Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	default_gene_name	gene_name_source	 ensembl_gene_id	tier	dbSNP	GMAF	n_ref_count	n_alt_count	normal_vaf	t_ref_count	t_alt_count	tumor_vaf	n_ref_count_val	n_alt_count_val	normal_vaf_val	t_ref_count_val	t_alt_count_val	tumor_vaf_val
PRSS35	0	genome.wustl.edu	37	6	84234189	84234189	+	Silent	SNP	G	G	A			TCGA-DX-A8BR-01A-11D-A417-09	TCGA-DX-A8BR-10B-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef5e3110-5477-450e-b3b3-5d8d696b7657	8f441372-902f-471e-b032-fe958c7ea85f	6	84234189	84234189	G	A	SNP	PRSS35	ENST00000369700	human	ensembl	74_37	+1	known	silent	c.1029	p.S343	0.111	superfamily_Trypsin-like_Pept_dom	pfam_Peptidase_S1,superfamily_Trypsin-like_Pept_dom	-	no_errors	PRSS35	HGNC	ENSG00000146250	tier1	-	-	51	0	0.00	13	6	31.58	121	0	0.00	34	29	46.03
HSP90AB1	0	genome.wustl.edu	37	6	44221273	44221273	+	Missense_Mutation	SNP	C	C	G			TCGA-DX-A8BR-01A-11D-A417-09	TCGA-DX-A8BR-10B-01D-A41A-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef5e3110-5477-450e-b3b3-5d8d696b7657	8f441372-902f-471e-b032-fe958c7ea85f	6	44221273	44221273	C	G	SNP	HSP90AB1	ENST00000353801	human	ensembl	74_37	+1	known	missense	c.2113	p.P705A	1.000	pfam_Hsp90_fam,pirsf_Hsp90_fam	pfam_Hsp90_fam,pfam_HATPase_ATP-bd,superfamily_Ribosomal_S5_D2-typ_fold,superfamily_HATPase_ATP-bd,smart_HATPase_ATP-bd,pirsf_Hsp90_fam,prints_Hsp90_N	-	no_errors	HSP90AB1	HGNC	ENSG00000096384	tier1	-	-	49	0	0.00	25	5	16.67	45	0	0.00	22	4	15.38
BZRAP1	0	genome.wustl.edu	37	17	56382430	56382430	+	Nonsense_Mutation	SNP	C	C	A			TCGA-DX-A8BR-01A-11D-A417-09	TCGA-DX-A8BR-10B-01D-A41A-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef5e3110-5477-450e-b3b3-5d8d696b7657	8f441372-902f-471e-b032-fe958c7ea85f	17	56382430	56382430	C	A	SNP	BZRAP1	ENST00000355701	human	ensembl	74_37	-1	known	nonsense	c.5536	p.E1846*	0.533	NULL	pfam_SH3_2,superfamily_SH3_domain,superfamily_Fibronectin_type3,smart_SH3_domain,smart_Fibronectin_type3,pfscan_Fibronectin_type3,pfscan_SH3_domain	-	no_errors	BZRAP1	HGNC	ENSG00000005379	tier1	-	-	60	0	0.00	40	19	32.20	31	0	0.00	17	3	15.00
TENM3	0	genome.wustl.edu	37	4	183522238	183522238	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A8BR-01A-11D-A417-09	TCGA-DX-A8BR-10B-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef5e3110-5477-450e-b3b3-5d8d696b7657	8f441372-902f-471e-b032-fe958c7ea85f	4	183522238	183522238	G	A	SNP	TENM3	ENST00000406950	human	ensembl	74_37	+1	known	missense	c.673	p.E225K	1.000	pfam_Ten_N	pfam_Ten_N,pfam_EGF_extracell,superfamily_CarboxyPept-like_regulatory,superfamily_Cyt_c-like_dom,smart_EG-like_dom,pfscan_EG-like_dom,tigrfam_YD,tigrfam_Rhs_assc_core	-	no_errors	TENM3	HGNC	ENSG00000218336	tier1	-	-	88	0	0.00	38	119	75.80	46	0	0.00	14	53	79.10
CCDC13	0	genome.wustl.edu	37	3	42781189	42781189	+	Silent	SNP	C	C	T			TCGA-DX-A8BR-01A-11D-A417-09	TCGA-DX-A8BR-10B-01D-A41A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef5e3110-5477-450e-b3b3-5d8d696b7657	8f441372-902f-471e-b032-fe958c7ea85f	3	42781189	42781189	C	T	SNP	CCDC13	ENST00000310232	human	ensembl	74_37	-1	known	silent	c.1101	p.K367	0.944	superfamily_Prefoldin	superfamily_Prefoldin	-	no_errors	CCDC13	HGNC	ENSG00000244607	tier1	-	-	59	0	0.00	11	16	59.26	103	0	0.00	31	48	60.76
COPB2	0	genome.wustl.edu	37	3	139087001	139087001	+	Missense_Mutation	SNP	C	C	G			TCGA-DX-A8BR-01A-11D-A417-09	TCGA-DX-A8BR-10B-01D-A41A-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef5e3110-5477-450e-b3b3-5d8d696b7657	8f441372-902f-471e-b032-fe958c7ea85f	3	139087001	139087001	C	G	SNP	COPB2	ENST00000333188	human	ensembl	74_37	-1	known	missense	c.1531	p.E511Q	1.000	pirsf_COPB2,pfam_Coatomer_WD-assoc_reg	pirsf_COPB2,pfam_Coatomer_WD-assoc_reg,pfam_WD40_repeat,superfamily_WD40_repeat_dom,smart_WD40_repeat,prints_G-protein_beta_WD-40_rep,pfscan_WD40_repeat,pfscan_WD40_repeat_dom	-	no_errors	COPB2	HGNC	ENSG00000184432	tier1	-	-	58	0	0.00	59	16	21.05	131	0	0.00	90	21	18.92
AIM1	0	genome.wustl.edu	37	6	106967940	106967940	+	Missense_Mutation	SNP	G	G	C			TCGA-DX-A8BR-01A-11D-A417-09	TCGA-DX-A8BR-10B-01D-A41A-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef5e3110-5477-450e-b3b3-5d8d696b7657	8f441372-902f-471e-b032-fe958c7ea85f	6	106967940	106967940	G	C	SNP	AIM1	ENST00000369066	human	ensembl	74_37	+1	known	missense	c.1633	p.V545L	0.994	NULL	pfam_Beta/gamma_crystallin,pfam_Ricin_B_lectin,superfamily_G_crystallin-rel,superfamily_Ricin_B_lectin,smart_Beta/gamma_crystallin,smart_Ricin_B_lectin,pfscan_Ricin_B_lectin,pfscan_Beta/gamma_crystallin,prints_Beta/gamma_crystallin	-	no_errors	AIM1	HGNC	ENSG00000112297	tier1	-	-	62	0	0.00	39	9	18.75	118	0	0.00	44	32	42.11
ZNF711	0	genome.wustl.edu	37	X	84520144	84520144	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A8BR-01A-11D-A417-09	TCGA-DX-A8BR-10B-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef5e3110-5477-450e-b3b3-5d8d696b7657	8f441372-902f-471e-b032-fe958c7ea85f	X	84520144	84520144	G	A	SNP	ZNF711	ENST00000395402	human	ensembl	74_37	+1	known	missense	c.733	p.E245K	1.000	pfam_Transcrp_activ_Zfx/Zfy-dom	pfam_Transcrp_activ_Zfx/Zfy-dom,pfam_Znf_C2H2,pfam_Znf_C2H2_jaz,smart_Znf_C2H2-like,pfscan_Znf_C2H2	-	no_errors	ZNF711	HGNC	ENSG00000147180	tier1	-	-	147	0	0.00	66	47	41.59	97	0	0.00	38	23	37.70
ACSL6	0	genome.wustl.edu	37	5	131307262	131307262	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A8BR-01A-11D-A417-09	TCGA-DX-A8BR-10B-01D-A41A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef5e3110-5477-450e-b3b3-5d8d696b7657	8f441372-902f-471e-b032-fe958c7ea85f	5	131307262	131307262	C	T	SNP	ACSL6	ENST00000296869	human	ensembl	74_37	-1	known	missense	c.1415	p.R472Q	1.000	pfam_AMP-dep_Synth/Lig	pfam_AMP-dep_Synth/Lig	-	no_errors	ACSL6	HGNC	ENSG00000164398	tier1	-	-	38	0	0.00	16	9	36.00	188	0	0.00	83	38	31.40
MIR146A	0	genome.wustl.edu	37	5	159912453	159912453	+	R	SNP	A	A	C			TCGA-DX-A8BR-01A-11D-A417-09	TCGA-DX-A8BR-10B-01D-A41A-09	A	A	A	C	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef5e3110-5477-450e-b3b3-5d8d696b7657	8f441372-902f-471e-b032-fe958c7ea85f	5	159912453	159912453	A	C	SNP	MIR146A	ENST00000385201	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	MIR146A	HGNC	ENSG00000253522	tier1	-	-	50	0	0.00	20	12	37.50	112	0	0.00	56	8	12.50
NEURL	0	genome.wustl.edu	37	10	105349291	105349291	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A8BR-01A-11D-A417-09	TCGA-DX-A8BR-10B-01D-A41A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef5e3110-5477-450e-b3b3-5d8d696b7657	8f441372-902f-471e-b032-fe958c7ea85f	10	105349291	105349291	C	T	SNP	NEURL	ENST00000369780	human	ensembl	74_37	+1	known	missense	c.1360	p.R454W	1.000	NULL	pfam_Neu_Z,smart_Neu_Z,pfscan_Neu_Z,pfscan_Znf_RING	-	no_errors	NEURL	HGNC	ENSG00000107954	tier1	-	-	74	0	0.00	70	22	23.66	38	0	0.00	47	17	26.56
ABI3	0	genome.wustl.edu	37	17	47295202	47295202	+	Silent	SNP	C	C	T			TCGA-DX-A8BR-01A-11D-A417-09	TCGA-DX-A8BR-10B-01D-A41A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef5e3110-5477-450e-b3b3-5d8d696b7657	8f441372-902f-471e-b032-fe958c7ea85f	17	47295202	47295202	C	T	SNP	ABI3	ENST00000225941	human	ensembl	74_37	+1	known	silent	c.387	p.N129	1.000	pfam_Abl-interactor_HHR_dom	pfam_Abl-interactor_HHR_dom,pfam_SH3_domain,pfam_SH3_2,superfamily_SH3_domain,smart_SH3_domain,pfscan_SH3_domain,prints_SH3_domain	-	no_errors	ABI3	HGNC	ENSG00000108798	tier1	-	-	41	0	0.00	19	11	36.67	66	0	0.00	37	25	40.32
CNPPD1	0	genome.wustl.edu	37	2	220041005	220041005	+	Missense_Mutation	SNP	A	A	C			TCGA-DX-A8BR-01A-11D-A417-09	TCGA-DX-A8BR-10B-01D-A41A-09	A	A	A	C	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef5e3110-5477-450e-b3b3-5d8d696b7657	8f441372-902f-471e-b032-fe958c7ea85f	2	220041005	220041005	A	C	SNP	CNPPD1	ENST00000360507	human	ensembl	74_37	-1	known	missense	c.118	p.Y40D	1.000	NULL	pfam_Cyclin_PHO80-like,superfamily_Cyclin-like	-	no_errors	CNPPD1	HGNC	ENSG00000115649	tier1	-	-	46	0	0.00	32	9	21.95	90	0	0.00	60	28	31.82
AIM1	0	genome.wustl.edu	37	6	106967377	106967377	+	Missense_Mutation	SNP	G	G	C			TCGA-DX-A8BR-01A-11D-A417-09	TCGA-DX-A8BR-10B-01D-A41A-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef5e3110-5477-450e-b3b3-5d8d696b7657	8f441372-902f-471e-b032-fe958c7ea85f	6	106967377	106967377	G	C	SNP	AIM1	ENST00000369066	human	ensembl	74_37	+1	known	missense	c.1070	p.R357T	0.003	NULL	pfam_Beta/gamma_crystallin,pfam_Ricin_B_lectin,superfamily_G_crystallin-rel,superfamily_Ricin_B_lectin,smart_Beta/gamma_crystallin,smart_Ricin_B_lectin,pfscan_Ricin_B_lectin,pfscan_Beta/gamma_crystallin,prints_Beta/gamma_crystallin	-	no_errors	AIM1	HGNC	ENSG00000112297	tier1	-	-	16	0	0.00	8	5	38.46	122	0	0.00	54	35	39.33
LAMA2	0	genome.wustl.edu	37	6	129833555	129833555	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A8BR-01A-11D-A417-09	TCGA-DX-A8BR-10B-01D-A41A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef5e3110-5477-450e-b3b3-5d8d696b7657	8f441372-902f-471e-b032-fe958c7ea85f	6	129833555	129833555	C	T	SNP	LAMA2	ENST00000421865	human	ensembl	74_37	+1	known	missense	c.8905	p.R2969C	1.000	pfam_Laminin_G,superfamily_ConA-like_lec_gl_sf,smart_Laminin_G,pfscan_Laminin_G	pfam_Laminin_G,pfam_EGF_laminin,pfam_Laminin_N,pfam_Laminin_I,pfam_Laminin_B_type_IV,pfam_Laminin_II,superfamily_ConA-like_lec_gl_sf,superfamily_Galactose-bd-like,superfamily_t-SRE,smart_Laminin_N,smart_EGF_laminin,smart_EG-like_dom,smart_Laminin_B_subgr,smart_Laminin_G,pfscan_Laminin_B_type_IV,pfscan_EGF_laminin,pfscan_Laminin_G,pfscan_Laminin_N	-	no_errors	LAMA2	HGNC	ENSG00000196569	tier1	-	-	114	0	0.00	59	38	39.18	155	0	0.00	75	41	35.34
DH5	0	genome.wustl.edu	37	5	13793644	13793644	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A8BR-01A-11D-A417-09	TCGA-DX-A8BR-10B-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef5e3110-5477-450e-b3b3-5d8d696b7657	8f441372-902f-471e-b032-fe958c7ea85f	5	13793644	13793644	G	A	SNP	DH5	ENST00000265104	human	ensembl	74_37	-1	known	missense	c.8204	p.A2735V	1.000	superfamily_P-loop_NTPase,smart_AAA+_ATPase	pfam_Dynein_heavy_dom,pfam_Dynein_heavy_dom-1,pfam_Dynein_heavy_dom-2,pfam_ATPase_dyneun-rel_AAA,superfamily_P-loop_NTPase,smart_AAA+_ATPase	-	no_errors	DH5	HGNC	ENSG00000039139	tier1	-	-	62	0	0.00	18	11	37.93	119	0	0.00	54	15	21.74
LAIR1	0	genome.wustl.edu	37	19	54866934	54866934	+	Silent	SNP	T	T	C			TCGA-DX-A8BR-01A-11D-A417-09	TCGA-DX-A8BR-10B-01D-A41A-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef5e3110-5477-450e-b3b3-5d8d696b7657	8f441372-902f-471e-b032-fe958c7ea85f	19	54866934	54866934	T	C	SNP	LAIR1	ENST00000391742	human	ensembl	74_37	-1	known	silent	c.807	p.P269	0.000	NULL	smart_Ig_sub	-	no_errors	LAIR1	HGNC	ENSG00000167613	tier1	-	-	18	0	0.00	15	10	40.00	97	0	0.00	43	26	37.68
RUVBL2	0	genome.wustl.edu	37	19	49514351	49514351	+	Splice_Site	SNP	G	G	T			TCGA-DX-A8BR-01A-11D-A417-09	TCGA-DX-A8BR-10B-01D-A41A-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef5e3110-5477-450e-b3b3-5d8d696b7657	8f441372-902f-471e-b032-fe958c7ea85f	19	49514351	49514351	G	T	SNP	RUVBL2	ENST00000595090	human	ensembl	74_37	+1	known	splice_site	c.882+1	e10+1	1.000	-	-	-	no_errors	RUVBL2	HGNC	ENSG00000183207	tier1	-	-	41	0	0.00	36	13	26.53	32	0	0.00	11	9	45.00
OR1F1	0	genome.wustl.edu	37	16	3254752	3254752	+	Missense_Mutation	SNP	G	G	C			TCGA-DX-A8BR-01A-11D-A417-09	TCGA-DX-A8BR-10B-01D-A41A-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef5e3110-5477-450e-b3b3-5d8d696b7657	8f441372-902f-471e-b032-fe958c7ea85f	16	3254752	3254752	G	C	SNP	OR1F1	ENST00000304646	human	ensembl	74_37	+1	known	missense	c.506	p.C169S	1.000	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR1F1	HGNC	ENSG00000168124	tier1	-	-	30	0	0.00	11	6	35.29	55	0	0.00	24	13	34.21
MYL6	0	genome.wustl.edu	37	12	56553915	56553915	+	Missense_Mutation	SNP	A	A	G			TCGA-DX-A8BR-01A-11D-A417-09	TCGA-DX-A8BR-10B-01D-A41A-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef5e3110-5477-450e-b3b3-5d8d696b7657	8f441372-902f-471e-b032-fe958c7ea85f	12	56553915	56553915	A	G	SNP	MYL6	ENST00000547649	human	ensembl	74_37	+1	known	missense	c.332	p.H111R	1.000	smart_EF_hand_dom,pfscan_EF_hand_dom	smart_EF_hand_dom,pfscan_EF_hand_dom	-	no_errors	MYL6	HGNC	ENSG00000092841	tier1	-	-	71	0	0.00	8	6	42.86	77	0	0.00	36	15	29.41
PDGFRB	0	genome.wustl.edu	37	5	149501616	149501616	+	R	SNP	G	G	A			TCGA-DX-A8BR-01A-11D-A417-09	TCGA-DX-A8BR-10B-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef5e3110-5477-450e-b3b3-5d8d696b7657	8f441372-902f-471e-b032-fe958c7ea85f	5	149501616	149501616	G	A	SNP	PDGFRB	ENST00000519575	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.078	-	-	-	no_errors	PDGFRB	HGNC	ENSG00000113721	tier1	-	-	30	0	0.00	19	5	20.83	51	0	0.00	28	12	29.27
ITIH5	0	genome.wustl.edu	37	10	7657968	7657968	+	Missense_Mutation	SNP	T	T	C			TCGA-DX-A8BR-01A-11D-A417-09	TCGA-DX-A8BR-10B-01D-A41A-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef5e3110-5477-450e-b3b3-5d8d696b7657	8f441372-902f-471e-b032-fe958c7ea85f	10	7657968	7657968	T	C	SNP	ITIH5	ENST00000256861	human	ensembl	74_37	-1	known	missense	c.916	p.M306V	1.000	pfam_VWF_A,smart_VWF_A,pfscan_VWF_A	pfam_ITI_HC_C,pfam_VIT,pfam_VWF_A,smart_VIT,smart_VWF_A,pfscan_VWF_A	-	no_errors	ITIH5	HGNC	ENSG00000123243	tier1	-	-	95	0	0.00	22	25	53.19	159	0	0.00	48	40	45.45
HIST1H2AC	0	genome.wustl.edu	37	6	26124497	26124497	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A8BR-01A-11D-A417-09	TCGA-DX-A8BR-10B-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef5e3110-5477-450e-b3b3-5d8d696b7657	8f441372-902f-471e-b032-fe958c7ea85f	6	26124497	26124497	G	A	SNP	HIST1H2AC	ENST00000314088	human	ensembl	74_37	+1	known	missense	c.37	p.A13T	1.000	superfamily_Histone-fold,smart_Histone_H2A	pfam_Histone_core_D,pfam_CBFA_NFYB_domain,superfamily_Histone-fold,smart_Histone_H2A,prints_Histone_H2A	-	no_errors	HIST1H2AC	HGNC	ENSG00000180573	tier1	-	-	61	0	0.00	38	20	34.48	61	0	0.00	34	23	40.35
C4orf22	0	genome.wustl.edu	37	4	81791167	81791167	+	Missense_Mutation	SNP	C	C	G			TCGA-DX-A8BR-01A-11D-A417-09	TCGA-DX-A8BR-10B-01D-A41A-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef5e3110-5477-450e-b3b3-5d8d696b7657	8f441372-902f-471e-b032-fe958c7ea85f	4	81791167	81791167	C	G	SNP	C4orf22	ENST00000508675	human	ensembl	74_37	+1	known	missense	c.405	p.D135E	0.999	NULL	NULL	-	no_errors	C4orf22	HGNC	ENSG00000197826	tier1	-	-	62	0	0.00	18	15	45.45	123	0	0.00	68	20	22.73
COPB2	0	genome.wustl.edu	37	3	139085946	139085946	+	Missense_Mutation	SNP	C	C	G			TCGA-DX-A8BR-01A-11D-A417-09	TCGA-DX-A8BR-10B-01D-A41A-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef5e3110-5477-450e-b3b3-5d8d696b7657	8f441372-902f-471e-b032-fe958c7ea85f	3	139085946	139085946	C	G	SNP	COPB2	ENST00000333188	human	ensembl	74_37	-1	known	missense	c.1587	p.W529C	1.000	pirsf_COPB2,pfam_Coatomer_WD-assoc_reg	pirsf_COPB2,pfam_Coatomer_WD-assoc_reg,pfam_WD40_repeat,superfamily_WD40_repeat_dom,smart_WD40_repeat,prints_G-protein_beta_WD-40_rep,pfscan_WD40_repeat,pfscan_WD40_repeat_dom	-	no_errors	COPB2	HGNC	ENSG00000184432	tier1	-	-	122	0	0.00	80	25	23.81	152	0	0.00	113	23	16.79
BMS1P17	0	genome.wustl.edu	37	14	19670720	19670720	+	R	SNP	A	A	T			TCGA-DX-A8BR-01A-11D-A417-09	TCGA-DX-A8BR-10B-01D-A41A-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef5e3110-5477-450e-b3b3-5d8d696b7657	8f441372-902f-471e-b032-fe958c7ea85f	14	19670720	19670720	A	T	SNP	BMS1P17	ENST00000550512	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.051	-	-	-	no_errors	BMS1P17	HGNC	ENSG00000228294	tier1	-	-	19	0	0.00	9	6	40.00	45	0	0.00	26	16	38.10
AHCTF1	0	genome.wustl.edu	37	1	247063653	247063653	+	Missense_Mutation	SNP	C	C	A			TCGA-DX-A8BR-01A-11D-A417-09	TCGA-DX-A8BR-10B-01D-A41A-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef5e3110-5477-450e-b3b3-5d8d696b7657	8f441372-902f-471e-b032-fe958c7ea85f	1	247063653	247063653	C	A	SNP	AHCTF1	ENST00000326225	human	ensembl	74_37	-1	known	missense	c.1263	p.M421I	1.000	NULL	superfamily_Quinonprotein_ADH-like_supfam	-	no_errors	AHCTF1	HGNC	ENSG00000153207	tier1	-	-	102	0	0.00	16	27	62.79	102	0	0.00	16	31	65.96
ZNF90	0	genome.wustl.edu	37	19	20229235	20229235	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A8BR-01A-11D-A417-09	TCGA-DX-A8BR-10B-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef5e3110-5477-450e-b3b3-5d8d696b7657	8f441372-902f-471e-b032-fe958c7ea85f	19	20229235	20229235	G	A	SNP	ZNF90	ENST00000418063	human	ensembl	74_37	+1	known	missense	c.872	p.G291D	0.989	smart_Znf_C2H2-like,pfscan_Znf_C2H2	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF90	HGNC	ENSG00000213988	tier1	-	-	65	0	0.00	33	20	37.74	17	0	0.00	11	7	38.89
WDR63	0	genome.wustl.edu	37	1	85555896	85555896	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A8BR-01A-11D-A417-09	TCGA-DX-A8BR-10B-01D-A41A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef5e3110-5477-450e-b3b3-5d8d696b7657	8f441372-902f-471e-b032-fe958c7ea85f	1	85555896	85555896	C	T	SNP	WDR63	ENST00000294664	human	ensembl	74_37	+1	known	missense	c.838	p.L280F	0.999	NULL	pfam_WD40_repeat,superfamily_WD40_repeat_dom,smart_WD40_repeat	-	no_errors	WDR63	HGNC	ENSG00000162643	tier1	-	-	99	0	0.00	58	20	25.64	77	0	0.00	34	22	39.29
LAMTOR1	0	genome.wustl.edu	37	11	71809346	71809346	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A8BR-01A-11D-A417-09	TCGA-DX-A8BR-10B-01D-A41A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef5e3110-5477-450e-b3b3-5d8d696b7657	8f441372-902f-471e-b032-fe958c7ea85f	11	71809346	71809346	C	T	SNP	LAMTOR1	ENST00000278671	human	ensembl	74_37	-1	known	missense	c.382	p.D128N	1.000	NULL	NULL	-	no_errors	LAMTOR1	HGNC	ENSG00000149357	tier1	-	-	36	0	0.00	16	9	36.00	29	0	0.00	25	5	16.67
PDE1C	0	genome.wustl.edu	37	7	31864525	31864525	+	Silent	SNP	G	G	A			TCGA-DX-A8BR-01A-11D-A417-09	TCGA-DX-A8BR-10B-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef5e3110-5477-450e-b3b3-5d8d696b7657	8f441372-902f-471e-b032-fe958c7ea85f	7	31864525	31864525	G	A	SNP	PDE1C	ENST00000321453	human	ensembl	74_37	-1	known	silent	c.1362	p.I454	0.834	pfam_PDEase_catalytic_dom	pfam_PDEase_catalytic_dom,pfam_PDEase_N,smart_HD/PDEase_dom,prints_PDEase	-	no_errors	PDE1C	HGNC	ENSG00000154678	tier1	-	-	56	0	0.00	15	19	55.88	124	0	0.00	28	29	50.88
MYH11	0	genome.wustl.edu	37	16	15832545	15832545	+	Missense_Mutation	SNP	C	C	G			TCGA-DX-A8BR-01A-11D-A417-09	TCGA-DX-A8BR-10B-01D-A41A-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef5e3110-5477-450e-b3b3-5d8d696b7657	8f441372-902f-471e-b032-fe958c7ea85f	16	15832545	15832545	C	G	SNP	MYH11	ENST00000396324	human	ensembl	74_37	-1	known	missense	c.3019	p.E1007Q	1.000	superfamily_Prefoldin	pfam_Myosin_head_motor_dom,pfam_Myosin_tail,pfam_Myosin_N,superfamily_P-loop_NTPase,superfamily_Prefoldin,superfamily_t-SRE,smart_Myosin_head_motor_dom,smart_IQ_motif_EF-hand-BS,prints_Myosin_head_motor_dom,pfscan_IQ_motif_EF-hand-BS	-	no_errors	MYH11	HGNC	ENSG00000133392	tier1	-	-	88	0	0.00	47	22	31.88	117	0	0.00	79	24	23.08
AIM1	0	genome.wustl.edu	37	6	106968274	106968274	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A8BR-01A-11D-A417-09	TCGA-DX-A8BR-10B-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef5e3110-5477-450e-b3b3-5d8d696b7657	8f441372-902f-471e-b032-fe958c7ea85f	6	106968274	106968274	G	A	SNP	AIM1	ENST00000369066	human	ensembl	74_37	+1	known	missense	c.1967	p.G656E	0.001	NULL	pfam_Beta/gamma_crystallin,pfam_Ricin_B_lectin,superfamily_G_crystallin-rel,superfamily_Ricin_B_lectin,smart_Beta/gamma_crystallin,smart_Ricin_B_lectin,pfscan_Ricin_B_lectin,pfscan_Beta/gamma_crystallin,prints_Beta/gamma_crystallin	-	no_errors	AIM1	HGNC	ENSG00000112297	tier1	-	-	21	0	0.00	19	8	29.63	97	0	0.00	61	28	31.11
CSPG5	0	genome.wustl.edu	37	3	47610660	47610660	+	Silent	SNP	G	G	A			TCGA-DX-A8BR-01A-11D-A417-09	TCGA-DX-A8BR-10B-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef5e3110-5477-450e-b3b3-5d8d696b7657	8f441372-902f-471e-b032-fe958c7ea85f	3	47610660	47610660	G	A	SNP	CSPG5	ENST00000383738	human	ensembl	74_37	-1	known	silent	c.1440	p.A480	0.959	pfam_Neural_ProG_Cyt	pfam_Chon_Sulph_att,pfam_Neural_ProG_Cyt	-	no_errors	CSPG5	HGNC	ENSG00000114646	tier1	-	-	90	0	0.00	13	31	70.45	122	0	0.00	34	33	49.25
PCDHA7	0	genome.wustl.edu	37	5	140214124	140214124	+	Silent	SNP	G	G	A			TCGA-DX-A8BR-01A-11D-A417-09	TCGA-DX-A8BR-10B-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef5e3110-5477-450e-b3b3-5d8d696b7657	8f441372-902f-471e-b032-fe958c7ea85f	5	140214124	140214124	G	A	SNP	PCDHA7	ENST00000525929	human	ensembl	74_37	+1	known	silent	c.156	p.L52	0.998	pfam_Cadherin_N,superfamily_Cadherin-like,smart_Cadherin	pfam_Cadherin,pfam_Cadherin_N,superfamily_Cadherin-like,smart_Cadherin,prints_Cadherin,pfscan_Cadherin	-	no_errors	PCDHA7	HGNC	ENSG00000204963	tier1	-	-	100	0	0.00	48	21	30.43	41	0	0.00	14	15	51.72
CDH4	0	genome.wustl.edu	37	20	60511837	60511837	+	Missense_Mutation	SNP	G	G	T			TCGA-DX-A8BR-01A-11D-A417-09	TCGA-DX-A8BR-10B-01D-A41A-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef5e3110-5477-450e-b3b3-5d8d696b7657	8f441372-902f-471e-b032-fe958c7ea85f	20	60511837	60511837	G	T	SNP	CDH4	ENST00000360469	human	ensembl	74_37	+1	known	missense	c.2587	p.D863Y	1.000	pfam_Cadherin_cytoplasmic-dom	pfam_Cadherin,pfam_Cadherin_cytoplasmic-dom,pfam_Cadherin_pro_dom,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin,prints_Cadherin,prints_Cadherin/Desmocollin	-	no_errors	CDH4	HGNC	ENSG00000179242	tier1	-	-	39	0	0.00	15	11	42.31	45	0	0.00	22	17	43.59
MUC21	0	genome.wustl.edu	37	6	30954828	30954828	+	Silent	SNP	A	A	C			TCGA-DX-A8BR-01A-11D-A417-09	TCGA-DX-A8BR-10B-01D-A41A-09	A	A	A	C	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef5e3110-5477-450e-b3b3-5d8d696b7657	8f441372-902f-471e-b032-fe958c7ea85f	6	30954828	30954828	A	C	SNP	MUC21	ENST00000376296	human	ensembl	74_37	+1	known	silent	c.876	p.T292	0.000	NULL	NULL	-	no_errors	MUC21	HGNC	ENSG00000204544	tier1	-	-	63	0	0.00	24	13	35.14	26	0	0.00	12	9	42.86
ALPL	0	genome.wustl.edu	37	1	21903986	21903986	+	Missense_Mutation	SNP	G	G	C			TCGA-DX-A8BR-01A-11D-A417-09	TCGA-DX-A8BR-10B-01D-A41A-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef5e3110-5477-450e-b3b3-5d8d696b7657	8f441372-902f-471e-b032-fe958c7ea85f	1	21903986	21903986	G	C	SNP	ALPL	ENST00000374832	human	ensembl	74_37	+1	known	missense	c.1420	p.V474L	1.000	pfam_Alkaline_phosphatase,superfamily_Alkaline_phosphatase_core,smart_Alkaline_phosphatase	pfam_Alkaline_phosphatase,superfamily_Alkaline_phosphatase_core,smart_Alkaline_phosphatase,prints_Alkaline_phosphatase	-	no_errors	ALPL	HGNC	ENSG00000162551	tier1	-	-	65	0	0.00	31	19	38.00	20	0	0.00	11	10	45.45
PIGB	0	genome.wustl.edu	37	15	55647016	55647016	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A8BR-01A-11D-A417-09	TCGA-DX-A8BR-10B-01D-A41A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef5e3110-5477-450e-b3b3-5d8d696b7657	8f441372-902f-471e-b032-fe958c7ea85f	15	55647016	55647016	C	T	SNP	PIGB	ENST00000164305	human	ensembl	74_37	+1	known	missense	c.1358	p.P453L	0.930	NULL	pfam_GPI_mannosylTrfase	-	no_errors	PIGB	HGNC	ENSG00000069943	tier1	-	-	37	0	0.00	21	16	43.24	116	0	0.00	42	23	35.38
ALDH9A1	0	genome.wustl.edu	37	1	165649861	165649861	+	Nonsense_Mutation	SNP	C	C	A			TCGA-DX-A8BR-01A-11D-A417-09	TCGA-DX-A8BR-10B-01D-A41A-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef5e3110-5477-450e-b3b3-5d8d696b7657	8f441372-902f-471e-b032-fe958c7ea85f	1	165649861	165649861	C	A	SNP	ALDH9A1	ENST00000354775	human	ensembl	74_37	-1	known	nonsense	c.652	p.E218*	1.000	pfam_Aldehyde_DH_dom,superfamily_Ald_DH/histidinol_DH	pfam_Aldehyde_DH_dom,superfamily_Ald_DH/histidinol_DH	-	no_errors	ALDH9A1	HGNC	ENSG00000143149	tier1	-	-	74	0	0.00	59	22	27.16	156	0	0.00	184	28	13.15
USP44	0	genome.wustl.edu	37	12	95927128	95927128	+	Frame_Shift_Del	DEL	A	A	-			TCGA-DX-A8BR-01A-11D-A417-09	TCGA-DX-A8BR-10B-01D-A41A-09	A	A	A	-	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef5e3110-5477-450e-b3b3-5d8d696b7657	8f441372-902f-471e-b032-fe958c7ea85f	12	95927128	95927128	A	-	DEL	USP44	ENST00000258499	human	ensembl	74_37	-1	known	frame_shift_del	c.905	p.L302fs	1.000	pfam_Peptidase_C19/C67,pfscan_Peptidase_C19/C67	pfam_Peptidase_C19/C67,pfam_Znf_UBP,smart_Znf_UBP,pfscan_Znf_UBP,pfscan_Peptidase_C19/C67	-	no_errors	USP44	HGNC	ENSG00000136014	tier1			36	0	0.00	23	6	20.69	121	0	0.00	51	10	16.39
BMS1	0	genome.wustl.edu	37	10	43285807	43285807	+	Missense_Mutation	SNP	A	A	G			TCGA-DX-A8BR-01A-11D-A417-09	TCGA-DX-A8BR-10B-01D-A41A-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef5e3110-5477-450e-b3b3-5d8d696b7657	8f441372-902f-471e-b032-fe958c7ea85f	10	43285807	43285807	A	G	SNP	BMS1	ENST00000374518	human	ensembl	74_37	+1	known	missense	c.484	p.M162V	1.000	pfam_EF_GTP-bd_dom,superfamily_P-loop_NTPase	pfam_BMS1_TSR1_C,pfam_AARP2CN,pfam_EF_GTP-bd_dom,superfamily_P-loop_NTPase,smart_AARP2CN	-	no_errors	BMS1	HGNC	ENSG00000165733	tier1	-	-	349	0	0.00	178	81	31.27	26	0	0.00	9	6	40.00
DYRK4	0	genome.wustl.edu	37	12	4705324	4705324	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A8BR-01A-11D-A417-09	TCGA-DX-A8BR-10B-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef5e3110-5477-450e-b3b3-5d8d696b7657	8f441372-902f-471e-b032-fe958c7ea85f	12	4705324	4705324	G	A	SNP	DYRK4	ENST00000010132	human	ensembl	74_37	+1	known	missense	c.292	p.D98N	1.000	superfamily_Kinase-like_dom	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	-	no_errors	DYRK4	HGNC	ENSG00000010219	tier1	-	-	45	0	0.00	11	5	31.25	103	0	0.00	9	20	68.97
SOGA2	0	genome.wustl.edu	37	18	8831766	8831766	+	Silent	SNP	C	C	T			TCGA-DX-A8BR-01A-11D-A417-09	TCGA-DX-A8BR-10B-01D-A41A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef5e3110-5477-450e-b3b3-5d8d696b7657	8f441372-902f-471e-b032-fe958c7ea85f	18	8831766	8831766	C	T	SNP	SOGA2	ENST00000306285	human	ensembl	74_37	+1	known	silent	c.2859	p.G953	0.000	NULL	NULL	-	no_errors	SOGA2	HGNC	ENSG00000168502	tier1	-	-	32	0	0.00	19	6	24.00	10	0	0.00	5	4	44.44
IFT46	0	genome.wustl.edu	37	11	118427683	118427685	+	In_Frame_Del	DEL	ATC	ATC	-			TCGA-DX-A8BR-01A-11D-A417-09	TCGA-DX-A8BR-10B-01D-A41A-09	ATC	ATC	ATC	-	ATC	ATC	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef5e3110-5477-450e-b3b3-5d8d696b7657	8f441372-902f-471e-b032-fe958c7ea85f	11	118427683	118427685	ATC	-	DEL	IFT46	ENST00000264020	human	ensembl	74_37	-1	known	in_frame_del	c.276_274	p.D92in_frame_del	1.000:1.000:0.999	NULL	pfam_Intraflagellar_transp_cmplxB	-	no_errors	IFT46	HGNC	ENSG00000118096	tier1			47	0	0.00	30	3	9.09	90	0	0.00	87	6	6.45
EBPL	0	genome.wustl.edu	37	13	50237243	50237243	+	Silent	SNP	C	C	A			TCGA-DX-A8BR-01A-11D-A417-09	TCGA-DX-A8BR-10B-01D-A41A-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef5e3110-5477-450e-b3b3-5d8d696b7657	8f441372-902f-471e-b032-fe958c7ea85f	13	50237243	50237243	C	A	SNP	EBPL	ENST00000242827	human	ensembl	74_37	-1	known	silent	c.330	p.G110	0.036	pfam_EBP	pfam_EBP	-	no_errors	EBPL	HGNC	ENSG00000123179	tier1	-	-	79	0	0.00	16	3	15.79	17	0	0.00	7	0	0.00
ENSG00000221244	0	genome.wustl.edu	37	5	1004310	1004311	+	R	INS	-	-	GGGTGTGTGT			TCGA-DX-A8BR-01A-11D-A417-09	TCGA-DX-A8BR-10B-01D-A41A-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef5e3110-5477-450e-b3b3-5d8d696b7657	8f441372-902f-471e-b032-fe958c7ea85f	5	1004310	1004311	-	GGGTGTGTGT	INS	ENSG00000221244	ENST00000408317	human	ensembl	74_37	+1	novel	rna	NULL	NULL	0.034:0.057	-	-	-	no_errors	AC116351.2	Clone_based_ensembl_gene	ENSG00000221244	tier1			16	0	0.00	3	0	0.00	16	0	0.00	3	0	0.00
ENSG00000251226	0	genome.wustl.edu	37	11	134605777	134605777	+	R	SNP	C	C	G			TCGA-DX-A8BR-01A-11D-A417-09	TCGA-DX-A8BR-10B-01D-A41A-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef5e3110-5477-450e-b3b3-5d8d696b7657	8f441372-902f-471e-b032-fe958c7ea85f	11	134605777	134605777	C	G	SNP	ENSG00000251226	ENST00000513405	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.003	-	-	-	no_errors	RP11-469N6.1	Clone_based_vega_gene	ENSG00000251226	tier1	rs7104522	-	13	0	0.00	9	11	55.00	0	0	0.00	0	0	0.00
KRT1	0	genome.wustl.edu	37	12	53069193	53069193	+	Silent	SNP	G	G	A			TCGA-DX-A8BR-01A-11D-A417-09	TCGA-DX-A8BR-10B-01D-A41A-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef5e3110-5477-450e-b3b3-5d8d696b7657	8f441372-902f-471e-b032-fe958c7ea85f	12	53069193	53069193	G	A	SNP	KRT1	ENST00000252244	human	ensembl	74_37	-1	known	silent	c.1719	p.G573	0.811	NULL	pfam_IF,superfamily_Prefoldin,prints_Keratin_II	-	no_errors	KRT1	HGNC	ENSG00000167768	tier1	-	-	43	0	0.00	24	12	33.33	1	0	0.00	0	0	0.00
KRTAP9-9	0	genome.wustl.edu	37	17	39411670	39411670	+	Silent	SNP	T	T	C			TCGA-DX-A8BR-01A-11D-A417-09	TCGA-DX-A8BR-10B-01D-A41A-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef5e3110-5477-450e-b3b3-5d8d696b7657	8f441372-902f-471e-b032-fe958c7ea85f	17	39411670	39411670	T	C	SNP	KRTAP9-9	ENST00000394008	human	ensembl	74_37	+1	known	silent	c.33	p.P11	0.053	NULL	NULL	-	no_errors	KRTAP9-9	HGNC	ENSG00000198083	tier1	-	-	37	0	0.00	30	4	11.76	0	0	0.00	0	0	0.00
SENP3	0	genome.wustl.edu	37	17	7475163	7475198	+	Splice_Site	DEL	ATATATATATATATATATATATATATATATATATAT	ATATATATATATATATATATATATATATATATATAT	-			TCGA-DX-A8BR-01A-11D-A417-09	TCGA-DX-A8BR-10B-01D-A41A-09	ATATATATATATATATATATATATATATATATATAT	ATATATATATATATATATATATATATATATATATAT					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef5e3110-5477-450e-b3b3-5d8d696b7657	8f441372-902f-471e-b032-fe958c7ea85f	17	7475163	7475198	ATATATATATATATATATATATATATATATATATAT	-	DEL	SENP3	ENST00000429205	human	ensembl	74_37	+1	known	splice_site_del	c.1725+27_62	e12-1	1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:0.995:0.988:0.984:0.978:0.977:0.973:0.975:0.974:0.977:0.977:0.976:0.974:0.976:0.976:0.974:0.970:0.972:0.972:0.969:0.964:0.963:0.960:0.953:0.941:0.939	-	-	-	no_errors	SENP3	HGNC	ENSG00000161956	tier1			2	0	0.00	0	0	0.00	2	0	0.00	0	0	0.00
SPEG	0	genome.wustl.edu	37	2	220330668	220330669	+	R	INS	-	-	GT			TCGA-DX-A8BR-01A-11D-A417-09	TCGA-DX-A8BR-10B-01D-A41A-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef5e3110-5477-450e-b3b3-5d8d696b7657	8f441372-902f-471e-b032-fe958c7ea85f	2	220330668	220330669	-	GT	INS	SPEG	ENST00000462545	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.000:0.003	-	-	-	no_errors	SPEG	HGNC	ENSG00000072195	tier1			21	0	0.00	13	4	23.53	0	0	0.00	0	0	0.00
WNK2	0	genome.wustl.edu	37	9	96061384	96061384	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A8BR-01A-11D-A417-09	TCGA-DX-A8BR-10B-01D-A41A-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef5e3110-5477-450e-b3b3-5d8d696b7657	8f441372-902f-471e-b032-fe958c7ea85f	9	96061384	96061384	G	A	SNP	WNK2	ENST00000297954	human	ensembl	74_37	+1	known	missense	c.6067	p.A2023T	0.998	NULL	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Kinase_OSR1/WNK_CCT,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	-	no_errors	WNK2	HGNC	ENSG00000165238	tier1	rs147749673	-	59	0	0.00	43	15	25.86	4	0	0.00	7	4	36.36