Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
DSCR9	0	broad.mit.edu	37	21	38593635	38593635	+	RNA	SNP	G	G	C			TCGA-2A-AAYF-01A-11D-A41K-08	TCGA-2A-AAYF-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5d4f8ba6-7ff3-40ec-af29-7b3450f813a2	b4ade944-957e-4ec1-a880-e330b8de3980	g.chr21:38593635G>C	ENST00000454482.2	+	0	1242					NR_026719.2																						CTAGGCAGGCGCGCCCCGCCC	0.642000													16	26					0	0	1	0	0
MCMDC2	157777	broad.mit.edu	37	8	67786786	67786786	+	Missense_Mutation	SNP	C	C	G			TCGA-2A-AAYF-01A-11D-A41K-08	TCGA-2A-AAYF-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5d4f8ba6-7ff3-40ec-af29-7b3450f813a2	b4ade944-957e-4ec1-a880-e330b8de3980	g.chr8:67786786C>G	ENST00000422365.2	+	4	421	c.250C>G	c.(250-252)Ctc>Gtc	p.L84V	MCMDC2_ENST00000541540.1_Missense_Mutation_p.L21V|MCMDC2_ENST00000492775.1_Missense_Mutation_p.L84V|MCMDC2_ENST00000396592.3_Missense_Mutation_p.L84V|MCMDC2_ENST00000313616.5_Missense_Mutation_p.L84V|MCMDC2_ENST00000469823.1_3'UTR	NM_173518.4	NP_775789.3	Q4G0Z9	CH045_HUMAN	minichromosome maintenance domain containing 2	84					DNA replication		ATP binding|DNA binding			endometrium(2)|kidney(2)|lung(5)	9						TGTTAAGACTCTCTCATTAAT	0.294000													4	36					0	0	1	0	0
HSP90AA1	3320	broad.mit.edu	37	14	102551071	102551071	+	Missense_Mutation	SNP	C	C	G			TCGA-2A-AAYF-01A-11D-A41K-08	TCGA-2A-AAYF-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5d4f8ba6-7ff3-40ec-af29-7b3450f813a2	b4ade944-957e-4ec1-a880-e330b8de3980	g.chr14:102551071C>G	ENST00000334701.7	-	6	1575	c.1294G>C	c.(1294-1296)Gga>Cga	p.G432R	HSP90AA1_ENST00000216281.8_Missense_Mutation_p.G310R|HSP90AA1_ENST00000441629.2_Missense_Mutation_p.G131R	NM_001017963.2	NP_001017963.2	P07900	HS90A_HUMAN	heat shock protein 90kDa alpha (cytosolic), class A member 1	310					axon guidance|cellular chaperone-mediated protein complex assembly|G2/M transition of mitotic cell cycle|nitric oxide metabolic process|positive regulation of nitric oxide biosynthetic process|protein import into mitochondrial outer membrane|protein refolding|regulation of nitric-oxide synthase activity|response to unfolded protein|signal transduction	cytosol|melanosome|plasma membrane	ATP binding|ATPase activity|nitric-oxide synthase regulator activity|protein homodimerization activity|TPR domain binding|unfolded protein binding			breast(1)|central_nervous_system(2)|endometrium(2)|kidney(6)|large_intestine(3)|liver(1)|lung(10)|ovary(2)|prostate(1)	28					Rifabutin(DB00615)	TAGAATTCTCCGTACTCCTCA	0.418000													57	89					0	0	1	0	0
NPIPA5	100288332	broad.mit.edu	37	16	15457701	15457701	+	Missense_Mutation	SNP	G	G	A			TCGA-2A-AAYF-01A-11D-A41K-08	TCGA-2A-AAYF-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5d4f8ba6-7ff3-40ec-af29-7b3450f813a2	b4ade944-957e-4ec1-a880-e330b8de3980	g.chr16:15457701G>A	ENST00000360151.4	-	8	867	c.868C>T	c.(868-870)Ctc>Ttc	p.L290F		NM_001277325.1	NP_001264254.1			nuclear pore complex interacting protein family, member A5									p.L290F(2)									AGGGGAGTGAGCAGACACTCG	0.562000													4	152					0	0	1	0	0
GRM8	0	broad.mit.edu	37	7	126882812	126882812	+	Silent	SNP	G	G	A			TCGA-2A-AAYF-01A-11D-A41K-08	TCGA-2A-AAYF-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5d4f8ba6-7ff3-40ec-af29-7b3450f813a2	b4ade944-957e-4ec1-a880-e330b8de3980	g.chr7:126882812G>A	ENST00000339582.2	-	2	1255	c.447C>T	c.(445-447)ggC>ggT	p.G149G	GRM8_ENST00000405249.1_Silent_p.G149G|GRM8_ENST00000358373.3_Silent_p.G149G|GRM8_ENST00000444921.2_Silent_p.G149G			O00222	GRM8_HUMAN	glutamate receptor, metabotropic 8	149					negative regulation of cAMP biosynthetic process|sensory perception of smell|visual perception	integral to plasma membrane				breast(3)|cervix(1)|endometrium(7)|haematopoietic_and_lymphoid_tissue(4)|large_intestine(16)|lung(62)|ovary(5)|pancreas(1)|prostate(1)|skin(14)|stomach(1)|upper_aerodigestive_tract(6)|urinary_tract(4)	125		Prostate(267;0.186)			L-Glutamic Acid(DB00142)	CACCTATGACGCCAGAAATCT	0.438000										HNSCC(24;0.065)			32	56					0	0	1	0	0
HIST1H4B	8366	broad.mit.edu	37	6	26027174	26027174	+	Missense_Mutation	SNP	C	C	A			TCGA-2A-AAYF-01A-11D-A41K-08	TCGA-2A-AAYF-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5d4f8ba6-7ff3-40ec-af29-7b3450f813a2	b4ade944-957e-4ec1-a880-e330b8de3980	g.chr6:26027174C>A	ENST00000377364.3	-	1	306	c.307G>T	c.(307-309)Ggt>Tgt	p.G103C		NM_003544.2	NP_003535.1	P62805	H4_HUMAN	histone cluster 1, H4b	103					CenH3-containing nucleosome assembly at centromere|negative regulation of megakaryocyte differentiation|phosphatidylinositol-mediated signaling|telomere maintenance	nucleoplasm|nucleosome	DNA binding|protein binding			large_intestine(4)|lung(6)|ovary(2)|upper_aerodigestive_tract(1)	13						AAAGATTAACCGCCGAAGCCG	0.537000											OREG0017238	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	21	35					4.96729e-08	5.37004e-08	1	1	0
HERC2	8924	broad.mit.edu	37	15	28463681	28463681	+	Silent	SNP	G	G	A			TCGA-2A-AAYF-01A-11D-A41K-08	TCGA-2A-AAYF-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5d4f8ba6-7ff3-40ec-af29-7b3450f813a2	b4ade944-957e-4ec1-a880-e330b8de3980	g.chr15:28463681G>A	ENST00000261609.7	-	38	6090	c.5982C>T	c.(5980-5982)tgC>tgT	p.C1994C		NM_004667.5	NP_004658.3	O95714	HERC2_HUMAN	HECT and RLD domain containing E3 ubiquitin protein ligase 2	1994					DNA repair|intracellular protein transport|protein ubiquitination involved in ubiquitin-dependent protein catabolic process	nucleus	guanyl-nucleotide exchange factor activity|heme binding|protein binding|ubiquitin-protein ligase activity|zinc ion binding	p.C1994C(1)		NS(1)|autonomic_ganglia(1)|breast(3)|central_nervous_system(3)|cervix(3)|endometrium(20)|kidney(11)|large_intestine(33)|lung(95)|ovary(7)|prostate(8)|skin(7)|upper_aerodigestive_tract(8)|urinary_tract(4)	204		all_lung(180;1.3e-11)|Breast(32;0.000194)|Colorectal(260;0.227)		all cancers(64;3.93e-09)|Epithelial(43;9.99e-08)|BRCA - Breast invasive adenocarcinoma(123;0.0271)|GBM - Glioblastoma multiforme(186;0.0497)|Lung(196;0.199)		GCAGCAGTCCGCATAAAGTCT	0.517000													4	145					0	0	1	0	0
SBSN	374897	broad.mit.edu	37	19	36018434	36018434	+	Silent	SNP	C	C	T			TCGA-2A-AAYF-01A-11D-A41K-08	TCGA-2A-AAYF-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5d4f8ba6-7ff3-40ec-af29-7b3450f813a2	b4ade944-957e-4ec1-a880-e330b8de3980	g.chr19:36018434C>T	ENST00000452271.2	-	1	778	c.750G>A	c.(748-750)gcG>gcA	p.A250A	SBSN_ENST00000518157.1_Intron	NM_001166034.1	NP_001159506.1	Q6UWP8	SBSN_HUMAN	suprabasin	123						extracellular region				large_intestine(5)|lung(6)|ovary(1)|prostate(2)	14	all_lung(56;1.62e-08)|Lung NSC(56;2.47e-08)|Esophageal squamous(110;0.162)		LUSC - Lung squamous cell carcinoma(66;0.0724)			CGGCCTGCCCCGCAGCATGGT	0.627000													3	5					0	0	1	0	0
IGHG2	0	broad.mit.edu	37	14	106110891	106110891	+	RNA	SNP	C	C	G			TCGA-2A-AAYF-01A-11D-A41K-08	TCGA-2A-AAYF-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5d4f8ba6-7ff3-40ec-af29-7b3450f813a2	b4ade944-957e-4ec1-a880-e330b8de3980	g.chr14:106110891C>G	ENST00000390545.2	-	0	236																											AGGTGTAGGTCTGGGTGCCGA	0.612000													4	106					0	0	1	0	0
TMEM174	134288	broad.mit.edu	37	5	72469163	72469163	+	Silent	SNP	C	C	T	rs140016650		TCGA-2A-AAYF-01A-11D-A41K-08	TCGA-2A-AAYF-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5d4f8ba6-7ff3-40ec-af29-7b3450f813a2	b4ade944-957e-4ec1-a880-e330b8de3980	g.chr5:72469163C>T	ENST00000296776.5	+	1	142	c.93C>T	c.(91-93)tcC>tcT	p.S31S	TMEM174_ENST00000511737.1_3'UTR	NM_153217.2	NP_694949.1	Q8WUU8	TM174_HUMAN	transmembrane protein 174	31						integral to membrane				endometrium(1)|large_intestine(2)|lung(2)|ovary(1)|skin(1)	7		Lung NSC(167;0.0378)|Ovarian(174;0.0908)|Prostate(461;0.165)		OV - Ovarian serous cystadenocarcinoma(47;1.46e-54)		TCCAGGTGTCCGATGATGACA	0.567000													63	93					0	0	1	0	0
SCN3A	6328	broad.mit.edu	37	2	165952053	165952053	+	Missense_Mutation	SNP	T	T	C			TCGA-2A-AAYF-01A-11D-A41K-08	TCGA-2A-AAYF-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5d4f8ba6-7ff3-40ec-af29-7b3450f813a2	b4ade944-957e-4ec1-a880-e330b8de3980	g.chr2:165952053T>C	ENST00000360093.3	-	25	4890	c.4399A>G	c.(4399-4401)Atc>Gtc	p.I1467V	SCN3A_ENST00000409101.3_Missense_Mutation_p.I1418V|SCN3A_ENST00000283254.7_Missense_Mutation_p.I1467V	NM_001081677.1	NP_001075146.1	Q9NY46	SCN3A_HUMAN	sodium channel, voltage-gated, type III, alpha subunit	1467						voltage-gated sodium channel complex	voltage-gated sodium channel activity			NS(1)|breast(7)|central_nervous_system(2)|endometrium(10)|haematopoietic_and_lymphoid_tissue(1)|kidney(5)|large_intestine(19)|liver(2)|lung(47)|ovary(6)|prostate(3)|skin(10)|upper_aerodigestive_tract(4)|urinary_tract(3)	120					Lamotrigine(DB00555)	TTATCTATGATGACACCAATG	0.333000													29	46					0	0	1	0	0
JHDM1D	0	broad.mit.edu	37	7	139790982	139790982	+	Missense_Mutation	SNP	C	C	T			TCGA-2A-AAYF-01A-11D-A41K-08	TCGA-2A-AAYF-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5d4f8ba6-7ff3-40ec-af29-7b3450f813a2	b4ade944-957e-4ec1-a880-e330b8de3980	g.chr7:139790982C>T	ENST00000397560.2	-	20	2835	c.2738G>A	c.(2737-2739)cGt>cAt	p.R913H		NM_030647.1	NP_085150.1	Q6ZMT4	KDM7_HUMAN		913					midbrain development|transcription, DNA-dependent	nucleolus	histone demethylase activity (H3-K27 specific)|histone demethylase activity (H3-K36 specific)|histone demethylase activity (H3-K9 specific)|histone demethylase activity (H4-K20 specific)|iron ion binding|methylated histone residue binding|oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen|zinc ion binding	p.R913H(1)		central_nervous_system(2)|endometrium(4)|kidney(1)|large_intestine(1)|lung(10)|ovary(1)|prostate(1)|skin(1)|stomach(1)	22	Melanoma(164;0.0142)					TTTTTTTGGACGTTTACCTAT	0.423000													18	25					0	0	1	0	0
CHEK2	11200	broad.mit.edu	37	22	29091841	29091841	+	Silent	SNP	G	G	A	rs146546850	byFrequency	TCGA-2A-AAYF-01A-11D-A41K-08	TCGA-2A-AAYF-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5d4f8ba6-7ff3-40ec-af29-7b3450f813a2	b4ade944-957e-4ec1-a880-e330b8de3980	g.chr22:29091841G>A	ENST00000544772.1	-	12	1889	c.453C>T	c.(451-453)tcC>tcT	p.S151S	CHEK2_ENST00000382580.2_Silent_p.S415S|CHEK2_ENST00000382566.1_3'UTR|CHEK2_ENST00000404276.1_Silent_p.S372S|CHEK2_ENST00000382565.1_Intron|CHEK2_ENST00000328354.6_Silent_p.S372S|CHEK2_ENST00000402731.1_Silent_p.S343S|CHEK2_ENST00000348295.3_Silent_p.S343S|CHEK2_ENST00000405598.1_Silent_p.S372S|CHEK2_ENST00000403642.1_Silent_p.S281S|CHEK2_ENST00000382578.1_Silent_p.S281S	NM_001257387.1	NP_001244316.1	O96017	CHK2_HUMAN	checkpoint kinase 2	372	FHA.				cell cycle|DNA damage checkpoint|DNA damage response, signal transduction resulting in induction of apoptosis|replicative senescence	PML body	ATP binding|metal ion binding|protein binding|protein serine/threonine kinase activity	p.S372S(8)		central_nervous_system(17)|endometrium(2)|kidney(11)|large_intestine(2)|lung(11)|ovary(1)|prostate(4)|stomach(2)	50						CCAAAATCTTGGAGTGCCCAA	0.413000			F			breast		Direct reversal of damage;Other conserved DNA damage response genes					4	50					0	0	1	0	0
WASF1	8936	broad.mit.edu	37	6	110426721	110426721	+	Missense_Mutation	SNP	C	C	T			TCGA-2A-AAYF-01A-11D-A41K-08	TCGA-2A-AAYF-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5d4f8ba6-7ff3-40ec-af29-7b3450f813a2	b4ade944-957e-4ec1-a880-e330b8de3980	g.chr6:110426721C>T	ENST00000392589.1	-	8	1438	c.602G>A	c.(601-603)cGg>cAg	p.R201Q	WASF1_ENST00000392587.2_Missense_Mutation_p.R201Q|WASF1_ENST00000359451.2_Missense_Mutation_p.R201Q|WASF1_ENST00000392586.1_Missense_Mutation_p.R201Q|WASF1_ENST00000392588.1_Missense_Mutation_p.R201Q	NM_003931.2	NP_003922.1	Q92558	WASF1_HUMAN	WAS protein family, member 1	201					actin filament polymerization|cellular component movement	actin cytoskeleton	actin binding			breast(1)|central_nervous_system(1)|kidney(2)|large_intestine(3)|lung(7)|skin(1)|upper_aerodigestive_tract(1)	16		all_cancers(87;1.18e-05)|Acute lymphoblastic leukemia(125;2.66e-08)|all_hematologic(75;1.13e-06)|all_epithelial(87;0.00159)|Colorectal(196;0.0488)		OV - Ovarian serous cystadenocarcinoma(136;0.0364)|Epithelial(106;0.051)|all cancers(137;0.0687)		CCATTCTCGCCGCCTGTCATG	0.448000													25	51					0	0	1	0	0
NSMAF	8439	broad.mit.edu	37	8	59508192	59508192	+	Missense_Mutation	SNP	C	C	T			TCGA-2A-AAYF-01A-11D-A41K-08	TCGA-2A-AAYF-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5d4f8ba6-7ff3-40ec-af29-7b3450f813a2	b4ade944-957e-4ec1-a880-e330b8de3980	g.chr8:59508192C>T	ENST00000038176.3	-	22	2031	c.1819G>A	c.(1819-1821)Gaa>Aaa	p.E607K	NSMAF_ENST00000427130.2_Missense_Mutation_p.E638K	NM_003580.3	NP_003571.2	Q92636	FAN_HUMAN	neutral sphingomyelinase (N-SMase) activation associated factor	607					ceramide metabolic process	cytoplasm|soluble fraction	protein binding|receptor signaling protein activity			autonomic_ganglia(1)|central_nervous_system(1)|endometrium(7)|kidney(3)|large_intestine(7)|lung(11)|ovary(1)|pancreas(1)|prostate(2)|skin(3)|urinary_tract(1)	38		all_lung(136;0.174)|Lung NSC(129;0.2)				TTGCTTTCTTCGGTCAGGTCT	0.388000													21	50					0	0	1	0	0
GRM2	2912	broad.mit.edu	37	3	51746586	51746586	+	Missense_Mutation	SNP	G	G	A			TCGA-2A-AAYF-01A-11D-A41K-08	TCGA-2A-AAYF-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5d4f8ba6-7ff3-40ec-af29-7b3450f813a2	b4ade944-957e-4ec1-a880-e330b8de3980	g.chr3:51746586G>A	ENST00000395052.3	+	3	782	c.548G>A	c.(547-549)cGc>cAc	p.R183H	GRM2_ENST00000442933.2_Missense_Mutation_p.R183H|GRM2_ENST00000475478.1_Intron	NM_000839.3	NP_000830.2	Q14416	GRM2_HUMAN	glutamate receptor, metabotropic 2	183					synaptic transmission	integral to plasma membrane		p.R183H(1)		breast(1)|endometrium(6)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(5)|liver(1)|lung(11)|prostate(2)|skin(2)|stomach(1)|upper_aerodigestive_tract(1)	33				BRCA - Breast invasive adenocarcinoma(193;8.01e-05)|Kidney(197;0.000539)|KIRC - Kidney renal clear cell carcinoma(197;0.000716)	Acamprosate(DB00659)|Nicotine(DB00184)	TACTTTGCCCGCACAGTGCCT	0.542000													5	136					0	0	1	0	0
CELSR3	1951	broad.mit.edu	37	3	48679866	48679866	+	Missense_Mutation	SNP	C	C	T			TCGA-2A-AAYF-01A-11D-A41K-08	TCGA-2A-AAYF-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5d4f8ba6-7ff3-40ec-af29-7b3450f813a2	b4ade944-957e-4ec1-a880-e330b8de3980	g.chr3:48679866C>T	ENST00000544264.1	-	32	8885	c.8605G>A	c.(8605-8607)Gac>Aac	p.D2869N	CELSR3_ENST00000164024.4_Missense_Mutation_p.D2864N			Q9NYQ7	CELR3_HUMAN	cadherin, EGF LAG seven-pass G-type receptor 3	2864					homophilic cell adhesion|multicellular organismal development|neuropeptide signaling pathway	integral to membrane|plasma membrane	calcium ion binding|G-protein coupled receptor activity|protein binding			NS(1)|biliary_tract(1)|breast(2)|central_nervous_system(3)|cervix(1)|endometrium(10)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(7)|lung(23)|ovary(9)|prostate(6)|skin(7)|stomach(1)|upper_aerodigestive_tract(3)|urinary_tract(5)	83				BRCA - Breast invasive adenocarcinoma(193;0.000292)|KIRC - Kidney renal clear cell carcinoma(197;0.00549)|Kidney(197;0.00619)		TCAGTGTGGTCAGCGGCTGAG	0.622000													7	19					0	0	1	0	0
LIMCH1	22998	broad.mit.edu	37	4	41621368	41621368	+	Silent	SNP	G	G	A	rs139697872		TCGA-2A-AAYF-01A-11D-A41K-08	TCGA-2A-AAYF-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5d4f8ba6-7ff3-40ec-af29-7b3450f813a2	b4ade944-957e-4ec1-a880-e330b8de3980	g.chr4:41621368G>A	ENST00000313860.7	+	8	900	c.846G>A	c.(844-846)gcG>gcA	p.A282A	LIMCH1_ENST00000513024.1_Silent_p.A123A|LIMCH1_ENST00000509638.1_Silent_p.A123A|LIMCH1_ENST00000508501.1_Silent_p.A282A|LIMCH1_ENST00000503057.1_Silent_p.A123A|LIMCH1_ENST00000509277.1_Silent_p.A128A|LIMCH1_ENST00000509454.1_Silent_p.A130A|LIMCH1_ENST00000512820.1_Silent_p.A282A|LIMCH1_ENST00000514096.1_Silent_p.A135A|LIMCH1_ENST00000512632.1_Silent_p.A282A|LIMCH1_ENST00000381753.4_Silent_p.A128A|LIMCH1_ENST00000511496.1_Silent_p.A123A|LIMCH1_ENST00000512946.1_Silent_p.A282A|LIMCH1_ENST00000396595.3_Silent_p.A128A	NM_014988.2	NP_055803.2	Q9UPQ0	LIMC1_HUMAN	LIM and calponin homology domains 1	282					actomyosin structure organization		actin binding|zinc ion binding			central_nervous_system(2)|endometrium(1)|large_intestine(9)|lung(17)|ovary(3)|pancreas(1)|prostate(3)|skin(5)	41						ACGTCCCCGCGCCTCTGAGAA	0.577000													21	43					0	0	1	0	0
LINC00478	0	broad.mit.edu	37	21	17566914	17566914	+	RNA	SNP	A	A	G			TCGA-2A-AAYF-01A-11D-A41K-08	TCGA-2A-AAYF-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5d4f8ba6-7ff3-40ec-af29-7b3450f813a2	b4ade944-957e-4ec1-a880-e330b8de3980	g.chr21:17566914A>G	ENST00000458468.1	+	0	409					NR_027790.1																						GGGGCAGAAAATAGCACACTT	0.403000													14	32					0	0	1	0	0
UTP20	27340	broad.mit.edu	37	12	101757394	101757394	+	Missense_Mutation	SNP	A	A	G			TCGA-2A-AAYF-01A-11D-A41K-08	TCGA-2A-AAYF-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5d4f8ba6-7ff3-40ec-af29-7b3450f813a2	b4ade944-957e-4ec1-a880-e330b8de3980	g.chr12:101757394A>G	ENST00000261637.4	+	45	6005	c.5831A>G	c.(5830-5832)aAg>aGg	p.K1944R		NM_014503.2	NP_055318.2	O75691	UTP20_HUMAN	UTP20, small subunit (SSU) processome component, homolog (yeast)	1944					endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)|endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)|endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)|negative regulation of cell proliferation	90S preribosome|cytoplasm|nucleolus|nucleoplasm|preribosome, small subunit precursor|small-subunit processome	protein binding			NS(3)|biliary_tract(1)|breast(3)|central_nervous_system(1)|cervix(1)|endometrium(9)|kidney(2)|large_intestine(26)|lung(30)|ovary(2)|prostate(3)|skin(1)|stomach(2)|upper_aerodigestive_tract(2)|urinary_tract(2)	88						GCTGAAGAGAAGGAAGTAAAG	0.393000													18	34					0	0	1	0	0
CHEK2	11200	broad.mit.edu	37	22	29091840	29091840	+	Missense_Mutation	SNP	T	T	C	rs142470496	byFrequency	TCGA-2A-AAYF-01A-11D-A41K-08	TCGA-2A-AAYF-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5d4f8ba6-7ff3-40ec-af29-7b3450f813a2	b4ade944-957e-4ec1-a880-e330b8de3980	g.chr22:29091840T>C	ENST00000544772.1	-	12	1890	c.454A>G	c.(454-456)Aag>Gag	p.K152E	CHEK2_ENST00000382580.2_Missense_Mutation_p.K416E|CHEK2_ENST00000382566.1_3'UTR|CHEK2_ENST00000404276.1_Missense_Mutation_p.K373E|CHEK2_ENST00000382565.1_Intron|CHEK2_ENST00000328354.6_Missense_Mutation_p.K373E|CHEK2_ENST00000402731.1_Missense_Mutation_p.K344E|CHEK2_ENST00000348295.3_Missense_Mutation_p.K344E|CHEK2_ENST00000405598.1_Missense_Mutation_p.K373E|CHEK2_ENST00000403642.1_Missense_Mutation_p.K282E|CHEK2_ENST00000382578.1_Missense_Mutation_p.K282E	NM_001257387.1	NP_001244316.1	O96017	CHK2_HUMAN	checkpoint kinase 2	373	FHA.				cell cycle|DNA damage checkpoint|DNA damage response, signal transduction resulting in induction of apoptosis|replicative senescence	PML body	ATP binding|metal ion binding|protein binding|protein serine/threonine kinase activity	p.K373E(9)		central_nervous_system(17)|endometrium(2)|kidney(11)|large_intestine(2)|lung(11)|ovary(1)|prostate(4)|stomach(2)	50						CCCAAAATCTTGGAGTGCCCA	0.418000			F			breast		Direct reversal of damage;Other conserved DNA damage response genes					4	54					0	0	1	0	0
ZFHX4	79776	broad.mit.edu	37	8	77767702	77767702	+	Missense_Mutation	SNP	C	C	T			TCGA-2A-AAYF-01A-11D-A41K-08	TCGA-2A-AAYF-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5d4f8ba6-7ff3-40ec-af29-7b3450f813a2	b4ade944-957e-4ec1-a880-e330b8de3980	g.chr8:77767702C>T	ENST00000521891.2	+	10	8993	c.8545C>T	c.(8545-8547)Cca>Tca	p.P2849S	ZFHX4_ENST00000050961.6_Missense_Mutation_p.P2804S|ZFHX4_ENST00000455469.2_Missense_Mutation_p.P2804S|ZFHX4_ENST00000518282.1_Missense_Mutation_p.P2823S	NM_024721.4	NP_078997.4	Q86UP3	ZFHX4_HUMAN	zinc finger homeobox 4	2804						nucleus	sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity|zinc ion binding			NS(3)|breast(11)|central_nervous_system(1)|endometrium(36)|haematopoietic_and_lymphoid_tissue(2)|kidney(15)|large_intestine(66)|liver(2)|lung(245)|ovary(11)|pancreas(3)|prostate(11)|skin(7)|upper_aerodigestive_tract(13)|urinary_tract(6)	432			BRCA - Breast invasive adenocarcinoma(89;0.0895)			GGATACTCTGCCAAAACCTGC	0.488000										HNSCC(33;0.089)			13	21					0	0	1	0	0
WDR7	23335	broad.mit.edu	37	18	54339808	54339808	+	Missense_Mutation	SNP	G	G	T			TCGA-2A-AAYF-01A-11D-A41K-08	TCGA-2A-AAYF-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5d4f8ba6-7ff3-40ec-af29-7b3450f813a2	b4ade944-957e-4ec1-a880-e330b8de3980	g.chr18:54339808G>T	ENST00000254442.3	+	2	273	c.62G>T	c.(61-63)tGc>tTc	p.C21F	WDR7_ENST00000589935.1_Intron|WDR7_ENST00000357574.3_Missense_Mutation_p.C21F	NM_015285.2	NP_056100.2	Q9Y4E6	WDR7_HUMAN	WD repeat domain 7	21										NS(1)|breast(5)|cervix(1)|endometrium(6)|kidney(2)|large_intestine(14)|lung(37)|ovary(3)|prostate(2)|skin(4)|upper_aerodigestive_tract(3)	78				Lung(128;0.0238)|Colorectal(16;0.0296)		CCCACACATTGCATCTCAGCC	0.433000													25	64					3.17567e-06	3.34281e-06	1	1	0
AEBP1	165	broad.mit.edu	37	7	44146386	44146386	+	Silent	SNP	G	G	A	rs144974496		TCGA-2A-AAYF-01A-11D-A41K-08	TCGA-2A-AAYF-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5d4f8ba6-7ff3-40ec-af29-7b3450f813a2	b4ade944-957e-4ec1-a880-e330b8de3980	g.chr7:44146386G>A	ENST00000223357.3	+	2	800	c.495G>A	c.(493-495)ccG>ccA	p.P165P		NM_001129.3	NP_001120.3	Q8IUX7	AEBP1_HUMAN	AE binding protein 1	165	Pro-rich.				cell adhesion|muscle organ development|proteolysis|skeletal system development	cytoplasm|extracellular space|nucleus	DNA binding|metallocarboxypeptidase activity|sequence-specific DNA binding transcription factor activity|zinc ion binding			NS(1)|breast(1)|cervix(2)|endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(8)|lung(13)|upper_aerodigestive_tract(2)	33						AGAAGCCCCCGTCAGGGAAGA	0.652000													8	7					0	0	1	0	0
UIMC1	51720	broad.mit.edu	37	5	176395642	176395642	+	Missense_Mutation	SNP	T	T	C			TCGA-2A-AAYF-01A-11D-A41K-08	TCGA-2A-AAYF-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5d4f8ba6-7ff3-40ec-af29-7b3450f813a2	b4ade944-957e-4ec1-a880-e330b8de3980	g.chr5:176395642T>C	ENST00000377219.2	-	6	1280	c.1114A>G	c.(1114-1116)Aaa>Gaa	p.K372E	UIMC1_ENST00000503273.1_5'UTR|UIMC1_ENST00000377227.4_Missense_Mutation_p.K372E|UIMC1_ENST00000506128.1_Intron|UIMC1_ENST00000511320.1_Missense_Mutation_p.K372E	NM_016290.4	NP_057374.3	Q96RL1	UIMC1_HUMAN	ubiquitin interaction motif containing 1	372	AIR.				double-strand break repair|G2/M transition DNA damage checkpoint|histone H2A K63-linked deubiquitination|negative regulation of transcription, DNA-dependent|positive regulation of DNA repair|response to ionizing radiation|transcription, DNA-dependent	BRCA1-A complex	histone binding|K63-linked polyubiquitin binding			NS(1)|endometrium(2)|kidney(3)|large_intestine(3)|lung(5)|ovary(4)|pancreas(1)|prostate(1)|skin(1)	21	all_cancers(89;7.96e-05)|Renal(175;0.000269)|Lung NSC(126;0.00476)|all_lung(126;0.00806)	Medulloblastoma(196;0.0145)|all_neural(177;0.0325)	Kidney(164;2.23e-05)|KIRC - Kidney renal clear cell carcinoma(164;0.000178)			TCCTTGGTTTTTGAGTGCCAG	0.443000													54	85					0	0	1	0	0
AC024560.3	0	broad.mit.edu	37	3	197348739	197348739	+	RNA	SNP	G	G	C			TCGA-2A-AAYF-01A-11D-A41K-08	TCGA-2A-AAYF-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5d4f8ba6-7ff3-40ec-af29-7b3450f813a2	b4ade944-957e-4ec1-a880-e330b8de3980	g.chr3:197348739G>C	ENST00000418868.1	-	0	520					NR_003266.2																						TAATTTTCTAGCTGTGAAAGA	0.398000													6	86					0	0	1	0	0
FOXG1	2290	broad.mit.edu	37	14	29237877	29237877	+	Silent	SNP	G	G	A			TCGA-2A-AAYF-01A-11D-A41K-08	TCGA-2A-AAYF-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5d4f8ba6-7ff3-40ec-af29-7b3450f813a2	b4ade944-957e-4ec1-a880-e330b8de3980	g.chr14:29237877G>A	ENST00000382535.3	+	2	1761	c.1392G>A	c.(1390-1392)acG>acA	p.T464T	FOXG1_ENST00000313071.4_Silent_p.T464T			P55316	FOXG1_HUMAN	forkhead box G1	464					axon midline choice point recognition|central nervous system neuron development|dorsal/ventral pattern formation|embryo development ending in birth or egg hatching|hindbrain development|inner ear morphogenesis|negative regulation of neuron differentiation|negative regulation of transcription, DNA-dependent|nonmotile primary cilium assembly|nose development|positive regulation of cell cycle|positive regulation of neuroblast proliferation|positive regulation of transcription from RNA polymerase II promoter|regulation of mitotic cell cycle|regulation of sequence-specific DNA binding transcription factor activity|tissue development	transcription factor complex	DNA bending activity|double-stranded DNA binding|promoter binding|sequence-specific DNA binding|sequence-specific enhancer binding RNA polymerase II transcription factor activity|specific RNA polymerase II transcription factor activity|specific transcriptional repressor activity|transcription activator activity|transcription factor binding			breast(1)|central_nervous_system(1)|endometrium(2)|large_intestine(9)|lung(23)|ovary(2)|pancreas(1)|prostate(1)|skin(1)|urinary_tract(2)	43			LUAD - Lung adenocarcinoma(48;0.011)|Lung(238;0.0575)	GBM - Glioblastoma multiforme(265;0.00413)		CAAGTTTTACGACGGGACTGT	0.547000													52	69					0	0	1	0	0
SNTB1	6641	broad.mit.edu	37	8	121823566	121823566	+	Missense_Mutation	SNP	T	T	C			TCGA-2A-AAYF-01A-11D-A41K-08	TCGA-2A-AAYF-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5d4f8ba6-7ff3-40ec-af29-7b3450f813a2	b4ade944-957e-4ec1-a880-e330b8de3980	g.chr8:121823566T>C	ENST00000395601.3	-	2	932	c.518A>G	c.(517-519)cAc>cGc	p.H173R	SNTB1_ENST00000517992.1_Missense_Mutation_p.H173R|SNTB1_ENST00000519177.1_5'UTR	NM_021021.3	NP_066301.1	Q13884	SNTB1_HUMAN	syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)	173	PDZ.|PH 1.				muscle contraction	cell junction|cytoplasm|cytoskeleton|dystrophin-associated glycoprotein complex|sarcolemma	actin binding|calmodulin binding			NS(1)|endometrium(2)|kidney(1)|large_intestine(2)|lung(10)|prostate(2)|skin(6)	24	Lung NSC(37;4.46e-09)|Ovarian(258;0.0254)|Hepatocellular(40;0.0997)		STAD - Stomach adenocarcinoma(47;0.00503)			CGCCTCGTCGTGGGTGGCGTC	0.692000													36	51					0	0	1	0	0
MYPN	84665	broad.mit.edu	37	10	69961683	69961683	+	Silent	SNP	C	C	T			TCGA-2A-AAYF-01A-11D-A41K-08	TCGA-2A-AAYF-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5d4f8ba6-7ff3-40ec-af29-7b3450f813a2	b4ade944-957e-4ec1-a880-e330b8de3980	g.chr10:69961683C>T	ENST00000358913.5	+	18	4079	c.3591C>T	c.(3589-3591)ggC>ggT	p.G1197G	MYPN_ENST00000354393.2_Silent_p.G922G|MYPN_ENST00000540630.1_Silent_p.G1197G	NM_001256267.1|NM_032578.3	NP_001243196.1|NP_115967.2	Q86TC9	MYPN_HUMAN	myopalladin	1197	Ig-like 5.|Interaction with ACTN.					nucleus|sarcomere	actin binding			breast(2)|central_nervous_system(1)|endometrium(13)|kidney(6)|large_intestine(13)|liver(1)|lung(43)|ovary(3)|prostate(1)|skin(6)|upper_aerodigestive_tract(5)	94						GCGTGATAGGCATGCCCCCAC	0.562000													36	47					0	0	1	0	0
TTN	7273	broad.mit.edu	37	2	179580332	179580332	+	Silent	SNP	C	C	T			TCGA-2A-AAYF-01A-11D-A41K-08	TCGA-2A-AAYF-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5d4f8ba6-7ff3-40ec-af29-7b3450f813a2	b4ade944-957e-4ec1-a880-e330b8de3980	g.chr2:179580332C>T	ENST00000589042.1	-	89	26033	c.25809G>A	c.(25807-25809)tcG>tcA	p.S8603S	TTN_ENST00000359218.5_Intron|TTN_ENST00000342992.6_Silent_p.S7359S|TTN_ENST00000460472.2_Intron|TTN_ENST00000342175.6_Intron|TTN_ENST00000591111.1_Silent_p.S8286S|TTN-AS1_ENST00000585451.1_RNA	NM_001267550.1	NP_001254479.1	Q8WZ42	TITIN_HUMAN	titin	8286	Ig-like 68.						ATP binding|nucleic acid binding|protein serine/threonine kinase activity|protein tyrosine kinase activity			NS(24)|autonomic_ganglia(1)|breast(64)|central_nervous_system(14)|cervix(14)|endometrium(96)|haematopoietic_and_lymphoid_tissue(16)|kidney(91)|large_intestine(303)|liver(1)|lung(595)|ovary(58)|pancreas(17)|prostate(38)|skin(60)|stomach(29)|upper_aerodigestive_tract(1)|urinary_tract(26)	1448			OV - Ovarian serous cystadenocarcinoma(117;0.023)|Epithelial(96;0.0454)|all cancers(119;0.134)			GCACAGCCACCGAGTCAACGA	0.468000													17	28					0	0	1	0	0
MUC5AC	4586	broad.mit.edu	37	11	1159382	1159382	+	Silent	SNP	C	C	T			TCGA-2A-AAYF-01A-11D-A41K-08	TCGA-2A-AAYF-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5d4f8ba6-7ff3-40ec-af29-7b3450f813a2	b4ade944-957e-4ec1-a880-e330b8de3980	g.chr11:1159382C>T	ENST00000356191.2	+	16	1350	c.1350C>T	c.(1348-1350)caC>caT	p.H450H						mucin 5AC, oligomeric mucus/gel-forming											NS(1)|breast(2)|central_nervous_system(7)|cervix(2)|endometrium(36)|haematopoietic_and_lymphoid_tissue(5)|kidney(9)|large_intestine(19)|liver(1)|lung(89)|ovary(7)|prostate(8)|skin(9)|stomach(1)|upper_aerodigestive_tract(6)|urinary_tract(1)	203		all_cancers(49;2.94e-05)|Breast(177;0.00257)|all_epithelial(84;0.00314)|Ovarian(85;0.0228)|Medulloblastoma(188;0.0321)|all_neural(188;0.0762)		BRCA - Breast invasive adenocarcinoma(625;0.00146)|Lung(200;0.0612)|LUSC - Lung squamous cell carcinoma(625;0.0724)		ACACGGTGCACGGCGACTGCA	0.662000													31	48					0	0	1	0	0
ZC3H3	23144	broad.mit.edu	37	8	144522387	144522389	+	In_Frame_Del	DEL	GAG	GAG	-	rs2272753	byFrequency	TCGA-2A-AAYF-01A-11D-A41K-08	TCGA-2A-AAYF-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5d4f8ba6-7ff3-40ec-af29-7b3450f813a2	b4ade944-957e-4ec1-a880-e330b8de3980	g.chr8:144522387_144522389delGAG	ENST00000262577.5	-	11	2668_2670	c.2637_2639delCTC	c.(2635-2640)tca>tc	p.SS879del		NM_015117.2	NP_055932.2	Q8IXZ2	ZC3H3_HUMAN	zinc finger CCCH-type containing 3	879	Poly-Ser.				mRNA polyadenylation|poly(A)+ mRNA export from nucleus|regulation of mRNA export from nucleus	nucleus	nucleic acid binding|zinc ion binding			breast(1)|endometrium(2)|kidney(2)|large_intestine(1)|lung(13)|ovary(1)|skin(2)|upper_aerodigestive_tract(1)	23	all_cancers(97;8.64e-11)|all_epithelial(106;6.43e-09)|Lung NSC(106;0.000202)|all_lung(105;0.000548)|Ovarian(258;0.0212)|Acute lymphoblastic leukemia(118;0.155)		Colorectal(110;0.107)|BRCA - Breast invasive adenocarcinoma(115;0.107)			Gggaggggatgaggaggaggagg	0.655													2	4	---	---	---	---					
SETD8	387893	broad.mit.edu	37	12	123879653	123879653	+	Frame_Shift_Del	DEL	A	A	-			TCGA-2A-AAYF-01A-11D-A41K-08	TCGA-2A-AAYF-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5d4f8ba6-7ff3-40ec-af29-7b3450f813a2	b4ade944-957e-4ec1-a880-e330b8de3980	g.chr12:123879653delA	ENST00000402868.3	+	4	775	c.349delA	c.(349-351)aafs	p.K117fs	SETD8_ENST00000478781.2_3'UTR|SETD8_ENST00000330479.4_Frame_Shift_Del_p.K117fs			Q9NQR1	SETD8_HUMAN	SET domain containing (lysine methyltransferase) 8	158					cell division|mitosis|negative regulation of transcription from RNA polymerase II promoter|peptidyl-lysine monomethylation|regulation of DNA damage response, signal transduction by p53 class mediator|transcription, DNA-dependent	chromosome|nucleus	histone-lysine N-methyltransferase activity|p53 binding|transcription corepressor activity			central_nervous_system(1)|endometrium(1)|large_intestine(3)|lung(4)|prostate(3)|urinary_tract(1)	13	all_neural(191;0.101)|Medulloblastoma(191;0.163)			OV - Ovarian serous cystadenocarcinoma(86;0.00101)|Epithelial(86;0.00425)		ACAGAAGATCAAAGACGCCAG	0.502													2	4	---	---	---	---					
CORO2B	10391	broad.mit.edu	37	15	68937526	68937541	+	Frame_Shift_Del	DEL	TCCAAGTTCCGGAATG	TCCAAGTTCCGGAATG	-			TCGA-2A-AAYF-01A-11D-A41K-08	TCGA-2A-AAYF-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5d4f8ba6-7ff3-40ec-af29-7b3450f813a2	b4ade944-957e-4ec1-a880-e330b8de3980	g.chr15:68937526_68937541delTCCAAGTTCCGGAATG	ENST00000543950.1	+	2	382_397	c.28_43delTCCAAGTTCCGGAATG	c.(28-45)tcfs	p.SKFRNV10fs	CORO2B_ENST00000540068.1_Frame_Shift_Del_p.SKFRNV10fs|CORO2B_ENST00000566799.1_Frame_Shift_Del_p.SKFRNV15fs|CORO2B_ENST00000261861.5_Frame_Shift_Del_p.SKFRNV10fs	NM_001190457.1	NP_001177386.1	Q9UQ03	COR2B_HUMAN	coronin, actin binding protein, 2B	15					actin cytoskeleton organization	actin cytoskeleton|cytoplasm|membrane	actin filament binding	p.R18Q(1)		kidney(3)|large_intestine(13)|lung(11)|ovary(3)|skin(2)|upper_aerodigestive_tract(1)|urinary_tract(3)	36						ATACCGTAGCTCCAAGTTCCGGAATGTCTACGGGAA	0.611													5	9	---	---	---	---					
ABCC6P1	0	broad.mit.edu	37	16	18593648	18593649	+	RNA	INS	-	-	A			TCGA-2A-AAYF-01A-11D-A41K-08	TCGA-2A-AAYF-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5d4f8ba6-7ff3-40ec-af29-7b3450f813a2	b4ade944-957e-4ec1-a880-e330b8de3980	g.chr16:18593648_18593649insA	ENST00000546162.2	+	0	805					NR_003569.1																						accctgtctcgaaaaaaaaaaa	0.505													3	5	---	---	---	---