Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	default_gene_name	gene_name_source	 ensembl_gene_id	tier	dbSNP	GMAF	n_ref_count	n_alt_count	normal_vaf	t_ref_count	t_alt_count	tumor_vaf	n_ref_count_val	n_alt_count_val	normal_vaf_val	t_ref_count_val	t_alt_count_val	tumor_vaf_val
DSCAM	0	genome.wustl.edu	37	21	41385063	41385063	+	Silent	SNP	C	C	G			TCGA-3B-A9HU-01A-11D-A38Z-09	TCGA-3B-A9HU-10A-01D-A38Z-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67fce992-e09f-4bde-b216-e9516a3bf796	74be41ea-729b-4b31-8c99-add92e25b393	21	41385063	41385063	C	G	SNP	DSCAM	ENST00000400454	human	ensembl	74_37	-1	known	silent	c.5937	p.L1979	1.000	NULL	pfam_Ig_I-set,pfam_Fibronectin_type3,pfam_Immunoglobulin,pfam_Ig_V-set,superfamily_Fibronectin_type3,smart_Ig_sub2,smart_Ig_sub,smart_Ig_V-set_subgr,smart_Fibronectin_type3,pfscan_Fibronectin_type3,pfscan_Ig-like_dom	-	no_errors	DSCAM	HGNC	ENSG00000171587	tier1	-	-	56	0	0.00	33	27	45.00	47	0	0.00	53	22	29.33
COL5A3	0	genome.wustl.edu	37	19	10083634	10083634	+	Missense_Mutation	SNP	C	C	G			TCGA-3B-A9HU-01A-11D-A38Z-09	TCGA-3B-A9HU-10A-01D-A38Z-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67fce992-e09f-4bde-b216-e9516a3bf796	74be41ea-729b-4b31-8c99-add92e25b393	19	10083634	10083634	C	G	SNP	COL5A3	ENST00000264828	human	ensembl	74_37	-1	known	missense	c.3735	p.K1245N	1.000	NULL	pfam_Collagen,pfam_Fib_collagen_C,superfamily_ConA-like_lec_gl_sf,smart_Laminin_G,smart_Fib_collagen_C	-	no_errors	COL5A3	HGNC	ENSG00000080573	tier1	-	-	79	0	0.00	66	22	25.00	59	0	0.00	71	22	23.66
CHST1	0	genome.wustl.edu	37	11	45671339	45671339	+	Missense_Mutation	SNP	C	C	T			TCGA-3B-A9HU-01A-11D-A38Z-09	TCGA-3B-A9HU-10A-01D-A38Z-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67fce992-e09f-4bde-b216-e9516a3bf796	74be41ea-729b-4b31-8c99-add92e25b393	11	45671339	45671339	C	T	SNP	CHST1	ENST00000308064	human	ensembl	74_37	-1	known	missense	c.1135	p.V379M	1.000	pfam_Sulfotransferase_dom,superfamily_P-loop_NTPase,pirsf_Carbohydrate_sulfotransferase	pfam_Sulfotransferase_dom,superfamily_P-loop_NTPase,pirsf_Carbohydrate_sulfotransferase	-	no_errors	CHST1	HGNC	ENSG00000175264	tier1	-	-	91	0	0.00	57	25	30.49	19	0	0.00	12	8	40.00
BAALC	0	genome.wustl.edu	37	8	104210364	104210364	+	Missense_Mutation	SNP	G	G	C			TCGA-3B-A9HU-01A-11D-A38Z-09	TCGA-3B-A9HU-10A-01D-A38Z-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67fce992-e09f-4bde-b216-e9516a3bf796	74be41ea-729b-4b31-8c99-add92e25b393	8	104210364	104210364	G	C	SNP	BAALC	ENST00000330955	human	ensembl	74_37	+1	putative	missense	c.198	p.Q66H	0.011	NULL	pfam_BAALC	-	no_errors	BAALC	HGNC	ENSG00000164929	tier1	-	-	59	0	0.00	61	20	24.69	86	0	0.00	92	35	27.56
INTS4L1	0	genome.wustl.edu	37	7	64613446	64613446	+	R	SNP	G	G	A			TCGA-3B-A9HU-01A-11D-A38Z-09	TCGA-3B-A9HU-10A-01D-A38Z-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67fce992-e09f-4bde-b216-e9516a3bf796	74be41ea-729b-4b31-8c99-add92e25b393	7	64613446	64613446	G	A	SNP	INTS4L1	ENST00000587624	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.915	-	-	-	no_errors	INTS4L1	HGNC	ENSG00000164669	tier1	-	-	55	0	0.00	52	19	26.76	17	0	0.00	28	7	20.00
ENSG00000260628	0	genome.wustl.edu	37	16	31993507	31993507	+	R	SNP	C	C	T			TCGA-3B-A9HU-01A-11D-A38Z-09	TCGA-3B-A9HU-10A-01D-A38Z-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67fce992-e09f-4bde-b216-e9516a3bf796	74be41ea-729b-4b31-8c99-add92e25b393	16	31993507	31993507	C	T	SNP	ENSG00000260628	ENST00000568570	human	ensembl	74_37	+1	known	rna	NULL	NULL	1.000	-	-	-	no_errors	RP11-1166P10.1	Clone_based_vega_gene	ENSG00000260628	tier1	-	-	37	0	0.00	42	16	27.59	18	0	0.00	17	7	29.17
EPHA8	0	genome.wustl.edu	37	1	22927488	22927488	+	Missense_Mutation	SNP	G	G	A			TCGA-3B-A9HU-01A-11D-A38Z-09	TCGA-3B-A9HU-10A-01D-A38Z-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67fce992-e09f-4bde-b216-e9516a3bf796	74be41ea-729b-4b31-8c99-add92e25b393	1	22927488	22927488	G	A	SNP	EPHA8	ENST00000166244	human	ensembl	74_37	+1	known	missense	c.2636	p.R879Q	1.000	pirsf_Tyr_kinase_ephrin_rcpt,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_kinase_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,prints_Ser-Thr/Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	pirsf_Tyr_kinase_ephrin_rcpt,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Ephrin_rcpt_lig-bd_dom,pfam_Prot_kinase_dom,pfam_Fibronectin_type3,pfam_SAM_type1,pfam_SAM_2,superfamily_Galactose-bd-like,superfamily_Kinase-like_dom,superfamily_Fibronectin_type3,superfamily_SAM/pointed,superfamily_Growth_fac_rcpt_N_dom,smart_Ephrin_rcpt_lig-bd_dom,smart_Fibronectin_type3,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,smart_SAM,prints_Ser-Thr/Tyr_kinase_cat_dom,pfscan_Fibronectin_type3,pfscan_SAM,pfscan_Prot_kinase_dom	-	no_errors	EPHA8	HGNC	ENSG00000070886	tier1	rs146856523	-	31	0	0.00	33	14	29.79	12	0	0.00	11	4	26.67
ENSG00000222033	0	genome.wustl.edu	37	2	171570607	171570607	+	Missense_Mutation	SNP	G	G	T			TCGA-3B-A9HU-01A-11D-A38Z-09	TCGA-3B-A9HU-10A-01D-A38Z-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67fce992-e09f-4bde-b216-e9516a3bf796	74be41ea-729b-4b31-8c99-add92e25b393	2	171570607	171570607	G	T	SNP	ENSG00000222033	ENST00000409786	human	ensembl	74_37	-1	novel	missense	c.347	p.A116E	0.000	NULL	NULL	-	no_errors	AC007405.2	Clone_based_vega_gene	ENSG00000222033	tier1	-	-	26	0	0.00	12	7	36.84	18	0	0.00	12	7	36.84
OR13D1	0	genome.wustl.edu	37	9	107457047	107457047	+	Silent	SNP	T	T	A			TCGA-3B-A9HU-01A-11D-A38Z-09	TCGA-3B-A9HU-10A-01D-A38Z-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67fce992-e09f-4bde-b216-e9516a3bf796	74be41ea-729b-4b31-8c99-add92e25b393	9	107457047	107457047	T	A	SNP	OR13D1	ENST00000318763	human	ensembl	74_37	+1	known	silent	c.345	p.I115	0.000	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR13D1	HGNC	ENSG00000179055	tier1	-	-	36	0	0.00	30	18	37.50	73	0	0.00	106	29	21.48
MYH10	0	genome.wustl.edu	37	17	8422225	8422225	+	Missense_Mutation	SNP	C	C	A			TCGA-3B-A9HU-01A-11D-A38Z-09	TCGA-3B-A9HU-10A-01D-A38Z-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67fce992-e09f-4bde-b216-e9516a3bf796	74be41ea-729b-4b31-8c99-add92e25b393	17	8422225	8422225	C	A	SNP	MYH10	ENST00000396239	human	ensembl	74_37	-1	known	missense	c.2287	p.D763Y	1.000	pfam_Myosin_head_motor_dom,superfamily_P-loop_NTPase,smart_Myosin_head_motor_dom	pfam_Myosin_head_motor_dom,pfam_Myosin_tail,pfam_Myosin_N,pfam_IQ_motif_EF-hand-BS,superfamily_P-loop_NTPase,superfamily_Prefoldin,superfamily_HR1_rho-bd,superfamily_UBA-like,smart_Myosin_head_motor_dom,smart_IQ_motif_EF-hand-BS,pfscan_IQ_motif_EF-hand-BS,prints_Myosin_head_motor_dom	-	no_errors	MYH10	HGNC	ENSG00000133026	tier1	-	-	141	0	0.00	111	54	32.73	134	0	0.00	145	57	28.22
TP53	0	genome.wustl.edu	37	17	7577498	7577498	+	Splice_Site	SNP	C	C	T			TCGA-3B-A9HU-01A-11D-A38Z-09	TCGA-3B-A9HU-10A-01D-A38Z-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67fce992-e09f-4bde-b216-e9516a3bf796	74be41ea-729b-4b31-8c99-add92e25b393	17	7577498	7577498	C	T	SNP	TP53	ENST00000269305	human	ensembl	74_37	-1	known	splice_site	c.782+1	e6+1	1.000	-	-	-	no_errors	TP53	HGNC	ENSG00000141510	tier1	-	-	26	0	0.00	11	21	65.62	76	0	0.00	40	24	37.50
KIF4B	0	genome.wustl.edu	37	5	154395666	154395666	+	Silent	SNP	T	T	C			TCGA-3B-A9HU-01A-11D-A38Z-09	TCGA-3B-A9HU-10A-01D-A38Z-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67fce992-e09f-4bde-b216-e9516a3bf796	74be41ea-729b-4b31-8c99-add92e25b393	5	154395666	154395666	T	C	SNP	KIF4B	ENST00000435029	human	ensembl	74_37	+1	known	silent	c.2247	p.N749	1.000	NULL	pfam_Kinesin_motor_dom,superfamily_P-loop_NTPase,smart_Kinesin_motor_dom,pfscan_Kinesin_motor_dom,prints_Kinesin_motor_dom	-	no_errors	KIF4B	HGNC	ENSG00000226650	tier1	-	-	112	0	0.00	80	35	30.43	36	0	0.00	29	20	40.82
DJC5B	0	genome.wustl.edu	37	8	66963819	66963819	+	Silent	SNP	C	C	T			TCGA-3B-A9HU-01A-11D-A38Z-09	TCGA-3B-A9HU-10A-01D-A38Z-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67fce992-e09f-4bde-b216-e9516a3bf796	74be41ea-729b-4b31-8c99-add92e25b393	8	66963819	66963819	C	T	SNP	DJC5B	ENST00000276570	human	ensembl	74_37	+1	known	silent	c.37	p.L13	0.000	superfamily_DnaJ_domain	pfam_DnaJ_domain,superfamily_DnaJ_domain,smart_DnaJ_domain,pfscan_DnaJ_domain,prints_DnaJ_domain	-	no_errors	DJC5B	HGNC	ENSG00000147570	tier1	-	-	47	0	0.00	50	27	35.06	131	0	0.00	105	39	26.90
MARCO	0	genome.wustl.edu	37	2	119739778	119739778	+	Silent	SNP	A	A	G			TCGA-3B-A9HU-01A-11D-A38Z-09	TCGA-3B-A9HU-10A-01D-A38Z-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67fce992-e09f-4bde-b216-e9516a3bf796	74be41ea-729b-4b31-8c99-add92e25b393	2	119739778	119739778	A	G	SNP	MARCO	ENST00000327097	human	ensembl	74_37	+1	known	silent	c.948	p.G316	0.284	NULL	pfam_Collagen,pfam_SRCR,superfamily_Srcr_rcpt-rel,smart_Srcr_rcpt-rel,pfscan_SRCR,prints_SRCR	-	no_errors	MARCO	HGNC	ENSG00000019169	tier1	-	-	36	0	0.00	29	13	30.95	33	0	0.00	35	17	32.69
RNF125	0	genome.wustl.edu	37	18	29648343	29648343	+	Missense_Mutation	SNP	C	C	A			TCGA-3B-A9HU-01A-11D-A38Z-09	TCGA-3B-A9HU-10A-01D-A38Z-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67fce992-e09f-4bde-b216-e9516a3bf796	74be41ea-729b-4b31-8c99-add92e25b393	18	29648343	29648343	C	A	SNP	RNF125	ENST00000217740	human	ensembl	74_37	+1	known	missense	c.695	p.T232K	1.000	NULL	pfam_Znf_C3HC4_RING-type,smart_Znf_RING,pfscan_Znf_RING	-	no_errors	RNF125	HGNC	ENSG00000101695	tier1	-	-	114	0	0.00	59	38	39.18	139	0	0.00	135	60	30.77
ADAM11	0	genome.wustl.edu	37	17	42852679	42852679	+	Missense_Mutation	SNP	G	G	T			TCGA-3B-A9HU-01A-11D-A38Z-09	TCGA-3B-A9HU-10A-01D-A38Z-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67fce992-e09f-4bde-b216-e9516a3bf796	74be41ea-729b-4b31-8c99-add92e25b393	17	42852679	42852679	G	T	SNP	ADAM11	ENST00000200557	human	ensembl	74_37	+1	known	missense	c.1320	p.K440N	1.000	NULL	pfam_Peptidase_M12B,pfam_Peptidase_M12B_N,pfam_ADAM_Cys-rich,pfam_Blood-coag_inhib_Disintegrin,superfamily_Blood-coag_inhib_Disintegrin,smart_Blood-coag_inhib_Disintegrin,smart_ADAM_Cys-rich,prints_Blood-coag_inhib_Disintegrin,pfscan_Blood-coag_inhib_Disintegrin,pfscan_EG-like_dom,pfscan_Peptidase_M12B	-	no_errors	ADAM11	HGNC	ENSG00000073670	tier1	-	-	61	0	0.00	57	18	24.00	45	0	0.00	59	18	23.38
SIDT2	0	genome.wustl.edu	37	11	117053257	117053257	+	Missense_Mutation	SNP	A	A	C			TCGA-3B-A9HU-01A-11D-A38Z-09	TCGA-3B-A9HU-10A-01D-A38Z-09	A	A	A	C	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67fce992-e09f-4bde-b216-e9516a3bf796	74be41ea-729b-4b31-8c99-add92e25b393	11	117053257	117053257	A	C	SNP	SIDT2	ENST00000278951	human	ensembl	74_37	+1	known	missense	c.539	p.E180A	0.996	NULL	NULL	-	no_errors	SIDT2	HGNC	ENSG00000149577	tier1	-	-	62	0	0.00	29	15	34.09	127	0	0.00	88	31	26.05
RC3H2	0	genome.wustl.edu	37	9	125627715	125627715	+	Missense_Mutation	SNP	C	C	A			TCGA-3B-A9HU-01A-11D-A38Z-09	TCGA-3B-A9HU-10A-01D-A38Z-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67fce992-e09f-4bde-b216-e9516a3bf796	74be41ea-729b-4b31-8c99-add92e25b393	9	125627715	125627715	C	A	SNP	RC3H2	ENST00000357244	human	ensembl	74_37	-1	known	missense	c.1547	p.R516I	1.000	NULL	pfam_Znf_CCCH,smart_Znf_RING,smart_Znf_CCCH,pfscan_Znf_RING	-	no_errors	RC3H2	HGNC	ENSG00000056586	tier1	-	-	116	0	0.00	63	26	29.21	141	0	0.00	117	47	28.66
GPR78	0	genome.wustl.edu	37	4	8588802	8588802	+	Silent	SNP	C	C	T			TCGA-3B-A9HU-01A-11D-A38Z-09	TCGA-3B-A9HU-10A-01D-A38Z-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67fce992-e09f-4bde-b216-e9516a3bf796	74be41ea-729b-4b31-8c99-add92e25b393	4	8588802	8588802	C	T	SNP	GPR78	ENST00000382487	human	ensembl	74_37	+1	known	silent	c.804	p.F268	0.009	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_GPCR_Rhodpsn	-	no_errors	GPR78	HGNC	ENSG00000155269	tier1	-	-	107	0	0.00	79	22	21.78	27	0	0.00	20	16	43.24
SP91	0	genome.wustl.edu	37	6	84368742	84368742	+	Silent	SNP	T	T	C			TCGA-3B-A9HU-01A-11D-A38Z-09	TCGA-3B-A9HU-10A-01D-A38Z-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67fce992-e09f-4bde-b216-e9516a3bf796	74be41ea-729b-4b31-8c99-add92e25b393	6	84368742	84368742	T	C	SNP	SP91	ENST00000369694	human	ensembl	74_37	-1	known	silent	c.522	p.Q174	0.998	pfam_ANTH_dom	pfam_ANTH_dom,pfam_Epsin_dom_N,superfamily_ENTH_VHS,smart_Epsin-like_N,pfscan_Epsin-like_N	-	no_errors	SP91	HGNC	ENSG00000065609	tier1	-	-	61	0	0.00	41	11	21.15	76	0	0.00	77	23	22.77
FAM167A	0	genome.wustl.edu	37	8	11280926	11280926	+	R	SNP	G	G	A			TCGA-3B-A9HU-01A-11D-A38Z-09	TCGA-3B-A9HU-10A-01D-A38Z-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67fce992-e09f-4bde-b216-e9516a3bf796	74be41ea-729b-4b31-8c99-add92e25b393	8	11280926	11280926	G	A	SNP	FAM167A	ENST00000531564	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.006	-	-	-	no_errors	FAM167A	HGNC	ENSG00000154319	tier1	-	-	43	0	0.00	41	4	8.89	70	0	0.00	83	36	30.25
DH7	0	genome.wustl.edu	37	2	196709754	196709754	+	Missense_Mutation	SNP	A	A	G			TCGA-3B-A9HU-01A-11D-A38Z-09	TCGA-3B-A9HU-10A-01D-A38Z-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67fce992-e09f-4bde-b216-e9516a3bf796	74be41ea-729b-4b31-8c99-add92e25b393	2	196709754	196709754	A	G	SNP	DH7	ENST00000312428	human	ensembl	74_37	-1	known	missense	c.8917	p.F2973L	0.997	NULL	pfam_Dynein_heavy_dom,pfam_Dynein_heavy_dom-2,superfamily_P-loop_NTPase,superfamily_Signal_recog_particle_SRP9/14,smart_AAA+_ATPase,pfscan_EF_hand_dom	-	no_errors	DH7	HGNC	ENSG00000118997	tier1	-	-	119	0	0.00	81	40	33.06	61	0	0.00	77	32	29.36
CLMN	0	genome.wustl.edu	37	14	95669657	95669657	+	Missense_Mutation	SNP	C	C	T			TCGA-3B-A9HU-01A-11D-A38Z-09	TCGA-3B-A9HU-10A-01D-A38Z-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67fce992-e09f-4bde-b216-e9516a3bf796	74be41ea-729b-4b31-8c99-add92e25b393	14	95669657	95669657	C	T	SNP	CLMN	ENST00000298912	human	ensembl	74_37	-1	known	missense	c.2029	p.D677N	0.000	NULL	pfam_CH-domain,superfamily_CH-domain,smart_CH-domain,pfscan_CH-domain	-	no_errors	CLMN	HGNC	ENSG00000165959	tier1	-	-	28	0	0.00	35	5	12.50	71	0	0.00	84	28	25.00
FL	0	genome.wustl.edu	37	X	153590144	153590144	+	Silent	SNP	G	G	A			TCGA-3B-A9HU-01A-11D-A38Z-09	TCGA-3B-A9HU-10A-01D-A38Z-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67fce992-e09f-4bde-b216-e9516a3bf796	74be41ea-729b-4b31-8c99-add92e25b393	X	153590144	153590144	G	A	SNP	FL	ENST00000369850	human	ensembl	74_37	-1	known	silent	c.2838	p.G946	0.001	pfam_Filamin/ABP280_repeat-like,superfamily_Ig_E-set,smart_Filamin,pfscan_Filamin/ABP280_repeat-like	pfam_Filamin/ABP280_repeat-like,pfam_CH-domain,superfamily_CH-domain,superfamily_Ig_E-set,smart_CH-domain,smart_Filamin,pfscan_CH-domain,pfscan_Filamin/ABP280_repeat-like	-	no_errors	FL	HGNC	ENSG00000196924	tier1	-	-	37	0	0.00	22	10	31.25	66	0	0.00	74	27	26.73
APC5	0	genome.wustl.edu	37	12	121766222	121766222	+	Missense_Mutation	SNP	C	C	T			TCGA-3B-A9HU-01A-11D-A38Z-09	TCGA-3B-A9HU-10A-01D-A38Z-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67fce992-e09f-4bde-b216-e9516a3bf796	74be41ea-729b-4b31-8c99-add92e25b393	12	121766222	121766222	C	T	SNP	APC5	ENST00000261819	human	ensembl	74_37	-1	known	missense	c.1201	p.A401T	1.000	NULL	smart_TPR_repeat	-	no_errors	APC5	HGNC	ENSG00000089053	tier1	-	-	47	0	0.00	35	11	23.91	75	0	0.00	88	22	20.00
PRUNE2	0	genome.wustl.edu	37	9	79259430	79259430	+	R	SNP	G	G	A			TCGA-3B-A9HU-01A-11D-A38Z-09	TCGA-3B-A9HU-10A-01D-A38Z-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67fce992-e09f-4bde-b216-e9516a3bf796	74be41ea-729b-4b31-8c99-add92e25b393	9	79259430	79259430	G	A	SNP	PRUNE2	ENST00000488346	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	PRUNE2	HGNC	ENSG00000106772	tier1	-	-	15	0	0.00	11	4	26.67	63	0	0.00	83	15	15.15
DH8	0	genome.wustl.edu	37	6	38994431	38994431	+	Silent	SNP	G	G	T			TCGA-3B-A9HU-01A-11D-A38Z-09	TCGA-3B-A9HU-10A-01D-A38Z-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67fce992-e09f-4bde-b216-e9516a3bf796	74be41ea-729b-4b31-8c99-add92e25b393	6	38994431	38994431	G	T	SNP	DH8	ENST00000359357	human	ensembl	74_37	+1	known	silent	c.13173	p.T4391	0.000	pfam_Dynein_heavy_dom	pfam_Dynein_heavy_dom,pfam_Dynein_heavy_dom-1,pfam_Dynein_heavy_dom-2,pfam_ATPase_dyneun-rel_AAA,superfamily_P-loop_NTPase,smart_AAA+_ATPase	-	no_errors	DH8	HGNC	ENSG00000124721	tier1	-	-	28	0	0.00	31	7	18.42	77	0	0.00	70	40	36.36
GPR64	0	genome.wustl.edu	37	X	19014264	19014264	+	Frame_Shift_Del	DEL	A	A	-			TCGA-3B-A9HU-01A-11D-A38Z-09	TCGA-3B-A9HU-10A-01D-A38Z-09	A	A	A	-	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67fce992-e09f-4bde-b216-e9516a3bf796	74be41ea-729b-4b31-8c99-add92e25b393	X	19014264	19014264	A	-	DEL	GPR64	ENST00000379869	human	ensembl	74_37	-1	known	frame_shift_del	c.2621	p.F874fs	1.000	pfam_GPCR_2_secretin-like,pfscan_GPCR_2-like,prints_GPCR_2_secretin-like	pfam_GPCR_2_secretin-like,pfam_GPS_dom,smart_GPS_dom,pfscan_GPS_dom,pfscan_GPCR_2-like,prints_GPCR_2_secretin-like	-	no_errors	GPR64	HGNC	ENSG00000173698	tier1			257	0	0.00	342	69	16.79	90	0	0.00	220	49	18.22
MUC5B	0	genome.wustl.edu	37	11	1271489	1271489	+	Missense_Mutation	SNP	C	C	T			TCGA-3B-A9HU-01A-11D-A38Z-09	TCGA-3B-A9HU-10A-01D-A38Z-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67fce992-e09f-4bde-b216-e9516a3bf796	74be41ea-729b-4b31-8c99-add92e25b393	11	1271489	1271489	C	T	SNP	MUC5B	ENST00000447027	human	ensembl	74_37	+1	known	missense	c.13388	p.T4463M	0.001	NULL	pfam_VWF_type-D,pfam_Unchr_dom_Cys-rich,pfam_TIL_dom,pfam_VWF_C,superfamily_TIL_dom,smart_VWF_type-D,smart_Unchr_dom_Cys-rich,smart_VWC_out,smart_VWF_C,smart_Cys_knot_C,pfscan_Cys_knot_C,pfscan_VWF_C	-	no_errors	MUC5B	HGNC	ENSG00000117983	tier1	rs200985531	-	69	0	0.00	46	16	25.81	6	0	0.00	5	8	61.54
TRIM64C	0	genome.wustl.edu	37	11	49080482	49080482	+	Silent	SNP	C	C	T			TCGA-3B-A9HU-01A-11D-A38Z-09	TCGA-3B-A9HU-10A-01D-A38Z-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67fce992-e09f-4bde-b216-e9516a3bf796	74be41ea-729b-4b31-8c99-add92e25b393	11	49080482	49080482	C	T	SNP	TRIM64C	ENST00000530230	human	ensembl	74_37	-1	known	silent	c.183	p.K61	0.004	NULL	pfam_SPRY_rcpt,pfam_Znf_B-box,superfamily_ConA-like_lec_gl_sf,smart_Znf_B-box,smart_SPla/RYanodine_receptor_subgr,pfscan_B30.2/SPRY,pfscan_Znf_B-box,pfscan_Znf_RING,prints_Butyrophylin	-	no_errors	TRIM64C	HGNC	ENSG00000214891	tier1	-	-	141	1	0.70	129	12	8.51	31	0	0.00	37	4	9.76
SEMA3A	0	genome.wustl.edu	37	7	83591051	83591051	+	Missense_Mutation	SNP	G	G	A			TCGA-3B-A9HU-01A-11D-A38Z-09	TCGA-3B-A9HU-10A-01D-A38Z-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67fce992-e09f-4bde-b216-e9516a3bf796	74be41ea-729b-4b31-8c99-add92e25b393	7	83591051	83591051	G	A	SNP	SEMA3A	ENST00000265362	human	ensembl	74_37	-1	known	missense	c.1952	p.A651V	1.000	smart_Ig_sub,pfscan_Ig-like_dom	pfam_Semap_dom,superfamily_Semap_dom,superfamily_Plexin-like_fold,smart_Semap_dom,smart_Plexin-like_fold,smart_Ig_sub,pfscan_Semap_dom,pfscan_Ig-like_dom	-	no_errors	SEMA3A	HGNC	ENSG00000075213	tier1	rs150205475	GMAF=0.0005	58	0	0.00	55	14	20.29	103	1	0.96	152	13	7.88
LTC4S	0	genome.wustl.edu	37	5	179221116	179221116	+	Missense_Mutation	SNP	C	C	A			TCGA-3B-A9HU-01A-11D-A38Z-09	TCGA-3B-A9HU-10A-01D-A38Z-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67fce992-e09f-4bde-b216-e9516a3bf796	74be41ea-729b-4b31-8c99-add92e25b393	5	179221116	179221116	C	A	SNP	LTC4S	ENST00000292596	human	ensembl	74_37	+1	known	missense	c.35	p.T12N	1.000	pfam_Membr-assoc_MAPEG,prints_5_LipOase_AP	pfam_Membr-assoc_MAPEG,prints_5_LipOase_AP	-	no_errors	LTC4S	HGNC	ENSG00000213316	tier1	-	-	71	0	0.00	69	11	13.75	81	0	0.00	81	7	7.95
SGOL1	0	genome.wustl.edu	37	3	20216049	20216050	+	Frame_Shift_Ins	INS	-	-	T			TCGA-3B-A9HU-01A-11D-A38Z-09	TCGA-3B-A9HU-10A-01D-A38Z-09	-	-	-	T	-	-	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67fce992-e09f-4bde-b216-e9516a3bf796	74be41ea-729b-4b31-8c99-add92e25b393	3	20216049	20216050	-	T	INS	SGOL1	ENST00000263753	human	ensembl	74_37	-1	known	frame_shift_ins	c.974_973	p.M325fs	0.002:0.000	NULL	pfam_Shugoshin_N,pfam_Shugoshin_C	-	no_errors	SGOL1	HGNC	ENSG00000129810	tier1			22	0	0.00	20	3	13.04	105	1	0.94	132	4	2.94
ICAM5	0	genome.wustl.edu	37	19	10401797	10401797	+	Silent	SNP	C	C	T			TCGA-3B-A9HU-01A-11D-A38Z-09	TCGA-3B-A9HU-10A-01D-A38Z-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	67fce992-e09f-4bde-b216-e9516a3bf796	74be41ea-729b-4b31-8c99-add92e25b393	19	10401797	10401797	C	T	SNP	ICAM5	ENST00000221980	human	ensembl	74_37	+1	known	silent	c.132	p.F44	0.963	pfam_ICAM_N,prints_ICAM_VCAM_N	pfam_Ig_I-set,pfam_ICAM_N,smart_Ig_sub,smart_Ig_sub2,pfscan_Ig-like_dom,prints_ICAM_VCAM_N,prints_ICAM	-	no_errors	ICAM5	HGNC	ENSG00000105376	tier1	-	-	61	0	0.00	40	17	29.82	8	0	0.00	4	0	0.00
ENSG00000272913	0	genome.wustl.edu	37	2	96191372	96191372	+	R	DEL	A	A	-			TCGA-3B-A9HU-01A-11D-A38Z-09	TCGA-3B-A9HU-10A-01D-A38Z-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	67fce992-e09f-4bde-b216-e9516a3bf796	74be41ea-729b-4b31-8c99-add92e25b393	2	96191372	96191372	A	-	DEL	ENSG00000272913	ENST00000609975	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.546	-	-	-	no_errors	RP11-440D17.3	Clone_based_vega_gene	ENSG00000272913	tier1			48	0	0.00	31	14	31.11	2	0	0.00	0	0	0.00
LOC100507033	0	genome.wustl.edu	37	3	194219220	194219221	+	R	INS	-	-	TTTTG			TCGA-3B-A9HU-01A-11D-A38Z-09	TCGA-3B-A9HU-10A-01D-A38Z-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	67fce992-e09f-4bde-b216-e9516a3bf796	74be41ea-729b-4b31-8c99-add92e25b393	3	194219220	194219221	-	TTTTG	INS	LOC100507033	ENST00000455557	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000:0.000	-	-	-	no_errors	AC108676.1	Clone_based_vega_gene	ENSG00000244675	tier1			0	0	0.00	0	0	0.00	0	0	0.00	0	0	0.00
MUC12	0	genome.wustl.edu	37	7	100644303	100644303	+	Missense_Mutation	SNP	G	G	A			TCGA-3B-A9HU-01A-11D-A38Z-09	TCGA-3B-A9HU-10A-01D-A38Z-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	67fce992-e09f-4bde-b216-e9516a3bf796	74be41ea-729b-4b31-8c99-add92e25b393	7	100644303	100644303	G	A	SNP	MUC12	ENST00000536621	human	ensembl	74_37	+1	known	missense	c.10459	p.V3487I	0.001	NULL	pfam_SEA_dom	-	no_errors	MUC12	HGNC	ENSG00000205277	tier1	rs144363228	-	13	0	0.00	12	6	33.33	3	0	0.00	4	1	20.00
NRXN1	0	genome.wustl.edu	37	2	50147836	50147841	+	R	DEL	GTGTGT	GTGTGT	-			TCGA-3B-A9HU-01A-11D-A38Z-09	TCGA-3B-A9HU-10A-01D-A38Z-09	GTGTGT	GTGTGT					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	67fce992-e09f-4bde-b216-e9516a3bf796	74be41ea-729b-4b31-8c99-add92e25b393	2	50147836	50147841	GTGTGT	-	DEL	NRXN1	ENST00000484192	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000:0.001:0.005:0.106:0.113:0.127	-	-	-	no_errors	NRXN1	HGNC	ENSG00000179915	tier1			0	0	0.00	0	0	0.00	0	0	0.00	0	0	0.00
RGPD4	0	genome.wustl.edu	37	2	108459652	108459652	+	Missense_Mutation	SNP	G	G	C			TCGA-3B-A9HU-01A-11D-A38Z-09	TCGA-3B-A9HU-10A-01D-A38Z-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	67fce992-e09f-4bde-b216-e9516a3bf796	74be41ea-729b-4b31-8c99-add92e25b393	2	108459652	108459652	G	C	SNP	RGPD4	ENST00000354986	human	ensembl	74_37	+1	known	missense	c.593	p.R198P	0.811	NULL	pfam_Ran_bind_dom,pfam_GRIP,pfam_TPR_1,pfam_TPR_2,superfamily_GRIP,smart_TPR_repeat,smart_Ran_bind_dom,smart_GRIP,pfscan_GRIP,pfscan_TPR_repeat,pfscan_TPR-contain_dom,pfscan_Ran_bind_dom	-	no_errors	RGPD4	HGNC	ENSG00000196862	tier1	-	-	15	0	0.00	5	3	37.50	0	0	0.00	0	0	0.00
ZNF503	0	genome.wustl.edu	37	10	77161101	77161106	+	In_Frame_Del	DEL	CCGCCT	CCGCCT	-			TCGA-3B-A9HU-01A-11D-A38Z-09	TCGA-3B-A9HU-10A-01D-A38Z-09	CCGCCT	CCGCCT					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	67fce992-e09f-4bde-b216-e9516a3bf796	74be41ea-729b-4b31-8c99-add92e25b393	10	77161101	77161106	CCGCCT	-	DEL	ZNF503	ENST00000372524	human	ensembl	74_37	-1	known	in_frame_del	c.77_72	p.GG26in_frame_del	0.963:0.956:0.985:0.989:0.990:0.996	NULL	pfam_Tscrpt_rep_NocA-like,pfscan_Znf_C2H2	-	no_errors	ZNF503	HGNC	ENSG00000165655	tier1			0	0	0.00	1	0	0.00	0	0	0.00	1	0	0.00
TRIM58	0	genome.wustl.edu	37	1	248020718	248020718	+	Missense_Mutation	SNP	G	G	C			TCGA-3B-A9HU-01A-11D-A38Z-09	TCGA-3B-A9HU-10A-01D-A38Z-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	67fce992-e09f-4bde-b216-e9516a3bf796	74be41ea-729b-4b31-8c99-add92e25b393	1	248020718	248020718	G	C	SNP	TRIM58	ENST00000366481	human	ensembl	74_37	+1	known	missense	c.170	p.C57S	0.997	pfam_Znf_C3HC4_RING-type,smart_Znf_RING,pfscan_Znf_RING	pfam_SPRY_rcpt,pfam_Znf_B-box,pfam_Znf_C3HC4_RING-type,superfamily_ConA-like_lec_gl_sf,smart_Znf_RING,smart_Znf_B-box,smart_PRY,smart_SPla/RYanodine_receptor_subgr,pfscan_B30.2/SPRY,pfscan_Znf_B-box,pfscan_Znf_RING,prints_Butyrophylin	-	no_errors	TRIM58	HGNC	ENSG00000162722	tier1	-	-	55	0	0.00	32	13	28.89	2	0	0.00	3	4	57.14
ASAH1	0	genome.wustl.edu	37	8	17942299	17942299	+	Nonsense_Mutation	SNP	G	G	T			TCGA-3B-A9HU-01A-11D-A38Z-09	TCGA-3B-A9HU-10A-01D-A38Z-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	67fce992-e09f-4bde-b216-e9516a3bf796	74be41ea-729b-4b31-8c99-add92e25b393	8	17942299	17942299	G	T	SNP	ASAH1	ENST00000381733	human	ensembl	74_37	-1	known	nonsense	c.12	p.C4*	0.000	NULL	pfam_Chologlycine_hydro,pirsf_Acid_ceramidase-like	-	no_errors	ASAH1	HGNC	ENSG00000104763	tier1	-	-	38	0	0.00	49	5	9.26	77	0	0.00	91	2	2.13