Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
SAMD9L	219285	broad.mit.edu	37	7	92764069	92764069	+	Nonsense_Mutation	SNP	G	G	A	rs150070697	byFrequency	TCGA-EJ-A46E-01A-31D-A257-08	TCGA-EJ-A46E-10A-01D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3471f90f-e293-45d1-a6cf-4927be485fd9	757ae720-46cc-4388-a24f-5c8ab52e12f4	g.chr7:92764069G>A	ENST00000318238.4	-	5	2432	c.1216C>T	c.(1216-1218)Cga>Tga	p.R406*	SAMD9L_ENST00000437805.1_Nonsense_Mutation_p.R406*|SAMD9L_ENST00000411955.1_Nonsense_Mutation_p.R406*	NM_152703.2	NP_689916.2	Q8IVG5	SAM9L_HUMAN	sterile alpha motif domain containing 9-like	406										central_nervous_system(1)|endometrium(8)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(23)|liver(2)|lung(31)|ovary(5)|prostate(2)|skin(6)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(4)	88	all_cancers(62;4.15e-11)|all_epithelial(64;2.29e-10)|Breast(17;0.000675)|Lung NSC(181;0.0755)|all_lung(186;0.0989)		STAD - Stomach adenocarcinoma(171;0.000302)			AGTGAGTCTCGGTTTCCTATG	0.353000													13	174					0	0	1	0	0
FRG1B	0	broad.mit.edu	37	20	29625971	29625971	+	Missense_Mutation	SNP	C	C	A	rs145033899		TCGA-EJ-A46E-01A-31D-A257-08	TCGA-EJ-A46E-10A-01D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3471f90f-e293-45d1-a6cf-4927be485fd9	757ae720-46cc-4388-a24f-5c8ab52e12f4	g.chr20:29625971C>A	ENST00000278882.3	+	5	595	c.215C>A	c.(214-216)cCa>cAa	p.P72Q	FRG1B_ENST00000358464.4_Missense_Mutation_p.P72Q|FRG1B_ENST00000439954.2_Missense_Mutation_p.P77Q																endometrium(10)|kidney(21)|lung(3)|pancreas(1)|prostate(9)|urinary_tract(9)	53						CAATGGGAACCAGTCTTTCAA	0.328000													6	102					0.00198382	0.00213077	1	1	0
SYT13	57586	broad.mit.edu	37	11	45274253	45274253	+	Missense_Mutation	SNP	C	C	T			TCGA-EJ-A46E-01A-31D-A257-08	TCGA-EJ-A46E-10A-01D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3471f90f-e293-45d1-a6cf-4927be485fd9	757ae720-46cc-4388-a24f-5c8ab52e12f4	g.chr11:45274253C>T	ENST00000020926.3	-	4	676	c.565G>A	c.(565-567)Gga>Aga	p.G189R		NM_001247987.1|NM_020826.2	NP_001234916.1|NP_065877.1	Q7L8C5	SYT13_HUMAN	synaptotagmin XIII	189	C2 1.					transport vesicle				breast(1)|large_intestine(3)|lung(16)|ovary(1)|skin(2)	23						TCACAGCCTCCGTCGTGGTTG	0.602000											OREG0020928	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	4	79					0	0	1	0	0
STEAP2	261729	broad.mit.edu	37	7	89856643	89856643	+	Missense_Mutation	SNP	A	A	G	rs138124501	byFrequency	TCGA-EJ-A46E-01A-31D-A257-08	TCGA-EJ-A46E-10A-01D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3471f90f-e293-45d1-a6cf-4927be485fd9	757ae720-46cc-4388-a24f-5c8ab52e12f4	g.chr7:89856643A>G	ENST00000287908.3	+	3	1244	c.851A>G	c.(850-852)tAc>tGc	p.Y284C	STEAP2_ENST00000394621.2_Missense_Mutation_p.Y284C|STEAP2_ENST00000394632.1_Missense_Mutation_p.Y284C|STEAP2_ENST00000402625.2_Missense_Mutation_p.Y284C|STEAP2_ENST00000394629.2_Missense_Mutation_p.Y284C|STEAP2_ENST00000394622.2_Missense_Mutation_p.Y284C|STEAP2_ENST00000394626.1_Missense_Mutation_p.Y284C	NM_001244944.1|NM_152999.3	NP_001231873.1|NP_694544.2	Q8NFT2	STEA2_HUMAN	STEAP family member 2, metalloreductase	284	Ferric oxidoreductase.				electron transport chain|endocytosis|Golgi to plasma membrane transport|ion transport|iron ion homeostasis|regulated secretory pathway|response to hormone stimulus	cytosol|early endosome|endosome membrane|integral to Golgi membrane|plasma membrane|trans-Golgi network transport vesicle|vesicular fraction	electron carrier activity|flavin adenine dinucleotide binding|iron ion binding|oxidoreductase activity|transporter activity			endometrium(1)|haematopoietic_and_lymphoid_tissue(2)|kidney(1)|large_intestine(2)|lung(5)|ovary(2)|prostate(1)|skin(1)	15	all_hematologic(106;0.112)					CAACTTTATTACGGCACCAAG	0.408000													8	85					0	0	1	0	0
FLNB	2317	broad.mit.edu	37	3	58062900	58062900	+	Silent	SNP	G	G	A			TCGA-EJ-A46E-01A-31D-A257-08	TCGA-EJ-A46E-10A-01D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3471f90f-e293-45d1-a6cf-4927be485fd9	757ae720-46cc-4388-a24f-5c8ab52e12f4	g.chr3:58062900G>A	ENST00000357272.4	+	2	585	c.420G>A	c.(418-420)acG>acA	p.T140T	FLNB_ENST00000348383.5_Silent_p.T140T|FLNB_ENST00000295956.4_Silent_p.T140T|FLNB_ENST00000429972.2_Silent_p.T140T|FLNB_ENST00000358537.3_Silent_p.T140T|FLNB_ENST00000490882.1_Silent_p.T140T			O75369	FLNB_HUMAN	filamin B, beta	140	Actin-binding.|CH 2.				actin cytoskeleton organization|cell differentiation|cytoskeletal anchoring at plasma membrane|signal transduction	cell cortex|integral to membrane|nucleus|sarcomere	actin binding			NS(1)|breast(13)|central_nervous_system(2)|endometrium(10)|haematopoietic_and_lymphoid_tissue(2)|kidney(4)|large_intestine(23)|liver(2)|lung(38)|ovary(6)|prostate(3)|skin(8)|upper_aerodigestive_tract(3)|urinary_tract(5)	120				BRCA - Breast invasive adenocarcinoma(55;0.000335)|KIRC - Kidney renal clear cell carcinoma(284;0.0726)|Kidney(284;0.0898)		AGAAGCAGACGCCAAAGCAGA	0.557000													4	76					0	0	1	0	0
COL5A3	50509	broad.mit.edu	37	19	10088375	10088375	+	Silent	SNP	G	G	T			TCGA-EJ-A46E-01A-31D-A257-08	TCGA-EJ-A46E-10A-01D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3471f90f-e293-45d1-a6cf-4927be485fd9	757ae720-46cc-4388-a24f-5c8ab52e12f4	g.chr19:10088375G>T	ENST00000264828.3	-	42	3106	c.3021C>A	c.(3019-3021)ggC>ggA	p.G1007G		NM_015719.3	NP_056534.2	P25940	CO5A3_HUMAN	collagen, type V, alpha 3	1007	Triple-helical region.				collagen fibril organization|skin development	collagen type V	collagen binding|extracellular matrix structural constituent			NS(2)|breast(3)|central_nervous_system(2)|endometrium(11)|kidney(23)|large_intestine(12)|liver(2)|lung(35)|ovary(8)|prostate(5)|skin(10)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	116			Epithelial(33;7.11e-05)			CACCAGGGGAGCCCTGAGAAC	0.572000													4	16					0.00909568	0.00909568	1	1	0
FGF16	8823	broad.mit.edu	37	X	76711785	76711785	+	Missense_Mutation	SNP	A	A	T			TCGA-EJ-A46E-01A-31D-A257-08	TCGA-EJ-A46E-10A-01D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3471f90f-e293-45d1-a6cf-4927be485fd9	757ae720-46cc-4388-a24f-5c8ab52e12f4	g.chrX:76711785A>T	ENST00000439435.1	+	2	122	c.122A>T	c.(121-123)aAt>aTt	p.N41I				O43320	FGF16_HUMAN	fibroblast growth factor 16	0					cell-cell signaling|fibroblast growth factor receptor signaling pathway|insulin receptor signaling pathway|metabolic process|organ morphogenesis|response to temperature stimulus	extracellular space	growth factor activity			NS(1)|breast(1)|lung(2)	4						TCACACGTGAATGTGTTTTCC	0.423000													4	70					0	0	1	0	0
LL22NC03-80A10.6	0	broad.mit.edu	37	22	22661478	22661478	+	RNA	SNP	T	T	G			TCGA-EJ-A46E-01A-31D-A257-08	TCGA-EJ-A46E-10A-01D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3471f90f-e293-45d1-a6cf-4927be485fd9	757ae720-46cc-4388-a24f-5c8ab52e12f4	g.chr22:22661478T>G	ENST00000426066.1	+	0	368					NR_027293.1																						CAGATGCGTCTGAAGAAACAT	0.488000													4	77					0	0	1	0	0
CASC5	57082	broad.mit.edu	37	15	40917081	40917081	+	Missense_Mutation	SNP	G	G	A			TCGA-EJ-A46E-01A-31D-A257-08	TCGA-EJ-A46E-10A-01D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3471f90f-e293-45d1-a6cf-4927be485fd9	757ae720-46cc-4388-a24f-5c8ab52e12f4	g.chr15:40917081G>A	ENST00000346991.5	+	11	5087	c.4697G>A	c.(4696-4698)gGa>gAa	p.G1566E	CASC5_ENST00000399668.2_Missense_Mutation_p.G1540E			Q8NG31	CASC5_HUMAN	cancer susceptibility candidate 5	1566					acrosome assembly|attachment of spindle microtubules to kinetochore|cell division|CenH3-containing nucleosome assembly at centromere|mitotic prometaphase|spindle assembly checkpoint	acrosomal vesicle|condensed chromosome kinetochore|cytosol|nucleoplasm	protein binding			NS(1)|breast(7)|central_nervous_system(1)|endometrium(6)|kidney(4)|large_intestine(13)|lung(16)|skin(3)|stomach(4)|upper_aerodigestive_tract(1)|urinary_tract(1)	57		all_cancers(109;2.03e-18)|all_epithelial(112;4.26e-15)|Lung NSC(122;1.12e-10)|all_lung(180;2.59e-09)|Melanoma(134;0.0574)|Ovarian(310;0.0822)|Colorectal(260;0.0946)		GBM - Glioblastoma multiforme(113;4.99e-05)|BRCA - Breast invasive adenocarcinoma(123;0.0861)|COAD - Colon adenocarcinoma(120;0.211)		GTCAATGCTGGAGAAGCACCA	0.343000													4	38					0	0	1	0	0
OR4A5	81318	broad.mit.edu	37	11	51411634	51411634	+	Missense_Mutation	SNP	T	T	C	rs143887524	byFrequency	TCGA-EJ-A46E-01A-31D-A257-08	TCGA-EJ-A46E-10A-01D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3471f90f-e293-45d1-a6cf-4927be485fd9	757ae720-46cc-4388-a24f-5c8ab52e12f4	g.chr11:51411634T>C	ENST00000319760.6	-	1	814	c.762A>G	c.(760-762)atA>atG	p.I254M		NM_001005272.3	NP_001005272.3	Q8NH83	OR4A5_HUMAN	olfactory receptor, family 4, subfamily A, member 5	254					sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			NS(1)|breast(1)|central_nervous_system(1)|endometrium(2)|kidney(1)|large_intestine(8)|lung(28)|ovary(1)|skin(4)|stomach(1)|upper_aerodigestive_tract(1)	49		all_lung(304;0.236)				GTCTAACATATATGAAAATAC	0.388000													4	80					0	0	1	0	0
SRPX2	27286	broad.mit.edu	37	X	99917332	99917332	+	Missense_Mutation	SNP	G	G	A			TCGA-EJ-A46E-01A-31D-A257-08	TCGA-EJ-A46E-10A-01D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3471f90f-e293-45d1-a6cf-4927be485fd9	757ae720-46cc-4388-a24f-5c8ab52e12f4	g.chrX:99917332G>A	ENST00000373004.3	+	4	751	c.323G>A	c.(322-324)aGc>aAc	p.S108N		NM_014467.2	NP_055282.1	O60687	SRPX2_HUMAN	sushi-repeat containing protein, X-linked 2	108	Sushi 1.				angiogenesis|cell motility|cell-cell adhesion|positive regulation of cell migration involved in sprouting angiogenesis|regulation of phosphorylation	cytoplasm|extracellular region	receptor binding			endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(1)|lung(10)|ovary(2)|upper_aerodigestive_tract(1)	19						TGCCTGCCAAGCCGTCGTTGG	0.557000													6	91					0	0	1	0	0
CTC-338M12.9	0	broad.mit.edu	37	5	180708776	180708777	+	RNA	INS	-	-	G	rs140221514		TCGA-EJ-A46E-01A-31D-A257-08	TCGA-EJ-A46E-10A-01D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3471f90f-e293-45d1-a6cf-4927be485fd9	757ae720-46cc-4388-a24f-5c8ab52e12f4	g.chr5:180708776_180708777insG	ENST00000412295.2	+	0	238																											gggcggtaggagggggctggag	0.728													5	4	---	---	---	---					
NUDT11	0	broad.mit.edu	37	X	51239296	51239309	+	Translation_Start_Site	DEL	TCCTCGAGGCAGCC	TCCTCGAGGCAGCC	-	rs78182391		TCGA-EJ-A46E-01A-31D-A257-08	TCGA-EJ-A46E-10A-01D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3471f90f-e293-45d1-a6cf-4927be485fd9	757ae720-46cc-4388-a24f-5c8ab52e12f4	g.chrX:51239296_51239309delTCCTCGAGGCAGCC	ENST00000375992.3	-	0	139_152					NM_018159.3	NP_060629.2	Q96G61	NUD11_HUMAN	nudix (nucleoside diphosphate linked moiety X)-type motif 11							cytoplasm	diphosphoinositol-polyphosphate diphosphatase activity|metal ion binding	p.?(5)		breast(1)|central_nervous_system(1)|endometrium(1)|large_intestine(1)|lung(2)|prostate(1)|upper_aerodigestive_tract(2)	9	Ovarian(276;0.236)					TTGCACTTCATCCTCGAGGCAGCCTCCTCGAGGC	0.692										HNSCC(48;0.14)			6	7	---	---	---	---