Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
APOB	338	broad.mit.edu	37	2	21229684	21229684	+	Silent	SNP	G	G	T			TCGA-SA-A6C2-01A-11D-A35I-08	TCGA-SA-A6C2-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b3ca65fd-7d56-476d-86c9-8a7d2eab5435	4354bce8-2d8c-4cd4-86c5-f9f7bb0aaf2c	g.chr2:21229684G>T	ENST00000233242.1	-	26	10183	c.10056C>A	c.(10054-10056)acC>acA	p.T3352T		NM_000384.2	NP_000375.2	P04114	APOB_HUMAN	apolipoprotein B	3352					cholesterol homeostasis|cholesterol metabolic process|leukocyte migration|low-density lipoprotein particle clearance|low-density lipoprotein particle remodeling|platelet activation|positive regulation of cholesterol storage|positive regulation of macrophage derived foam cell differentiation|receptor-mediated endocytosis|response to virus	chylomicron remnant|clathrin-coated endocytic vesicle membrane|endoplasmic reticulum lumen|endoplasmic reticulum membrane|endosome lumen|endosome membrane|intermediate-density lipoprotein particle|low-density lipoprotein particle|mature chylomicron|microsome|plasma membrane|very-low-density lipoprotein particle	cholesterol transporter activity|enzyme binding|heparin binding|low-density lipoprotein particle receptor binding|phospholipid binding|protein heterodimerization activity			NS(5)|autonomic_ganglia(1)|breast(6)|central_nervous_system(4)|cervix(3)|endometrium(19)|kidney(10)|large_intestine(63)|liver(5)|lung(125)|ovary(16)|pancreas(1)|prostate(5)|skin(31)|stomach(1)|upper_aerodigestive_tract(4)|urinary_tract(6)	305	Acute lymphoblastic leukemia(172;0.155)|all_hematologic(175;0.215)				Atorvastatin(DB01076)	GTTCAGCATTGGTATTCAGTG	0.368000													38	58					6.05902e-23	6.55029e-23	1	1	0
LCT	3938	broad.mit.edu	37	2	136564700	136564700	+	Nonsense_Mutation	SNP	G	G	A			TCGA-SA-A6C2-01A-11D-A35I-08	TCGA-SA-A6C2-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b3ca65fd-7d56-476d-86c9-8a7d2eab5435	4354bce8-2d8c-4cd4-86c5-f9f7bb0aaf2c	g.chr2:136564700G>A	ENST00000264162.2	-	9	4181	c.4171C>T	c.(4171-4173)Cag>Tag	p.Q1391*		NM_002299.2	NP_002290.2	P09848	LPH_HUMAN	lactase	1391	4 X approximate repeats.				carbohydrate metabolic process|polysaccharide digestion	apical plasma membrane|integral to plasma membrane|membrane fraction	cation binding|glycosylceramidase activity|lactase activity			breast(6)|central_nervous_system(3)|cervix(1)|endometrium(8)|kidney(2)|large_intestine(26)|lung(57)|ovary(7)|pancreas(2)|prostate(1)|skin(3)|upper_aerodigestive_tract(4)|urinary_tract(4)	124				BRCA - Breast invasive adenocarcinoma(221;0.169)		CTCCTCACCTGATATGCAGCA	0.572000													19	19					0	0	1	0	0
LRRN2	10446	broad.mit.edu	37	1	204587841	204587841	+	Missense_Mutation	SNP	C	C	T	rs138573874		TCGA-SA-A6C2-01A-11D-A35I-08	TCGA-SA-A6C2-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b3ca65fd-7d56-476d-86c9-8a7d2eab5435	4354bce8-2d8c-4cd4-86c5-f9f7bb0aaf2c	g.chr1:204587841C>T	ENST00000367175.1	-	1	3492	c.1280G>A	c.(1279-1281)cGa>cAa	p.R427Q	LRRN2_ENST00000367177.3_Missense_Mutation_p.R427Q|LRRN2_ENST00000367176.3_Missense_Mutation_p.R427Q			O75325	LRRN2_HUMAN	leucine rich repeat neuronal 2	427	Ig-like C2-type.				cell adhesion	integral to membrane	receptor activity			central_nervous_system(3)|endometrium(2)|haematopoietic_and_lymphoid_tissue(3)|large_intestine(3)|liver(1)|lung(22)|prostate(2)|skin(1)|upper_aerodigestive_tract(1)	38	all_cancers(21;0.0519)|Breast(84;0.112)|Prostate(682;0.19)		KIRC - Kidney renal clear cell carcinoma(13;0.0584)|Kidney(21;0.0934)|BRCA - Breast invasive adenocarcinoma(75;0.143)			GGGGAAGCTTCGTGGGGAGAT	0.652000													8	14					0	0	1	0	0
CACNA1D	776	broad.mit.edu	37	3	53766101	53766101	+	Missense_Mutation	SNP	A	A	G			TCGA-SA-A6C2-01A-11D-A35I-08	TCGA-SA-A6C2-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b3ca65fd-7d56-476d-86c9-8a7d2eab5435	4354bce8-2d8c-4cd4-86c5-f9f7bb0aaf2c	g.chr3:53766101A>G	ENST00000288139.3	+	19	2643	c.2525A>G	c.(2524-2526)gAt>gGt	p.D842G	CACNA1D_ENST00000350061.5_Missense_Mutation_p.D822G|CACNA1D_ENST00000422281.2_Missense_Mutation_p.D822G	NM_000720.2	NP_000711.1	Q01668	CAC1D_HUMAN	calcium channel, voltage-dependent, L type, alpha 1D subunit	822					axon guidance|energy reserve metabolic process|regulation of insulin secretion	voltage-gated calcium channel complex	voltage-gated calcium channel activity			breast(3)|central_nervous_system(9)|cervix(2)|endometrium(11)|kidney(7)|large_intestine(13)|liver(1)|lung(29)|ovary(6)|prostate(2)|skin(4)|upper_aerodigestive_tract(2)|urinary_tract(1)	90				BRCA - Breast invasive adenocarcinoma(193;0.00029)|KIRC - Kidney renal clear cell carcinoma(284;0.0145)|Kidney(284;0.0175)|OV - Ovarian serous cystadenocarcinoma(275;0.0613)	Verapamil(DB00661)	CCGCCTTGCGATGTGCCAGGT	0.557000													3	41					0	0	1	0	0
TMEM79	84283	broad.mit.edu	37	1	156261208	156261208	+	Missense_Mutation	SNP	G	G	A			TCGA-SA-A6C2-01A-11D-A35I-08	TCGA-SA-A6C2-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b3ca65fd-7d56-476d-86c9-8a7d2eab5435	4354bce8-2d8c-4cd4-86c5-f9f7bb0aaf2c	g.chr1:156261208G>A	ENST00000405535.2	+	4	1175	c.1004G>A	c.(1003-1005)cGc>cAc	p.R335H	C1orf85_ENST00000472870.1_Intron|TMEM79_ENST00000495881.1_3'UTR|TMEM79_ENST00000295694.5_Missense_Mutation_p.R335H|TMEM79_ENST00000357501.2_Silent_p.P96P	NM_032323.2	NP_115699.1	Q9BSE2	TMM79_HUMAN	transmembrane protein 79	335						integral to membrane				breast(1)|central_nervous_system(1)|endometrium(2)|kidney(1)|large_intestine(5)|liver(1)|lung(9)|urinary_tract(1)	21	Hepatocellular(266;0.158)					GCCGTGGGCCGCTCCTTCCGA	0.587000													4	93					0	0	1	0	0
COL12A1	1303	broad.mit.edu	37	6	75893695	75893695	+	Missense_Mutation	SNP	G	G	A			TCGA-SA-A6C2-01A-11D-A35I-08	TCGA-SA-A6C2-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b3ca65fd-7d56-476d-86c9-8a7d2eab5435	4354bce8-2d8c-4cd4-86c5-f9f7bb0aaf2c	g.chr6:75893695G>A	ENST00000322507.8	-	9	1472	c.1163C>T	c.(1162-1164)aCg>aTg	p.T388M	COL12A1_ENST00000416123.2_Missense_Mutation_p.T388M|COL12A1_ENST00000483888.2_Missense_Mutation_p.T388M|COL12A1_ENST00000345356.6_Intron	NM_004370.5	NP_004361.3	Q99715	COCA1_HUMAN	collagen, type XII, alpha 1	388	Fibronectin type-III 2.				cell adhesion|collagen fibril organization|skeletal system development	collagen type XII|extracellular space	extracellular matrix structural constituent conferring tensile strength			breast(7)|central_nervous_system(1)|endometrium(7)|haematopoietic_and_lymphoid_tissue(5)|kidney(5)|large_intestine(44)|liver(1)|lung(77)|ovary(7)|prostate(3)|skin(4)|stomach(2)|upper_aerodigestive_tract(4)|urinary_tract(2)	169						AACACTGAGCGTGGTTGTCTG	0.512000													5	112					0	0	1	0	0
DNM1P47	100216544	broad.mit.edu	37	15	102294652	102294652	+	RNA	SNP	G	G	A			TCGA-SA-A6C2-01A-11D-A35I-08	TCGA-SA-A6C2-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b3ca65fd-7d56-476d-86c9-8a7d2eab5435	4354bce8-2d8c-4cd4-86c5-f9f7bb0aaf2c	g.chr15:102294652G>A	ENST00000561463.1	+	0	2698																											CAGAGCTGCTGTCCAACCTGC	0.592000													5	5					0	0	1	0	0
KAT6A	7994	broad.mit.edu	37	8	41792302	41792302	+	Silent	SNP	A	A	G			TCGA-SA-A6C2-01A-11D-A35I-08	TCGA-SA-A6C2-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b3ca65fd-7d56-476d-86c9-8a7d2eab5435	4354bce8-2d8c-4cd4-86c5-f9f7bb0aaf2c	g.chr8:41792302A>G	ENST00000396930.3	-	18	3979	c.3436T>C	c.(3436-3438)Ttg>Ctg	p.L1146L	KAT6A_ENST00000406337.1_Silent_p.L1146L|KAT6A_ENST00000265713.2_Silent_p.L1146L	NM_001099412.1	NP_001092882.1	Q92794	MYST3_HUMAN	K(lysine) acetyltransferase 6A	1146					histone H3 acetylation|myeloid cell differentiation|negative regulation of transcription, DNA-dependent|nucleosome assembly|positive regulation of transcription, DNA-dependent|transcription, DNA-dependent	MOZ/MORF histone acetyltransferase complex|nucleosome	DNA binding|histone acetyltransferase activity|transcription coactivator activity|transcription factor binding|zinc ion binding										TTCTTTTTCAAAGGTGTGGAT	0.428000													36	184					0	0	1	0	0
KRTAP10-3	386682	broad.mit.edu	37	21	45978220	45978220	+	Missense_Mutation	SNP	G	G	A			TCGA-SA-A6C2-01A-11D-A35I-08	TCGA-SA-A6C2-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b3ca65fd-7d56-476d-86c9-8a7d2eab5435	4354bce8-2d8c-4cd4-86c5-f9f7bb0aaf2c	g.chr21:45978220G>A	ENST00000391620.1	-	1	423	c.379C>T	c.(379-381)Ccc>Tcc	p.P127S	TSPEAR_ENST00000323084.4_Intron|TSPEAR_ENST00000397916.1_Intron	NM_198696.2	NP_941969.2	P60369	KR103_HUMAN	keratin associated protein 10-3	127	18 X 5 AA repeats of C-C-X(3).					keratin filament				kidney(1)|lung(4)|prostate(1)|skin(1)	7						GAgcagacgggcacacagcag	0.657000													4	174					0	0	1	0	0
OR7G2	390882	broad.mit.edu	37	19	9213131	9213131	+	Silent	SNP	C	C	T			TCGA-SA-A6C2-01A-11D-A35I-08	TCGA-SA-A6C2-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b3ca65fd-7d56-476d-86c9-8a7d2eab5435	4354bce8-2d8c-4cd4-86c5-f9f7bb0aaf2c	g.chr19:9213131C>T	ENST00000305456.2	-	1	851	c.852G>A	c.(850-852)gtG>gtA	p.V284V		NM_001005193.1	NP_001005193.1	Q8NG99	OR7G2_HUMAN	olfactory receptor, family 7, subfamily G, member 2	263					sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			breast(1)|endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(4)|lung(5)|skin(3)	16						AGTCAGTAACCACAGAACTAA	0.468000													3	45					0	0	1	0	0
SKIV2L2	23517	broad.mit.edu	37	5	54674238	54674238	+	Missense_Mutation	SNP	T	T	G			TCGA-SA-A6C2-01A-11D-A35I-08	TCGA-SA-A6C2-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b3ca65fd-7d56-476d-86c9-8a7d2eab5435	4354bce8-2d8c-4cd4-86c5-f9f7bb0aaf2c	g.chr5:54674238T>G	ENST00000230640.5	+	17	2161	c.1907T>G	c.(1906-1908)tTg>tGg	p.L636W	SKIV2L2_ENST00000545714.1_Missense_Mutation_p.L535W	NM_015360.4	NP_056175.3	P42285	SK2L2_HUMAN	superkiller viralicidic activity 2-like 2 (S. cerevisiae)	636					maturation of 5.8S rRNA	catalytic step 2 spliceosome|nucleolus	ATP binding|ATP-dependent helicase activity|nucleic acid binding|protein binding			NS(2)|endometrium(7)|haematopoietic_and_lymphoid_tissue(2)|kidney(4)|large_intestine(5)|lung(12)|ovary(1)|prostate(4)|skin(2)|upper_aerodigestive_tract(1)|urinary_tract(1)	41		Lung NSC(810;0.000744)|Breast(144;0.181)|Prostate(74;0.194)				CTTGCCAAATTGGGTAAAGAA	0.313000													7	67					0	0	1	0	0
GGT3P	2679	broad.mit.edu	37	22	18769203	18769203	+	RNA	SNP	G	G	A	rs111245818		TCGA-SA-A6C2-01A-11D-A35I-08	TCGA-SA-A6C2-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b3ca65fd-7d56-476d-86c9-8a7d2eab5435	4354bce8-2d8c-4cd4-86c5-f9f7bb0aaf2c	g.chr22:18769203G>A	ENST00000412448.1	-	0	1083																											AGCCAGCCGCGGCAGGGTCAG	0.637000													6	48					0	0	1	0	0
LZTS3	9762	broad.mit.edu	37	20	3146605	3146605	+	Silent	SNP	C	C	T			TCGA-SA-A6C2-01A-11D-A35I-08	TCGA-SA-A6C2-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b3ca65fd-7d56-476d-86c9-8a7d2eab5435	4354bce8-2d8c-4cd4-86c5-f9f7bb0aaf2c	g.chr20:3146605C>T	ENST00000329152.3	-	2	2258	c.861G>A	c.(859-861)tcG>tcA	p.S287S	LZTS3_ENST00000360342.3_Silent_p.S287S|LZTS3_ENST00000337576.5_Silent_p.S287S	NM_014731.2	NP_055546.1																					TAGATGACGACGACCCACTCT	0.692000													12	32					0	0	1	0	0
GRIP1	23426	broad.mit.edu	37	12	66923631	66923631	+	Missense_Mutation	SNP	G	G	A			TCGA-SA-A6C2-01A-11D-A35I-08	TCGA-SA-A6C2-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b3ca65fd-7d56-476d-86c9-8a7d2eab5435	4354bce8-2d8c-4cd4-86c5-f9f7bb0aaf2c	g.chr12:66923631G>A	ENST00000359742.4	-	5	722	c.482C>T	c.(481-483)aCc>aTc	p.T161I	GRIP1_ENST00000398016.3_Missense_Mutation_p.T161I|GRIP1_ENST00000286445.7_Missense_Mutation_p.T161I			Q9Y3R0	GRIP1_HUMAN	glutamate receptor interacting protein 1	161	PDZ 2.				androgen receptor signaling pathway|intracellular signal transduction|positive regulation of transcription, DNA-dependent|synaptic transmission	cell junction|cytoplasmic membrane-bounded vesicle|cytosol|endoplasmic reticulum|postsynaptic membrane	androgen receptor binding|beta-catenin binding|protein C-terminus binding|receptor signaling complex scaffold activity|transcription coactivator activity			NS(3)|breast(2)|cervix(1)|endometrium(6)|haematopoietic_and_lymphoid_tissue(2)|kidney(2)|large_intestine(10)|lung(19)|ovary(2)|prostate(2)|skin(1)	50			GBM - Glioblastoma multiforme(2;0.00069)	GBM - Glioblastoma multiforme(28;0.0933)		AAAACCAAAGGTATTGCCTTC	0.343000													7	58					0	0	1	0	0
OR52I1	390037	broad.mit.edu	37	11	4615553	4615553	+	Silent	SNP	C	C	A			TCGA-SA-A6C2-01A-11D-A35I-08	TCGA-SA-A6C2-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b3ca65fd-7d56-476d-86c9-8a7d2eab5435	4354bce8-2d8c-4cd4-86c5-f9f7bb0aaf2c	g.chr11:4615553C>A	ENST00000450052.2	+	2	357	c.357C>A	c.(355-357)tcC>tcA	p.S119S	OR52I1_ENST00000530443.2_Silent_p.S95S			Q8NGK6	O52I1_HUMAN	olfactory receptor, family 52, subfamily I, member 1	95					sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			central_nervous_system(2)|endometrium(2)|kidney(1)|large_intestine(3)|lung(6)|ovary(1)	15		Medulloblastoma(188;0.0075)|Breast(177;0.0461)|all_neural(188;0.0577)		Epithelial(150;7.98e-12)|BRCA - Breast invasive adenocarcinoma(625;0.0284)|LUSC - Lung squamous cell carcinoma(625;0.19)		GAGACAGCTCCATCAGCTTTA	0.512000													4	112					0.014758	0.0151364	1	1	0
UGT3A2	167127	broad.mit.edu	37	5	36049138	36049138	+	Silent	SNP	G	G	A			TCGA-SA-A6C2-01A-11D-A35I-08	TCGA-SA-A6C2-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b3ca65fd-7d56-476d-86c9-8a7d2eab5435	4354bce8-2d8c-4cd4-86c5-f9f7bb0aaf2c	g.chr5:36049138G>A	ENST00000282507.3	-	4	797	c.696C>T	c.(694-696)ggC>ggT	p.G232G	UGT3A2_ENST00000513300.1_Silent_p.G198G|UGT3A2_ENST00000504954.1_Intron|UGT3A2_ENST00000545528.1_Intron	NM_174914.3	NP_777574.2	Q3SY77	UD3A2_HUMAN	UDP glycosyltransferase 3 family, polypeptide A2	232						integral to membrane	glucuronosyltransferase activity			NS(1)|autonomic_ganglia(1)|breast(1)|cervix(1)|endometrium(2)|kidney(1)|large_intestine(9)|lung(20)|ovary(2)|pancreas(1)|prostate(1)|skin(3)	43	all_lung(31;0.000179)		Lung(74;0.111)|Epithelial(62;0.113)|COAD - Colon adenocarcinoma(61;0.14)|Colorectal(62;0.202)			CTGGCCTAGAGCCTTCTGTGA	0.438000													34	46					0	0	1	0	0
HOXD11	3237	broad.mit.edu	37	2	176973665	176973665	+	Missense_Mutation	SNP	G	G	A			TCGA-SA-A6C2-01A-11D-A35I-08	TCGA-SA-A6C2-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b3ca65fd-7d56-476d-86c9-8a7d2eab5435	4354bce8-2d8c-4cd4-86c5-f9f7bb0aaf2c	g.chr2:176973665G>A	ENST00000249504.5	+	2	882	c.812G>A	c.(811-813)tGt>tAt	p.C271Y	HOXD10_ENST00000490088.2_3'UTR|HOXD11_ENST00000498438.1_3'UTR	NM_021192.2	NP_067015.2	P31277	HXD11_HUMAN	homeobox D11	271						nucleus	sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity							OV - Ovarian serous cystadenocarcinoma(117;0.0207)|Epithelial(96;0.18)	Colorectal(32;0.0521)|READ - Rectum adenocarcinoma(9;0.0678)		AAAAAGCGCTGTCCCTATACC	0.577000			T	NUP98	AML								5	69					0	0	1	0	0
TRIM16	10626	broad.mit.edu	37	17	15554470	15554470	+	Missense_Mutation	SNP	C	C	G			TCGA-SA-A6C2-01A-11D-A35I-08	TCGA-SA-A6C2-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b3ca65fd-7d56-476d-86c9-8a7d2eab5435	4354bce8-2d8c-4cd4-86c5-f9f7bb0aaf2c	g.chr17:15554470C>G	ENST00000455584.2	-	1	497	c.454G>C	c.(454-456)Gac>Cac	p.D152H	TRIM16_ENST00000336708.7_Missense_Mutation_p.D152H|TRIM16_ENST00000416464.2_Intron|TRIM16_ENST00000578237.1_Missense_Mutation_p.D152H|TRIM16_ENST00000581224.1_Intron																							TGGCAACAGTCCTGGCAGATG	0.602000													3	38					0	0	1	0	0
RAD54B	25788	broad.mit.edu	37	8	95479758	95479758	+	Missense_Mutation	SNP	A	A	T			TCGA-SA-A6C2-01A-11D-A35I-08	TCGA-SA-A6C2-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b3ca65fd-7d56-476d-86c9-8a7d2eab5435	4354bce8-2d8c-4cd4-86c5-f9f7bb0aaf2c	g.chr8:95479758A>T	ENST00000336148.5	-	2	134	c.10T>A	c.(10-12)Tct>Act	p.S4T	RAD54B_ENST00000297592.5_Missense_Mutation_p.S4T	NM_012415.3	NP_036547.1	O95073	FSBP_HUMAN	RAD54 homolog B (S. cerevisiae)	0					double-strand break repair via homologous recombination|regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA translocase activity|protein binding			breast(1)|central_nervous_system(1)|endometrium(3)|kidney(4)|large_intestine(10)|lung(15)|prostate(1)|skin(2)|upper_aerodigestive_tract(1)|urinary_tract(1)	39	Breast(36;4.5e-05)		BRCA - Breast invasive adenocarcinoma(8;0.00217)			GGTGCTGCAGATCGTCTCATA	0.373000								Direct reversal of damage;Homologous recombination					35	53					0	0	1	0	0
AKAP5	9495	broad.mit.edu	37	14	64936274	64936274	+	Missense_Mutation	SNP	T	T	G			TCGA-SA-A6C2-01A-11D-A35I-08	TCGA-SA-A6C2-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b3ca65fd-7d56-476d-86c9-8a7d2eab5435	4354bce8-2d8c-4cd4-86c5-f9f7bb0aaf2c	g.chr14:64936274T>G	ENST00000320636.5	+	1	2450	c.1162T>G	c.(1162-1164)Tat>Gat	p.Y388D	ZBTB25_ENST00000555424.1_Intron|ZBTB25_ENST00000555220.1_Intron|AKAP5_ENST00000394718.3_Missense_Mutation_p.Y388D			P24588	AKAP5_HUMAN	A kinase (PRKA) anchor protein 5	388					energy reserve metabolic process|positive regulation of cAMP biosynthetic process|positive regulation of protein kinase A signaling cascade|protein targeting|regulation of insulin secretion|signal transduction|synaptic transmission	cytosol	adenylate cyclase binding|calmodulin binding			endometrium(2)|kidney(1)|large_intestine(5)|lung(4)|stomach(1)	13				all cancers(60;0.00749)|OV - Ovarian serous cystadenocarcinoma(108;0.0095)|BRCA - Breast invasive adenocarcinoma(234;0.0449)		TTCAGAACAATATGAAACACT	0.338000													7	116					0	0	1	0	0
ACTR3C	653857	broad.mit.edu	37	7	149990455	149990455	+	Silent	SNP	T	T	C	rs146995367	by1000genomes	TCGA-SA-A6C2-01A-11D-A35I-08	TCGA-SA-A6C2-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b3ca65fd-7d56-476d-86c9-8a7d2eab5435	4354bce8-2d8c-4cd4-86c5-f9f7bb0aaf2c	g.chr7:149990455T>C	ENST00000539352.1	-	3	350	c.99A>G	c.(97-99)acA>acG	p.T33T	ACTR3C_ENST00000252071.4_Silent_p.T33T	NM_001164458.1	NP_001157930.1	Q9C0K3	ARP3C_HUMAN	ARP3 actin-related protein 3 homolog C (yeast)	33					regulation of actin filament polymerization	cytoskeleton	actin binding|ATP binding	p.T33T(1)									TCCCCGTTAATGTACGTTCAC	0.468000													3	15					0	0	1	0	0
FBF1	85302	broad.mit.edu	37	17	73914285	73914285	+	Missense_Mutation	SNP	T	T	G			TCGA-SA-A6C2-01A-11D-A35I-08	TCGA-SA-A6C2-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b3ca65fd-7d56-476d-86c9-8a7d2eab5435	4354bce8-2d8c-4cd4-86c5-f9f7bb0aaf2c	g.chr17:73914285T>G	ENST00000586717.1	-	20	2435	c.2162A>C	c.(2161-2163)gAc>gCc	p.D721A	FBF1_ENST00000389570.4_Missense_Mutation_p.D721A|FBF1_ENST00000319129.5_Missense_Mutation_p.D720A			A6NLR5	A6NLR5_HUMAN	Fas (TNFRSF6) binding factor 1	720										large_intestine(2)|ovary(1)|upper_aerodigestive_tract(1)	4						GACCTCTCGGTCCTTCAGCAG	0.672000													3	10					0	0	1	0	0
ARHGAP39	80728	broad.mit.edu	37	8	145773409	145773409	+	Missense_Mutation	SNP	C	C	T			TCGA-SA-A6C2-01A-11D-A35I-08	TCGA-SA-A6C2-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b3ca65fd-7d56-476d-86c9-8a7d2eab5435	4354bce8-2d8c-4cd4-86c5-f9f7bb0aaf2c	g.chr8:145773409C>T	ENST00000276826.5	-	4	1262	c.1061G>A	c.(1060-1062)cGg>cAg	p.R354Q	ARHGAP39_ENST00000377307.2_Missense_Mutation_p.R354Q|ARHGAP39_ENST00000540274.1_Missense_Mutation_p.R354Q			Q9C0H5	RHG39_HUMAN	Rho GTPase activating protein 39	354	Pro-rich.				axon guidance|regulation of small GTPase mediated signal transduction|small GTPase mediated signal transduction	cytoskeleton|cytosol|nucleus	GTPase activator activity			NS(1)|endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|lung(11)|prostate(1)|skin(2)|upper_aerodigestive_tract(1)|urinary_tract(3)	22						GAGGAACGGCCGGGGCTTACG	0.697000													8	7					0	0	1	0	0
RSG1	79363	broad.mit.edu	37	1	16558644	16558644	+	Missense_Mutation	SNP	C	C	G			TCGA-SA-A6C2-01A-11D-A35I-08	TCGA-SA-A6C2-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b3ca65fd-7d56-476d-86c9-8a7d2eab5435	4354bce8-2d8c-4cd4-86c5-f9f7bb0aaf2c	g.chr1:16558644C>G	ENST00000375599.3	-	5	1095	c.676G>C	c.(676-678)Gac>Cac	p.D226H		NM_030907.3	NP_112169.2	Q9BU20	RSG1_HUMAN	REM2 and RAB-like small GTPase 1	226	Small GTPase-like.				cellular protein localization|cilium assembly|exocytosis|protein transport|regulation of exocytosis|regulation of vesicle fusion|small GTPase mediated signal transduction	cilium|microtubule basal body	GTP binding			large_intestine(2)|lung(2)|pancreas(1)|prostate(1)	6						TGGGCAACGTCGGCCAGCCCA	0.687000													4	27					0	0	1	0	0
AQP7	364	broad.mit.edu	37	9	33385614	33385614	+	Missense_Mutation	SNP	A	A	T	rs140995428	by1000genomes	TCGA-SA-A6C2-01A-11D-A35I-08	TCGA-SA-A6C2-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b3ca65fd-7d56-476d-86c9-8a7d2eab5435	4354bce8-2d8c-4cd4-86c5-f9f7bb0aaf2c	g.chr9:33385614A>T	ENST00000541274.1	-	5	830	c.381T>A	c.(379-381)agT>agA	p.S127R	AQP7_ENST00000537089.1_3'UTR|AQP7_ENST00000539936.1_3'UTR|AQP7_ENST00000377425.4_Intron			O14520	AQP7_HUMAN	aquaporin 7	0					excretion|generation of precursor metabolites and energy	cell-cell junction|cytoplasm|integral to plasma membrane	glycerol channel activity|water channel activity			NS(1)|large_intestine(1)|lung(7)|ovary(1)|prostate(4)|skin(2)|stomach(1)	17			LUSC - Lung squamous cell carcinoma(29;0.00788)	GBM - Glioblastoma multiforme(74;0.191)		CCACAGAAAAACTCAAAGGAA	0.632000													3	40					0	0	1	0	0
TRIM62	55223	broad.mit.edu	37	1	33612992	33612992	+	Missense_Mutation	SNP	G	G	A			TCGA-SA-A6C2-01A-11D-A35I-08	TCGA-SA-A6C2-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b3ca65fd-7d56-476d-86c9-8a7d2eab5435	4354bce8-2d8c-4cd4-86c5-f9f7bb0aaf2c	g.chr1:33612992G>A	ENST00000291416.5	-	5	1447	c.1214C>T	c.(1213-1215)aCg>aTg	p.T405M	TRIM62_ENST00000543586.1_Missense_Mutation_p.T284M	NM_018207.2	NP_060677.2	Q9BVG3	TRI62_HUMAN	tripartite motif containing 62	405	B30.2/SPRY.					intracellular	zinc ion binding			endometrium(3)|kidney(2)|large_intestine(4)|lung(4)|upper_aerodigestive_tract(1)|urinary_tract(1)	15		Myeloproliferative disorder(586;0.0393)				GTTAAGCCGCGTCCAGGGCTC	0.587000													19	18					0	0	1	0	0
SSX5	6758	broad.mit.edu	37	X	48049618	48049618	+	Silent	SNP	C	C	A			TCGA-SA-A6C2-01A-11D-A35I-08	TCGA-SA-A6C2-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b3ca65fd-7d56-476d-86c9-8a7d2eab5435	4354bce8-2d8c-4cd4-86c5-f9f7bb0aaf2c	g.chrX:48049618C>A	ENST00000311798.1	-	7	592	c.540G>T	c.(538-540)ctG>ctT	p.L180L	SSX5_ENST00000347757.1_Silent_p.L139L|SSX5_ENST00000376923.1_Silent_p.L139L	NM_021015.3	NP_066295.3	O60225	SSX5_HUMAN	synovial sarcoma, X breakpoint 5	139					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	nucleic acid binding			endometrium(3)|kidney(1)|large_intestine(6)|lung(7)|skin(1)	18						CTGAGGGGCGCAGCTGTTTCC	0.463000													7	146					0.0293803	0.0293803	1	1	0
USP32	84669	broad.mit.edu	37	17	58303433	58303433	+	Missense_Mutation	SNP	T	T	C			TCGA-SA-A6C2-01A-11D-A35I-08	TCGA-SA-A6C2-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b3ca65fd-7d56-476d-86c9-8a7d2eab5435	4354bce8-2d8c-4cd4-86c5-f9f7bb0aaf2c	g.chr17:58303433T>C	ENST00000300896.4	-	13	1593	c.1399A>G	c.(1399-1401)Act>Gct	p.T467A	USP32_ENST00000592339.1_Missense_Mutation_p.T137A	NM_032582.3	NP_115971.2	Q8NFA0	UBP32_HUMAN	ubiquitin specific peptidase 32	467	DUSP.				protein deubiquitination|ubiquitin-dependent protein catabolic process	Golgi apparatus|membrane	calcium ion binding|cysteine-type peptidase activity|ubiquitin thiolesterase activity			NS(3)|breast(5)|endometrium(5)|kidney(4)|large_intestine(12)|liver(1)|lung(24)|pancreas(1)|prostate(3)|skin(3)|urinary_tract(1)	62	all_neural(34;0.0878)|Medulloblastoma(34;0.0922)		Epithelial(12;2.02e-11)|all cancers(12;5.23e-10)|Colorectal(3;0.198)			TCAGATGCAGTAGAAATGTTG	0.433000													32	54					0	0	1	0	0
ELFN2	114794	broad.mit.edu	37	22	37769955	37769955	+	Missense_Mutation	SNP	C	C	G			TCGA-SA-A6C2-01A-11D-A35I-08	TCGA-SA-A6C2-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b3ca65fd-7d56-476d-86c9-8a7d2eab5435	4354bce8-2d8c-4cd4-86c5-f9f7bb0aaf2c	g.chr22:37769955C>G	ENST00000402918.1	-	3	2405	c.1620G>C	c.(1618-1620)gaG>gaC	p.E540D	RP1-63G5.5_ENST00000430883.1_RNA|ELFN2_ENST00000349653.3_Missense_Mutation_p.E540D	NM_052906.3	NP_443138.2	Q5R3F8	LRFN6_HUMAN	extracellular leucine-rich repeat and fibronectin type III domain containing 2	540						cell surface|integral to membrane				NS(1)|endometrium(5)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(4)|lung(13)|ovary(1)|prostate(1)|skin(1)|stomach(1)|upper_aerodigestive_tract(3)|urinary_tract(1)	35	Melanoma(58;0.0574)					CCTTGTCCACCTCCTTGGCAA	0.642000													6	76					0	0	1	0	0
ST6GALNAC1	55808	broad.mit.edu	37	17	74621461	74621461	+	Missense_Mutation	SNP	A	A	G			TCGA-SA-A6C2-01A-11D-A35I-08	TCGA-SA-A6C2-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b3ca65fd-7d56-476d-86c9-8a7d2eab5435	4354bce8-2d8c-4cd4-86c5-f9f7bb0aaf2c	g.chr17:74621461A>G	ENST00000156626.7	-	9	1953	c.1754T>C	c.(1753-1755)aTc>aCc	p.I585T		NM_018414.3	NP_060884.1	Q9NSC7	SIA7A_HUMAN	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1	585					protein glycosylation	integral to Golgi membrane	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity			breast(2)|cervix(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(3)|lung(11)|prostate(1)|upper_aerodigestive_tract(1)	22						GTACAGCCGGATTATCCCTTC	0.537000													15	18					0	0	1	0	0
FLG	2312	broad.mit.edu	37	1	152282021	152282021	+	Missense_Mutation	SNP	G	G	A			TCGA-SA-A6C2-01A-11D-A35I-08	TCGA-SA-A6C2-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b3ca65fd-7d56-476d-86c9-8a7d2eab5435	4354bce8-2d8c-4cd4-86c5-f9f7bb0aaf2c	g.chr1:152282021G>A	ENST00000368799.1	-	3	5376	c.5341C>T	c.(5341-5343)Cgc>Tgc	p.R1781C	FLG-AS1_ENST00000420707.1_RNA|FLG-AS1_ENST00000593011.1_RNA	NM_002016.1	NP_002007.1	P20930	FILA_HUMAN	filaggrin	1781	Ser-rich.				keratinocyte differentiation	cytoplasmic membrane-bounded vesicle|intermediate filament	calcium ion binding|structural molecule activity	p.R1781C(1)		autonomic_ganglia(1)|breast(13)|central_nervous_system(5)|cervix(2)|endometrium(38)|haematopoietic_and_lymphoid_tissue(1)|kidney(16)|large_intestine(57)|lung(211)|ovary(13)|pancreas(1)|prostate(15)|skin(24)|stomach(5)|upper_aerodigestive_tract(10)|urinary_tract(12)	424	Hepatocellular(266;0.0877)|Melanoma(130;0.116)|all_hematologic(923;0.127)		LUSC - Lung squamous cell carcinoma(543;0.206)			GGCCCTGTGCGTCCATGGGCG	0.602000									Ichthyosis				5	196					0	0	1	0	0
CA2	760	broad.mit.edu	37	8	86389491	86389491	+	Missense_Mutation	SNP	T	T	A			TCGA-SA-A6C2-01A-11D-A35I-08	TCGA-SA-A6C2-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b3ca65fd-7d56-476d-86c9-8a7d2eab5435	4354bce8-2d8c-4cd4-86c5-f9f7bb0aaf2c	g.chr8:86389491T>A	ENST00000285379.5	+	6	880	c.650T>A	c.(649-651)gTc>gAc	p.V217D		NM_000067.2	NP_000058.1	P00918	CAH2_HUMAN	carbonic anhydrase II	217					one-carbon metabolic process	apical part of cell	carbonate dehydratase activity|zinc ion binding			central_nervous_system(2)|cervix(1)|large_intestine(2)|lung(5)|prostate(1)	11					Acetazolamide(DB00819)|Bendroflumethiazide(DB00436)|Benzthiazide(DB00562)|Brinzolamide(DB01194)|Chlorothiazide(DB00880)|Cyclothiazide(DB00606)|Diazoxide(DB01119)|Dorzolamide(DB00869)|Ethinamate(DB01031)|Hydrochlorothiazide(DB00999)|Hydroflumethiazide(DB00774)|Methyclothiazide(DB00232)|Quinethazone(DB01325)|Topiramate(DB00273)|Trichlormethiazide(DB01021)	CCCATCAGCGTCAGCAGCGAG	0.517000													59	80					0	0	1	0	0
HLA-V	352962	broad.mit.edu	37	6	29760353	29760373	+	RNA	DEL	GCGGGCGCCGTGGATGGAGCA	GCGGGCGCCGTGGATGGAGCA	-	rs74661005	by1000genomes	TCGA-SA-A6C2-01A-11D-A35I-08	TCGA-SA-A6C2-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b3ca65fd-7d56-476d-86c9-8a7d2eab5435	4354bce8-2d8c-4cd4-86c5-f9f7bb0aaf2c	g.chr6:29760353_29760373delGCGGGCGCCGTGGATGGAGCA	ENST00000457107.1	+	0	223_243																											GGATGGAGCCGCGGGCGCCGTGGATGGAGCAGGAGGGGCCG	0.674													4	2	---	---	---	---					
TMEM120A	83862	broad.mit.edu	37	7	75616893	75616893	+	RNA	DEL	C	C	-			TCGA-SA-A6C2-01A-11D-A35I-08	TCGA-SA-A6C2-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b3ca65fd-7d56-476d-86c9-8a7d2eab5435	4354bce8-2d8c-4cd4-86c5-f9f7bb0aaf2c	g.chr7:75616893delC	ENST00000493111.2	-	0	811				TMEM120A_ENST00000338761.4_RNA			Q9BXJ8	T120A_HUMAN	transmembrane protein 120A							integral to membrane											GAAGGTGAGGCCCCGCCACAT	0.632													2	4	---	---	---	---					
ACER2	340485	broad.mit.edu	37	9	19446412	19446412	+	Frame_Shift_Del	DEL	A	A	-			TCGA-SA-A6C2-01A-11D-A35I-08	TCGA-SA-A6C2-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b3ca65fd-7d56-476d-86c9-8a7d2eab5435	4354bce8-2d8c-4cd4-86c5-f9f7bb0aaf2c	g.chr9:19446412delA	ENST00000340967.2	+	5	663	c.637delA	c.(637-639)tgfs	p.M213fs		NM_001010887.2	NP_001010887.2	Q5QJU3	ACER2_HUMAN	alkaline ceramidase 2	213					ceramide metabolic process|negative regulation of cell adhesion mediated by integrin|negative regulation of cell-matrix adhesion|negative regulation of protein glycosylation in Golgi|positive regulation of cell proliferation|response to retinoic acid|sphingosine biosynthetic process	integral to Golgi membrane	ceramidase activity			endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(2)|lung(6)|prostate(1)|skin(1)	13						CCTGCACTGCATGTGGTAAGC	0.592													8	85	---	---	---	---					
SYT16	83851	broad.mit.edu	37	14	62542092	62542093	+	Frame_Shift_Ins	INS	-	-	C			TCGA-SA-A6C2-01A-11D-A35I-08	TCGA-SA-A6C2-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b3ca65fd-7d56-476d-86c9-8a7d2eab5435	4354bce8-2d8c-4cd4-86c5-f9f7bb0aaf2c	g.chr14:62542092_62542093insC	ENST00000430451.2	+	3	1173_1174	c.976_977insC	c.(976-978)catfs	p.H326fs	RP11-355I22.5_ENST00000553990.1_lincRNA|SYT16_ENST00000446982.2_Frame_Shift_Ins_p.H326fs	NM_031914.2	NP_114120.2	Q17RD7	SYT16_HUMAN	synaptotagmin XVI	326										central_nervous_system(1)|endometrium(3)|kidney(1)|large_intestine(11)|lung(12)|prostate(2)|skin(2)|stomach(1)|upper_aerodigestive_tract(2)	35				OV - Ovarian serous cystadenocarcinoma(108;0.0438)|BRCA - Breast invasive adenocarcinoma(234;0.118)		TGACAGCTCCTCCATGTGGAGT	0.475													57	50	---	---	---	---					
BRD7	29117	broad.mit.edu	37	16	50357568	50357571	+	Frame_Shift_Del	DEL	ACAT	ACAT	-	rs78557784	byFrequency	TCGA-SA-A6C2-01A-11D-A35I-08	TCGA-SA-A6C2-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b3ca65fd-7d56-476d-86c9-8a7d2eab5435	4354bce8-2d8c-4cd4-86c5-f9f7bb0aaf2c	g.chr16:50357568_50357571delACAT	ENST00000394688.3	-	12	1529_1532	c.1370_1373delATGT	c.(1369-1374)tcfs	p.YV457fs	BRD7_ENST00000394689.2_Frame_Shift_Del_p.YV457fs			Q9NPI1	BRD7_HUMAN	bromodomain containing 7	457					cell cycle|negative regulation of cell proliferation|negative regulation of G1/S transition of mitotic cell cycle|negative regulation of transcription, DNA-dependent|positive regulation of histone acetylation|positive regulation of transcription, DNA-dependent|regulation of transcription from RNA polymerase II promoter|transcription, DNA-dependent|Wnt receptor signaling pathway	cytoplasm|nucleus	histone acetyl-lysine binding|p53 binding|transcription coactivator activity|transcription corepressor activity|transcription factor binding|transcription regulatory region DNA binding			autonomic_ganglia(1)|breast(2)|endometrium(2)|kidney(2)|large_intestine(4)|lung(7)|prostate(2)|urinary_tract(2)	22		all_cancers(37;0.0127)				ATCTGCCATGACATACGGATAATC	0.436													7	127	---	---	---	---					
FLII	2314	broad.mit.edu	37	17	18161946	18161946	+	Frame_Shift_Del	DEL	A	A	-			TCGA-SA-A6C2-01A-11D-A35I-08	TCGA-SA-A6C2-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b3ca65fd-7d56-476d-86c9-8a7d2eab5435	4354bce8-2d8c-4cd4-86c5-f9f7bb0aaf2c	g.chr17:18161946delA	ENST00000327031.4	-	1	284	c.59delT	c.(58-60)tcfs	p.F20fs	FLII_ENST00000545457.2_Frame_Shift_Del_p.F20fs|FLII_ENST00000379450.4_5'UTR|FLII_ENST00000578558.1_Frame_Shift_Del_p.F20fs|FLII_ENST00000584444.1_5'UTR	NM_002018.3	NP_002009.1	Q13045	FLII_HUMAN	flightless I homolog (Drosophila)	20	Interaction with LRRFIP1 and LRRFIP2.				multicellular organismal development|muscle contraction|regulation of transcription, DNA-dependent|transcription, DNA-dependent	centrosome|nucleus	actin binding			central_nervous_system(2)|endometrium(5)|kidney(1)|large_intestine(6)|lung(11)|ovary(2)|prostate(2)|skin(2)|upper_aerodigestive_tract(1)	32	all_neural(463;0.228)					GCTCACCTTGAAGTCGTTGCC	0.761													2	4	---	---	---	---