Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
SLC46A1	113235	broad.mit.edu	37	17	26731690	26731690	+	Missense_Mutation	SNP	T	T	C			TCGA-PR-A5PH-01A-11D-A35D-08	TCGA-PR-A5PH-10B-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	02e189ce-0887-486f-98bc-09fa7cebb469	006fbf55-10ae-425b-bce6-2388efa68939	g.chr17:26731690T>C	ENST00000440501.1	-	2	1120	c.1025A>G	c.(1024-1026)aAc>aGc	p.N342S	SLC46A1_ENST00000321666.5_Missense_Mutation_p.N342S|SLC46A1_ENST00000584729.1_5'UTR	NM_080669.4	NP_542400.2	Q96NT5	PCFT_HUMAN	solute carrier family 46 (folate transporter), member 1	342					cellular iron ion homeostasis|folic acid metabolic process	apical plasma membrane|cytoplasm|integral to membrane	folic acid binding|folic acid transporter activity|heme transporter activity			lung(5)	5	all_lung(13;0.000533)|Lung NSC(42;0.00171)			UCEC - Uterine corpus endometrioid carcinoma (53;0.153)	Folic Acid(DB00158)	CCCCAGGATGTTGAAGGCCAG	0.597000													8	13					0	0	1	0	0
PWWP2B	170394	broad.mit.edu	37	10	134218293	134218293	+	Missense_Mutation	SNP	A	A	C			TCGA-PR-A5PH-01A-11D-A35D-08	TCGA-PR-A5PH-10B-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	02e189ce-0887-486f-98bc-09fa7cebb469	006fbf55-10ae-425b-bce6-2388efa68939	g.chr10:134218293A>C	ENST00000305233.5	+	2	348	c.289A>C	c.(289-291)Acc>Ccc	p.T97P	PWWP2B_ENST00000368609.4_Missense_Mutation_p.T97P	NM_138499.3	NP_612508.3	Q6NUJ5	PWP2B_HUMAN	PWWP domain containing 2B	97	Pro-rich.									central_nervous_system(1)|endometrium(1)|large_intestine(1)|lung(5)|urinary_tract(1)	9		all_cancers(35;6.69e-12)|all_epithelial(44;1.55e-08)|Lung NSC(174;0.000845)|all_lung(145;0.00144)|all_neural(114;0.0299)|Breast(234;0.106)|Colorectal(31;0.109)|Melanoma(40;0.123)|Glioma(114;0.203)|all_hematologic(284;0.224)		OV - Ovarian serous cystadenocarcinoma(35;7.49e-05)|Epithelial(32;0.00016)|all cancers(32;0.000186)		CCCCGAGACCACCCGCCCCGA	0.756000													7	11					0	0	1	0	0
FRG1BP	284802	broad.mit.edu	37	20	29625971	29625971	+	Missense_Mutation	SNP	C	C	A	rs145033899		TCGA-PR-A5PH-01A-11D-A35D-08	TCGA-PR-A5PH-10B-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	02e189ce-0887-486f-98bc-09fa7cebb469	006fbf55-10ae-425b-bce6-2388efa68939	g.chr20:29625971C>A	ENST00000278882.3	+	5	595	c.215C>A	c.(214-216)cCa>cAa	p.P72Q	FRG1B_ENST00000358464.4_Missense_Mutation_p.P72Q|FRG1B_ENST00000439954.2_Missense_Mutation_p.P77Q																endometrium(10)|kidney(21)|lung(3)|pancreas(1)|prostate(9)|urinary_tract(9)	53						CAATGGGAACCAGTCTTTCAA	0.328000													4	133					1.23904e-05	1.23904e-05	1	1	0
ATP13A4	84239	broad.mit.edu	37	3	193183900	193183900	+	Missense_Mutation	SNP	T	T	C			TCGA-PR-A5PH-01A-11D-A35D-08	TCGA-PR-A5PH-10B-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	02e189ce-0887-486f-98bc-09fa7cebb469	006fbf55-10ae-425b-bce6-2388efa68939	g.chr3:193183900T>C	ENST00000342695.4	-	11	1508	c.1186A>G	c.(1186-1188)Agg>Ggg	p.R396G	ATP13A4_ENST00000392443.3_Missense_Mutation_p.R396G|ATP13A4_ENST00000295548.3_Missense_Mutation_p.R396G	NM_032279.2	NP_115655.2	Q4VNC1	AT134_HUMAN	ATPase type 13A4	396					ATP biosynthetic process|cation transport	integral to membrane	ATP binding|ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism|metal ion binding			breast(2)|central_nervous_system(1)|cervix(1)|endometrium(6)|haematopoietic_and_lymphoid_tissue(1)|kidney(6)|large_intestine(9)|lung(27)|ovary(2)|prostate(3)|skin(11)|upper_aerodigestive_tract(2)	71	all_cancers(143;1.76e-08)|Ovarian(172;0.0386)		OV - Ovarian serous cystadenocarcinoma(49;2.72e-18)|LUSC - Lung squamous cell carcinoma(58;3.55e-06)|Lung(62;4.19e-06)	GBM - Glioblastoma multiforme(46;0.000109)		ATGGCATCCCTGTACAACTGA	0.478000													81	126					0	0	1	0	0
RP11-24M17.5	0	broad.mit.edu	37	15	76074431	76074431	+	RNA	SNP	C	C	T	rs149323153	by1000genomes	TCGA-PR-A5PH-01A-11D-A35D-08	TCGA-PR-A5PH-10B-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	02e189ce-0887-486f-98bc-09fa7cebb469	006fbf55-10ae-425b-bce6-2388efa68939	g.chr15:76074431C>T	ENST00000395215.3	+	0	610																		p.S190L(2)									CTCCAGTCCTCGAGCTGCAGA	0.547000													5	29					0	0	1	0	0
EP400	57634	broad.mit.edu	37	12	132547087	132547087	+	Silent	SNP	G	G	A	rs12366766		TCGA-PR-A5PH-01A-11D-A35D-08	TCGA-PR-A5PH-10B-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	02e189ce-0887-486f-98bc-09fa7cebb469	006fbf55-10ae-425b-bce6-2388efa68939	g.chr12:132547087G>A	ENST00000333577.4	+	48	8392	c.8283G>A	c.(8281-8283)caG>caA	p.Q2761Q	EP400_ENST00000389562.2_Silent_p.Q2724Q|EP400_ENST00000389561.2_Silent_p.Q2725Q|EP400_ENST00000330386.6_Silent_p.Q2644Q|EP400_ENST00000332482.4_Silent_p.Q2688Q			Q96L91	EP400_HUMAN	E1A binding protein p400	2761	Interaction with ZNF42 (By similarity).|Poly-Gln.				histone H2A acetylation|histone H4 acetylation|regulation of transcription, DNA-dependent	NuA4 histone acetyltransferase complex|nuclear speck	ATP binding|DNA binding|helicase activity	p.Q2724Q(16)|p.Q2725Q(1)		NS(1)|breast(6)|central_nervous_system(10)|cervix(1)|endometrium(21)|kidney(13)|large_intestine(25)|lung(56)|ovary(5)|prostate(8)|skin(6)|stomach(4)|upper_aerodigestive_tract(2)|urinary_tract(3)	161	all_neural(191;0.0982)|Medulloblastoma(191;0.163)	all_epithelial(31;0.198)		OV - Ovarian serous cystadenocarcinoma(86;3.01e-08)|Epithelial(86;3.43e-07)|all cancers(50;2.01e-06)		agcagcagcagcaacaacagc	0.562000													4	43					0	0	1	0	0
MYLK	4638	broad.mit.edu	37	3	123383036	123383036	+	Missense_Mutation	SNP	G	G	A			TCGA-PR-A5PH-01A-11D-A35D-08	TCGA-PR-A5PH-10B-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	02e189ce-0887-486f-98bc-09fa7cebb469	006fbf55-10ae-425b-bce6-2388efa68939	g.chr3:123383036G>A	ENST00000360772.3	-	24	4279	c.3901C>T	c.(3901-3903)Cgc>Tgc	p.R1301C	MYLK_ENST00000475616.1_Missense_Mutation_p.R1301C|MYLK_ENST00000360304.3_Missense_Mutation_p.R1301C|MYLK_ENST00000359169.1_Missense_Mutation_p.R1301C|MYLK_ENST00000354792.5_Missense_Mutation_p.R101C|MYLK_ENST00000346322.5_Missense_Mutation_p.R1232C			Q15746	MYLK_HUMAN	myosin light chain kinase	1301	Actin-binding (calcium/calmodulin- insensitive) (By similarity).|Ig-like C2-type 8.				aorta smooth muscle tissue morphogenesis|muscle contraction	cytosol	actin binding|ATP binding|calmodulin binding|metal ion binding|myosin light chain kinase activity			NS(2)|breast(4)|central_nervous_system(1)|endometrium(24)|haematopoietic_and_lymphoid_tissue(1)|kidney(4)|large_intestine(17)|lung(37)|ovary(7)|prostate(3)|skin(5)|stomach(1)|upper_aerodigestive_tract(5)|urinary_tract(2)	113		Lung NSC(201;0.0496)		GBM - Glioblastoma multiforme(114;0.0736)		TGCTCCTGGCGCGCGGCCAGG	0.627000													4	114					0	0	1	0	0
ACTR1B	10120	broad.mit.edu	37	2	98275013	98275013	+	Silent	SNP	G	G	A			TCGA-PR-A5PH-01A-11D-A35D-08	TCGA-PR-A5PH-10B-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	02e189ce-0887-486f-98bc-09fa7cebb469	006fbf55-10ae-425b-bce6-2388efa68939	g.chr2:98275013G>A	ENST00000289228.5	-	6	750	c.534C>T	c.(532-534)caC>caT	p.H178H		NM_005735.3	NP_005726.1	P42025	ACTY_HUMAN	ARP1 actin-related protein 1 homolog B, centractin beta (yeast)	178						centrosome|dynactin complex	ATP binding|protein binding			endometrium(1)|large_intestine(5)|lung(7)|ovary(1)|skin(1)	15						GCATGATGGAGTGAGGCATGG	0.602000													27	42					0	0	1	0	0
MERTK	10461	broad.mit.edu	37	2	112755020	112755020	+	Missense_Mutation	SNP	C	C	T			TCGA-PR-A5PH-01A-11D-A35D-08	TCGA-PR-A5PH-10B-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	02e189ce-0887-486f-98bc-09fa7cebb469	006fbf55-10ae-425b-bce6-2388efa68939	g.chr2:112755020C>T	ENST00000295408.4	+	10	1828	c.1571C>T	c.(1570-1572)gCc>gTc	p.A524V	MERTK_ENST00000409780.1_Missense_Mutation_p.A348V|MERTK_ENST00000421804.2_Missense_Mutation_p.A524V			Q12866	MERTK_HUMAN	c-mer proto-oncogene tyrosine kinase	524					cell surface receptor linked signaling pathway|cell-cell signaling|leukocyte migration	integral to plasma membrane|soluble fraction	ATP binding|transmembrane receptor protein tyrosine kinase activity			breast(1)|endometrium(3)|kidney(2)|large_intestine(6)|liver(1)|lung(18)|pancreas(1)|skin(1)|stomach(2)|upper_aerodigestive_tract(1)|urinary_tract(10)	46						ATCTCCTTGGCCATCAGAAAA	0.433000													4	85					0	0	1	0	0
CDKN2C	1031	broad.mit.edu	37	1	51439844	51439844	+	Missense_Mutation	SNP	G	G	A			TCGA-PR-A5PH-01A-11D-A35D-08	TCGA-PR-A5PH-10B-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	02e189ce-0887-486f-98bc-09fa7cebb469	006fbf55-10ae-425b-bce6-2388efa68939	g.chr1:51439844G>A	ENST00000262662.1	+	4	2443	c.409G>A	c.(409-411)Ggg>Agg	p.G137R	CDKN2C_ENST00000396148.1_Missense_Mutation_p.G137R|CDKN2C_ENST00000371761.3_Missense_Mutation_p.G137R			P42773	CDN2C_HUMAN	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	137					cell cycle arrest|G1 phase of mitotic cell cycle|G1/S transition of mitotic cell cycle|induction of apoptosis|negative regulation of cell growth|negative regulation of cell proliferation|regulation of cyclin-dependent protein kinase activity	cytosol|nucleus	cyclin-dependent protein kinase inhibitor activity|protein kinase binding	p.0?(11)|p.?(1)		central_nervous_system(8)|haematopoietic_and_lymphoid_tissue(5)|kidney(2)|large_intestine(2)|lung(2)|ovary(2)|prostate(1)|thyroid(1)	23				GBM - Glioblastoma multiforme(3;3.61e-13)|all cancers(3;0.00151)		GAACCATAAGGGGGACACCGC	0.577000			D		"""glioma, MM"""								10	13					0	0	1	0	0
DGUOK	1716	broad.mit.edu	37	2	74154050	74154050	+	Missense_Mutation	SNP	C	C	T			TCGA-PR-A5PH-01A-11D-A35D-08	TCGA-PR-A5PH-10B-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	02e189ce-0887-486f-98bc-09fa7cebb469	006fbf55-10ae-425b-bce6-2388efa68939	g.chr2:74154050C>T	ENST00000264093.4	+	1	98	c.13C>T	c.(13-15)Cgc>Tgc	p.R5C	DGUOK_ENST00000348222.1_Missense_Mutation_p.R5C|DGUOK_ENST00000356837.6_Missense_Mutation_p.R5C|DGUOK_ENST00000462685.1_3'UTR	NM_080916.2	NP_550438.1	Q16854	DGUOK_HUMAN	deoxyguanosine kinase	5					guanosine metabolic process|purine base metabolic process|purine deoxyribonucleoside metabolic process|purine-containing compound salvage	mitochondrial matrix	ATP binding|deoxyguanosine kinase activity|phosphotransferase activity, alcohol group as acceptor			endometrium(1)|lung(5)|prostate(1)|upper_aerodigestive_tract(1)	8						GGCCGCGGGCCGCCTCTTTCT	0.657000													13	23					0	0	1	0	0
ZNF574	64763	broad.mit.edu	37	19	42584207	42584207	+	Silent	SNP	G	G	A			TCGA-PR-A5PH-01A-11D-A35D-08	TCGA-PR-A5PH-10B-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	02e189ce-0887-486f-98bc-09fa7cebb469	006fbf55-10ae-425b-bce6-2388efa68939	g.chr19:42584207G>A	ENST00000600245.1	+	2	2104	c.1449G>A	c.(1447-1449)cgG>cgA	p.R483R	ZNF574_ENST00000359044.4_Silent_p.R483R|CTB-59C6.3_ENST00000594531.1_RNA|ZNF574_ENST00000222339.7_Silent_p.R573R			Q6ZN55	ZN574_HUMAN	zinc finger protein 574	483					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			endometrium(4)|kidney(1)|large_intestine(3)|lung(6)|pancreas(1)|prostate(1)|skin(2)|stomach(1)|upper_aerodigestive_tract(1)	20		Prostate(69;0.059)				AGCTGACCCGGCACCAACGTT	0.597000													4	105					0	0	1	0	0
NBPF20	100288142	broad.mit.edu	37	1	148252785	148252785	+	Missense_Mutation	SNP	T	T	C			TCGA-PR-A5PH-01A-11D-A35D-08	TCGA-PR-A5PH-10B-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	02e189ce-0887-486f-98bc-09fa7cebb469	006fbf55-10ae-425b-bce6-2388efa68939	g.chr1:148252785T>C	ENST00000369202.1	-	110	13764	c.13567A>G	c.(13567-13569)Aaa>Gaa	p.K4523E						neuroblastoma breakpoint family, member 20											breast(1)|cervix(2)|endometrium(6)|kidney(1)|large_intestine(5)|lung(10)|prostate(1)|urinary_tract(1)	27						cttcttcttttcttctttgat	0.418000													5	73					0	0	1	0	0
FAM105B	90268	broad.mit.edu	37	5	14690382	14690382	+	Missense_Mutation	SNP	C	C	G			TCGA-PR-A5PH-01A-11D-A35D-08	TCGA-PR-A5PH-10B-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	02e189ce-0887-486f-98bc-09fa7cebb469	006fbf55-10ae-425b-bce6-2388efa68939	g.chr5:14690382C>G	ENST00000284274.4	+	6	907	c.829C>G	c.(829-831)Ctc>Gtc	p.L277V		NM_138348.4	NP_612357.4	Q96BN8	F105B_HUMAN	family with sequence similarity 105, member B	277										breast(1)|kidney(1)|large_intestine(3)|lung(6)|ovary(2)|upper_aerodigestive_tract(1)	14	Lung NSC(4;0.00696)					GAGGAACCACCTCAACCAGGT	0.423000													20	44					0	0	1	0	0
PCDH11Y	83259	broad.mit.edu	37	Y	4968046	4968046	+	Silent	SNP	C	C	T			TCGA-PR-A5PH-01A-11D-A35D-08	TCGA-PR-A5PH-10B-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	02e189ce-0887-486f-98bc-09fa7cebb469	006fbf55-10ae-425b-bce6-2388efa68939	g.chrY:4968046C>T	ENST00000333703.4	+	5	2907	c.2394C>T	c.(2392-2394)acC>acT	p.T798T	PCDH11Y_ENST00000215473.6_Silent_p.T809T|PCDH11Y_ENST00000362095.5_Silent_p.T809T	NM_001278619.1|NM_032971.2	NP_001265548.1|NP_116753.1	Q9BZA8	PC11Y_HUMAN	protocadherin 11 Y-linked	809	Cadherin 7.				homophilic cell adhesion	integral to membrane|plasma membrane	calcium ion binding			autonomic_ganglia(1)|kidney(2)|large_intestine(7)|lung(14)|prostate(1)|skin(1)|upper_aerodigestive_tract(1)	27						AGTCAGTGACCAATGCTACAC	0.423000													4	73					0	0	1	0	0
DOCK9	23348	broad.mit.edu	37	13	99538837	99538837	+	Silent	SNP	G	G	A			TCGA-PR-A5PH-01A-11D-A35D-08	TCGA-PR-A5PH-10B-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	02e189ce-0887-486f-98bc-09fa7cebb469	006fbf55-10ae-425b-bce6-2388efa68939	g.chr13:99538837G>A	ENST00000376460.1	-	19	2165	c.2085C>T	c.(2083-2085)agC>agT	p.S695S	DOCK9_ENST00000442173.1_Silent_p.S695S|DOCK9_ENST00000339416.2_Silent_p.S696S|DOCK9_ENST00000448493.2_Silent_p.S707S	NM_001130048.1|NM_015296.2	NP_001123520.1|NP_056111.1	Q9BZ29	DOCK9_HUMAN	dedicator of cytokinesis 9	696	DHR-1.				blood coagulation	cytosol|endomembrane system|membrane	GTP binding|GTPase binding|guanyl-nucleotide exchange factor activity			breast(3)|central_nervous_system(1)|endometrium(11)|haematopoietic_and_lymphoid_tissue(1)|kidney(5)|large_intestine(12)|lung(18)|prostate(3)|skin(1)|stomach(1)|upper_aerodigestive_tract(2)|urinary_tract(1)	59	all_neural(89;0.101)|Medulloblastoma(90;0.18)|Lung SC(71;0.184)					CAGCAAAGGCGCTTCTTGTGA	0.383000													15	20					0	0	1	0	0
MST1L	11223	broad.mit.edu	37	1	17085189	17085189	+	RNA	SNP	A	A	G			TCGA-PR-A5PH-01A-11D-A35D-08	TCGA-PR-A5PH-10B-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	02e189ce-0887-486f-98bc-09fa7cebb469	006fbf55-10ae-425b-bce6-2388efa68939	g.chr1:17085189A>G	ENST00000455405.2	-	0	87																		p.S428P(1)									TCCAGGATTGATGGCGGCTGG	0.572000													4	24					0	0	1	0	0
RP11-24M17.5	0	broad.mit.edu	37	15	76074470	76074470	+	RNA	SNP	A	A	G			TCGA-PR-A5PH-01A-11D-A35D-08	TCGA-PR-A5PH-10B-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	02e189ce-0887-486f-98bc-09fa7cebb469	006fbf55-10ae-425b-bce6-2388efa68939	g.chr15:76074470A>G	ENST00000395215.3	+	0	649																		p.Q203R(4)									CGGTTACAGCAGACCATAAAG	0.577000													4	33					0	0	1	0	0
PTPN13	5783	broad.mit.edu	37	4	87701607	87701607	+	Missense_Mutation	SNP	A	A	G			TCGA-PR-A5PH-01A-11D-A35D-08	TCGA-PR-A5PH-10B-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	02e189ce-0887-486f-98bc-09fa7cebb469	006fbf55-10ae-425b-bce6-2388efa68939	g.chr4:87701607A>G	ENST00000436978.1	+	36	6439	c.5959A>G	c.(5959-5961)Aag>Gag	p.K1987E	PTPN13_ENST00000411767.2_Missense_Mutation_p.K1982E|PTPN13_ENST00000511467.1_Missense_Mutation_p.K1987E|PTPN13_ENST00000316707.6_Missense_Mutation_p.K1791E|PTPN13_ENST00000427191.2_Missense_Mutation_p.K1963E	NM_080683.2|NM_080685.2	NP_542414.1|NP_542416.1	Q12923	PTN13_HUMAN	protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)	1982						cytoplasm|cytoskeleton|plasma membrane	protein binding|protein tyrosine phosphatase activity			NS(4)|breast(3)|central_nervous_system(1)|cervix(2)|endometrium(6)|haematopoietic_and_lymphoid_tissue(1)|kidney(12)|large_intestine(23)|lung(24)|ovary(4)|prostate(3)|skin(7)|upper_aerodigestive_tract(1)|urinary_tract(2)	93		Hepatocellular(203;0.114)|all_hematologic(202;0.21)|Acute lymphoblastic leukemia(40;0.242)		OV - Ovarian serous cystadenocarcinoma(123;0.00082)		TTCAGCTCCAAAGTCAaccaa	0.403000													6	15					0	0	1	0	0
OR8J3	81168	broad.mit.edu	37	11	55904696	55904696	+	Missense_Mutation	SNP	A	A	G			TCGA-PR-A5PH-01A-11D-A35D-08	TCGA-PR-A5PH-10B-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	02e189ce-0887-486f-98bc-09fa7cebb469	006fbf55-10ae-425b-bce6-2388efa68939	g.chr11:55904696A>G	ENST00000301529.1	-	1	498	c.499T>C	c.(499-501)Tct>Cct	p.S167P		NM_001004064.1	NP_001004064.1	Q8NGG0	OR8J3_HUMAN	olfactory receptor, family 8, subfamily J, member 3	167					sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			NS(1)|breast(2)|central_nervous_system(1)|endometrium(5)|kidney(3)|large_intestine(1)|lung(38)|pancreas(1)|prostate(1)|skin(2)|stomach(3)|upper_aerodigestive_tract(1)	59	Esophageal squamous(21;0.00693)					GAGCAATAAGACACAGAGAAT	0.413000													4	62					0	0	1	0	0
LMNA	4000	broad.mit.edu	37	1	156106111	156106111	+	Nonsense_Mutation	SNP	G	G	T			TCGA-PR-A5PH-01A-11D-A35D-08	TCGA-PR-A5PH-10B-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	02e189ce-0887-486f-98bc-09fa7cebb469	006fbf55-10ae-425b-bce6-2388efa68939	g.chr1:156106111G>T	ENST00000368300.4	+	7	1476	c.1264G>T	c.(1264-1266)Gag>Tag	p.E422*	LMNA_ENST00000473598.2_Nonsense_Mutation_p.E323*|LMNA_ENST00000496738.1_3'UTR|LMNA_ENST00000368297.1_Nonsense_Mutation_p.E341*|LMNA_ENST00000392353.3_Nonsense_Mutation_p.E341*|LMNA_ENST00000368299.3_Nonsense_Mutation_p.E422*|LMNA_ENST00000368301.2_Nonsense_Mutation_p.E422*|LMNA_ENST00000361308.4_Nonsense_Mutation_p.E422*|LMNA_ENST00000347559.2_Nonsense_Mutation_p.E422*|LMNA_ENST00000448611.2_Nonsense_Mutation_p.E310*	NM_170707.3	NP_733821.1	P02545	LMNA_HUMAN	lamin A/C	422	Tail.				cellular component disassembly involved in apoptosis|cellular response to hypoxia|establishment or maintenance of microtubule cytoskeleton polarity|muscle organ development|positive regulation of cell aging|regulation of apoptosis|regulation of cell migration	cytoplasm|lamin filament|nuclear envelope|perinuclear region of cytoplasm	protein binding|structural molecule activity			NS(1)|endometrium(1)|kidney(1)|lung(3)|ovary(4)	10	Hepatocellular(266;0.158)					GCGCAAACTGGAGTCCACTGA	0.657000									Werner syndrome;Hutchinson-Gilford Progeria Syndrome				14	31					9.05144e-12	9.39957e-12	1	1	0
COL9A2	1298	broad.mit.edu	37	1	40768483	40768484	+	Splice_Site	INS	-	-	GGAG	rs3831927	by1000genomes	TCGA-PR-A5PH-01A-11D-A35D-08	TCGA-PR-A5PH-10B-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	02e189ce-0887-486f-98bc-09fa7cebb469	006fbf55-10ae-425b-bce6-2388efa68939	g.chr1:40768483_40768484insGGAG	ENST00000372748.3	-	30	1700		c.e30-2		COL9A2_ENST00000466267.1_Splice_Site	NM_001852.3	NP_001843.1	Q14055	CO9A2_HUMAN	collagen, type IX, alpha 2						axon guidance|skeletal system development	collagen type IX				endometrium(4)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(3)|lung(5)|ovary(4)|stomach(2)|urinary_tract(2)	22	Lung NSC(20;4.38e-06)|Ovarian(52;0.00167)|all_hematologic(146;0.0501)|Acute lymphoblastic leukemia(166;0.074)	Myeloproliferative disorder(586;0.0255)	OV - Ovarian serous cystadenocarcinoma(33;2.08e-17)			CCAGTTGCTCTggagggaggga	0.649													3	3	---	---	---	---					
FAM162B	221303	broad.mit.edu	37	6	117086577	117086577	+	Frame_Shift_Del	DEL	G	G	-			TCGA-PR-A5PH-01A-11D-A35D-08	TCGA-PR-A5PH-10B-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	02e189ce-0887-486f-98bc-09fa7cebb469	006fbf55-10ae-425b-bce6-2388efa68939	g.chr6:117086577delG	ENST00000368557.4	-	1	309	c.163delC	c.(163-165)aafs	p.Q55fs		NM_001085480.2	NP_001078949.1	Q5T6X4	F162B_HUMAN	family with sequence similarity 162, member B	55						integral to membrane				large_intestine(2)|lung(4)	6						CCGTGACCTTGGGGCCCAGAA	0.766													2	4	---	---	---	---					
IGDCC4	57722	broad.mit.edu	37	15	65689295	65689295	+	Frame_Shift_Del	DEL	G	G	-			TCGA-PR-A5PH-01A-11D-A35D-08	TCGA-PR-A5PH-10B-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	02e189ce-0887-486f-98bc-09fa7cebb469	006fbf55-10ae-425b-bce6-2388efa68939	g.chr15:65689295delG	ENST00000352385.2	-	6	1083	c.874delC	c.(874-876)tgfs	p.L292fs		NM_020962.1	NP_066013.1	Q8TDY8	IGDC4_HUMAN	immunoglobulin superfamily, DCC subclass, member 4	292	Ig-like C2-type 3.					integral to membrane|plasma membrane				NS(1)|central_nervous_system(1)|endometrium(1)|large_intestine(7)|lung(24)|ovary(1)|pancreas(1)|prostate(3)|skin(2)|upper_aerodigestive_tract(3)	44						GTGCGGCCCAGGACGATGACA	0.652													2	4	---	---	---	---