Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
GPR128	84873	broad.mit.edu	37	3	100362211	100362211	+	Missense_Mutation	SNP	C	C	T			TCGA-W2-A7H7-01A-11D-A35I-08	TCGA-W2-A7H7-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b59ab157-a667-49fc-a867-4f0a9f5a3df9	17d4339d-169d-4808-92ec-5e95778c4b99	g.chr3:100362211C>T	ENST00000273352.3	+	7	1068	c.800C>T	c.(799-801)gCg>gTg	p.A267V	GPR128_ENST00000475887.1_Intron	NM_032787.2	NP_116176.2	Q96K78	GP128_HUMAN	G protein-coupled receptor 128	267					neuropeptide signaling pathway	integral to membrane|plasma membrane	G-protein coupled receptor activity			NS(1)|autonomic_ganglia(1)|breast(2)|cervix(1)|endometrium(3)|kidney(2)|large_intestine(9)|liver(2)|lung(20)|ovary(3)|prostate(2)|skin(3)|stomach(1)|upper_aerodigestive_tract(4)|urinary_tract(2)	56						TCAGAAAATGCGGTGGGGCCT	0.403000													4	130					0	0	1	0	0
CHD5	26038	broad.mit.edu	37	1	6202616	6202616	+	Missense_Mutation	SNP	C	C	T			TCGA-W2-A7H7-01A-11D-A35I-08	TCGA-W2-A7H7-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b59ab157-a667-49fc-a867-4f0a9f5a3df9	17d4339d-169d-4808-92ec-5e95778c4b99	g.chr1:6202616C>T	ENST00000262450.3	-	14	2192	c.2093G>A	c.(2092-2094)gGc>gAc	p.G698D	CHD5_ENST00000378021.1_5'UTR	NM_015557.2	NP_056372.1	Q8TDI0	CHD5_HUMAN	chromodomain helicase DNA binding protein 5	698					chromatin modification|regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	ATP binding|ATP-dependent helicase activity|DNA binding|zinc ion binding			breast(3)|central_nervous_system(3)|liver(1)|lung(1)|ovary(4)|pancreas(1)|skin(1)|upper_aerodigestive_tract(2)	16	Ovarian(185;0.0634)	all_cancers(23;5.36e-32)|all_epithelial(116;2.32e-17)|all_neural(13;3.68e-06)|all_lung(118;3.94e-06)|all_hematologic(16;2.39e-05)|Lung NSC(185;5.33e-05)|Acute lymphoblastic leukemia(12;0.000372)|Glioma(11;0.00127)|Renal(390;0.00188)|Colorectal(325;0.00342)|Breast(487;0.00373)|Hepatocellular(190;0.0218)|Myeloproliferative disorder(586;0.0393)|Ovarian(437;0.15)		Epithelial(90;3.08e-37)|GBM - Glioblastoma multiforme(13;1.36e-31)|OV - Ovarian serous cystadenocarcinoma(86;7.7e-19)|Colorectal(212;9.97e-08)|COAD - Colon adenocarcinoma(227;1.07e-05)|Kidney(185;6.16e-05)|KIRC - Kidney renal clear cell carcinoma(229;0.00109)|BRCA - Breast invasive adenocarcinoma(365;0.0012)|STAD - Stomach adenocarcinoma(132;0.00346)|READ - Rectum adenocarcinoma(331;0.0649)|Lung(427;0.193)		GTGCAGTGTGCCGCCTGTGGA	0.642000													4	54					0	0	1	0	0
DYRK2	8445	broad.mit.edu	37	12	68051587	68051587	+	Silent	SNP	G	G	A			TCGA-W2-A7H7-01A-11D-A35I-08	TCGA-W2-A7H7-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b59ab157-a667-49fc-a867-4f0a9f5a3df9	17d4339d-169d-4808-92ec-5e95778c4b99	g.chr12:68051587G>A	ENST00000344096.3	+	3	1313	c.900G>A	c.(898-900)acG>acA	p.T300T	DYRK2_ENST00000393555.3_Silent_p.T227T	NM_006482.2	NP_006473.2	Q92630	DYRK2_HUMAN	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2	300	Protein kinase.				apoptosis|DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis|positive regulation of glycogen biosynthetic process|smoothened signaling pathway	cytoplasm|nucleus	ATP binding|magnesium ion binding|manganese ion binding|protein serine/threonine kinase activity|protein tyrosine kinase activity			breast(2)|central_nervous_system(1)|endometrium(6)|kidney(2)|large_intestine(7)|lung(6)|ovary(2)|prostate(2)|skin(1)|urinary_tract(1)	30			Lung(24;6.81e-05)|LUAD - Lung adenocarcinoma(15;0.00107)|LUSC - Lung squamous cell carcinoma(43;0.196)	GBM - Glioblastoma multiforme(7;0.000573)		TCTGCATGACGTTTGAGCTGC	0.478000													4	159					0	0	1	0	0
GPC5	2262	broad.mit.edu	37	13	92346010	92346010	+	Silent	SNP	T	T	C			TCGA-W2-A7H7-01A-11D-A35I-08	TCGA-W2-A7H7-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b59ab157-a667-49fc-a867-4f0a9f5a3df9	17d4339d-169d-4808-92ec-5e95778c4b99	g.chr13:92346010T>C	ENST00000377067.3	+	3	1267	c.895T>C	c.(895-897)Ttg>Ctg	p.L299L		NM_004466.4	NP_004457.1	P78333	GPC5_HUMAN	glypican 5	299						anchored to membrane|extracellular space|integral to plasma membrane|proteinaceous extracellular matrix	heparan sulfate proteoglycan binding			NS(1)|breast(4)|endometrium(6)|kidney(4)|large_intestine(7)|lung(34)|ovary(2)|pancreas(1)|prostate(2)|skin(5)|upper_aerodigestive_tract(2)|urinary_tract(1)	69	all_cancers(3;1.43e-07)|all_neural(89;0.0804)|Medulloblastoma(90;0.163)	Lung NSC(4;0.00454)				TATCCGGTCGTTGGAAGAACT	0.502000													11	77					0	0	1	0	0
COL6A6	131873	broad.mit.edu	37	3	130282279	130282279	+	Silent	SNP	G	G	A			TCGA-W2-A7H7-01A-11D-A35I-08	TCGA-W2-A7H7-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b59ab157-a667-49fc-a867-4f0a9f5a3df9	17d4339d-169d-4808-92ec-5e95778c4b99	g.chr3:130282279G>A	ENST00000358511.6	+	2	463	c.432G>A	c.(430-432)gaG>gaA	p.E144E	COL6A6_ENST00000453409.2_Silent_p.E144E	NM_001102608.1	NP_001096078.1	A6NMZ7	CO6A6_HUMAN	collagen, type VI, alpha 6	144	Nonhelical region.|VWFA 1.				axon guidance|cell adhesion	collagen				NS(2)|breast(5)|central_nervous_system(1)|endometrium(8)|haematopoietic_and_lymphoid_tissue(1)|kidney(10)|large_intestine(30)|lung(57)|ovary(8)|pancreas(1)|prostate(2)|skin(1)|stomach(1)|upper_aerodigestive_tract(5)|urinary_tract(2)	134						CTGAGTCTGAGGATAATGTGG	0.498000													18	10					0	0	1	0	0
GON4L	54856	broad.mit.edu	37	1	155723052	155723052	+	Nonsense_Mutation	SNP	C	C	A			TCGA-W2-A7H7-01A-11D-A35I-08	TCGA-W2-A7H7-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b59ab157-a667-49fc-a867-4f0a9f5a3df9	17d4339d-169d-4808-92ec-5e95778c4b99	g.chr1:155723052C>A	ENST00000437809.1	-	29	5907	c.5785G>T	c.(5785-5787)Gag>Tag	p.E1929*	GON4L_ENST00000368331.1_Nonsense_Mutation_p.E1929*|GON4L_ENST00000271883.5_Nonsense_Mutation_p.E1929*			Q3T8J9	GON4L_HUMAN	gon-4-like (C. elegans)	1929					regulation of transcription, DNA-dependent	cytoplasm|nucleus	DNA binding			NS(2)|breast(4)|cervix(1)|endometrium(7)|kidney(4)|large_intestine(7)|lung(10)|ovary(3)|prostate(3)|skin(2)|stomach(1)|urinary_tract(1)	45	Hepatocellular(266;0.0997)|all_hematologic(923;0.145)|all_neural(408;0.195)					TGGGTGGCCTCAGTGCTCTCC	0.587000													11	60					3.07112e-06	3.07112e-06	1	1	0
KRTAP1-5	83895	broad.mit.edu	37	17	39183145	39183145	+	Missense_Mutation	SNP	A	A	G			TCGA-W2-A7H7-01A-11D-A35I-08	TCGA-W2-A7H7-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b59ab157-a667-49fc-a867-4f0a9f5a3df9	17d4339d-169d-4808-92ec-5e95778c4b99	g.chr17:39183145A>G	ENST00000361883.5	-	1	309	c.263T>C	c.(262-264)aTc>aCc	p.I88T		NM_031957.1	NP_114163.1	Q9BYS1	KRA15_HUMAN	keratin associated protein 1-5	88	15 X 5 AA repeats of C-C-[QEPVRC]- [TPIVLE]-[SRHVP].					keratin filament		p.I88T(11)		central_nervous_system(1)|endometrium(2)|kidney(1)|lung(9)|pancreas(1)|prostate(1)|upper_aerodigestive_tract(2)	17		Breast(137;0.00043)	STAD - Stomach adenocarcinoma(17;0.000371)			GCAGGAGCTGATCTGGCAGCA	0.632000													4	50					0	0	1	0	0
ATP6V1G3	127124	broad.mit.edu	37	1	198498248	198498248	+	Missense_Mutation	SNP	A	A	G			TCGA-W2-A7H7-01A-11D-A35I-08	TCGA-W2-A7H7-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b59ab157-a667-49fc-a867-4f0a9f5a3df9	17d4339d-169d-4808-92ec-5e95778c4b99	g.chr1:198498248A>G	ENST00000367381.1	-	4	269	c.164T>C	c.(163-165)aTg>aCg	p.M55T	ATP6V1G3_ENST00000367382.1_Missense_Mutation_p.M49T|ATP6V1G3_ENST00000309309.7_3'UTR|ATP6V1G3_ENST00000281087.2_Missense_Mutation_p.M49T|ATP6V1G3_ENST00000489986.1_Missense_Mutation_p.M55T			Q96LB4	VATG3_HUMAN	ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3	49					cellular iron ion homeostasis|insulin receptor signaling pathway|transferrin transport	cytosol|plasma membrane|vacuolar proton-transporting V-type ATPase complex	ATPase binding			central_nervous_system(1)|endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|lung(3)|prostate(1)	7						ATCTCTCTGCATTCTGTACTG	0.313000													4	34					0	0	1	0	0
SLC2A4	6517	broad.mit.edu	37	17	7189833	7189833	+	Missense_Mutation	SNP	G	G	A			TCGA-W2-A7H7-01A-11D-A35I-08	TCGA-W2-A7H7-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b59ab157-a667-49fc-a867-4f0a9f5a3df9	17d4339d-169d-4808-92ec-5e95778c4b99	g.chr17:7189833G>A	ENST00000317370.8	+	11	1683	c.1415G>A	c.(1414-1416)cGa>cAa	p.R472Q		NM_001042.2	NP_001033.1	P14672	GTR4_HUMAN	solute carrier family 2 (facilitated glucose transporter), member 4	472					carbohydrate metabolic process|glucose homeostasis|glucose import	external side of plasma membrane|integral to plasma membrane|perinuclear region of cytoplasm	D-glucose transmembrane transporter activity|protein binding			breast(1)|endometrium(3)|large_intestine(7)|lung(2)|ovary(1)|skin(2)|upper_aerodigestive_tract(1)	17						CCTGAAACTCGAGGCCGGACG	0.537000													5	293					0	0	1	0	0
MIF4GD	57409	broad.mit.edu	37	17	73266262	73266262	+	Silent	SNP	A	A	G			TCGA-W2-A7H7-01A-11D-A35I-08	TCGA-W2-A7H7-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b59ab157-a667-49fc-a867-4f0a9f5a3df9	17d4339d-169d-4808-92ec-5e95778c4b99	g.chr17:73266262A>G	ENST00000577542.1	-	2	277	c.15T>C	c.(13-15)agT>agC	p.S5S	MIF4GD_ENST00000580571.1_Silent_p.S5S|MIF4GD_ENST00000245551.5_Silent_p.S5S|MIF4GD_ENST00000325102.8_Silent_p.S5S|MIF4GD_ENST00000579297.1_Silent_p.S5S|MIF4GD_ENST00000579119.1_Silent_p.S5S|MIF4GD_ENST00000578305.1_Silent_p.S5S			A9UHW6	MI4GD_HUMAN	MIF4G domain containing	5	MIF4G.				regulation of translation|RNA metabolic process	cytoplasm|nucleus	protein C-terminus binding			breast(2)|endometrium(1)|large_intestine(4)|lung(2)|ovary(1)	10	all_cancers(13;1.25e-07)|all_epithelial(9;2.63e-08)|Breast(9;1.06e-07)		all cancers(21;3.02e-07)|Epithelial(20;2.92e-06)			ACTCCTCTCTACTGGGCTCCC	0.587000													4	220					0	0	1	0	0
ALDH7A1	501	broad.mit.edu	37	5	125903982	125903982	+	Silent	SNP	T	T	C			TCGA-W2-A7H7-01A-11D-A35I-08	TCGA-W2-A7H7-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b59ab157-a667-49fc-a867-4f0a9f5a3df9	17d4339d-169d-4808-92ec-5e95778c4b99	g.chr5:125903982T>C	ENST00000409134.3	-	9	1059	c.840A>G	c.(838-840)aaA>aaG	p.K280K	ALDH7A1_ENST00000553117.1_Silent_p.K280K|ALDH7A1_ENST00000447989.2_Silent_p.K307K|ALDH7A1_ENST00000413020.1_5'UTR	NM_001182.4|NM_001201377.1	NP_001173.2|NP_001188306.1	P49419	AL7A1_HUMAN	aldehyde dehydrogenase 7 family, member A1	280					cellular aldehyde metabolic process|lysine catabolic process|sensory perception of sound	cytosol|mitochondrial matrix|nucleus	aldehyde dehydrogenase (NAD) activity|betaine-aldehyde dehydrogenase activity|L-aminoadipate-semialdehyde dehydrogenase activity			endometrium(1)|kidney(4)|large_intestine(4)|lung(5)|ovary(1)|upper_aerodigestive_tract(1)	16		all_cancers(142;0.24)|Prostate(80;0.081)	KIRC - Kidney renal clear cell carcinoma(527;0.0584)|Kidney(363;0.0934)	Epithelial(69;0.0417)|OV - Ovarian serous cystadenocarcinoma(64;0.068)|all cancers(49;0.109)	NADH(DB00157)|Pyridoxine(DB00165)	GGCCCACCTGTTTTCCCACCT	0.488000													30	72					0	0	1	0	0
LPL	4023	broad.mit.edu	37	8	19811698	19811698	+	Silent	SNP	A	A	G			TCGA-W2-A7H7-01A-11D-A35I-08	TCGA-W2-A7H7-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b59ab157-a667-49fc-a867-4f0a9f5a3df9	17d4339d-169d-4808-92ec-5e95778c4b99	g.chr8:19811698A>G	ENST00000311322.8	+	5	1079	c.609A>G	c.(607-609)gcA>gcG	p.A203A		NM_000237.2	NP_000228.1	P06858	LIPL_HUMAN	lipoprotein lipase	203			A -> T (in LPL deficiency; Bethesda; loss of activity and abnormal heparin binding).		fatty acid biosynthetic process|lipoprotein metabolic process|phospholipid metabolic process|positive regulation of cholesterol storage|positive regulation of sequestering of triglyceride|triglyceride catabolic process|triglyceride homeostasis|very-low-density lipoprotein particle remodeling	anchored to membrane|chylomicron|plasma membrane|very-low-density lipoprotein particle	heparin binding|lipoprotein lipase activity|phospholipase activity|receptor binding|triglyceride lipase activity			NS(1)|breast(1)|central_nervous_system(1)|endometrium(6)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(7)|lung(13)|ovary(1)|pancreas(1)|prostate(1)|skin(1)|urinary_tract(1)	36				Colorectal(111;0.0577)|COAD - Colon adenocarcinoma(73;0.216)	Clofibrate(DB00636)|Gemfibrozil(DB01241)|Orlistat(DB01083)	CTGATGATGCAGATTTTGTAG	0.478000													11	76					0	0	1	0	0
ZNF776	284309	broad.mit.edu	37	19	58265270	58265270	+	Missense_Mutation	SNP	C	C	T			TCGA-W2-A7H7-01A-11D-A35I-08	TCGA-W2-A7H7-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b59ab157-a667-49fc-a867-4f0a9f5a3df9	17d4339d-169d-4808-92ec-5e95778c4b99	g.chr19:58265270C>T	ENST00000317178.5	+	3	1035	c.772C>T	c.(772-774)Cgc>Tgc	p.R258C		NM_173632.3	NP_775903.3			zinc finger protein 776											cervix(1)|endometrium(2)|kidney(13)|large_intestine(3)|lung(7)|ovary(2)|skin(2)|upper_aerodigestive_tract(1)	31		Colorectal(82;0.000256)|all_neural(62;0.0577)|Breast(46;0.147)|Ovarian(87;0.156)		UCEC - Uterine corpus endometrioid carcinoma (67;0.168)|GBM - Glioblastoma multiforme(193;0.0256)		TCAGGGAGTTCGCACTGGAAA	0.423000													6	61					0	0	1	0	0
TUBA8	51807	broad.mit.edu	37	22	18609712	18609712	+	Missense_Mutation	SNP	G	G	T	rs151102020	by1000genomes	TCGA-W2-A7H7-01A-11D-A35I-08	TCGA-W2-A7H7-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b59ab157-a667-49fc-a867-4f0a9f5a3df9	17d4339d-169d-4808-92ec-5e95778c4b99	g.chr22:18609712G>T	ENST00000330423.3	+	4	1040	c.967G>T	c.(967-969)Gtg>Ttg	p.V323L	TUBA8_ENST00000316027.6_Missense_Mutation_p.V257L	NM_018943.2	NP_061816.1	Q9NY65	TBA8_HUMAN	tubulin, alpha 8	323					microtubule-based movement|protein polymerization	cytoplasm|microtubule	GTP binding|GTPase activity|structural molecule activity			breast(1)|cervix(1)|endometrium(2)|kidney(1)|large_intestine(3)|lung(5)|prostate(1)	14						CCGGGGCGACGTGGTGCCCAA	0.557000													22	78					1.40151e-16	1.44984e-16	1	1	0
RRN3P1	730092	broad.mit.edu	37	16	21817457	21817457	+	RNA	SNP	G	G	A	rs150520281	by1000genomes	TCGA-W2-A7H7-01A-11D-A35I-08	TCGA-W2-A7H7-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b59ab157-a667-49fc-a867-4f0a9f5a3df9	17d4339d-169d-4808-92ec-5e95778c4b99	g.chr16:21817457G>A	ENST00000546471.1	-	0	1601																											CTTACATCCAGCTTGAGTAGT	0.259000													6	46					0	0	1	0	0
CENPB	1059	broad.mit.edu	37	20	3765453	3765453	+	Missense_Mutation	SNP	A	A	T			TCGA-W2-A7H7-01A-11D-A35I-08	TCGA-W2-A7H7-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b59ab157-a667-49fc-a867-4f0a9f5a3df9	17d4339d-169d-4808-92ec-5e95778c4b99	g.chr20:3765453A>T	ENST00000379751.4	-	1	1884	c.1678T>A	c.(1678-1680)Tcc>Acc	p.S560T		NM_001810.5	NP_001801.1	P07199	CENPB_HUMAN	centromere protein B, 80kDa	560					regulation of transcription, DNA-dependent	chromosome, centromeric region|nucleus	chromatin binding|satellite DNA binding			kidney(1)|large_intestine(2)|lung(4)|skin(1)	8						ATGGGGAAGGAGGTCAGGTAC	0.562000													5	37					0	0	1	0	0
KRTAP4-7	100132476	broad.mit.edu	37	17	39240661	39240661	+	Missense_Mutation	SNP	C	C	G	rs11650484	by1000genomes	TCGA-W2-A7H7-01A-11D-A35I-08	TCGA-W2-A7H7-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b59ab157-a667-49fc-a867-4f0a9f5a3df9	17d4339d-169d-4808-92ec-5e95778c4b99	g.chr17:39240661C>G	ENST00000391417.4	+	1	203	c.203C>G	c.(202-204)aCc>aGc	p.T68S		NM_033061.3	NP_149050.3			keratin associated protein 4-7											NS(1)|endometrium(3)|kidney(1)|lung(1)|prostate(2)|urinary_tract(1)	9						TGTCGCCCCACCTGCTGTGAG	0.657000													3	70					0	0	1	0	0
KDM4B	23030	broad.mit.edu	37	19	5144146	5144146	+	Missense_Mutation	SNP	A	A	G			TCGA-W2-A7H7-01A-11D-A35I-08	TCGA-W2-A7H7-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b59ab157-a667-49fc-a867-4f0a9f5a3df9	17d4339d-169d-4808-92ec-5e95778c4b99	g.chr19:5144146A>G	ENST00000159111.4	+	19	2937	c.2719A>G	c.(2719-2721)Aag>Gag	p.K907E	KDM4B_ENST00000536461.1_Missense_Mutation_p.K941E	NM_015015.2	NP_055830.1	O94953	KDM4B_HUMAN	lysine (K)-specific demethylase 4B	907					chromatin modification|regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	nucleic acid binding|oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen|zinc ion binding			breast(2)|cervix(1)|endometrium(6)|kidney(1)|large_intestine(1)|liver(1)|lung(14)|prostate(1)|skin(4)|upper_aerodigestive_tract(1)	32						CCTCAAGCACAAGTCGGGGGG	0.711000													22	37					0	0	1	0	0
ZFC3H1	196441	broad.mit.edu	37	12	72057258	72057258	+	Missense_Mutation	SNP	T	T	C			TCGA-W2-A7H7-01A-11D-A35I-08	TCGA-W2-A7H7-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b59ab157-a667-49fc-a867-4f0a9f5a3df9	17d4339d-169d-4808-92ec-5e95778c4b99	g.chr12:72057258T>C	ENST00000378743.3	-	1	491	c.133A>G	c.(133-135)Agc>Ggc	p.S45G	ZFC3H1_ENST00000548100.1_Missense_Mutation_p.S45G|THAP2_ENST00000308086.2_5'UTR|ZFC3H1_ENST00000552037.1_Missense_Mutation_p.S45G	NM_144982.4	NP_659419.3	O60293	ZC3H1_HUMAN	zinc finger, C3H1-type containing	45	Ser-rich.				RNA processing	intracellular	metal ion binding			NS(1)|breast(2)|central_nervous_system(1)|cervix(2)|endometrium(5)|kidney(4)|large_intestine(12)|lung(31)|ovary(3)|prostate(2)|skin(2)|upper_aerodigestive_tract(2)|urinary_tract(2)	69						CCGCCGCCGCTGCTGCTGCTG	0.637000											OREG0021993	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	4	132					0	0	1	0	0
JADE1	79960	broad.mit.edu	37	4	129778604	129778604	+	Missense_Mutation	SNP	A	A	G			TCGA-W2-A7H7-01A-11D-A35I-08	TCGA-W2-A7H7-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b59ab157-a667-49fc-a867-4f0a9f5a3df9	17d4339d-169d-4808-92ec-5e95778c4b99	g.chr4:129778604A>G	ENST00000226319.6	+	8	1256	c.976A>G	c.(976-978)Ata>Gta	p.I326V	PHF17_ENST00000512960.1_Missense_Mutation_p.I326V|PHF17_ENST00000452328.2_Missense_Mutation_p.I314V|PHF17_ENST00000413543.2_Missense_Mutation_p.I326V|PHF17_ENST00000511647.1_Missense_Mutation_p.I326V	NM_199320.2	NP_955352.1	Q6IE81	JADE1_HUMAN		326					apoptosis|histone H3 acetylation|histone H4-K12 acetylation|histone H4-K5 acetylation|histone H4-K8 acetylation|negative regulation of cell growth|regulation of transcription, DNA-dependent|response to stress|transcription, DNA-dependent	histone acetyltransferase complex|mitochondrion	protein binding|zinc ion binding			NS(1)|breast(2)|endometrium(1)|kidney(2)|large_intestine(10)|lung(10)|prostate(1)|skin(1)|upper_aerodigestive_tract(1)	29						TGGGGCCTCTATACAGGTAAT	0.537000													66	107					0	0	1	0	0
MLLT6	4302	broad.mit.edu	37	17	36871916	36871916	+	Missense_Mutation	SNP	A	A	T			TCGA-W2-A7H7-01A-11D-A35I-08	TCGA-W2-A7H7-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b59ab157-a667-49fc-a867-4f0a9f5a3df9	17d4339d-169d-4808-92ec-5e95778c4b99	g.chr17:36871916A>T	ENST00000325718.7	+	9	962	c.871A>T	c.(871-873)Acc>Tcc	p.T291S	CTB-58E17.9_ENST00000579499.1_RNA	NM_005937.3	NP_005928.2	P55198	AF17_HUMAN	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6	291					regulation of transcription, DNA-dependent	nucleus	protein binding|zinc ion binding			breast(3)|lung(1)|prostate(1)|skin(2)|upper_aerodigestive_tract(1)	8	Breast(7;4.43e-21)					CACGCAGGAGACCTCTGAGAG	0.562000			T	MLL	AL								3	25					0	0	1	0	0
NOA1	84273	broad.mit.edu	37	4	57832876	57832876	+	Silent	SNP	G	G	A			TCGA-W2-A7H7-01A-11D-A35I-08	TCGA-W2-A7H7-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b59ab157-a667-49fc-a867-4f0a9f5a3df9	17d4339d-169d-4808-92ec-5e95778c4b99	g.chr4:57832876G>A	ENST00000264230.4	-	5	2911	c.1674C>T	c.(1672-1674)gtC>gtT	p.V558V		NM_032313.2	NP_115689.1	Q8NC60	CD014_HUMAN	nitric oxide associated 1	558							GTP binding										TGGAAGCCACGACTGTAAACC	0.453000													26	41					0	0	1	0	0
ZNRD1-AS1	80862	broad.mit.edu	37	6	29977342	29977342	+	RNA	SNP	A	A	T	rs116382006	by1000genomes	TCGA-W2-A7H7-01A-11D-A35I-08	TCGA-W2-A7H7-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b59ab157-a667-49fc-a867-4f0a9f5a3df9	17d4339d-169d-4808-92ec-5e95778c4b99	g.chr6:29977342A>T	ENST00000376797.3	-	0	731				HLA-J_ENST00000462773.1_RNA|ZNRD1-AS1_ENST00000420251.1_RNA|ZNRD1-AS1_ENST00000425604.1_RNA|ZNRD1-AS1_ENST00000448093.1_RNA																							TGGGACTGAGAGGCAAGATTT	0.438000													4	52					0	0	1	0	0
CDC20B	166979	broad.mit.edu	37	5	54420759	54420759	+	Missense_Mutation	SNP	A	A	G			TCGA-W2-A7H7-01A-11D-A35I-08	TCGA-W2-A7H7-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b59ab157-a667-49fc-a867-4f0a9f5a3df9	17d4339d-169d-4808-92ec-5e95778c4b99	g.chr5:54420759A>G	ENST00000296733.1	-	9	1261	c.1087T>C	c.(1087-1089)Tgg>Cgg	p.W363R	CDC20B_ENST00000322374.6_Missense_Mutation_p.W363R|CDC20B_ENST00000334206.5_3'UTR|CDC20B_ENST00000381375.2_Missense_Mutation_p.W363R	NM_001170402.1|NM_152623.2	NP_001163873.1|NP_689836.2	Q86Y33	CD20B_HUMAN	cell division cycle 20B	363										kidney(1)|large_intestine(5)|lung(7)|skin(2)|stomach(3)|upper_aerodigestive_tract(1)	19		Lung NSC(810;0.000744)|Breast(144;0.159)|Prostate(74;0.194)	LUSC - Lung squamous cell carcinoma(15;0.225)			TCCGGTGACCACTTCAGAGCA	0.572000													6	114					0	0	1	0	0
MUC7	4589	broad.mit.edu	37	4	71346978	71346978	+	Missense_Mutation	SNP	T	T	C			TCGA-W2-A7H7-01A-11D-A35I-08	TCGA-W2-A7H7-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b59ab157-a667-49fc-a867-4f0a9f5a3df9	17d4339d-169d-4808-92ec-5e95778c4b99	g.chr4:71346978T>C	ENST00000413702.1	+	4	805	c.517T>C	c.(517-519)Tct>Cct	p.S173P	MUC7_ENST00000456088.1_Missense_Mutation_p.S173P|MUC7_ENST00000304887.5_Missense_Mutation_p.S173P|MUC7_ENST00000514512.1_3'UTR	NM_001145006.1	NP_001138478.1	Q8TAX7	MUC7_HUMAN	mucin 7, secreted	173	Thr-rich.					extracellular region	protein binding	p.S173P(3)		central_nervous_system(1)|endometrium(3)|kidney(5)|large_intestine(2)|lung(23)|ovary(3)|skin(3)|upper_aerodigestive_tract(1)|urinary_tract(1)	42			Lung(101;0.211)			ACCCACACCTTCTGCAACTAC	0.522000													4	99					0	0	1	0	0
SREBF2	6721	broad.mit.edu	37	22	42262949	42262951	+	In_Frame_Del	DEL	GCA	GCA	-			TCGA-W2-A7H7-01A-11D-A35I-08	TCGA-W2-A7H7-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b59ab157-a667-49fc-a867-4f0a9f5a3df9	17d4339d-169d-4808-92ec-5e95778c4b99	g.chr22:42262949_42262951delGCA	ENST00000361204.4	+	2	369_371	c.203_205delGCA	c.(202-207)ggc>g	p.GS68del		NM_004599.2	NP_004590.2	Q12772	SRBP2_HUMAN	sterol regulatory element binding transcription factor 2	68	Gly/Pro/Ser-rich.				cholesterol metabolic process	ER to Golgi transport vesicle membrane|Golgi membrane|nucleus|SREBP-SCAP-Insig complex	protein C-terminus binding			NS(2)|breast(6)|central_nervous_system(1)|endometrium(4)|kidney(2)|large_intestine(5)|lung(9)|ovary(1)|pancreas(1)|prostate(2)|skin(2)|upper_aerodigestive_tract(2)|urinary_tract(1)	38						ggcagcagtggcagcagcagcag	0.567													7	118	---	---	---	---