Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	default_gene_name	gene_name_source	 ensembl_gene_id	tier	dbSNP	GMAF	n_ref_count	n_alt_count	normal_vaf	t_ref_count	t_alt_count	tumor_vaf	n_ref_count_val	n_alt_count_val	normal_vaf_val	t_ref_count_val	t_alt_count_val	tumor_vaf_val
TBC1D1	0	genome.wustl.edu	37	4	37904119	37904119	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	4	37904119	37904119	G	A	SNP	TBC1D1	ENST00000261439	human	ensembl	74_37	+1	known	missense	c.403	p.D135N	0.972	smart_PTB/PI_dom	pfam_Rab-GTPase-TBC_dom,pfam_DUF3350,pfam_PTB/PI_dom,superfamily_Rab-GTPase-TBC_dom,smart_PTB/PI_dom,smart_Rab-GTPase-TBC_dom,pfscan_PTB/PI_dom,pfscan_Rab-GTPase-TBC_dom	-	no_errors	TBC1D1	HGNC	ENSG00000065882	tier1	-	-	28	0	0.00	28	5	14.71	121	0	0.00	57	20	25.97
C7orf31	0	genome.wustl.edu	37	7	25191226	25191226	+	Missense_Mutation	SNP	C	C	A			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	7	25191226	25191226	C	A	SNP	C7orf31	ENST00000283905	human	ensembl	74_37	-1	known	missense	c.673	p.V225L	0.241	NULL	NULL	-	no_errors	C7orf31	HGNC	ENSG00000153790	tier1	-	-	214	0	0.00	280	34	10.83	86	0	0.00	97	15	13.39
UBBP4	0	genome.wustl.edu	37	17	21731081	21731081	+	Missense_Mutation	SNP	A	A	G			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	17	21731081	21731081	A	G	SNP	UBBP4	ENST00000578713	human	ensembl	74_37	+1	putative	missense	c.383	p.D128G	1.000	pfam_Ubiquitin_dom,pfam_Rad60/SUMO_like,smart_Ubiquitin_dom,pfscan_Ubiquitin_supergroup,prints_Ubiquitin	pfam_Ubiquitin_dom,pfam_Rad60/SUMO_like,smart_Ubiquitin_dom,pfscan_Ubiquitin_supergroup,prints_Ubiquitin	-	no_errors	UBBP4	HGNC	ENSG00000263563	tier1	-	-	177	0	0.00	143	29	16.86	45	0	0.00	27	7	20.59
RYR3	0	genome.wustl.edu	37	15	34060884	34060884	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	15	34060884	34060884	G	A	SNP	RYR3	ENST00000389232	human	ensembl	74_37	+1	known	missense	c.8731	p.V2911I	1.000	superfamily_ARM-type_fold	pfam_Ryanodine_rcpt,pfam_Ca-rel_channel,pfam_Ryanrecept_TM4-6,pfam_SPRY_rcpt,pfam_Ins145_P3_rcpt,pfam_MIR_motif,pfam_RIH_assoc-dom,pfam_Ion_trans_dom,superfamily_MIR_motif,superfamily_ConA-like_lec_gl_sf,superfamily_4_helix_cytokine-like_core,superfamily_ARM-type_fold,smart_MIR_motif,smart_SPla/RYanodine_receptor_subgr,prints_Ryan_recept,pfscan_B30.2/SPRY,pfscan_EF_hand_dom,pfscan_MIR_motif	-	no_errors	RYR3	HGNC	ENSG00000198838	tier1	-	-	94	0	0.00	70	27	27.84	134	0	0.00	62	8	11.43
MACROD2	0	genome.wustl.edu	37	20	15866410	15866410	+	Silent	SNP	C	C	T			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	20	15866410	15866410	C	T	SNP	MACROD2	ENST00000310348	human	ensembl	74_37	+1	known	silent	c.729	p.D243	1.000	NULL	pfam_Macro_dom,smart_Macro_dom,pfscan_Macro_dom	-	no_errors	MACROD2	HGNC	ENSG00000172264	tier1	-	-	104	0	0.00	120	50	29.41	77	0	0.00	53	21	28.38
EGFL6	0	genome.wustl.edu	37	X	13626473	13626473	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	X	13626473	13626473	C	T	SNP	EGFL6	ENST00000380602	human	ensembl	74_37	+1	known	missense	c.686	p.T229M	0.461	pfam_EGF-like_Ca-bd_dom,pfam_EG-like_dom,smart_EGF-like_Ca-bd_dom,smart_EG-like_dom,pfscan_EG-like_dom	pfam_MAM_dom,pfam_EGF-like_Ca-bd_dom,pfam_EG-like_dom,superfamily_ConA-like_lec_gl_sf,smart_EG-like_dom,smart_EGF-like_Ca-bd_dom,smart_MAM_dom,pfscan_EG-like_dom,pfscan_MAM_dom	-	no_errors	EGFL6	HGNC	ENSG00000198759	tier1	rs199623111	-	98	0	0.00	181	32	15.02	36	0	0.00	44	16	26.67
EFR3A	0	genome.wustl.edu	37	8	132957003	132957003	+	Silent	SNP	G	G	A			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	8	132957003	132957003	G	A	SNP	EFR3A	ENST00000254624	human	ensembl	74_37	+1	known	silent	c.99	p.V33	0.999	NULL	superfamily_ARM-type_fold	-	no_errors	EFR3A	HGNC	ENSG00000132294	tier1	-	-	245	0	0.00	240	63	20.79	76	0	0.00	80	15	15.79
CDSN	0	genome.wustl.edu	37	6	31084477	31084477	+	Missense_Mutation	SNP	A	A	T			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	6	31084477	31084477	A	T	SNP	CDSN	ENST00000376288	human	ensembl	74_37	-1	known	missense	c.915	p.S305R	0.412	NULL	NULL	-	no_errors	CDSN	HGNC	ENSG00000204539	tier1	-	-	44	0	0.00	31	8	20.51	101	0	0.00	36	12	25.00
ZNF17	0	genome.wustl.edu	37	19	57924999	57924999	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	19	57924999	57924999	G	A	SNP	ZNF17	ENST00000307658	human	ensembl	74_37	+1	putative	missense	c.16	p.G6R	0.001	superfamily_Krueppel-associated_box	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF17	HGNC	ENSG00000186272	tier1	-	-	107	1	0.93	129	18	12.24	105	0	0.00	121	19	13.48
CD1A	0	genome.wustl.edu	37	1	158226589	158226589	+	Silent	SNP	C	C	T			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	1	158226589	158226589	C	T	SNP	CD1A	ENST00000289429	human	ensembl	74_37	+1	known	silent	c.618	p.A206	0.984	pfscan_Ig-like_dom	pfam_Ig_C1-set,pfam_MHC_I_a_a1/a2,superfamily_MHC_I/II-like_Ag-recog,smart_Ig_C1-set,pfscan_Ig-like_dom	-	no_errors	CD1A	HGNC	ENSG00000158477	tier1	-	-	101	0	0.00	56	16	22.22	56	0	0.00	33	12	26.67
SLC9A7P1	0	genome.wustl.edu	37	12	98848980	98848980	+	R	SNP	C	C	A			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	12	98848980	98848980	C	A	SNP	SLC9A7P1	ENST00000554295	human	ensembl	74_37	-1	putative	rna	NULL	NULL	0.538	-	-	-	no_errors	SLC9A7P1	HGNC	ENSG00000227825	tier1	-	-	43	0	0.00	36	30	45.45	65	0	0.00	31	34	52.31
LAMA2	0	genome.wustl.edu	37	6	129380936	129380936	+	Silent	SNP	C	C	T			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	6	129380936	129380936	C	T	SNP	LAMA2	ENST00000421865	human	ensembl	74_37	+1	known	silent	c.291	p.H97	1.000	pfam_Laminin_N,superfamily_Galactose-bd-like,smart_Laminin_N,pfscan_Laminin_N	pfam_Laminin_G,pfam_EGF_laminin,pfam_Laminin_N,pfam_Laminin_I,pfam_Laminin_B_type_IV,pfam_Laminin_II,superfamily_ConA-like_lec_gl_sf,superfamily_Galactose-bd-like,superfamily_t-SRE,smart_Laminin_N,smart_EGF_laminin,smart_EG-like_dom,smart_Laminin_B_subgr,smart_Laminin_G,pfscan_Laminin_B_type_IV,pfscan_EGF_laminin,pfscan_Laminin_G,pfscan_Laminin_N	-	no_errors	LAMA2	HGNC	ENSG00000196569	tier1	-	-	120	0	0.00	93	23	19.83	84	0	0.00	30	11	26.83
ANO5	0	genome.wustl.edu	37	11	22283767	22283767	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	11	22283767	22283767	G	A	SNP	ANO5	ENST00000324559	human	ensembl	74_37	+1	known	missense	c.1723	p.V575I	1.000	pfam_Anoctamin	pfam_Anoctamin	-	no_errors	ANO5	HGNC	ENSG00000171714	tier1	-	-	191	0	0.00	145	36	19.89	116	0	0.00	46	8	14.55
DENND2A	0	genome.wustl.edu	37	7	140301490	140301490	+	Missense_Mutation	SNP	T	T	A			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	7	140301490	140301490	T	A	SNP	DENND2A	ENST00000275884	human	ensembl	74_37	-1	known	missense	c.708	p.K236N	0.036	NULL	pfam_DENN_dom,pfam_uDENN_dom,pfam_dDENN_dom,smart_uDENN_dom,smart_DENN_dom,smart_dDENN_dom,pfscan_DENN_dom,pfscan_uDENN_dom,pfscan_dDENN_dom	-	no_errors	DENND2A	HGNC	ENSG00000146966	tier1	-	-	56	0	0.00	62	11	15.07	66	0	0.00	57	11	16.18
UGT3A2	0	genome.wustl.edu	37	5	36049323	36049323	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	5	36049323	36049323	C	T	SNP	UGT3A2	ENST00000282507	human	ensembl	74_37	-1	known	missense	c.511	p.G171S	0.001	pfam_UDP_glucos_trans	pfam_UDP_glucos_trans,pfam_Glyco_trans_28_C	-	no_errors	UGT3A2	HGNC	ENSG00000168671	tier1	-	-	173	0	0.00	178	61	25.52	109	0	0.00	115	23	16.55
MUC17	0	genome.wustl.edu	37	7	100675057	100675057	+	Missense_Mutation	SNP	A	A	T			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	7	100675057	100675057	A	T	SNP	MUC17	ENST00000306151	human	ensembl	74_37	+1	known	missense	c.360	p.E120D	0.015	NULL	pfam_SEA_dom,smart_SEA_dom,pfscan_EG-like_dom,pfscan_SEA_dom	-	no_errors	MUC17	HGNC	ENSG00000169876	tier1	-	-	80	0	0.00	101	25	19.84	146	0	0.00	132	21	13.64
C1QTNF2	0	genome.wustl.edu	37	5	159776711	159776711	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	5	159776711	159776711	G	A	SNP	C1QTNF2	ENST00000393975	human	ensembl	74_37	-1	known	missense	c.457	p.R153C	0.973	pfam_Collagen	pfam_C1q,pfam_Collagen,superfamily_Tumour_necrosis_fac-like_dom,smart_C1q,pfscan_C1q,prints_C1q	-	no_errors	C1QTNF2	HGNC	ENSG00000145861	tier1	-	-	72	0	0.00	115	19	14.18	21	0	0.00	36	8	18.18
E2F5	0	genome.wustl.edu	37	8	86127289	86127289	+	R	SNP	T	T	G			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	T	T	T	G	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	8	86127289	86127289	T	G	SNP	E2F5	ENST00000519128	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.159	-	-	-	no_errors	E2F5	HGNC	ENSG00000133740	tier1	-	-	65	0	0.00	24	15	38.46	56	0	0.00	14	6	30.00
NKX2-2-AS1	0	genome.wustl.edu	37	20	21492156	21492156	+	R	SNP	G	G	A			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	20	21492156	21492156	G	A	SNP	NKX2-2-AS1	ENST00000549659	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.999	-	-	-	no_errors	NKX2-2-AS1	HGNC	ENSG00000258197	tier1	-	-	153	0	0.00	186	36	16.22	85	0	0.00	91	18	16.51
SEZ6L	0	genome.wustl.edu	37	22	26736438	26736438	+	Silent	SNP	C	C	T			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	22	26736438	26736438	C	T	SNP	SEZ6L	ENST00000248933	human	ensembl	74_37	+1	known	silent	c.2052	p.Y684	0.111	pfam_CUB_dom,superfamily_CUB_dom,smart_CUB_dom,pfscan_CUB_dom	pfam_CUB_dom,pfam_Sushi_SCR_CCP,superfamily_CUB_dom,superfamily_Sushi_SCR_CCP,smart_CUB_dom,smart_Sushi_SCR_CCP,pfscan_CUB_dom,pfscan_Sushi_SCR_CCP	-	no_errors	SEZ6L	HGNC	ENSG00000100095	tier1	rs138699202	-	95	0	0.00	74	20	21.28	69	0	0.00	75	17	18.48
TMEM163	0	genome.wustl.edu	37	2	135470828	135470828	+	Silent	SNP	T	T	A			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	2	135470828	135470828	T	A	SNP	TMEM163	ENST00000281924	human	ensembl	74_37	-1	known	silent	c.264	p.A88	0.018	NULL	NULL	-	no_errors	TMEM163	HGNC	ENSG00000152128	tier1	-	-	91	0	0.00	75	7	8.54	98	0	0.00	65	11	14.47
STXBP2	0	genome.wustl.edu	37	19	7711208	7711208	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	19	7711208	7711208	C	T	SNP	STXBP2	ENST00000221283	human	ensembl	74_37	+1	known	missense	c.1430	p.P477L	0.993	pfam_Sec1-like,superfamily_Sec1-like	pfam_Sec1-like,superfamily_Sec1-like	-	no_errors	STXBP2	HGNC	ENSG00000076944	tier1	rs121918540	-	170	0	0.00	217	27	11.07	56	0	0.00	65	13	16.67
SNTG2	0	genome.wustl.edu	37	2	1204841	1204841	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	2	1204841	1204841	G	A	SNP	SNTG2	ENST00000308624	human	ensembl	74_37	+1	known	missense	c.644	p.R215H	1.000	NULL	pfam_PDZ,superfamily_PDZ,smart_PDZ,pfscan_PDZ	-	no_errors	SNTG2	HGNC	ENSG00000172554	tier1	rs202078642	-	44	0	0.00	39	11	22.00	70	0	0.00	35	10	22.22
GRIN1	0	genome.wustl.edu	37	9	140058109	140058109	+	Missense_Mutation	SNP	A	A	G			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	9	140058109	140058109	A	G	SNP	GRIN1	ENST00000371561	human	ensembl	74_37	+1	known	missense	c.2432	p.E811G	1.000	pfam_Iontro_glu_rcpt	pfam_Iontro_glu_rcpt,pfam_ANF_lig-bd_rcpt,pfam_SBP_bac_3,pfam_Glu_rcpt_Glu/Gly-bd,pfam_CaM-bd_C0_NMDA_rcpt_NR1,superfamily_Peripla_BP_I,smart_Iontro_glu_rcpt,smart_Glu_rcpt_Glu/Gly-bd,prints_NMDA_rcpt	-	no_errors	GRIN1	HGNC	ENSG00000176884	tier1	-	-	73	0	0.00	19	68	78.16	107	0	0.00	20	58	73.42
CAPN11	0	genome.wustl.edu	37	6	44137260	44137260	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	6	44137260	44137260	C	T	SNP	CAPN11	ENST00000398776	human	ensembl	74_37	+1	known	missense	c.331	p.R111W	1.000	pfam_Peptidase_C2_calpain_cat,smart_Peptidase_C2_calpain_cat,pfscan_Peptidase_C2_calpain_cat,prints_Calpain_cysteine_protease	pfam_Peptidase_C2_calpain_cat,pfam_Calpain_domain_III,superfamily_Calpain_domain_III,smart_Peptidase_C2_calpain_cat,smart_Calpain_III,smart_EF_hand_dom,pfscan_EF_hand_dom,pfscan_Peptidase_C2_calpain_cat,prints_Calpain_cysteine_protease	-	no_errors	CAPN11	HGNC	ENSG00000137225	tier1	-	-	50	0	0.00	17	38	69.09	133	1	0.75	30	77	71.96
UNC45B	0	genome.wustl.edu	37	17	33475325	33475325	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	17	33475325	33475325	C	T	SNP	UNC45B	ENST00000268876	human	ensembl	74_37	+1	known	missense	c.43	p.R15W	0.584	smart_TPR_repeat,pfscan_TPR_repeat,pfscan_TPR-contain_dom	pfam_UNC-45/Ring3,superfamily_ARM-type_fold,smart_TPR_repeat,smart_Armadillo,pfscan_TPR_repeat,pfscan_TPR-contain_dom	-	no_errors	UNC45B	HGNC	ENSG00000141161	tier1	-	-	142	0	0.00	97	22	18.49	120	0	0.00	79	35	30.70
SYCP2	0	genome.wustl.edu	37	20	58470515	58470515	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	20	58470515	58470515	G	A	SNP	SYCP2	ENST00000357552	human	ensembl	74_37	-1	known	missense	c.1642	p.H548Y	0.000	NULL	NULL	-	no_errors	SYCP2	HGNC	ENSG00000196074	tier1	-	-	107	0	0.00	106	20	15.87	29	0	0.00	10	4	28.57
ACTBL2	0	genome.wustl.edu	37	5	56777651	56777651	+	Missense_Mutation	SNP	T	T	G			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	T	T	T	G	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	5	56777651	56777651	T	G	SNP	ACTBL2	ENST00000423391	human	ensembl	74_37	-1	known	missense	c.884	p.Y295S	1.000	pfam_Actin-related,smart_Actin-related	pfam_Actin-related,smart_Actin-related,prints_Actin-related	-	no_errors	ACTBL2	HGNC	ENSG00000169067	tier1	-	-	51	0	0.00	71	16	18.39	62	0	0.00	78	13	14.13
NIT1	0	genome.wustl.edu	37	1	161089680	161089680	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	1	161089680	161089680	G	A	SNP	NIT1	ENST00000368009	human	ensembl	74_37	+1	known	missense	c.529	p.E177K	1.000	pfam_C-N_Hydrolase,superfamily_C-N_Hydrolase,pfscan_C-N_Hydrolase	pfam_C-N_Hydrolase,superfamily_C-N_Hydrolase,pfscan_C-N_Hydrolase	-	no_errors	NIT1	HGNC	ENSG00000158793	tier1	-	-	141	0	0.00	127	21	14.19	95	0	0.00	73	10	12.05
ZNF729	0	genome.wustl.edu	37	19	22499499	22499499	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	19	22499499	22499499	C	T	SNP	ZNF729	ENST00000601693	human	ensembl	74_37	+1	novel	missense	c.3280	p.H1094Y	0.850	smart_Znf_C2H2-like,pfscan_Znf_C2H2	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF729	HGNC	ENSG00000196350	tier1	-	-	119	0	0.00	171	20	10.47	42	0	0.00	22	11	31.43
EFR3A	0	genome.wustl.edu	37	8	132957097	132957097	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	8	132957097	132957097	G	A	SNP	EFR3A	ENST00000254624	human	ensembl	74_37	+1	known	missense	c.193	p.D65N	1.000	NULL	superfamily_ARM-type_fold	-	no_errors	EFR3A	HGNC	ENSG00000132294	tier1	-	-	220	0	0.00	252	49	16.28	98	0	0.00	85	16	15.84
ZDHHC15	0	genome.wustl.edu	37	X	74649796	74649796	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	X	74649796	74649796	G	A	SNP	ZDHHC15	ENST00000373367	human	ensembl	74_37	-1	known	missense	c.469	p.H157Y	1.000	pfam_Znf_DHHC_palmitoyltrfase,superfamily_Plexin-like_fold,pfscan_Znf_DHHC_palmitoyltrfase	pfam_Znf_DHHC_palmitoyltrfase,superfamily_Plexin-like_fold,pfscan_Znf_DHHC_palmitoyltrfase	-	no_errors	ZDHHC15	HGNC	ENSG00000102383	tier1	-	-	160	0	0.00	275	77	21.81	56	0	0.00	68	17	19.32
GOLGA6L2	0	genome.wustl.edu	37	15	23686793	23686793	+	Missense_Mutation	SNP	G	G	T			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	15	23686793	23686793	G	T	SNP	GOLGA6L2	ENST00000312015	human	ensembl	74_37	-1	known	missense	c.829	p.Q277K	0.006	prints_Tropomyosin	prints_Tropomyosin	-	no_errors	GOLGA6L2	HGNC	ENSG00000174450	tier1	-	-	119	1	0.83	59	54	47.37	22	0	0.00	12	5	29.41
C11orf63	0	genome.wustl.edu	37	11	122774688	122774688	+	Missense_Mutation	SNP	A	A	T			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	11	122774688	122774688	A	T	SNP	C11orf63	ENST00000227349	human	ensembl	74_37	+1	known	missense	c.400	p.S134C	0.753	NULL	NULL	-	no_errors	C11orf63	HGNC	ENSG00000109944	tier1	-	-	64	0	0.00	32	19	37.25	76	0	0.00	37	17	31.48
MAPT	0	genome.wustl.edu	37	17	44049253	44049253	+	Missense_Mutation	SNP	C	C	A			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	17	44049253	44049253	C	A	SNP	MAPT	ENST00000344290	human	ensembl	74_37	+1	known	missense	c.162	p.D54E	0.951	NULL	pfam_MAP_tubulin-bd_rpt,prints_Tau	-	no_errors	MAPT	HGNC	ENSG00000186868	tier1	-	-	115	0	0.00	93	26	21.85	105	0	0.00	54	15	21.74
COL12A1	0	genome.wustl.edu	37	6	75893827	75893827	+	Missense_Mutation	SNP	T	T	A			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	6	75893827	75893827	T	A	SNP	COL12A1	ENST00000322507	human	ensembl	74_37	-1	known	missense	c.1031	p.E344V	1.000	pfam_Fibronectin_type3,superfamily_Fibronectin_type3,smart_Fibronectin_type3,pfscan_Fibronectin_type3	pfam_Fibronectin_type3,pfam_VWF_A,pfam_Collagen,superfamily_ConA-like_lec_gl_sf,superfamily_Fibronectin_type3,smart_Fibronectin_type3,smart_VWF_A,smart_Laminin_G,pfscan_Fibronectin_type3,pfscan_VWF_A	-	no_errors	COL12A1	HGNC	ENSG00000111799	tier1	-	-	76	0	0.00	70	22	23.91	119	0	0.00	37	12	24.49
IFNE	0	genome.wustl.edu	37	9	21481377	21481377	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	9	21481377	21481377	G	A	SNP	IFNE	ENST00000448696	human	ensembl	74_37	-1	known	missense	c.317	p.T106M	0.000	pfam_Interferon_alpha/beta/delta,superfamily_4_helix_cytokine-like_core,smart_Interferon_alpha/beta/delta,prints_Interferon_alpha/beta/delta	pfam_Interferon_alpha/beta/delta,superfamily_4_helix_cytokine-like_core,smart_Interferon_alpha/beta/delta,prints_Interferon_alpha/beta/delta	-	no_errors	IFNE	HGNC	ENSG00000184995	tier1	rs147289613	-	60	0	0.00	43	9	17.31	117	0	0.00	77	17	18.09
ZPLD1	0	genome.wustl.edu	37	3	102187922	102187922	+	Silent	SNP	C	C	T			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	3	102187922	102187922	C	T	SNP	ZPLD1	ENST00000306176	human	ensembl	74_37	+1	known	silent	c.924	p.V308	1.000	pfam_ZP_dom,smart_ZP_dom,pfscan_ZP_dom	pfam_ZP_dom,smart_ZP_dom,pfscan_ZP_dom	-	no_errors	ZPLD1	HGNC	ENSG00000170044	tier1	-	-	131	0	0.00	123	26	17.45	63	0	0.00	35	8	18.60
SLC16A2	0	genome.wustl.edu	37	X	73641840	73641840	+	Missense_Mutation	SNP	T	T	A			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	X	73641840	73641840	T	A	SNP	SLC16A2	ENST00000276033	human	ensembl	74_37	+1	known	missense	c.590	p.I197N	1.000	superfamily_MFS_dom_general_subst_transpt	pfam_MFS,superfamily_MFS_dom_general_subst_transpt,pfscan_MFS_dom	-	no_errors	SLC16A2	HGNC	ENSG00000147100	tier1	-	-	207	0	0.00	344	84	19.63	51	0	0.00	72	19	20.88
UPF2	0	genome.wustl.edu	37	10	11984753	11984753	+	Missense_Mutation	SNP	T	T	C			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	10	11984753	11984753	T	C	SNP	UPF2	ENST00000356352	human	ensembl	74_37	-1	known	missense	c.3289	p.I1097V	1.000	pfam_Up-fram_suppressor-2	pfam_MIF4G-like_typ-3,pfam_Up-fram_suppressor-2,superfamily_ARM-type_fold,smart_MIF4G-like_typ-3	-	no_errors	UPF2	HGNC	ENSG00000151461	tier1	-	-	102	0	0.00	67	32	32.32	72	0	0.00	37	17	31.48
CDH19	0	genome.wustl.edu	37	18	64172372	64172372	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	18	64172372	64172372	G	A	SNP	CDH19	ENST00000262150	human	ensembl	74_37	-1	known	missense	c.1996	p.R666W	0.048	pfam_Cadherin_cytoplasmic-dom	pfam_Cadherin,pfam_Cadherin_cytoplasmic-dom,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin,prints_Cadherin	-	no_errors	CDH19	HGNC	ENSG00000071991	tier1	-	-	53	0	0.00	48	22	31.43	95	0	0.00	38	36	48.65
FAM13A	0	genome.wustl.edu	37	4	89660243	89660243	+	Silent	SNP	G	G	A			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	4	89660243	89660243	G	A	SNP	FAM13A	ENST00000264344	human	ensembl	74_37	-1	known	silent	c.2500	p.L834	0.092	NULL	pfam_RhoGAP_dom,superfamily_Rho_GTPase_activation_prot,smart_RhoGAP_dom,pfscan_RhoGAP_dom	-	no_errors	FAM13A	HGNC	ENSG00000138640	tier1	-	-	108	0	0.00	58	41	41.41	115	0	0.00	65	30	31.58
HSPBAP1	0	genome.wustl.edu	37	3	122459105	122459105	+	R	SNP	C	C	T			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	3	122459105	122459105	C	T	SNP	HSPBAP1	ENST00000471534	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	HSPBAP1	HGNC	ENSG00000169087	tier1	-	-	43	0	0.00	15	6	28.57	82	0	0.00	43	8	15.69
BAI1	0	genome.wustl.edu	37	8	143566042	143566042	+	Missense_Mutation	SNP	T	T	A			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	8	143566042	143566042	T	A	SNP	BAI1	ENST00000323289	human	ensembl	74_37	+1	known	missense	c.2225	p.F742Y	1.000	pfam_DUF3497	pfam_GPCR_2_secretin-like,pfam_Thrombospondin_1_rpt,pfam_DUF3497,pfam_GPS_dom,superfamily_Thrombospondin_1_rpt,smart_Thrombospondin_1_rpt,smart_GPCR_2_extracellular_dom,smart_GPS_dom,prints_GPCR_2_brain-spec_angio_inhib,prints_GPCR_2_secretin-like,pfscan_GPS_dom,pfscan_Thrombospondin_1_rpt,pfscan_GPCR_2_extracellular_dom,pfscan_GPCR_2-like	-	no_errors	BAI1	HGNC	ENSG00000181790	tier1	-	-	171	0	0.00	168	30	15.15	47	0	0.00	39	10	20.00
NLRP4	0	genome.wustl.edu	37	19	56370522	56370522	+	Missense_Mutation	SNP	T	T	C			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	19	56370522	56370522	T	C	SNP	NLRP4	ENST00000301295	human	ensembl	74_37	+1	known	missense	c.1763	p.V588A	0.001	NULL	pfam_DAPIN,superfamily_DEATH-like_dom,superfamily_P-loop_NTPase,smart_Leu-rich_rpt_RNase_inh_sub-typ,pfscan_CHT_NTPase,pfscan_DAPIN	-	no_errors	NLRP4	HGNC	ENSG00000160505	tier1	-	-	101	0	0.00	152	21	12.14	190	0	0.00	160	26	13.98
GRIA1	0	genome.wustl.edu	37	5	153078482	153078482	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	5	153078482	153078482	G	A	SNP	GRIA1	ENST00000448073	human	ensembl	74_37	+1	known	missense	c.1331	p.R444H	1.000	pfam_Glu_rcpt_Glu/Gly-bd,pfam_SBP_bac_3,smart_Iontro_glu_rcpt,smart_Glu_rcpt_Glu/Gly-bd	pfam_ANF_lig-bd_rcpt,pfam_Iontro_glu_rcpt,pfam_Glu_rcpt_Glu/Gly-bd,pfam_SBP_bac_3,superfamily_Peripla_BP_I,smart_Iontro_glu_rcpt,smart_Glu_rcpt_Glu/Gly-bd,prints_NMDA_rcpt	-	no_errors	GRIA1	HGNC	ENSG00000155511	tier1	-	-	124	0	0.00	166	30	15.31	99	0	0.00	80	10	10.99
CHMP2B	0	genome.wustl.edu	37	3	87294950	87294950	+	Silent	SNP	G	G	A			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	3	87294950	87294950	G	A	SNP	CHMP2B	ENST00000263780	human	ensembl	74_37	+1	known	silent	c.213	p.Q71	1.000	pfam_Snf7	pfam_Snf7	-	no_errors	CHMP2B	HGNC	ENSG00000083937	tier1	-	-	198	0	0.00	302	72	19.25	97	0	0.00	95	26	21.49
C1orf173	0	genome.wustl.edu	37	1	75037896	75037896	+	Silent	SNP	C	C	T			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	1	75037896	75037896	C	T	SNP	C1orf173	ENST00000326665	human	ensembl	74_37	-1	known	silent	c.3498	p.S1166	0.003	NULL	NULL	-	no_errors	C1orf173	HGNC	ENSG00000178965	tier1	rs200380141	-	41	0	0.00	33	5	13.16	93	0	0.00	53	10	15.87
UTRN	0	genome.wustl.edu	37	6	145157027	145157027	+	Silent	SNP	A	A	G			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	6	145157027	145157027	A	G	SNP	UTRN	ENST00000367545	human	ensembl	74_37	+1	known	silent	c.9777	p.E3259	0.992	pirsf_Dystrophin/utrophin	pfam_Spectrin_repeat,pfam_EF-hand_dom_typ1,pfam_EF-hand_dom_typ2,pfam_CH-domain,pfam_Znf_ZZ,pfam_WW_dom,superfamily_CH-domain,superfamily_WW_dom,smart_CH-domain,smart_Spectrin/alpha-actinin,smart_WW_dom,smart_Znf_ZZ,pirsf_Dystrophin/utrophin,pfscan_CH-domain,pfscan_WW_dom,pfscan_Znf_ZZ	-	no_errors	UTRN	HGNC	ENSG00000152818	tier1	-	-	94	0	0.00	91	21	18.75	71	0	0.00	44	8	15.38
NCSTN	0	genome.wustl.edu	37	1	160325530	160325530	+	Missense_Mutation	SNP	G	G	T			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	1	160325530	160325530	G	T	SNP	NCSTN	ENST00000294785	human	ensembl	74_37	+1	known	missense	c.1438	p.V480L	1.000	pfam_Nicastrin	pfam_Nicastrin	-	no_errors	NCSTN	HGNC	ENSG00000162736	tier1	-	-	64	0	0.00	59	9	13.24	64	0	0.00	51	11	17.74
SCN9A	0	genome.wustl.edu	37	2	167133735	167133735	+	Missense_Mutation	SNP	A	A	G			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	2	167133735	167133735	A	G	SNP	SCN9A	ENST00000303354	human	ensembl	74_37	-1	known	missense	c.2635	p.F879L	1.000	pfam_Ion_trans_dom	pfam_Ion_trans_dom,pfam_DUF3451,pfam_Na_trans_assoc,pfam_PKD1_2_channel,smart_IQ_motif_EF-hand-BS,prints_Na_channel_asu,prints_PKD_2	-	no_errors	SCN9A	HGNC	ENSG00000169432	tier1	-	-	184	0	0.00	127	38	23.03	99	0	0.00	34	12	26.09
OR13C3	0	genome.wustl.edu	37	9	107298240	107298240	+	Silent	SNP	G	G	T			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	9	107298240	107298240	G	T	SNP	OR13C3	ENST00000374781	human	ensembl	74_37	-1	known	silent	c.855	p.I285	0.929	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR13C3	HGNC	ENSG00000204246	tier1	-	-	88	0	0.00	83	15	15.31	57	0	0.00	26	6	18.75
EFR3A	0	genome.wustl.edu	37	8	132957010	132957010	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	8	132957010	132957010	G	A	SNP	EFR3A	ENST00000254624	human	ensembl	74_37	+1	known	missense	c.106	p.D36N	0.986	NULL	superfamily_ARM-type_fold	-	no_errors	EFR3A	HGNC	ENSG00000132294	tier1	-	-	247	0	0.00	239	65	21.31	86	0	0.00	81	15	15.62
SALL3	0	genome.wustl.edu	37	18	76753935	76753935	+	Silent	SNP	G	G	A			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	18	76753935	76753935	G	A	SNP	SALL3	ENST00000537592	human	ensembl	74_37	+1	known	silent	c.1944	p.P648	0.280	NULL	pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2	-	no_errors	SALL3	HGNC	ENSG00000256463	tier1	-	-	38	0	0.00	17	5	22.73	31	0	0.00	37	9	19.57
GZMK	0	genome.wustl.edu	37	5	54329635	54329635	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	5	54329635	54329635	G	A	SNP	GZMK	ENST00000231009	human	ensembl	74_37	+1	known	missense	c.676	p.A226T	0.988	pfam_Peptidase_S1,superfamily_Trypsin-like_Pept_dom,smart_Peptidase_S1,pfscan_Peptidase_S1	pfam_Peptidase_S1,pfam_Peptidase_S1A_nudel,superfamily_Trypsin-like_Pept_dom,smart_Peptidase_S1,pfscan_Peptidase_S1,prints_Peptidase_S1A	-	no_errors	GZMK	HGNC	ENSG00000113088	tier1	rs200562138	-	157	0	0.00	177	78	30.47	88	1	1.12	74	38	33.93
A1CF	0	genome.wustl.edu	37	10	52573658	52573658	+	Missense_Mutation	SNP	G	G	T			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	10	52573658	52573658	G	T	SNP	A1CF	ENST00000282641	human	ensembl	74_37	-1	known	missense	c.1306	p.P436T	1.000	tigrfam_HnRNP_R/Q_splicing_fac	pfam_RRM_dom,smart_RRM_dom,pfscan_RRM_dom,tigrfam_HnRNP_R/Q_splicing_fac	-	no_errors	A1CF	HGNC	ENSG00000148584	tier1	-	-	211	0	0.00	137	48	25.95	105	0	0.00	51	9	15.00
MUC16	0	genome.wustl.edu	37	19	9066657	9066657	+	Missense_Mutation	SNP	G	G	T			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	19	9066657	9066657	G	T	SNP	MUC16	ENST00000397910	human	ensembl	74_37	-1	known	missense	c.20789	p.T6930K	0.000	NULL	pfam_SEA_dom,smart_SEA_dom,pfscan_SEA_dom	-	no_errors	MUC16	HGNC	ENSG00000181143	tier1	-	-	101	0	0.00	144	22	13.25	155	0	0.00	120	18	13.04
KLHL4	0	genome.wustl.edu	37	X	86890736	86890736	+	Missense_Mutation	SNP	C	C	A			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	X	86890736	86890736	C	A	SNP	KLHL4	ENST00000373114	human	ensembl	74_37	+1	known	missense	c.1886	p.A629D	1.000	pfam_Kelch_1,smart_Kelch_1	pfam_Kelch_1,pfam_BACK,pfam_BTB_POZ,pfam_Kelch_2,superfamily_BTB/POZ_fold,smart_BTB/POZ-like,smart_BACK,smart_Kelch_1,pfscan_BTB/POZ-like	-	no_errors	KLHL4	HGNC	ENSG00000102271	tier1	-	-	68	0	0.00	23	101	81.45	41	0	0.00	12	26	68.42
GIMAP8	0	genome.wustl.edu	37	7	150174480	150174480	+	Missense_Mutation	SNP	T	T	A			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	7	150174480	150174480	T	A	SNP	GIMAP8	ENST00000307271	human	ensembl	74_37	+1	known	missense	c.1610	p.F537Y	0.770	pfam_AIG1,superfamily_P-loop_NTPase	pfam_AIG1,superfamily_P-loop_NTPase	-	no_errors	GIMAP8	HGNC	ENSG00000171115	tier1	-	-	93	0	0.00	170	23	11.92	167	0	0.00	150	35	18.82
CLASP2	0	genome.wustl.edu	37	3	33686773	33686773	+	Splice_Site	SNP	C	C	G			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	3	33686773	33686773	C	G	SNP	CLASP2	ENST00000313350	human	ensembl	74_37	-1	known	splice_site	c.34+1	e1+1	1.000	-	-	-	no_errors	CLASP2	HGNC	ENSG00000163539	tier1	-	-	117	0	0.00	67	15	18.29	59	0	0.00	32	4	11.11
KYNU	0	genome.wustl.edu	37	2	143790838	143790838	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	2	143790838	143790838	G	A	SNP	KYNU	ENST00000264170	human	ensembl	74_37	+1	known	missense	c.989	p.R330Q	1.000	pfam_Aminotrans_V/Cys_dSase,superfamily_PyrdxlP-dep_Trfase,tigrfam_Kynureninase	pfam_Aminotrans_V/Cys_dSase,superfamily_PyrdxlP-dep_Trfase,tigrfam_Kynureninase	-	no_errors	KYNU	HGNC	ENSG00000115919	tier1	rs142934146	-	208	0	0.00	80	76	48.72	111	0	0.00	34	25	41.67
CSE1L	0	genome.wustl.edu	37	20	47707377	47707377	+	Splice_Site	SNP	G	G	A			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	20	47707377	47707377	G	A	SNP	CSE1L	ENST00000262982	human	ensembl	74_37	+1	known	splice_site	c.2279+1	e19+1	1.000	-	-	-	no_errors	CSE1L	HGNC	ENSG00000124207	tier1	-	-	102	0	0.00	87	20	18.69	84	0	0.00	62	16	20.51
CTBP2	0	genome.wustl.edu	37	10	126686543	126686543	+	Silent	SNP	G	G	A			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	10	126686543	126686543	G	A	SNP	CTBP2	ENST00000309035	human	ensembl	74_37	-1	known	silent	c.2175	p.L725	1.000	pfam_D-isomer_2_OHA_DH_D-bd,pfam_D-isomer_2_OHA_DH_cat_dom	pfam_D-isomer_2_OHA_DH_D-bd,pfam_D-isomer_2_OHA_DH_cat_dom	-	no_errors	CTBP2	HGNC	ENSG00000175029	tier1	-	-	118	0	0.00	53	20	27.40	12	0	0.00	11	4	26.67
ZNF25	0	genome.wustl.edu	37	10	38241130	38241130	+	Silent	SNP	C	C	T			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	10	38241130	38241130	C	T	SNP	ZNF25	ENST00000302609	human	ensembl	74_37	-1	known	silent	c.1296	p.G432	0.768	pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF25	HGNC	ENSG00000175395	tier1	-	-	38	0	0.00	14	9	39.13	60	0	0.00	57	11	16.18
NIT1	0	genome.wustl.edu	37	1	161089713	161089713	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	1	161089713	161089713	G	A	SNP	NIT1	ENST00000368009	human	ensembl	74_37	+1	known	missense	c.562	p.E188K	0.253	pfam_C-N_Hydrolase,superfamily_C-N_Hydrolase,pfscan_C-N_Hydrolase	pfam_C-N_Hydrolase,superfamily_C-N_Hydrolase,pfscan_C-N_Hydrolase	-	no_errors	NIT1	HGNC	ENSG00000158793	tier1	-	-	130	0	0.00	124	12	8.82	87	0	0.00	54	10	15.62
POGZ	0	genome.wustl.edu	37	1	151384868	151384868	+	Missense_Mutation	SNP	C	C	A			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	1	151384868	151384868	C	A	SNP	POGZ	ENST00000271715	human	ensembl	74_37	-1	known	missense	c.1683	p.K561N	1.000	smart_Znf_C2H2-like	pfam_DDE_SF_endonuclease_CENPB-like,pfam_HTH_CenpB_D-bd_dom,superfamily_Homeodomain-like,smart_Znf_C2H2-like,smart_HTH_CenpB_D-bd_dom,pfscan_Znf_C2H2	-	no_errors	POGZ	HGNC	ENSG00000143442	tier1	-	-	119	0	0.00	32	34	51.52	140	0	0.00	27	28	50.91
EFR3A	0	genome.wustl.edu	37	8	132957051	132957051	+	Silent	SNP	G	G	A			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	8	132957051	132957051	G	A	SNP	EFR3A	ENST00000254624	human	ensembl	74_37	+1	known	silent	c.147	p.E49	1.000	NULL	superfamily_ARM-type_fold	-	no_errors	EFR3A	HGNC	ENSG00000132294	tier1	-	-	216	0	0.00	221	59	21.07	106	0	0.00	99	23	18.85
METTL25	0	genome.wustl.edu	37	12	82752386	82752386	+	Silent	SNP	C	C	G			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	12	82752386	82752386	C	G	SNP	METTL25	ENST00000248306	human	ensembl	74_37	+1	known	silent	c.42	p.P14	0.058	NULL	NULL	-	no_errors	METTL25	HGNC	ENSG00000127720	tier1	-	-	68	0	0.00	68	12	15.00	22	0	0.00	29	7	19.44
ARHGAP30	0	genome.wustl.edu	37	1	161018648	161018648	+	Silent	SNP	T	T	C			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	1	161018648	161018648	T	C	SNP	ARHGAP30	ENST00000368013	human	ensembl	74_37	-1	known	silent	c.2163	p.K721	0.010	NULL	pfam_RhoGAP_dom,superfamily_Rho_GTPase_activation_prot,smart_RhoGAP_dom,pfscan_RhoGAP_dom	-	no_errors	ARHGAP30	HGNC	ENSG00000186517	tier1	-	-	115	0	0.00	79	39	33.05	78	0	0.00	40	37	48.05
PIM2	0	genome.wustl.edu	37	X	48771549	48771549	+	Silent	SNP	C	C	A			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	X	48771549	48771549	C	A	SNP	PIM2	ENST00000376509	human	ensembl	74_37	-1	known	silent	c.795	p.R265	1.000	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_LipoPS_kinase,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	-	no_errors	PIM2	HGNC	ENSG00000102096	tier1	-	-	103	0	0.00	146	52	26.26	43	0	0.00	62	18	22.50
RASGRF1	0	genome.wustl.edu	37	15	79310205	79310205	+	Silent	SNP	G	G	A			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	15	79310205	79310205	G	A	SNP	RASGRF1	ENST00000419573	human	ensembl	74_37	-1	known	silent	c.1650	p.I550	0.430	smart_Pleckstrin_homology,pfscan_Pleckstrin_homology	pfam_RasGRF_CDC25,pfam_Ras-like_Gua-exchang_fac_N,pfam_DH-domain,pfam_Pleckstrin_homology,superfamily_Ras_GEF_dom,superfamily_DH-domain,smart_Pleckstrin_homology,smart_DH-domain,smart_Ras-like_Gua-exchang_fac_N,smart_RasGRF_CDC25,pfscan_IQ_motif_EF-hand-BS,pfscan_Pleckstrin_homology,pfscan_DH-domain,pfscan_RasGRF_CDC25,pfscan_Ras-like_Gua-exchang_fac_N	-	no_errors	RASGRF1	HGNC	ENSG00000058335	tier1	-	-	194	0	0.00	186	35	15.84	130	0	0.00	85	14	14.14
PEG3	0	genome.wustl.edu	37	19	57326959	57326959	+	Missense_Mutation	SNP	C	C	A			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	19	57326959	57326959	C	A	SNP	PEG3	ENST00000326441	human	ensembl	74_37	-1	known	missense	c.2851	p.V951L	0.566	NULL	pfam_Znf_C2H2,pfam_Tscrpt_reg_SCAN,superfamily_Retrov_capsid_C,smart_Tscrpt_reg_SCAN,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Tscrpt_reg_SCAN	-	no_errors	PEG3	HGNC	ENSG00000198300	tier1	-	-	97	0	0.00	99	61	38.12	107	0	0.00	79	32	28.83
TP53	0	genome.wustl.edu	37	17	7578176	7578176	+	Splice_Site	SNP	C	C	A			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	17	7578176	7578176	C	A	SNP	TP53	ENST00000269305	human	ensembl	74_37	-1	known	splice_site	c.672+1	e5+1	1.000	-	-	-	no_errors	TP53	HGNC	ENSG00000141510	tier1	-	-	148	0	0.00	41	168	80.38	114	0	0.00	18	100	84.75
ROCK1P1	0	genome.wustl.edu	37	18	117148	117148	+	R	SNP	C	C	A			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	18	117148	117148	C	A	SNP	ROCK1P1	ENST00000576266	human	ensembl	74_37	+1	known	rna	NULL	NULL	1.000	-	-	-	no_errors	ROCK1P1	HGNC	ENSG00000263006	tier1	-	-	203	0	0.00	183	34	15.67	141	0	0.00	119	23	16.08
PPP1R2P1	0	genome.wustl.edu	37	6	32847349	32847349	+	R	SNP	C	C	G			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	6	32847349	32847349	C	G	SNP	PPP1R2P1	ENST00000420261	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.002	-	-	-	no_errors	PPP1R2P1	HGNC	ENSG00000234515	tier1	-	-	144	0	0.00	94	16	14.55	14	0	0.00	10	4	28.57
TBC1D32	0	genome.wustl.edu	37	6	121544380	121544385	+	Splice_Site	DEL	ACAATA	ACAATA	-			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	ACAATA	ACAATA	ACAATA	-	ACAATA	ACAATA	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	6	121544380	121544385	ACAATA	-	DEL	TBC1D32	ENST00000464622	human	ensembl	74_37	-1	known	splice_site_del	c.327+5_0	e4-1	1.000:0.999:0.878:0.870:0.829:0.780	-	-	-	no_errors	TBC1D32	HGNC	ENSG00000146350	tier1			86	0	0.00	40	14	25.93	86	0	0.00	40	14	25.93
ENSG00000269939	0	genome.wustl.edu	37	11	82896849	82896852	+	R	DEL	TTCT	TTCT	-			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	TTCT	TTCT	TTCT	-	TTCT	TTCT	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	11	82896849	82896852	TTCT	-	DEL	ENSG00000269939	ENST00000602322	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.986:0.999:1.000:1.000	-	-	-	no_errors	RP11-727A23.11	Clone_based_vega_gene	ENSG00000269939	tier1			114	0	0.00	50	57	53.27	80	0	0.00	20	27	57.45
MASP1	0	genome.wustl.edu	37	3	186974575	186974575	+	Frame_Shift_Del	DEL	G	G	-			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	G	G	G	-	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	3	186974575	186974575	G	-	DEL	MASP1	ENST00000296280	human	ensembl	74_37	-1	known	frame_shift_del	c.621	p.K208fs	1.000	pfam_CUB_dom,superfamily_CUB_dom,smart_CUB_dom,pfscan_CUB_dom	pfam_Peptidase_S1,pfam_CUB_dom,pfam_Sushi_SCR_CCP,pfam_EGF-like_Ca-bd_dom,superfamily_Trypsin-like_Pept_dom,superfamily_CUB_dom,superfamily_Sushi_SCR_CCP,smart_CUB_dom,smart_EGF-like_Ca-bd_dom,smart_Sushi_SCR_CCP,smart_Peptidase_S1,prints_Peptidase_S1A,pfscan_CUB_dom,pfscan_Sushi_SCR_CCP,pfscan_Peptidase_S1	-	no_errors	MASP1	HGNC	ENSG00000127241	tier1			67	0	0.00	77	12	13.48	125	0	0.00	88	26	22.81
PEPLD	0	genome.wustl.edu	37	7	102760459	102760459	+	Frame_Shift_Del	DEL	G	G	-			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	G	G	G	-	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	7	102760459	102760459	G	-	DEL	PEPLD	ENST00000455523	human	ensembl	74_37	-1	known	frame_shift_del	c.725	p.P242fs	1.000	NULL	NULL	-	no_errors	PEPLD	HGNC	ENSG00000161048	tier1			86	0	0.00	113	17	13.08	124	0	0.00	132	20	13.16
KIFC3	0	genome.wustl.edu	37	16	57832148	57832148	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	16	57832148	57832148	G	A	SNP	KIFC3	ENST00000379655	human	ensembl	74_37	-1	known	missense	c.8	p.P3L	0.995	NULL	pfam_Kinesin_motor_dom,superfamily_P-loop_NTPase,smart_Kinesin_motor_dom,pfscan_Kinesin_motor_dom,prints_Kinesin_motor_dom	-	no_errors	KIFC3	HGNC	ENSG00000140859	tier1	-	-	14	0	0.00	18	8	30.77	8	0	0.00	2	3	60.00
PCDHA8	0	genome.wustl.edu	37	5	140223088	140223088	+	Missense_Mutation	SNP	A	A	C			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	A	A	A	C	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	5	140223088	140223088	A	C	SNP	PCDHA8	ENST00000531613	human	ensembl	74_37	+1	known	missense	c.2182	p.T728P	0.000	NULL	pfam_Cadherin,pfam_Cadherin_N,superfamily_Cadherin-like,smart_Cadherin,prints_Cadherin,pfscan_Cadherin	-	no_errors	PCDHA8	HGNC	ENSG00000204962	tier1	-	-	94	0	0.00	99	22	18.18	21	0	0.00	9	2	18.18
ZFHX3	0	genome.wustl.edu	37	16	72827758	72827758	+	Silent	SNP	T	T	A			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	16	72827758	72827758	T	A	SNP	ZFHX3	ENST00000268489	human	ensembl	74_37	-1	known	silent	c.8823	p.G2941	1.000	superfamily_Homeodomain-like	pfam_Homeobox_dom,superfamily_Homeodomain-like,superfamily_Adenylate_cyclase-assoc_CAP_N,smart_Znf_C2H2-like,smart_Znf_U1,smart_Homeobox_dom,pfscan_Homeobox_dom,pfscan_Znf_C2H2	-	no_errors	ZFHX3	HGNC	ENSG00000140836	tier1	-	-	35	0	0.00	14	25	21.19	32	0	0.00	9	17	22.37
ZNF716	0	genome.wustl.edu	37	7	57529220	57529220	+	Silent	SNP	C	C	G			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	7	57529220	57529220	C	G	SNP	ZNF716	ENST00000420713	human	ensembl	74_37	+1	known	silent	c.1053	p.L351	0.772	pfscan_Znf_C2H2	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF716	HGNC	ENSG00000182111	tier1	-	-	94	0	0.00	102	54	34.62	16	0	0.00	8	4	33.33
TXNRD1	0	genome.wustl.edu	37	12	104725408	104725408	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	12	104725408	104725408	G	A	SNP	TXNRD1	ENST00000429002	human	ensembl	74_37	+1	known	missense	c.1639	p.E547K	1.000	pfam_Pyr_nucl-diS_OxRdtase_dimer,superfamily_FAD/D-linked_Rdtase_dimer,tigrfam_Thioredoxin/glutathione_Rdtase	pfam_Pyr_nucl-diS_OxRdtase_FAD/D,pfam_Pyr_nucl-diS_OxRdtase_dimer,pfam_Pyr_OxRdtase_D-bd_dom,pfam_FAD_bind_dom,pfam_Glutaredoxin,superfamily_FAD/D-linked_Rdtase_dimer,superfamily_Thioredoxin-like_fold,prints_FAD_pyr_nucl-diS_OxRdtase,prints_Hg_reductase,prints_Pyridine_nuc-diS_OxRdtase_2,tigrfam_Thioredoxin/glutathione_Rdtase	-	no_errors	TXNRD1	HGNC	ENSG00000198431	tier1	-	-	257	0	0.00	336	31	8.45	116	0	0.00	102	4	3.77
FDXR	0	genome.wustl.edu	37	17	72860089	72860089	+	Missense_Mutation	SNP	T	T	C			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	17	72860089	72860089	T	C	SNP	FDXR	ENST00000581530	human	ensembl	74_37	-1	known	missense	c.1121	p.D374G	0.996	NULL	pfam_Pyr_nucl-diS_OxRdtase_FAD/D	-	no_errors	FDXR	HGNC	ENSG00000161513	tier1	-	-	79	0	0.00	83	17	16.83	84	0	0.00	93	8	7.92
FDXR	0	genome.wustl.edu	37	17	72860090	72860090	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	17	72860090	72860090	C	T	SNP	FDXR	ENST00000581530	human	ensembl	74_37	-1	known	missense	c.1120	p.D374N	0.976	NULL	pfam_Pyr_nucl-diS_OxRdtase_FAD/D	-	no_errors	FDXR	HGNC	ENSG00000161513	tier1	-	-	77	0	0.00	82	16	16.33	84	0	0.00	93	9	8.82
MX1	0	genome.wustl.edu	37	21	42808961	42808961	+	Silent	SNP	G	G	T			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	21	42808961	42808961	G	T	SNP	MX1	ENST00000398598	human	ensembl	74_37	+1	known	silent	c.318	p.P106	0.911	pfam_Dynamin_GTPase,superfamily_P-loop_NTPase,smart_Dynamin_GTPase,prints_Dynamin_SF	pfam_Dynamin_central,pfam_Dynamin_GTPase,pfam_GED,superfamily_P-loop_NTPase,smart_Dynamin_GTPase,smart_GED,prints_Dynamin_SF	-	no_errors	MX1	HGNC	ENSG00000157601	tier1	-	-	157	0	0.00	108	14	11.48	120	1	0.83	112	12	9.68
AKAP6	0	genome.wustl.edu	37	14	33291068	33291068	+	Missense_Mutation	SNP	C	C	A			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	14	33291068	33291068	C	A	SNP	AKAP6	ENST00000280979	human	ensembl	74_37	+1	known	missense	c.4049	p.A1350E	0.000	NULL	smart_Spectrin/alpha-actinin	-	no_errors	AKAP6	HGNC	ENSG00000151320	tier1	-	-	51	0	0.00	92	14	13.21	62	0	0.00	152	10	6.17
VWF	0	genome.wustl.edu	37	12	6131103	6131103	+	Missense_Mutation	SNP	T	T	C			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	12	6131103	6131103	T	C	SNP	VWF	ENST00000261405	human	ensembl	74_37	-1	known	missense	c.3637	p.T1213A	1.000	pirsf_VWF	pirsf_VWF,pfam_VWF_type-D,pfam_VWF_A,pfam_Unchr_dom_Cys-rich,pfam_TIL_dom,pfam_VWF_C,superfamily_TIL_dom,smart_VWF_type-D,smart_Unchr_dom_Cys-rich,smart_VWC_out,smart_VWF_C,smart_VWF_A,smart_Cys_knot_C,pfscan_Cys_knot_C,pfscan_VWF_A,pfscan_VWF_C	-	no_errors	VWF	HGNC	ENSG00000110799	tier1	-	-	330	0	0.00	405	71	14.79	86	0	0.00	83	8	8.70
DOCK5	0	genome.wustl.edu	37	8	25209283	25209283	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	8	25209283	25209283	C	T	SNP	DOCK5	ENST00000276440	human	ensembl	74_37	+1	known	missense	c.2791	p.R931W	1.000	superfamily_ARM-type_fold	pfam_DOCK_C,pfam_SH3_domain,pfam_SH3_2,superfamily_SH3_domain,superfamily_ARM-type_fold,smart_SH3_domain,pfscan_SH3_domain	-	no_errors	DOCK5	HGNC	ENSG00000147459	tier1	-	-	116	0	0.00	90	11	10.78	113	0	0.00	88	6	6.38
RNLS	0	genome.wustl.edu	37	10	90034752	90034752	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	10	90034752	90034752	C	T	SNP	RNLS	ENST00000371947	human	ensembl	74_37	-1	known	missense	c.914	p.S305N	0.001	NULL	pfam_Amino_oxidase	-	no_errors	RNLS	HGNC	ENSG00000184719	tier1	-	-	81	0	0.00	55	8	12.50	77	0	0.00	81	7	7.95
SEL1L2	0	genome.wustl.edu	37	20	13830169	13830169	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	20	13830169	13830169	G	A	SNP	SEL1L2	ENST00000284951	human	ensembl	74_37	-1	known	missense	c.2029	p.P677S	0.450	NULL	pfam_Sel1-like,smart_Sel1-like	-	no_errors	SEL1L2	HGNC	ENSG00000101251	tier1	-	-	180	1	0.55	223	32	12.50	167	0	0.00	221	24	9.68
PAPPA2	0	genome.wustl.edu	37	1	176679192	176679192	+	Silent	SNP	A	A	G			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	1	176679192	176679192	A	G	SNP	PAPPA2	ENST00000367662	human	ensembl	74_37	+1	known	silent	c.3531	p.V1177	0.002	NULL	pfam_Notch_dom,pfam_Sushi_SCR_CCP,pfam_Peptidase_M43,superfamily_ConA-like_lec_gl_sf,superfamily_Sushi_SCR_CCP,superfamily_Fibronectin_type3,superfamily_Notch_dom,smart_LamG-like,smart_Notch_dom,smart_Sushi_SCR_CCP,pfscan_Sushi_SCR_CCP,tigrfam_Myxo_disulph_rpt	-	no_errors	PAPPA2	HGNC	ENSG00000116183	tier1	-	-	100	0	0.00	141	19	11.88	118	0	0.00	112	12	9.68
CDH10	0	genome.wustl.edu	37	5	24509886	24509886	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	5	24509886	24509886	C	T	SNP	CDH10	ENST00000264463	human	ensembl	74_37	-1	known	missense	c.1045	p.E349K	0.996	pfam_Cadherin,superfamily_Cadherin-like,smart_Cadherin,prints_Cadherin,pfscan_Cadherin	pfam_Cadherin,pfam_Cadherin_cytoplasmic-dom,superfamily_Cadherin-like,smart_Cadherin,prints_Cadherin,pfscan_Cadherin	-	no_errors	CDH10	HGNC	ENSG00000040731	tier1	rs138533676	-	114	0	0.00	170	23	11.92	72	0	0.00	97	8	7.62
ABCA13	0	genome.wustl.edu	37	7	48312581	48312581	+	Silent	SNP	C	C	T			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	7	48312581	48312581	C	T	SNP	ABCA13	ENST00000435803	human	ensembl	74_37	+1	known	silent	c.3318	p.H1106	0.000	NULL	pfam_ABC_transporter-like,superfamily_P-loop_NTPase,smart_AAA+_ATPase,pfscan_ABC_transporter-like	-	no_errors	ABCA13	HGNC	ENSG00000179869	tier1	-	-	101	0	0.00	119	19	13.77	101	0	0.00	73	8	9.88
ZSCAN1	0	genome.wustl.edu	37	19	58549273	58549273	+	Silent	SNP	C	C	T			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	19	58549273	58549273	C	T	SNP	ZSCAN1	ENST00000282326	human	ensembl	74_37	+1	known	silent	c.69	p.D23	0.000	NULL	pfam_Tscrpt_reg_SCAN,superfamily_Retrov_capsid_C,smart_Tscrpt_reg_SCAN,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Tscrpt_reg_SCAN	-	no_errors	ZSCAN1	HGNC	ENSG00000152467	tier1	-	-	60	0	0.00	47	5	9.62	13	0	0.00	8	0	0.00
ENSG00000267219	0	genome.wustl.edu	37	19	34849728	34849729	+	R	INS	-	-	TTGGGAGGCCAAG			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	19	34849728	34849729	-	TTGGGAGGCCAAG	INS	ENSG00000267219	ENST00000591311	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.005:0.003	-	-	-	no_errors	AC010504.2	Clone_based_vega_gene	ENSG00000267219	tier1			0	0	0.00	0	0	0.00	0	0	0.00	0	0	0.00
EOMES	0	genome.wustl.edu	37	3	27763427	27763428	+	In_Frame_Ins	INS	-	-	CGGCGC			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	3	27763427	27763428	-	CGGCGC	INS	EOMES	ENST00000449599	human	ensembl	74_37	-1	known	in_frame_ins	c.359_358	p.120in_frame_insGA	0.116:0.075	NULL	pfam_TF_T-box,superfamily_p53-like_TF_D-bd,smart_TF_T-box,pfscan_TF_T-box,prints_TF_T-box	-	no_errors	EOMES	HGNC	ENSG00000163508	tier1			0	0	0.00	0	0	0.00	0	0	0.00	0	0	0.00
KRTAP9-2	0	genome.wustl.edu	37	17	39383043	39383043	+	Missense_Mutation	SNP	G	G	T			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	17	39383043	39383043	G	T	SNP	KRTAP9-2	ENST00000377721	human	ensembl	74_37	+1	known	missense	c.137	p.S46I	1.000	NULL	NULL	-	no_errors	KRTAP9-2	HGNC	ENSG00000239886	tier1	-	-	231	0	0.00	136	40	22.60	3	0	0.00	3	0	0.00
LOC100507033	0	genome.wustl.edu	37	3	194219220	194219221	+	R	INS	-	-	TTTTG			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	3	194219220	194219221	-	TTTTG	INS	LOC100507033	ENST00000455557	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000:0.000	-	-	-	no_errors	AC108676.1	Clone_based_vega_gene	ENSG00000244675	tier1			0	0	0.00	0	0	0.00	0	0	0.00	0	0	0.00
MT-ATP8	0	genome.wustl.edu	37	MT	8418	8418	+	Missense_Mutation	SNP	T	T	C			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	MT	8418	8418	T	C	SNP	MT-ATP8	ENST00000361851	human	ensembl	74_37	+1	known	missense	c.53	p.L18P	NULL	pfam_ATPase_F0-cplx_su8_mt_metazoan	pfam_ATPase_F0-cplx_su8_mt_metazoan	-	no_errors	MT-ATP8	HGNC	ENSG00000228253	tier1	-	-	25	0	0.00	16	4	20.00	2	0	0.00	2	0	0.00
NCOR2	0	genome.wustl.edu	37	12	124856967	124856967	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	12	124856967	124856967	G	A	SNP	NCOR2	ENST00000356219	human	ensembl	74_37	-1	known	missense	c.2408	p.T803I	0.000	NULL	pfam_SANT/Myb,superfamily_Homeodomain-like,smart_SANT/Myb,pfscan_Myb-like_dom	-	no_errors	NCOR2	HGNC	ENSG00000196498	tier1	-	-	31	0	0.00	18	4	18.18	0	0	0.00	0	0	0.00
RPLP2	0	genome.wustl.edu	37	11	810010	810018	+	R	DEL	CTCCGCCGC	CTCCGCCGC	-			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	CTCCGCCGC	CTCCGCCGC					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	11	810010	810018	CTCCGCCGC	-	DEL	RPLP2	ENST00000532004	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.000:0.000:0.006:0.006:0.009:0.013:0.013:0.025:0.024	-	-	-	no_errors	RPLP2	HGNC	ENSG00000177600	tier1			4	0	0.00	1	0	0.00	4	0	0.00	1	0	0.00
UFL1	0	genome.wustl.edu	37	6	96969559	96969578	+	R	DEL	AACCCCCAGCGCCGCGGTAC	AACCCCCAGCGCCGCGGTAC	-			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	AACCCCCAGCGCCGCGGTAC	AACCCCCAGCGCCGCGGTAC					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	6	96969559	96969578	AACCCCCAGCGCCGCGGTAC	-	DEL	UFL1	ENST00000461673	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.000:0.000:0.000:0.000:0.000:0.001:0.001:0.000:0.001:0.001:0.003:0.006:0.006:0.002:0.000:0.000:0.000:0.000:0.000:0.000	-	-	-	no_errors	UFL1	HGNC	ENSG00000014123	tier1			2	0	0.00	1	0	0.00	2	0	0.00	1	0	0.00
ENSG00000273433	0	genome.wustl.edu	37	7	27192088	27192089	+	R	INS	-	-	GGCCT			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	7	27192088	27192089	-	GGCCT	INS	ENSG00000273433	ENST00000467897	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.007:0.074	-	-	-	no_errors	RP1-170O19.22	Clone_based_vega_gene	ENSG00000273433	tier1			2	0	0.00	4	7	63.64	2	0	0.00	4	7	63.64
SELM	0	genome.wustl.edu	37	22	31503500	31503500	+	R	SNP	G	G	A			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	22	31503500	31503500	G	A	SNP	SELM	ENST00000460642	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.013	-	-	-	no_errors	SELM	Uniprot_gn	ENSG00000198832	tier1	-	-	47	0	0.00	59	9	13.24	2	0	0.00	5	2	28.57
DPY19L3	0	genome.wustl.edu	37	19	32927362	32927362	+	Silent	SNP	C	C	T			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	19	32927362	32927362	C	T	SNP	DPY19L3	ENST00000342179	human	ensembl	74_37	+1	known	silent	c.339	p.G113	1.000	pfam_Dpy-19	pfam_Dpy-19	-	no_errors	DPY19L3	HGNC	ENSG00000178904	tier1	-	-	236	0	0.00	310	65	17.33	105	0	0.00	67	2	2.90
TMTC2	0	genome.wustl.edu	37	12	83455574	83455574	+	Silent	SNP	G	G	A			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	12	83455574	83455574	G	A	SNP	TMTC2	ENST00000321196	human	ensembl	74_37	+1	known	silent	c.2295	p.E765	1.000	smart_TPR_repeat,pfscan_TPR-contain_dom	pfam_TPR_1,pfam_TPR_2,pfam_DUF1736,pfam_TPR-4,smart_TPR_repeat,pfscan_TPR_repeat,pfscan_TPR-contain_dom	-	no_errors	TMTC2	HGNC	ENSG00000179104	tier1	-	-	99	0	0.00	131	21	13.82	46	0	0.00	37	3	7.50
COBLL1	0	genome.wustl.edu	37	2	165551295	165551296	+	Frame_Shift_Ins	INS	-	-	A			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	2	165551295	165551296	-	A	INS	COBLL1	ENST00000194871	human	ensembl	74_37	-1	known	frame_shift_ins	c.2922_2921	p.L974fs	0.958:0.972	NULL	pfam_Cordon-bleu_ubiquitin_domain,pfscan_WH2_dom	-	no_errors	COBLL1	HGNC	ENSG00000082438	tier1			95	0	0.00	48	5	9.43	53	0	0.00	35	2	5.41
ASIC2	0	genome.wustl.edu	37	17	31348283	31348285	+	In_Frame_Del	DEL	ATA	ATA	-			TCGA-DX-AB2V-01A-11D-A417-09	TCGA-DX-AB2V-10A-01D-A41A-09	ATA	ATA					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	6a7b2aef-6971-4bfc-a6d8-0cdce906213e	0cd670fd-cc01-4335-9b59-a21f57dd6b99	17	31348283	31348285	ATA	-	DEL	ASIC2	ENST00000225823	human	ensembl	74_37	-1	known	in_frame_del	c.1395_1393	p.Y465in_frame_del	1.000:1.000:1.000	pfam_Na+channel_ASC,prints_Na+channel_ASC,tigrfam_EnaC	pfam_Na+channel_ASC,prints_Na+channel_ASC,tigrfam_EnaC	-	no_errors	ASIC2	HGNC	ENSG00000108684	tier1			79	0	0.00	67	16	19.28	75	0	0.00	41	2	4.65