Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	default_gene_name	gene_name_source	 ensembl_gene_id	tier	dbSNP	GMAF	n_ref_count	n_alt_count	normal_vaf	t_ref_count	t_alt_count	tumor_vaf	n_ref_count_val	n_alt_count_val	normal_vaf_val	t_ref_count_val	t_alt_count_val	tumor_vaf_val
SYNE2	0	genome.wustl.edu	37	14	64445579	64445579	+	Silent	SNP	C	C	T			TCGA-3B-A9HI-01A-11D-A387-09	TCGA-3B-A9HI-10A-01D-A38A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c7768147-81e0-42bd-aa71-2a835e66dbe4	e6bb0106-9ac8-4f88-b90b-01e3b3269f2f	14	64445579	64445579	C	T	SNP	SYNE2	ENST00000358025	human	ensembl	74_37	+1	known	silent	c.1416	p.N472	0.989	NULL	pfam_CH-domain,pfam_KASH,pfam_Spectrin_repeat,pfam_CAMSAP_CH,superfamily_CH-domain,smart_CH-domain,smart_Spectrin/alpha-actinin,pfscan_CH-domain,pfscan_KASH	-	no_errors	SYNE2	HGNC	ENSG00000054654	tier1	-	-	69	0	0.00	65	28	30.11	41	0	0.00	60	30	33.33
LHX1	0	genome.wustl.edu	37	17	35300104	35300104	+	Silent	SNP	C	C	T			TCGA-3B-A9HI-01A-11D-A387-09	TCGA-3B-A9HI-10A-01D-A38A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c7768147-81e0-42bd-aa71-2a835e66dbe4	e6bb0106-9ac8-4f88-b90b-01e3b3269f2f	17	35300104	35300104	C	T	SNP	LHX1	ENST00000254457	human	ensembl	74_37	+1	known	silent	c.897	p.G299	1.000	NULL	pfam_Znf_LIM,pfam_Homeobox_dom,superfamily_Homeodomain-like,smart_Znf_LIM,smart_Homeobox_dom,pfscan_Znf_LIM,pfscan_Homeobox_dom	-	no_errors	LHX1	HGNC	ENSG00000132130	tier1	-	-	16	0	0.00	28	7	20.00	24	0	0.00	27	6	17.65
REN	0	genome.wustl.edu	37	1	204125025	204125025	+	Missense_Mutation	SNP	C	C	G			TCGA-3B-A9HI-01A-11D-A387-09	TCGA-3B-A9HI-10A-01D-A38A-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c7768147-81e0-42bd-aa71-2a835e66dbe4	e6bb0106-9ac8-4f88-b90b-01e3b3269f2f	1	204125025	204125025	C	G	SNP	REN	ENST00000272190	human	ensembl	74_37	-1	known	missense	c.982	p.G328R	0.228	pfam_Aspartic_peptidase,superfamily_Peptidase_aspartic_dom	pfam_Aspartic_peptidase,pfam_Aspartic_peptidase_N,superfamily_Peptidase_aspartic_dom,prints_Aspartic_peptidase	-	no_errors	REN	HGNC	ENSG00000143839	tier1	-	-	55	0	0.00	41	32	43.84	28	0	0.00	30	42	56.76
HAVCR1	0	genome.wustl.edu	37	5	156482487	156482487	+	Missense_Mutation	SNP	G	G	T			TCGA-3B-A9HI-01A-11D-A387-09	TCGA-3B-A9HI-10A-01D-A38A-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c7768147-81e0-42bd-aa71-2a835e66dbe4	e6bb0106-9ac8-4f88-b90b-01e3b3269f2f	5	156482487	156482487	G	T	SNP	HAVCR1	ENST00000425854	human	ensembl	74_37	-1	known	missense	c.104	p.P35H	0.958	pfam_Ig_V-set,smart_Ig_sub,pfscan_Ig-like_dom	pfam_Ig_V-set,smart_Ig_sub,pfscan_Ig-like_dom	-	no_errors	HAVCR1	HGNC	ENSG00000113249	tier1	-	-	35	0	0.00	65	16	19.75	41	0	0.00	69	9	11.54
MEF2B	0	genome.wustl.edu	37	19	19260125	19260125	+	Silent	SNP	C	C	T			TCGA-3B-A9HI-01A-11D-A387-09	TCGA-3B-A9HI-10A-01D-A38A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c7768147-81e0-42bd-aa71-2a835e66dbe4	e6bb0106-9ac8-4f88-b90b-01e3b3269f2f	19	19260125	19260125	C	T	SNP	MEF2B	ENST00000162023	human	ensembl	74_37	-1	known	silent	c.168	p.Q56	1.000	pfam_TF_MADSbox,superfamily_TF_MADSbox,smart_TF_MADSbox,pfscan_TF_MADSbox,prints_TF_MADSbox	pfam_TF_MADSbox,superfamily_TF_MADSbox,smart_TF_MADSbox,pfscan_TF_MADSbox,prints_TF_MADSbox	-	no_errors	MEF2B	HGNC	ENSG00000213999	tier1	-	-	60	0	0.00	91	16	14.95	23	0	0.00	54	8	12.90
PKLR	0	genome.wustl.edu	37	1	155263113	155263113	+	Missense_Mutation	SNP	C	C	T			TCGA-3B-A9HI-01A-11D-A387-09	TCGA-3B-A9HI-10A-01D-A38A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c7768147-81e0-42bd-aa71-2a835e66dbe4	e6bb0106-9ac8-4f88-b90b-01e3b3269f2f	1	155263113	155263113	C	T	SNP	PKLR	ENST00000342741	human	ensembl	74_37	-1	known	missense	c.1291	p.A431T	0.998	pfam_Pyrv_Knase_brl,superfamily_Pyrv/PenolPyrv_Kinase-like_dom,tigrfam_Pyr_Knase	pfam_Pyrv_Knase_brl,pfam_Pyrv_Knase_C,superfamily_Pyrv/PenolPyrv_Kinase-like_dom,superfamily_Pyrv_Knase_C,superfamily_Pyrv_Knase-like_insert_dom,prints_Pyr_Knase,tigrfam_Pyr_Knase	-	no_errors	PKLR	HGNC	ENSG00000143627	tier1	-	-	65	0	0.00	114	11	8.80	24	0	0.00	84	21	20.00
ZNF852	0	genome.wustl.edu	37	3	44541497	44541497	+	Missense_Mutation	SNP	G	G	A			TCGA-3B-A9HI-01A-11D-A387-09	TCGA-3B-A9HI-10A-01D-A38A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c7768147-81e0-42bd-aa71-2a835e66dbe4	e6bb0106-9ac8-4f88-b90b-01e3b3269f2f	3	44541497	44541497	G	A	SNP	ZNF852	ENST00000436261	human	ensembl	74_37	-1	known	missense	c.772	p.L258F	0.007	smart_Znf_C2H2-like,pfscan_Znf_C2H2	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF852	HGNC	ENSG00000178917	tier1	-	-	55	0	0.00	49	22	30.56	15	0	0.00	39	8	17.02
CHAF1A	0	genome.wustl.edu	37	19	4430604	4430604	+	Missense_Mutation	SNP	A	A	G			TCGA-3B-A9HI-01A-11D-A387-09	TCGA-3B-A9HI-10A-01D-A38A-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c7768147-81e0-42bd-aa71-2a835e66dbe4	e6bb0106-9ac8-4f88-b90b-01e3b3269f2f	19	4430604	4430604	A	G	SNP	CHAF1A	ENST00000301280	human	ensembl	74_37	+1	known	missense	c.1913	p.H638R	1.000	NULL	pfam_CAF1A	-	no_errors	CHAF1A	HGNC	ENSG00000167670	tier1	-	-	55	0	0.00	64	18	21.95	98	0	0.00	91	37	28.91
TUBGCP3	0	genome.wustl.edu	37	13	113153364	113153364	+	Missense_Mutation	SNP	T	T	A			TCGA-3B-A9HI-01A-11D-A387-09	TCGA-3B-A9HI-10A-01D-A38A-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c7768147-81e0-42bd-aa71-2a835e66dbe4	e6bb0106-9ac8-4f88-b90b-01e3b3269f2f	13	113153364	113153364	T	A	SNP	TUBGCP3	ENST00000261965	human	ensembl	74_37	-1	known	missense	c.2443	p.I815F	0.001	NULL	pfam_TUBGCP	-	no_errors	TUBGCP3	HGNC	ENSG00000126216	tier1	-	-	47	0	0.00	87	26	23.01	56	0	0.00	138	36	20.69
COL18A1	0	genome.wustl.edu	37	21	46925093	46925093	+	Missense_Mutation	SNP	C	C	A			TCGA-3B-A9HI-01A-11D-A387-09	TCGA-3B-A9HI-10A-01D-A38A-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c7768147-81e0-42bd-aa71-2a835e66dbe4	e6bb0106-9ac8-4f88-b90b-01e3b3269f2f	21	46925093	46925093	C	A	SNP	COL18A1	ENST00000359759	human	ensembl	74_37	+1	known	missense	c.4159	p.P1387T	1.000	NULL	pfam_Collagenase_NC10/endostatin,pfam_DUF959_COL18_N,pfam_Collagen,pfam_Frizzled_dom,superfamily_C-type_lectin_fold,superfamily_ConA-like_lec_gl_sf,superfamily_Frizzled_dom,smart_Frizzled_dom,smart_Laminin_G,pfscan_Frizzled_dom	-	no_errors	COL18A1	HGNC	ENSG00000182871	tier1	-	-	70	0	0.00	83	15	15.31	17	0	0.00	23	4	14.81
XIRP2	0	genome.wustl.edu	37	2	168104932	168104932	+	Missense_Mutation	SNP	C	C	T			TCGA-3B-A9HI-01A-11D-A387-09	TCGA-3B-A9HI-10A-01D-A38A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c7768147-81e0-42bd-aa71-2a835e66dbe4	e6bb0106-9ac8-4f88-b90b-01e3b3269f2f	2	168104932	168104932	C	T	SNP	XIRP2	ENST00000295237	human	ensembl	74_37	+1	known	missense	c.7030	p.L2344F	0.921	NULL	pfam_Actin-binding_Xin_repeat	-	no_errors	XIRP2	HGNC	ENSG00000163092	tier1	-	-	53	0	0.00	56	15	21.13	53	0	0.00	58	12	17.14
FBXO3	0	genome.wustl.edu	37	11	33773135	33773135	+	Nonsense_Mutation	SNP	C	C	T			TCGA-3B-A9HI-01A-11D-A387-09	TCGA-3B-A9HI-10A-01D-A38A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c7768147-81e0-42bd-aa71-2a835e66dbe4	e6bb0106-9ac8-4f88-b90b-01e3b3269f2f	11	33773135	33773135	C	T	SNP	FBXO3	ENST00000265651	human	ensembl	74_37	-1	known	nonsense	c.743	p.W248*	1.000	smart_SMI1/KNR4_like_dom	pfam_ApaG_domain,pfam_F-box_dom,superfamily_ApaG_domain,superfamily_F-box_dom,smart_F-box_dom,smart_SMI1/KNR4_like_dom,pfscan_ApaG_domain,pfscan_F-box_dom	-	no_errors	FBXO3	HGNC	ENSG00000110429	tier1	-	-	51	0	0.00	82	11	11.83	55	0	0.00	81	18	18.18
DYM	0	genome.wustl.edu	37	18	46860165	46860165	+	Missense_Mutation	SNP	A	A	C			TCGA-3B-A9HI-01A-11D-A387-09	TCGA-3B-A9HI-10A-01D-A38A-09	A	A	A	C	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c7768147-81e0-42bd-aa71-2a835e66dbe4	e6bb0106-9ac8-4f88-b90b-01e3b3269f2f	18	46860165	46860165	A	C	SNP	DYM	ENST00000269445	human	ensembl	74_37	-1	known	missense	c.553	p.C185G	1.000	pfam_Dymeclin	pfam_Dymeclin,superfamily_ARM-type_fold	-	no_errors	DYM	HGNC	ENSG00000141627	tier1	-	-	31	0	0.00	34	21	38.18	52	0	0.00	66	33	33.00
LAPTM5	0	genome.wustl.edu	37	1	31210526	31210526	+	Silent	SNP	C	C	T			TCGA-3B-A9HI-01A-11D-A387-09	TCGA-3B-A9HI-10A-01D-A38A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c7768147-81e0-42bd-aa71-2a835e66dbe4	e6bb0106-9ac8-4f88-b90b-01e3b3269f2f	1	31210526	31210526	C	T	SNP	LAPTM5	ENST00000294507	human	ensembl	74_37	-1	known	silent	c.531	p.E177	0.283	pfam_LAPTM4/5,tigrfam_LAPTM_4A/5	pfam_LAPTM4/5,tigrfam_LAPTM_4A/5	-	no_errors	LAPTM5	HGNC	ENSG00000162511	tier1	-	-	45	0	0.00	52	14	21.21	47	0	0.00	76	10	11.63
SCAMP5	0	genome.wustl.edu	37	15	75305127	75305127	+	Missense_Mutation	SNP	C	C	T			TCGA-3B-A9HI-01A-11D-A387-09	TCGA-3B-A9HI-10A-01D-A38A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c7768147-81e0-42bd-aa71-2a835e66dbe4	e6bb0106-9ac8-4f88-b90b-01e3b3269f2f	15	75305127	75305127	C	T	SNP	SCAMP5	ENST00000545456	human	ensembl	74_37	+1	known	missense	c.61	p.P21S	0.998	NULL	pfam_SCAMP	-	no_errors	SCAMP5	HGNC	ENSG00000198794	tier1	-	-	33	0	0.00	62	18	22.50	43	0	0.00	87	15	14.71
SLC17A6	0	genome.wustl.edu	37	11	22391670	22391670	+	Missense_Mutation	SNP	T	T	C			TCGA-3B-A9HI-01A-11D-A387-09	TCGA-3B-A9HI-10A-01D-A38A-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c7768147-81e0-42bd-aa71-2a835e66dbe4	e6bb0106-9ac8-4f88-b90b-01e3b3269f2f	11	22391670	22391670	T	C	SNP	SLC17A6	ENST00000263160	human	ensembl	74_37	+1	known	missense	c.977	p.F326S	1.000	pfam_MFS,superfamily_MFS_dom_general_subst_transpt,pfscan_MFS_dom	pfam_MFS,superfamily_MFS_dom_general_subst_transpt,pfscan_MFS_dom	-	no_errors	SLC17A6	HGNC	ENSG00000091664	tier1	-	-	77	0	0.00	95	23	19.49	35	0	0.00	72	13	15.29
PCDHA6	0	genome.wustl.edu	37	5	140209098	140209098	+	Silent	SNP	C	C	T			TCGA-3B-A9HI-01A-11D-A387-09	TCGA-3B-A9HI-10A-01D-A38A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c7768147-81e0-42bd-aa71-2a835e66dbe4	e6bb0106-9ac8-4f88-b90b-01e3b3269f2f	5	140209098	140209098	C	T	SNP	PCDHA6	ENST00000529310	human	ensembl	74_37	+1	known	silent	c.1422	p.I474	0.998	pfam_Cadherin,superfamily_Cadherin-like,pfscan_Cadherin	pfam_Cadherin,pfam_Cadherin_N,superfamily_Cadherin-like,smart_Cadherin,prints_Cadherin,pfscan_Cadherin	-	no_errors	PCDHA6	HGNC	ENSG00000081842	tier1	rs146722468	-	284	0	0.00	261	66	20.18	28	0	0.00	13	3	18.75
ADAM21	0	genome.wustl.edu	37	14	70924558	70924558	+	Nonsense_Mutation	SNP	C	C	G			TCGA-3B-A9HI-01A-11D-A387-09	TCGA-3B-A9HI-10A-01D-A38A-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c7768147-81e0-42bd-aa71-2a835e66dbe4	e6bb0106-9ac8-4f88-b90b-01e3b3269f2f	14	70924558	70924558	C	G	SNP	ADAM21	ENST00000267499	human	ensembl	74_37	+1	known	nonsense	c.342	p.Y114*	0.288	pfam_Peptidase_M12B_N	pfam_Peptidase_M12B,pfam_ADAM_Cys-rich,pfam_Peptidase_M12B_N,pfam_Blood-coag_inhib_Disintegrin,superfamily_Blood-coag_inhib_Disintegrin,smart_Blood-coag_inhib_Disintegrin,smart_ADAM_Cys-rich,pfscan_Blood-coag_inhib_Disintegrin,pfscan_Peptidase_M12B,prints_Blood-coag_inhib_Disintegrin	-	no_errors	ADAM21	HGNC	ENSG00000139985	tier1	-	-	36	0	0.00	60	9	13.04	71	0	0.00	119	26	17.93
OR56A3	0	genome.wustl.edu	37	11	5969021	5969021	+	Missense_Mutation	SNP	G	G	A			TCGA-3B-A9HI-01A-11D-A387-09	TCGA-3B-A9HI-10A-01D-A38A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c7768147-81e0-42bd-aa71-2a835e66dbe4	e6bb0106-9ac8-4f88-b90b-01e3b3269f2f	11	5969021	5969021	G	A	SNP	OR56A3	ENST00000329564	human	ensembl	74_37	+1	known	missense	c.445	p.A149T	0.000	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR56A3	HGNC	ENSG00000184478	tier1	-	-	39	0	0.00	43	11	20.37	89	0	0.00	105	19	15.32
COL28A1	0	genome.wustl.edu	37	7	7571327	7571327	+	Missense_Mutation	SNP	C	C	G			TCGA-3B-A9HI-01A-11D-A387-09	TCGA-3B-A9HI-10A-01D-A38A-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c7768147-81e0-42bd-aa71-2a835e66dbe4	e6bb0106-9ac8-4f88-b90b-01e3b3269f2f	7	7571327	7571327	C	G	SNP	COL28A1	ENST00000399429	human	ensembl	74_37	-1	known	missense	c.333	p.W111C	1.000	pfam_VWF_A,smart_VWF_A,pfscan_VWF_A	pfam_Collagen,pfam_VWF_A,pfam_Prot_inh_Kunz-m,superfamily_Prot_inh_Kunz-m,smart_VWF_A,smart_Prot_inh_Kunz-m,pfscan_VWF_A,pfscan_Prot_inh_Kunz-m	-	no_errors	COL28A1	HGNC	ENSG00000215018	tier1	-	-	23	0	0.00	43	11	20.37	53	0	0.00	118	25	17.36
CCDC146	0	genome.wustl.edu	37	7	76912006	76912006	+	Missense_Mutation	SNP	G	G	A			TCGA-3B-A9HI-01A-11D-A387-09	TCGA-3B-A9HI-10A-01D-A38A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c7768147-81e0-42bd-aa71-2a835e66dbe4	e6bb0106-9ac8-4f88-b90b-01e3b3269f2f	7	76912006	76912006	G	A	SNP	CCDC146	ENST00000285871	human	ensembl	74_37	+1	known	missense	c.2052	p.M684I	1.000	NULL	NULL	-	no_errors	CCDC146	HGNC	ENSG00000135205	tier1	-	-	54	0	0.00	85	13	13.27	34	0	0.00	70	18	20.22
ZNF467	0	genome.wustl.edu	37	7	149461979	149461979	+	Missense_Mutation	SNP	T	T	C			TCGA-3B-A9HI-01A-11D-A387-09	TCGA-3B-A9HI-10A-01D-A38A-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c7768147-81e0-42bd-aa71-2a835e66dbe4	e6bb0106-9ac8-4f88-b90b-01e3b3269f2f	7	149461979	149461979	T	C	SNP	ZNF467	ENST00000302017	human	ensembl	74_37	-1	known	missense	c.1612	p.T538A	1.000	pfscan_Znf_C2H2	pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2	-	no_errors	ZNF467	HGNC	ENSG00000181444	tier1	-	-	132	0	0.00	178	30	14.42	28	0	0.00	21	3	12.50
KPNB1	0	genome.wustl.edu	37	17	45735974	45735974	+	Missense_Mutation	SNP	C	C	T			TCGA-3B-A9HI-01A-11D-A387-09	TCGA-3B-A9HI-10A-01D-A38A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c7768147-81e0-42bd-aa71-2a835e66dbe4	e6bb0106-9ac8-4f88-b90b-01e3b3269f2f	17	45735974	45735974	C	T	SNP	KPNB1	ENST00000290158	human	ensembl	74_37	+1	known	missense	c.584	p.T195M	1.000	superfamily_ARM-type_fold	pfam_HEAT,pfam_Importin-beta_N,pfam_Armadillo,superfamily_ARM-type_fold,smart_Importin-beta_N,smart_Armadillo,pfscan_HEAT_type_2,pfscan_Importin-beta_N	-	no_errors	KPNB1	HGNC	ENSG00000108424	tier1	-	-	35	0	0.00	31	11	26.19	58	0	0.00	55	11	16.67
HERC2P3	0	genome.wustl.edu	37	15	20588706	20588706	+	R	SNP	T	T	C			TCGA-3B-A9HI-01A-11D-A387-09	TCGA-3B-A9HI-10A-01D-A38A-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c7768147-81e0-42bd-aa71-2a835e66dbe4	e6bb0106-9ac8-4f88-b90b-01e3b3269f2f	15	20588706	20588706	T	C	SNP	HERC2P3	ENST00000426501	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.002	-	-	-	no_errors	HERC2P3	HGNC	ENSG00000180229	tier1	-	-	76	0	0.00	78	22	21.78	15	0	0.00	29	6	17.14
POLD1	0	genome.wustl.edu	37	19	50912435	50912435	+	Missense_Mutation	SNP	C	C	T			TCGA-3B-A9HI-01A-11D-A387-09	TCGA-3B-A9HI-10A-01D-A38A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c7768147-81e0-42bd-aa71-2a835e66dbe4	e6bb0106-9ac8-4f88-b90b-01e3b3269f2f	19	50912435	50912435	C	T	SNP	POLD1	ENST00000440232	human	ensembl	74_37	+1	known	missense	c.1949	p.S650L	0.089	pfam_D-dir_D_pol_B_multi_dom,smart_D-dir_D_pol_B,tigrfam_D-dir_D_pol_B_pol2	pfam_D-dir_D_pol_B_multi_dom,pfam_D-dir_D_pol_B_exonuc,superfamily_RNaseH-like_dom,smart_D-dir_D_pol_B,prints_D-dir_D_pol_B,tigrfam_D-dir_D_pol_B_pol2	-	no_errors	POLD1	HGNC	ENSG00000062822	tier1	-	-	30	0	0.00	49	20	28.99	52	0	0.00	77	29	27.36
SLC9A3	0	genome.wustl.edu	37	5	482667	482667	+	Missense_Mutation	SNP	A	A	T			TCGA-3B-A9HI-01A-11D-A387-09	TCGA-3B-A9HI-10A-01D-A38A-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c7768147-81e0-42bd-aa71-2a835e66dbe4	e6bb0106-9ac8-4f88-b90b-01e3b3269f2f	5	482667	482667	A	T	SNP	SLC9A3	ENST00000264938	human	ensembl	74_37	-1	known	missense	c.1352	p.F451Y	0.992	pfam_Cation/H_exchanger,tigrfam_NaH_exchanger	pfam_Cation/H_exchanger,superfamily_Reg_factor_effector_dom,prints_Na/H_exchanger_3/5,prints_NaH_exchanger,tigrfam_NaH_exchanger	-	no_errors	SLC9A3	HGNC	ENSG00000066230	tier1	-	-	124	0	0.00	163	17	9.39	71	0	0.00	73	10	12.05
IGFALS	0	genome.wustl.edu	37	16	1840734	1840734	+	Missense_Mutation	SNP	A	A	G			TCGA-3B-A9HI-01A-11D-A387-09	TCGA-3B-A9HI-10A-01D-A38A-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c7768147-81e0-42bd-aa71-2a835e66dbe4	e6bb0106-9ac8-4f88-b90b-01e3b3269f2f	16	1840734	1840734	A	G	SNP	IGFALS	ENST00000415638	human	ensembl	74_37	-1	known	missense	c.1799	p.V600A	0.810	smart_Cys-rich_flank_reg_C	pfam_Leu-rich_rpt,pfam_LRR-contain_N,smart_LRR-contain_N,smart_Leu-rich_rpt_typical-subtyp,smart_Cys-rich_flank_reg_C	-	no_errors	IGFALS	HGNC	ENSG00000099769	tier1	-	-	242	0	0.00	241	108	30.95	36	0	0.00	44	18	28.57
ERGIC1	0	genome.wustl.edu	37	5	172362219	172362219	+	Missense_Mutation	SNP	G	G	A			TCGA-3B-A9HI-01A-11D-A387-09	TCGA-3B-A9HI-10A-01D-A38A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c7768147-81e0-42bd-aa71-2a835e66dbe4	e6bb0106-9ac8-4f88-b90b-01e3b3269f2f	5	172362219	172362219	G	A	SNP	ERGIC1	ENST00000393784	human	ensembl	74_37	+1	known	missense	c.671	p.R224H	1.000	pfam_Erv_C	pfam_Erv_C	-	no_errors	ERGIC1	HGNC	ENSG00000113719	tier1	-	-	78	0	0.00	161	30	15.62	30	0	0.00	64	10	13.51
RARB	0	genome.wustl.edu	37	3	25502747	25502747	+	Missense_Mutation	SNP	C	C	G			TCGA-3B-A9HI-01A-11D-A387-09	TCGA-3B-A9HI-10A-01D-A38A-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c7768147-81e0-42bd-aa71-2a835e66dbe4	e6bb0106-9ac8-4f88-b90b-01e3b3269f2f	3	25502747	25502747	C	G	SNP	RARB	ENST00000404969	human	ensembl	74_37	+1	known	missense	c.242	p.P81R	1.000	NULL	pfam_Znf_hrmn_rcpt,pfam_Nucl_hrmn_rcpt_lig-bd_core,superfamily_Nucl_hormone_rcpt_ligand-bd,smart_Znf_hrmn_rcpt,smart_Nucl_hrmn_rcpt_lig-bd_core,pfscan_Znf_hrmn_rcpt,prints_Retinoic_acid_rcpt,prints_Str_hrmn_rcpt,prints_Znf_hrmn_rcpt,prints_Nuc_orph_rcpt,prints_Retinoid-X_rcpt/HNF4	-	no_errors	RARB	HGNC	ENSG00000077092	tier1	-	-	44	0	0.00	75	15	16.67	48	0	0.00	135	23	14.56
POM121L12	0	genome.wustl.edu	37	7	53103958	53103958	+	Silent	SNP	C	C	T			TCGA-3B-A9HI-01A-11D-A387-09	TCGA-3B-A9HI-10A-01D-A38A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c7768147-81e0-42bd-aa71-2a835e66dbe4	e6bb0106-9ac8-4f88-b90b-01e3b3269f2f	7	53103958	53103958	C	T	SNP	POM121L12	ENST00000408890	human	ensembl	74_37	+1	known	silent	c.594	p.F198	0.001	NULL	NULL	-	no_errors	POM121L12	HGNC	ENSG00000221900	tier1	-	-	80	0	0.00	199	31	13.42	46	0	0.00	40	16	28.57
ZNF99	0	genome.wustl.edu	37	19	22942170	22942170	+	Missense_Mutation	SNP	A	A	T			TCGA-3B-A9HI-01A-11D-A387-09	TCGA-3B-A9HI-10A-01D-A38A-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c7768147-81e0-42bd-aa71-2a835e66dbe4	e6bb0106-9ac8-4f88-b90b-01e3b3269f2f	19	22942170	22942170	A	T	SNP	ZNF99	ENST00000596209	human	ensembl	74_37	-1	novel	missense	c.541	p.S181T	0.002	smart_Znf_C2H2-like,pfscan_Znf_C2H2	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF99	HGNC	ENSG00000213973	tier1	-	-	72	0	0.00	45	22	32.84	4	0	0.00	15	7	31.82
CEACAMP10	0	genome.wustl.edu	37	19	43752792	43752792	+	R	SNP	T	T	C			TCGA-3B-A9HI-01A-11D-A387-09	TCGA-3B-A9HI-10A-01D-A38A-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c7768147-81e0-42bd-aa71-2a835e66dbe4	e6bb0106-9ac8-4f88-b90b-01e3b3269f2f	19	43752792	43752792	T	C	SNP	CEACAMP10	ENST00000489959	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.003	-	-	-	no_errors	CEACAMP10	HGNC	ENSG00000241104	tier1	-	-	34	0	0.00	31	16	34.04	8	0	0.00	14	4	22.22
PCSK9	0	genome.wustl.edu	37	1	55523034	55523034	+	Missense_Mutation	SNP	G	G	T			TCGA-3B-A9HI-01A-11D-A387-09	TCGA-3B-A9HI-10A-01D-A38A-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c7768147-81e0-42bd-aa71-2a835e66dbe4	e6bb0106-9ac8-4f88-b90b-01e3b3269f2f	1	55523034	55523034	G	T	SNP	PCSK9	ENST00000302118	human	ensembl	74_37	+1	known	missense	c.1027	p.D343Y	1.000	pfam_Peptidase_S8/S53_dom,superfamily_Peptidase_S8/S53_dom	pfam_Peptidase_S8/S53_dom,pfam_Inhibitor_I9,superfamily_Peptidase_S8/S53_dom,superfamily_Prot_inh_propept,prints_Peptidase_S8_subtilisin-rel	-	no_errors	PCSK9	HGNC	ENSG00000169174	tier1	-	-	55	0	0.00	69	21	23.33	53	0	0.00	106	21	16.54
GGCX	0	genome.wustl.edu	37	2	85780578	85780578	+	Missense_Mutation	SNP	C	C	T			TCGA-3B-A9HI-01A-11D-A387-09	TCGA-3B-A9HI-10A-01D-A38A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c7768147-81e0-42bd-aa71-2a835e66dbe4	e6bb0106-9ac8-4f88-b90b-01e3b3269f2f	2	85780578	85780578	C	T	SNP	GGCX	ENST00000233838	human	ensembl	74_37	-1	known	missense	c.932	p.C311Y	1.000	pfam_VKG_COase,smart_HTTM	pfam_VKG_COase,superfamily_RmlC_Cupin,smart_HTTM	-	no_errors	GGCX	HGNC	ENSG00000115486	tier1	-	-	12	0	0.00	12	6	33.33	27	0	0.00	42	12	22.22
CHD9	0	genome.wustl.edu	37	16	53191180	53191180	+	Silent	SNP	A	A	G			TCGA-3B-A9HI-01A-11D-A387-09	TCGA-3B-A9HI-10A-01D-A38A-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c7768147-81e0-42bd-aa71-2a835e66dbe4	e6bb0106-9ac8-4f88-b90b-01e3b3269f2f	16	53191180	53191180	A	G	SNP	CHD9	ENST00000398510	human	ensembl	74_37	+1	known	silent	c.1179	p.Q393	1.000	NULL	pfam_SNF2_N,pfam_BRK_domain,pfam_Chromo_domain,pfam_Helicase_C,pfam_D/R_helicase_DEAD/DEAH_N,superfamily_P-loop_NTPase,superfamily_Chromodomain-like,smart_Chromo_domain/shadow,smart_Helicase_ATP-bd,smart_Helicase_C,smart_BRK_domain,pfscan_Helicase_ATP-bd,pfscan_Helicase_C,pfscan_Chromo_domain/shadow	-	no_errors	CHD9	HGNC	ENSG00000177200	tier1	-	-	45	0	0.00	28	34	54.84	39	0	0.00	44	27	38.03
DGCR2	0	genome.wustl.edu	37	22	19055725	19055725	+	Silent	SNP	C	C	T			TCGA-3B-A9HI-01A-11D-A387-09	TCGA-3B-A9HI-10A-01D-A38A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c7768147-81e0-42bd-aa71-2a835e66dbe4	e6bb0106-9ac8-4f88-b90b-01e3b3269f2f	22	19055725	19055725	C	T	SNP	DGCR2	ENST00000263196	human	ensembl	74_37	-1	known	silent	c.216	p.E72	0.047	superfamily_LDrepeatLR_classA_rpt	pfam_LDrepeatLR_classA_rpt,superfamily_C-type_lectin_fold,superfamily_LDrepeatLR_classA_rpt,smart_LDrepeatLR_classA_rpt,smart_C-type_lectin,smart_VWF_C,pfscan_LDrepeatLR_classA_rpt,pfscan_C-type_lectin	-	no_errors	DGCR2	HGNC	ENSG00000070413	tier1	-	-	51	0	0.00	77	46	37.40	55	0	0.00	47	11	18.97
RARS	0	genome.wustl.edu	37	5	167929104	167929104	+	Missense_Mutation	SNP	G	G	C			TCGA-3B-A9HI-01A-11D-A387-09	TCGA-3B-A9HI-10A-01D-A38A-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c7768147-81e0-42bd-aa71-2a835e66dbe4	e6bb0106-9ac8-4f88-b90b-01e3b3269f2f	5	167929104	167929104	G	C	SNP	RARS	ENST00000231572	human	ensembl	74_37	+1	known	missense	c.1051	p.D351H	1.000	pfam_Arg-tR-synth_Ia_core,tigrfam_Arg-tR-ligase_Ia	pfam_Arg-tR-synth_Ia_core,pfam_DALR_anticod-bd,pfam_Arg-tR-synth_N,superfamily_tRsynth_1a_anticodon-bd,superfamily_Arg-tR-synth_N,smart_DALR_anticod-bd,prints_Arg-tR-synth_Ia_core,tigrfam_Arg-tR-ligase_Ia	-	no_errors	RARS	HGNC	ENSG00000113643	tier1	-	-	66	0	0.00	63	11	14.67	32	0	0.00	67	11	14.10
CHST8	0	genome.wustl.edu	37	19	34263881	34263881	+	Silent	SNP	G	G	A			TCGA-3B-A9HI-01A-11D-A387-09	TCGA-3B-A9HI-10A-01D-A38A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c7768147-81e0-42bd-aa71-2a835e66dbe4	e6bb0106-9ac8-4f88-b90b-01e3b3269f2f	19	34263881	34263881	G	A	SNP	CHST8	ENST00000262622	human	ensembl	74_37	+1	known	silent	c.1188	p.S396	0.000	pfam_Sulfotransferase	pfam_Sulfotransferase	-	no_errors	CHST8	HGNC	ENSG00000124302	tier1	-	-	44	0	0.00	41	30	42.25	60	0	0.00	87	45	34.09
RSBN1	0	genome.wustl.edu	37	1	114308661	114308661	+	Frame_Shift_Del	DEL	T	T	-			TCGA-3B-A9HI-01A-11D-A387-09	TCGA-3B-A9HI-10A-01D-A38A-09	T	T	T	-	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c7768147-81e0-42bd-aa71-2a835e66dbe4	e6bb0106-9ac8-4f88-b90b-01e3b3269f2f	1	114308661	114308661	T	-	DEL	RSBN1	ENST00000261441	human	ensembl	74_37	-1	known	frame_shift_del	c.2350	p.S784fs	1.000	NULL	NULL	-	no_errors	RSBN1	HGNC	ENSG00000081019	tier1			81	0	0.00	79	22	21.78	59	0	0.00	79	23	22.55
PRKCG	0	genome.wustl.edu	37	19	54409605	54409605	+	Nonsense_Mutation	SNP	C	C	A			TCGA-3B-A9HI-01A-11D-A387-09	TCGA-3B-A9HI-10A-01D-A38A-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c7768147-81e0-42bd-aa71-2a835e66dbe4	e6bb0106-9ac8-4f88-b90b-01e3b3269f2f	19	54409605	54409605	C	A	SNP	PRKCG	ENST00000540413	human	ensembl	74_37	+1	known	nonsense	c.1799	p.S600*	0.810	superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,pirsf_Protein_kinase_C_a/b/g,pfscan_Prot_kinase_dom	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_Kinase_C-like_PE/DAG-bd,pfam_C2_dom,pfam_Pkinase_C,superfamily_Kinase-like_dom,superfamily_C2_dom,smart_Prot_Kinase_C-like_PE/DAG-bd,smart_C2_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,smart_AGC-kinase_C,pirsf_Protein_kinase_C_a/b/g,prints_DAG/PE-bd,prints_C2_dom,pfscan_C2_dom,pfscan_Prot_Kinase_C-like_PE/DAG-bd,pfscan_Prot_kinase_dom	-	no_errors	PRKCG	HGNC	ENSG00000126583	tier1	-	-	52	0	0.00	97	12	11.01	72	0	0.00	106	7	6.19
DOCK9	0	genome.wustl.edu	37	13	99461377	99461377	+	Silent	SNP	C	C	T			TCGA-3B-A9HI-01A-11D-A387-09	TCGA-3B-A9HI-10A-01D-A38A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c7768147-81e0-42bd-aa71-2a835e66dbe4	e6bb0106-9ac8-4f88-b90b-01e3b3269f2f	13	99461377	99461377	C	T	SNP	DOCK9	ENST00000376460	human	ensembl	74_37	-1	known	silent	c.5373	p.A1791	1.000	NULL	pfam_DOCK_C,pfam_DOCK_C/D_N,pfam_Pleckstrin_homology,superfamily_ARM-type_fold,smart_Pleckstrin_homology,pfscan_Pleckstrin_homology	-	no_errors	DOCK9	HGNC	ENSG00000088387	tier1	-	-	39	0	0.00	60	7	10.45	27	0	0.00	80	7	8.05
HAPLN3	0	genome.wustl.edu	37	15	89436251	89436251	+	Missense_Mutation	SNP	A	A	T			TCGA-3B-A9HI-01A-11D-A387-09	TCGA-3B-A9HI-10A-01D-A38A-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c7768147-81e0-42bd-aa71-2a835e66dbe4	e6bb0106-9ac8-4f88-b90b-01e3b3269f2f	15	89436251	89436251	A	T	SNP	HAPLN3	ENST00000562889	human	ensembl	74_37	-1	novel	missense	c.93	p.S31R	0.000	NULL	pfam_Link,pfam_Ig_V-set,superfamily_C-type_lectin_fold,smart_Ig_sub,smart_Ig_V-set_subgr,smart_Link,pfscan_Link,pfscan_Ig-like_dom,prints_Link	-	no_errors	HAPLN3	HGNC	ENSG00000140511	tier1	-	-	52	0	0.00	49	5	9.26	114	0	0.00	115	9	7.20
RASGEF1C	0	genome.wustl.edu	37	5	179564684	179564684	+	Missense_Mutation	SNP	C	C	A			TCGA-3B-A9HI-01A-11D-A387-09	TCGA-3B-A9HI-10A-01D-A38A-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c7768147-81e0-42bd-aa71-2a835e66dbe4	e6bb0106-9ac8-4f88-b90b-01e3b3269f2f	5	179564684	179564684	C	A	SNP	RASGEF1C	ENST00000361132	human	ensembl	74_37	-1	known	missense	c.206	p.S69I	1.000	pfam_Ras-like_Gua-exchang_fac_N,superfamily_Ras_GEF_dom,pfscan_Ras-like_Gua-exchang_fac_N	pfam_RasGRF_CDC25,pfam_Ras-like_Gua-exchang_fac_N,superfamily_Ras_GEF_dom,smart_RasGRF_CDC25,pfscan_RasGRF_CDC25,pfscan_Ras-like_Gua-exchang_fac_N	-	no_errors	RASGEF1C	HGNC	ENSG00000146090	tier1	-	-	26	0	0.00	32	8	20.00	44	1	2.22	65	17	20.73
PARG	0	genome.wustl.edu	37	10	51041063	51041064	+	R	INS	-	-	T			TCGA-3B-A9HI-01A-11D-A387-09	TCGA-3B-A9HI-10A-01D-A38A-09	-	-	-	T	-	-	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c7768147-81e0-42bd-aa71-2a835e66dbe4	e6bb0106-9ac8-4f88-b90b-01e3b3269f2f	10	51041063	51041064	-	T	INS	PARG	ENST00000492350	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000:0.000	-	-	-	no_errors	PARG	HGNC	ENSG00000227345	tier1			20	0	0.00	22	3	12.00	33	1	2.94	64	9	12.33
ENSG00000266156	0	genome.wustl.edu	37	19	20988369	20988370	+	R	INS	-	-	T			TCGA-3B-A9HI-01A-11D-A387-09	TCGA-3B-A9HI-10A-01D-A38A-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	c7768147-81e0-42bd-aa71-2a835e66dbe4	e6bb0106-9ac8-4f88-b90b-01e3b3269f2f	19	20988369	20988370	-	T	INS	ENSG00000266156	ENST00000582722	human	ensembl	74_37	+1	novel	rna	NULL	NULL	0.000:0.001	-	-	-	no_errors	AC010329.1	Clone_based_ensembl_gene	ENSG00000266156	tier1			13	0	0.00	16	2	11.11	8	0	0.00	6	0	0.00
OBSCN	0	genome.wustl.edu	37	1	228451874	228451874	+	Missense_Mutation	SNP	C	C	T			TCGA-3B-A9HI-01A-11D-A387-09	TCGA-3B-A9HI-10A-01D-A38A-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	c7768147-81e0-42bd-aa71-2a835e66dbe4	e6bb0106-9ac8-4f88-b90b-01e3b3269f2f	1	228451874	228451874	C	T	SNP	OBSCN	ENST00000422127	human	ensembl	74_37	+1	known	missense	c.4643	p.A1548V	0.000	pfam_Ig_I-set,smart_Ig_sub,smart_Ig_sub2,pfscan_Ig-like_dom	pfam_Ig_I-set,pfam_Immunoglobulin,pfam_Ig_V-set,pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Fibronectin_type3,pfam_DH-domain,pfam_IQ_motif_EF-hand-BS,superfamily_Kinase-like_dom,superfamily_DH-domain,superfamily_Fibronectin_type3,superfamily_SH3_domain,smart_Ig_sub,smart_Ig_sub2,smart_Ig_V-set_subgr,smart_Fibronectin_type3,smart_IQ_motif_EF-hand-BS,smart_DH-domain,smart_Pleckstrin_homology,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Fibronectin_type3,pfscan_IQ_motif_EF-hand-BS,pfscan_Pleckstrin_homology,pfscan_Prot_kinase_dom,pfscan_Ig-like_dom,pfscan_DH-domain	-	no_errors	OBSCN	HGNC	ENSG00000154358	tier1	-	-	137	0	0.00	104	29	21.80	5	0	0.00	0	1	100.00
AGGF1	0	genome.wustl.edu	37	5	76332520	76332520	+	Missense_Mutation	SNP	A	A	G			TCGA-3B-A9HI-01A-11D-A387-09	TCGA-3B-A9HI-10A-01D-A38A-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	c7768147-81e0-42bd-aa71-2a835e66dbe4	e6bb0106-9ac8-4f88-b90b-01e3b3269f2f	5	76332520	76332520	A	G	SNP	AGGF1	ENST00000312916	human	ensembl	74_37	+1	known	missense	c.656	p.H219R	1.000	NULL	pfam_FHA_dom,pfam_G_patch_dom,superfamily_SMAD_FHA_domain,smart_FHA_dom,smart_G_patch_dom,pfscan_FHA_dom,pfscan_G_patch_dom	-	no_errors	AGGF1	HGNC	ENSG00000164252	tier1	-	-	50	0	0.00	35	17	32.69	0	0	0.00	0	0	0.00
APC2	0	genome.wustl.edu	37	9	140070016	140070016	+	R	SNP	G	G	C			TCGA-3B-A9HI-01A-11D-A387-09	TCGA-3B-A9HI-10A-01D-A38A-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	c7768147-81e0-42bd-aa71-2a835e66dbe4	e6bb0106-9ac8-4f88-b90b-01e3b3269f2f	9	140070016	140070016	G	C	SNP	APC2	ENST00000483432	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	APC2	HGNC	ENSG00000176248	tier1	-	-	55	0	0.00	71	12	14.29	1	0	0.00	2	0	0.00
ENSG00000237357	0	genome.wustl.edu	37	9	44403192	44403192	+	R	SNP	C	C	G			TCGA-3B-A9HI-01A-11D-A387-09	TCGA-3B-A9HI-10A-01D-A38A-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	c7768147-81e0-42bd-aa71-2a835e66dbe4	e6bb0106-9ac8-4f88-b90b-01e3b3269f2f	9	44403192	44403192	C	G	SNP	ENSG00000237357	ENST00000425309	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.242	-	-	-	no_errors	RP11-475I24.3	Clone_based_vega_gene	ENSG00000237357	tier1	-	-	40	0	0.00	53	8	13.11	0	0	0.00	0	0	0.00
JPH1	0	genome.wustl.edu	37	8	75227796	75227796	+	Missense_Mutation	SNP	C	C	T			TCGA-3B-A9HI-01A-11D-A387-09	TCGA-3B-A9HI-10A-01D-A38A-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	c7768147-81e0-42bd-aa71-2a835e66dbe4	e6bb0106-9ac8-4f88-b90b-01e3b3269f2f	8	75227796	75227796	C	T	SNP	JPH1	ENST00000342232	human	ensembl	74_37	-1	known	missense	c.439	p.V147M	1.000	smart_MORN,pirsf_Junctophilin	pfam_MORN,smart_MORN,pirsf_Junctophilin	-	no_errors	JPH1	HGNC	ENSG00000104369	tier1	-	-	20	0	0.00	12	3	20.00	3	0	0.00	4	0	0.00
SPPL2B	0	genome.wustl.edu	37	19	2341094	2341101	+	R	DEL	CTCCCTGG	CTCCCTGG	-			TCGA-3B-A9HI-01A-11D-A387-09	TCGA-3B-A9HI-10A-01D-A38A-09	CTCCCTGG	CTCCCTGG					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	c7768147-81e0-42bd-aa71-2a835e66dbe4	e6bb0106-9ac8-4f88-b90b-01e3b3269f2f	19	2341094	2341101	CTCCCTGG	-	DEL	SPPL2B	ENST00000592738	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.000:0.000:0.010:0.001:0.000:0.000:0.001:0.000	-	-	-	no_errors	SPPL2B	HGNC	ENSG00000005206	tier1			0	0	0.00	1	0	0.00	0	0	0.00	1	0	0.00