Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	default_gene_name	gene_name_source	 ensembl_gene_id	tier	dbSNP	GMAF	n_ref_count	n_alt_count	normal_vaf	t_ref_count	t_alt_count	tumor_vaf	n_ref_count_val	n_alt_count_val	normal_vaf_val	t_ref_count_val	t_alt_count_val	tumor_vaf_val
SGK223	0	genome.wustl.edu	37	8	8235474	8235474	+	Missense_Mutation	SNP	G	G	T			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	8	8235474	8235474	G	T	SNP	SGK223	ENST00000330777	human	ensembl	74_37	-1	known	missense	c.445	p.P149T	0.000	NULL	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,pfscan_Prot_kinase_dom	-	no_errors	SGK223	Uniprot_gn	ENSG00000182319	tier1	-	-	70	0	0.00	32	16	33.33	33	0	0.00	43	13	23.21
SGK223	0	genome.wustl.edu	37	8	8185770	8185770	+	Missense_Mutation	SNP	G	G	T			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	8	8185770	8185770	G	T	SNP	SGK223	ENST00000330777	human	ensembl	74_37	-1	known	missense	c.2522	p.A841E	0.038	NULL	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,pfscan_Prot_kinase_dom	-	no_errors	SGK223	Uniprot_gn	ENSG00000182319	tier1	-	-	61	0	0.00	30	14	31.82	117	0	0.00	55	20	26.67
PZP	0	genome.wustl.edu	37	12	9307325	9307325	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	12	9307325	9307325	C	T	SNP	PZP	ENST00000261336	human	ensembl	74_37	-1	known	missense	c.3661	p.A1221T	0.916	pfam_A2M_comp,superfamily_Terpenoid_cyclase/PrenylTrfase	pfam_A2M_comp,pfam_A2M_N_2,pfam_Macroglobln_a2,pfam_A-macroglobulin_rcpt-bd,pfam_A2M_N,pfam_MacrogloblnA2_thiol-ester-bond,pfam_SV_autoAg,superfamily_Terpenoid_cyclase/PrenylTrfase,superfamily_A-macroglobulin_rcpt-bd	-	no_errors	PZP	HGNC	ENSG00000126838	tier1	-	-	78	0	0.00	40	15	27.27	39	0	0.00	23	8	25.81
ATP6V0A4	0	genome.wustl.edu	37	7	138432198	138432198	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	7	138432198	138432198	C	T	SNP	ATP6V0A4	ENST00000310018	human	ensembl	74_37	-1	known	missense	c.1292	p.R431H	0.000	pfam_V-ATPase_116kDa_su	pfam_V-ATPase_116kDa_su	-	no_errors	ATP6V0A4	HGNC	ENSG00000105929	tier1	-	-	46	0	0.00	48	26	35.14	108	0	0.00	73	23	23.96
BRD7	0	genome.wustl.edu	37	16	50357503	50357503	+	Nonsense_Mutation	SNP	C	C	A			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	16	50357503	50357503	C	A	SNP	BRD7	ENST00000394689	human	ensembl	74_37	-1	known	nonsense	c.1438	p.E480*	0.789	pfam_DUF3512	pfam_DUF3512,pfam_Bromodomain,superfamily_Bromodomain,smart_Bromodomain,prints_Bromodomain,pfscan_Bromodomain	-	no_errors	BRD7	HGNC	ENSG00000166164	tier1	-	-	48	0	0.00	22	16	42.11	89	0	0.00	26	12	31.58
IFITM1	0	genome.wustl.edu	37	11	314332	314332	+	Silent	SNP	C	C	T			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	11	314332	314332	C	T	SNP	IFITM1	ENST00000328221	human	ensembl	74_37	+1	known	silent	c.162	p.F54	0.997	pfam_CD225/Dispanin_fam	pfam_CD225/Dispanin_fam	-	no_errors	IFITM1	HGNC	ENSG00000185885	tier1	-	-	55	0	0.00	52	19	26.76	35	0	0.00	15	10	40.00
USH2A	0	genome.wustl.edu	37	1	216011349	216011349	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	1	216011349	216011349	G	A	SNP	USH2A	ENST00000366943	human	ensembl	74_37	-1	known	missense	c.9355	p.R3119C	0.128	superfamily_Fibronectin_type3,smart_Fibronectin_type3	pfam_Fibronectin_type3,pfam_EGF_laminin,pfam_Laminin_G,superfamily_ConA-like_lec_gl_sf,superfamily_Fibronectin_type3,smart_LamG-like,smart_Laminin_N,smart_EGF_laminin,smart_Fibronectin_type3,smart_Laminin_G,pfscan_EGF_laminin,pfscan_Fibronectin_type3,pfscan_Laminin_G,pfscan_Laminin_N	-	no_errors	USH2A	HGNC	ENSG00000042781	tier1	-	-	37	0	0.00	9	20	68.97	178	0	0.00	44	60	57.69
HTR1D	0	genome.wustl.edu	37	1	23520075	23520075	+	Missense_Mutation	SNP	A	A	T			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	1	23520075	23520075	A	T	SNP	HTR1D	ENST00000314113	human	ensembl	74_37	-1	known	missense	c.638	p.L213H	1.000	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_GPCR_Rhodpsn	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_GPCR_Rhodpsn,prints_5HT1D_rcpt,prints_5HT_rcpt	-	no_errors	HTR1D	HGNC	ENSG00000179546	tier1	-	-	26	0	0.00	12	12	50.00	156	0	0.00	33	14	29.17
CECR2	0	genome.wustl.edu	37	22	18022400	18022400	+	Silent	SNP	G	G	A			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	22	18022400	18022400	G	A	SNP	CECR2	ENST00000400573	human	ensembl	74_37	+1	novel	silent	c.2502	p.V834	0.274	NULL	pfam_Bromodomain,superfamily_Bromodomain,smart_Bromodomain,prints_Bromodomain,pfscan_Bromodomain	-	no_errors	CECR2	HGNC	ENSG00000099954	tier1	-	-	56	0	0.00	23	29	54.72	37	0	0.00	21	18	46.15
ACBD6	0	genome.wustl.edu	37	1	180257470	180257470	+	R	SNP	T	T	C			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	1	180257470	180257470	T	C	SNP	ACBD6	ENST00000475338	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	ACBD6	HGNC	ENSG00000135847	tier1	-	-	42	0	0.00	9	27	75.00	121	0	0.00	35	36	50.70
IL20RA	0	genome.wustl.edu	37	6	137323068	137323068	+	Missense_Mutation	SNP	G	G	T			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	6	137323068	137323068	G	T	SNP	IL20RA	ENST00000316649	human	ensembl	74_37	-1	known	missense	c.1289	p.T430K	0.000	NULL	pfam_Interferon_alpha/beta_rcpt_bsu,superfamily_Fibronectin_type3	-	no_errors	IL20RA	HGNC	ENSG00000016402	tier1	-	-	49	0	0.00	23	14	37.84	116	0	0.00	60	26	30.23
GPR37	0	genome.wustl.edu	37	7	124386687	124386687	+	Silent	SNP	C	C	A			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	7	124386687	124386687	C	A	SNP	GPR37	ENST00000303921	human	ensembl	74_37	-1	known	silent	c.1734	p.V578	0.999	NULL	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_GPR37_orph,prints_GPCR_Rhodpsn	-	no_errors	GPR37	HGNC	ENSG00000170775	tier1	-	-	54	0	0.00	22	21	48.84	133	0	0.00	69	60	46.51
CPAMD8	0	genome.wustl.edu	37	19	17086902	17086902	+	Silent	SNP	G	G	T			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	19	17086902	17086902	G	T	SNP	CPAMD8	ENST00000443236	human	ensembl	74_37	-1	known	silent	c.1959	p.I653	0.097	pfam_A2M_N_2	pfam_A2M_comp,pfam_A2M_N_2,pfam_Methyltransf_FA,pfam_Macroglobln_a2,pfam_A-macroglobulin_rcpt-bd,pfam_A2M_N,pfam_MacrogloblnA2_thiol-ester-bond,pfam_Kazal_dom,superfamily_Terpenoid_cyclase/PrenylTrfase,superfamily_A-macroglobulin_rcpt-bd,smart_Kazal_dom	-	no_errors	CPAMD8	HGNC	ENSG00000160111	tier1	-	-	26	0	0.00	32	10	23.81	23	0	0.00	35	6	14.63
IDH3A	0	genome.wustl.edu	37	15	78452504	78452504	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	15	78452504	78452504	C	T	SNP	IDH3A	ENST00000299518	human	ensembl	74_37	+1	known	missense	c.245	p.S82L	0.999	pfam_IsoPropMal-DH-like_dom,tigrfam_Isocitrate_DH_D	pfam_IsoPropMal-DH-like_dom,tigrfam_Isocitrate_DH_D	-	no_errors	IDH3A	HGNC	ENSG00000166411	tier1	-	-	42	0	0.00	24	5	17.24	123	0	0.00	80	31	27.93
C16orf96	0	genome.wustl.edu	37	16	4624985	4624985	+	Missense_Mutation	SNP	A	A	T			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	16	4624985	4624985	A	T	SNP	C16orf96	ENST00000444310	human	ensembl	74_37	+1	known	missense	c.619	p.N207Y	0.709	NULL	NULL	-	no_errors	C16orf96	HGNC	ENSG00000205832	tier1	-	-	36	0	0.00	16	7	30.43	154	0	0.00	71	13	15.48
ATP8A2	0	genome.wustl.edu	37	13	26043135	26043135	+	Missense_Mutation	SNP	G	G	T			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	13	26043135	26043135	G	T	SNP	ATP8A2	ENST00000381655	human	ensembl	74_37	+1	known	missense	c.97	p.G33C	1.000	NULL	pfam_ATPase_P-typ_transduc_dom_A,superfamily_HAD-like_dom,superfamily_ATPase_P-typ_cyto_domN,prints_Cation_transp_P_typ_ATPase,tigrfam_ATPase_P-typ_Plipid-transp,tigrfam_Cation_transp_P_typ_ATPase	-	no_errors	ATP8A2	HGNC	ENSG00000132932	tier1	-	-	52	0	0.00	9	11	55.00	80	0	0.00	20	22	52.38
GLP1R	0	genome.wustl.edu	37	6	39040728	39040728	+	Silent	SNP	C	C	T			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	6	39040728	39040728	C	T	SNP	GLP1R	ENST00000373256	human	ensembl	74_37	+1	known	silent	c.600	p.A200	1.000	pfam_GPCR_2_secretin-like,pfscan_GPCR_2-like,prints_GPCR_2_secretin-like	pfam_GPCR_2_secretin-like,pfam_GPCR_2_extracellular_dom,smart_GPCR_2_extracellular_dom,pfscan_GPCR_2_extracellular_dom,pfscan_GPCR_2-like,prints_GPCR_2_GLP1_rcpt,prints_GPCR_2_secretin-like,prints_GPCR_2_GLP1/glucagon_rcpt,prints_GPCR_2_GIP_rcpt	-	no_errors	GLP1R	HGNC	ENSG00000112164	tier1	-	-	53	0	0.00	29	9	23.68	86	0	0.00	60	13	17.81
DOCK6	0	genome.wustl.edu	37	19	11353984	11353984	+	Missense_Mutation	SNP	A	A	C			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	A	A	A	C	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	19	11353984	11353984	A	C	SNP	DOCK6	ENST00000294618	human	ensembl	74_37	-1	known	missense	c.1336	p.F446V	1.000	NULL	pfam_DOCK_C,pfam_DOCK_C/D_N	-	no_errors	DOCK6	HGNC	ENSG00000130158	tier1	-	-	127	0	0.00	123	16	11.51	50	0	0.00	42	7	14.29
SRPK2	0	genome.wustl.edu	37	7	104844172	104844172	+	Silent	SNP	T	T	A			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	7	104844172	104844172	T	A	SNP	SRPK2	ENST00000393651	human	ensembl	74_37	-1	known	silent	c.132	p.P44	0.570	NULL	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	-	no_errors	SRPK2	HGNC	ENSG00000135250	tier1	-	-	43	0	0.00	40	20	32.79	34	0	0.00	39	15	27.78
NPHP4	0	genome.wustl.edu	37	1	5924040	5924040	+	Silent	SNP	G	G	T			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	1	5924040	5924040	G	T	SNP	NPHP4	ENST00000378156	human	ensembl	74_37	-1	known	silent	c.4050	p.I1350	1.000	NULL	NULL	-	no_errors	NPHP4	HGNC	ENSG00000131697	tier1	-	-	80	0	0.00	57	22	27.85	131	0	0.00	61	24	27.91
PCDHB13	0	genome.wustl.edu	37	5	140594306	140594306	+	Missense_Mutation	SNP	A	A	T			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	5	140594306	140594306	A	T	SNP	PCDHB13	ENST00000341948	human	ensembl	74_37	+1	known	missense	c.611	p.E204V	0.974	pfam_Cadherin,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin	pfam_Cadherin,pfam_Cadherin_N,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin,prints_Cadherin	-	no_errors	PCDHB13	HGNC	ENSG00000187372	tier1	-	-	70	0	0.00	58	19	24.68	78	0	0.00	58	10	14.71
TSPAN7	0	genome.wustl.edu	37	X	38482210	38482210	+	Nonstop_Mutation	SNP	T	T	A			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	X	38482210	38482210	T	A	SNP	TSPAN7	ENST00000475216	human	ensembl	74_37	+1	known	nonstop	c.136	p.*46K	0.000	NULL	NULL	-	no_errors	TSPAN7	HGNC	ENSG00000156298	tier1	-	-	57	0	0.00	47	7	12.96	129	0	0.00	123	21	14.58
CYP3A4	0	genome.wustl.edu	37	7	99355784	99355784	+	Nonsense_Mutation	SNP	G	G	T			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	7	99355784	99355784	G	T	SNP	CYP3A4	ENST00000336411	human	ensembl	74_37	-1	known	nonsense	c.1484	p.S495*	0.000	superfamily_Cyt_P450	pfam_Cyt_P450,superfamily_Cyt_P450,prints_Cyt_P450_E_CYP3A,prints_Cyt_P450_E_grp-I,prints_Cyt_P450_E_grp-II,prints_Cyt_P450_E_grp-IV,prints_Cyt_P450,prints_Cyt_P450_B	-	no_errors	CYP3A4	HGNC	ENSG00000160868	tier1	-	-	39	0	0.00	55	7	11.29	45	0	0.00	40	9	18.37
TUBA4A	0	genome.wustl.edu	37	2	220115874	220115874	+	Missense_Mutation	SNP	C	C	G			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	2	220115874	220115874	C	G	SNP	TUBA4A	ENST00000248437	human	ensembl	74_37	-1	known	missense	c.547	p.E183Q	1.000	pfam_Tubulin_FtsZ_GTPase,superfamily_Tubulin_FtsZ_GTPase,smart_Tubulin_FtsZ_GTPase,prints_Tubulin,prints_Epsilon_tubulin	pfam_Tubulin_FtsZ_GTPase,pfam_Tubulin/FtsZ_2-layer-sand-dom,superfamily_Tubulin_FtsZ_GTPase,superfamily_Tub_FtsZ_C,smart_Tubulin_FtsZ_GTPase,smart_Tubulin/FtsZ_2-layer-sand-dom,prints_Alpha_tubulin,prints_Tubulin,prints_Epsilon_tubulin,prints_Beta_tubulin,prints_Delta_tubulin	-	no_errors	TUBA4A	HGNC	ENSG00000127824	tier1	-	-	75	0	0.00	36	13	26.53	23	0	0.00	19	4	17.39
BOD1	0	genome.wustl.edu	37	5	173036274	173036274	+	Missense_Mutation	SNP	C	C	A			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	5	173036274	173036274	C	A	SNP	BOD1	ENST00000311086	human	ensembl	74_37	-1	known	missense	c.526	p.D176Y	1.000	NULL	NULL	-	no_errors	BOD1	HGNC	ENSG00000145919	tier1	-	-	78	0	0.00	66	16	19.51	64	1	1.54	48	16	25.00
ENSG00000248115	0	genome.wustl.edu	37	4	53822220	53822220	+	R	SNP	T	T	C			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	4	53822220	53822220	T	C	SNP	ENSG00000248115	ENST00000508813	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	RP11-752D24.2	Clone_based_vega_gene	ENSG00000248115	tier1	-	-	44	0	0.00	33	14	29.79	121	0	0.00	73	25	25.51
MROH2B	0	genome.wustl.edu	37	5	41005734	41005734	+	Missense_Mutation	SNP	A	A	T			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	5	41005734	41005734	A	T	SNP	MROH2B	ENST00000399564	human	ensembl	74_37	-1	known	missense	c.3763	p.W1255R	0.999	superfamily_ARM-type_fold	superfamily_ARM-type_fold	-	no_errors	MROH2B	HGNC	ENSG00000171495	tier1	-	-	72	0	0.00	59	14	19.18	128	0	0.00	82	23	21.70
LOC285556	0	genome.wustl.edu	37	4	100574194	100574194	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	4	100574194	100574194	C	T	SNP	LOC285556	ENST00000511828	human	ensembl	74_37	-1	putative	missense	c.1612	p.A538T	1.000	NULL	NULL	-	no_errors	RP11-766F14.2	Clone_based_vega_gene	ENSG00000248713	tier1	-	-	55	0	0.00	13	33	71.74	57	1	1.72	17	28	62.22
PKHD1	0	genome.wustl.edu	37	6	51612752	51612752	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	6	51612752	51612752	G	A	SNP	PKHD1	ENST00000371117	human	ensembl	74_37	-1	known	missense	c.9662	p.P3221L	0.988	NULL	pfam_IPT,pfam_G8_domain,superfamily_Ig_E-set,superfamily_Pectin_lyase_fold/virulence,smart_IPT,smart_PbH1	-	no_errors	PKHD1	HGNC	ENSG00000170927	tier1	rs145141656	GMAF=0.0005	43	0	0.00	28	18	39.13	132	0	0.00	64	22	25.58
KRT6A	0	genome.wustl.edu	37	12	52886582	52886582	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	12	52886582	52886582	G	A	SNP	KRT6A	ENST00000330722	human	ensembl	74_37	-1	known	missense	c.391	p.P131S	1.000	NULL	pfam_IF,superfamily_Prefoldin,prints_Keratin_II	-	no_errors	KRT6A	HGNC	ENSG00000205420	tier1	-	-	100	0	0.00	84	15	15.15	29	0	0.00	11	6	35.29
SLC25A48	0	genome.wustl.edu	37	5	135188365	135188365	+	Silent	SNP	C	C	T			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	5	135188365	135188365	C	T	SNP	SLC25A48	ENST00000420621	human	ensembl	74_37	+1	known	silent	c.276	p.C92	0.862	superfamily_Mt_carrier_dom	pfam_Mitochondrial_sb/sol_carrier,superfamily_Mt_carrier_dom,pfscan_Mitochondrial_sb/sol_carrier,prints_Mit_carrier	-	no_errors	SLC25A48	HGNC	ENSG00000145832	tier1	-	-	38	0	0.00	19	19	50.00	86	0	0.00	32	37	52.86
SCN2A	0	genome.wustl.edu	37	2	166168534	166168534	+	Splice_Site	SNP	G	G	T			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	2	166168534	166168534	G	T	SNP	SCN2A	ENST00000283256	human	ensembl	74_37	+1	known	splice_site	c.971-1	e7-1	1.000	-	-	-	no_errors	SCN2A	HGNC	ENSG00000136531	tier1	-	-	35	0	0.00	25	6	19.35	88	0	0.00	35	6	14.63
DOCK8	0	genome.wustl.edu	37	9	421060	421060	+	Missense_Mutation	SNP	A	A	T			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	9	421060	421060	A	T	SNP	DOCK8	ENST00000453981	human	ensembl	74_37	+1	known	missense	c.4135	p.M1379L	1.000	NULL	pfam_DOCK_C,pfam_DOCK_C/D_N,superfamily_ARM-type_fold	-	no_errors	DOCK8	HGNC	ENSG00000107099	tier1	-	-	66	0	0.00	35	14	28.57	54	0	0.00	22	10	31.25
MED12L	0	genome.wustl.edu	37	3	151107922	151107922	+	Silent	SNP	A	A	G			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	3	151107922	151107922	A	G	SNP	MED12L	ENST00000474524	human	ensembl	74_37	+1	known	silent	c.5502	p.P1834	1.000	pfam_Mediator_Med12_catenin-bd	pfam_Mediator_Med12_LCEWAV,pfam_Mediator_Med12,pfam_Mediator_Med12_catenin-bd	-	no_errors	MED12L	HGNC	ENSG00000144893	tier1	-	-	57	0	0.00	49	22	30.99	107	0	0.00	73	27	27.00
POF1B	0	genome.wustl.edu	37	X	84560869	84560869	+	Missense_Mutation	SNP	C	C	A			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	X	84560869	84560869	C	A	SNP	POF1B	ENST00000373145	human	ensembl	74_37	-1	known	missense	c.1365	p.E455D	0.999	NULL	NULL	-	no_errors	POF1B	HGNC	ENSG00000124429	tier1	-	-	51	0	0.00	26	8	23.53	125	0	0.00	49	12	19.67
PAGE3	0	genome.wustl.edu	37	X	55287001	55287001	+	Silent	SNP	C	C	A			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	X	55287001	55287001	C	A	SNP	PAGE3	ENST00000374951	human	ensembl	74_37	-1	known	silent	c.285	p.L95	0.000	pfam_GAGE	pfam_GAGE	-	no_errors	PAGE3	HGNC	ENSG00000204279	tier1	-	-	246	0	0.00	240	77	24.29	113	0	0.00	88	34	27.87
BTBD11	0	genome.wustl.edu	37	12	108051405	108051405	+	Silent	SNP	C	C	A			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	12	108051405	108051405	C	A	SNP	BTBD11	ENST00000280758	human	ensembl	74_37	+1	known	silent	c.3225	p.T1075	0.470	NULL	pfam_Ankyrin_rpt,pfam_BTB_POZ,superfamily_BTB/POZ_fold,superfamily_Ankyrin_rpt-contain_dom,superfamily_Histone-fold,smart_Ankyrin_rpt,smart_BTB/POZ-like,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,pfscan_BTB/POZ-like	-	no_errors	BTBD11	HGNC	ENSG00000151136	tier1	-	-	56	0	0.00	30	20	39.22	128	0	0.00	57	23	28.75
OR2J3	0	genome.wustl.edu	37	6	29080202	29080202	+	Missense_Mutation	SNP	C	C	A			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	6	29080202	29080202	C	A	SNP	OR2J3	ENST00000377169	human	ensembl	74_37	+1	known	missense	c.535	p.H179N	0.024	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR2J3	HGNC	ENSG00000204701	tier1	-	-	65	0	0.00	57	7	10.94	86	0	0.00	58	12	17.14
IDH3A	0	genome.wustl.edu	37	15	78452499	78452499	+	Silent	SNP	C	C	T			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	15	78452499	78452499	C	T	SNP	IDH3A	ENST00000299518	human	ensembl	74_37	+1	known	silent	c.240	p.I80	1.000	pfam_IsoPropMal-DH-like_dom,tigrfam_Isocitrate_DH_D	pfam_IsoPropMal-DH-like_dom,tigrfam_Isocitrate_DH_D	-	no_errors	IDH3A	HGNC	ENSG00000166411	tier1	-	-	42	0	0.00	26	5	16.13	119	0	0.00	83	32	27.83
ADAM29	0	genome.wustl.edu	37	4	175898452	175898452	+	Silent	SNP	A	A	G			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	4	175898452	175898452	A	G	SNP	ADAM29	ENST00000359240	human	ensembl	74_37	+1	known	silent	c.1776	p.G592	0.032	pfam_ADAM_Cys-rich,smart_ADAM_Cys-rich	pfam_Peptidase_M12B,pfam_ADAM_Cys-rich,pfam_Peptidase_M12B_N,pfam_Blood-coag_inhib_Disintegrin,superfamily_Blood-coag_inhib_Disintegrin,smart_Blood-coag_inhib_Disintegrin,smart_ADAM_Cys-rich,pfscan_Blood-coag_inhib_Disintegrin,pfscan_Peptidase_M12B,prints_Blood-coag_inhib_Disintegrin	-	no_errors	ADAM29	HGNC	ENSG00000168594	tier1	-	-	47	0	0.00	27	9	25.00	144	0	0.00	67	36	34.95
NOA1	0	genome.wustl.edu	37	4	57832838	57832838	+	Missense_Mutation	SNP	A	A	G			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	4	57832838	57832838	A	G	SNP	NOA1	ENST00000264230	human	ensembl	74_37	-1	known	missense	c.1712	p.L571S	0.996	NULL	superfamily_P-loop_NTPase	-	no_errors	NOA1	HGNC	ENSG00000084092	tier1	-	-	35	0	0.00	8	20	71.43	105	0	0.00	28	54	65.85
FBXO40	0	genome.wustl.edu	37	3	121340749	121340749	+	Missense_Mutation	SNP	C	C	A			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	3	121340749	121340749	C	A	SNP	FBXO40	ENST00000338040	human	ensembl	74_37	+1	known	missense	c.473	p.P158Q	0.001	NULL	superfamily_F-box_dom,superfamily_TRAF-like,pfscan_F-box_dom,pfscan_Znf_TRAF	-	no_errors	FBXO40	HGNC	ENSG00000163833	tier1	-	-	29	0	0.00	20	8	28.57	174	1	0.57	87	34	28.10
OR13G1	0	genome.wustl.edu	37	1	247836034	247836034	+	Missense_Mutation	SNP	A	A	T			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	1	247836034	247836034	A	T	SNP	OR13G1	ENST00000359688	human	ensembl	74_37	-1	known	missense	c.310	p.S104T	0.390	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,prints_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,prints_Olfact_rcpt,prints_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM	-	no_errors	OR13G1	HGNC	ENSG00000197437	tier1	-	-	45	0	0.00	24	3	11.11	105	0	0.00	43	7	14.00
CAMK2B	0	genome.wustl.edu	37	7	44294196	44294196	+	Missense_Mutation	SNP	C	C	A			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	7	44294196	44294196	C	A	SNP	CAMK2B	ENST00000395749	human	ensembl	74_37	-1	known	missense	c.286	p.G96W	1.000	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	pfam_Prot_kinase_dom,pfam_Ca/CaM-dep_prot_kinase-assoc,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	-	no_errors	CAMK2B	HGNC	ENSG00000058404	tier1	-	-	47	0	0.00	52	13	20.00	60	0	0.00	72	14	16.28
HDC	0	genome.wustl.edu	37	15	50534992	50534992	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	15	50534992	50534992	G	A	SNP	HDC	ENST00000267845	human	ensembl	74_37	-1	known	missense	c.1454	p.P485L	0.924	NULL	pfam_PyrdxlP-dep_de-COase,superfamily_PyrdxlP-dep_Trfase,prints_Aromatic_deC	-	no_errors	HDC	HGNC	ENSG00000140287	tier1	-	-	42	0	0.00	14	12	46.15	90	0	0.00	27	26	49.06
LOC285556	0	genome.wustl.edu	37	4	100575157	100575157	+	Missense_Mutation	SNP	G	G	T			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	4	100575157	100575157	G	T	SNP	LOC285556	ENST00000511828	human	ensembl	74_37	-1	putative	missense	c.649	p.H217N	0.000	NULL	NULL	-	no_errors	RP11-766F14.2	Clone_based_vega_gene	ENSG00000248713	tier1	-	-	39	0	0.00	19	5	20.83	92	0	0.00	50	18	26.47
CD1C	0	genome.wustl.edu	37	1	158261127	158261127	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	1	158261127	158261127	C	T	SNP	CD1C	ENST00000368170	human	ensembl	74_37	+1	known	missense	c.265	p.R89C	0.000	superfamily_MHC_I/II-like_Ag-recog	pfam_Ig_C1-set,superfamily_MHC_I/II-like_Ag-recog,smart_Ig_C1-set,pfscan_Ig-like_dom	-	no_errors	CD1C	HGNC	ENSG00000158481	tier1	rs145638725	-	62	0	0.00	14	25	64.10	129	0	0.00	31	45	58.44
WNK3	0	genome.wustl.edu	37	X	54263641	54263641	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	X	54263641	54263641	G	A	SNP	WNK3	ENST00000354646	human	ensembl	74_37	-1	known	missense	c.4358	p.S1453F	0.000	NULL	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Kinase_OSR1/WNK_CCT,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	-	no_errors	WNK3	HGNC	ENSG00000196632	tier1	-	-	61	0	0.00	36	37	50.68	77	0	0.00	36	39	51.32
FABP1	0	genome.wustl.edu	37	2	88427556	88427556	+	R	SNP	C	C	G			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	2	88427556	88427556	C	G	SNP	FABP1	ENST00000495375	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	FABP1	HGNC	ENSG00000163586	tier1	-	-	43	0	0.00	32	13	28.89	69	0	0.00	38	14	26.92
ENSG00000268032	0	genome.wustl.edu	37	19	18142570	18142570	+	R	SNP	G	G	T			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	19	18142570	18142570	G	T	SNP	ENSG00000268032	ENST00000594957	human	ensembl	74_37	+1	known	rna	NULL	NULL	1.000	-	-	-	no_errors	CTB-52I2.4	Clone_based_vega_gene	ENSG00000268032	tier1	-	-	36	0	0.00	55	13	19.12	107	0	0.00	136	31	18.56
ASPHD2	0	genome.wustl.edu	37	22	26839163	26839163	+	Silent	SNP	G	G	T			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	22	26839163	26839163	G	T	SNP	ASPHD2	ENST00000215906	human	ensembl	74_37	+1	known	silent	c.1101	p.P367	0.006	NULL	pfam_Asp_Arg_b-Hydrxlase	-	no_errors	ASPHD2	HGNC	ENSG00000128203	tier1	-	-	36	0	0.00	30	5	14.29	105	0	0.00	65	11	14.47
HNRNPM	0	genome.wustl.edu	37	19	8553897	8553897	+	R	SNP	G	G	C			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	19	8553897	8553897	G	C	SNP	HNRNPM	ENST00000602219	human	ensembl	74_37	+1	known	rna	NULL	NULL	1.000	-	-	-	no_errors	HNRNPM	HGNC	ENSG00000099783	tier1	-	-	82	0	0.00	81	15	15.62	116	0	0.00	118	26	17.81
FAM186B	0	genome.wustl.edu	37	12	49993263	49993263	+	Silent	SNP	G	G	C			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	12	49993263	49993263	G	C	SNP	FAM186B	ENST00000257894	human	ensembl	74_37	-1	known	silent	c.2160	p.L720	0.996	NULL	NULL	-	no_errors	FAM186B	HGNC	ENSG00000135436	tier1	-	-	53	0	0.00	42	6	12.50	107	0	0.00	39	19	32.76
ATRX	0	genome.wustl.edu	37	X	76909587	76909587	+	Splice_Site	SNP	C	C	T			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	X	76909587	76909587	C	T	SNP	ATRX	ENST00000373344	human	ensembl	74_37	-1	known	splice_site	c.4317+1	e14+1	1.000	-	-	-	no_errors	ATRX	HGNC	ENSG00000085224	tier1	-	-	33	0	0.00	10	16	61.54	170	0	0.00	34	69	66.99
TENM4	0	genome.wustl.edu	37	11	78497988	78497988	+	Nonsense_Mutation	SNP	T	T	A			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	11	78497988	78497988	T	A	SNP	TENM4	ENST00000278550	human	ensembl	74_37	-1	known	nonsense	c.2320	p.K774*	1.000	pfam_EGF_extracell,smart_EG-like_dom,pfscan_EG-like_dom	pfam_Ten_N,pfam_EGF_extracell,pfam_YD,superfamily_CarboxyPept-like_regulatory,smart_EG-like_dom,pfscan_EG-like_dom,tigrfam_YD,tigrfam_Rhs_assc_core	-	no_errors	TENM4	HGNC	ENSG00000149256	tier1	-	-	78	0	0.00	51	16	23.88	16	0	0.00	12	2	14.29
BMS1P8	0	genome.wustl.edu	37	16	33490022	33490022	+	R	SNP	G	G	T			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	16	33490022	33490022	G	T	SNP	BMS1P8	ENST00000567036	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.990	-	-	-	no_errors	BMS1P8	HGNC	ENSG00000260518	tier1	-	-	17	0	0.00	14	5	26.32	113	0	0.00	84	12	12.50
ZNF85	0	genome.wustl.edu	37	19	21131580	21131580	+	Missense_Mutation	SNP	G	G	T			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	19	21131580	21131580	G	T	SNP	ZNF85	ENST00000328178	human	ensembl	74_37	+1	known	missense	c.260	p.W87L	0.001	NULL	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF85	HGNC	ENSG00000105750	tier1	-	-	50	0	0.00	75	8	9.64	40	0	0.00	51	7	12.07
MUC17	0	genome.wustl.edu	37	7	100679631	100679631	+	Missense_Mutation	SNP	G	G	T			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	7	100679631	100679631	G	T	SNP	MUC17	ENST00000306151	human	ensembl	74_37	+1	known	missense	c.4934	p.S1645I	0.000	NULL	pfam_SEA_dom,smart_SEA_dom,pfscan_EG-like_dom,pfscan_SEA_dom	-	no_errors	MUC17	HGNC	ENSG00000169876	tier1	-	-	81	0	0.00	82	21	20.39	29	0	0.00	28	5	15.15
RGN	0	genome.wustl.edu	37	X	46952420	46952420	+	R	SNP	G	G	T			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	X	46952420	46952420	G	T	SNP	RGN	ENST00000475448	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.019	-	-	-	no_errors	RGN	HGNC	ENSG00000130988	tier1	-	-	76	0	0.00	74	14	15.91	134	0	0.00	80	30	27.27
LPAR3	0	genome.wustl.edu	37	1	85331339	85331339	+	Silent	SNP	G	G	A			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	1	85331339	85331339	G	A	SNP	LPAR3	ENST00000370611	human	ensembl	74_37	-1	known	silent	c.465	p.I155	0.583	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_GPCR_Rhodpsn	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_LPA_rcpt_EDG7,prints_GPCR_Rhodpsn,prints_LPA_rcpt,prints_LPA_rcpt_EDG2,prints_Melcrt_ACTH_rcpt	-	no_errors	LPAR3	HGNC	ENSG00000171517	tier1	-	-	35	0	0.00	33	10	23.26	121	1	0.82	38	23	37.70
CCDC144CP	0	genome.wustl.edu	37	17	20239613	20239613	+	R	SNP	G	G	T			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	17	20239613	20239613	G	T	SNP	CCDC144CP	ENST00000340196	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.002	-	-	-	no_errors	CCDC144CP	HGNC	ENSG00000154898	tier1	-	-	13	0	0.00	7	4	36.36	31	0	0.00	18	6	25.00
SPEF2	0	genome.wustl.edu	37	5	35700617	35700617	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	5	35700617	35700617	G	A	SNP	SPEF2	ENST00000356031	human	ensembl	74_37	+1	known	missense	c.2161	p.D721N	0.819	pfam_Adenylate_kin,superfamily_P-loop_NTPase	pfam_DUF1042,pfam_Adenylate_kin,pfam_HATC_dom_C,superfamily_P-loop_NTPase,superfamily_CH-domain,pfscan_CH-domain	-	no_errors	SPEF2	HGNC	ENSG00000152582	tier1	-	-	25	0	0.00	26	11	29.73	108	0	0.00	65	23	26.14
SCN9A	0	genome.wustl.edu	37	2	167085227	167085227	+	Missense_Mutation	SNP	G	G	T			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	2	167085227	167085227	G	T	SNP	SCN9A	ENST00000303354	human	ensembl	74_37	-1	known	missense	c.4183	p.L1395I	0.994	pfam_Ion_trans_dom	pfam_Ion_trans_dom,pfam_DUF3451,pfam_Na_trans_assoc,pfam_PKD1_2_channel,smart_IQ_motif_EF-hand-BS,prints_Na_channel_asu,prints_PKD_2	-	no_errors	SCN9A	HGNC	ENSG00000169432	tier1	-	-	57	0	0.00	9	21	70.00	158	0	0.00	40	34	45.95
ADAM22	0	genome.wustl.edu	37	7	87774475	87774475	+	Silent	SNP	T	T	A			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	7	87774475	87774475	T	A	SNP	ADAM22	ENST00000265727	human	ensembl	74_37	+1	known	silent	c.1356	p.I452	1.000	pfscan_Blood-coag_inhib_Disintegrin	pfam_Peptidase_M12B,pfam_Peptidase_M12B_N,pfam_ADAM_Cys-rich,pfam_Blood-coag_inhib_Disintegrin,superfamily_Blood-coag_inhib_Disintegrin,smart_Blood-coag_inhib_Disintegrin,smart_ADAM_Cys-rich,pfscan_Blood-coag_inhib_Disintegrin,pfscan_Peptidase_M12B,prints_Blood-coag_inhib_Disintegrin	-	no_errors	ADAM22	HGNC	ENSG00000008277	tier1	-	-	69	0	0.00	83	18	17.82	97	0	0.00	72	20	21.74
DCC	0	genome.wustl.edu	37	18	50985690	50985690	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	18	50985690	50985690	G	A	SNP	DCC	ENST00000442544	human	ensembl	74_37	+1	known	missense	c.3481	p.E1161K	1.000	pfam_Neogenin_C	pfam_Neogenin_C,pfam_Fibronectin_type3,pfam_Ig_I-set,pfam_Ig_V-set,pfam_Immunoglobulin,superfamily_Fibronectin_type3,smart_Ig_sub,smart_Ig_sub2,smart_Fibronectin_type3,pfscan_Fibronectin_type3,pfscan_Ig-like_dom	-	no_errors	DCC	HGNC	ENSG00000187323	tier1	-	-	40	0	0.00	27	9	25.00	108	0	0.00	47	31	39.74
GMFG	0	genome.wustl.edu	37	19	39819656	39819656	+	Missense_Mutation	SNP	G	G	C			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	19	39819656	39819656	G	C	SNP	GMFG	ENST00000597595	human	ensembl	74_37	-1	known	missense	c.341	p.T114R	0.996	pfam_Actin-bd_cofilin/tropomyosin,smart_Actin-bd_cofilin/tropomyosin,pirsf_GMF-beta	pfam_Actin-bd_cofilin/tropomyosin,smart_Actin-bd_cofilin/tropomyosin,pirsf_GMF-beta	-	no_errors	GMFG	HGNC	ENSG00000130755	tier1	-	-	41	0	0.00	41	6	12.77	112	0	0.00	100	14	12.28
DRD3	0	genome.wustl.edu	37	3	113850079	113850079	+	Missense_Mutation	SNP	C	C	A			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	3	113850079	113850079	C	A	SNP	DRD3	ENST00000383673	human	ensembl	74_37	-1	known	missense	c.892	p.V298F	1.000	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Dopamine_D3_rcpt	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfam_7TM_GPCR_serpentine_rcpt_Srx,pfscan_GPCR_Rhodpsn_7TM,prints_Dopamine_D3_rcpt,prints_GPCR_Rhodpsn,prints_Dopamine_rcpt	-	no_errors	DRD3	HGNC	ENSG00000151577	tier1	-	-	86	0	0.00	34	11	24.44	140	0	0.00	69	21	23.33
ACRBP	0	genome.wustl.edu	37	12	6753720	6753720	+	Missense_Mutation	SNP	A	A	C			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	A	A	A	C	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	12	6753720	6753720	A	C	SNP	ACRBP	ENST00000229243	human	ensembl	74_37	-1	known	missense	c.527	p.V176G	0.979	pfam_Proacrosin-bd	pfam_Proacrosin-bd	-	no_errors	ACRBP	HGNC	ENSG00000111644	tier1	-	-	55	0	0.00	11	29	72.50	54	0	0.00	18	34	65.38
SPHKAP	0	genome.wustl.edu	37	2	228883837	228883837	+	Missense_Mutation	SNP	T	T	C			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	2	228883837	228883837	T	C	SNP	SPHKAP	ENST00000392056	human	ensembl	74_37	-1	known	missense	c.1733	p.E578G	0.995	NULL	pfam_AKAP_110_C	-	no_errors	SPHKAP	HGNC	ENSG00000153820	tier1	-	-	27	0	0.00	16	7	30.43	61	0	0.00	28	8	22.22
CAC1B	0	genome.wustl.edu	37	9	140852096	140852096	+	Silent	SNP	C	C	T			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	9	140852096	140852096	C	T	SNP	CAC1B	ENST00000371355	human	ensembl	74_37	+1	known	silent	c.1293	p.H431	0.995	NULL	pfam_Ion_trans_dom,pfam_VDCC_a1su_IQ,pfam_PKD1_2_channel,pfscan_EF_hand_dom,prints_VDCCAlpha1,prints_VDCC_N_a1su,prints_PKD_2	-	no_errors	CAC1B	HGNC	ENSG00000148408	tier1	-	-	20	0	0.00	4	16	80.00	68	1	1.45	17	29	63.04
OR1L1	0	genome.wustl.edu	37	9	125424787	125424787	+	Missense_Mutation	SNP	A	A	T			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	9	125424787	125424787	A	T	SNP	OR1L1	ENST00000373686	human	ensembl	74_37	+1	known	missense	c.943	p.N315Y	0.000	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR1L1	HGNC	ENSG00000173679	tier1	-	-	34	0	0.00	15	17	53.12	119	0	0.00	34	53	60.92
ZNF343	0	genome.wustl.edu	37	20	2473378	2473378	+	Missense_Mutation	SNP	T	T	A			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	20	2473378	2473378	T	A	SNP	ZNF343	ENST00000278772	human	ensembl	74_37	-1	known	missense	c.271	p.M91L	0.468	pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,pfscan_Krueppel-associated_box	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF343	HGNC	ENSG00000088876	tier1	-	-	49	0	0.00	34	14	29.17	105	0	0.00	54	27	32.93
SNRPE	0	genome.wustl.edu	37	1	203830841	203830841	+	Missense_Mutation	SNP	C	C	G			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	1	203830841	203830841	C	G	SNP	SNRPE	ENST00000414487	human	ensembl	74_37	+1	known	missense	c.54	p.I18M	1.000	superfamily_LSM_dom	pfam_Ribonucl_LSM,superfamily_LSM_dom,smart_Ribonucl_LSM_euk/arc	-	no_errors	SNRPE	HGNC	ENSG00000182004	tier1	-	-	46	0	0.00	9	30	76.92	116	0	0.00	18	41	69.49
PIK3CB	0	genome.wustl.edu	37	3	138478102	138478102	+	Silent	SNP	G	G	C			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	3	138478102	138478102	G	C	SNP	PIK3CB	ENST00000289153	human	ensembl	74_37	-1	known	silent	c.84	p.G28	1.000	NULL	pfam_PInositide-3_kin_accessory_dom,pfam_PI3/4_kinase_cat_dom,pfam_PI3K_adapt-bd_dom,pfam_PI3K_Ras-bd_dom,pfam_PI3K_C2_dom,superfamily_Kinase-like_dom,superfamily_C2_dom,superfamily_ARM-type_fold,smart_PI3K_adapt-bd_dom,smart_PI3K_Ras-bd_dom,smart_PI3K_C2_dom,smart_PInositide-3_kin_accessory_dom,smart_PI3/4_kinase_cat_dom,pfscan_PI3/4_kinase_cat_dom	-	no_errors	PIK3CB	HGNC	ENSG00000051382	tier1	-	-	40	0	0.00	16	13	44.83	122	0	0.00	74	15	16.85
PHKA1	0	genome.wustl.edu	37	X	71800880	71800880	+	Missense_Mutation	SNP	A	A	C			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	A	A	A	C	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	X	71800880	71800880	A	C	SNP	PHKA1	ENST00000373539	human	ensembl	74_37	-1	known	missense	c.3695	p.L1232R	1.000	NULL	pfam_Glyco_hydro_15,superfamily_6-hairpin_glycosidase-like	-	no_errors	PHKA1	HGNC	ENSG00000067177	tier1	-	-	124	0	0.00	112	17	13.18	97	0	0.00	85	13	13.27
NME9	0	genome.wustl.edu	37	3	138037031	138037031	+	Nonsense_Mutation	SNP	T	T	A			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	3	138037031	138037031	T	A	SNP	NME9	ENST00000333911	human	ensembl	74_37	-1	known	nonsense	c.226	p.K76*	0.992	pfam_Thioredoxin_domain,superfamily_Thioredoxin-like_fold	pfam_Nucleoside_diP_kinase,pfam_Thioredoxin_domain,superfamily_Nucleoside_diP_kinase,superfamily_Thioredoxin-like_fold,smart_Nucleoside_diP_kinase,prints_Nucleoside_diP_kinase	-	no_errors	NME9	HGNC	ENSG00000181322	tier1	-	-	39	0	0.00	30	5	14.29	121	0	0.00	76	26	25.49
PCDHAC2	0	genome.wustl.edu	37	5	140348132	140348132	+	Missense_Mutation	SNP	T	T	G			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	T	T	T	G	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	5	140348132	140348132	T	G	SNP	PCDHAC2	ENST00000289269	human	ensembl	74_37	+1	known	missense	c.1781	p.V594G	1.000	superfamily_Cadherin-like,pfscan_Cadherin	pfam_Cadherin,pfam_Cadherin_N,superfamily_Cadherin-like,smart_Cadherin,prints_Cadherin,pfscan_Cadherin	-	no_errors	PCDHAC2	HGNC	ENSG00000243232	tier1	-	-	24	0	0.00	21	6	22.22	140	0	0.00	116	20	14.71
DJC13	0	genome.wustl.edu	37	3	132235548	132235548	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	3	132235548	132235548	G	A	SNP	DJC13	ENST00000260818	human	ensembl	74_37	+1	known	missense	c.5561	p.G1854D	1.000	superfamily_ARM-type_fold	pfam_DnaJ_domain,superfamily_ARM-type_fold,superfamily_GYF,smart_DnaJ_domain,pfscan_DnaJ_domain	-	no_errors	DJC13	HGNC	ENSG00000138246	tier1	-	-	41	0	0.00	28	3	9.68	94	1	1.05	50	16	24.24
PAQR9	0	genome.wustl.edu	37	3	142681480	142681480	+	Silent	SNP	G	G	A			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	3	142681480	142681480	G	A	SNP	PAQR9	ENST00000340634	human	ensembl	74_37	-1	known	silent	c.699	p.T233	0.168	pfam_HlyIII-related	pfam_HlyIII-related	-	no_errors	PAQR9	HGNC	ENSG00000188582	tier1	-	-	31	0	0.00	17	11	39.29	28	0	0.00	22	14	38.89
PMFBP1	0	genome.wustl.edu	37	16	72166711	72166711	+	Silent	SNP	C	C	A			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	16	72166711	72166711	C	A	SNP	PMFBP1	ENST00000537465	human	ensembl	74_37	-1	known	silent	c.1383	p.L461	0.017	NULL	NULL	-	no_errors	PMFBP1	HGNC	ENSG00000118557	tier1	-	-	54	0	0.00	18	12	40.00	65	0	0.00	23	9	28.12
ZNF724P	0	genome.wustl.edu	37	19	23405795	23405795	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	19	23405795	23405795	C	T	SNP	ZNF724P	ENST00000418100	human	ensembl	74_37	-1	novel	missense	c.1252	p.G418R	1.000	pfscan_Znf_C2H2	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF724P	HGNC	ENSG00000196081	tier1	-	-	49	0	0.00	40	11	21.57	36	0	0.00	35	10	22.22
GLTSCR2	0	genome.wustl.edu	37	19	48248837	48248837	+	Silent	SNP	C	C	T			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	19	48248837	48248837	C	T	SNP	GLTSCR2	ENST00000246802	human	ensembl	74_37	+1	known	silent	c.21	p.G7	0.000	pirsf_Gltscr2	pfam_P60-like,pirsf_Gltscr2	-	no_errors	GLTSCR2	HGNC	ENSG00000105373	tier1	-	-	173	0	0.00	81	40	32.79	30	0	0.00	20	11	35.48
PRKXP1	0	genome.wustl.edu	37	15	101088251	101088254	+	R	DEL	AACA	AACA	-			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	AACA	AACA	AACA	-	AACA	AACA	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	15	101088251	101088254	AACA	-	DEL	PRKXP1	ENST00000602585	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.118:0.119:0.119:0.117	-	-	-	no_errors	RP11-526I2.5	Clone_based_vega_gene	ENSG00000270127	tier1			23	0	0.00	8	10	55.56	43	0	0.00	18	18	50.00
IP6K3	0	genome.wustl.edu	37	6	33703226	33703226	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	6	33703226	33703226	C	T	SNP	IP6K3	ENST00000293756	human	ensembl	74_37	-1	known	missense	c.28	p.G10R	0.440	NULL	pfam_IPK	-	no_errors	IP6K3	HGNC	ENSG00000161896	tier1	rs141301327	-	44	0	0.00	16	36	69.23	24	0	0.00	3	20	86.96
LOC101928780	0	genome.wustl.edu	37	19	54628083	54628083	+	R	SNP	C	C	A			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	19	54628083	54628083	C	A	SNP	LOC101928780	ENST00000452097	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.003	-	-	-	no_errors	AC012314.8	Clone_based_vega_gene	ENSG00000237017	tier1	-	-	73	0	0.00	52	15	22.39	20	0	0.00	9	3	25.00
MUC4	0	genome.wustl.edu	37	3	195509808	195509808	+	Silent	SNP	A	A	G			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	3	195509808	195509808	A	G	SNP	MUC4	ENST00000463781	human	ensembl	74_37	-1	known	silent	c.8643	p.L2881	0.086	NULL	pfam_Nidogen_extracell_dom,pfam_AMOP,pfam_VWF_type-D,smart_Nidogen_extracell_dom,smart_AMOP,smart_VWF_type-D,smart_EG-like_dom,pfscan_AMOP,pfscan_EG-like_dom	-	no_errors	MUC4	HGNC	ENSG00000145113	tier1	-	-	219	0	0.00	113	58	33.92	11	0	0.00	9	3	25.00
SYNE1	0	genome.wustl.edu	37	6	152763261	152763261	+	Missense_Mutation	SNP	G	G	T			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	6	152763261	152763261	G	T	SNP	SYNE1	ENST00000265368	human	ensembl	74_37	-1	known	missense	c.3957	p.S1319R	0.774	superfamily_Calpain_domain_III,superfamily_ABC1_TM_dom	pfam_Spectrin_repeat,pfam_CH-domain,pfam_KASH,superfamily_CH-domain,superfamily_Calpain_domain_III,superfamily_ABC1_TM_dom,smart_CH-domain,smart_Spectrin/alpha-actinin,pfscan_CH-domain,pfscan_KASH	-	no_errors	SYNE1	HGNC	ENSG00000131018	tier1	-	-	25	0	0.00	9	7	43.75	8	0	0.00	5	2	28.57
PELO	0	genome.wustl.edu	37	5	52096725	52096725	+	Missense_Mutation	SNP	A	A	T			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	5	52096725	52096725	A	T	SNP	PELO	ENST00000274311	human	ensembl	74_37	+1	known	missense	c.497	p.N166I	1.000	pfam_eRF1_2,tigrfam_Transl_rel_pelota-like	pfam_eRF1_1_Pelota,pfam_eRF1_2,pfam_eRF1_3,tigrfam_Transl_rel_pelota-like	-	no_errors	PELO	HGNC	ENSG00000152684	tier1	-	-	30	0	0.00	18	6	25.00	93	0	0.00	67	7	9.46
CXorf30	0	genome.wustl.edu	37	X	36371692	36371692	+	Missense_Mutation	SNP	T	T	G			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	T	T	T	G	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	X	36371692	36371692	T	G	SNP	CXorf30	ENST00000378657	human	ensembl	74_37	+1	known	missense	c.1085	p.I362S	0.004	NULL	NULL	-	no_errors	CXorf30	HGNC	ENSG00000205081	tier1	-	-	55	0	0.00	55	12	17.91	128	0	0.00	80	8	9.09
ADAMTS20	0	genome.wustl.edu	37	12	43821218	43821218	+	Nonsense_Mutation	SNP	C	C	A			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	12	43821218	43821218	C	A	SNP	ADAMTS20	ENST00000389420	human	ensembl	74_37	-1	known	nonsense	c.4000	p.E1334*	1.000	pfam_Thrombospondin_1_rpt,superfamily_Thrombospondin_1_rpt,smart_Thrombospondin_1_rpt,pfscan_Thrombospondin_1_rpt	pfam_Pept_M12B_GON-ADAMTSs,pfam_Thrombospondin_1_rpt,pfam_Peptidase_M12B_N,pfam_ADAM_spacer1,pfam_Peptidase_M12B,superfamily_Thrombospondin_1_rpt,smart_Thrombospondin_1_rpt,pfscan_Pept_M12B_GON-ADAMTSs,pfscan_Thrombospondin_1_rpt,pfscan_Peptidase_M12B,prints_Peptidase_M12B_ADAM-TS	-	no_errors	ADAMTS20	HGNC	ENSG00000173157	tier1	-	-	43	0	0.00	37	4	9.76	110	0	0.00	86	4	4.44
SLCO5A1	0	genome.wustl.edu	37	8	70650332	70650332	+	Missense_Mutation	SNP	G	G	T			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	8	70650332	70650332	G	T	SNP	SLCO5A1	ENST00000260126	human	ensembl	74_37	-1	known	missense	c.1366	p.P456T	1.000	pfam_OA_transporter,pfam_MFS,superfamily_MFS_dom_general_subst_transpt,pfscan_MFS_dom,tigrfam_OA_transporter	pfam_OA_transporter,pfam_MFS,pfam_Kazal_dom,superfamily_MFS_dom_general_subst_transpt,pfscan_MFS_dom,tigrfam_OA_transporter	-	no_errors	SLCO5A1	HGNC	ENSG00000137571	tier1	-	-	43	0	0.00	37	5	11.90	165	2	1.20	99	21	17.50
SRPK2	0	genome.wustl.edu	37	7	104844171	104844171	+	Missense_Mutation	SNP	G	G	T			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	7	104844171	104844171	G	T	SNP	SRPK2	ENST00000393651	human	ensembl	74_37	-1	known	missense	c.133	p.P45T	1.000	NULL	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	-	no_errors	SRPK2	HGNC	ENSG00000135250	tier1	-	-	43	0	0.00	41	20	32.79	35	1	2.78	39	15	27.78
OR12D2	0	genome.wustl.edu	37	6	29365079	29365079	+	Silent	SNP	G	G	T			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	6	29365079	29365079	G	T	SNP	OR12D2	ENST00000383555	human	ensembl	74_37	+1	known	silent	c.603	p.T201	0.000	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR12D2	HGNC	ENSG00000168787	tier1	-	-	23	0	0.00	17	11	39.29	95	0	0.00	41	20	32.79
ATXN1	0	genome.wustl.edu	37	6	16327956	16327956	+	Missense_Mutation	SNP	C	C	G			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	6	16327956	16327956	C	G	SNP	ATXN1	ENST00000244769	human	ensembl	74_37	-1	known	missense	c.586	p.E196Q	1.000	NULL	pfam_Ataxin-1_HBP1,pfam_Capicua_tscrpt_rep_mod,superfamily_Ataxin-1_HBP1,smart_Ataxin_AXH_dom,pfscan_Ataxin-1_HBP1	-	no_errors	ATXN1	HGNC	ENSG00000124788	tier1	-	-	37	0	0.00	21	4	14.81	10	0	0.00	3	0	0.00
FAR2	0	genome.wustl.edu	37	12	29449969	29449969	+	Silent	SNP	T	T	C			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	12	29449969	29449969	T	C	SNP	FAR2	ENST00000182377	human	ensembl	74_37	+1	known	silent	c.381	p.L127	0.237	pfam_Male_sterile_D-bd,pfam_Epimerase_deHydtase,pfam_3Beta_OHSteriod_DH/Estase,pfam_Polysac_CapD-like	pfam_Male_sterile_D-bd,pfam_FAR,pfam_Epimerase_deHydtase,pfam_3Beta_OHSteriod_DH/Estase,pfam_Polysac_CapD-like	-	no_errors	FAR2	HGNC	ENSG00000064763	tier1	-	-	31	0	0.00	18	3	14.29	10	0	0.00	4	0	0.00
IPO13	0	genome.wustl.edu	37	1	44415575	44415575	+	Silent	SNP	C	C	A			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	1	44415575	44415575	C	A	SNP	IPO13	ENST00000372343	human	ensembl	74_37	+1	known	silent	c.571	p.R191	1.000	pfam_Exportin-1/Importin-b-like,superfamily_ARM-type_fold	pfam_Exportin-1/Importin-b-like,pfam_Importin-beta_N,superfamily_ARM-type_fold,smart_Importin-beta_N,pfscan_Importin-beta_N	-	no_errors	IPO13	HGNC	ENSG00000117408	tier1	-	-	49	0	0.00	39	12	23.53	9	0	0.00	1	0	0.00
PIEZO1	0	genome.wustl.edu	37	16	88800395	88800395	+	Missense_Mutation	SNP	C	C	G			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	16	88800395	88800395	C	G	SNP	PIEZO1	ENST00000301015	human	ensembl	74_37	-1	novel	missense	c.2248	p.E750Q	0.340	NULL	pfam_Piezo	-	no_errors	PIEZO1	HGNC	ENSG00000103335	tier1	rs202139830	-	43	0	0.00	15	4	21.05	14	0	0.00	1	1	50.00
PLA2G4F	0	genome.wustl.edu	37	15	42448730	42448730	+	Nonsense_Mutation	SNP	C	C	T			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	15	42448730	42448730	C	T	SNP	PLA2G4F	ENST00000397272	human	ensembl	74_37	-1	known	nonsense	c.18	p.W6*	0.933	NULL	pfam_LysoPLipase_cat_dom,pfam_C2_dom,superfamily_Acyl_Trfase/lysoPLipase,superfamily_C2_dom,smart_C2_dom,smart_LysoPLipase_cat_dom,pfscan_C2_dom,pfscan_LysoPLipase_cat_dom	-	no_errors	PLA2G4F	HGNC	ENSG00000168907	tier1	-	-	43	0	0.00	26	4	13.33	11	0	0.00	3	0	0.00
SSPO	0	genome.wustl.edu	37	7	149489488	149489488	+	R	SNP	C	C	A			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	7	149489488	149489488	C	A	SNP	SSPO	ENST00000262089	human	ensembl	74_37	+1	known	rna	NULL	NULL	1.000	-	-	-	no_errors	SSPO	HGNC	ENSG00000197558	tier1	-	-	98	0	0.00	63	18	22.22	6	0	0.00	4	0	0.00
ZNF733P	0	genome.wustl.edu	37	7	62752861	62752861	+	R	SNP	G	G	A			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	7	62752861	62752861	G	A	SNP	ZNF733P	ENST00000331425	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	ZNF733P	HGNC	ENSG00000185037	tier1	-	-	43	0	0.00	48	12	20.00	8	0	0.00	8	0	0.00
GOLGA6L4	0	genome.wustl.edu	37	15	82932257	82932288	+	R	DEL	ACACAAATAAATTTAAACTATAAATTAGAAAC	ACACAAATAAATTTAAACTATAAATTAGAAAC	-			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	ACACAAATAAATTTAAACTATAAATTAGAAAC	ACACAAATAAATTTAAACTATAAATTAGAAAC					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	15	82932257	82932288	ACACAAATAAATTTAAACTATAAATTAGAAAC	-	DEL	GOLGA6L4	ENST00000560844	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.140:0.148:0.154:0.160:0.165:0.169:0.172:0.175:0.177:0.178:0.179:0.179:0.180:0.179:0.135:0.131:0.126:0.121:0.112:0.097:0.077:0.050:0.041:0.040:0.045:0.047:0.048:0.046:0.049:0.052:0.050:0.046	-	-	-	no_errors	RP13-996F3.5	Clone_based_vega_gene	ENSG00000215749	tier1			0	0	0.00	0	0	0.00	0	0	0.00	0	0	0.00
KCNQ4	0	genome.wustl.edu	37	1	41304460	41304460	+	R	SNP	G	G	T			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	1	41304460	41304460	G	T	SNP	KCNQ4	ENST00000506017	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.354	-	-	-	no_errors	KCNQ4	HGNC	ENSG00000117013	tier1	-	-	32	0	0.00	15	11	42.31	3	0	0.00	0	0	0.00
MT-ND6	0	genome.wustl.edu	37	MT	14569	14569	+	Silent	SNP	G	G	A			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	MT	14569	14569	G	A	SNP	MT-ND6	ENST00000361681	human	ensembl	74_37	-1	known	silent	c.105	p.S35	NULL	pfam_DH_UbQ/plastoQ_OxRdtase_su6	pfam_DH_UbQ/plastoQ_OxRdtase_su6	-	no_errors	MT-ND6	HGNC	ENSG00000198695	tier1	-	-	447	1	0.22	103	293	73.99	0	0	0.00	0	0	0.00
OR7E94P	0	genome.wustl.edu	37	4	80508906	80508907	+	R	INS	-	-	AA			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	4	80508906	80508907	-	AA	INS	OR7E94P	ENST00000601375	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.004:0.015	-	-	-	no_errors	OR7E94P	HGNC	ENSG00000249646	tier1			16	0	0.00	15	3	16.67	2	0	0.00	1	0	0.00
SLC22A17	0	genome.wustl.edu	37	14	23822003	23822003	+	R	SNP	C	C	G			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	14	23822003	23822003	C	G	SNP	SLC22A17	ENST00000474057	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.003	-	-	-	no_errors	SLC22A17	HGNC	ENSG00000092096	tier1	-	-	43	0	0.00	10	17	62.96	0	0	0.00	2	0	0.00
TM6SF2	0	genome.wustl.edu	37	19	19384023	19384023	+	Missense_Mutation	SNP	A	A	G			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	19	19384023	19384023	A	G	SNP	TM6SF2	ENST00000389363	human	ensembl	74_37	-1	known	missense	c.2	p.M1T	0.994	NULL	pfam_Transmembrane_6/97	-	no_errors	TM6SF2	HGNC	ENSG00000213996	tier1	-	-	11	0	0.00	11	7	38.89	2	0	0.00	2	0	0.00
TNFRSF1B	0	genome.wustl.edu	37	1	12251943	12251943	+	Silent	SNP	G	G	T			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	1	12251943	12251943	G	T	SNP	TNFRSF1B	ENST00000376259	human	ensembl	74_37	+1	known	silent	c.420	p.L140	0.008	smart_TNFR/NGFR_Cys_rich_reg,pfscan_TNFR/NGFR_Cys_rich_reg	pfam_TNFR/NGFR_Cys_rich_reg,smart_TNFR/NGFR_Cys_rich_reg,pfscan_TNFR/NGFR_Cys_rich_reg,prints_TNFR_1B	-	no_errors	TNFRSF1B	HGNC	ENSG00000028137	tier1	-	-	29	0	0.00	32	4	11.11	1	0	0.00	4	0	0.00
CNOT6	0	genome.wustl.edu	37	5	179921643	179921643	+	R	SNP	C	C	A			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	5	179921643	179921643	C	A	SNP	CNOT6	ENST00000507016	human	ensembl	74_37	+1	putative	rna	NULL	NULL	0.998	-	-	-	no_errors	CNOT6	HGNC	ENSG00000113300	tier1	-	-	22	0	0.00	11	7	38.89	4	0	0.00	4	5	55.56
HIVEP3	0	genome.wustl.edu	37	1	41976281	41976281	+	Silent	SNP	A	A	G			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	1	41976281	41976281	A	G	SNP	HIVEP3	ENST00000247584	human	ensembl	74_37	-1	known	silent	c.7062	p.S2354	0.168	NULL	pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2	-	no_errors	HIVEP3	HGNC	ENSG00000127124	tier1	-	-	48	0	0.00	18	6	25.00	3	0	0.00	5	4	44.44
ZAK	0	genome.wustl.edu	37	2	174085893	174085893	+	Missense_Mutation	SNP	G	G	T			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	2	174085893	174085893	G	T	SNP	ZAK	ENST00000338983	human	ensembl	74_37	+1	known	missense	c.1003	p.A335S	1.000	NULL	pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_kinase_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom,prints_Ser-Thr/Tyr_kinase_cat_dom	-	no_errors	MLTK	Uniprot_gn	ENSG00000091436	tier1	-	-	66	0	0.00	50	5	9.09	83	0	0.00	43	2	4.44
AGGF1	0	genome.wustl.edu	37	5	76358970	76358970	+	Nonsense_Mutation	SNP	A	A	T			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	5	76358970	76358970	A	T	SNP	AGGF1	ENST00000312916	human	ensembl	74_37	+1	known	nonsense	c.2038	p.K680*	1.000	NULL	pfam_FHA_dom,pfam_G_patch_dom,superfamily_SMAD_FHA_domain,smart_FHA_dom,smart_G_patch_dom,pfscan_FHA_dom,pfscan_G_patch_dom	-	no_errors	AGGF1	HGNC	ENSG00000164252	tier1	-	-	29	0	0.00	21	8	27.59	61	0	0.00	33	3	8.33
PLD1	0	genome.wustl.edu	37	3	171455451	171455452	+	Splice_Site	INS	-	-	A			TCGA-DX-A8BT-01A-11D-A37C-09	TCGA-DX-A8BT-10A-01D-A37F-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	68092db5-7dc6-4600-a753-460a962693ac	7e653b4b-2223-4e17-8e5f-6af07a25792d	3	171455451	171455452	-	A	INS	PLD1	ENST00000351298	human	ensembl	74_37	-1	known	splice_site_ins	c.161-3_161-2	e2-2	0.999:0.901	-	-	-	no_errors	PLD1	HGNC	ENSG00000075651	tier1			35	0	0.00	25	4	13.79	66	0	0.00	33	2	5.71