Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
FRG1BP	284802	broad.mit.edu	37	20	29628236	29628236	+	Missense_Mutation	SNP	G	G	C	rs145412486	by1000genomes	TCGA-WB-A81Q-01A-11D-A35I-08	TCGA-WB-A81Q-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2be35d9d-a4ba-438f-b5b7-f6187fa78554	68f9891f-65a7-48ae-95c6-e807a953400b	g.chr20:29628236G>C	ENST00000278882.3	+	6	618	c.238G>C	c.(238-240)Gct>Cct	p.A80P	FRG1B_ENST00000439954.2_Missense_Mutation_p.A85P|FRG1B_ENST00000358464.4_Missense_Mutation_p.A80P														p.A80P(8)		endometrium(10)|kidney(21)|lung(3)|pancreas(1)|prostate(9)|urinary_tract(9)	53						GGGGAAAATGGCTTTGTTGGC	0.363000													6	142					0	0	1	0	0
SETD2	29072	broad.mit.edu	37	3	47158161	47158161	+	Missense_Mutation	SNP	T	T	A			TCGA-WB-A81Q-01A-11D-A35I-08	TCGA-WB-A81Q-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2be35d9d-a4ba-438f-b5b7-f6187fa78554	68f9891f-65a7-48ae-95c6-e807a953400b	g.chr3:47158161T>A	ENST00000409792.3	-	4	4580	c.4538A>T	c.(4537-4539)gAa>gTa	p.E1513V		NM_014159.6	NP_054878.5	Q9BYW2	SETD2_HUMAN	SET domain containing 2	1513	AWS.				regulation of transcription, DNA-dependent|transcription, DNA-dependent	chromosome|nucleus	DNA binding|histone-lysine N-methyltransferase activity|oxidoreductase activity|transition metal ion binding			breast(6)|central_nervous_system(5)|endometrium(4)|kidney(63)|large_intestine(18)|lung(26)|ovary(6)|prostate(2)|skin(3)|soft_tissue(1)|stomach(2)|urinary_tract(5)	141		Acute lymphoblastic leukemia(5;0.0169)		BRCA - Breast invasive adenocarcinoma(193;0.000302)|KIRC - Kidney renal clear cell carcinoma(197;0.00732)|Kidney(197;0.00844)		ACATGCTATTTCACCTTGAGC	0.353000			"""N, F, S, Mis"""		clear cell renal carcinoma								7	144					0	0	1	0	0
BTN2A3P	54718	broad.mit.edu	37	6	26422353	26422353	+	RNA	SNP	C	C	T	rs141013110		TCGA-WB-A81Q-01A-11D-A35I-08	TCGA-WB-A81Q-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2be35d9d-a4ba-438f-b5b7-f6187fa78554	68f9891f-65a7-48ae-95c6-e807a953400b	g.chr6:26422353C>T	ENST00000466808.2	+	0	7																		p.P3S(2)									GCTCATGGAACCAGCTGCTGC	0.622000													4	94					0	0	1	0	0
H2AFY	9555	broad.mit.edu	37	5	134705828	134705828	+	Missense_Mutation	SNP	C	C	A			TCGA-WB-A81Q-01A-11D-A35I-08	TCGA-WB-A81Q-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2be35d9d-a4ba-438f-b5b7-f6187fa78554	68f9891f-65a7-48ae-95c6-e807a953400b	g.chr5:134705828C>A	ENST00000511689.1	-	3	770	c.177G>T	c.(175-177)gaG>gaT	p.E59D	H2AFY_ENST00000312469.4_Missense_Mutation_p.E59D|H2AFY_ENST00000304332.4_Missense_Mutation_p.E59D|H2AFY_ENST00000510038.1_Missense_Mutation_p.E59D|H2AFY_ENST00000423969.2_Intron	NM_001040158.1|NM_138610.2	NP_001035248.1|NP_613258.2	O75367	H2AY_HUMAN	H2A histone family, member Y	59	Histone H2A.				chromatin modification|dosage compensation|nucleosome assembly	Barr body|nucleosome	DNA binding			endometrium(3)|large_intestine(3)|lung(3)|ovary(1)|urinary_tract(1)	11			KIRC - Kidney renal clear cell carcinoma(527;0.0101)|Kidney(363;0.0233)			GCTCCAGAATCTCCGCTGTGG	0.587000													3	16					0.00909568	0.00976122	1	1	0
SHROOM3	57619	broad.mit.edu	37	4	77661845	77661845	+	Missense_Mutation	SNP	C	C	T			TCGA-WB-A81Q-01A-11D-A35I-08	TCGA-WB-A81Q-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2be35d9d-a4ba-438f-b5b7-f6187fa78554	68f9891f-65a7-48ae-95c6-e807a953400b	g.chr4:77661845C>T	ENST00000296043.6	+	5	3472	c.2519C>T	c.(2518-2520)cCc>cTc	p.P840L		NM_020859.3	NP_065910.3	Q8TF72	SHRM3_HUMAN	shroom family member 3	840					apical protein localization|cell morphogenesis|cellular pigment accumulation|pattern specification process|regulation of cell shape	adherens junction|apical junction complex|apical plasma membrane|cytoplasm|microtubule	actin binding			NS(3)|breast(1)|central_nervous_system(1)|cervix(1)|endometrium(10)|kidney(2)|large_intestine(6)|lung(29)|ovary(1)|skin(5)|upper_aerodigestive_tract(1)	60			Lung(101;0.0903)			TCAGCTGAACCCCTAGGCAAC	0.562000													23	81					0	0	1	0	0
PDS5A	23244	broad.mit.edu	37	4	39924324	39924324	+	Missense_Mutation	SNP	A	A	T			TCGA-WB-A81Q-01A-11D-A35I-08	TCGA-WB-A81Q-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2be35d9d-a4ba-438f-b5b7-f6187fa78554	68f9891f-65a7-48ae-95c6-e807a953400b	g.chr4:39924324A>T	ENST00000303538.8	-	6	1111	c.572T>A	c.(571-573)aTg>aAg	p.M191K	PDS5A_ENST00000503396.1_Missense_Mutation_p.M191K	NM_001100399.1	NP_001093869.1	Q29RF7	PDS5A_HUMAN	PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)	191					cell division|mitosis|negative regulation of DNA replication	chromatin|nucleus	identical protein binding			breast(2)|cervix(1)|endometrium(4)|kidney(4)|large_intestine(9)|lung(14)|prostate(3)|skin(1)|urinary_tract(1)	39						GATAGAACTCATCAAATCTAG	0.333000													3	19					0	0	1	0	0
OR8I2	120586	broad.mit.edu	37	11	55860831	55860831	+	Silent	SNP	A	A	G			TCGA-WB-A81Q-01A-11D-A35I-08	TCGA-WB-A81Q-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2be35d9d-a4ba-438f-b5b7-f6187fa78554	68f9891f-65a7-48ae-95c6-e807a953400b	g.chr11:55860831A>G	ENST00000302124.2	+	1	79	c.48A>G	c.(46-48)ggA>ggG	p.G16G	OR8I2_ENST00000560768.1_Silent_p.G16G			Q8N0Y5	OR8I2_HUMAN	olfactory receptor, family 8, subfamily I, member 2	16					sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			NS(1)|breast(2)|endometrium(16)|haematopoietic_and_lymphoid_tissue(2)|large_intestine(4)|lung(24)|ovary(1)|skin(2)|upper_aerodigestive_tract(1)	53	Esophageal squamous(21;0.00693)					TCCTCTCTGGATTTGCAAATC	0.388000													81	113					0	0	1	0	0
SPHKAP	80309	broad.mit.edu	37	2	228881275	228881275	+	Missense_Mutation	SNP	T	T	C			TCGA-WB-A81Q-01A-11D-A35I-08	TCGA-WB-A81Q-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2be35d9d-a4ba-438f-b5b7-f6187fa78554	68f9891f-65a7-48ae-95c6-e807a953400b	g.chr2:228881275T>C	ENST00000392056.3	-	7	4341	c.4295A>G	c.(4294-4296)gAa>gGa	p.E1432G	SPHKAP_ENST00000344657.5_Missense_Mutation_p.E1432G	NM_001142644.1	NP_001136116.1	Q2M3C7	SPKAP_HUMAN	SPHK1 interactor, AKAP domain containing	1432						cytoplasm	protein binding			NS(5)|breast(5)|central_nervous_system(2)|endometrium(11)|haematopoietic_and_lymphoid_tissue(3)|kidney(12)|large_intestine(25)|lung(86)|ovary(6)|pancreas(1)|prostate(6)|skin(17)|stomach(1)|upper_aerodigestive_tract(4)|urinary_tract(1)	185		Renal(207;0.025)|all_hematologic(139;0.15)|all_lung(227;0.204)|Acute lymphoblastic leukemia(138;0.205)|Esophageal squamous(248;0.23)		Epithelial(121;8.17e-11)|all cancers(144;7.92e-08)|Lung(261;0.0168)|LUSC - Lung squamous cell carcinoma(224;0.0232)		CTGATCTGTTTCAATCTGAAT	0.458000													4	77					0	0	1	0	0
HEBP2	23593	broad.mit.edu	37	6	138726293	138726293	+	Silent	SNP	T	T	C			TCGA-WB-A81Q-01A-11D-A35I-08	TCGA-WB-A81Q-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2be35d9d-a4ba-438f-b5b7-f6187fa78554	68f9891f-65a7-48ae-95c6-e807a953400b	g.chr6:138726293T>C	ENST00000607197.1	+	2	391	c.114T>C	c.(112-114)taT>taC	p.Y38Y	HEBP2_ENST00000448741.1_Silent_p.Y49Y|HEBP2_ENST00000367697.3_Silent_p.Y38Y	NM_014320.2	NP_055135.1	Q9Y5Z4	HEBP2_HUMAN	heme binding protein 2	38						mitochondrion				endometrium(1)|large_intestine(1)|lung(3)	5	Breast(32;0.0933)			GBM - Glioblastoma multiforme(68;0.000732)|OV - Ovarian serous cystadenocarcinoma(155;0.00171)		CCGGAAGTTATGAGATCCGAC	0.507000													59	72					0	0	1	0	0
TAB2	23118	broad.mit.edu	37	6	149718873	149718873	+	Missense_Mutation	SNP	A	A	T			TCGA-WB-A81Q-01A-11D-A35I-08	TCGA-WB-A81Q-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2be35d9d-a4ba-438f-b5b7-f6187fa78554	68f9891f-65a7-48ae-95c6-e807a953400b	g.chr6:149718873A>T	ENST00000367456.1	+	5	2314	c.1737A>T	c.(1735-1737)agA>agT	p.R579S	TAB2_ENST00000286332.5_Missense_Mutation_p.R579S|TAB2_ENST00000538427.1_Missense_Mutation_p.R579S|TAB2_ENST00000536230.1_Missense_Mutation_p.R547S			Q9NYJ8	TAB2_HUMAN	TGF-beta activated kinase 1/MAP3K7 binding protein 2	579					activation of MAPK activity|heart development|I-kappaB kinase/NF-kappaB cascade|innate immune response|JNK cascade|MyD88-dependent toll-like receptor signaling pathway|MyD88-independent toll-like receptor signaling pathway|positive regulation of I-kappaB kinase/NF-kappaB cascade|positive regulation of NF-kappaB transcription factor activity|stress-activated MAPK cascade|T cell receptor signaling pathway|Toll signaling pathway|toll-like receptor 1 signaling pathway|toll-like receptor 2 signaling pathway|toll-like receptor 3 signaling pathway|toll-like receptor 4 signaling pathway	cytosol|endosome membrane|plasma membrane	K63-linked polyubiquitin binding|zinc ion binding			breast(2)|endometrium(6)|kidney(3)|large_intestine(2)|lung(7)|ovary(1)|urinary_tract(1)	22						GCCTGAAAAGATCAAATTCTA	0.343000													5	100					0	0	1	0	0
MMP8	4317	broad.mit.edu	37	11	102584138	102584138	+	Missense_Mutation	SNP	C	C	A			TCGA-WB-A81Q-01A-11D-A35I-08	TCGA-WB-A81Q-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2be35d9d-a4ba-438f-b5b7-f6187fa78554	68f9891f-65a7-48ae-95c6-e807a953400b	g.chr11:102584138C>A	ENST00000236826.3	-	10	1443	c.1345G>T	c.(1345-1347)Gct>Tct	p.A449S		NM_002424.2	NP_002415.1	P22894	MMP8_HUMAN	matrix metallopeptidase 8 (neutrophil collagenase)	449	Hemopexin-like 4.				collagen catabolic process|proteolysis	extracellular space|proteinaceous extracellular matrix	metalloendopeptidase activity|serine-type endopeptidase activity|zinc ion binding			autonomic_ganglia(1)|breast(3)|kidney(1)|large_intestine(4)|lung(11)|ovary(4)|skin(6)|stomach(1)|urinary_tract(1)	32	all_cancers(8;0.00092)|all_epithelial(12;0.00389)|Lung NSC(15;0.227)	all_hematologic(158;0.00092)|Acute lymphoblastic leukemia(157;0.000967)	Epithelial(9;0.0555)|Lung(13;0.0828)|LUSC - Lung squamous cell carcinoma(19;0.151)|all cancers(10;0.189)	BRCA - Breast invasive adenocarcinoma(274;0.0141)		ACTCTCTGAGCAATAAGATCA	0.343000													6	89					0.0293803	0.0307794	1	1	0
VPS8	23355	broad.mit.edu	37	3	184689502	184689502	+	Nonsense_Mutation	SNP	C	C	T			TCGA-WB-A81Q-01A-11D-A35I-08	TCGA-WB-A81Q-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2be35d9d-a4ba-438f-b5b7-f6187fa78554	68f9891f-65a7-48ae-95c6-e807a953400b	g.chr3:184689502C>T	ENST00000437079.3	+	40	3553	c.3382C>T	c.(3382-3384)Cag>Tag	p.Q1128*	VPS8_ENST00000436792.2_Nonsense_Mutation_p.Q1126*|VPS8_ENST00000287546.4_Nonsense_Mutation_p.Q1128*|VPS8_ENST00000446204.2_Nonsense_Mutation_p.Q1036*	NM_001009921.2	NP_001009921.1	Q8N3P4	VPS8_HUMAN	vacuolar protein sorting 8 homolog (S. cerevisiae)	1128							zinc ion binding			NS(1)|breast(1)|central_nervous_system(3)|cervix(1)|endometrium(6)|kidney(4)|large_intestine(11)|lung(19)|ovary(1)|pancreas(1)|prostate(1)|skin(1)|upper_aerodigestive_tract(2)|urinary_tract(2)	54	all_cancers(143;2.51e-11)|Ovarian(172;0.0339)|Breast(254;0.247)		Epithelial(37;1.02e-33)|OV - Ovarian serous cystadenocarcinoma(80;4.81e-22)			TGCTCTTTGCCAGAGAAATTC	0.408000													15	9					0	0	1	0	0
MED13L	23389	broad.mit.edu	37	12	116429391	116429391	+	Missense_Mutation	SNP	A	A	C			TCGA-WB-A81Q-01A-11D-A35I-08	TCGA-WB-A81Q-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2be35d9d-a4ba-438f-b5b7-f6187fa78554	68f9891f-65a7-48ae-95c6-e807a953400b	g.chr12:116429391A>C	ENST00000281928.3	-	17	3574	c.3368T>G	c.(3367-3369)tTt>tGt	p.F1123C		NM_015335.4	NP_056150.1	Q71F56	MD13L_HUMAN	mediator complex subunit 13-like	1123					regulation of transcription from RNA polymerase II promoter|transcription, DNA-dependent					NS(2)|breast(1)|endometrium(9)|kidney(3)|large_intestine(18)|lung(34)|ovary(4)|prostate(4)|skin(6)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(2)	85	all_neural(191;0.117)|Medulloblastoma(191;0.163)			BRCA - Breast invasive adenocarcinoma(302;0.0407)		TCTGTCTTTAAAGATATTCAT	0.517000													41	41					0	0	1	0	0
SPTA1	6708	broad.mit.edu	37	1	158644382	158644382	+	Missense_Mutation	SNP	G	G	A			TCGA-WB-A81Q-01A-11D-A35I-08	TCGA-WB-A81Q-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2be35d9d-a4ba-438f-b5b7-f6187fa78554	68f9891f-65a7-48ae-95c6-e807a953400b	g.chr1:158644382G>A	ENST00000368148.3	-	9	1376	c.1196C>T	c.(1195-1197)cCa>cTa	p.P399L	SPTA1_ENST00000368147.3_Missense_Mutation_p.P399L	NM_003126.2	NP_003117.2	P02549	SPTA1_HUMAN	spectrin, alpha, erythrocytic 1 (elliptocytosis 2)	399					actin filament capping|actin filament organization|axon guidance|regulation of cell shape	cytosol|intrinsic to internal side of plasma membrane|spectrin|spectrin-associated cytoskeleton	actin filament binding|calcium ion binding|structural constituent of cytoskeleton			NS(3)|breast(7)|cervix(1)|endometrium(22)|kidney(9)|large_intestine(29)|liver(2)|lung(183)|ovary(5)|prostate(18)|skin(11)|soft_tissue(1)|stomach(1)|upper_aerodigestive_tract(9)|urinary_tract(6)	307	all_hematologic(112;0.0378)					CACATCTGTTGGCAGCTCATC	0.512000													11	299					0	0	1	0	0
PSMD1	5707	broad.mit.edu	37	2	231931688	231931688	+	Missense_Mutation	SNP	C	C	A			TCGA-WB-A81Q-01A-11D-A35I-08	TCGA-WB-A81Q-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2be35d9d-a4ba-438f-b5b7-f6187fa78554	68f9891f-65a7-48ae-95c6-e807a953400b	g.chr2:231931688C>A	ENST00000308696.6	+	5	535	c.373C>A	c.(373-375)Cca>Aca	p.P125T	PSMD1_ENST00000373635.4_Missense_Mutation_p.P125T|PSMD1_ENST00000409643.1_Missense_Mutation_p.P125T	NM_002807.3	NP_002798.2	Q99460	PSMD1_HUMAN	proteasome (prosome, macropain) 26S subunit, non-ATPase, 1	125					anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process|apoptosis|DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest|G1/S transition of mitotic cell cycle|M/G1 transition of mitotic cell cycle|mRNA metabolic process|negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle|positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle|regulation of apoptosis|regulation of cellular amino acid metabolic process|regulation of protein catabolic process|S phase of mitotic cell cycle|viral reproduction	proteasome regulatory particle	enzyme regulator activity|protein binding			breast(1)|endometrium(2)|kidney(2)|large_intestine(10)|lung(10)|ovary(1)|prostate(1)|skin(4)	31		Ovarian(221;0.000626)|Medulloblastoma(418;0.0109)|Renal(207;0.0112)|Lung NSC(271;0.0538)|all_lung(227;0.0713)|all_hematologic(139;0.0748)|Acute lymphoblastic leukemia(138;0.167)		Epithelial(121;4e-26)|LUSC - Lung squamous cell carcinoma(224;0.0138)|Lung(119;0.0168)	Bortezomib(DB00188)	AGAAAAAAAACCAATTGACCA	0.378000													18	37					1.01871e-10	1.12058e-10	1	1	0
PCSK5	5125	broad.mit.edu	37	9	78790136	78790136	+	Missense_Mutation	SNP	T	T	C	rs62556589		TCGA-WB-A81Q-01A-11D-A35I-08	TCGA-WB-A81Q-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2be35d9d-a4ba-438f-b5b7-f6187fa78554	68f9891f-65a7-48ae-95c6-e807a953400b	g.chr9:78790136T>C	ENST00000376767.3	+	14	2503	c.1991T>C	c.(1990-1992)aTg>aCg	p.M664T	PCSK5_ENST00000545128.1_Intron|PCSK5_ENST00000376752.4_Intron			Q92824	PCSK5_HUMAN	proprotein convertase subtilisin/kexin type 5	0	CRM (Cys-rich motif).				anterior/posterior pattern formation|cell-cell signaling|cytokine biosynthetic process|embryo implantation|embryonic digestive tract development|embryonic skeletal system development|heart development|kidney development|limb morphogenesis|nerve growth factor processing|nerve growth factor receptor signaling pathway|peptide biosynthetic process|renin secretion into blood stream|respiratory tube development|signal peptide processing|viral assembly, maturation, egress, and release	extracellular space|Golgi lumen|stored secretory granule	peptide binding|serine-type endopeptidase activity			NS(1)|breast(1)|endometrium(6)|haematopoietic_and_lymphoid_tissue(3)|kidney(2)|large_intestine(7)|liver(2)|lung(25)|ovary(2)|pancreas(1)|prostate(2)|skin(3)	55						tggaatggaatgaaatggaat	0.423000													3	27					0	0	1	0	0
WASH3P	374666	broad.mit.edu	37	15	102515299	102515299	+	RNA	SNP	G	G	A			TCGA-WB-A81Q-01A-11D-A35I-08	TCGA-WB-A81Q-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2be35d9d-a4ba-438f-b5b7-f6187fa78554	68f9891f-65a7-48ae-95c6-e807a953400b	g.chr15:102515299G>A	ENST00000557932.1	+	0	1145																		p.G374S(10)		central_nervous_system(1)|endometrium(6)|kidney(11)|prostate(5)|stomach(1)|urinary_tract(1)	25						TGGGGGCATCGGCAAGGCCAA	0.652000													4	48					0	0	1	0	0
TRPC6	7225	broad.mit.edu	37	11	101375232	101375232	+	Missense_Mutation	SNP	T	T	G			TCGA-WB-A81Q-01A-11D-A35I-08	TCGA-WB-A81Q-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2be35d9d-a4ba-438f-b5b7-f6187fa78554	68f9891f-65a7-48ae-95c6-e807a953400b	g.chr11:101375232T>G	ENST00000344327.3	-	2	892	c.468A>C	c.(466-468)gaA>gaC	p.E156D	TRPC6_ENST00000348423.4_Missense_Mutation_p.E156D|TRPC6_ENST00000360497.4_Missense_Mutation_p.E156D|TRPC6_ENST00000532133.1_Missense_Mutation_p.E156D	NM_004621.5	NP_004612.2	Q9Y210	TRPC6_HUMAN	transient receptor potential cation channel, subfamily C, member 6	156					axon guidance|platelet activation|positive regulation of calcium ion transport via store-operated calcium channel activity	integral to membrane|plasma membrane	protein binding			autonomic_ganglia(1)|breast(3)|central_nervous_system(2)|endometrium(3)|kidney(3)|large_intestine(14)|lung(17)|ovary(2)|pancreas(1)|prostate(1)|skin(6)|upper_aerodigestive_tract(1)|urinary_tract(1)	55		Acute lymphoblastic leukemia(157;0.000918)|all_hematologic(158;0.0162)		BRCA - Breast invasive adenocarcinoma(274;0.0442)		GAGAGAGGTTTTCTTTCTTGA	0.448000													13	44					0	0	1	0	0
TAB2	23118	broad.mit.edu	37	6	149718827	149718827	+	Missense_Mutation	SNP	A	A	C			TCGA-WB-A81Q-01A-11D-A35I-08	TCGA-WB-A81Q-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2be35d9d-a4ba-438f-b5b7-f6187fa78554	68f9891f-65a7-48ae-95c6-e807a953400b	g.chr6:149718827A>C	ENST00000367456.1	+	5	2268	c.1691A>C	c.(1690-1692)gAg>gCg	p.E564A	TAB2_ENST00000286332.5_Missense_Mutation_p.E564A|TAB2_ENST00000538427.1_Missense_Mutation_p.E564A|TAB2_ENST00000536230.1_Missense_Mutation_p.E532A			Q9NYJ8	TAB2_HUMAN	TGF-beta activated kinase 1/MAP3K7 binding protein 2	564					activation of MAPK activity|heart development|I-kappaB kinase/NF-kappaB cascade|innate immune response|JNK cascade|MyD88-dependent toll-like receptor signaling pathway|MyD88-independent toll-like receptor signaling pathway|positive regulation of I-kappaB kinase/NF-kappaB cascade|positive regulation of NF-kappaB transcription factor activity|stress-activated MAPK cascade|T cell receptor signaling pathway|Toll signaling pathway|toll-like receptor 1 signaling pathway|toll-like receptor 2 signaling pathway|toll-like receptor 3 signaling pathway|toll-like receptor 4 signaling pathway	cytosol|endosome membrane|plasma membrane	K63-linked polyubiquitin binding|zinc ion binding			breast(2)|endometrium(6)|kidney(3)|large_intestine(2)|lung(7)|ovary(1)|urinary_tract(1)	22						TTAAAATCTGAGGTTAATGAA	0.368000													5	130					0	0	1	0	0
FRG1BP	284802	broad.mit.edu	37	20	29628283	29628283	+	Silent	SNP	G	G	C			TCGA-WB-A81Q-01A-11D-A35I-08	TCGA-WB-A81Q-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2be35d9d-a4ba-438f-b5b7-f6187fa78554	68f9891f-65a7-48ae-95c6-e807a953400b	g.chr20:29628283G>C	ENST00000278882.3	+	6	665	c.285G>C	c.(283-285)ggG>ggC	p.G95G	FRG1B_ENST00000439954.2_Silent_p.G100G|FRG1B_ENST00000358464.4_Silent_p.G95G														p.G95G(4)		endometrium(10)|kidney(21)|lung(3)|pancreas(1)|prostate(9)|urinary_tract(9)	53						ATGAAGCAGGGGACATAGAAG	0.378000													5	105					0	0	1	0	0
CEACAM6	4680	broad.mit.edu	37	19	42265395	42265395	+	Silent	SNP	G	G	A			TCGA-WB-A81Q-01A-11D-A35I-08	TCGA-WB-A81Q-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2be35d9d-a4ba-438f-b5b7-f6187fa78554	68f9891f-65a7-48ae-95c6-e807a953400b	g.chr19:42265395G>A	ENST00000199764.6	+	3	881	c.663G>A	c.(661-663)gcG>gcA	p.A221A	AC011513.4_ENST00000601409.1_RNA	NM_002483.4	NP_002474.3	P40199	CEAM6_HUMAN	carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)	221	Ig-like C2-type 1.				cell-cell signaling|signal transduction	anchored to membrane|integral to plasma membrane				breast(1)|kidney(4)|large_intestine(1)|lung(4)|ovary(2)|prostate(2)|skin(2)|stomach(1)|urinary_tract(1)	18				OV - Ovarian serous cystadenocarcinoma(3;0.00575)|all cancers(3;0.0352)|Epithelial(262;0.0797)		AGAACCCAGCGAGTGCCAACC	0.542000													95	126					0	0	1	0	0
FRG1BP	284802	broad.mit.edu	37	20	29625875	29625875	+	Missense_Mutation	SNP	T	T	C	rs143761036	by1000genomes	TCGA-WB-A81Q-01A-11D-A35I-08	TCGA-WB-A81Q-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2be35d9d-a4ba-438f-b5b7-f6187fa78554	68f9891f-65a7-48ae-95c6-e807a953400b	g.chr20:29625875T>C	ENST00000278882.3	+	5	499	c.119T>C	c.(118-120)aTc>aCc	p.I40T	FRG1B_ENST00000439954.2_Missense_Mutation_p.I45T|FRG1B_ENST00000358464.4_Missense_Mutation_p.I40T														p.I40T(4)		endometrium(10)|kidney(21)|lung(3)|pancreas(1)|prostate(9)|urinary_tract(9)	53						ATGTACAGAATCGCCCTGAAA	0.358000													7	82					0	0	1	0	0
KCNC1	3746	broad.mit.edu	37	11	17757753	17757753	+	Silent	SNP	G	G	C			TCGA-WB-A81Q-01A-11D-A35I-08	TCGA-WB-A81Q-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2be35d9d-a4ba-438f-b5b7-f6187fa78554	68f9891f-65a7-48ae-95c6-e807a953400b	g.chr11:17757753G>C	ENST00000379472.3	+	1	234	c.204G>C	c.(202-204)ctG>ctC	p.L68L	KCNC1_ENST00000265969.6_Silent_p.L68L	NM_004976.4	NP_004967.1	P48547	KCNC1_HUMAN	potassium voltage-gated channel, Shaw-related subfamily, member 1	68						voltage-gated potassium channel complex	voltage-gated potassium channel activity			breast(1)|cervix(1)|endometrium(6)|kidney(3)|large_intestine(9)|lung(7)|pancreas(1)|prostate(3)|skin(1)|upper_aerodigestive_tract(1)	33						CGCACATCCTGAACTACTACC	0.672000													25	24					0	0	1	0	0
MLLT1	4298	broad.mit.edu	37	19	6270667	6270667	+	Missense_Mutation	SNP	G	G	C			TCGA-WB-A81Q-01A-11D-A35I-08	TCGA-WB-A81Q-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2be35d9d-a4ba-438f-b5b7-f6187fa78554	68f9891f-65a7-48ae-95c6-e807a953400b	g.chr19:6270667G>C	ENST00000252674.7	-	2	279	c.116C>G	c.(115-117)cCc>cGc	p.P39R		NM_005934.3	NP_005925.2	Q03111	ENL_HUMAN	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1	39	YEATS.				regulation of transcription, DNA-dependent|transcription from RNA polymerase II promoter	cytoplasm|nucleolus	DNA binding|protein binding			endometrium(3)|kidney(3)|large_intestine(2)|lung(5)|prostate(2)|skin(2)	17						ACATTGCTCGGGGCCGCGGAC	0.622000			T	MLL	AL						OREG0025198	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	31	30					0	0	1	0	0
ANKRD20A8P	729171	broad.mit.edu	37	2	95522786	95522786	+	RNA	SNP	T	T	C			TCGA-WB-A81Q-01A-11D-A35I-08	TCGA-WB-A81Q-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2be35d9d-a4ba-438f-b5b7-f6187fa78554	68f9891f-65a7-48ae-95c6-e807a953400b	g.chr2:95522786T>C	ENST00000432432.2	-	0	241					NR_040113.1													p.K44K(1)									CGGCGTCGCCTTTGACAGCTG	0.687000													3	43					0	0	1	0	0
MLPH	79083	broad.mit.edu	37	2	238419387	238419387	+	Missense_Mutation	SNP	G	G	A			TCGA-WB-A81Q-01A-11D-A35I-08	TCGA-WB-A81Q-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2be35d9d-a4ba-438f-b5b7-f6187fa78554	68f9891f-65a7-48ae-95c6-e807a953400b	g.chr2:238419387G>A	ENST00000264605.3	+	3	575	c.281G>A	c.(280-282)cGc>cAc	p.R94H	MLPH_ENST00000445024.2_Missense_Mutation_p.R94H|MLPH_ENST00000410032.1_Missense_Mutation_p.R94H|MLPH_ENST00000338530.4_Missense_Mutation_p.R94H|MLPH_ENST00000468178.1_3'UTR|MLPH_ENST00000409373.1_Missense_Mutation_p.R94H	NM_024101.5	NP_077006.1	Q9BV36	MELPH_HUMAN	melanophilin	94	RabBD.						metal ion binding			NS(1)|breast(3)|cervix(1)|endometrium(3)|large_intestine(2)|lung(11)|ovary(1)|stomach(2)|upper_aerodigestive_tract(1)	25		Breast(86;0.000381)|Renal(207;0.000966)|Ovarian(221;0.0695)|all_hematologic(139;0.095)|all_lung(227;0.17)|Melanoma(123;0.203)		Epithelial(121;1.17e-21)|OV - Ovarian serous cystadenocarcinoma(60;1.02e-10)|Kidney(56;4.23e-09)|KIRC - Kidney renal clear cell carcinoma(57;1.15e-07)|BRCA - Breast invasive adenocarcinoma(100;0.000439)|Lung(119;0.0132)|LUSC - Lung squamous cell carcinoma(224;0.0316)		AGCTGTGGCCGCGTCCACCCG	0.597000													3	46					0	0	1	0	0
NEB	4703	broad.mit.edu	37	2	152466570	152466570	+	Missense_Mutation	SNP	T	T	C			TCGA-WB-A81Q-01A-11D-A35I-08	TCGA-WB-A81Q-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2be35d9d-a4ba-438f-b5b7-f6187fa78554	68f9891f-65a7-48ae-95c6-e807a953400b	g.chr2:152466570T>C	ENST00000427231.2	-	81	12285	c.12083A>G	c.(12082-12084)gAt>gGt	p.D4028G	NEB_ENST00000409198.1_Missense_Mutation_p.D3785G|NEB_ENST00000397345.3_Missense_Mutation_p.D4028G|NEB_ENST00000603639.1_Missense_Mutation_p.D4028G|NEB_ENST00000172853.10_Missense_Mutation_p.D3785G|NEB_ENST00000604864.1_Missense_Mutation_p.D4028G	NM_001164507.1	NP_001157979.1	P20929	NEBU_HUMAN	nebulin	4027					muscle filament sliding|muscle organ development|regulation of actin filament length|somatic muscle development	actin cytoskeleton|cytosol|Z disc	actin binding|structural constituent of muscle			NS(5)|autonomic_ganglia(3)|breast(9)|central_nervous_system(5)|cervix(3)|endometrium(35)|kidney(16)|large_intestine(77)|liver(1)|lung(99)|ovary(9)|pancreas(3)|prostate(13)|skin(7)|stomach(8)|upper_aerodigestive_tract(6)|urinary_tract(2)	301				BRCA - Breast invasive adenocarcinoma(221;0.219)		CTTGGGATCATCTTCAATGCT	0.418000													19	31					0	0	1	0	0
JOSD2	126119	broad.mit.edu	37	19	51013652	51013652	+	Missense_Mutation	SNP	T	T	C			TCGA-WB-A81Q-01A-11D-A35I-08	TCGA-WB-A81Q-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2be35d9d-a4ba-438f-b5b7-f6187fa78554	68f9891f-65a7-48ae-95c6-e807a953400b	g.chr19:51013652T>C	ENST00000598418.1	-	2	290	c.37A>G	c.(37-39)Acc>Gcc	p.T13A	JOSD2_ENST00000391815.3_Missense_Mutation_p.T13A|JOSD2_ENST00000601423.1_Missense_Mutation_p.T13A|JOSD2_ENST00000595669.1_Missense_Mutation_p.T13A	NM_001270639.1|NM_001270640.1	NP_001257568.1|NP_001257569.1	Q8TAC2	JOS2_HUMAN	Josephin domain containing 2	13	Josephin.				protein deubiquitination		ubiquitin-specific protease activity			kidney(1)|lung(3)|prostate(1)	5		all_neural(266;0.131)		OV - Ovarian serous cystadenocarcinoma(262;0.00743)|GBM - Glioblastoma multiforme(134;0.0364)		TGGTACACGGTGGGTGGGCTC	0.662000													42	43					0	0	1	0	0
ANKHD1	54882	broad.mit.edu	37	5	139889715	139889715	+	Silent	SNP	G	G	A			TCGA-WB-A81Q-01A-11D-A35I-08	TCGA-WB-A81Q-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2be35d9d-a4ba-438f-b5b7-f6187fa78554	68f9891f-65a7-48ae-95c6-e807a953400b	g.chr5:139889715G>A	ENST00000297183.6	+	22	4177	c.4053G>A	c.(4051-4053)gtG>gtA	p.V1351V	ANKHD1_ENST00000360839.2_Silent_p.V1351V|ANKHD1-EIF4EBP3_ENST00000532219.1_Silent_p.V1351V	NM_020690.5	NP_065741.3			ankyrin repeat and KH domain containing 1											breast(2)|endometrium(8)|kidney(6)|large_intestine(14)|lung(18)|ovary(5)|prostate(2)|skin(3)|urinary_tract(2)	60			KIRC - Kidney renal clear cell carcinoma(527;0.00112)|Kidney(363;0.00191)			GTGCTGATGTGGATGCAGCAG	0.423000													8	56					0	0	1	0	0
EIF5B	9669	broad.mit.edu	37	2	99978277	99978277	+	Missense_Mutation	SNP	G	G	T			TCGA-WB-A81Q-01A-11D-A35I-08	TCGA-WB-A81Q-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2be35d9d-a4ba-438f-b5b7-f6187fa78554	68f9891f-65a7-48ae-95c6-e807a953400b	g.chr2:99978277G>T	ENST00000289371.5	+	4	1115	c.913G>T	c.(913-915)Gca>Tca	p.A305S		NM_015904.3	NP_056988.3	O60841	IF2P_HUMAN	eukaryotic translation initiation factor 5B	305					regulation of translational initiation	cytosol	GTP binding|GTPase activity|protein binding|translation initiation factor activity			breast(1)|endometrium(3)|kidney(1)|large_intestine(5)|lung(13)|ovary(2)|pancreas(1)|prostate(1)|skin(2)|upper_aerodigestive_tract(1)|urinary_tract(1)	31						TCCCACAGCTGCAGAAGGTTG	0.388000													4	170					0.150653	0.154157	1	1	0
MGAT4A	11320	broad.mit.edu	37	2	99256446	99256446	+	Missense_Mutation	SNP	G	G	A			TCGA-WB-A81Q-01A-11D-A35I-08	TCGA-WB-A81Q-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2be35d9d-a4ba-438f-b5b7-f6187fa78554	68f9891f-65a7-48ae-95c6-e807a953400b	g.chr2:99256446G>A	ENST00000393487.1	-	12	1460	c.1147C>T	c.(1147-1149)Cca>Tca	p.P383S	MGAT4A_ENST00000414521.2_Missense_Mutation_p.P255S|MGAT4A_ENST00000264968.2_Missense_Mutation_p.P383S|MGAT4A_ENST00000409391.1_Missense_Mutation_p.P383S	NM_012214.2	NP_036346.1	Q9UM21	MGT4A_HUMAN	mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A	383					N-glycan processing|post-translational protein modification|protein N-linked glycosylation via asparagine	extracellular region|Golgi membrane|integral to membrane	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity|metal ion binding			NS(1)|breast(2)|endometrium(2)|kidney(2)|large_intestine(3)|lung(7)|skin(1)|stomach(1)	19						AGAAGTAATGGTTTCATATAA	0.343000													6	65					0	0	1	0	0
SLC22A5	6584	broad.mit.edu	37	5	131719958	131719958	+	Missense_Mutation	SNP	G	G	C			TCGA-WB-A81Q-01A-11D-A35I-08	TCGA-WB-A81Q-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2be35d9d-a4ba-438f-b5b7-f6187fa78554	68f9891f-65a7-48ae-95c6-e807a953400b	g.chr5:131719958G>C	ENST00000245407.3	+	3	838	c.617G>C	c.(616-618)gGc>gCc	p.G206A	SLC22A5_ENST00000435065.2_Missense_Mutation_p.G230A	NM_003060.3	NP_003051.1	O76082	S22A5_HUMAN	solute carrier family 22 (organic cation/carnitine transporter), member 5	206					positive regulation of intestinal epithelial structure maintenance|quorum sensing involved in interaction with host|sodium ion transport|sodium-dependent organic cation transport	apical plasma membrane|brush border membrane|integral to membrane	ATP binding|carnitine transporter activity|PDZ domain binding|symporter activity			NS(1)|endometrium(1)|kidney(1)|large_intestine(2)|lung(2)|stomach(1)	8		all_cancers(142;0.0751)|Breast(839;0.198)	KIRC - Kidney renal clear cell carcinoma(527;0.0186)|Kidney(363;0.0365)		L-Carnitine(DB00583)	GTAGGCATGGGCCAGATCTCC	0.483000													31	49					0	0	1	0	0
ARHGEF19	128272	broad.mit.edu	37	1	16532568	16532568	+	Frame_Shift_Del	DEL	C	C	-			TCGA-WB-A81Q-01A-11D-A35I-08	TCGA-WB-A81Q-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2be35d9d-a4ba-438f-b5b7-f6187fa78554	68f9891f-65a7-48ae-95c6-e807a953400b	g.chr1:16532568delC	ENST00000270747.3	-	8	1445	c.1309delG	c.(1309-1311)acfs	p.D437fs	ARHGEF19_ENST00000421561.1_Frame_Shift_Del_p.D437fs|ARHGEF19_ENST00000478117.1_5'UTR	NM_153213.3	NP_694945.2	Q8IW93	ARHGJ_HUMAN	Rho guanine nucleotide exchange factor (GEF) 19	437	DH.				regulation of actin cytoskeleton organization	intracellular	GTPase activator activity|Rho guanyl-nucleotide exchange factor activity			cervix(1)|endometrium(1)|lung(3)|ovary(2)|prostate(1)|skin(3)|upper_aerodigestive_tract(1)	12		Colorectal(325;0.000147)|Renal(390;0.00145)|Breast(348;0.00224)|Lung NSC(340;0.00566)|all_lung(284;0.00831)|Myeloproliferative disorder(586;0.0393)|Ovarian(437;0.0646)		UCEC - Uterine corpus endometrioid carcinoma (279;0.018)|Colorectal(212;3.48e-07)|COAD - Colon adenocarcinoma(227;2.19e-05)|BRCA - Breast invasive adenocarcinoma(304;9.46e-05)|Kidney(64;0.000171)|KIRC - Kidney renal clear cell carcinoma(64;0.00258)|STAD - Stomach adenocarcinoma(313;0.0117)|READ - Rectum adenocarcinoma(331;0.0649)		TGCTCCAGGTCCTGCAGGAAC	0.657													2	4	---	---	---	---					
MAN1C1	57134	broad.mit.edu	37	1	25944705	25944705	+	Frame_Shift_Del	DEL	C	C	-			TCGA-WB-A81Q-01A-11D-A35I-08	TCGA-WB-A81Q-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2be35d9d-a4ba-438f-b5b7-f6187fa78554	68f9891f-65a7-48ae-95c6-e807a953400b	g.chr1:25944705delC	ENST00000374332.4	+	1	747	c.417delC	c.(415-417)gtfs	p.V139fs	MAN1C1_ENST00000263979.3_5'UTR	NM_020379.2	NP_065112.1	Q9NR34	MA1C1_HUMAN	mannosidase, alpha, class 1C, member 1	139					post-translational protein modification|protein N-linked glycosylation via asparagine	integral to Golgi membrane	calcium ion binding|mannosyl-oligosaccharide 1,2-alpha-mannosidase activity			NS(1)|endometrium(4)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(8)|lung(7)|pancreas(1)|prostate(1)|skin(2)	25		Colorectal(325;3.78e-05)|Lung NSC(340;0.000181)|all_lung(284;0.000245)|Renal(390;0.000714)|Ovarian(437;0.00159)|Breast(348;0.0156)|Myeloproliferative disorder(586;0.0257)|all_neural(195;0.0515)|Esophageal squamous(538;0.232)		UCEC - Uterine corpus endometrioid carcinoma (279;0.0574)|OV - Ovarian serous cystadenocarcinoma(117;2.46e-25)|Colorectal(126;1.15e-07)|COAD - Colon adenocarcinoma(152;4.31e-06)|STAD - Stomach adenocarcinoma(196;0.00125)|BRCA - Breast invasive adenocarcinoma(304;0.00141)|KIRC - Kidney renal clear cell carcinoma(1967;0.00146)|GBM - Glioblastoma multiforme(114;0.0149)|READ - Rectum adenocarcinoma(331;0.0803)		ACGAGGGCGTCCCTTTCCGCT	0.716													2	4	---	---	---	---					
TCHH	7062	broad.mit.edu	37	1	152082957	152082959	+	In_Frame_Del	DEL	CTC	CTC	-	rs143222885	by1000genomes	TCGA-WB-A81Q-01A-11D-A35I-08	TCGA-WB-A81Q-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2be35d9d-a4ba-438f-b5b7-f6187fa78554	68f9891f-65a7-48ae-95c6-e807a953400b	g.chr1:152082957_152082959delCTC	ENST00000368804.1	-	2	2733_2735	c.2734_2736delGAG	c.(2734-2736)del	p.E912del		NM_007113.2	NP_009044.2	Q07283	TRHY_HUMAN	trichohyalin	912	10 X 30 AA tandem repeats.				keratinization	cytoskeleton	calcium ion binding			NS(2)|breast(4)|central_nervous_system(1)|cervix(1)|endometrium(20)|kidney(9)|large_intestine(16)|lung(33)|ovary(3)|pancreas(1)|prostate(4)|skin(5)|upper_aerodigestive_tract(2)|urinary_tract(4)	105	Hepatocellular(266;0.0877)|Melanoma(130;0.116)|all_hematologic(923;0.127)		LUSC - Lung squamous cell carcinoma(543;0.206)			CTCTCTGTAGCTCCTCCTCCTCC	0.586													7	306	---	---	---	---					
FRG1BP	284802	broad.mit.edu	37	20	29625899	29625900	+	Frame_Shift_Ins	INS	-	-	AT			TCGA-WB-A81Q-01A-11D-A35I-08	TCGA-WB-A81Q-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2be35d9d-a4ba-438f-b5b7-f6187fa78554	68f9891f-65a7-48ae-95c6-e807a953400b	g.chr20:29625899_29625900insAT	ENST00000278882.3	+	5	523_524	c.143_144insAT	c.(142-144)atafs	p.I48fs	FRG1B_ENST00000358464.4_Frame_Shift_Ins_p.I48fs|FRG1B_ENST00000439954.2_Frame_Shift_Ins_p.I53fs																endometrium(10)|kidney(21)|lung(3)|pancreas(1)|prostate(9)|urinary_tract(9)	53						GGCTATGGAAAATATCTTGGTA	0.342													7	121	---	---	---	---					
SCARNA15	677778	broad.mit.edu	37	20	41933319	41933319	+	RNA	DEL	A	A	-	rs79619980		TCGA-WB-A81Q-01A-11D-A35I-08	TCGA-WB-A81Q-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2be35d9d-a4ba-438f-b5b7-f6187fa78554	68f9891f-65a7-48ae-95c6-e807a953400b	g.chr20:41933319delA	ENST00000516384.1	+	0	125																											TATCaatagcaaaaaaaaaaa	0.318													2	4	---	---	---	---					
KANTR	102723508	broad.mit.edu	37	X	53142506	53142507	+	RNA	INS	-	-	A	rs146094031		TCGA-WB-A81Q-01A-11D-A35I-08	TCGA-WB-A81Q-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2be35d9d-a4ba-438f-b5b7-f6187fa78554	68f9891f-65a7-48ae-95c6-e807a953400b	g.chrX:53142506_53142507insA	ENST00000604849.1	+	0	96																											AAAACACACACACAAAAAAAAA	0.356													4	6	---	---	---	---