Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	default_gene_name	gene_name_source	 ensembl_gene_id	tier	dbSNP	GMAF	n_ref_count	n_alt_count	normal_vaf	t_ref_count	t_alt_count	tumor_vaf	n_ref_count_val	n_alt_count_val	normal_vaf_val	t_ref_count_val	t_alt_count_val	tumor_vaf_val
CDHR1	0	genome.wustl.edu	37	10	85974228	85974228	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	10	85974228	85974228	G	A	SNP	CDHR1	ENST00000372117	human	ensembl	74_37	+1	known	missense	c.2431	p.V811M	0.997	NULL	pfam_Cadherin,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin,prints_Cadherin	-	no_errors	CDHR1	HGNC	ENSG00000148600	tier1	-	-	20	0	0.00	28	12	30.00	28	0	0.00	27	3	10.00
RNF213	0	genome.wustl.edu	37	17	78360610	78360610	+	Silent	SNP	C	C	T			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	17	78360610	78360610	C	T	SNP	RNF213	ENST00000582970	human	ensembl	74_37	+1	known	silent	c.14841	p.T4947	0.000	NULL	superfamily_P-loop_NTPase,smart_AAA+_ATPase,smart_Znf_RING,pfscan_Znf_RING	-	no_errors	RNF213	HGNC	ENSG00000173821	tier1	rs139685293	-	21	0	0.00	20	10	33.33	49	0	0.00	54	7	11.48
DH8	0	genome.wustl.edu	37	6	38705605	38705605	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	6	38705605	38705605	G	A	SNP	DH8	ENST00000359357	human	ensembl	74_37	+1	known	missense	c.322	p.G108R	1.000	NULL	pfam_Dynein_heavy_dom,pfam_Dynein_heavy_dom-1,pfam_Dynein_heavy_dom-2,pfam_ATPase_dyneun-rel_AAA,superfamily_P-loop_NTPase,smart_AAA+_ATPase	-	no_errors	DH8	HGNC	ENSG00000124721	tier1	-	-	57	0	0.00	50	12	19.35	55	0	0.00	33	9	21.43
MDN1	0	genome.wustl.edu	37	6	90450009	90450009	+	Missense_Mutation	SNP	T	T	C			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	6	90450009	90450009	T	C	SNP	MDN1	ENST00000369393	human	ensembl	74_37	-1	known	missense	c.4537	p.K1513E	0.992	pfam_ATPase_dyneun-rel_AAA,superfamily_P-loop_NTPase,smart_AAA+_ATPase,pirsf_Midasin	pfam_ATPase_dyneun-rel_AAA,pfam_ATPase_AAA-3,superfamily_P-loop_NTPase,superfamily_ARM-type_fold,smart_AAA+_ATPase,smart_VWF_A,pirsf_Midasin,pfscan_VWF_A	-	no_errors	MDN1	HGNC	ENSG00000112159	tier1	-	-	56	0	0.00	51	44	46.32	123	0	0.00	85	63	42.57
IGF2BP1	0	genome.wustl.edu	37	17	47115649	47115649	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	17	47115649	47115649	G	A	SNP	IGF2BP1	ENST00000290341	human	ensembl	74_37	+1	known	missense	c.521	p.R174Q	1.000	NULL	pfam_KH_dom_type_1,pfam_RRM_dom,smart_RRM_dom,smart_KH_dom,pfscan_KH_dom_type_1,pfscan_RRM_dom	-	no_errors	IGF2BP1	HGNC	ENSG00000159217	tier1	-	-	91	0	0.00	104	64	38.10	29	0	0.00	12	6	33.33
LRP1	0	genome.wustl.edu	37	12	57593005	57593005	+	Silent	SNP	G	G	A			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	12	57593005	57593005	G	A	SNP	LRP1	ENST00000243077	human	ensembl	74_37	+1	known	silent	c.9687	p.Q3229	0.999	pfam_LDLR_classB_rpt,superfamily_Growth_fac_rcpt_N_dom,smart_LDLR_classB_rpt,pfscan_LDLR_classB_rpt	pfam_LDrepeatLR_classA_rpt,pfam_LDLR_classB_rpt,superfamily_Growth_fac_rcpt_N_dom,superfamily_LDrepeatLR_classA_rpt,smart_LDrepeatLR_classA_rpt,smart_EGF-like_Ca-bd_dom,smart_EG-like_dom,smart_LDLR_classB_rpt,pfscan_EG-like_dom,pfscan_LDrepeatLR_classA_rpt,pfscan_LDLR_classB_rpt,prints_LDrepeatLR_classA_rpt	-	no_errors	LRP1	HGNC	ENSG00000123384	tier1	-	-	18	0	0.00	29	8	21.62	49	0	0.00	39	8	17.02
SELP	0	genome.wustl.edu	37	1	169572298	169572298	+	Silent	SNP	C	C	T			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	1	169572298	169572298	C	T	SNP	SELP	ENST00000263686	human	ensembl	74_37	-1	known	silent	c.1671	p.S557	0.323	pfam_Sushi_SCR_CCP,superfamily_Sushi_SCR_CCP,smart_Sushi_SCR_CCP,pfscan_Sushi_SCR_CCP	pfam_Sushi_SCR_CCP,pfam_C-type_lectin,superfamily_C-type_lectin_fold,superfamily_Sushi_SCR_CCP,smart_C-type_lectin,smart_Sushi_SCR_CCP,pfscan_EG-like_dom,pfscan_C-type_lectin,pfscan_Sushi_SCR_CCP,prints_Selectin_superfamily	-	no_errors	SELP	HGNC	ENSG00000174175	tier1	-	-	66	0	0.00	48	20	29.41	127	1	0.78	69	16	18.39
ELMOD1	0	genome.wustl.edu	37	11	107535878	107535878	+	Silent	SNP	G	G	A			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	11	107535878	107535878	G	A	SNP	ELMOD1	ENST00000265840	human	ensembl	74_37	+1	known	silent	c.960	p.A320	0.005	NULL	pfam_Engulfment_cell_motility_ELMO	-	no_errors	ELMOD1	HGNC	ENSG00000110675	tier1	-	-	53	0	0.00	11	9	45.00	106	0	0.00	13	24	64.86
MUC5B	0	genome.wustl.edu	37	11	1280228	1280228	+	Silent	SNP	G	G	T			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	11	1280228	1280228	G	T	SNP	MUC5B	ENST00000447027	human	ensembl	74_37	+1	known	silent	c.16659	p.G5553	0.000	pfam_VWF_C,smart_VWF_C,pfscan_VWF_C	pfam_VWF_type-D,pfam_Unchr_dom_Cys-rich,pfam_TIL_dom,pfam_VWF_C,superfamily_TIL_dom,smart_VWF_type-D,smart_Unchr_dom_Cys-rich,smart_VWC_out,smart_VWF_C,smart_Cys_knot_C,pfscan_Cys_knot_C,pfscan_VWF_C	-	no_errors	MUC5B	HGNC	ENSG00000117983	tier1	-	-	50	0	0.00	40	17	29.82	88	0	0.00	33	13	28.26
PXDNL	0	genome.wustl.edu	37	8	52287285	52287285	+	Silent	SNP	G	G	A			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	8	52287285	52287285	G	A	SNP	PXDNL	ENST00000356297	human	ensembl	74_37	-1	known	silent	c.3564	p.Y1188	0.001	pfam_Haem_peroxidase_animal,superfamily_Haem_peroxidase,prints_Haem_peroxidase_animal_subgr,pfscan_Haem_peroxidase_animal	pfam_Haem_peroxidase_animal,pfam_Ig_I-set,pfam_Immunoglobulin,pfam_Ig_V-set,pfam_VWF_C,pfam_Leu-rich_rpt,superfamily_Haem_peroxidase,smart_Leu-rich_rpt_typical-subtyp,smart_Cys-rich_flank_reg_C,smart_Ig_sub,smart_Ig_sub2,smart_VWF_C,prints_Haem_peroxidase_animal_subgr,pfscan_VWF_C,pfscan_Haem_peroxidase_animal,pfscan_Ig-like_dom	-	no_errors	PXDNL	HGNC	ENSG00000147485	tier1	-	-	51	0	0.00	18	35	66.04	82	0	0.00	37	40	51.95
AIPL1	0	genome.wustl.edu	37	17	6330048	6330048	+	Missense_Mutation	SNP	T	T	A			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	17	6330048	6330048	T	A	SNP	AIPL1	ENST00000381129	human	ensembl	74_37	-1	known	missense	c.671	p.K224M	1.000	NULL	pfam_PPIase_FKBP_dom,smart_TPR_repeat,pfscan_TPR-contain_dom	-	no_errors	AIPL1	HGNC	ENSG00000129221	tier1	-	-	30	0	0.00	32	22	40.74	30	0	0.00	22	13	37.14
PSMD7	0	genome.wustl.edu	37	16	74339214	74339214	+	Silent	SNP	T	T	A			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	16	74339214	74339214	T	A	SNP	PSMD7	ENST00000219313	human	ensembl	74_37	+1	known	silent	c.558	p.T186	0.985	NULL	pfam_JAB_MPN_dom,smart_JAB_MPN_dom	-	no_errors	PSMD7	HGNC	ENSG00000103035	tier1	-	-	24	0	0.00	26	24	48.00	97	0	0.00	62	39	38.61
ANXA4	0	genome.wustl.edu	37	2	70043324	70043324	+	Missense_Mutation	SNP	A	A	T			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	2	70043324	70043324	A	T	SNP	ANXA4	ENST00000394295	human	ensembl	74_37	+1	known	missense	c.626	p.H209L	1.000	pfam_Annexin_repeat,smart_Annexin_repeat,prints_AnnexinV	pfam_Annexin_repeat,smart_Annexin_repeat,prints_Annexin,prints_AnnexinIV,prints_AnnexinV	-	no_errors	ANXA4	HGNC	ENSG00000196975	tier1	-	-	61	0	0.00	41	16	28.07	152	0	0.00	60	36	37.50
LRP1	0	genome.wustl.edu	37	12	57594262	57594262	+	Nonsense_Mutation	SNP	G	G	A			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	12	57594262	57594262	G	A	SNP	LRP1	ENST00000243077	human	ensembl	74_37	+1	known	nonsense	c.10052	p.W3351*	1.000	pfam_LDrepeatLR_classA_rpt,superfamily_Growth_fac_rcpt_N_dom,smart_LDrepeatLR_classA_rpt,pfscan_LDrepeatLR_classA_rpt	pfam_LDrepeatLR_classA_rpt,pfam_LDLR_classB_rpt,superfamily_Growth_fac_rcpt_N_dom,superfamily_LDrepeatLR_classA_rpt,smart_LDrepeatLR_classA_rpt,smart_EGF-like_Ca-bd_dom,smart_EG-like_dom,smart_LDLR_classB_rpt,pfscan_EG-like_dom,pfscan_LDrepeatLR_classA_rpt,pfscan_LDLR_classB_rpt,prints_LDrepeatLR_classA_rpt	-	no_errors	LRP1	HGNC	ENSG00000123384	tier1	-	-	29	0	0.00	50	8	13.79	54	0	0.00	56	13	18.57
TIGD7	0	genome.wustl.edu	37	16	3349014	3349014	+	Missense_Mutation	SNP	T	T	C			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	16	3349014	3349014	T	C	SNP	TIGD7	ENST00000268674	human	ensembl	74_37	-1	known	missense	c.1601	p.N534S	0.996	NULL	pfam_DDE_SF_endonuclease_CENPB-like,pfam_HTH_CenpB_D-bd_dom,pfam_HTH_Psq,superfamily_Homeodomain-like,smart_HTH_CenpB_D-bd_dom,pfscan_HTH_Psq	-	no_errors	TIGD7	HGNC	ENSG00000140993	tier1	-	-	92	0	0.00	74	60	44.78	167	0	0.00	79	53	40.15
ENSG00000257395	0	genome.wustl.edu	37	14	20151749	20151749	+	R	SNP	T	T	A			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	14	20151749	20151749	T	A	SNP	ENSG00000257395	ENST00000547175	human	ensembl	74_37	+1	known	rna	NULL	NULL	1.000	-	-	-	no_errors	RP11-597A11.2	Clone_based_vega_gene	ENSG00000257395	tier1	-	-	21	0	0.00	9	3	25.00	15	0	0.00	12	2	14.29
CHGB	0	genome.wustl.edu	37	20	5904558	5904558	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	20	5904558	5904558	G	A	SNP	CHGB	ENST00000378961	human	ensembl	74_37	+1	known	missense	c.1768	p.A590T	0.000	pfam_Granin	pfam_Granin,prints_Chromogranin_AB	-	no_errors	CHGB	HGNC	ENSG00000089199	tier1	rs148235020	-	73	0	0.00	39	46	54.12	66	0	0.00	40	27	39.71
HAO1	0	genome.wustl.edu	37	20	7894822	7894822	+	Silent	SNP	C	C	T			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	20	7894822	7894822	C	T	SNP	HAO1	ENST00000378789	human	ensembl	74_37	-1	known	silent	c.534	p.P178	0.926	pfam_FMN-dep_DH,pirsf_Alpha-hydoxy_acid_DH_FMN	pfam_FMN-dep_DH,pfam_Glu_synth_centr_C,pirsf_Alpha-hydoxy_acid_DH_FMN	-	no_errors	HAO1	HGNC	ENSG00000101323	tier1	-	-	47	0	0.00	21	25	54.35	143	0	0.00	50	71	58.20
HUWE1	0	genome.wustl.edu	37	X	53631666	53631666	+	Missense_Mutation	SNP	A	A	G			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	X	53631666	53631666	A	G	SNP	HUWE1	ENST00000262854	human	ensembl	74_37	-1	known	missense	c.2626	p.C876R	0.989	NULL	pfam_E3_Ub_ligase_DUF913,pfam_HECT,pfam_E3_Ub_ligase_DUF908,pfam_WWE-dom,pfam_UBA/Ts_N,superfamily_HECT,superfamily_UBA-like,superfamily_ARM-type_fold,smart_UBA/transl_elong_EF1B_N_euk,smart_HECT,pfscan_HECT,pfscan_UBA/transl_elong_EF1B_N_euk,pfscan_WWE-dom	-	no_errors	HUWE1	HGNC	ENSG00000086758	tier1	-	-	23	0	0.00	47	41	46.59	27	0	0.00	67	35	33.98
DGKK	0	genome.wustl.edu	37	X	50114724	50114724	+	R	SNP	T	T	C			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	X	50114724	50114724	T	C	SNP	DGKK	ENST00000376025	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.998	-	-	-	no_errors	DGKK	HGNC	ENSG00000204466	tier1	-	-	32	0	0.00	39	12	23.53	72	1	1.37	114	19	14.29
USP10	0	genome.wustl.edu	37	16	84801916	84801916	+	Missense_Mutation	SNP	G	G	C			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	16	84801916	84801916	G	C	SNP	USP10	ENST00000570191	human	ensembl	74_37	+1	known	missense	c.1962	p.L654F	1.000	pfam_Peptidase_C19/C67,pfscan_Peptidase_C19/C67	pfam_Peptidase_C19/C67,pfam_Ataxin-2_C,pfscan_Peptidase_C19/C67	-	no_errors	USP10	HGNC	ENSG00000103194	tier1	-	-	27	0	0.00	31	8	20.51	74	1	1.33	47	18	27.69
WIZ	0	genome.wustl.edu	37	19	15547866	15547866	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	19	15547866	15547866	C	T	SNP	WIZ	ENST00000389282	human	ensembl	74_37	-1	known	missense	c.2347	p.G783S	0.999	smart_Znf_C2H2-like,pfscan_Znf_C2H2	smart_Znf_C2H2-like,pfscan_Znf_C2H2	-	no_errors	WIZ	HGNC	ENSG00000011451	tier1	-	-	58	0	0.00	44	60	57.69	51	0	0.00	17	39	69.64
KIF19	0	genome.wustl.edu	37	17	72340475	72340475	+	Missense_Mutation	SNP	C	C	G			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	17	72340475	72340475	C	G	SNP	KIF19	ENST00000389916	human	ensembl	74_37	+1	known	missense	c.570	p.I190M	1.000	pfam_Kinesin_motor_dom,superfamily_P-loop_NTPase,smart_Kinesin_motor_dom,pfscan_Kinesin_motor_dom	pfam_Kinesin_motor_dom,superfamily_P-loop_NTPase,smart_Kinesin_motor_dom,prints_Kinesin_motor_dom,pfscan_Kinesin_motor_dom	-	no_errors	KIF19	HGNC	ENSG00000196169	tier1	-	-	10	0	0.00	11	8	42.11	34	0	0.00	17	20	54.05
GABRA1	0	genome.wustl.edu	37	5	161309663	161309663	+	Missense_Mutation	SNP	T	T	C			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	5	161309663	161309663	T	C	SNP	GABRA1	ENST00000023897	human	ensembl	74_37	+1	known	missense	c.659	p.L220P	1.000	pfam_Neur_chan_lig-bd,superfamily_Neur_chan_lig-bd,prints_GABAAa_rcpt,tigrfam_Neur_channel	pfam_Neur_chan_lig-bd,pfam_Neurotrans-gated_channel_TM,superfamily_Neur_chan_lig-bd,superfamily_Neurotrans-gated_channel_TM,prints_GABAAa_rcpt,prints_GABAA_rcpt,prints_GABBAa1_rcpt,prints_Neur_channel,prints_GABBAg_rcpt,tigrfam_Neur_channel	-	no_errors	GABRA1	HGNC	ENSG00000022355	tier1	-	-	55	0	0.00	50	8	13.79	194	0	0.00	109	28	20.44
ATP7B	0	genome.wustl.edu	37	13	52536007	52536007	+	Missense_Mutation	SNP	C	C	A			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	13	52536007	52536007	C	A	SNP	ATP7B	ENST00000242839	human	ensembl	74_37	-1	known	missense	c.1912	p.A638S	0.995	superfamily_HeavyMe-assoc_HMA	pfam_HeavyMe-assoc_HMA,pfam_ATPase_P-typ_transduc_dom_A,pfam_HAD-like_dom,superfamily_HAD-like_dom,superfamily_HeavyMe-assoc_HMA,pfscan_HeavyMe-assoc_HMA,prints_Cation_transp_P_typ_ATPase,tigrfam_Cation_transp_P-typ_ATPase_IB,tigrfam_Cation_transp_P_typ_ATPase,tigrfam_HMA_Cu_ion-bd	-	no_errors	ATP7B	HGNC	ENSG00000123191	tier1	-	-	69	0	0.00	93	26	21.85	124	0	0.00	97	25	20.33
IL12RB1	0	genome.wustl.edu	37	19	18179264	18179264	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	19	18179264	18179264	G	A	SNP	IL12RB1	ENST00000593993	human	ensembl	74_37	-1	known	missense	c.1262	p.S421F	0.646	NULL	pfam_Fibronectin_type3,superfamily_Fibronectin_type3,smart_Fibronectin_type3,pfscan_Fibronectin_type3	-	no_errors	IL12RB1	HGNC	ENSG00000096996	tier1	rs201548803	-	45	0	0.00	98	47	32.41	70	0	0.00	134	29	17.79
CTN2	0	genome.wustl.edu	37	2	80085281	80085281	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	2	80085281	80085281	G	A	SNP	CTN2	ENST00000361291	human	ensembl	74_37	+1	known	missense	c.543	p.M181I	1.000	pfam_Vinculin/catenin,superfamily_Vinculin/catenin	pfam_Vinculin/catenin,superfamily_Vinculin/catenin,prints_Alpha_catenin,prints_Vinculin	-	no_errors	CTN2	HGNC	ENSG00000066032	tier1	-	-	23	0	0.00	25	11	30.56	80	0	0.00	39	12	23.53
CNTN2	0	genome.wustl.edu	37	1	205028265	205028265	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	1	205028265	205028265	G	A	SNP	CNTN2	ENST00000331830	human	ensembl	74_37	+1	known	missense	c.541	p.G181R	0.980	smart_Ig_sub,pfscan_Ig-like_dom	pfam_Ig_I-set,pfam_Fibronectin_type3,pfam_Immunoglobulin,pfam_Ig_V-set,superfamily_Fibronectin_type3,smart_Ig_sub,smart_Ig_sub2,smart_Fibronectin_type3,pfscan_Fibronectin_type3,pfscan_Ig-like_dom	-	no_errors	CNTN2	HGNC	ENSG00000184144	tier1	-	-	32	0	0.00	17	10	37.04	106	0	0.00	42	17	28.81
UBXN8	0	genome.wustl.edu	37	8	30601706	30601706	+	R	SNP	C	C	T			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	8	30601706	30601706	C	T	SNP	UBXN8	ENST00000265616	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.193	-	-	-	no_errors	UBXN8	HGNC	ENSG00000104691	tier1	-	-	37	0	0.00	27	15	35.71	48	0	0.00	36	29	43.94
MYT1L	0	genome.wustl.edu	37	2	1947065	1947065	+	Missense_Mutation	SNP	T	T	A			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	2	1947065	1947065	T	A	SNP	MYT1L	ENST00000399161	human	ensembl	74_37	-1	known	missense	c.194	p.D65V	1.000	NULL	pfam_Myelin_TF,pfam_Znf_C2HC	-	no_errors	MYT1L	HGNC	ENSG00000186487	tier1	-	-	42	0	0.00	10	18	64.29	59	0	0.00	11	13	54.17
LOC149134	0	genome.wustl.edu	37	1	246954051	246954051	+	R	SNP	C	C	A			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	1	246954051	246954051	C	A	SNP	LOC149134	ENST00000419361	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.999	-	-	-	no_errors	RP11-439E19.3	Clone_based_vega_gene	ENSG00000227953	tier1	-	-	48	0	0.00	51	19	27.14	170	0	0.00	114	39	25.49
USP25	0	genome.wustl.edu	37	21	17183456	17183456	+	Silent	SNP	G	G	T			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	21	17183456	17183456	G	T	SNP	USP25	ENST00000400183	human	ensembl	74_37	+1	known	silent	c.858	p.T286	1.000	pfam_Peptidase_C19/C67,pfscan_Peptidase_C19/C67	pfam_Peptidase_C19/C67,pfam_Ubiquitin-int_motif,superfamily_UBA-like,smart_Ubiquitin-int_motif,pfscan_Ubiquitin-int_motif,pfscan_Peptidase_C19/C67	-	no_errors	USP25	HGNC	ENSG00000155313	tier1	-	-	111	0	0.00	83	24	22.43	116	0	0.00	78	14	15.22
ENSG00000180458	0	genome.wustl.edu	37	19	38039815	38039815	+	R	SNP	C	C	T			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	19	38039815	38039815	C	T	SNP	ENSG00000180458	ENST00000316807	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.006	-	-	-	no_errors	CTD-3064H18.4	Clone_based_vega_gene	ENSG00000180458	tier1	-	-	98	0	0.00	106	36	25.35	11	0	0.00	13	5	27.78
PKP2	0	genome.wustl.edu	37	12	32977078	32977078	+	Silent	SNP	G	G	A			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	12	32977078	32977078	G	A	SNP	PKP2	ENST00000070846	human	ensembl	74_37	-1	known	silent	c.1707	p.G569	0.996	superfamily_ARM-type_fold	pfam_Armadillo,superfamily_ARM-type_fold,smart_Armadillo,pfscan_Armadillo	-	no_errors	PKP2	HGNC	ENSG00000057294	tier1	-	-	37	0	0.00	23	7	23.33	51	0	0.00	22	8	26.67
FCGR3A	0	genome.wustl.edu	37	1	161512900	161512900	+	Missense_Mutation	SNP	T	T	C			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	1	161512900	161512900	T	C	SNP	FCGR3A	ENST00000367969	human	ensembl	74_37	-1	known	missense	c.775	p.T259A	0.997	NULL	smart_Ig_sub,pfscan_Ig-like_dom	-	no_errors	FCGR3A	HGNC	ENSG00000203747	tier1	-	-	84	0	0.00	71	27	27.55	89	0	0.00	60	24	28.57
SEZ6L	0	genome.wustl.edu	37	22	26688873	26688873	+	Missense_Mutation	SNP	C	C	A			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	22	26688873	26688873	C	A	SNP	SEZ6L	ENST00000248933	human	ensembl	74_37	+1	known	missense	c.596	p.P199H	0.930	NULL	pfam_CUB_dom,pfam_Sushi_SCR_CCP,superfamily_CUB_dom,superfamily_Sushi_SCR_CCP,smart_CUB_dom,smart_Sushi_SCR_CCP,pfscan_CUB_dom,pfscan_Sushi_SCR_CCP	-	no_errors	SEZ6L	HGNC	ENSG00000100095	tier1	-	-	31	0	0.00	25	13	34.21	87	0	0.00	71	22	23.66
TTN	0	genome.wustl.edu	37	2	179470001	179470001	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	2	179470001	179470001	C	T	SNP	TTN	ENST00000342992	human	ensembl	74_37	-1	known	missense	c.46199	p.R15400H	1.000	superfamily_Calpain_domain_III,superfamily_RNaseH-like_dom,pfscan_Ig-like_dom	pfam_Ig_I-set,pfam_Fibronectin_type3,pfam_Immunoglobulin,pfam_Ig_V-set,pfam_Titin_Z,pfam_PPAK_motif,pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,superfamily_Fibronectin_type3,superfamily_Calpain_domain_III,superfamily_RNaseH-like_dom,smart_Ig_sub,smart_Ig_sub2,smart_Ig_V-set_subgr,smart_Fibronectin_type3,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Fibronectin_type3,pfscan_Prot_kinase_dom,pfscan_Ig-like_dom	-	no_errors	TTN	HGNC	ENSG00000155657	tier1	rs200100660	-	63	0	0.00	30	24	43.64	73	0	0.00	34	18	34.62
ATP6V0A4	0	genome.wustl.edu	37	7	138429926	138429926	+	Silent	SNP	A	A	G			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	7	138429926	138429926	A	G	SNP	ATP6V0A4	ENST00000310018	human	ensembl	74_37	-1	known	silent	c.1420	p.L474	0.009	pfam_V-ATPase_116kDa_su	pfam_V-ATPase_116kDa_su	-	no_errors	ATP6V0A4	HGNC	ENSG00000105929	tier1	-	-	45	0	0.00	39	33	45.21	110	0	0.00	68	52	43.33
USH2A	0	genome.wustl.edu	37	1	216256823	216256823	+	Missense_Mutation	SNP	T	T	A			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	1	216256823	216256823	T	A	SNP	USH2A	ENST00000366943	human	ensembl	74_37	-1	known	missense	c.5273	p.N1758I	0.994	pfam_Laminin_G,superfamily_ConA-like_lec_gl_sf,superfamily_Fibronectin_type3,smart_Laminin_G,pfscan_Laminin_G	pfam_Fibronectin_type3,pfam_EGF_laminin,pfam_Laminin_G,superfamily_ConA-like_lec_gl_sf,superfamily_Fibronectin_type3,smart_LamG-like,smart_Laminin_N,smart_EGF_laminin,smart_Fibronectin_type3,smart_Laminin_G,pfscan_EGF_laminin,pfscan_Fibronectin_type3,pfscan_Laminin_G,pfscan_Laminin_N	-	no_errors	USH2A	HGNC	ENSG00000042781	tier1	-	-	140	0	0.00	55	33	37.50	171	0	0.00	30	20	40.00
ZSCAN31	0	genome.wustl.edu	37	6	28297405	28297405	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	6	28297405	28297405	G	A	SNP	ZSCAN31	ENST00000344279	human	ensembl	74_37	-1	known	missense	c.56	p.P19L	0.000	NULL	pfam_Tscrpt_reg_SCAN,pfam_Znf_C2H2,superfamily_Retrov_capsid_C,smart_Tscrpt_reg_SCAN,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Tscrpt_reg_SCAN	-	no_errors	ZSCAN31	HGNC	ENSG00000235109	tier1	-	-	62	0	0.00	35	21	37.50	161	0	0.00	61	27	30.68
OR1A1	0	genome.wustl.edu	37	17	3119374	3119374	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	17	3119374	3119374	G	A	SNP	OR1A1	ENST00000304094	human	ensembl	74_37	+1	known	missense	c.460	p.A154T	0.000	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR1A1	HGNC	ENSG00000172146	tier1	-	-	27	0	0.00	24	20	45.45	60	0	0.00	36	14	28.00
PLAGL2	0	genome.wustl.edu	37	20	30784433	30784433	+	Missense_Mutation	SNP	A	A	T			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	20	30784433	30784433	A	T	SNP	PLAGL2	ENST00000246229	human	ensembl	74_37	-1	known	missense	c.1313	p.V438D	1.000	NULL	pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2	-	no_errors	PLAGL2	HGNC	ENSG00000126003	tier1	-	-	35	0	0.00	51	12	19.05	68	0	0.00	68	11	13.92
ADAMDEC1	0	genome.wustl.edu	37	8	24254877	24254877	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	8	24254877	24254877	G	A	SNP	ADAMDEC1	ENST00000256412	human	ensembl	74_37	+1	known	missense	c.535	p.E179K	0.073	NULL	pfam_Peptidase_M12B,pfam_Peptidase_M12B_N,pfam_Blood-coag_inhib_Disintegrin,superfamily_Blood-coag_inhib_Disintegrin,smart_Blood-coag_inhib_Disintegrin,pfscan_Blood-coag_inhib_Disintegrin,pfscan_Peptidase_M12B	-	no_errors	ADAMDEC1	HGNC	ENSG00000134028	tier1	-	-	49	0	0.00	37	8	17.78	136	0	0.00	74	27	26.73
SPTB	0	genome.wustl.edu	37	14	65220346	65220346	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	14	65220346	65220346	C	T	SNP	SPTB	ENST00000389722	human	ensembl	74_37	-1	known	missense	c.6511	p.A2171T	0.997	pirsf_Spectrin_bsu,smart_Spectrin/alpha-actinin	pirsf_Spectrin_bsu,pfam_Spectrin_repeat,pfam_CH-domain,pfam_CAMSAP_CH,pfam_Pleckstrin_homology,superfamily_CH-domain,smart_CH-domain,smart_Spectrin/alpha-actinin,smart_Pleckstrin_homology,prints_PH_dom-spectrin-type,pfscan_CH-domain,pfscan_Pleckstrin_homology	-	no_errors	SPTB	HGNC	ENSG00000070182	tier1	-	-	26	0	0.00	13	8	38.10	34	0	0.00	22	17	43.59
ZNF280A	0	genome.wustl.edu	37	22	22869380	22869380	+	Missense_Mutation	SNP	G	G	T			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	22	22869380	22869380	G	T	SNP	ZNF280A	ENST00000302097	human	ensembl	74_37	-1	known	missense	c.575	p.S192Y	0.001	NULL	smart_Znf_C2H2-like,pfscan_Znf_C2H2	-	no_errors	ZNF280A	HGNC	ENSG00000169548	tier1	-	-	21	0	0.00	35	7	16.67	162	0	0.00	77	34	30.63
PRAMEF22	0	genome.wustl.edu	37	1	13036643	13036643	+	Missense_Mutation	SNP	C	C	G			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	1	13036643	13036643	C	G	SNP	PRAMEF22	ENST00000376187	human	ensembl	74_37	+1	known	missense	c.715	p.L239V	0.014	NULL	NULL	-	no_errors	PRAMEF22	HGNC	ENSG00000204508	tier1	-	-	253	0	0.00	257	104	28.81	132	0	0.00	99	52	34.44
PNPLA7	0	genome.wustl.edu	37	9	140395146	140395146	+	Missense_Mutation	SNP	T	T	C			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	9	140395146	140395146	T	C	SNP	PNPLA7	ENST00000406427	human	ensembl	74_37	-1	known	missense	c.1754	p.Y585C	1.000	pfam_cNMP-bd_dom,superfamily_cNMP-bd-like,smart_cNMP-bd_dom,pfscan_cNMP-bd_dom	pfam_cNMP-bd_dom,pfam_Patatin/PLipase_A2-rel,superfamily_Acyl_Trfase/lysoPLipase,superfamily_cNMP-bd-like,smart_cNMP-bd_dom,pfscan_cNMP-bd_dom	-	no_errors	PNPLA7	HGNC	ENSG00000130653	tier1	-	-	54	0	0.00	82	25	23.36	46	0	0.00	31	6	16.22
ZFR2	0	genome.wustl.edu	37	19	3806098	3806098	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	19	3806098	3806098	C	T	SNP	ZFR2	ENST00000262961	human	ensembl	74_37	-1	known	missense	c.2669	p.R890Q	1.000	pfam_DZF,smart_DZF	pfam_DZF,smart_Znf_U1,smart_Znf_C2H2-like,smart_DZF	-	no_errors	ZFR2	HGNC	ENSG00000105278	tier1	-	-	8	0	0.00	27	7	20.59	11	0	0.00	10	3	23.08
KLK12	0	genome.wustl.edu	37	19	51537872	51537872	+	Silent	SNP	C	C	T			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	19	51537872	51537872	C	T	SNP	KLK12	ENST00000250351	human	ensembl	74_37	-1	known	silent	c.6	p.G2	0.000	NULL	pfam_Peptidase_S1,superfamily_Trypsin-like_Pept_dom,smart_Peptidase_S1,pfscan_Peptidase_S1,prints_Peptidase_S1A	-	no_errors	KLK12	HGNC	ENSG00000186474	tier1	-	-	52	0	0.00	38	13	25.49	124	0	0.00	47	23	32.86
ALG6	0	genome.wustl.edu	37	1	63879619	63879619	+	R	SNP	G	G	A			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	1	63879619	63879619	G	A	SNP	ALG6	ENST00000465969	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.003	-	-	-	no_errors	ALG6	HGNC	ENSG00000088035	tier1	-	-	65	0	0.00	45	16	26.23	101	0	0.00	48	23	32.39
CDHR2	0	genome.wustl.edu	37	5	176002819	176002819	+	Missense_Mutation	SNP	G	G	C			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	5	176002819	176002819	G	C	SNP	CDHR2	ENST00000261944	human	ensembl	74_37	+1	known	missense	c.939	p.E313D	0.999	pfam_Cadherin,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin	pfam_Cadherin,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin,prints_Cadherin	-	no_errors	CDHR2	HGNC	ENSG00000074276	tier1	-	-	48	0	0.00	69	11	13.75	32	0	0.00	58	13	18.31
RHOBTB1	0	genome.wustl.edu	37	10	62648024	62648024	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	10	62648024	62648024	G	A	SNP	RHOBTB1	ENST00000337910	human	ensembl	74_37	-1	known	missense	c.1402	p.H468Y	1.000	superfamily_BTB/POZ_fold	pfam_BTB_POZ,pfam_Small_GTPase,pfam_MIRO-like,superfamily_P-loop_NTPase,superfamily_BTB/POZ_fold,smart_Small_GTPase_Ras,smart_Small_GTPase_Rab_type,smart_Small_GTPase_Rho,smart_BTB/POZ-like,pfscan_BTB/POZ-like,prints_Small_GTPase	-	no_errors	RHOBTB1	HGNC	ENSG00000072422	tier1	-	-	33	0	0.00	56	7	11.11	120	0	0.00	100	13	11.40
THBS4	0	genome.wustl.edu	37	5	79351744	79351744	+	Silent	SNP	C	C	G			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	5	79351744	79351744	C	G	SNP	THBS4	ENST00000350881	human	ensembl	74_37	+1	known	silent	c.429	p.L143	1.000	superfamily_ConA-like_lec_gl_sf,smart_Laminin_G	pfam_Thrombospondin_C,pfam_Thbs/COMP_coiled-coil,pfam_Thrombospondin_3-like_rpt,pfam_EGF-like_Ca-bd_dom,superfamily_ConA-like_lec_gl_sf,smart_Laminin_G,smart_EG-like_dom,smart_EGF-like_Ca-bd_dom,pfscan_EG-like_dom	-	no_errors	THBS4	HGNC	ENSG00000113296	tier1	-	-	34	0	0.00	17	13	43.33	112	0	0.00	72	47	39.50
CAPN12	0	genome.wustl.edu	37	19	39229227	39229227	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	19	39229227	39229227	G	A	SNP	CAPN12	ENST00000328867	human	ensembl	74_37	-1	known	missense	c.791	p.T264M	1.000	pfam_Peptidase_C2_calpain_cat,smart_Peptidase_C2_calpain_cat,pfscan_Peptidase_C2_calpain_cat	pfam_Peptidase_C2_calpain_cat,pfam_Calpain_domain_III,superfamily_Calpain_domain_III,smart_Peptidase_C2_calpain_cat,smart_Calpain_III,pfscan_EF_hand_dom,pfscan_Peptidase_C2_calpain_cat,prints_Calpain_cysteine_protease	-	no_errors	CAPN12	HGNC	ENSG00000182472	tier1	-	-	38	0	0.00	60	15	20.00	77	0	0.00	87	31	26.27
TFR2	0	genome.wustl.edu	37	7	100218565	100218565	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	7	100218565	100218565	C	T	SNP	TFR2	ENST00000223051	human	ensembl	74_37	-1	known	missense	c.2321	p.R774H	1.000	pfam_TFR-like_dimer_dom,superfamily_TFR-like_dimer_dom	pfam_TFR-like_dimer_dom,pfam_Peptidase_M28,pfam_Protease-assoc_domain,superfamily_TFR-like_dimer_dom	-	no_errors	TFR2	HGNC	ENSG00000106327	tier1	-	-	47	0	0.00	39	8	17.02	34	0	0.00	23	6	20.69
CASP8AP2	0	genome.wustl.edu	37	6	90583756	90583756	+	R	SNP	T	T	A			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	6	90583756	90583756	T	A	SNP	CASP8AP2	ENST00000237177	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.902	-	-	-	no_errors	CASP8AP2	HGNC	ENSG00000118412	tier1	-	-	41	0	0.00	54	16	22.86	49	0	0.00	30	9	22.50
LRP1	0	genome.wustl.edu	37	12	57595284	57595284	+	Silent	SNP	G	G	A			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	12	57595284	57595284	G	A	SNP	LRP1	ENST00000243077	human	ensembl	74_37	+1	known	silent	c.10350	p.E3450	0.997	superfamily_LDrepeatLR_classA_rpt,smart_LDrepeatLR_classA_rpt	pfam_LDrepeatLR_classA_rpt,pfam_LDLR_classB_rpt,superfamily_Growth_fac_rcpt_N_dom,superfamily_LDrepeatLR_classA_rpt,smart_LDrepeatLR_classA_rpt,smart_EGF-like_Ca-bd_dom,smart_EG-like_dom,smart_LDLR_classB_rpt,pfscan_EG-like_dom,pfscan_LDrepeatLR_classA_rpt,pfscan_LDLR_classB_rpt,prints_LDrepeatLR_classA_rpt	-	no_errors	LRP1	HGNC	ENSG00000123384	tier1	-	-	47	0	0.00	44	23	34.33	99	0	0.00	104	30	22.22
CTNND2	0	genome.wustl.edu	37	5	10973629	10973629	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	5	10973629	10973629	C	T	SNP	CTNND2	ENST00000304623	human	ensembl	74_37	-1	known	missense	c.3614	p.R1205H	1.000	NULL	pfam_Armadillo,superfamily_ARM-type_fold,smart_Armadillo,pfscan_Armadillo	-	no_errors	CTNND2	HGNC	ENSG00000169862	tier1	-	-	27	0	0.00	27	9	25.00	162	0	0.00	83	65	43.92
VPS13A	0	genome.wustl.edu	37	9	79897094	79897094	+	Missense_Mutation	SNP	A	A	C			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	A	A	A	C	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	9	79897094	79897094	A	C	SNP	VPS13A	ENST00000360280	human	ensembl	74_37	+1	known	missense	c.3022	p.N1008H	1.000	NULL	pfam_VPSAP_dom,pfam_Autophagy-rel_C	-	no_errors	VPS13A	HGNC	ENSG00000197969	tier1	-	-	86	0	0.00	69	24	25.81	81	0	0.00	43	13	23.21
RB1	0	genome.wustl.edu	37	13	48947546	48947546	+	Frame_Shift_Del	DEL	T	T	-			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	T	T	T	-	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	13	48947546	48947546	T	-	DEL	RB1	ENST00000267163	human	ensembl	74_37	+1	known	frame_shift_del	c.1133	p.M379fs	1.000	pfam_RB_A	pfam_RB_C,pfam_RB_A,pfam_RB_B,pfam_RB_N,superfamily_Cyclin-like,smart_Cyclin-like	-	no_errors	RB1	HGNC	ENSG00000139687	tier1			36	0	0.00	29	27	48.21	100	0	0.00	32	24	42.86
ATRX	0	genome.wustl.edu	37	X	76938366	76938367	+	Frame_Shift_Ins	INS	-	-	T			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	-	-	-	T	-	-	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	X	76938366	76938367	-	T	INS	ATRX	ENST00000373344	human	ensembl	74_37	-1	known	frame_shift_ins	c.2382_2381	p.K796fs	0.987:0.998	NULL	pfam_SNF2_N,pfam_Helicase_C,superfamily_P-loop_NTPase,superfamily_Znf_FYVE_PHD,smart_Helicase_ATP-bd,smart_Helicase_C,pfscan_Helicase_ATP-bd,pfscan_Helicase_C	-	no_errors	ATRX	HGNC	ENSG00000085224	tier1			42	0	0.00	16	34	68.00	54	0	0.00	11	22	66.67
SMCR5	0	genome.wustl.edu	37	17	17682105	17682106	+	R	DEL	TG	TG	-			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	TG	TG	TG	-	TG	TG	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	17	17682105	17682106	TG	-	DEL	SMCR5	ENST00000543475	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.018:0.381	-	-	-	no_errors	SMCR5	HGNC	ENSG00000226746	tier1			23	0	0.00	28	21	42.86	125	0	0.00	54	46	46.00
ALOX5	0	genome.wustl.edu	37	10	45939709	45939709	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	10	45939709	45939709	C	T	SNP	ALOX5	ENST00000374391	human	ensembl	74_37	+1	known	missense	c.1820	p.A607V	1.000	pfam_LipOase_C,superfamily_LipOase_C,prints_LipOase_mml	pfam_LipOase_C,pfam_PLAT/LH2_dom,superfamily_LipOase_C,superfamily_Lipase_LipOase,smart_PLAT/LH2_dom,prints_LipOase_mml,prints_LipOase_C,pfscan_PLAT/LH2_dom	-	no_errors	ALOX5	HGNC	ENSG00000012779	tier1	-	-	99	0	0.00	25	86	77.48	18	0	0.00	0	7	100.00
ENSG00000221317	0	genome.wustl.edu	37	X	121605625	121605625	+	R	SNP	T	T	A			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	X	121605625	121605625	T	A	SNP	ENSG00000221317	ENST00000408390	human	ensembl	74_37	-1	novel	rna	NULL	NULL	0.030	-	-	-	no_errors	AL513487.1	Clone_based_ensembl_gene	ENSG00000221317	tier1	-	-	21	0	0.00	5	31	86.11	24	0	0.00	0	16	100.00
ZNF732	0	genome.wustl.edu	37	4	265951	265951	+	Missense_Mutation	SNP	A	A	C			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	A	A	A	C	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	4	265951	265951	A	C	SNP	ZNF732	ENST00000419098	human	ensembl	74_37	-1	known	missense	c.695	p.F232C	0.264	smart_Znf_C2H2-like,pfscan_Znf_C2H2	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF732	HGNC	ENSG00000186777	tier1	-	-	28	0	0.00	28	25	47.17	22	0	0.00	8	5	38.46
LILRB4	0	genome.wustl.edu	37	19	55179188	55179188	+	Nonsense_Mutation	SNP	G	G	T			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	19	55179188	55179188	G	T	SNP	LILRB4	ENST00000270452	human	ensembl	74_37	+1	known	nonsense	c.1144	p.E382*	0.008	NULL	pfam_Immunoglobulin,pfscan_Ig-like_dom	-	no_errors	LILRB4	HGNC	ENSG00000186818	tier1	-	-	79	0	0.00	90	12	11.76	52	0	0.00	67	7	9.21
APPBP2	0	genome.wustl.edu	37	17	58529372	58529372	+	Missense_Mutation	SNP	A	A	T			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	17	58529372	58529372	A	T	SNP	APPBP2	ENST00000083182	human	ensembl	74_37	-1	known	missense	c.1373	p.I458N	1.000	smart_TPR_repeat,pfscan_TPR_repeat,pfscan_TPR-contain_dom	smart_TPR_repeat,pfscan_TPR_repeat,pfscan_TPR-contain_dom	-	no_errors	APPBP2	HGNC	ENSG00000062725	tier1	-	-	67	0	0.00	60	13	17.81	104	0	0.00	90	5	5.26
PITPNM2	0	genome.wustl.edu	37	12	123485013	123485013	+	Missense_Mutation	SNP	T	T	A			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	12	123485013	123485013	T	A	SNP	PITPNM2	ENST00000546049	human	ensembl	74_37	-1	putative	missense	c.1351	p.I451F	0.295	NULL	pfam_PI_transfer,prints_PI_transfer	-	no_errors	PITPNM2	HGNC	ENSG00000090975	tier1	-	-	35	0	0.00	22	6	21.43	75	0	0.00	50	5	9.09
ENSG00000215933	0	genome.wustl.edu	37	X	71372204	71372213	+	R	DEL	CGCGCACACA	CGCGCACACA	-			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	CGCGCACACA	CGCGCACACA					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	X	71372204	71372213	CGCGCACACA	-	DEL	ENSG00000215933	ENST00000401114	human	ensembl	74_37	-1	novel	rna	NULL	NULL	0.000:0.000:0.000:0.001:0.015:0.009:0.008:0.004:0.003:0.003	-	-	-	no_errors	BX119917.1	Clone_based_ensembl_gene	ENSG00000215933	tier1			6	0	0.00	6	0	0.00	6	0	0.00	6	0	0.00
HMGB2	0	genome.wustl.edu	37	4	174253279	174253279	+	Silent	SNP	C	C	T			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	4	174253279	174253279	C	T	SNP	HMGB2	ENST00000296503	human	ensembl	74_37	-1	known	silent	c.582	p.E194	0.850	NULL	pfam_HMG_box_dom,superfamily_HMG_box_dom,smart_HMG_box_dom,pfscan_HMG_box_dom	-	no_errors	HMGB2	HGNC	ENSG00000164104	tier1	-	-	36	0	0.00	26	4	13.33	17	0	0.00	7	0	0.00
RN7SL214P	0	genome.wustl.edu	37	15	78209076	78209077	+	R	INS	-	-	C			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	15	78209076	78209077	-	C	INS	RN7SL214P	ENST00000487317	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000:0.000	-	-	-	no_errors	RN7SL214P	HGNC	ENSG00000242066	tier1			41	0	0.00	44	7	13.73	8	0	0.00	0	0	0.00
TRIM46	0	genome.wustl.edu	37	1	155154488	155154488	+	Silent	SNP	C	C	T			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	1	155154488	155154488	C	T	SNP	TRIM46	ENST00000334634	human	ensembl	74_37	+1	known	silent	c.1749	p.G583	0.898	superfamily_ConA-like_lec_gl_sf,pfscan_B30.2/SPRY	pfam_Znf_B-box,pfam_Znf_C3HC4_RING-type,superfamily_Fibronectin_type3,superfamily_ConA-like_lec_gl_sf,smart_Znf_RING,smart_Znf_B-box,pfscan_B30.2/SPRY,pfscan_Fibronectin_type3,pfscan_Znf_B-box	-	no_errors	TRIM46	HGNC	ENSG00000163462	tier1	-	-	108	0	0.00	106	44	29.33	8	0	0.00	6	1	14.29
BCR	0	genome.wustl.edu	37	22	23658274	23658275	+	R	INS	-	-	TGC			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	22	23658274	23658275	-	TGC	INS	BCR	ENST00000436990	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.000:0.000	-	-	-	no_errors	BCR	HGNC	ENSG00000186716	tier1			14	0	0.00	24	4	14.29	0	0	0.00	0	0	0.00
ENSG00000221279	0	genome.wustl.edu	37	7	110568408	110568413	+	R	DEL	CACACA	CACACA	-			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	CACACA	CACACA					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	7	110568408	110568413	CACACA	-	DEL	ENSG00000221279	ENST00000408352	human	ensembl	74_37	+1	novel	rna	NULL	NULL	0.000:0.003:0.009:0.052:0.060:0.063	-	-	-	no_errors	AC005161.1	Clone_based_ensembl_gene	ENSG00000221279	tier1			0	0	0.00	0	0	0.00	0	0	0.00	0	0	0.00
ENSG00000221388	0	genome.wustl.edu	37	2	213628318	213628325	+	R	DEL	TGTGTGTG	TGTGTGTG	-			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	TGTGTGTG	TGTGTGTG					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	2	213628318	213628325	TGTGTGTG	-	DEL	ENSG00000221388	ENST00000408461	human	ensembl	74_37	-1	novel	rna	NULL	NULL	0.000:0.000:0.000:0.000:0.000:0.000:0.000:0.000	-	-	-	no_errors	AC093865.1	Clone_based_ensembl_gene	ENSG00000221388	tier1			0	0	0.00	0	0	0.00	0	0	0.00	0	0	0.00
ENSG00000221664	0	genome.wustl.edu	37	1	77857164	77857165	+	R	INS	-	-	TA			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	1	77857164	77857165	-	TA	INS	ENSG00000221664	ENST00000408737	human	ensembl	74_37	-1	novel	rna	NULL	NULL	0.989:0.989	-	-	-	no_errors	AC095030.1	Clone_based_ensembl_gene	ENSG00000221664	tier1			45	0	0.00	88	10	10.20	0	0	0.00	0	0	0.00
ENSG00000251966	0	genome.wustl.edu	37	Y	10034012	10034012	+	R	DEL	T	T	-			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	Y	10034012	10034012	T	-	DEL	ENSG00000251966	ENST00000516157	human	ensembl	74_37	+1	novel	rna	NULL	NULL	0.001	-	-	-	no_errors	AC010970.1	Clone_based_ensembl_gene	ENSG00000251966	tier1			18	0	0.00	7	3	30.00	3	0	0.00	0	0	0.00
ENSG00000259241	0	genome.wustl.edu	37	15	51987960	51987960	+	R	DEL	A	A	-			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	15	51987960	51987960	A	-	DEL	ENSG00000259241	ENST00000559918	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.006	-	-	-	no_errors	RP11-313P18.2	Clone_based_vega_gene	ENSG00000259241	tier1			17	0	0.00	23	3	11.54	0	0	0.00	0	0	0.00
FHOD3	0	genome.wustl.edu	37	18	34205614	34205614	+	Missense_Mutation	SNP	G	G	T			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	18	34205614	34205614	G	T	SNP	FHOD3	ENST00000591635	human	ensembl	74_37	+1	putative	missense	c.122	p.R41L	0.014	NULL	pfam_FH2_Formin,smart_FH2_Formin	-	no_errors	FHOD3	HGNC	ENSG00000134775	tier1	-	-	39	0	0.00	39	4	9.30	4	0	0.00	4	0	0.00
NRXN1	0	genome.wustl.edu	37	2	50147836	50147845	+	R	DEL	GTGTGTGTGT	GTGTGTGTGT	-			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	GTGTGTGTGT	GTGTGTGTGT					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	2	50147836	50147845	GTGTGTGTGT	-	DEL	NRXN1	ENST00000484192	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000:0.001:0.005:0.106:0.113:0.127:0.107:0.109:0.093:0.096	-	-	-	no_errors	NRXN1	HGNC	ENSG00000179915	tier1			0	0	0.00	0	0	0.00	0	0	0.00	0	0	0.00
RYR1	0	genome.wustl.edu	37	19	38976304	38976304	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	19	38976304	38976304	G	A	SNP	RYR1	ENST00000359596	human	ensembl	74_37	+1	known	missense	c.5009	p.R1670H	0.999	NULL	pfam_Ca-rel_channel,pfam_Ryanodine_rcpt,pfam_Ryanrecept_TM4-6,pfam_SPRY_rcpt,pfam_Ins145_P3_rcpt,pfam_MIR_motif,pfam_RIH_assoc-dom,pfam_Ion_trans_dom,superfamily_MIR_motif,superfamily_ConA-like_lec_gl_sf,superfamily_MG_RAP_rcpt_1,smart_MIR_motif,smart_SPla/RYanodine_receptor_subgr,prints_Ryan_recept,pfscan_B30.2/SPRY,pfscan_MIR_motif	-	no_errors	RYR1	HGNC	ENSG00000196218	tier1	-	-	9	0	0.00	15	7	31.82	3	0	0.00	1	0	0.00
SLX4	0	genome.wustl.edu	37	16	3646204	3646204	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	16	3646204	3646204	G	A	SNP	SLX4	ENST00000294008	human	ensembl	74_37	-1	known	missense	c.1874	p.A625V	0.694	NULL	pfam_BTB_POZ,superfamily_BTB/POZ_fold,smart_BTB/POZ-like,pfscan_BTB/POZ-like	-	no_errors	SLX4	HGNC	ENSG00000188827	tier1	-	-	18	0	0.00	17	11	39.29	1	0	0.00	0	0	0.00
TDRP	0	genome.wustl.edu	37	8	442474	442474	+	Silent	SNP	G	G	A			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	8	442474	442474	G	A	SNP	TDRP	ENST00000427263	human	ensembl	74_37	-1	known	silent	c.483	p.R161	0.353	NULL	NULL	-	no_errors	TDRP	HGNC	ENSG00000180190	tier1	-	-	27	0	0.00	24	29	54.72	3	0	0.00	2	1	33.33
C4orf19	0	genome.wustl.edu	37	4	37592165	37592165	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	4	37592165	37592165	C	T	SNP	C4orf19	ENST00000284437	human	ensembl	74_37	+1	known	missense	c.488	p.S163F	0.000	NULL	NULL	-	no_errors	C4orf19	HGNC	ENSG00000154274	tier1	-	-	18	0	0.00	35	7	16.28	67	0	0.00	79	2	2.47
CCDC18	0	genome.wustl.edu	37	1	93677634	93677659	+	Frame_Shift_Del	DEL	TTCCCTTCTTTTCTTTTGTGCCAGAA	TTCCCTTCTTTTCTTTTGTGCCAGAA	-			TCGA-DX-A8BM-01A-11D-A417-09	TCGA-DX-A8BM-10B-01D-A41A-09	TTCCCTTCTTTTCTTTTGTGCCAGAA	TTCCCTTCTTTTCTTTTGTGCCAGAA					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	7d7641fa-0687-400b-bf80-67686179fd46	c55775b2-c64d-4761-bbad-9ce34418426b	1	93677634	93677659	TTCCCTTCTTTTCTTTTGTGCCAGAA	-	DEL	CCDC18	ENST00000557479	human	ensembl	74_37	+1	known	frame_shift_del	c.1713_1690	p.R578fs	0.146:0.127:0.051:0.016:0.000:0.000:0.000:0.000:0.003:0.296:0.887:0.894:0.918:0.986:0.995:0.992:0.966:0.782:0.770:0.056:0.047:0.067:0.982:1.000:1.000:1.000	NULL	superfamily_Prefoldin,superfamily_tR-bd_arm	-	no_errors	CCDC18	HGNC	ENSG00000122483	tier1			68	0	0.00	52	3	5.45	68	0	0.00	52	3	5.45