain-like	-	no_errors	436	31	6.64	630	438	41.01	16	9	36.00
EPB41L5	0	genome.wustl.edu	36	2	120565690	120565690	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2990-03A-01D-0739-09	TCGA-AB-2990-11A-01D-0739-09	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	8b0e6903-5e1e-4f8b-8f17-8c2442507379	7ff43be0-1381-4220-a165-9a9e17909534	2	120565690	120565690	G	A	SNP	EPB41L5	NM_020909.2	human	genbank	54_36p	+1	provisional	missense	c.1133	p.R378Q	0.995	HMMPfam_FA	HMMPfam_FA,HMMPfam_FERM_N,HMMPfam_FERM_C,PatternScan_FERM_1,PatternScan_FERM_2,HMMPfam_FERM_M,superfamily_Second domain of FERM,HMMSmart_SM00295,superfamily_PH domain-like,superfamily_Ubiquitin-like	-	no_errors	443	45	9.22	921	494	34.91	2	3	60.00
IDH1	0	genome.wustl.edu	36	2	208821358	208821358	+	Missense_Mutation	SNP	G	G	C	rs121913499		TCGA-AB-2990-03A-01D-0739-09	TCGA-AB-2990-11A-01D-0739-09	G	G	G	C	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	8b0e6903-5e1e-4f8b-8f17-8c2442507379	7ff43be0-1381-4220-a165-9a9e17909534	2	208821358	208821358	G	C	SNP	IDH1	NM_005896.2	human	genbank	54_36p	-1	reviewed	missense	c.394	p.R132G	1.000	HMMPfam_Iso_dh,superfamily_Isocitrate/Isopropylmalate dehydrogenase-like	HMMPfam_Iso_dh,PatternScan_IDH_IMDH,superfamily_Isocitrate/Isopropylmalate dehydrogenase-like	-	no_errors	441	50	10.18	580	405	41.12	35	36	50.70
CADM2	0	genome.wustl.edu	36	3	86197523	86197523	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2990-03A-01D-0739-09	TCGA-AB-2990-11A-01D-0739-09	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	8b0e6903-5e1e-4f8b-8f17-8c2442507379	7ff43be0-1381-4220-a165-9a9e17909534	3	86197523	86197523	C	T	SNP	CADM2	NM_153184.2	human	genbank	54_36p	+1	validated	missense	c.1148	p.T383M	1.000	NULL	HMMSmart_4.1m,HMMSmart_IGc2,HMMSmart_IG,HMMPfam_V-set,HMMPfam_ig,HMMPfam_C2-set_2,superfamily_SSF48726	-	no_errors	433	35	7.46	428	303	41.45	1	0	0.00
ZNF462	0	genome.wustl.edu	36	9	108731052	108731052	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2990-03A-01D-0739-09	TCGA-AB-2990-11A-01D-0739-09	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	8b0e6903-5e1e-4f8b-8f17-8c2442507379	7ff43be0-1381-4220-a165-9a9e17909534	9	108731052	108731052	C	T	SNP	ZNF462	NM_021224.4	human	genbank	54_36p	+1	validated	missense	c.5038	p.R1680C	1.000	PatternScan_ZINC_FINGER_C2H2_1,HMMSmart_SM00355,superfamily_C2H2 and C2HC zinc fingers,superfamily_beta-sandwich domain of Sec23/24	HMMPfam_zf-C2H2,PatternScan_ZINC_FINGER_C2H2_1,HMMSmart_SM00355,superfamily_C2H2 and C2HC zinc fingers,superfamily_beta-sandwich domain of Sec23/24	-	no_errors	567	61	9.71	582	367	38.63	NA	NA	NA
CALB2	0	genome.wustl.edu	36	16	69977001	69977001	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2990-03A-01D-0739-09	TCGA-AB-2990-11A-01D-0739-09	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	8b0e6903-5e1e-4f8b-8f17-8c2442507379	7ff43be0-1381-4220-a165-9a9e17909534	16	69977001	69977001	C	T	SNP	CALB2	NM_007088.3	human	genbank	54_36p	+1	reviewed	missense	c.554	p.T185M	0.999	NULL	HMMSmart_EFh,PatternScan_EF_HAND_1,HMMPfam_efhand,superfamily_SSF47473	-	no_errors	1079	108	9.10	909	629	40.82	NA	NA	NA
ANKRD24	0	genome.wustl.edu	36	19	4137441	4137441	+	Nonsense_Mutation	SNP	C	C	T			TCGA-AB-2990-03A-01D-0739-09	TCGA-AB-2990-11A-01D-0739-09	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	8b0e6903-5e1e-4f8b-8f17-8c2442507379	7ff43be0-1381-4220-a165-9a9e17909534	19	4137441	4137441	C	T	SNP	ANKRD24	NM_133475.1	human	genbank	54_36p	+1	provisional	nonsense	c.19	p.R7*	0.921	NULL	HMMPfam_Ank,HMMSmart_SM00248,superfamily_Ankyrin repeat	-	no_errors	447	58	11.49	364	257	41.38	NA	NA	NA
LAMA5	0	genome.wustl.edu	36	20	60333829	60333829	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2990-03A-01D-0739-09	TCGA-AB-2990-11A-01D-0739-09	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	8b0e6903-5e1e-4f8b-8f17-8c2442507379	7ff43be0-1381-4220-a165-9a9e17909534	20	60333829	60333829	C	T	SNP	LAMA5	NM_005560.3	human	genbank	54_36p	-1	reviewed	missense	c.5467	p.A1823T	0.013	HMMPfam_Laminin_B	HMMPfam_Laminin_B,PatternScan_TNFR_NGFR_1,HMMSmart_SM00282,HMMPfam_Laminin_EGF,HMMSmart_SM00180,PatternScan_EGF_LAM_1,HMMSmart_SM00181,HMMPfam_Laminin_N,HMMSmart_SM00136,superfamily_Galactose-binding domain-like,superfamily_Concanavalin A-like lectins/glucanases,HMMPfam_Laminin_I,HMMPfam_Laminin_II,HMMPfam_Laminin_G_2,PatternScan_EGF_1,PatternScan_EGF_2,HMMSmart_SM00281,superfamily_EGF/Laminin	-	no_errors	66	6	8.22	56	41	41.84	4	1	20.00
NPM1	0	genome.wustl.edu	36	5	170770152	170770153	+	Frame_Shift_Ins	INS	-	-	TCTG			TCGA-AB-2990-03A-01D-0739-09	TCGA-AB-2990-11A-01D-0739-09	-	-	-	TCTG	-	-	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	8b0e6903-5e1e-4f8b-8f17-8c2442507379	7ff43be0-1381-4220-a165-9a9e17909534	5	170770152	170770153	-	TCTG	INS	NPM1	NM_002520.1	human	genbank	54_36p	+1	validated	frame_shift_ins	c.863_864	p.W288fs	1.000:1.000	NULL	HMMPfam_Nucleoplasmin,superfamily_Nucleoplasmin-like core domain	-	no_errors	NA	NA	NA	NA	NA	NA	NA	NA	NA