Hugo_Symbol Entrez_Gene_Id Center NCBI_Build Chromosome Start_Position End_Position Strand Variant_Classification Variant_Type Reference_Allele Tumor_Seq_Allele1 Tumor_Seq_Allele2 dbSNP_RS dbSNP_Val_Status Tumor_Sample_Barcode Matched_Norm_Sample_Barcode Match_Norm_Seq_Allele1 Match_Norm_Seq_Allele2 Tumor_Validation_Allele1 Tumor_Validation_Allele2 Match_Norm_Validation_Allele1 Match_Norm_Validation_Allele2 Verification_Status Validation_Status Mutation_Status Sequencing_Phase Sequence_Source Validation_Method Score BAM_File Sequencer Tumor_Sample_UUID Matched_Norm_Sample_UUID chromosome_name start stop reference variant type gene_name transcript_name transcript_species transcript_source transcript_version strand transcript_status trv_type c_position amino_acid_change ucsc_cons domain all_domains deletion_substructures transcript_error NormalRefReads_WU NormalVarReads_WU NormalVAF_WU TumorRefReads_WU TumorVarReads_WU TumorVAF_WU RNARefReads_WU RNAVarReads_WU RNAVAF_WU CYLC1 0 genome.wustl.edu 36 X 83015361 83015361 + Missense_Mutation SNP C C A TCGA-AB-3012-03A-01D-0739-09 TCGA-AB-3012-11A-01D-0739-09 C C C A C C Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 1ea97951-9a33-48eb-b1da-eab8566781bf 673432d1-fa29-474c-a1f2-b042f2a57cdb X 83015361 83015361 C A SNP CYLC1 NM_021118.1 human genbank 54_36p +1 provisional missense c.989 p.T330K 0.027 NULL NULL - no_errors 809 2 0.25 96 734 88.43 NA NA NA CADM2 0 genome.wustl.edu 36 3 86197499 86197499 + Missense_Mutation SNP T T G TCGA-AB-3012-03A-01D-0739-09 TCGA-AB-3012-11A-01D-0739-09 T T T G T T Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 1ea97951-9a33-48eb-b1da-eab8566781bf 673432d1-fa29-474c-a1f2-b042f2a57cdb 3 86197499 86197499 T G SNP CADM2 NM_153184.2 human genbank 54_36p +1 validated missense c.1124 p.I375R 1.000 NULL HMMSmart_4.1m,HMMSmart_IGc2,HMMSmart_IG,HMMPfam_V-set,HMMPfam_ig,HMMPfam_C2-set_2,superfamily_SSF48726 - no_errors 953 3 0.31 500 378 42.95 NA NA NA FRYL 0 genome.wustl.edu 36 4 48271967 48271967 + Missense_Mutation SNP T T C TCGA-AB-3012-03A-01D-0739-09 TCGA-AB-3012-11A-01D-0739-09 T T T C T T Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 1ea97951-9a33-48eb-b1da-eab8566781bf 673432d1-fa29-474c-a1f2-b042f2a57cdb 4 48271967 48271967 T C SNP FRYL NM_015030.1 human genbank 54_36p -1 validated missense c.2770 p.M924V 1.000 superfamily_ARM repeat superfamily_ARM repeat - no_errors 390 0 0.00 582 308 34.61 18 11 37.93 GANC 0 genome.wustl.edu 36 15 40428888 40428888 + Missense_Mutation SNP G G A TCGA-AB-3012-03A-01D-0739-09 TCGA-AB-3012-11A-01D-0739-09 G G G A G G Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 1ea97951-9a33-48eb-b1da-eab8566781bf 673432d1-fa29-474c-a1f2-b042f2a57cdb 15 40428888 40428888 G A SNP GANC NM_198141.2 human genbank 54_36p +1 reviewed missense c.2434 p.E812K 1.000 NULL HMMPfam_Glyco_hydro_31,PatternScan_GLYCOSYL_HYDROL_F31_1,superfamily_(Trans)glycosidases - no_errors 1453 0 0.00 962 691 41.80 18 4 18.18 DHX34 0 genome.wustl.edu 36 19 52567974 52567974 + Missense_Mutation SNP G G A TCGA-AB-3012-03A-01D-0739-09 TCGA-AB-3012-11A-01D-0739-09 G G G A G G Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 1ea97951-9a33-48eb-b1da-eab8566781bf 673432d1-fa29-474c-a1f2-b042f2a57cdb 19 52567974 52567974 G A SNP DHX34 NM_014681.4 human genbank 54_36p +1 reviewed missense c.1942 p.V648I 0.984 NULL HMMPfam_Helicase_C,HMMSmart_SM00490,HMMPfam_HA2,HMMPfam_DUF1605,HMMSmart_SM00487,PatternScan_RUBREDOXIN,superfamily_P-loop containing nucleoside triphosphate hydrolases - no_errors 203 0 0.00 87 67 43.51 8 1 11.11 TOP3B 0 genome.wustl.edu 36 22 20654724 20654724 + Missense_Mutation SNP C C T TCGA-AB-3012-03A-01D-0739-09 TCGA-AB-3012-11A-01D-0739-09 C C C T C C Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 1ea97951-9a33-48eb-b1da-eab8566781bf 673432d1-fa29-474c-a1f2-b042f2a57cdb 22 20654724 20654724 C T SNP TOP3B NM_003935.3 human genbank 54_36p -1 reviewed missense c.439 p.V147M 0.984 superfamily_Prokaryotic type I DNA topoisomerase,HMMSmart_SM00436,HMMPfam_Toprim PatternScan_TOPOISOMERASE_I_PROK,superfamily_Prokaryotic type I DNA topoisomerase,HMMSmart_SM00436,HMMSmart_SM00437,HMMSmart_SM00493,HMMPfam_Toprim,HMMPfam_Topoisom_bac - no_errors 596 0 0.00 265 187 41.37 15 15 50.00 EWSR1 0 genome.wustl.edu 36 22 28018596 28018596 + Splice_Site SNP G G T TCGA-AB-3012-03A-01D-0739-09 TCGA-AB-3012-11A-01D-0739-09 G G G T G G Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 1ea97951-9a33-48eb-b1da-eab8566781bf 673432d1-fa29-474c-a1f2-b042f2a57cdb 22 28018596 28018596 G T SNP EWSR1 NM_005243.2 human genbank 54_36p +1 reviewed splice_site c.1164+1 e11+1 1.000 - - - no_errors 1118 0 0.00 753 176 18.95 13 9 26.47 ETV6 0 genome.wustl.edu 36 12 11883488 11883500 + Frame_Shift_Del DEL ATCGATCTCCTCA ATCGATCTCCTCA - TCGA-AB-3012-03A-01D-0739-09 TCGA-AB-3012-11A-01D-0739-09 ATCGATCTCCTCA ATCGATCTCCTCA ATCGATCTCCTCA - ATCGATCTCCTCA ATCGATCTCCTCA Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 1ea97951-9a33-48eb-b1da-eab8566781bf 673432d1-fa29-474c-a1f2-b042f2a57cdb 12 11883488 11883500 ATCGATCTCCTCA - DEL ETV6 NM_001987.4 human genbank 54_36p +1 reviewed frame_shift_del c.311_323 p.Y104fs 0.995:0.881:0.929:0.995:0.992:1.000:1.000:1.000:1.000:1.000:0.984:1.000:1.000 HMMPfam_SAM_PNT,HMMSmart_SM00251,superfamily_SAM/Pointed domain "HMMPfam_Ets,HMMSmart_SM00413,PatternScan_ETS_DOMAIN_2,HMMPfam_SAM_PNT,HMMSmart_SM00251,superfamily_SAM/Pointed domain,superfamily_""Winged helix"" DNA-binding domain" - no_errors NA NA NA NA NA NA NA NA NA SRRM2 0 genome.wustl.edu 36 16 2752700 2752701 + Frame_Shift_Ins INS - - TC TCGA-AB-3012-03A-01D-0739-09 TCGA-AB-3012-11A-01D-0739-09 - - - TC - - Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 1ea97951-9a33-48eb-b1da-eab8566781bf 673432d1-fa29-474c-a1f2-b042f2a57cdb 16 2752700 2752701 - TC INS SRRM2 NM_016333.3 human genbank 54_36p +1 validated frame_shift_ins c.2170_2171 p.S724fs 1.000:1.000 NULL HMMPfam_cwf21 - no_errors 1993 0 0.00 1128 634 35.98 430 227 34.55