Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
MCOLN3	55283	broad.mit.edu	37	1	85486891	85486891	+	Silent	SNP	C	C	T			TCGA-J4-A83L-01A-11D-A34U-08	TCGA-J4-A83L-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe51bd58-bb0e-41cd-aeee-4bf7aa9579a2	fab25240-6b31-4570-b1dc-8e37d42997d0	g.chr1:85486891C>T	ENST00000370589.2	-	12	1441	c.1389G>A	c.(1387-1389)acG>acA	p.T463T	MCOLN3_ENST00000341115.4_Silent_p.T407T|MCOLN3_ENST00000474447.1_5'UTR|WDR63_ENST00000370596.1_Intron	NM_018298.10	NP_060768.8	Q8TDD5	MCLN3_HUMAN	mucolipin 3	463						integral to membrane	ion channel activity			endometrium(6)|kidney(3)|large_intestine(9)|lung(12)|prostate(3)|skin(1)	34				all cancers(265;0.00957)|Epithelial(280;0.0254)		TTTTTGCAAACGTGGCAAACA	0.338000													5	62					0	0	1	0	0
NFIA	4774	broad.mit.edu	37	1	61818241	61818241	+	Splice_Site	SNP	T	T	G			TCGA-J4-A83L-01A-11D-A34U-08	TCGA-J4-A83L-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe51bd58-bb0e-41cd-aeee-4bf7aa9579a2	fab25240-6b31-4570-b1dc-8e37d42997d0	g.chr1:61818241T>G	ENST00000403491.3	+	5	1302		c.e5+2		NFIA_ENST00000371189.4_Splice_Site|NFIA_ENST00000371191.1_Splice_Site|NFIA_ENST00000485903.2_Splice_Site|NFIA_ENST00000479364.1_Splice_Site|NFIA_ENST00000407417.3_Splice_Site|NFIA_ENST00000371185.2_Splice_Site|NFIA_ENST00000371184.2_Intron|NFIA_ENST00000371187.3_Splice_Site	NM_001134673.3|NM_005595.4	NP_001128145.1|NP_005586.1	Q12857	NFIA_HUMAN	nuclear factor I/A						DNA replication|viral genome replication	cell junction|nucleus	DNA binding|sequence-specific DNA binding transcription factor activity|transcription factor binding		NFIA/EHF(2)	endometrium(1)|kidney(2)|large_intestine(8)|lung(20)|pancreas(1)|prostate(1)|skin(1)	34						CTCTACGAGGTAATTTTATTG	0.418000													3	70					0	0	1	0	0
COL12A1	1303	broad.mit.edu	37	6	75887568	75887568	+	Missense_Mutation	SNP	C	C	G			TCGA-J4-A83L-01A-11D-A34U-08	TCGA-J4-A83L-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe51bd58-bb0e-41cd-aeee-4bf7aa9579a2	fab25240-6b31-4570-b1dc-8e37d42997d0	g.chr6:75887568C>G	ENST00000322507.8	-	12	2557	c.2248G>C	c.(2248-2250)Gtt>Ctt	p.V750L	COL12A1_ENST00000416123.2_Missense_Mutation_p.V750L|COL12A1_ENST00000345356.6_Intron|COL12A1_ENST00000483888.2_Missense_Mutation_p.V750L	NM_004370.5	NP_004361.3	Q99715	COCA1_HUMAN	collagen, type XII, alpha 1	750	Fibronectin type-III 4.				cell adhesion|collagen fibril organization|skeletal system development	collagen type XII|extracellular space	extracellular matrix structural constituent conferring tensile strength			breast(7)|central_nervous_system(1)|endometrium(7)|haematopoietic_and_lymphoid_tissue(5)|kidney(5)|large_intestine(44)|liver(1)|lung(77)|ovary(7)|prostate(3)|skin(4)|stomach(2)|upper_aerodigestive_tract(4)|urinary_tract(2)	169						TATCTTAAAACTCTCCCTGGA	0.413000													8	147					0	0	1	0	0
CNTNAP5	129684	broad.mit.edu	37	2	125262060	125262060	+	Silent	SNP	G	G	T			TCGA-J4-A83L-01A-11D-A34U-08	TCGA-J4-A83L-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe51bd58-bb0e-41cd-aeee-4bf7aa9579a2	fab25240-6b31-4570-b1dc-8e37d42997d0	g.chr2:125262060G>T	ENST00000431078.1	+	8	1615	c.1251G>T	c.(1249-1251)ctG>ctT	p.L417L		NM_130773.2	NP_570129.1	Q8WYK1	CNTP5_HUMAN	contactin associated protein-like 5	417	Laminin G-like 2.				cell adhesion|signal transduction	integral to membrane	receptor binding			NS(1)|breast(4)|central_nervous_system(1)|cervix(1)|endometrium(9)|haematopoietic_and_lymphoid_tissue(3)|kidney(4)|large_intestine(24)|lung(100)|ovary(10)|prostate(12)|skin(4)|upper_aerodigestive_tract(3)	176				BRCA - Breast invasive adenocarcinoma(221;0.248)		GAACCCTGCTGCTGAGCCTGG	0.522000													9	57					0.00448238	0.00461045	1	1	0
SERPINE1	5054	broad.mit.edu	37	7	100779051	100779051	+	Silent	SNP	C	C	T			TCGA-J4-A83L-01A-11D-A34U-08	TCGA-J4-A83L-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe51bd58-bb0e-41cd-aeee-4bf7aa9579a2	fab25240-6b31-4570-b1dc-8e37d42997d0	g.chr7:100779051C>T	ENST00000223095.4	+	7	1213	c.1056C>T	c.(1054-1056)aaC>aaT	p.N352N	SERPINE1_ENST00000445463.2_Silent_p.N337N	NM_000602.4	NP_000593.1	P05121	PAI1_HUMAN	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	352					angiogenesis|cellular response to chemical stimulus|cellular response to lipopolysaccharide|chronological cell aging|defense response to Gram-negative bacterium|fibrinolysis|negative regulation of apoptosis|negative regulation of cell adhesion mediated by integrin|negative regulation of fibrinolysis|negative regulation of plasminogen activation|negative regulation of smooth muscle cell migration|negative regulation of smooth muscle cell-matrix adhesion|negative regulation of vascular wound healing|platelet activation|platelet degranulation|positive regulation of angiogenesis|positive regulation of interleukin-8 production|positive regulation of leukotriene production involved in inflammatory response|positive regulation of monocyte chemotaxis|positive regulation of receptor-mediated endocytosis|regulation of receptor activity	extracellular matrix|extracellular space|plasma membrane|platelet alpha granule lumen	protease binding|serine-type endopeptidase inhibitor activity			central_nervous_system(1)|endometrium(5)|kidney(2)|large_intestine(4)|lung(4)|ovary(1)|prostate(3)	20	Lung NSC(181;0.136)|all_lung(186;0.182)				Atorvastatin(DB01076)|Dimethyl sulfoxide(DB01093)|Drotrecogin alfa(DB00055)|Simvastatin(DB00641)|Tenecteplase(DB00031)|Troglitazone(DB00197)|Urokinase(DB00013)	TCGAGGTGAACGAGAGTGGCA	0.582000													5	50					0	0	1	0	0
PAQR6	79957	broad.mit.edu	37	1	156213664	156213664	+	Silent	SNP	C	C	T			TCGA-J4-A83L-01A-11D-A34U-08	TCGA-J4-A83L-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe51bd58-bb0e-41cd-aeee-4bf7aa9579a2	fab25240-6b31-4570-b1dc-8e37d42997d0	g.chr1:156213664C>T	ENST00000335852.1	-	7	1659	c.1044G>A	c.(1042-1044)gcG>gcA	p.A348A	PAQR6_ENST00000368270.1_3'UTR|PAQR6_ENST00000492619.1_5'UTR|PAQR6_ENST00000356983.2_Silent_p.A348A|PAQR6_ENST00000360733.2_Silent_p.A348A|PAQR6_ENST00000292291.5_3'UTR	NM_024897.2	NP_079173.2	Q6TCH4	PAQR6_HUMAN	progestin and adipoQ receptor family member VI	0						integral to membrane	receptor activity			lung(4)|ovary(1)	5	Hepatocellular(266;0.158)					AGCCTGGACACGCATGCATCT	0.582000													12	202					0	0	1	0	0
MTUS2	23281	broad.mit.edu	37	13	29599806	29599806	+	Missense_Mutation	SNP	G	G	A			TCGA-J4-A83L-01A-11D-A34U-08	TCGA-J4-A83L-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe51bd58-bb0e-41cd-aeee-4bf7aa9579a2	fab25240-6b31-4570-b1dc-8e37d42997d0	g.chr13:29599806G>A	ENST00000431530.3	+	1	1059	c.1001G>A	c.(1000-1002)gGa>gAa	p.G334E		NM_001033602.2	NP_001028774.2	Q5JR59	MTUS2_HUMAN	microtubule associated tumor suppressor candidate 2	324						cytoplasm|microtubule	microtubule binding|protein homodimerization activity			NS(1)|endometrium(5)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(6)|lung(3)|prostate(1)|skin(1)	20						GAACAGGAGGGAAAGGCAGCC	0.532000													6	30					0	0	1	0	0
CCDC8	83987	broad.mit.edu	37	19	46914722	46914722	+	Missense_Mutation	SNP	G	G	A			TCGA-J4-A83L-01A-11D-A34U-08	TCGA-J4-A83L-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe51bd58-bb0e-41cd-aeee-4bf7aa9579a2	fab25240-6b31-4570-b1dc-8e37d42997d0	g.chr19:46914722G>A	ENST00000307522.3	-	1	2119	c.1346C>T	c.(1345-1347)cCa>cTa	p.P449L		NM_032040.4	NP_114429.2	Q9H0W5	CCDC8_HUMAN	coiled-coil domain containing 8	449						plasma membrane				breast(1)|central_nervous_system(1)|endometrium(1)|large_intestine(4)|lung(10)|ovary(3)|pancreas(1)|prostate(1)|upper_aerodigestive_tract(1)	23				OV - Ovarian serous cystadenocarcinoma(262;4.66e-05)|all cancers(93;0.000582)|Epithelial(262;0.00428)|GBM - Glioblastoma multiforme(486;0.0421)		CTGGATACCTGGGGCCCCTGC	0.627000													8	29					0	0	1	0	0
SCN1A	6323	broad.mit.edu	37	2	166900411	166900411	+	Missense_Mutation	SNP	C	C	T	rs121918769	byFrequency	TCGA-J4-A83L-01A-11D-A34U-08	TCGA-J4-A83L-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe51bd58-bb0e-41cd-aeee-4bf7aa9579a2	fab25240-6b31-4570-b1dc-8e37d42997d0	g.chr2:166900411C>T	ENST00000423058.2	-	11	1828	c.1811G>A	c.(1810-1812)cGt>cAt	p.R604H	SCN1A_ENST00000375405.3_Missense_Mutation_p.R604H|SCN1A_ENST00000409050.1_Missense_Mutation_p.R604H|SCN1A_ENST00000303395.4_Missense_Mutation_p.R604H|AC010127.3_ENST00000595268.1_RNA|AC010127.3_ENST00000599041.1_RNA|AC010127.3_ENST00000595647.1_RNA	NM_001165963.1|NM_001202435.1	NP_001159435.1|NP_001189364.1	P35498	SCN1A_HUMAN	sodium channel, voltage-gated, type I, alpha subunit	604			R -> H (in SMEI; uncertain pathological significance; dbSNP:rs121918769).			voltage-gated sodium channel complex	voltage-gated sodium channel activity			NS(4)|breast(5)|endometrium(16)|haematopoietic_and_lymphoid_tissue(4)|kidney(8)|large_intestine(33)|lung(87)|ovary(7)|pancreas(1)|prostate(9)|skin(23)|upper_aerodigestive_tract(2)|urinary_tract(1)	200					Lamotrigine(DB00555)|Levetiracetam(DB01202)|Phenacemide(DB01121)|Phenytoin(DB00252)|Topiramate(DB00273)|Zonisamide(DB00909)	GGAATCTCTACGGCTCTCGTT	0.532000													11	51					0	0	1	0	0
MRVI1	10335	broad.mit.edu	37	11	10649268	10649268	+	Missense_Mutation	SNP	C	C	T			TCGA-J4-A83L-01A-11D-A34U-08	TCGA-J4-A83L-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe51bd58-bb0e-41cd-aeee-4bf7aa9579a2	fab25240-6b31-4570-b1dc-8e37d42997d0	g.chr11:10649268C>T	ENST00000547195.1	-	7	972	c.472G>A	c.(472-474)Gag>Aag	p.E158K	MRVI1_ENST00000421747.1_Missense_Mutation_p.E240K|MRVI1_ENST00000552103.1_Missense_Mutation_p.E158K|MRVI1_ENST00000527509.2_Missense_Mutation_p.E158K|MRVI1_ENST00000424001.1_5'UTR|MRVI1_ENST00000423302.2_Missense_Mutation_p.E249K|MRVI1_ENST00000541483.1_Missense_Mutation_p.E249K|MRVI1_ENST00000436272.1_Missense_Mutation_p.E222K|MRVI1_ENST00000558540.1_5'UTR|MRVI1_ENST00000545852.1_5'UTR|MRVI1_ENST00000534266.2_5'UTR|MRVI1_ENST00000531107.1_Missense_Mutation_p.E241K	NM_001100163.2|NM_001206881.1	NP_001093633.1|NP_001193810.1	Q9Y6F6	MRVI1_HUMAN	murine retrovirus integration site 1 homolog	222	Interaction with PRKG1 (By similarity).				platelet activation	endoplasmic reticulum membrane|integral to membrane|perinuclear region of cytoplasm|platelet dense tubular network membrane|sarcoplasmic reticulum				central_nervous_system(2)|cervix(1)|endometrium(4)|kidney(2)|large_intestine(5)|lung(4)|ovary(2)|prostate(2)	22				all cancers(16;2.68e-07)|Epithelial(150;3.04e-07)|BRCA - Breast invasive adenocarcinoma(625;0.0723)		CTCACAGGCTCGCCAGGGTGA	0.557000													16	50					0	0	1	0	0
SIK3	23387	broad.mit.edu	37	11	116827691	116827691	+	Silent	SNP	G	G	A			TCGA-J4-A83L-01A-11D-A34U-08	TCGA-J4-A83L-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe51bd58-bb0e-41cd-aeee-4bf7aa9579a2	fab25240-6b31-4570-b1dc-8e37d42997d0	g.chr11:116827691G>A	ENST00000375300.1	-	2	368	c.363C>T	c.(361-363)tgC>tgT	p.C121C	SIK3_ENST00000434315.2_5'UTR|SIK3_ENST00000292055.4_Silent_p.C63C|SIK3_ENST00000375288.1_5'UTR|SIK3_ENST00000542607.1_Silent_p.C63C|SIK3_ENST00000446921.2_Silent_p.C121C			Q9Y2K2	SIK3_HUMAN	SIK family kinase 3	63	Protein kinase.					cytoplasm	ATP binding|magnesium ion binding|protein binding|protein serine/threonine kinase activity			breast(6)|endometrium(6)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(9)|liver(1)|lung(18)|ovary(4)|pancreas(1)|prostate(2)|skin(3)|stomach(2)|upper_aerodigestive_tract(1)	57						TATGGGGGTGGCAAAGCATCT	0.408000													5	259					0	0	1	0	0
SECISBP2L	9728	broad.mit.edu	37	15	49288768	49288768	+	Missense_Mutation	SNP	A	A	C			TCGA-J4-A83L-01A-11D-A34U-08	TCGA-J4-A83L-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe51bd58-bb0e-41cd-aeee-4bf7aa9579a2	fab25240-6b31-4570-b1dc-8e37d42997d0	g.chr15:49288768A>C	ENST00000559471.1	-	17	2682	c.2419T>G	c.(2419-2421)Tta>Gta	p.L807V	SECISBP2L_ENST00000261847.3_Missense_Mutation_p.L762V	NM_001193489.1	NP_001180418.1	Q93073	SBP2L_HUMAN	SECIS binding protein 2-like	807										breast(1)|endometrium(5)|kidney(8)|large_intestine(12)|lung(11)|pancreas(1)|prostate(4)|skin(2)|stomach(1)|urinary_tract(1)	46						AGTTCTACTAATTTATTAAAC	0.343000													9	118					0	0	1	0	0
UNC5D	137970	broad.mit.edu	37	8	35579908	35579908	+	Missense_Mutation	SNP	G	G	A	rs144081400	byFrequency	TCGA-J4-A83L-01A-11D-A34U-08	TCGA-J4-A83L-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe51bd58-bb0e-41cd-aeee-4bf7aa9579a2	fab25240-6b31-4570-b1dc-8e37d42997d0	g.chr8:35579908G>A	ENST00000453357.2	+	9	1339	c.1283G>A	c.(1282-1284)cGt>cAt	p.R428H	UNC5D_ENST00000416672.1_Missense_Mutation_p.R438H|UNC5D_ENST00000420357.1_Missense_Mutation_p.R366H|UNC5D_ENST00000287272.2_Intron|UNC5D_ENST00000404895.2_Missense_Mutation_p.R433H			Q6UXZ4	UNC5D_HUMAN	unc-5 homolog D (C. elegans)	433					apoptosis|axon guidance	integral to membrane	receptor activity			NS(2)|breast(7)|central_nervous_system(1)|endometrium(8)|haematopoietic_and_lymphoid_tissue(4)|kidney(2)|large_intestine(14)|lung(56)|ovary(3)|pancreas(1)|prostate(2)|skin(4)|upper_aerodigestive_tract(6)|urinary_tract(2)	112				READ - Rectum adenocarcinoma(1;1.31e-05)|Colorectal(1;0.000723)		AAAACAGTCCGTCAAGGTCAG	0.552000													19	80					0	0	1	0	0
TBPL2	387332	broad.mit.edu	37	14	55903530	55903530	+	Silent	SNP	G	G	A			TCGA-J4-A83L-01A-11D-A34U-08	TCGA-J4-A83L-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe51bd58-bb0e-41cd-aeee-4bf7aa9579a2	fab25240-6b31-4570-b1dc-8e37d42997d0	g.chr14:55903530G>A	ENST00000247219.5	-	2	427	c.357C>T	c.(355-357)caC>caT	p.H119H		NM_199047.2	NP_950248.1	Q6SJ96	TBPL2_HUMAN	TATA box binding protein like 2	119					multicellular organismal development|transcription initiation from RNA polymerase II promoter	cytoplasm|nucleus	DNA binding			endometrium(2)|kidney(1)|large_intestine(1)|lung(4)	8						CTTCAGTTTCGTGTTTGCTAA	0.438000													9	44					0	0	1	0	0
WDR48	57599	broad.mit.edu	37	3	39093536	39093536	+	Missense_Mutation	SNP	A	A	G			TCGA-J4-A83L-01A-11D-A34U-08	TCGA-J4-A83L-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe51bd58-bb0e-41cd-aeee-4bf7aa9579a2	fab25240-6b31-4570-b1dc-8e37d42997d0	g.chr3:39093536A>G	ENST00000302313.5	+	1	48	c.20A>G	c.(19-21)cAg>cGg	p.Q7R	WDR48_ENST00000418020.1_5'UTR|WDR48_ENST00000396258.3_5'UTR|WDR48_ENST00000544962.1_Missense_Mutation_p.Q7R	NM_020839.2	NP_065890.1	Q8TAF3	WDR48_HUMAN	WD repeat domain 48	7					interspecies interaction between organisms|protein deubiquitination	lysosome|nucleus	protein binding			breast(2)|kidney(1)|large_intestine(2)|lung(4)|ovary(1)|pancreas(1)|prostate(1)|skin(2)|upper_aerodigestive_tract(1)	15				KIRC - Kidney renal clear cell carcinoma(284;0.0588)|Kidney(284;0.0738)		CATCACCGGCAGAACACAGCA	0.647000													6	17					0	0	1	0	0
USP45	85015	broad.mit.edu	37	6	99936563	99936563	+	Silent	SNP	G	G	C			TCGA-J4-A83L-01A-11D-A34U-08	TCGA-J4-A83L-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe51bd58-bb0e-41cd-aeee-4bf7aa9579a2	fab25240-6b31-4570-b1dc-8e37d42997d0	g.chr6:99936563G>C	ENST00000327681.6	-	6	1144	c.612C>G	c.(610-612)gtC>gtG	p.V204V	USP45_ENST00000500704.2_Silent_p.V204V|USP45_ENST00000329966.5_Silent_p.V204V|USP45_ENST00000392738.2_5'UTR|USP45_ENST00000369233.2_Silent_p.V204V|USP45_ENST00000472914.2_Silent_p.V204V	NM_001080481.1	NP_001073950.1	Q70EL2	UBP45_HUMAN	ubiquitin specific peptidase 45	204					ubiquitin-dependent protein catabolic process		cysteine-type peptidase activity|ubiquitin thiolesterase activity|zinc ion binding			NS(1)|breast(2)|central_nervous_system(1)|endometrium(5)|large_intestine(6)|lung(2)|ovary(1)|skin(1)|stomach(2)|upper_aerodigestive_tract(1)	22		all_cancers(76;0.000208)|Acute lymphoblastic leukemia(125;8.41e-11)|all_hematologic(75;2.56e-07)|all_epithelial(107;0.122)|Colorectal(196;0.133)		BRCA - Breast invasive adenocarcinoma(108;0.0718)		TTACCTGCATGACTGCATTAA	0.318000													4	138					0	0	1	0	0
TNFRSF10D	8793	broad.mit.edu	37	8	23002139	23002139	+	Missense_Mutation	SNP	G	G	A			TCGA-J4-A83L-01A-11D-A34U-08	TCGA-J4-A83L-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe51bd58-bb0e-41cd-aeee-4bf7aa9579a2	fab25240-6b31-4570-b1dc-8e37d42997d0	g.chr8:23002139G>A	ENST00000312584.3	-	7	872	c.778C>T	c.(778-780)Cgg>Tgg	p.R260W		NM_003840.4	NP_003831.2	Q9UBN6	TR10D_HUMAN	tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain	260					anti-apoptosis|apoptosis	integral to membrane	TRAIL binding|transmembrane receptor activity			endometrium(1)|large_intestine(2)|lung(3)|prostate(1)|skin(1)|upper_aerodigestive_tract(1)	9		Prostate(55;0.0421)|Breast(100;0.067)		Colorectal(74;0.0147)|COAD - Colon adenocarcinoma(73;0.0612)		GAACGCCGCCGGAAAAGGACC	0.602000													3	42					0	0	1	0	0
RNF10	9921	broad.mit.edu	37	12	120990388	120990388	+	Silent	SNP	T	T	G			TCGA-J4-A83L-01A-11D-A34U-08	TCGA-J4-A83L-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe51bd58-bb0e-41cd-aeee-4bf7aa9579a2	fab25240-6b31-4570-b1dc-8e37d42997d0	g.chr12:120990388T>G	ENST00000325954.4	+	3	902	c.441T>G	c.(439-441)acT>acG	p.T147T	RNF10_ENST00000413266.2_Silent_p.T147T	NM_014868.4	NP_055683.3	Q8N5U6	RNF10_HUMAN	ring finger protein 10	147	Interaction with MEOX2.				negative regulation of Schwann cell proliferation|positive regulation of myelination|positive regulation of transcription from RNA polymerase II promoter|transcription, DNA-dependent	cytoplasm|nucleus	protein binding|transcription regulatory region DNA binding|zinc ion binding			breast(1)|endometrium(4)|kidney(3)|large_intestine(5)|lung(11)|ovary(2)|upper_aerodigestive_tract(1)	27	all_neural(191;0.0804)|Medulloblastoma(191;0.0922)					TGAATTTCACTTTTGAACCCC	0.498000													5	52					0	0	1	0	0
ETS2	2114	broad.mit.edu	37	21	40190389	40190389	+	Silent	SNP	G	G	A			TCGA-J4-A83L-01A-11D-A34U-08	TCGA-J4-A83L-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe51bd58-bb0e-41cd-aeee-4bf7aa9579a2	fab25240-6b31-4570-b1dc-8e37d42997d0	g.chr21:40190389G>A	ENST00000360214.3	+	8	1090	c.630G>A	c.(628-630)caG>caA	p.Q210Q	ETS2_ENST00000360938.3_Silent_p.Q210Q	NM_001256295.1	NP_001243224.1	P15036	ETS2_HUMAN	v-ets avian erythroblastosis virus E26 oncogene homolog 2	210					positive regulation of transcription, DNA-dependent|skeletal system development	nucleus	protein binding|sequence-specific DNA binding transcription factor activity			NS(1)|breast(2)|endometrium(1)|large_intestine(3)|lung(5)|ovary(1)|pancreas(2)|prostate(1)|skin(1)|upper_aerodigestive_tract(1)	18		Prostate(19;6.33e-08)|all_epithelial(19;0.123)				TGCAGACACAGAATTACCCCA	0.552000													5	132					0	0	1	0	0
NCOR1	9611	broad.mit.edu	37	17	15989710	15989710	+	Silent	SNP	G	G	A			TCGA-J4-A83L-01A-11D-A34U-08	TCGA-J4-A83L-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe51bd58-bb0e-41cd-aeee-4bf7aa9579a2	fab25240-6b31-4570-b1dc-8e37d42997d0	g.chr17:15989710G>A	ENST00000268712.3	-	23	3320	c.3063C>T	c.(3061-3063)ggC>ggT	p.G1021G	NCOR1_ENST00000395851.1_Silent_p.G1037G	NM_006311.3	NP_006302.2	O75376	NCOR1_HUMAN	nuclear receptor corepressor 1	1021	Interaction with ETO.				cellular lipid metabolic process|chromatin modification|negative regulation of JNK cascade|regulation of glycolysis by negative regulation of transcription from an RNA polymerase II promoter|regulation of lipid transport by negative regulation of transcription from an RNA polymerase II promoter|spindle assembly|transcription from RNA polymerase II promoter	nuclear chromatin|spindle microtubule|transcriptional repressor complex	histone deacetylase binding|transcription corepressor activity|transcription regulatory region DNA binding			NS(2)|breast(13)|central_nervous_system(2)|cervix(3)|endometrium(8)|haematopoietic_and_lymphoid_tissue(1)|kidney(9)|large_intestine(17)|lung(26)|ovary(1)|prostate(7)|skin(2)|upper_aerodigestive_tract(6)|urinary_tract(10)	107				UCEC - Uterine corpus endometrioid carcinoma (92;0.101)		GAAGCCGAACGCCTTCAGGGA	0.448000													21	40					0	0	1	0	0
SF3B1	23451	broad.mit.edu	37	2	198267491	198267491	+	Missense_Mutation	SNP	C	C	G			TCGA-J4-A83L-01A-11D-A34U-08	TCGA-J4-A83L-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe51bd58-bb0e-41cd-aeee-4bf7aa9579a2	fab25240-6b31-4570-b1dc-8e37d42997d0	g.chr2:198267491C>G	ENST00000335508.5	-	14	1957	c.1866G>C	c.(1864-1866)gaG>gaC	p.E622D		NM_012433.2	NP_036565.2	O75533	SF3B1_HUMAN	splicing factor 3b, subunit 1, 155kDa	622					nuclear mRNA splicing, via spliceosome	catalytic step 2 spliceosome|nuclear speck|U12-type spliceosomal complex	protein binding	p.E622D(16)		NS(35)|breast(10)|central_nervous_system(3)|endometrium(8)|haematopoietic_and_lymphoid_tissue(524)|kidney(4)|large_intestine(10)|lung(19)|ovary(1)|pancreas(4)|prostate(6)|salivary_gland(1)|skin(4)|testis(1)|upper_aerodigestive_tract(1)|urinary_tract(2)	633			OV - Ovarian serous cystadenocarcinoma(117;0.246)			TACGGACATACTCATCCATGT	0.423000			Mis		myelodysplastic syndrome								6	49					0	0	1	0	0
ZNF322	79692	broad.mit.edu	37	6	26637700	26637700	+	Missense_Mutation	SNP	T	T	A			TCGA-J4-A83L-01A-11D-A34U-08	TCGA-J4-A83L-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe51bd58-bb0e-41cd-aeee-4bf7aa9579a2	fab25240-6b31-4570-b1dc-8e37d42997d0	g.chr6:26637700T>A	ENST00000415922.2	-	4	1727	c.1082A>T	c.(1081-1083)cAc>cTc	p.H361L	ZNF322_ENST00000471278.1_Missense_Mutation_p.H361L	NM_024639.4	NP_078915.2	Q6U7Q0	Z322A_HUMAN	zinc finger protein 322	361					regulation of transcription, DNA-dependent|transcription, DNA-dependent	cytoplasm|nucleus	DNA binding|zinc ion binding										TGAACTCTGGTGGAAGCTTTT	0.428000													8	373					0	0	1	0	0
MYCT1	80177	broad.mit.edu	37	6	153043043	153043043	+	Missense_Mutation	SNP	C	C	A			TCGA-J4-A83L-01A-11D-A34U-08	TCGA-J4-A83L-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe51bd58-bb0e-41cd-aeee-4bf7aa9579a2	fab25240-6b31-4570-b1dc-8e37d42997d0	g.chr6:153043043C>A	ENST00000367245.5	+	2	371	c.363C>A	c.(361-363)aaC>aaA	p.N121K	MYCT1_ENST00000529453.1_Intron	NM_025107.2	NP_079383.2	Q8N699	MYCT1_HUMAN	myc target 1	121						nucleus				NS(1)|breast(1)|endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(3)|lung(7)|ovary(1)|prostate(1)|skin(3)|upper_aerodigestive_tract(1)	20		Ovarian(120;0.0654)		OV - Ovarian serous cystadenocarcinoma(155;1.33e-10)|BRCA - Breast invasive adenocarcinoma(81;0.143)		ACGGCCTCAACAGAACTGGAT	0.517000													4	72					0.014758	0.014758	1	1	0
SNHG14	0	broad.mit.edu	37	15	25468443	25468443	+	RNA	SNP	A	A	G			TCGA-J4-A83L-01A-11D-A34U-08	TCGA-J4-A83L-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe51bd58-bb0e-41cd-aeee-4bf7aa9579a2	fab25240-6b31-4570-b1dc-8e37d42997d0	g.chr15:25468443A>G	ENST00000453082.2	+	0	885				SNORD115-29_ENST00000362834.1_RNA	NR_003343.1																						GATGACTTAAAAATCATGCTC	0.502000													22	413					0	0	1	0	0
ALS2CL	259173	broad.mit.edu	37	3	46723007	46723007	+	Missense_Mutation	SNP	A	A	C			TCGA-J4-A83L-01A-11D-A34U-08	TCGA-J4-A83L-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe51bd58-bb0e-41cd-aeee-4bf7aa9579a2	fab25240-6b31-4570-b1dc-8e37d42997d0	g.chr3:46723007A>C	ENST00000318962.4	-	12	1340	c.1257T>G	c.(1255-1257)tgT>tgG	p.C419W	ALS2CL_ENST00000415953.1_Missense_Mutation_p.C419W	NM_147129.3	NP_667340.2	Q60I27	AL2CL_HUMAN	ALS2 C-terminal like	419					endosome organization|regulation of Rho protein signal transduction		GTPase activator activity|identical protein binding|Rho guanyl-nucleotide exchange factor activity			NS(1)|breast(2)|central_nervous_system(3)|cervix(1)|endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(5)|liver(1)|lung(7)|skin(3)|stomach(2)	29				BRCA - Breast invasive adenocarcinoma(193;0.000726)|KIRC - Kidney renal clear cell carcinoma(197;0.0171)|Kidney(197;0.0202)		TGCCGTAGCCACACATGCTGC	0.602000													8	52					0	0	1	0	0
B3GALT4	8705	broad.mit.edu	37	6	33245516	33245516	+	Missense_Mutation	SNP	C	C	G			TCGA-J4-A83L-01A-11D-A34U-08	TCGA-J4-A83L-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe51bd58-bb0e-41cd-aeee-4bf7aa9579a2	fab25240-6b31-4570-b1dc-8e37d42997d0	g.chr6:33245516C>G	ENST00000451237.1	+	1	600	c.320C>G	c.(319-321)aCg>aGg	p.T107R		NM_003782.3	NP_003773.1	O96024	B3GT4_HUMAN	UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4	107					protein glycosylation	Golgi membrane|integral to membrane	ganglioside galactosyltransferase activity|UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity			breast(2)|endometrium(1)|kidney(1)|large_intestine(1)|lung(1)|ovary(2)|pancreas(1)|prostate(1)|soft_tissue(1)|urinary_tract(2)	13						AGGGTACAGACGCTATTCTTG	0.657000													12	92					0	0	1	0	0
ACO1	48	broad.mit.edu	37	9	32408558	32408558	+	Missense_Mutation	SNP	A	A	G			TCGA-J4-A83L-01A-11D-A34U-08	TCGA-J4-A83L-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe51bd58-bb0e-41cd-aeee-4bf7aa9579a2	fab25240-6b31-4570-b1dc-8e37d42997d0	g.chr9:32408558A>G	ENST00000379923.1	+	5	519	c.313A>G	c.(313-315)Aaa>Gaa	p.K105E	ACO1_ENST00000309951.5_Missense_Mutation_p.K105E|ACO1_ENST00000541043.1_Missense_Mutation_p.K6E	NM_001278352.1	NP_001265281.1	P21399	ACOC_HUMAN	aconitase 1, soluble	105					citrate metabolic process|response to iron(II) ion|tricarboxylic acid cycle	cytosol|endoplasmic reticulum|Golgi apparatus	4 iron, 4 sulfur cluster binding|aconitate hydratase activity|citrate hydro-lyase (cis-aconitate-forming) activity|iron-responsive element binding|isocitrate hydro-lyase (cis-aconitate-forming) activity|metal ion binding|protein binding			breast(1)|endometrium(7)|kidney(5)|large_intestine(6)|lung(6)|ovary(2)|prostate(1)|skin(1)|urinary_tract(1)	30			LUSC - Lung squamous cell carcinoma(29;0.00813)	GBM - Glioblastoma multiforme(74;3.94e-06)		TGATGCTGTGAAAAAGTTAGG	0.428000													12	102					0	0	1	0	0
BMS1	9790	broad.mit.edu	37	10	43315737	43315737	+	Missense_Mutation	SNP	G	G	T			TCGA-J4-A83L-01A-11D-A34U-08	TCGA-J4-A83L-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe51bd58-bb0e-41cd-aeee-4bf7aa9579a2	fab25240-6b31-4570-b1dc-8e37d42997d0	g.chr10:43315737G>T	ENST00000374518.4	+	16	2697	c.2634G>T	c.(2632-2634)gaG>gaT	p.E878D		NM_014753.3	NP_055568.3	Q14692	BMS1_HUMAN	BMS1 ribosome biogenesis factor	878					ribosome assembly	nucleolus	ATP binding|GTP binding|GTPase activity			NS(1)|breast(3)|endometrium(5)|haematopoietic_and_lymphoid_tissue(1)|kidney(6)|large_intestine(15)|lung(23)|ovary(2)|prostate(2)|skin(1)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	62						TTCAGTATGAGGGTTTTCGAC	0.433000													6	99					3.59834e-05	3.81e-05	1	1	0
NLRP10	338322	broad.mit.edu	37	11	7982638	7982638	+	Missense_Mutation	SNP	G	G	A			TCGA-J4-A83L-01A-11D-A34U-08	TCGA-J4-A83L-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe51bd58-bb0e-41cd-aeee-4bf7aa9579a2	fab25240-6b31-4570-b1dc-8e37d42997d0	g.chr11:7982638G>A	ENST00000328600.2	-	2	682	c.521C>T	c.(520-522)tCg>tTg	p.S174L		NM_176821.3	NP_789791.1	Q86W26	NAL10_HUMAN	NLR family, pyrin domain containing 10	174	NACHT.						ATP binding			breast(1)|endometrium(2)|kidney(2)|large_intestine(8)|liver(1)|lung(28)|ovary(2)|pancreas(1)|prostate(2)|skin(8)|upper_aerodigestive_tract(1)|urinary_tract(2)	58				Epithelial(150;1.47e-07)|BRCA - Breast invasive adenocarcinoma(625;0.189)		AGTGCCAGCCGACCCCTGTAG	0.547000													4	41					0	0	1	0	0
CDH10	1008	broad.mit.edu	37	5	24509761	24509761	+	Silent	SNP	C	C	G			TCGA-J4-A83L-01A-11D-A34U-08	TCGA-J4-A83L-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe51bd58-bb0e-41cd-aeee-4bf7aa9579a2	fab25240-6b31-4570-b1dc-8e37d42997d0	g.chr5:24509761C>G	ENST00000264463.4	-	7	1677	c.1170G>C	c.(1168-1170)ctG>ctC	p.L390L		NM_006727.3	NP_006718.2	Q9Y6N8	CAD10_HUMAN	cadherin 10, type 2 (T2-cadherin)	390	Cadherin 4.				adherens junction organization|cell junction assembly|homophilic cell adhesion	integral to membrane|plasma membrane	calcium ion binding	p.L390L(1)		NS(1)|breast(8)|central_nervous_system(2)|cervix(1)|endometrium(9)|kidney(2)|large_intestine(29)|lung(111)|ovary(6)|pancreas(6)|skin(4)|stomach(2)|upper_aerodigestive_tract(4)	185				STAD - Stomach adenocarcinoma(35;0.0556)		GAACTTCAAACAGATAGGAGG	0.398000										HNSCC(23;0.051)			13	51					0	0	1	0	0
MCM10	55388	broad.mit.edu	37	10	13213058	13213058	+	Silent	SNP	C	C	T			TCGA-J4-A83L-01A-11D-A34U-08	TCGA-J4-A83L-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe51bd58-bb0e-41cd-aeee-4bf7aa9579a2	fab25240-6b31-4570-b1dc-8e37d42997d0	g.chr10:13213058C>T	ENST00000378694.1	+	2	219	c.144C>T	c.(142-144)gcC>gcT	p.A48A	MCM10_ENST00000484800.2_Silent_p.A48A|MCM10_ENST00000378714.3_Silent_p.A48A			Q7L590	MCM10_HUMAN	minichromosome maintenance complex component 10	48					cell cycle checkpoint|DNA replication|G1/S transition of mitotic cell cycle|M/G1 transition of mitotic cell cycle	nucleoplasm	metal ion binding|protein binding			central_nervous_system(1)|large_intestine(4)|ovary(2)|skin(1)|stomach(1)	9						TCTTTGATGCCGACGGCGACG	0.458000													19	98					0	0	1	0	0
CANT1	124583	broad.mit.edu	37	17	76993228	76993228	+	Silent	SNP	C	C	T	rs149367726		TCGA-J4-A83L-01A-11D-A34U-08	TCGA-J4-A83L-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe51bd58-bb0e-41cd-aeee-4bf7aa9579a2	fab25240-6b31-4570-b1dc-8e37d42997d0	g.chr17:76993228C>T	ENST00000302345.2	-	2	971	c.477G>A	c.(475-477)gcG>gcA	p.A159A	CANT1_ENST00000392446.5_Silent_p.A159A|CANT1_ENST00000591773.1_Silent_p.A159A	NM_001159773.1|NM_138793.3	NP_001153245.1|NP_620148.1	Q8WVQ1	CANT1_HUMAN	calcium activated nucleotidase 1	159					positive regulation of I-kappaB kinase/NF-kappaB cascade	endoplasmic reticulum membrane|Golgi cisterna membrane|integral to membrane	calcium ion binding|nucleoside-diphosphatase activity|signal transducer activity		CANT1/ETV4(3)	cervix(1)|endometrium(1)|large_intestine(2)|lung(10)|prostate(1)|skin(1)	16			BRCA - Breast invasive adenocarcinoma(99;0.0362)|OV - Ovarian serous cystadenocarcinoma(97;0.139)			TCCCCTTCTCCGCCAGGTGGG	0.567000			T	ETV4	prostate								14	155					0	0	1	0	0
COL11A2	1302	broad.mit.edu	37	6	33159977	33159979	+	In_Frame_Del	DEL	AGG	AGG	-			TCGA-J4-A83L-01A-11D-A34U-08	TCGA-J4-A83L-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe51bd58-bb0e-41cd-aeee-4bf7aa9579a2	fab25240-6b31-4570-b1dc-8e37d42997d0	g.chr6:33159977_33159979delAGG	ENST00000341947.2	-	1	266_268	c.39_41delCCT	c.(37-42)cta>ct	p.LL13del	COL11A2_ENST00000395194.1_In_Frame_Del_p.LL13del|COL11A2_ENST00000395197.1_In_Frame_Del_p.LL13del|COL11A2_ENST00000357486.1_In_Frame_Del_p.LL13del|COL11A2_ENST00000374712.1_In_Frame_Del_p.LL13del|COL11A2_ENST00000374708.4_In_Frame_Del_p.LL13del|COL11A2_ENST00000374713.1_In_Frame_Del_p.LL13del|COL11A2_ENST00000361917.1_In_Frame_Del_p.LL13del|COL11A2_ENST00000374714.1_In_Frame_Del_p.LL13del	NM_080680.2	NP_542411.2	P13942	COBA2_HUMAN	collagen, type XI, alpha 2	13					cartilage development|cell adhesion|collagen fibril organization|sensory perception of sound|soft palate development	collagen type XI	extracellular matrix structural constituent conferring tensile strength|protein binding, bridging			biliary_tract(1)|breast(1)|cervix(2)|endometrium(5)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(13)|liver(1)|lung(27)|ovary(5)|prostate(5)|skin(6)	68						CACCAGAGGTAGGAGGAGGAGGA	0.675													2	4	---	---	---	---					
KMT2C	58508	broad.mit.edu	37	7	151836813	151836813	+	Frame_Shift_Del	DEL	T	T	-			TCGA-J4-A83L-01A-11D-A34U-08	TCGA-J4-A83L-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe51bd58-bb0e-41cd-aeee-4bf7aa9579a2	fab25240-6b31-4570-b1dc-8e37d42997d0	g.chr7:151836813delT	ENST00000355193.2	-	57	14796	c.14578delA	c.(14578-14580)ctfs	p.T4860fs	KMT2C_ENST00000485655.2_Frame_Shift_Del_p.T8fs|KMT2C_ENST00000262189.6_Frame_Shift_Del_p.T4803fs					lysine (K)-specific methyltransferase 2C																		CGAATGATAGTCCCGATGTAC	0.448													9	95	---	---	---	---					
ATAD2	29028	broad.mit.edu	37	8	124368685	124368685	+	Frame_Shift_Del	DEL	A	A	-			TCGA-J4-A83L-01A-11D-A34U-08	TCGA-J4-A83L-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe51bd58-bb0e-41cd-aeee-4bf7aa9579a2	fab25240-6b31-4570-b1dc-8e37d42997d0	g.chr8:124368685delA	ENST00000287394.5	-	13	1697	c.1590delT	c.(1588-1590)ttfs	p.F530fs	ATAD2_ENST00000521903.1_5'UTR	NM_014109.3	NP_054828.2	Q6PL18	ATAD2_HUMAN	ATPase family, AAA domain containing 2	530					regulation of transcription, DNA-dependent|transcription, DNA-dependent	mitochondrion|nucleus	ATP binding|ATPase activity			breast(3)|central_nervous_system(1)|cervix(1)|endometrium(5)|kidney(1)|large_intestine(12)|lung(16)|ovary(3)|prostate(3)|skin(1)|urinary_tract(2)	48	Lung NSC(37;1.25e-09)|Ovarian(258;0.00838)		STAD - Stomach adenocarcinoma(47;0.00288)			CAATTTCGTCAAAAAAAATAA	0.413													7	43	---	---	---	---					
DENND4A	10260	broad.mit.edu	37	15	66030066	66030066	+	Frame_Shift_Del	DEL	G	G	-			TCGA-J4-A83L-01A-11D-A34U-08	TCGA-J4-A83L-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe51bd58-bb0e-41cd-aeee-4bf7aa9579a2	fab25240-6b31-4570-b1dc-8e37d42997d0	g.chr15:66030066delG	ENST00000443035.3	-	7	1234	c.1019delC	c.(1018-1020)ctfs	p.P340fs	DENND4A_ENST00000431932.2_Frame_Shift_Del_p.P340fs	NM_001144823.1	NP_001138295.1	Q7Z401	MYCPP_HUMAN	DENN/MADD domain containing 4A	340	DENN.				regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|protein binding			breast(1)|central_nervous_system(1)|cervix(1)|endometrium(3)|haematopoietic_and_lymphoid_tissue(1)|kidney(7)|large_intestine(17)|lung(11)|ovary(2)|skin(2)|stomach(1)|upper_aerodigestive_tract(2)|urinary_tract(2)	51						AAGGACATGAGGCCCAGAGAT	0.378													2	4	---	---	---	---					
PTPRS	5802	broad.mit.edu	37	19	5223271	5223271	+	Frame_Shift_Del	DEL	G	G	-			TCGA-J4-A83L-01A-11D-A34U-08	TCGA-J4-A83L-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe51bd58-bb0e-41cd-aeee-4bf7aa9579a2	fab25240-6b31-4570-b1dc-8e37d42997d0	g.chr19:5223271delG	ENST00000372412.4	-	18	2768	c.2535delC	c.(2533-2535)ccfs	p.P845fs	PTPRS_ENST00000262963.6_Frame_Shift_Del_p.P840fs|PTPRS_ENST00000588552.1_Intron|PTPRS_ENST00000587303.1_Frame_Shift_Del_p.P844fs|PTPRS_ENST00000348075.2_Frame_Shift_Del_p.P822fs|PTPRS_ENST00000353284.2_Intron|PTPRS_ENST00000588012.1_Frame_Shift_Del_p.P822fs|PTPRS_ENST00000592099.1_Intron|PTPRS_ENST00000357368.4_Frame_Shift_Del_p.P844fs			Q13332	PTPRS_HUMAN	protein tyrosine phosphatase, receptor type, S	844	Fibronectin type-III 6.				cell adhesion	integral to plasma membrane	protein binding|transmembrane receptor protein tyrosine phosphatase activity			NS(1)|biliary_tract(1)|central_nervous_system(1)|endometrium(12)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(12)|liver(1)|lung(9)|ovary(4)|prostate(1)|skin(12)|stomach(2)|upper_aerodigestive_tract(1)	61				UCEC - Uterine corpus endometrioid carcinoma (162;6.64e-05)|BRCA - Breast invasive adenocarcinoma(158;0.0321)|Lung(535;0.182)		GGCTGCCCTCGGGGGTCTGCT	0.726													2	4	---	---	---	---