Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	default_gene_name	gene_name_source	 ensembl_gene_id	tier	dbSNP	GMAF	n_ref_count	n_alt_count	normal_vaf	t_ref_count	t_alt_count	tumor_vaf	n_ref_count_val	n_alt_count_val	normal_vaf_val	t_ref_count_val	t_alt_count_val	tumor_vaf_val
SKIV2L2	0	genome.wustl.edu	37	5	54624535	54624535	+	Missense_Mutation	SNP	G	G	A			TCGA-HB-A3L4-01A-11D-A21Q-09	TCGA-HB-A3L4-10A-01D-A21Q-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	23976ad7-4b4a-48ec-b407-36fd75119645	6bdcbf01-b44e-4688-8d32-1892a63a3d28	5	54624535	54624535	G	A	SNP	SKIV2L2	ENST00000506750	human	ensembl	74_37	+1	known	missense	c.206	p.R69H	0.902	NULL	NULL	-	no_errors	SKIV2L2	HGNC	ENSG00000039123	tier1	-	-	79	0	0.00	52	48	48.00	74	0	0.00	39	31	44.29
TMEM109	0	genome.wustl.edu	37	11	60690262	60690262	+	R	SNP	A	A	C			TCGA-HB-A3L4-01A-11D-A21Q-09	TCGA-HB-A3L4-10A-01D-A21Q-09	A	A	A	C	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	23976ad7-4b4a-48ec-b407-36fd75119645	6bdcbf01-b44e-4688-8d32-1892a63a3d28	11	60690262	60690262	A	C	SNP	TMEM109	ENST00000540280	human	ensembl	74_37	+1	putative	rna	NULL	NULL	1.000	-	-	-	no_errors	TMEM109	HGNC	ENSG00000110108	tier1	-	-	33	0	0.00	28	22	44.00	48	0	0.00	14	10	41.67
ADGB	0	genome.wustl.edu	37	6	147103231	147103231	+	Missense_Mutation	SNP	C	C	A			TCGA-HB-A3L4-01A-11D-A21Q-09	TCGA-HB-A3L4-10A-01D-A21Q-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	23976ad7-4b4a-48ec-b407-36fd75119645	6bdcbf01-b44e-4688-8d32-1892a63a3d28	6	147103231	147103231	C	A	SNP	ADGB	ENST00000397944	human	ensembl	74_37	+1	known	missense	c.3938	p.S1313Y	1.000	NULL	pfam_Peptidase_C2_calpain_cat,superfamily_Globin-like,smart_Peptidase_C2_calpain_cat,pfscan_IQ_motif_EF-hand-BS,pfscan_Peptidase_C2_calpain_cat	-	no_errors	ADGB	HGNC	ENSG00000118492	tier1	-	-	27	0	0.00	19	17	47.22	88	0	0.00	27	37	57.81
PLEKHM1	0	genome.wustl.edu	37	17	43530773	43530773	+	Silent	SNP	C	C	T			TCGA-HB-A3L4-01A-11D-A21Q-09	TCGA-HB-A3L4-10A-01D-A21Q-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	23976ad7-4b4a-48ec-b407-36fd75119645	6bdcbf01-b44e-4688-8d32-1892a63a3d28	17	43530773	43530773	C	T	SNP	PLEKHM1	ENST00000430334	human	ensembl	74_37	-1	known	silent	c.2445	p.L815	1.000	NULL	pfam_Run,superfamily_Znf_FYVE_PHD,smart_Run,smart_Pleckstrin_homology,smart_Prot_Kinase_C-like_PE/DAG-bd,pfscan_Pleckstrin_homology,pfscan_Run,pfscan_Prot_Kinase_C-like_PE/DAG-bd	-	no_errors	PLEKHM1	HGNC	ENSG00000225190	tier1	-	-	60	0	0.00	42	42	50.00	63	0	0.00	34	29	46.03
PLX2	0	genome.wustl.edu	37	1	208390466	208390466	+	Missense_Mutation	SNP	T	T	A			TCGA-HB-A3L4-01A-11D-A21Q-09	TCGA-HB-A3L4-10A-01D-A21Q-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	23976ad7-4b4a-48ec-b407-36fd75119645	6bdcbf01-b44e-4688-8d32-1892a63a3d28	1	208390466	208390466	T	A	SNP	PLX2	ENST00000367033	human	ensembl	74_37	-1	known	missense	c.802	p.I268F	1.000	pfam_Semap_dom,superfamily_Semap_dom,smart_Semap_dom,pfscan_Semap_dom	pfam_Plexin_cytoplasmic_RasGAP_dom,pfam_Semap_dom,pfam_IPT,pfam_Plexin_repeat,superfamily_Semap_dom,superfamily_Rho_GTPase_activation_prot,superfamily_Ig_E-set,superfamily_Plexin-like_fold,smart_Semap_dom,smart_Plexin-like_fold,smart_IPT,pfscan_Semap_dom	-	no_errors	PLX2	HGNC	ENSG00000076356	tier1	-	-	33	0	0.00	37	12	24.49	95	0	0.00	62	23	26.74
GPR133	0	genome.wustl.edu	37	12	131498757	131498757	+	Missense_Mutation	SNP	A	A	G			TCGA-HB-A3L4-01A-11D-A21Q-09	TCGA-HB-A3L4-10A-01D-A21Q-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	23976ad7-4b4a-48ec-b407-36fd75119645	6bdcbf01-b44e-4688-8d32-1892a63a3d28	12	131498757	131498757	A	G	SNP	GPR133	ENST00000261654	human	ensembl	74_37	+1	known	missense	c.1345	p.M449V	0.007	NULL	pfam_GPCR_2_secretin-like,pfam_GPS_dom,superfamily_ConA-like_lec_gl_sf,smart_GPS_dom,pfscan_GPS_dom,pfscan_GPCR_2-like,prints_GPCR_2_secretin-like	-	no_errors	GPR133	HGNC	ENSG00000111452	tier1	-	-	41	0	0.00	44	17	27.87	43	0	0.00	18	17	48.57
REEP5	0	genome.wustl.edu	37	5	112222764	112222764	+	Silent	SNP	G	G	T			TCGA-HB-A3L4-01A-11D-A21Q-09	TCGA-HB-A3L4-10A-01D-A21Q-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	23976ad7-4b4a-48ec-b407-36fd75119645	6bdcbf01-b44e-4688-8d32-1892a63a3d28	5	112222764	112222764	G	T	SNP	REEP5	ENST00000379638	human	ensembl	74_37	-1	known	silent	c.468	p.V156	1.000	NULL	pfam_TB2_DP1_HVA22	-	no_errors	REEP5	HGNC	ENSG00000129625	tier1	-	-	81	0	0.00	71	65	47.79	80	0	0.00	29	33	53.23
TARBP1	0	genome.wustl.edu	37	1	234528283	234528283	+	Missense_Mutation	SNP	G	G	T			TCGA-HB-A3L4-01A-11D-A21Q-09	TCGA-HB-A3L4-10A-01D-A21Q-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	23976ad7-4b4a-48ec-b407-36fd75119645	6bdcbf01-b44e-4688-8d32-1892a63a3d28	1	234528283	234528283	G	T	SNP	TARBP1	ENST00000040877	human	ensembl	74_37	-1	novel	missense	c.4576	p.L1526I	1.000	pfam_SpoU_MeTrfase	pfam_SpoU_MeTrfase,superfamily_ARM-type_fold	-	no_errors	TARBP1	HGNC	ENSG00000059588	tier1	-	-	43	0	0.00	38	17	30.91	87	1	1.14	57	21	26.92
PTGFRN	0	genome.wustl.edu	37	1	117509804	117509804	+	Silent	SNP	G	G	A			TCGA-HB-A3L4-01A-11D-A21Q-09	TCGA-HB-A3L4-10A-01D-A21Q-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	23976ad7-4b4a-48ec-b407-36fd75119645	6bdcbf01-b44e-4688-8d32-1892a63a3d28	1	117509804	117509804	G	A	SNP	PTGFRN	ENST00000393203	human	ensembl	74_37	+1	known	silent	c.1911	p.E637	0.984	smart_Ig_sub	pfam_Ig_V-set,smart_Ig_sub,smart_Ig_V-set_subgr,pfscan_Ig-like_dom	-	no_errors	PTGFRN	HGNC	ENSG00000134247	tier1	-	-	13	0	0.00	6	7	53.85	99	0	0.00	39	16	29.09
SLC5A11	0	genome.wustl.edu	37	16	24918471	24918471	+	Nonsense_Mutation	SNP	G	G	T			TCGA-HB-A3L4-01A-11D-A21Q-09	TCGA-HB-A3L4-10A-01D-A21Q-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	23976ad7-4b4a-48ec-b407-36fd75119645	6bdcbf01-b44e-4688-8d32-1892a63a3d28	16	24918471	24918471	G	T	SNP	SLC5A11	ENST00000347898	human	ensembl	74_37	+1	known	nonsense	c.1240	p.E414*	1.000	pfam_Na/solute_symporter,pfscan_Na/solute_symporter,tigrfam_Na/solute_symporter_subgr	pfam_Na/solute_symporter,pfscan_Na/solute_symporter,tigrfam_Na/solute_symporter_subgr	-	no_errors	SLC5A11	HGNC	ENSG00000158865	tier1	-	-	26	0	0.00	35	25	41.67	44	0	0.00	16	17	51.52
SNX25	0	genome.wustl.edu	37	4	186180114	186180114	+	Silent	SNP	G	G	A			TCGA-HB-A3L4-01A-11D-A21Q-09	TCGA-HB-A3L4-10A-01D-A21Q-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	23976ad7-4b4a-48ec-b407-36fd75119645	6bdcbf01-b44e-4688-8d32-1892a63a3d28	4	186180114	186180114	G	A	SNP	SNX25	ENST00000264694	human	ensembl	74_37	+1	known	silent	c.135	p.Q45	1.000	pfam_Phox_assoc,smart_PX_assoc_Snx13,pfscan_Phox_assoc	pfam_Phox_assoc,pfam_Sorting_nexin_C,pfam_RGS_dom,pfam_Phox,superfamily_Regulat_G_prot_signal_superfam,superfamily_Phox,smart_PX_assoc_Snx13,smart_Regulat_G_prot_signal_superfam,smart_Phox,pfscan_Phox,pfscan_Phox_assoc,pfscan_Regulat_G_prot_signal_superfam	-	no_errors	SNX25	HGNC	ENSG00000109762	tier1	-	-	55	0	0.00	42	27	39.13	92	0	0.00	22	10	31.25
LHPP	0	genome.wustl.edu	37	10	126177109	126177109	+	Missense_Mutation	SNP	G	G	C			TCGA-HB-A3L4-01A-11D-A21Q-09	TCGA-HB-A3L4-10A-01D-A21Q-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	23976ad7-4b4a-48ec-b407-36fd75119645	6bdcbf01-b44e-4688-8d32-1892a63a3d28	10	126177109	126177109	G	C	SNP	LHPP	ENST00000368842	human	ensembl	74_37	+1	known	missense	c.432	p.E144D	1.000	pfam_HAD-like_dom,superfamily_HAD-like_dom,tigrfam_HAD-SF_hydro_IIA_hyp2,tigrfam_HAD-SF_hydro_IIA	pfam_HAD-like_dom,superfamily_HAD-like_dom,tigrfam_HAD-SF_hydro_IIA_hyp2,tigrfam_HAD-SF_hydro_IIA	-	no_errors	LHPP	HGNC	ENSG00000107902	tier1	-	-	43	0	0.00	26	27	50.94	60	0	0.00	19	22	53.66
ENSG00000224505	0	genome.wustl.edu	37	17	43227864	43227864	+	R	SNP	G	G	T			TCGA-HB-A3L4-01A-11D-A21Q-09	TCGA-HB-A3L4-10A-01D-A21Q-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	23976ad7-4b4a-48ec-b407-36fd75119645	6bdcbf01-b44e-4688-8d32-1892a63a3d28	17	43227864	43227864	G	T	SNP	ENSG00000224505	ENST00000589950	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.051	-	-	-	no_errors	AC002117.1	Clone_based_vega_gene	ENSG00000224505	tier1	-	-	39	0	0.00	34	18	34.62	89	0	0.00	49	39	44.32
GMPR2	0	genome.wustl.edu	37	14	24707611	24707611	+	Missense_Mutation	SNP	G	G	A			TCGA-HB-A3L4-01A-11D-A21Q-09	TCGA-HB-A3L4-10A-01D-A21Q-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	23976ad7-4b4a-48ec-b407-36fd75119645	6bdcbf01-b44e-4688-8d32-1892a63a3d28	14	24707611	24707611	G	A	SNP	GMPR2	ENST00000348719	human	ensembl	74_37	+1	known	missense	c.857	p.R286K	1.000	tigrfam_GMP_reduct1	pfam_IMP_DH_GMPRt,pfam_FMN-dep_DH,tigrfam_GMP_reduct1	-	no_errors	GMPR2	HGNC	ENSG00000100938	tier1	-	-	20	0	0.00	11	16	59.26	86	0	0.00	18	33	64.71
TMEM255B	0	genome.wustl.edu	37	13	114502418	114502418	+	R	SNP	T	T	C			TCGA-HB-A3L4-01A-11D-A21Q-09	TCGA-HB-A3L4-10A-01D-A21Q-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	23976ad7-4b4a-48ec-b407-36fd75119645	6bdcbf01-b44e-4688-8d32-1892a63a3d28	13	114502418	114502418	T	C	SNP	TMEM255B	ENST00000488362	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	TMEM255B	HGNC	ENSG00000184497	tier1	-	-	32	0	0.00	24	18	42.86	46	0	0.00	18	11	37.93
ELAC2	0	genome.wustl.edu	37	17	12917814	12917814	+	Splice_Site	SNP	C	C	G			TCGA-HB-A3L4-01A-11D-A21Q-09	TCGA-HB-A3L4-10A-01D-A21Q-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	23976ad7-4b4a-48ec-b407-36fd75119645	6bdcbf01-b44e-4688-8d32-1892a63a3d28	17	12917814	12917814	C	G	SNP	ELAC2	ENST00000338034	human	ensembl	74_37	-1	known	splice_site	c.433-1	e5-1	1.000	-	-	-	no_errors	ELAC2	HGNC	ENSG00000006744	tier1	-	-	27	0	0.00	55	27	32.93	84	0	0.00	67	25	27.17
SOS2	0	genome.wustl.edu	37	14	50585356	50585356	+	Silent	SNP	C	C	T			TCGA-HB-A3L4-01A-11D-A21Q-09	TCGA-HB-A3L4-10A-01D-A21Q-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	23976ad7-4b4a-48ec-b407-36fd75119645	6bdcbf01-b44e-4688-8d32-1892a63a3d28	14	50585356	50585356	C	T	SNP	SOS2	ENST00000216373	human	ensembl	74_37	-1	known	silent	c.3705	p.Q1235	1.000	NULL	pfam_RasGRF_CDC25,pfam_Ras-like_Gua-exchang_fac_N,pfam_DH-domain,pfam_Pleckstrin_homology,pfam_Histone_core_D,superfamily_Ras_GEF_dom,superfamily_Histone-fold,superfamily_DH-domain,smart_DH-domain,smart_Pleckstrin_homology,smart_Ras-like_Gua-exchang_fac_N,smart_RasGRF_CDC25,pfscan_Pleckstrin_homology,pfscan_DH-domain,pfscan_RasGRF_CDC25,pfscan_Ras-like_Gua-exchang_fac_N	-	no_errors	SOS2	HGNC	ENSG00000100485	tier1	-	-	72	0	0.00	63	40	38.83	91	0	0.00	29	14	31.82
TRPC5	0	genome.wustl.edu	37	X	111078203	111078203	+	Silent	SNP	T	T	G			TCGA-HB-A3L4-01A-11D-A21Q-09	TCGA-HB-A3L4-10A-01D-A21Q-09	T	T	T	G	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	23976ad7-4b4a-48ec-b407-36fd75119645	6bdcbf01-b44e-4688-8d32-1892a63a3d28	X	111078203	111078203	T	G	SNP	TRPC5	ENST00000262839	human	ensembl	74_37	-1	known	silent	c.1842	p.V614	0.997	pfam_Ion_trans_dom,prints_TRPC_channel,tigrfam_TRP_channel	pfam_Ion_trans_dom,pfam_TRP_dom,superfamily_Ankyrin_rpt-contain_dom,smart_Ankyrin_rpt,prints_TRPC5_channel,prints_TRPC_channel,tigrfam_TRP_channel	-	no_errors	TRPC5	HGNC	ENSG00000072315	tier1	-	-	56	0	0.00	49	44	47.31	101	0	0.00	28	23	45.10
ADNP2	0	genome.wustl.edu	37	18	77895236	77895236	+	Missense_Mutation	SNP	G	G	A			TCGA-HB-A3L4-01A-11D-A21Q-09	TCGA-HB-A3L4-10A-01D-A21Q-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	23976ad7-4b4a-48ec-b407-36fd75119645	6bdcbf01-b44e-4688-8d32-1892a63a3d28	18	77895236	77895236	G	A	SNP	ADNP2	ENST00000262198	human	ensembl	74_37	+1	known	missense	c.1940	p.G647D	0.121	NULL	superfamily_Homeodomain-like,smart_Znf_C2H2-like,smart_Homeobox_dom,pfscan_Znf_C2H2	-	no_errors	ADNP2	HGNC	ENSG00000101544	tier1	-	-	31	0	0.00	19	18	48.65	7	0	0.00	10	5	33.33
ARAP2	0	genome.wustl.edu	37	4	36230792	36230792	+	Missense_Mutation	SNP	A	A	T			TCGA-HB-A3L4-01A-11D-A21Q-09	TCGA-HB-A3L4-10A-01D-A21Q-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	23976ad7-4b4a-48ec-b407-36fd75119645	6bdcbf01-b44e-4688-8d32-1892a63a3d28	4	36230792	36230792	A	T	SNP	ARAP2	ENST00000303965	human	ensembl	74_37	-1	known	missense	c.317	p.L106H	0.000	NULL	pfam_RhoGAP_dom,pfam_Pleckstrin_homology,pfam_ArfGAP,pfam_SAM_type1,pfam_SAM_2,pfam_Ras-assoc,superfamily_Rho_GTPase_activation_prot,superfamily_SAM/pointed,smart_SAM,smart_Pleckstrin_homology,smart_ArfGAP,smart_RhoGAP_dom,pfscan_Pleckstrin_homology,pfscan_Ras-assoc,pfscan_SAM,pfscan_ArfGAP,pfscan_RhoGAP_dom,prints_ArfGAP	-	no_errors	ARAP2	HGNC	ENSG00000047365	tier1	-	-	44	0	0.00	25	19	43.18	98	0	0.00	35	20	36.36
CCDC168	0	genome.wustl.edu	37	13	103382411	103382411	+	Missense_Mutation	SNP	A	A	C			TCGA-HB-A3L4-01A-11D-A21Q-09	TCGA-HB-A3L4-10A-01D-A21Q-09	A	A	A	C	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	23976ad7-4b4a-48ec-b407-36fd75119645	6bdcbf01-b44e-4688-8d32-1892a63a3d28	13	103382411	103382411	A	C	SNP	CCDC168	ENST00000322527	human	ensembl	74_37	-1	known	missense	c.6749	p.L2250W	0.000	NULL	NULL	-	no_errors	CCDC168	HGNC	ENSG00000175820	tier1	-	-	27	0	0.00	14	28	66.67	79	0	0.00	30	18	37.50
SSX7	0	genome.wustl.edu	37	X	52682511	52682511	+	Silent	SNP	G	G	A			TCGA-HB-A3L4-01A-11D-A21Q-09	TCGA-HB-A3L4-10A-01D-A21Q-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	23976ad7-4b4a-48ec-b407-36fd75119645	6bdcbf01-b44e-4688-8d32-1892a63a3d28	X	52682511	52682511	G	A	SNP	SSX7	ENST00000298181	human	ensembl	74_37	-1	known	silent	c.12	p.D4	0.001	NULL	pfam_SSXRD_motif,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,pfscan_Krueppel-associated_box-rel	-	no_errors	SSX7	HGNC	ENSG00000187754	tier1	-	-	261	0	0.00	328	144	30.44	35	0	0.00	16	7	30.43
ARMCX6	0	genome.wustl.edu	37	X	100871412	100871412	+	Missense_Mutation	SNP	G	G	A			TCGA-HB-A3L4-01A-11D-A21Q-09	TCGA-HB-A3L4-10A-01D-A21Q-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	23976ad7-4b4a-48ec-b407-36fd75119645	6bdcbf01-b44e-4688-8d32-1892a63a3d28	X	100871412	100871412	G	A	SNP	ARMCX6	ENST00000361910	human	ensembl	74_37	-1	known	missense	c.199	p.R67W	0.979	NULL	pfam_ARM-rpt_dom	-	no_errors	ARMCX6	HGNC	ENSG00000198960	tier1	rs138992392	-	82	0	0.00	38	50	56.82	96	0	0.00	28	24	46.15
PADI1	0	genome.wustl.edu	37	1	17567209	17567209	+	Missense_Mutation	SNP	T	T	A			TCGA-HB-A3L4-01A-11D-A21Q-09	TCGA-HB-A3L4-10A-01D-A21Q-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	23976ad7-4b4a-48ec-b407-36fd75119645	6bdcbf01-b44e-4688-8d32-1892a63a3d28	1	17567209	17567209	T	A	SNP	PADI1	ENST00000375471	human	ensembl	74_37	+1	known	missense	c.1712	p.L571H	1.000	pfam_PAD_C,pirsf_Protein-arginine_deiminase_sub	pfam_PAD_C,pfam_Prot_Arg_deaminase_cen_dom,pfam_PAD_N,superfamily_Prot_Arg_deaminase_cen_dom,superfamily_Cupredoxin,pirsf_Protein-arginine_deiminase_sub	-	no_errors	PADI1	HGNC	ENSG00000142623	tier1	-	-	56	0	0.00	55	23	29.49	87	0	0.00	34	23	40.35
IFNL2	0	genome.wustl.edu	37	19	39760617	39760617	+	Missense_Mutation	SNP	C	C	A			TCGA-HB-A3L4-01A-11D-A21Q-09	TCGA-HB-A3L4-10A-01D-A21Q-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	23976ad7-4b4a-48ec-b407-36fd75119645	6bdcbf01-b44e-4688-8d32-1892a63a3d28	19	39760617	39760617	C	A	SNP	IFNL2	ENST00000331982	human	ensembl	74_37	+1	known	missense	c.567	p.D189E	0.397	NULL	NULL	-	no_errors	IFNL2	HGNC	ENSG00000183709	tier1	-	-	64	0	0.00	63	32	33.68	67	0	0.00	23	27	54.00
OBSCN	0	genome.wustl.edu	37	1	228494695	228494696	+	Frame_Shift_Ins	INS	-	-	GAGCGTG			TCGA-HB-A3L4-01A-11D-A21Q-09	TCGA-HB-A3L4-10A-01D-A21Q-09	-	-	-	GAGCGTG	-	-	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	23976ad7-4b4a-48ec-b407-36fd75119645	6bdcbf01-b44e-4688-8d32-1892a63a3d28	1	228494695	228494696	-	GAGCGTG	INS	OBSCN	ENST00000422127	human	ensembl	74_37	+1	known	frame_shift_ins	c.12020_12021	p.E4011fs	0.001:0.000	pfam_Ig_I-set,smart_Ig_sub,smart_Ig_sub2,pfscan_Ig-like_dom	pfam_Ig_I-set,pfam_Immunoglobulin,pfam_Ig_V-set,pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Fibronectin_type3,pfam_DH-domain,pfam_IQ_motif_EF-hand-BS,superfamily_Kinase-like_dom,superfamily_DH-domain,superfamily_Fibronectin_type3,superfamily_SH3_domain,smart_Ig_sub,smart_Ig_sub2,smart_Ig_V-set_subgr,smart_Fibronectin_type3,smart_IQ_motif_EF-hand-BS,smart_DH-domain,smart_Pleckstrin_homology,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Fibronectin_type3,pfscan_IQ_motif_EF-hand-BS,pfscan_Pleckstrin_homology,pfscan_Prot_kinase_dom,pfscan_Ig-like_dom,pfscan_DH-domain	-	no_errors	OBSCN	HGNC	ENSG00000154358	tier1			20	0	0.00	12	3	20.00	20	0	0.00	12	3	20.00
SRF	0	genome.wustl.edu	37	6	43143452	43143453	+	Frame_Shift_Del	DEL	GA	GA	-			TCGA-HB-A3L4-01A-11D-A21Q-09	TCGA-HB-A3L4-10A-01D-A21Q-09	GA	GA	GA	-	GA	GA	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	23976ad7-4b4a-48ec-b407-36fd75119645	6bdcbf01-b44e-4688-8d32-1892a63a3d28	6	43143452	43143453	GA	-	DEL	SRF	ENST00000265354	human	ensembl	74_37	+1	known	frame_shift_del	c.789_790	p.K264fs	1.000:1.000	NULL	pfam_TF_MADSbox,superfamily_TF_MADSbox,smart_TF_MADSbox,pfscan_TF_MADSbox,prints_TF_MADSbox	-	no_errors	SRF	HGNC	ENSG00000112658	tier1			37	0	0.00	20	17	45.95	74	0	0.00	29	6	17.14
SRF	0	genome.wustl.edu	37	6	43143443	43143450	+	Frame_Shift_Del	DEL	GGACACAC	GGACACAC	-			TCGA-HB-A3L4-01A-11D-A21Q-09	TCGA-HB-A3L4-10A-01D-A21Q-09	GGACACAC	GGACACAC	GGACACAC	-	GGACACAC	GGACACAC	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	23976ad7-4b4a-48ec-b407-36fd75119645	6bdcbf01-b44e-4688-8d32-1892a63a3d28	6	43143443	43143450	GGACACAC	-	DEL	SRF	ENST00000265354	human	ensembl	74_37	+1	known	frame_shift_del	c.782_787	p.K261fs	1.000:1.000:1.000:0.809:0.785:0.793:0.701:0.997	NULL	pfam_TF_MADSbox,superfamily_TF_MADSbox,smart_TF_MADSbox,pfscan_TF_MADSbox,prints_TF_MADSbox	-	no_errors	SRF	HGNC	ENSG00000112658	tier1			77	0	0.00	31	6	16.22	77	0	0.00	31	6	16.22
TLN2	0	genome.wustl.edu	37	15	63029075	63029075	+	Splice_Site	DEL	A	A	-			TCGA-HB-A3L4-01A-11D-A21Q-09	TCGA-HB-A3L4-10A-01D-A21Q-09	A	A	A	-	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	23976ad7-4b4a-48ec-b407-36fd75119645	6bdcbf01-b44e-4688-8d32-1892a63a3d28	15	63029075	63029075	A	-	DEL	TLN2	ENST00000306829	human	ensembl	74_37	+1	known	splice_site_del	c.3359-2	e26-2	0.998	-	-	-	no_errors	TLN2	HGNC	ENSG00000171914	tier1			22	0	0.00	23	14	37.84	85	0	0.00	38	23	37.70
LOC152586	0	genome.wustl.edu	37	4	141377825	141377825	+	Frame_Shift_Del	DEL	A	A	-			TCGA-HB-A3L4-01A-11D-A21Q-09	TCGA-HB-A3L4-10A-01D-A21Q-09	A	A	A	-	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	23976ad7-4b4a-48ec-b407-36fd75119645	6bdcbf01-b44e-4688-8d32-1892a63a3d28	4	141377825	141377825	A	-	DEL	LOC152586	ENST00000511113	human	ensembl	74_37	-1	putative	frame_shift_del	c.926	p.L309fs	0.985	pfam_Glyco_transf_54	pfam_Glyco_transf_54	-	no_errors	RP11-542P2.1	Clone_based_vega_gene	ENSG00000205301	tier1			26	0	0.00	21	16	43.24	85	0	0.00	55	27	32.93
FAXC	0	genome.wustl.edu	37	6	99728897	99728905	+	R	DEL	TAAGGCTGC	TAAGGCTGC	-			TCGA-HB-A3L4-01A-11D-A21Q-09	TCGA-HB-A3L4-10A-01D-A21Q-09	TAAGGCTGC	TAAGGCTGC	TAAGGCTGC	-	TAAGGCTGC	TAAGGCTGC	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	23976ad7-4b4a-48ec-b407-36fd75119645	6bdcbf01-b44e-4688-8d32-1892a63a3d28	6	99728897	99728905	TAAGGCTGC	-	DEL	FAXC	ENST00000461803	human	ensembl	74_37	-1	known	rna	NULL	NULL	1.000:1.000:1.000:1.000:1.000:1.000:0.997:0.997:0.919	-	-	-	no_errors	FAXC	HGNC	ENSG00000146267	tier1			79	0	0.00	43	7	14.00	79	0	0.00	43	7	14.00
FZD6	0	genome.wustl.edu	37	8	104342132	104342138	+	Frame_Shift_Del	DEL	GAGAGAG	GAGAGAG	-			TCGA-HB-A3L4-01A-11D-A21Q-09	TCGA-HB-A3L4-10A-01D-A21Q-09	GAGAGAG	GAGAGAG	GAGAGAG	-	GAGAGAG	GAGAGAG	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	23976ad7-4b4a-48ec-b407-36fd75119645	6bdcbf01-b44e-4688-8d32-1892a63a3d28	8	104342132	104342138	GAGAGAG	-	DEL	FZD6	ENST00000358755	human	ensembl	74_37	+1	known	frame_shift_del	c.1791_1797	p.R598fs	0.997:1.000:0.999:0.997:0.998:0.983:0.019	NULL	pfam_Frizzled,pfam_Frizzled_dom,superfamily_Frizzled_dom,smart_Frizzled_dom,pfscan_Frizzled_dom,pfscan_GPCR_2-like,prints_Frizzled	-	no_errors	FZD6	HGNC	ENSG00000164930	tier1			85	0	0.00	36	11	23.40	85	0	0.00	36	11	23.40
APOA4	0	genome.wustl.edu	37	11	116691844	116691844	+	Silent	SNP	G	G	A			TCGA-HB-A3L4-01A-11D-A21Q-09	TCGA-HB-A3L4-10A-01D-A21Q-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	23976ad7-4b4a-48ec-b407-36fd75119645	6bdcbf01-b44e-4688-8d32-1892a63a3d28	11	116691844	116691844	G	A	SNP	APOA4	ENST00000357780	human	ensembl	74_37	-1	known	silent	c.930	p.Y310	0.006	pfam_ApoA1_A4_E	pfam_ApoA1_A4_E	-	no_errors	APOA4	HGNC	ENSG00000110244	tier1	-	-	28	0	0.00	22	15	40.54	58	0	0.00	9	26	74.29
DLGAP1	0	genome.wustl.edu	37	18	3879965	3879965	+	Missense_Mutation	SNP	C	C	A			TCGA-HB-A3L4-01A-11D-A21Q-09	TCGA-HB-A3L4-10A-01D-A21Q-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	23976ad7-4b4a-48ec-b407-36fd75119645	6bdcbf01-b44e-4688-8d32-1892a63a3d28	18	3879965	3879965	C	A	SNP	DLGAP1	ENST00000315677	human	ensembl	74_37	-1	known	missense	c.104	p.S35I	1.000	NULL	pfam_GKAP	-	no_errors	DLGAP1	HGNC	ENSG00000170579	tier1	-	-	141	0	0.00	126	96	43.24	22	0	0.00	9	7	43.75
GABRB1	0	genome.wustl.edu	37	4	47427786	47427786	+	Silent	SNP	C	C	A			TCGA-HB-A3L4-01A-11D-A21Q-09	TCGA-HB-A3L4-10A-01D-A21Q-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	23976ad7-4b4a-48ec-b407-36fd75119645	6bdcbf01-b44e-4688-8d32-1892a63a3d28	4	47427786	47427786	C	A	SNP	GABRB1	ENST00000295454	human	ensembl	74_37	+1	known	silent	c.1176	p.A392	0.996	pfam_Neurotrans-gated_channel_TM,superfamily_Neurotrans-gated_channel_TM,tigrfam_Neur_channel	pfam_Neurotrans-gated_channel_TM,pfam_Neur_chan_lig-bd,superfamily_Neur_chan_lig-bd,superfamily_Neurotrans-gated_channel_TM,prints_GABAA_rcpt,prints_GABAAb_rcpt,prints_Neur_channel,prints_GABBAg_rcpt,tigrfam_Neur_channel	-	no_errors	GABRB1	HGNC	ENSG00000163288	tier1	-	-	33	0	0.00	27	25	48.08	28	0	0.00	3	7	70.00
GLYATL1P2	0	genome.wustl.edu	37	11	58660193	58660193	+	R	SNP	G	G	C			TCGA-HB-A3L4-01A-11D-A21Q-09	TCGA-HB-A3L4-10A-01D-A21Q-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	23976ad7-4b4a-48ec-b407-36fd75119645	6bdcbf01-b44e-4688-8d32-1892a63a3d28	11	58660193	58660193	G	C	SNP	GLYATL1P2	ENST00000529451	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	GLYATL1P2	HGNC	ENSG00000254717	tier1	-	-	31	0	0.00	21	16	43.24	40	0	0.00	5	6	54.55
GPR19	0	genome.wustl.edu	37	12	12815224	12815224	+	Silent	SNP	T	T	C			TCGA-HB-A3L4-01A-11D-A21Q-09	TCGA-HB-A3L4-10A-01D-A21Q-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	23976ad7-4b4a-48ec-b407-36fd75119645	6bdcbf01-b44e-4688-8d32-1892a63a3d28	12	12815224	12815224	T	C	SNP	GPR19	ENST00000332427	human	ensembl	74_37	-1	known	silent	c.159	p.Q53	0.000	NULL	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_GPCR_Rhodpsn	-	no_errors	GPR19	HGNC	ENSG00000183150	tier1	-	-	51	0	0.00	7	82	92.13	137	0	0.00	0	78	100.00
LRIG2	0	genome.wustl.edu	37	1	113616182	113616182	+	Missense_Mutation	SNP	C	C	T			TCGA-HB-A3L4-01A-11D-A21Q-09	TCGA-HB-A3L4-10A-01D-A21Q-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	23976ad7-4b4a-48ec-b407-36fd75119645	6bdcbf01-b44e-4688-8d32-1892a63a3d28	1	113616182	113616182	C	T	SNP	LRIG2	ENST00000361127	human	ensembl	74_37	+1	known	missense	c.154	p.P52S	0.251	NULL	pfam_Ig_I-set,pfam_Leu-rich_rpt,pfam_Immunoglobulin,smart_Leu-rich_rpt_typical-subtyp,smart_Cys-rich_flank_reg_C,smart_Ig_sub,smart_Ig_sub2,pfscan_Ig-like_dom	-	no_errors	LRIG2	HGNC	ENSG00000198799	tier1	-	-	38	0	0.00	29	25	46.30	5	0	0.00	2	2	50.00
PCLO	0	genome.wustl.edu	37	7	82584755	82584755	+	Silent	SNP	C	C	T			TCGA-HB-A3L4-01A-11D-A21Q-09	TCGA-HB-A3L4-10A-01D-A21Q-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	23976ad7-4b4a-48ec-b407-36fd75119645	6bdcbf01-b44e-4688-8d32-1892a63a3d28	7	82584755	82584755	C	T	SNP	PCLO	ENST00000333891	human	ensembl	74_37	-1	known	silent	c.5514	p.P1838	0.608	NULL	pfam_Znf_piccolo,pfam_C2_dom,pfam_PDZ,superfamily_C2_dom,superfamily_PDZ,superfamily_Znf_FYVE_PHD,smart_PDZ,smart_C2_dom,pfscan_C2_dom,pfscan_PDZ	-	no_errors	PCLO	HGNC	ENSG00000186472	tier1	-	-	67	0	0.00	5	37	88.10	102	0	0.00	2	40	95.24
PODN	0	genome.wustl.edu	37	1	53538729	53538729	+	R	SNP	G	G	C			TCGA-HB-A3L4-01A-11D-A21Q-09	TCGA-HB-A3L4-10A-01D-A21Q-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	23976ad7-4b4a-48ec-b407-36fd75119645	6bdcbf01-b44e-4688-8d32-1892a63a3d28	1	53538729	53538729	G	C	SNP	PODN	ENST00000471210	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.240	-	-	-	no_errors	PODN	HGNC	ENSG00000174348	tier1	-	-	15	0	0.00	3	7	70.00	18	0	0.00	4	9	69.23
VSTM2B	0	genome.wustl.edu	37	19	30019367	30019367	+	Missense_Mutation	SNP	A	A	T			TCGA-HB-A3L4-01A-11D-A21Q-09	TCGA-HB-A3L4-10A-01D-A21Q-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	23976ad7-4b4a-48ec-b407-36fd75119645	6bdcbf01-b44e-4688-8d32-1892a63a3d28	19	30019367	30019367	A	T	SNP	VSTM2B	ENST00000335523	human	ensembl	74_37	+1	known	missense	c.295	p.S99C	1.000	pfam_Ig_V-set,pfam_Ig_I-set,smart_Ig_sub,pfscan_Ig-like_dom	pfam_Ig_V-set,pfam_Ig_I-set,smart_Ig_sub,pfscan_Ig-like_dom	-	no_errors	VSTM2B	HGNC	ENSG00000187135	tier1	-	-	40	0	0.00	29	25	46.30	34	0	0.00	5	15	75.00
GLIS1	0	genome.wustl.edu	37	1	53986357	53986357	+	Missense_Mutation	SNP	G	G	T			TCGA-HB-A3L4-01A-11D-A21Q-09	TCGA-HB-A3L4-10A-01D-A21Q-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	23976ad7-4b4a-48ec-b407-36fd75119645	6bdcbf01-b44e-4688-8d32-1892a63a3d28	1	53986357	53986357	G	T	SNP	GLIS1	ENST00000312233	human	ensembl	74_37	-1	known	missense	c.1151	p.A384D	0.019	NULL	smart_Znf_C2H2-like,pfscan_Znf_C2H2	-	no_errors	GLIS1	HGNC	ENSG00000174332	tier1	-	-	45	0	0.00	44	4	8.33	3	0	0.00	5	0	0.00
HNRNPA1L2	0	genome.wustl.edu	37	13	53217551	53217553	+	In_Frame_Del	DEL	CAG	CAG	-			TCGA-HB-A3L4-01A-11D-A21Q-09	TCGA-HB-A3L4-10A-01D-A21Q-09	CAG	CAG					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	23976ad7-4b4a-48ec-b407-36fd75119645	6bdcbf01-b44e-4688-8d32-1892a63a3d28	13	53217551	53217553	CAG	-	DEL	HNRNPA1L2	ENST00000342657	human	ensembl	74_37	+1	known	in_frame_del	c.924_926	p.S312in_frame_del	0.015:0.792:0.834	NULL	pfam_RRM_dom,pfam_HnRNPA1,smart_RRM_dom,pfscan_RRM_dom	-	no_errors	HNRNPA1L2	HGNC	ENSG00000139675	tier1			19	0	0.00	17	3	15.00	0	0	0.00	0	0	0.00
LOC644794	0	genome.wustl.edu	37	7	66369212	66369213	+	R	INS	-	-	GGCCTTTCCAGGCCCAGCTCTCGCCTCCCGGC			TCGA-HB-A3L4-01A-11D-A21Q-09	TCGA-HB-A3L4-10A-01D-A21Q-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	23976ad7-4b4a-48ec-b407-36fd75119645	6bdcbf01-b44e-4688-8d32-1892a63a3d28	7	66369212	66369213	-	GGCCTTTCCAGGCCCAGCTCTCGCCTCCCGGC	INS	LOC644794	ENST00000610177	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.293:0.454	-	-	-	no_errors	RP11-458F8.4	Clone_based_vega_gene	ENSG00000273142	tier1			0	0	0.00	1	0	0.00	0	0	0.00	1	0	0.00
KCNK15	0	genome.wustl.edu	37	20	43378937	43378937	+	Missense_Mutation	SNP	T	T	G			TCGA-HB-A3L4-01A-11D-A21Q-09	TCGA-HB-A3L4-10A-01D-A21Q-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	23976ad7-4b4a-48ec-b407-36fd75119645	6bdcbf01-b44e-4688-8d32-1892a63a3d28	20	43378937	43378937	T	G	SNP	KCNK15	ENST00000372861	human	ensembl	74_37	+1	known	missense	c.451	p.W151G	0.980	pirsf_2pore_dom_K_chnl_TASK	pfam_2pore_dom_K_chnl_dom,pirsf_2pore_dom_K_chnl_TASK,prints_TASK5,prints_2pore_dom_K_chnl_TASK,prints_2pore_dom_K_chnl	-	no_errors	KCNK15	HGNC	ENSG00000124249	tier1	-	-	40	0	0.00	24	15	38.46	3	0	0.00	2	2	50.00
ATRX	0	genome.wustl.edu	37	X	76875887	76875887	+	Missense_Mutation	SNP	G	G	C			TCGA-HB-A3L4-01A-11D-A21Q-09	TCGA-HB-A3L4-10A-01D-A21Q-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	23976ad7-4b4a-48ec-b407-36fd75119645	6bdcbf01-b44e-4688-8d32-1892a63a3d28	X	76875887	76875887	G	C	SNP	ATRX	ENST00000373344	human	ensembl	74_37	-1	known	missense	c.5248	p.P1750A	1.000	pfam_SNF2_N,superfamily_P-loop_NTPase,smart_Helicase_ATP-bd,pfscan_Helicase_ATP-bd	pfam_SNF2_N,pfam_Helicase_C,superfamily_P-loop_NTPase,superfamily_Znf_FYVE_PHD,smart_Helicase_ATP-bd,smart_Helicase_C,pfscan_Helicase_ATP-bd,pfscan_Helicase_C	-	no_errors	ATRX	HGNC	ENSG00000085224	tier1	-	-	70	0	0.00	77	18	18.95	72	0	0.00	43	2	4.44
ATRX	0	genome.wustl.edu	37	X	76875886	76875886	+	Missense_Mutation	SNP	G	G	C			TCGA-HB-A3L4-01A-11D-A21Q-09	TCGA-HB-A3L4-10A-01D-A21Q-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	23976ad7-4b4a-48ec-b407-36fd75119645	6bdcbf01-b44e-4688-8d32-1892a63a3d28	X	76875886	76875886	G	C	SNP	ATRX	ENST00000373344	human	ensembl	74_37	-1	known	missense	c.5249	p.P1750R	1.000	pfam_SNF2_N,superfamily_P-loop_NTPase,smart_Helicase_ATP-bd,pfscan_Helicase_ATP-bd	pfam_SNF2_N,pfam_Helicase_C,superfamily_P-loop_NTPase,superfamily_Znf_FYVE_PHD,smart_Helicase_ATP-bd,smart_Helicase_C,pfscan_Helicase_ATP-bd,pfscan_Helicase_C	-	no_errors	ATRX	HGNC	ENSG00000085224	tier1	-	-	70	0	0.00	77	18	18.95	72	0	0.00	43	2	4.44
VPS45	0	genome.wustl.edu	37	1	150082514	150082514	+	R	DEL	A	A	-			TCGA-HB-A3L4-01A-11D-A21Q-09	TCGA-HB-A3L4-10A-01D-A21Q-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	23976ad7-4b4a-48ec-b407-36fd75119645	6bdcbf01-b44e-4688-8d32-1892a63a3d28	1	150082514	150082514	A	-	DEL	VPS45	ENST00000484306	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.965	-	-	-	no_errors	VPS45	HGNC	ENSG00000136631	tier1			16	0	0.00	12	3	20.00	40	0	0.00	22	2	8.33
PTHLH	0	genome.wustl.edu	37	12	28114898	28114898	+	Frame_Shift_Del	DEL	T	T	-			TCGA-HB-A3L4-01A-11D-A21Q-09	TCGA-HB-A3L4-10A-01D-A21Q-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	23976ad7-4b4a-48ec-b407-36fd75119645	6bdcbf01-b44e-4688-8d32-1892a63a3d28	12	28114898	28114898	T	-	DEL	PTHLH	ENST00000354417	human	ensembl	74_37	-1	known	frame_shift_del	c.557	p.K186fs	0.135	NULL	pfam_PTH/PTH-rel,smart_PTH/PTH-rel	-	no_errors	PTHLH	HGNC	ENSG00000087494	tier1			13	0	0.00	18	4	18.18	23	0	0.00	35	3	7.89
ATRX	0	genome.wustl.edu	37	X	76875878	76875884	+	Frame_Shift_Del	DEL	TTTGAAG	TTTGAAG	-			TCGA-HB-A3L4-01A-11D-A21Q-09	TCGA-HB-A3L4-10A-01D-A21Q-09	TTTGAAG	TTTGAAG					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	23976ad7-4b4a-48ec-b407-36fd75119645	6bdcbf01-b44e-4688-8d32-1892a63a3d28	X	76875878	76875884	TTTGAAG	-	DEL	ATRX	ENST00000373344	human	ensembl	74_37	-1	known	frame_shift_del	c.5257_5251	p.L1751fs	1.000:0.987:1.000:1.000:1.000:1.000:0.999	pfam_SNF2_N,superfamily_P-loop_NTPase,smart_Helicase_ATP-bd,pfscan_Helicase_ATP-bd	pfam_SNF2_N,pfam_Helicase_C,superfamily_P-loop_NTPase,superfamily_Znf_FYVE_PHD,smart_Helicase_ATP-bd,smart_Helicase_C,pfscan_Helicase_ATP-bd,pfscan_Helicase_C	-	no_errors	ATRX	HGNC	ENSG00000085224	tier1			69	0	0.00	42	2	4.55	69	0	0.00	42	2	4.55