Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
RP11-146E13.4	0	broad.mit.edu	37	14	19857036	19857036	+	RNA	SNP	A	A	G			TCGA-MG-AAMC-01A-11D-A41K-08	TCGA-MG-AAMC-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	def5beb7-82b8-4e1d-b7ba-6af748d690cb	c0828412-45cb-4358-b5e6-d0e1543d9cf0	g.chr14:19857036A>G	ENST00000548109.1	+	0	72																											CTGGATAATAAAGTTCATCTC	0.373000													3	23					0	0	1	0	0
SDHAP1	0	broad.mit.edu	37	3	195690271	195690271	+	RNA	SNP	T	T	C	rs115852167	by1000genomes	TCGA-MG-AAMC-01A-11D-A41K-08	TCGA-MG-AAMC-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	def5beb7-82b8-4e1d-b7ba-6af748d690cb	c0828412-45cb-4358-b5e6-d0e1543d9cf0	g.chr3:195690271T>C	ENST00000427841.1	-	0	2224					NR_003264.2																						TTGTCGATTATGGGTCTATAT	0.403000													3	21					0	0	1	0	0
RANBP2	5903	broad.mit.edu	37	2	109371498	109371498	+	Silent	SNP	G	G	A			TCGA-MG-AAMC-01A-11D-A41K-08	TCGA-MG-AAMC-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	def5beb7-82b8-4e1d-b7ba-6af748d690cb	c0828412-45cb-4358-b5e6-d0e1543d9cf0	g.chr2:109371498G>A	ENST00000283195.6	+	16	2466	c.2340G>A	c.(2338-2340)ccG>ccA	p.P780P		NM_006267.4	NP_006258.3	P49792	RBP2_HUMAN	RAN binding protein 2	780					carbohydrate metabolic process|glucose transport|mitotic prometaphase|mRNA transport|protein folding|protein import into nucleus|regulation of glucose transport|transmembrane transport|viral reproduction	cytosol|nuclear pore	peptidyl-prolyl cis-trans isomerase activity|Ran GTPase binding|zinc ion binding		RANBP2/ALK(34)	NS(1)|biliary_tract(1)|breast(3)|endometrium(13)|haematopoietic_and_lymphoid_tissue(1)|kidney(21)|large_intestine(19)|lung(51)|pancreas(1)|prostate(8)|skin(7)|upper_aerodigestive_tract(2)|urinary_tract(1)	129						ATTCTACACCGTCTCCTACCA	0.353000													5	342					0	0	1	0	0
CATSPERG	57828	broad.mit.edu	37	19	38858384	38858384	+	Silent	SNP	C	C	T	rs2302184		TCGA-MG-AAMC-01A-11D-A41K-08	TCGA-MG-AAMC-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	def5beb7-82b8-4e1d-b7ba-6af748d690cb	c0828412-45cb-4358-b5e6-d0e1543d9cf0	g.chr19:38858384C>T	ENST00000409235.3	+	25	3013	c.2898C>T	c.(2896-2898)gaC>gaT	p.D966D	CATSPERG_ENST00000410018.1_Silent_p.D926D|CATSPERG_ENST00000215069.4_3'UTR	NM_021185.4	NP_067008.3	Q6ZRH7	CTSRG_HUMAN	catsper channel auxiliary subunit gamma	966					cell differentiation|multicellular organismal development|spermatogenesis	integral to membrane				breast(1)|endometrium(5)|kidney(2)|large_intestine(4)|lung(13)|ovary(1)|pancreas(2)|prostate(6)|skin(3)|stomach(1)|urinary_tract(2)	40						ACAGTGAGGACGAAATCTACC	0.597000													93	158					0	0	1	0	0
TRIOBP	11078	broad.mit.edu	37	22	38122318	38122318	+	Missense_Mutation	SNP	C	C	T			TCGA-MG-AAMC-01A-11D-A41K-08	TCGA-MG-AAMC-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	def5beb7-82b8-4e1d-b7ba-6af748d690cb	c0828412-45cb-4358-b5e6-d0e1543d9cf0	g.chr22:38122318C>T	ENST00000406386.3	+	7	4010	c.3755C>T	c.(3754-3756)tCc>tTc	p.S1252F	RP1-37E16.12_ENST00000455236.1_RNA	NM_001039141.2	NP_001034230.1	Q9H2D6	TARA_HUMAN	TRIO and F-actin binding protein	1252					actin modification|barbed-end actin filament capping	actin cytoskeleton|cytoplasm|nucleus	actin binding|GTP-Rho binding|myosin II binding|protein binding|ubiquitin protein ligase binding			central_nervous_system(1)|endometrium(2)|kidney(1)|large_intestine(1)|lung(3)|ovary(1)|prostate(1)|skin(1)|upper_aerodigestive_tract(1)	12	Melanoma(58;0.0574)					TCTGGGGGCTCCCGGGGCTCA	0.716000													6	47					0	0	1	0	0
AUTS2	26053	broad.mit.edu	37	7	69364311	69364311	+	Missense_Mutation	SNP	C	C	T	rs142957106	byFrequency	TCGA-MG-AAMC-01A-11D-A41K-08	TCGA-MG-AAMC-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	def5beb7-82b8-4e1d-b7ba-6af748d690cb	c0828412-45cb-4358-b5e6-d0e1543d9cf0	g.chr7:69364311C>T	ENST00000342771.4	+	2	670	c.349C>T	c.(349-351)Cgc>Tgc	p.R117C	AUTS2_ENST00000406775.2_Missense_Mutation_p.R117C|AUTS2_ENST00000403018.2_Missense_Mutation_p.R117C	NM_015570.2	NP_056385.1	Q8WXX7	AUTS2_HUMAN	autism susceptibility candidate 2	117								p.R117C(1)		breast(2)|central_nervous_system(2)|endometrium(6)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(12)|lung(14)|ovary(4)|prostate(2)|skin(4)|urinary_tract(1)	50		all_cancers(73;0.0264)|all_epithelial(88;0.0198)|Lung NSC(55;0.0599)|all_lung(88;0.093)		LUSC - Lung squamous cell carcinoma(90;0.082)|Lung(90;0.186)		TGTGGAGAAACGCCAGACGCC	0.488000													27	44					0	0	1	0	0
ANKRD27	84079	broad.mit.edu	37	19	33149850	33149850	+	Silent	SNP	C	C	T			TCGA-MG-AAMC-01A-11D-A41K-08	TCGA-MG-AAMC-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	def5beb7-82b8-4e1d-b7ba-6af748d690cb	c0828412-45cb-4358-b5e6-d0e1543d9cf0	g.chr19:33149850C>T	ENST00000306065.4	-	2	230	c.72G>A	c.(70-72)ttG>ttA	p.L24L	ANKRD27_ENST00000587352.1_Silent_p.L24L|ANKRD27_ENST00000586693.2_5'UTR	NM_032139.2	NP_115515.2	Q96NW4	ANR27_HUMAN	ankyrin repeat domain 27 (VPS9 domain)	24					early endosome to late endosome transport	early endosome|lysosome	GTPase activator activity|guanyl-nucleotide exchange factor activity			breast(3)|endometrium(7)|kidney(2)|large_intestine(6)|lung(15)|ovary(3)|pancreas(1)|prostate(1)|skin(2)|urinary_tract(2)	42	Esophageal squamous(110;0.137)					CTTTGCTGCACAAGTCAGGGC	0.498000													17	19					0	0	1	0	0
TMEM132E	124842	broad.mit.edu	37	17	32959839	32959839	+	Nonsense_Mutation	SNP	G	G	A			TCGA-MG-AAMC-01A-11D-A41K-08	TCGA-MG-AAMC-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	def5beb7-82b8-4e1d-b7ba-6af748d690cb	c0828412-45cb-4358-b5e6-d0e1543d9cf0	g.chr17:32959839G>A	ENST00000321639.5	+	7	1657	c.1329G>A	c.(1327-1329)tgG>tgA	p.W443*		NM_207313.1	NP_997196.1	Q6IEE7	T132E_HUMAN	transmembrane protein 132E	443						integral to membrane				breast(1)|central_nervous_system(2)|cervix(1)|endometrium(6)|haematopoietic_and_lymphoid_tissue(2)|kidney(2)|large_intestine(10)|lung(28)|prostate(1)|skin(2)|upper_aerodigestive_tract(2)	57				BRCA - Breast invasive adenocarcinoma(366;0.231)		TGACAGTCTGGGTCCCCAAGC	0.587000													40	104					0	0	1	0	0
GSK3A	2931	broad.mit.edu	37	19	42738596	42738596	+	Silent	SNP	G	G	A			TCGA-MG-AAMC-01A-11D-A41K-08	TCGA-MG-AAMC-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	def5beb7-82b8-4e1d-b7ba-6af748d690cb	c0828412-45cb-4358-b5e6-d0e1543d9cf0	g.chr19:42738596G>A	ENST00000398249.4	-	5	2280	c.567C>T	c.(565-567)gtC>gtT	p.V189V	GSK3A_ENST00000222330.3_Silent_p.V271V			P49840	GSK3A_HUMAN	glycogen synthase kinase 3 alpha	271	Protein kinase.				insulin receptor signaling pathway|negative regulation of glucose import|negative regulation of insulin receptor signaling pathway|negative regulation of transferase activity|nerve growth factor receptor signaling pathway|phosphatidylinositol-mediated signaling|positive regulation of protein catabolic process	beta-catenin destruction complex|cytosol	ATP binding|protein kinase A catalytic subunit binding|protein serine/threonine kinase activity|tau-protein kinase activity			endometrium(3)|large_intestine(3)|lung(6)|ovary(3)|prostate(2)|skin(1)|urinary_tract(1)	19		Prostate(69;0.00682)				GCTCCCCTCGGACCAACTGCT	0.592000													13	35					0	0	1	0	0
CMYA5	202333	broad.mit.edu	37	5	79028017	79028017	+	Missense_Mutation	SNP	T	T	A			TCGA-MG-AAMC-01A-11D-A41K-08	TCGA-MG-AAMC-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	def5beb7-82b8-4e1d-b7ba-6af748d690cb	c0828412-45cb-4358-b5e6-d0e1543d9cf0	g.chr5:79028017T>A	ENST00000446378.2	+	2	3460	c.3429T>A	c.(3427-3429)agT>agA	p.S1143R		NM_153610.3	NP_705838.3	Q8N3K9	CMYA5_HUMAN	cardiomyopathy associated 5	1143						perinuclear region of cytoplasm				NS(2)|breast(4)|central_nervous_system(1)|cervix(2)|endometrium(7)|haematopoietic_and_lymphoid_tissue(4)|kidney(4)|large_intestine(37)|lung(34)|ovary(6)|pancreas(2)|prostate(5)|skin(5)|stomach(11)|upper_aerodigestive_tract(3)|urinary_tract(1)	128		Lung NSC(167;0.00296)|all_lung(232;0.00327)|Ovarian(174;0.0262)		OV - Ovarian serous cystadenocarcinoma(54;9.85e-46)|Epithelial(54;3.38e-40)|all cancers(79;3.43e-35)		GGGAGGCAAGTTCATCAGTAG	0.423000													5	48					0	0	1	0	0
NELL1	4745	broad.mit.edu	37	11	21555934	21555934	+	Missense_Mutation	SNP	T	T	C			TCGA-MG-AAMC-01A-11D-A41K-08	TCGA-MG-AAMC-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	def5beb7-82b8-4e1d-b7ba-6af748d690cb	c0828412-45cb-4358-b5e6-d0e1543d9cf0	g.chr11:21555934T>C	ENST00000298925.5	+	17	1897	c.1744T>C	c.(1744-1746)Tca>Cca	p.S582P	NELL1_ENST00000529218.1_3'UTR|NELL1_ENST00000532434.1_Intron|NELL1_ENST00000357134.5_Missense_Mutation_p.S554P|NELL1_ENST00000325319.5_Missense_Mutation_p.S497P			Q92832	NELL1_HUMAN	NEL-like 1 (chicken)	554	EGF-like 5; calcium-binding (Potential).				cell adhesion|nervous system development	extracellular region	calcium ion binding|structural molecule activity			NS(1)|breast(3)|endometrium(5)|kidney(3)|large_intestine(15)|lung(36)|ovary(2)|prostate(3)|skin(1)|urinary_tract(1)	70						TGATGAATGTTCAGAGGGAAT	0.458000													43	52					0	0	1	0	0
RPA1	6117	broad.mit.edu	37	17	1795214	1795214	+	Missense_Mutation	SNP	C	C	A			TCGA-MG-AAMC-01A-11D-A41K-08	TCGA-MG-AAMC-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	def5beb7-82b8-4e1d-b7ba-6af748d690cb	c0828412-45cb-4358-b5e6-d0e1543d9cf0	g.chr17:1795214C>A	ENST00000254719.5	+	15	1749	c.1639C>A	c.(1639-1641)Ctt>Att	p.L547I		NM_002945.3	NP_002936.1	P27694	RFA1_HUMAN	replication protein A1, 70kDa	547					cell cycle checkpoint|DNA recombinase assembly|DNA strand elongation involved in DNA replication|G1/S transition of mitotic cell cycle|M/G1 transition of mitotic cell cycle|nucleotide-excision repair, DNA damage removal|nucleotide-excision repair, DNA gap filling|S phase of mitotic cell cycle|telomere maintenance via recombination|telomere maintenance via semi-conservative replication|transcription-coupled nucleotide-excision repair	actin cytoskeleton|cytoplasm|DNA replication factor A complex|PML body	metal ion binding|protein binding|single-stranded DNA binding			breast(1)|endometrium(3)|large_intestine(2)|lung(2)|ovary(2)	10						TGCTGCTTATCTTGGGGAATT	0.343000								Nucleotide excision repair (NER)					24	39					6.12954e-19	7.3159e-19	1	1	0
TBC1D10A	83874	broad.mit.edu	37	22	30691024	30691024	+	Missense_Mutation	SNP	A	A	G			TCGA-MG-AAMC-01A-11D-A41K-08	TCGA-MG-AAMC-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	def5beb7-82b8-4e1d-b7ba-6af748d690cb	c0828412-45cb-4358-b5e6-d0e1543d9cf0	g.chr22:30691024A>G	ENST00000215790.7	-	5	709	c.545T>C	c.(544-546)gTg>gCg	p.V182A	RP1-130H16.18_ENST00000447976.1_Missense_Mutation_p.V56A|TBC1D10A_ENST00000403362.1_Missense_Mutation_p.V94A|TBC1D10A_ENST00000403477.3_Missense_Mutation_p.V189A	NM_031937.2	NP_114143.1	Q9BXI6	TB10A_HUMAN	TBC1 domain family, member 10A	182	Rab-GAP TBC.					intracellular|microvillus	guanyl-nucleotide exchange factor activity|PDZ domain binding|Rab GTPase activator activity			cervix(2)|endometrium(1)|large_intestine(4)|lung(10)|ovary(1)|prostate(1)|skin(1)|upper_aerodigestive_tract(1)|urinary_tract(2)	23						GGCCTTCAGCACACGGAATAG	0.637000													18	26					0	0	1	0	0
MBLAC1	255374	broad.mit.edu	37	7	99725140	99725140	+	Missense_Mutation	SNP	A	A	C			TCGA-MG-AAMC-01A-11D-A41K-08	TCGA-MG-AAMC-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	def5beb7-82b8-4e1d-b7ba-6af748d690cb	c0828412-45cb-4358-b5e6-d0e1543d9cf0	g.chr7:99725140A>C	ENST00000398075.2	+	2	521	c.122A>C	c.(121-123)gAc>gCc	p.D41A		NM_203397.1	NP_981942.1	A4D2B0	MBLC1_HUMAN	metallo-beta-lactamase domain containing 1	41							hydrolase activity|metal ion binding			breast(1)|endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(2)|lung(1)|skin(1)	7						GTGCGCGCCGACGGCTCCGTG	0.746000													4	5					0	0	1	0	0
PTPRN	5798	broad.mit.edu	37	2	220166408	220166408	+	Missense_Mutation	SNP	G	G	A	rs139651840	byFrequency	TCGA-MG-AAMC-01A-11D-A41K-08	TCGA-MG-AAMC-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	def5beb7-82b8-4e1d-b7ba-6af748d690cb	c0828412-45cb-4358-b5e6-d0e1543d9cf0	g.chr2:220166408G>A	ENST00000295718.2	-	7	1268	c.1028C>T	c.(1027-1029)gCg>gTg	p.A343V	PTPRN_ENST00000409251.3_Missense_Mutation_p.A343V|PTPRN_ENST00000423636.2_Missense_Mutation_p.A253V|AC114803.3_ENST00000417355.1_RNA	NM_002846.3	NP_002837.1	Q16849	PTPRN_HUMAN	protein tyrosine phosphatase, receptor type, N	343					response to reactive oxygen species	integral to plasma membrane	transmembrane receptor protein tyrosine phosphatase activity			breast(3)|central_nervous_system(2)|endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(8)|lung(28)|ovary(3)|prostate(4)|skin(11)|upper_aerodigestive_tract(1)|urinary_tract(1)	65		Renal(207;0.0474)		Epithelial(149;4.22e-07)|all cancers(144;8.82e-05)|LUSC - Lung squamous cell carcinoma(224;0.008)|Lung(261;0.00942)|STAD - Stomach adenocarcinoma(1183;0.0875)		CCCATAGCCCGCCAGCACAGC	0.612000													17	36					0	0	1	0	0
SLFN12	55106	broad.mit.edu	37	17	33738370	33738370	+	Missense_Mutation	SNP	C	C	T			TCGA-MG-AAMC-01A-11D-A41K-08	TCGA-MG-AAMC-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	def5beb7-82b8-4e1d-b7ba-6af748d690cb	c0828412-45cb-4358-b5e6-d0e1543d9cf0	g.chr17:33738370C>T	ENST00000394562.1	-	6	2247	c.1724G>A	c.(1723-1725)cGa>cAa	p.R575Q	SLFN12_ENST00000452764.3_Missense_Mutation_p.R575Q|SLFN12_ENST00000304905.5_Missense_Mutation_p.R575Q|SLFN12_ENST00000460530.1_5'UTR			Q8IYM2	SLN12_HUMAN	schlafen family member 12	575							ATP binding			breast(1)|kidney(2)|large_intestine(3)|lung(8)|prostate(1)|skin(1)|stomach(1)|upper_aerodigestive_tract(1)	18		Ovarian(249;0.17)		UCEC - Uterine corpus endometrioid carcinoma (308;0.0182)		GGTGAGCCTTCGACAAGATTT	0.318000													4	87					0	0	1	0	0
SLCO2A1	6578	broad.mit.edu	37	3	133664084	133664084	+	Missense_Mutation	SNP	G	G	T	rs147644142	by1000genomes	TCGA-MG-AAMC-01A-11D-A41K-08	TCGA-MG-AAMC-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	def5beb7-82b8-4e1d-b7ba-6af748d690cb	c0828412-45cb-4358-b5e6-d0e1543d9cf0	g.chr3:133664084G>T	ENST00000310926.4	-	10	1589	c.1316C>A	c.(1315-1317)cCg>cAg	p.P439Q	SLCO2A1_ENST00000493729.1_Missense_Mutation_p.P363Q	NM_005630.2	NP_005621.2	Q92959	SO2A1_HUMAN	solute carrier organic anion transporter family, member 2A1	439	Kazal-like.				sodium-independent organic anion transport	integral to plasma membrane|membrane fraction	prostaglandin transmembrane transporter activity|protein binding			breast(3)|central_nervous_system(1)|cervix(1)|endometrium(3)|large_intestine(5)|lung(10)|ovary(1)|prostate(2)|skin(2)|stomach(2)	30						AGGAGACTGCGGATGTATAGA	0.532000													16	124					6.94344e-10	7.5561e-10	1	1	0
GPR125	166647	broad.mit.edu	37	4	22390725	22390725	+	Silent	SNP	C	C	T			TCGA-MG-AAMC-01A-11D-A41K-08	TCGA-MG-AAMC-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	def5beb7-82b8-4e1d-b7ba-6af748d690cb	c0828412-45cb-4358-b5e6-d0e1543d9cf0	g.chr4:22390725C>T	ENST00000334304.5	-	18	2978	c.2709G>A	c.(2707-2709)cgG>cgA	p.R903R	GPR125_ENST00000282943.5_5'UTR	NM_145290.2	NP_660333.2	Q8IWK6	GP125_HUMAN	G protein-coupled receptor 125	903					neuropeptide signaling pathway	integral to membrane	G-protein coupled receptor activity	p.R903R(1)		breast(1)|endometrium(6)|kidney(2)|large_intestine(10)|lung(33)|pancreas(1)|skin(1)|stomach(1)|urinary_tract(1)	56		Breast(46;0.198)				GTGCGTTTGGCCGACTGCCGT	0.418000													5	185					0	0	1	0	0
AKAP9	10142	broad.mit.edu	37	7	91699396	91699396	+	Missense_Mutation	SNP	T	T	G			TCGA-MG-AAMC-01A-11D-A41K-08	TCGA-MG-AAMC-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	def5beb7-82b8-4e1d-b7ba-6af748d690cb	c0828412-45cb-4358-b5e6-d0e1543d9cf0	g.chr7:91699396T>G	ENST00000359028.2	+	28	6644	c.6419T>G	c.(6418-6420)cTt>cGt	p.L2140R	AKAP9_ENST00000356239.3_Missense_Mutation_p.L2128R|AKAP9_ENST00000358100.2_Missense_Mutation_p.L2140R			Q99996	AKAP9_HUMAN	A kinase (PRKA) anchor protein 9	2140	Glu-rich.				G2/M transition of mitotic cell cycle|signal transduction|synaptic transmission|transport	centrosome|cytosol|Golgi apparatus	receptor binding			NS(1)|autonomic_ganglia(2)|breast(14)|central_nervous_system(3)|cervix(1)|endometrium(13)|kidney(12)|large_intestine(35)|lung(49)|ovary(8)|prostate(6)|skin(8)|stomach(1)|urinary_tract(2)	155	all_cancers(62;2.46e-09)|all_epithelial(64;4.42e-08)|Breast(17;0.00206)|all_lung(186;0.185)|all_hematologic(106;0.215)|Lung NSC(181;0.249)		STAD - Stomach adenocarcinoma(171;6.16e-05)|Lung(22;0.123)|LUSC - Lung squamous cell carcinoma(200;0.225)			TGCAGTGAGCTTTTGCTCTCT	0.348000			T	BRAF	papillary thyroid								42	45					0	0	1	0	0
ATP10B	23120	broad.mit.edu	37	5	160063209	160063209	+	Missense_Mutation	SNP	T	T	A			TCGA-MG-AAMC-01A-11D-A41K-08	TCGA-MG-AAMC-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	def5beb7-82b8-4e1d-b7ba-6af748d690cb	c0828412-45cb-4358-b5e6-d0e1543d9cf0	g.chr5:160063209T>A	ENST00000327245.5	-	11	1954	c.1108A>T	c.(1108-1110)Aca>Tca	p.T370S	CTC-348L5.1_ENST00000523598.1_RNA	NM_025153.2	NP_079429.2	O94823	AT10B_HUMAN	ATPase, class V, type 10B	370					ATP biosynthetic process	integral to membrane	ATP binding|ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism|magnesium ion binding|phospholipid-translocating ATPase activity			NS(2)|autonomic_ganglia(1)|breast(2)|central_nervous_system(2)|endometrium(7)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(5)|liver(2)|lung(37)|ovary(4)|pancreas(1)|prostate(5)|skin(3)|stomach(1)	75	Renal(175;0.00196)	Medulloblastoma(196;0.0377)|all_neural(177;0.121)	Kidney(164;7.83e-05)|KIRC - Kidney renal clear cell carcinoma(164;0.000525)			ATGATCATTGTGAGGAACATG	0.483000													20	29					0	0	1	0	0
VPS11	55823	broad.mit.edu	37	11	118947656	118947656	+	Missense_Mutation	SNP	G	G	T			TCGA-MG-AAMC-01A-11D-A41K-08	TCGA-MG-AAMC-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	def5beb7-82b8-4e1d-b7ba-6af748d690cb	c0828412-45cb-4358-b5e6-d0e1543d9cf0	g.chr11:118947656G>T	ENST00000300793.6	+	9	1327	c.1285G>T	c.(1285-1287)Gcc>Tcc	p.A429S	VPS11_ENST00000527798.1_3'UTR	NM_021729.4	NP_068375.3	Q9H270	VPS11_HUMAN	vacuolar protein sorting 11 homolog (S. cerevisiae)	430					protein transport	endocytic vesicle|HOPS complex|late endosome membrane|lysosomal membrane	nucleotide binding|protein binding|zinc ion binding			autonomic_ganglia(1)|central_nervous_system(1)|cervix(1)|endometrium(4)|kidney(2)|large_intestine(6)|lung(7)|ovary(2)|prostate(1)|skin(2)|urinary_tract(2)	29	all_hematologic(175;0.0839)	Medulloblastoma(222;0.0425)|Breast(348;0.052)|all_neural(223;0.112)		BRCA - Breast invasive adenocarcinoma(274;7.88e-05)		GTTTCTGGATGCCCAGCGCAT	0.537000													4	24					0.00909568	0.00934834	1	1	0
DENND3	22898	broad.mit.edu	37	8	142202641	142202641	+	Missense_Mutation	SNP	C	C	T	rs143494640		TCGA-MG-AAMC-01A-11D-A41K-08	TCGA-MG-AAMC-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	def5beb7-82b8-4e1d-b7ba-6af748d690cb	c0828412-45cb-4358-b5e6-d0e1543d9cf0	g.chr8:142202641C>T	ENST00000519811.1	+	22	3585	c.3515C>T	c.(3514-3516)gCg>gTg	p.A1172V	DENND3_ENST00000523308.1_Missense_Mutation_p.A142V|DENND3_ENST00000262585.2_Missense_Mutation_p.A1092V|DENND3_ENST00000424248.1_Missense_Mutation_p.A1040V			A2RUS2	DEND3_HUMAN	DENN/MADD domain containing 3	1092										breast(2)|endometrium(5)|haematopoietic_and_lymphoid_tissue(1)|kidney(5)|large_intestine(12)|lung(19)|ovary(1)|prostate(3)|skin(4)|stomach(2)|urinary_tract(1)	55	all_cancers(97;7.36e-15)|all_epithelial(106;2.33e-13)|Lung NSC(106;1.23e-05)|all_lung(105;1.75e-05)|Ovarian(258;0.01)|Acute lymphoblastic leukemia(118;0.155)		BRCA - Breast invasive adenocarcinoma(115;0.105)			CAGCTGTGGGCGGCCTGTGCA	0.667000													18	25					0	0	1	0	0
LRRC24	441381	broad.mit.edu	37	8	145749890	145749890	+	Missense_Mutation	SNP	G	G	A			TCGA-MG-AAMC-01A-11D-A41K-08	TCGA-MG-AAMC-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	def5beb7-82b8-4e1d-b7ba-6af748d690cb	c0828412-45cb-4358-b5e6-d0e1543d9cf0	g.chr8:145749890G>A	ENST00000529415.2	-	3	490	c.373C>T	c.(373-375)Cgc>Tgc	p.R125C	LRRC24_ENST00000533758.1_Missense_Mutation_p.R125C|LRRC14_ENST00000292524.1_3'UTR			Q50LG9	LRC24_HUMAN	leucine rich repeat containing 24	125						integral to membrane				breast(2)|endometrium(1)|kidney(1)|lung(1)	5	all_cancers(97;5.56e-11)|all_epithelial(106;3.54e-10)|Lung NSC(106;5.7e-05)|all_lung(105;0.000174)|Ovarian(258;0.0173)|Acute lymphoblastic leukemia(118;0.155)		OV - Ovarian serous cystadenocarcinoma(54;1.48e-41)|Epithelial(56;1.85e-40)|all cancers(56;3.59e-35)|BRCA - Breast invasive adenocarcinoma(115;0.0483)|Colorectal(110;0.055)			TAGAGCACGCGCAGCTGGGCC	0.711000													5	5					0	0	1	0	0
ZNF746	155061	broad.mit.edu	37	7	149191569	149191569	+	Missense_Mutation	SNP	G	G	A			TCGA-MG-AAMC-01A-11D-A41K-08	TCGA-MG-AAMC-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	def5beb7-82b8-4e1d-b7ba-6af748d690cb	c0828412-45cb-4358-b5e6-d0e1543d9cf0	g.chr7:149191569G>A	ENST00000461958.2	-	2	246	c.50C>T	c.(49-51)aCg>aTg	p.T17M	ZNF746_ENST00000340622.3_Missense_Mutation_p.T17M|ZNF746_ENST00000458143.2_Missense_Mutation_p.T17M			Q6NUN9	ZN746_HUMAN	zinc finger protein 746	17					negative regulation of transcription, DNA-dependent|neuron death|regulation of cell death|transcription, DNA-dependent	cytoplasm|nucleus	transcription regulatory region DNA binding|ubiquitin protein ligase binding|zinc ion binding			breast(1)|central_nervous_system(1)|cervix(1)|endometrium(5)|kidney(5)|large_intestine(4)|lung(11)|ovary(3)|prostate(1)|skin(1)|upper_aerodigestive_tract(1)	34	Melanoma(164;0.165)		OV - Ovarian serous cystadenocarcinoma(82;0.00358)			GGCCTGAATCGTGGCTGCCAT	0.532000													14	74					0	0	1	0	0
CD200R1	131450	broad.mit.edu	37	3	112644012	112644012	+	Missense_Mutation	SNP	T	T	A			TCGA-MG-AAMC-01A-11D-A41K-08	TCGA-MG-AAMC-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	def5beb7-82b8-4e1d-b7ba-6af748d690cb	c0828412-45cb-4358-b5e6-d0e1543d9cf0	g.chr3:112644012T>A	ENST00000471858.1	-	5	961	c.729A>T	c.(727-729)ttA>ttT	p.L243F	CD200R1_ENST00000295863.4_Intron|CD200R1_ENST00000308611.3_Missense_Mutation_p.L266F	NM_170780.2	NP_740750.1	Q8TD46	MO2R1_HUMAN	CD200 receptor 1	243					interspecies interaction between organisms|regulation of immune response	extracellular region|integral to membrane|plasma membrane	receptor activity			cervix(1)|endometrium(1)|haematopoietic_and_lymphoid_tissue(2)|kidney(1)|large_intestine(9)|lung(7)|ovary(2)|pancreas(1)|prostate(1)|skin(1)	26						ATGGAATATATAATTTTGCTG	0.299000													15	30					0	0	1	0	0
TRPC4AP	26133	broad.mit.edu	37	20	33665958	33665958	+	Missense_Mutation	SNP	G	G	A			TCGA-MG-AAMC-01A-11D-A41K-08	TCGA-MG-AAMC-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	def5beb7-82b8-4e1d-b7ba-6af748d690cb	c0828412-45cb-4358-b5e6-d0e1543d9cf0	g.chr20:33665958G>A	ENST00000252015.2	-	2	277	c.188C>T	c.(187-189)aCg>aTg	p.T63M	TRPC4AP_ENST00000451813.1_Missense_Mutation_p.T63M|TRPC4AP_ENST00000432634.2_Missense_Mutation_p.T63M			Q8TEL6	TP4AP_HUMAN	transient receptor potential cation channel, subfamily C, member 4 associated protein	63	Interaction with TNFRSF1A (By similarity).				protein ubiquitination|ubiquitin-dependent protein catabolic process	Cul4A-RING ubiquitin ligase complex	protein binding			breast(3)|central_nervous_system(2)|endometrium(3)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(5)|lung(13)|skin(1)|stomach(1)|urinary_tract(1)	32			BRCA - Breast invasive adenocarcinoma(18;0.00936)			GTCCCTCTCCGTCAAAAAAGT	0.443000													24	21					0	0	1	0	0
TMEM173	340061	broad.mit.edu	37	5	138857857	138857857	+	Missense_Mutation	SNP	G	G	A			TCGA-MG-AAMC-01A-11D-A41K-08	TCGA-MG-AAMC-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	def5beb7-82b8-4e1d-b7ba-6af748d690cb	c0828412-45cb-4358-b5e6-d0e1543d9cf0	g.chr5:138857857G>A	ENST00000330794.4	-	6	1090	c.757C>T	c.(757-759)Cgg>Tgg	p.R253W		NM_198282.2	NP_938023.1	Q86WV6	TM173_HUMAN	transmembrane protein 173	253					activation of innate immune response|apoptosis|cellular response to exogenous dsRNA|defense response to virus|innate immune response|interferon-beta production|positive regulation of defense response to virus by host|positive regulation of protein binding|positive regulation of protein import into nucleus, translocation|positive regulation of transcription factor import into nucleus|positive regulation of transcription from RNA polymerase II promoter	endoplasmic reticulum membrane|integral to membrane|mitochondrial outer membrane|perinuclear region of cytoplasm|plasma membrane	protein homodimerization activity|protein kinase binding|transcription factor binding			endometrium(1)|kidney(1)|lung(6)|upper_aerodigestive_tract(1)	9			KIRC - Kidney renal clear cell carcinoma(527;0.00185)|Kidney(363;0.00325)			ACACTTACCCGCTGCCCGTTC	0.577000													39	50					0	0	1	0	0
AGAP11	119385	broad.mit.edu	37	10	88759210	88759210	+	RNA	SNP	C	C	T			TCGA-MG-AAMC-01A-11D-A41K-08	TCGA-MG-AAMC-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	def5beb7-82b8-4e1d-b7ba-6af748d690cb	c0828412-45cb-4358-b5e6-d0e1543d9cf0	g.chr10:88759210C>T	ENST00000444431.1	+	0	340				RP11-96C23.14_ENST00000444180.3_RNA|RP11-96C23.5_ENST00000433214.2_RNA			Q8TF27	AGA11_HUMAN	ankyrin repeat and GTPase domain Arf GTPase activating protein 11						regulation of ARF GTPase activity		ARF GTPase activator activity|zinc ion binding										GTTTAGGTTGCCAAGCTGTTC	0.333000													5	24					0	0	1	0	0
DUOX1	53905	broad.mit.edu	37	15	45453998	45453998	+	Silent	SNP	C	C	A			TCGA-MG-AAMC-01A-11D-A41K-08	TCGA-MG-AAMC-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	def5beb7-82b8-4e1d-b7ba-6af748d690cb	c0828412-45cb-4358-b5e6-d0e1543d9cf0	g.chr15:45453998C>A	ENST00000321429.4	+	31	4326	c.3919C>A	c.(3919-3921)Cgg>Agg	p.R1307R	CTD-2651B20.1_ENST00000558039.1_lincRNA|DUOX1_ENST00000389037.3_Silent_p.R1307R|DUOX1_ENST00000561166.1_Silent_p.R953R	NM_017434.3	NP_059130.2	Q9NRD9	DUOX1_HUMAN	dual oxidase 1	1307	FAD-binding FR-type.				cuticle development|cytokine-mediated signaling pathway|hormone biosynthetic process|hydrogen peroxide biosynthetic process|hydrogen peroxide catabolic process|response to cAMP|superoxide anion generation	apical plasma membrane|integral to membrane	calcium ion binding|electron carrier activity|flavin adenine dinucleotide binding|heme binding|NAD(P)H oxidase activity|NADP binding|peroxidase activity			breast(2)|central_nervous_system(1)|endometrium(5)|kidney(5)|large_intestine(13)|lung(16)|ovary(6)|prostate(1)|skin(3)|stomach(4)|upper_aerodigestive_tract(1)	57		all_cancers(109;5.7e-11)|all_epithelial(112;4.65e-09)|Lung NSC(122;3.55e-06)|all_lung(180;2.56e-05)|Melanoma(134;0.027)		all cancers(107;5.77e-18)|GBM - Glioblastoma multiforme(94;5.11e-07)|COAD - Colon adenocarcinoma(120;0.071)|Colorectal(133;0.0717)		GCAGTGGGTGCGGATCGCTTG	0.647000													19	37					6.44725e-10	7.45464e-10	1	1	0
SETD2	29072	broad.mit.edu	37	3	47125274	47125274	+	Missense_Mutation	SNP	G	G	C			TCGA-MG-AAMC-01A-11D-A41K-08	TCGA-MG-AAMC-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	def5beb7-82b8-4e1d-b7ba-6af748d690cb	c0828412-45cb-4358-b5e6-d0e1543d9cf0	g.chr3:47125274G>C	ENST00000409792.3	-	12	6038	c.5996C>G	c.(5995-5997)cCa>cGa	p.P1999R	SETD2_ENST00000492397.1_5'UTR	NM_014159.6	NP_054878.5	Q9BYW2	SETD2_HUMAN	SET domain containing 2	1999					regulation of transcription, DNA-dependent|transcription, DNA-dependent	chromosome|nucleus	DNA binding|histone-lysine N-methyltransferase activity|oxidoreductase activity|transition metal ion binding			breast(6)|central_nervous_system(5)|endometrium(4)|kidney(63)|large_intestine(18)|lung(26)|ovary(6)|prostate(2)|skin(3)|soft_tissue(1)|stomach(2)|urinary_tract(5)	141		Acute lymphoblastic leukemia(5;0.0169)		BRCA - Breast invasive adenocarcinoma(193;0.000302)|KIRC - Kidney renal clear cell carcinoma(197;0.00732)|Kidney(197;0.00844)		TGTTTTATCTGGCTGTTCTTG	0.413000			"""N, F, S, Mis"""		clear cell renal carcinoma								68	108					0	0	1	0	0
CTBS	1486	broad.mit.edu	37	1	85039999	85040007	+	In_Frame_Del	DEL	GCAGCGCCA	GCAGCGCCA	-	rs3217269		TCGA-MG-AAMC-01A-11D-A41K-08	TCGA-MG-AAMC-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	def5beb7-82b8-4e1d-b7ba-6af748d690cb	c0828412-45cb-4358-b5e6-d0e1543d9cf0	g.chr1:85039999_85040007delGCAGCGCCA	ENST00000370630.4	-	1	140_148	c.92_100delTGGCGCTGC	c.(91-102)cgg>c	p.LALR31del	CTBS_ENST00000477677.1_5'UTR	NM_004388.2	NP_004379.1	Q01459	DIAC_HUMAN	chitobiase, di-N-acetyl-	31						lysosome	cation binding			breast(1)|endometrium(1)|large_intestine(4)|lung(2)|ovary(1)	9				all cancers(265;0.00727)|Epithelial(280;0.0192)|OV - Ovarian serous cystadenocarcinoma(397;0.166)		GCCGCGAGCCgcagcgccagcagcgccag	0.718													2	4	---	---	---	---					
OTOP1	133060	broad.mit.edu	37	4	4228274	4228282	+	In_Frame_Del	DEL	CCACAGCAG	CCACAGCAG	-	rs111245977		TCGA-MG-AAMC-01A-11D-A41K-08	TCGA-MG-AAMC-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	def5beb7-82b8-4e1d-b7ba-6af748d690cb	c0828412-45cb-4358-b5e6-d0e1543d9cf0	g.chr4:4228274_4228282delCCACAGCAG	ENST00000296358.4	-	1	334_342	c.310_318delCTGCTGTGG	c.(310-318)del	p.LLW104del		NM_177998.1	NP_819056.1	Q7RTM1	OTOP1_HUMAN	otopetrin 1	104					biomineral tissue development	extracellular space|integral to membrane		p.L104_W106delLLW(1)		NS(1)|breast(1)|central_nervous_system(2)|endometrium(1)|kidney(2)|large_intestine(3)|liver(4)|lung(14)|ovary(2)|prostate(2)|skin(1)|upper_aerodigestive_tract(1)	34				UCEC - Uterine corpus endometrioid carcinoma (64;0.168)		ACCACAGCATCCACAGCAGCTGCAGCAGC	0.727													7	21	---	---	---	---					
SKIDA1	387640	broad.mit.edu	37	10	21805466	21805467	+	In_Frame_Ins	INS	-	-	CCTCCT	rs138084841	by1000genomes	TCGA-MG-AAMC-01A-11D-A41K-08	TCGA-MG-AAMC-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	def5beb7-82b8-4e1d-b7ba-6af748d690cb	c0828412-45cb-4358-b5e6-d0e1543d9cf0	g.chr10:21805466_21805467insCCTCCT	ENST00000449193.2	-	4	3537_3538	c.1285_1286insAGGAGG	c.(1285-1287)ggg>AGGAGGggg	p.428_429insRR	SKIDA1_ENST00000444772.3_In_Frame_Ins_p.349_350insRR	NM_207371.3	NP_997254.3			SKI/DACH domain containing 1									p.E428_G429insEE(2)									CCCGCTGCccccctcctcctcc	0.619													5	6	---	---	---	---					
TECPR2	9895	broad.mit.edu	37	14	102918941	102918941	+	Frame_Shift_Del	DEL	C	C	-			TCGA-MG-AAMC-01A-11D-A41K-08	TCGA-MG-AAMC-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	def5beb7-82b8-4e1d-b7ba-6af748d690cb	c0828412-45cb-4358-b5e6-d0e1543d9cf0	g.chr14:102918941delC	ENST00000359520.7	+	16	3843	c.3617delC	c.(3616-3618)acfs	p.T1206fs	TECPR2_ENST00000558678.1_Frame_Shift_Del_p.T1206fs	NM_014844.3	NP_055659.2	O15040	TCPR2_HUMAN	tectonin beta-propeller repeat containing 2	1206							protein binding			breast(1)|central_nervous_system(1)|endometrium(6)|kidney(3)|large_intestine(7)|lung(21)|ovary(2)|prostate(3)|skin(4)|stomach(1)|urinary_tract(1)	50						ATGCACTGGACCAGGCTGGAC	0.637													2	4	---	---	---	---					
NPIPB5	100132247	broad.mit.edu	37	16	22545540	22545558	+	Frame_Shift_Del	DEL	CGAGCGTCTGCGGGGGCCG	CGAGCGTCTGCGGGGGCCG	-			TCGA-MG-AAMC-01A-11D-A41K-08	TCGA-MG-AAMC-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	def5beb7-82b8-4e1d-b7ba-6af748d690cb	c0828412-45cb-4358-b5e6-d0e1543d9cf0	g.chr16:22545540_22545558delCGAGCGTCTGCGGGGGCCG	ENST00000424340.1	+	7	1515_1533	c.1236_1254delCGAGCGTCTGCGGGGGCCG	c.(1234-1254)gcfs	p.AERLRGP412fs	NPIPB5_ENST00000415654.1_3'UTR|NPIPB5_ENST00000517539.1_Frame_Shift_Del_p.AERLRGP412fs	NM_001135865.1	NP_001129337.1			nuclear pore complex interacting protein family, member B5																		AGACACCTGCCGAGCGTCTGCGGGGGCCGCTTCCACCCT	0.562													3	6	---	---	---	---					
CDC27	996	broad.mit.edu	37	17	45219612	45219612	+	Frame_Shift_Del	DEL	A	A	-			TCGA-MG-AAMC-01A-11D-A41K-08	TCGA-MG-AAMC-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	def5beb7-82b8-4e1d-b7ba-6af748d690cb	c0828412-45cb-4358-b5e6-d0e1543d9cf0	g.chr17:45219612delA	ENST00000066544.3	-	11	1454	c.1361delT	c.(1360-1362)cafs	p.L454fs	CDC27_ENST00000527547.1_Frame_Shift_Del_p.L454fs|CDC27_ENST00000446365.2_Frame_Shift_Del_p.L393fs|CDC27_ENST00000531206.1_Frame_Shift_Del_p.L460fs	NM_001114091.1|NM_001256.3	NP_001107563.1|NP_001247.3	P30260	CDC27_HUMAN	cell division cycle 27	454					anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process|cell proliferation|mitotic cell cycle spindle assembly checkpoint|mitotic metaphase/anaphase transition|negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle|positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle|protein K11-linked ubiquitination	anaphase-promoting complex|centrosome|cytosol|nucleoplasm|spindle microtubule	protein phosphatase binding			NS(1)|breast(5)|central_nervous_system(3)|cervix(1)|endometrium(2)|kidney(17)|large_intestine(18)|lung(11)|ovary(5)|pancreas(1)|prostate(19)|skin(5)|upper_aerodigestive_tract(2)	90						TGCTTTTTGTAGATTAAAGGC	0.308													8	26	---	---	---	---					
ESF1	51575	broad.mit.edu	37	20	13756820	13756829	+	Frame_Shift_Del	DEL	CTTTCTGAAT	CTTTCTGAAT	-			TCGA-MG-AAMC-01A-11D-A41K-08	TCGA-MG-AAMC-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	def5beb7-82b8-4e1d-b7ba-6af748d690cb	c0828412-45cb-4358-b5e6-d0e1543d9cf0	g.chr20:13756820_13756829delCTTTCTGAAT	ENST00000202816.1	-	3	832_841	c.725_734delATTCAGAAAG	c.(724-735)gcfs	p.DSES242fs		NM_001276380.1|NM_016649.3	NP_001263309.1|NP_057733.2	Q9H501	ESF1_HUMAN	ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)	242					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleolus|nucleoplasm		p.S243S(1)		endometrium(3)|kidney(5)|large_intestine(8)|lung(11)|ovary(2)|skin(1)|stomach(1)	31						TTCACTAACGCTTTCTGAATCTTCCTCCAG	0.390													19	65	---	---	---	---					
BAGE2	85319	broad.mit.edu	37	21	11038813	11038814	+	RNA	INS	-	-	T	rs144107885	by1000genomes	TCGA-MG-AAMC-01A-11D-A41K-08	TCGA-MG-AAMC-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	def5beb7-82b8-4e1d-b7ba-6af748d690cb	c0828412-45cb-4358-b5e6-d0e1543d9cf0	g.chr21:11038813_11038814insT	ENST00000470054.1	-	0	1389_1390									B melanoma antigen family, member 2															Colorectal(6;3.44e-05)|COAD - Colon adenocarcinoma(6;0.00727)|READ - Rectum adenocarcinoma(6;0.0723)	UCEC - Uterine corpus endometrioid carcinoma (6;0.0974)|all cancers(6;2.54e-22)|Epithelial(6;4.21e-19)|OV - Ovarian serous cystadenocarcinoma(6;1.16e-09)|BRCA - Breast invasive adenocarcinoma(6;7.72e-05)|Lung(8;0.000189)|LUSC - Lung squamous cell carcinoma(6;0.00379)|GBM - Glioblastoma multiforme(6;0.00391)|Kidney(17;0.0773)|LUAD - Lung adenocarcinoma(8;0.247)		TGACTGAGATGTAAGTTGTTGG	0.446													7	253	---	---	---	---