Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	default_gene_name	gene_name_source	 ensembl_gene_id	tier	dbSNP	GMAF	n_ref_count	n_alt_count	normal_vaf	t_ref_count	t_alt_count	tumor_vaf	n_ref_count_val	n_alt_count_val	normal_vaf_val	t_ref_count_val	t_alt_count_val	tumor_vaf_val
SUV39H1	0	genome.wustl.edu	37	X	48559061	48559061	+	Missense_Mutation	SNP	C	C	T			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	X	48559061	48559061	C	T	SNP	SUV39H1	ENST00000337852	human	ensembl	74_37	+1	known	missense	c.778	p.R260C	1.000	smart_SET_dom,pirsf_Histone_H3-K9_MeTrfase,pfscan_SET_dom	pfam_SET_dom,pfam_Pre-SET_dom,pfam_Chromo_domain,superfamily_Chromodomain-like,smart_Chromo_domain/shadow,smart_Pre-SET_Zn-bd_sub,smart_SET_dom,smart_Post-SET_dom,pirsf_Histone_H3-K9_MeTrfase,pfscan_SET_dom,pfscan_Pre-SET_dom,pfscan_Post-SET_dom,pfscan_Chromo_domain/shadow	-	no_errors	SUV39H1	HGNC	ENSG00000101945	tier1	-	-	121	0	0.00	23	45	66.18	66	1	1.49	20	39	66.10
CDH12	0	genome.wustl.edu	37	5	22212547	22212547	+	R	SNP	T	T	C			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	5	22212547	22212547	T	C	SNP	CDH12	ENST00000518209	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.882	-	-	-	no_errors	CDH12	HGNC	ENSG00000154162	tier1	-	-	13	0	0.00	14	7	33.33	41	0	0.00	45	31	40.79
GPR98	0	genome.wustl.edu	37	5	90136405	90136405	+	Missense_Mutation	SNP	G	G	T			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	5	90136405	90136405	G	T	SNP	GPR98	ENST00000405460	human	ensembl	74_37	+1	known	missense	c.16622	p.S5541I	0.432	NULL	pfam_Calx_beta,pfam_EPTP,pfam_GPCR_2_secretin-like,pfam_GPS_dom,superfamily_ConA-like_lec_gl_sf,superfamily_Gal_Oxase/kelch_b-propeller,smart_Calx_beta,pfscan_EAR,pfscan_GPS_dom,pfscan_GPCR_2-like	-	no_errors	GPR98	HGNC	ENSG00000164199	tier1	-	-	77	0	0.00	25	21	45.65	85	0	0.00	84	40	32.26
FRYL	0	genome.wustl.edu	37	4	48588694	48588694	+	Silent	SNP	A	A	T			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	4	48588694	48588694	A	T	SNP	FRYL	ENST00000358350	human	ensembl	74_37	-1	known	silent	c.1692	p.I564	1.000	superfamily_ARM-type_fold	superfamily_ARM-type_fold	-	no_errors	FRYL	HGNC	ENSG00000075539	tier1	-	-	41	0	0.00	21	7	25.00	100	0	0.00	84	25	22.94
OR10AG1	0	genome.wustl.edu	37	11	55735654	55735654	+	Missense_Mutation	SNP	G	G	A			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	11	55735654	55735654	G	A	SNP	OR10AG1	ENST00000312345	human	ensembl	74_37	-1	known	missense	c.286	p.L96F	0.000	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_GPCR_Rhodpsn	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR10AG1	HGNC	ENSG00000174970	tier1	-	-	39	0	0.00	9	34	79.07	53	0	0.00	18	31	63.27
OR4C5	0	genome.wustl.edu	37	11	48387367	48387367	+	Silent	SNP	T	T	C			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	11	48387367	48387367	T	C	SNP	OR4C5	ENST00000319813	human	ensembl	74_37	-1	known	silent	c.651	p.G217	0.069	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR4C5	HGNC	ENSG00000176540	tier1	-	-	43	0	0.00	22	14	38.89	113	0	0.00	63	70	52.24
MCF2L	0	genome.wustl.edu	37	13	113563587	113563587	+	Missense_Mutation	SNP	C	C	G			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	13	113563587	113563587	C	G	SNP	MCF2L	ENST00000397036	human	ensembl	74_37	+1	putative	missense	c.190	p.Q64E	0.000	NULL	NULL	-	no_errors	MCF2L	HGNC	ENSG00000126217	tier1	-	-	45	0	0.00	12	21	63.64	63	0	0.00	12	19	61.29
CHR4	0	genome.wustl.edu	37	20	61982158	61982158	+	Missense_Mutation	SNP	T	T	A			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	20	61982158	61982158	T	A	SNP	CHR4	ENST00000370263	human	ensembl	74_37	-1	known	missense	c.605	p.D202V	1.000	pfam_Neur_chan_lig-bd,superfamily_Neur_chan_lig-bd,tigrfam_Neur_channel	pfam_Neurotrans-gated_channel_TM,pfam_Neur_chan_lig-bd,superfamily_Neurotrans-gated_channel_TM,superfamily_Neur_chan_lig-bd,prints_Nicotinic_acetylcholine_rcpt,prints_Neur_channel,tigrfam_Neur_channel	-	no_errors	CHR4	HGNC	ENSG00000101204	tier1	-	-	80	0	0.00	29	27	48.21	48	0	0.00	28	32	53.33
FRYL	0	genome.wustl.edu	37	4	48588693	48588693	+	Missense_Mutation	SNP	G	G	A			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	4	48588693	48588693	G	A	SNP	FRYL	ENST00000358350	human	ensembl	74_37	-1	known	missense	c.1693	p.P565S	1.000	superfamily_ARM-type_fold	superfamily_ARM-type_fold	-	no_errors	FRYL	HGNC	ENSG00000075539	tier1	-	-	41	0	0.00	20	8	28.57	100	0	0.00	83	25	23.15
MBD6	0	genome.wustl.edu	37	12	57922286	57922286	+	Missense_Mutation	SNP	A	A	T			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	12	57922286	57922286	A	T	SNP	MBD6	ENST00000355673	human	ensembl	74_37	+1	known	missense	c.2763	p.E921D	1.000	NULL	superfamily_D-bd_dom,smart_Methyl_CpG_D-bd,pfscan_Methyl_CpG_D-bd	-	no_errors	MBD6	HGNC	ENSG00000166987	tier1	-	-	53	0	0.00	40	12	23.08	93	0	0.00	95	20	17.39
LYRM5	0	genome.wustl.edu	37	12	25357129	25357129	+	Missense_Mutation	SNP	C	C	G			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	12	25357129	25357129	C	G	SNP	LYRM5	ENST00000381356	human	ensembl	74_37	+1	known	missense	c.156	p.I52M	1.000	pfam_Complex1_LYR	pfam_Complex1_LYR	-	no_errors	LYRM5	HGNC	ENSG00000205707	tier1	-	-	34	0	0.00	32	23	41.82	71	0	0.00	59	41	41.00
PRKG1	0	genome.wustl.edu	37	10	53841418	53841418	+	Splice_Site	SNP	G	G	T			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	10	53841418	53841418	G	T	SNP	PRKG1	ENST00000373975	human	ensembl	74_37	+1	putative	splice_site	c.44+1	e1+1	0.026	-	-	-	no_errors	PRKG1	HGNC	ENSG00000185532	tier1	-	-	37	0	0.00	11	10	47.62	82	0	0.00	31	58	65.17
PSKH2	0	genome.wustl.edu	37	8	87076845	87076845	+	Silent	SNP	A	A	T			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	8	87076845	87076845	A	T	SNP	PSKH2	ENST00000276616	human	ensembl	74_37	-1	known	silent	c.201	p.A67	1.000	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	-	no_errors	PSKH2	HGNC	ENSG00000147613	tier1	-	-	22	0	0.00	22	4	15.38	47	0	0.00	60	18	23.08
F5	0	genome.wustl.edu	37	1	169509969	169509969	+	Missense_Mutation	SNP	C	C	G			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	1	169509969	169509969	C	G	SNP	F5	ENST00000367797	human	ensembl	74_37	-1	known	missense	c.4359	p.Q1453H	0.017	NULL	pfam_Coagulation_fac_5/8-C_type_dom,pfam_Cu-oxidase_3,superfamily_Galactose-bd-like,superfamily_Cupredoxin,smart_Coagulation_fac_5/8-C_type_dom,pfscan_Coagulation_fac_5/8-C_type_dom	-	no_errors	F5	HGNC	ENSG00000198734	tier1	-	-	44	0	0.00	44	23	34.33	72	0	0.00	95	57	37.50
GOT1L1	0	genome.wustl.edu	37	8	37792593	37792593	+	Missense_Mutation	SNP	T	T	G			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	T	T	T	G	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	8	37792593	37792593	T	G	SNP	GOT1L1	ENST00000307599	human	ensembl	74_37	-1	known	missense	c.1070	p.N357T	0.021	pfam_Aminotransferase_I/II,superfamily_PyrdxlP-dep_Trfase,prints_Asp_trans	pfam_Aminotransferase_I/II,superfamily_PyrdxlP-dep_Trfase,prints_Asp_trans	-	no_errors	GOT1L1	HGNC	ENSG00000169154	tier1	-	-	75	0	0.00	17	19	52.78	82	0	0.00	21	44	67.69
MACF1	0	genome.wustl.edu	37	1	39929473	39929473	+	R	SNP	C	C	A			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	1	39929473	39929473	C	A	SNP	MACF1	ENST00000497964	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	MACF1	HGNC	ENSG00000127603	tier1	-	-	40	0	0.00	13	24	64.86	52	0	0.00	16	46	74.19
HECW1	0	genome.wustl.edu	37	7	43153832	43153832	+	R	SNP	C	C	A			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	7	43153832	43153832	C	A	SNP	HECW1	ENST00000492310	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.166	-	-	-	no_errors	HECW1	HGNC	ENSG00000002746	tier1	-	-	35	0	0.00	7	19	73.08	90	0	0.00	20	47	69.12
NLRP14	0	genome.wustl.edu	37	11	7059832	7059832	+	Silent	SNP	A	A	G			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	11	7059832	7059832	A	G	SNP	NLRP14	ENST00000299481	human	ensembl	74_37	+1	known	silent	c.15	p.S5	0.010	pfscan_DAPIN	pfam_DAPIN,superfamily_DEATH-like_dom,superfamily_P-loop_NTPase,smart_Leu-rich_rpt_RNase_inh_sub-typ,pfscan_CHT_NTPase,pfscan_DAPIN	-	no_errors	NLRP14	HGNC	ENSG00000158077	tier1	-	-	56	0	0.00	12	21	63.64	87	0	0.00	43	75	63.56
TUB	0	genome.wustl.edu	37	11	8122074	8122074	+	Missense_Mutation	SNP	G	G	A			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	11	8122074	8122074	G	A	SNP	TUB	ENST00000305253	human	ensembl	74_37	+1	known	missense	c.1306	p.G436R	1.000	pfam_Tubby_C,superfamily_Tubby_C-like,prints_Tubby_C	pfam_Tubby_C,superfamily_Tubby_C-like,prints_Tubby_N,prints_Tubby_C	-	no_errors	TUB	HGNC	ENSG00000166402	tier1	-	-	45	0	0.00	5	22	81.48	111	0	0.00	25	58	69.88
CDK12	0	genome.wustl.edu	37	17	37672033	37672033	+	Missense_Mutation	SNP	C	C	G			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	17	37672033	37672033	C	G	SNP	CDK12	ENST00000447079	human	ensembl	74_37	+1	known	missense	c.2818	p.L940V	1.000	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	-	no_errors	CDK12	HGNC	ENSG00000167258	tier1	-	-	46	0	0.00	24	9	27.27	92	0	0.00	69	57	44.88
TEX15	0	genome.wustl.edu	37	8	30701918	30701918	+	Missense_Mutation	SNP	C	C	A			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	8	30701918	30701918	C	A	SNP	TEX15	ENST00000256246	human	ensembl	74_37	-1	known	missense	c.4616	p.R1539I	0.000	NULL	NULL	-	no_errors	TEX15	HGNC	ENSG00000133863	tier1	-	-	84	0	0.00	22	35	61.40	100	0	0.00	40	64	60.95
HAUS3	0	genome.wustl.edu	37	4	2237996	2237996	+	Missense_Mutation	SNP	T	T	C			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	4	2237996	2237996	T	C	SNP	HAUS3	ENST00000243706	human	ensembl	74_37	-1	known	missense	c.1537	p.T513A	0.698	NULL	NULL	-	no_errors	HAUS3	HGNC	ENSG00000214367	tier1	-	-	36	0	0.00	30	4	11.76	99	0	0.00	90	40	30.77
TTN	0	genome.wustl.edu	37	2	179560896	179560896	+	Missense_Mutation	SNP	C	C	G			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	2	179560896	179560896	C	G	SNP	TTN	ENST00000342992	human	ensembl	74_37	-1	known	missense	c.27171	p.E9057D	0.998	superfamily_Calpain_domain_III,superfamily_RNaseH-like_dom	pfam_Ig_I-set,pfam_Fibronectin_type3,pfam_Immunoglobulin,pfam_Ig_V-set,pfam_Titin_Z,pfam_PPAK_motif,pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,superfamily_Fibronectin_type3,superfamily_Calpain_domain_III,superfamily_RNaseH-like_dom,smart_Ig_sub,smart_Ig_sub2,smart_Ig_V-set_subgr,smart_Fibronectin_type3,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Fibronectin_type3,pfscan_Prot_kinase_dom,pfscan_Ig-like_dom	-	no_errors	TTN	HGNC	ENSG00000155657	tier1	-	-	122	0	0.00	52	23	30.26	77	0	0.00	45	35	43.75
MTOR	0	genome.wustl.edu	37	1	11174523	11174523	+	R	SNP	C	C	G			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	1	11174523	11174523	C	G	SNP	MTOR	ENST00000473471	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.085	-	-	-	no_errors	MTOR	HGNC	ENSG00000198793	tier1	-	-	44	0	0.00	15	4	21.05	60	0	0.00	54	18	25.00
AATF	0	genome.wustl.edu	37	17	35413995	35413995	+	R	SNP	C	C	A			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	17	35413995	35413995	C	A	SNP	AATF	ENST00000587618	human	ensembl	74_37	+1	putative	rna	NULL	NULL	0.000	-	-	-	no_errors	AATF	HGNC	ENSG00000108270	tier1	-	-	40	0	0.00	17	6	26.09	27	0	0.00	41	13	24.07
PRELP	0	genome.wustl.edu	37	1	203455877	203455877	+	Missense_Mutation	SNP	C	C	A			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	1	203455877	203455877	C	A	SNP	PRELP	ENST00000343110	human	ensembl	74_37	+1	known	missense	c.1017	p.F339L	1.000	NULL	pfam_Leu-rich_rpt,pfam_LRR-contain_N,smart_LRR-contain_N,smart_Leu-rich_rpt_typical-subtyp	-	no_errors	PRELP	HGNC	ENSG00000188783	tier1	-	-	87	0	0.00	49	26	34.67	93	0	0.00	114	66	36.67
C4BPA	0	genome.wustl.edu	37	1	207300183	207300183	+	Missense_Mutation	SNP	G	G	T			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	1	207300183	207300183	G	T	SNP	C4BPA	ENST00000367070	human	ensembl	74_37	+1	known	missense	c.832	p.V278L	0.000	pfam_Sushi_SCR_CCP,superfamily_Sushi_SCR_CCP,smart_Sushi_SCR_CCP,pfscan_Sushi_SCR_CCP	pfam_Sushi_SCR_CCP,superfamily_Sushi_SCR_CCP,smart_Sushi_SCR_CCP,pfscan_Sushi_SCR_CCP	-	no_errors	C4BPA	HGNC	ENSG00000123838	tier1	-	-	38	0	0.00	20	12	37.50	81	0	0.00	88	34	27.87
CRYBG3	0	genome.wustl.edu	37	3	97596769	97596769	+	Missense_Mutation	SNP	C	C	G			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	3	97596769	97596769	C	G	SNP	CRYBG3	ENST00000182096	human	ensembl	74_37	+1	known	missense	c.887	p.S296C	0.943	NULL	pfam_Beta/gamma_crystallin,pfam_Ricin_B_lectin,superfamily_G_crystallin-rel,superfamily_Ricin_B_lectin,smart_Beta/gamma_crystallin,smart_Ricin_B_lectin,pfscan_Ricin_B_lectin,pfscan_Beta/gamma_crystallin,prints_Beta/gamma_crystallin	-	no_errors	CRYBG3	HGNC	ENSG00000080200	tier1	-	-	52	0	0.00	39	8	17.02	68	0	0.00	38	16	29.63
SPECC1	0	genome.wustl.edu	37	17	20150563	20150563	+	Missense_Mutation	SNP	G	G	C			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	17	20150563	20150563	G	C	SNP	SPECC1	ENST00000261503	human	ensembl	74_37	+1	known	missense	c.2529	p.K843N	0.976	NULL	pfam_CH-domain,pfam_CAMSAP_CH,superfamily_CH-domain,smart_CH-domain,pfscan_CH-domain	-	no_errors	SPECC1	HGNC	ENSG00000128487	tier1	-	-	36	0	0.00	24	4	14.29	28	0	0.00	20	4	16.67
TBC1D3P1-DHX40P1	0	genome.wustl.edu	37	17	58094588	58094588	+	R	SNP	T	T	G			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	T	T	T	G	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	17	58094588	58094588	T	G	SNP	TBC1D3P1-DHX40P1	ENST00000407042	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.001	-	-	-	no_errors	TBC1D3P1-DHX40P1	HGNC	ENSG00000267104	tier1	-	-	333	0	0.00	286	83	22.43	48	0	0.00	57	17	22.97
CNGB3	0	genome.wustl.edu	37	8	87616328	87616328	+	Missense_Mutation	SNP	C	C	T			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	8	87616328	87616328	C	T	SNP	CNGB3	ENST00000320005	human	ensembl	74_37	-1	known	missense	c.1774	p.E592K	1.000	pfam_cNMP-bd_dom,superfamily_cNMP-bd-like,smart_cNMP-bd_dom,pfscan_cNMP-bd_dom	pfam_cNMP-bd_dom,superfamily_cNMP-bd-like,smart_cNMP-bd_dom,pfscan_cNMP-bd_dom	-	no_errors	CNGB3	HGNC	ENSG00000170289	tier1	-	-	45	0	0.00	15	15	50.00	79	0	0.00	62	34	35.42
SPTBN1	0	genome.wustl.edu	37	2	54839385	54839385	+	Missense_Mutation	SNP	C	C	G			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	2	54839385	54839385	C	G	SNP	SPTBN1	ENST00000356805	human	ensembl	74_37	+1	known	missense	c.388	p.L130V	1.000	pirsf_Spectrin_bsu,pfam_CH-domain,superfamily_CH-domain,smart_CH-domain,pfscan_CH-domain	pirsf_Spectrin_bsu,pfam_Spectrin_repeat,pfam_CH-domain,pfam_Pleckstrin_homology,pfam_CAMSAP_CH,superfamily_CH-domain,smart_CH-domain,smart_Spectrin/alpha-actinin,smart_Pleckstrin_homology,prints_PH_dom-spectrin-type,pfscan_CH-domain,pfscan_Pleckstrin_homology	-	no_errors	SPTBN1	HGNC	ENSG00000115306	tier1	-	-	93	0	0.00	54	41	43.16	108	0	0.00	114	55	32.54
GALNT3	0	genome.wustl.edu	37	2	166605335	166605335	+	Missense_Mutation	SNP	G	G	T			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	2	166605335	166605335	G	T	SNP	GALNT3	ENST00000392701	human	ensembl	74_37	-1	known	missense	c.1858	p.P620T	1.000	pfam_Ricin_B_lectin,superfamily_Ricin_B_lectin,smart_Ricin_B_lectin,pfscan_Ricin_B_lectin	pfam_Glyco_trans_2,pfam_Ricin_B_lectin,superfamily_Ricin_B_lectin,smart_Ricin_B_lectin,pfscan_Ricin_B_lectin	-	no_errors	GALNT3	HGNC	ENSG00000115339	tier1	-	-	64	0	0.00	37	14	27.45	94	0	0.00	62	21	25.30
TTC6	0	genome.wustl.edu	37	14	38165968	38165968	+	Missense_Mutation	SNP	G	G	A			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	14	38165968	38165968	G	A	SNP	TTC6	ENST00000553443	human	ensembl	74_37	+1	novel	missense	c.1304	p.R435Q	0.022	NULL	pfam_TPR_1,pfam_TPR_2,smart_TPR_repeat,pfscan_TPR_repeat,pfscan_TPR-contain_dom	-	no_errors	TTC6	HGNC	ENSG00000139865	tier1	-	-	37	0	0.00	6	14	70.00	97	0	0.00	35	79	69.30
ROBO4	0	genome.wustl.edu	37	11	124766916	124766916	+	Silent	SNP	G	G	A			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	11	124766916	124766916	G	A	SNP	ROBO4	ENST00000306534	human	ensembl	74_37	-1	known	silent	c.312	p.A104	0.376	pfam_Ig_I-set,smart_Ig_sub,smart_Ig_sub2,pfscan_Ig-like_dom	pfam_Ig_I-set,pfam_Fibronectin_type3,pfam_Immunoglobulin,superfamily_Fibronectin_type3,smart_Ig_sub,smart_Ig_sub2,smart_Fibronectin_type3,pfscan_Fibronectin_type3,pfscan_Ig-like_dom	-	no_errors	ROBO4	HGNC	ENSG00000154133	tier1	-	-	76	0	0.00	42	32	43.24	15	0	0.00	11	4	26.67
SLCO1B1	0	genome.wustl.edu	37	12	21370181	21370181	+	Silent	SNP	C	C	G			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	12	21370181	21370181	C	G	SNP	SLCO1B1	ENST00000256958	human	ensembl	74_37	+1	known	silent	c.1626	p.V542	0.001	pfam_OA_transporter,superfamily_MFS_dom_general_subst_transpt,pfscan_MFS_dom,tigrfam_OA_transporter	pfam_OA_transporter,pfam_MFS,pfam_Kazal_dom,superfamily_MFS_dom_general_subst_transpt,pfscan_MFS_dom,tigrfam_OA_transporter	-	no_errors	SLCO1B1	HGNC	ENSG00000134538	tier1	-	-	47	0	0.00	32	17	34.69	38	0	0.00	47	17	26.56
NRF1	0	genome.wustl.edu	37	7	129367102	129367102	+	Silent	SNP	C	C	G			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	7	129367102	129367102	C	G	SNP	NRF1	ENST00000393231	human	ensembl	74_37	+1	known	silent	c.1245	p.V415	1.000	NULL	pfam_Nrf1_NLS/D-bd_dimer,pfam_Nrf1_activation-bd	-	no_errors	NRF1	HGNC	ENSG00000106459	tier1	-	-	76	0	0.00	46	10	17.86	22	0	0.00	15	2	11.76
GLRA1	0	genome.wustl.edu	37	5	151239459	151239459	+	Silent	SNP	G	G	A			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	5	151239459	151239459	G	A	SNP	GLRA1	ENST00000455880	human	ensembl	74_37	-1	known	silent	c.363	p.I121	1.000	pfam_Neur_chan_lig-bd,superfamily_Neur_chan_lig-bd,prints_Neur_channel,tigrfam_Neur_channel	pfam_Neur_chan_lig-bd,pfam_Neurotrans-gated_channel_TM,superfamily_Neur_chan_lig-bd,superfamily_Neurotrans-gated_channel_TM,prints_GABAA_rcpt,prints_Glycine_rcpt_A,prints_Glycine_rcpt_A1,prints_Neur_channel,tigrfam_Neur_channel	-	no_errors	GLRA1	HGNC	ENSG00000145888	tier1	-	-	104	0	0.00	47	33	41.25	104	0	0.00	51	49	49.00
PLX2	0	genome.wustl.edu	37	1	208390563	208390563	+	Silent	SNP	C	C	G			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	1	208390563	208390563	C	G	SNP	PLX2	ENST00000367033	human	ensembl	74_37	-1	known	silent	c.705	p.L235	0.993	pfam_Semap_dom,superfamily_Semap_dom,smart_Semap_dom,pfscan_Semap_dom	pfam_Plexin_cytoplasmic_RasGAP_dom,pfam_Semap_dom,pfam_IPT,pfam_Plexin_repeat,superfamily_Semap_dom,superfamily_Rho_GTPase_activation_prot,superfamily_Ig_E-set,superfamily_Plexin-like_fold,smart_Semap_dom,smart_Plexin-like_fold,smart_IPT,pfscan_Semap_dom	-	no_errors	PLX2	HGNC	ENSG00000076356	tier1	-	-	60	0	0.00	46	19	29.23	107	1	0.92	106	60	36.14
EIF2S2	0	genome.wustl.edu	37	20	32684518	32684518	+	Missense_Mutation	SNP	C	C	T			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	20	32684518	32684518	C	T	SNP	EIF2S2	ENST00000374980	human	ensembl	74_37	-1	known	missense	c.628	p.V210I	1.000	pfam_Transl_init_fac_IF2/IF5,superfamily_Transl_init_fac_IF2/IF5_N,smart_Transl_init_fac_IF2/IF5	pfam_Transl_init_fac_IF2/IF5,superfamily_Transl_init_fac_IF2/IF5_N,superfamily_Transl_init_fac_IF2/IF5_Zn-bd,smart_Transl_init_fac_IF2/IF5	-	no_errors	EIF2S2	HGNC	ENSG00000125977	tier1	-	-	81	0	0.00	38	24	38.71	56	0	0.00	68	42	37.84
SLC27A5	0	genome.wustl.edu	37	19	59022824	59022824	+	Missense_Mutation	SNP	C	C	T			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	19	59022824	59022824	C	T	SNP	SLC27A5	ENST00000263093	human	ensembl	74_37	-1	known	missense	c.499	p.A167T	0.000	pfam_AMP-dep_Synth/Lig	pfam_AMP-dep_Synth/Lig	-	no_errors	SLC27A5	HGNC	ENSG00000083807	tier1	-	-	58	0	0.00	41	7	14.58	11	0	0.00	11	3	21.43
HDHD3	0	genome.wustl.edu	37	9	116136322	116136322	+	Missense_Mutation	SNP	A	A	C			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	A	A	A	C	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	9	116136322	116136322	A	C	SNP	HDHD3	ENST00000238379	human	ensembl	74_37	-1	known	missense	c.313	p.F105V	1.000	pfam_HAD-like_dom,superfamily_HAD-like_dom,tigrfam_HAD-SF_hydro_IA_REG-2-like	pfam_HAD-like_dom,superfamily_HAD-like_dom,prints_HAD-SF_hydro_IA,tigrfam_HAD-SF_hydro_IA_REG-2-like,tigrfam_HAD-SF_hydro_IA	-	no_errors	HDHD3	HGNC	ENSG00000119431	tier1	-	-	28	0	0.00	14	7	33.33	34	0	0.00	13	2	13.33
ACY1	0	genome.wustl.edu	37	3	52019141	52019141	+	R	SNP	T	T	C			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	3	52019141	52019141	T	C	SNP	ACY1	ENST00000468068	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.001	-	-	-	no_errors	ACY1	HGNC	ENSG00000243989	tier1	-	-	45	0	0.00	14	5	26.32	56	0	0.00	40	6	13.04
HTR3C	0	genome.wustl.edu	37	3	183776224	183776224	+	Missense_Mutation	SNP	T	T	G			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	T	T	T	G	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	3	183776224	183776224	T	G	SNP	HTR3C	ENST00000318351	human	ensembl	74_37	+1	known	missense	c.569	p.M190R	0.037	pfam_Neur_chan_lig-bd,superfamily_Neur_chan_lig-bd	pfam_Neur_chan_lig-bd,pfam_Neurotrans-gated_channel_TM,superfamily_Neur_chan_lig-bd,superfamily_Neurotrans-gated_channel_TM,prints_Neur_channel	-	no_errors	HTR3C	HGNC	ENSG00000178084	tier1	-	-	43	0	0.00	25	15	37.50	55	0	0.00	102	39	27.46
RPS23	0	genome.wustl.edu	37	5	81571946	81571946	+	Missense_Mutation	SNP	C	C	G			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	5	81571946	81571946	C	G	SNP	RPS23	ENST00000296674	human	ensembl	74_37	-1	known	missense	c.414	p.K138N	1.000	pfam_Ribosomal_S12/S23,superfamily_-bd_OB-fold,pirsf_Ribosomal_S12/S23,tigrfam_Ribosomal_S23_euk/arc	pfam_Ribosomal_S12/S23,superfamily_-bd_OB-fold,pirsf_Ribosomal_S12/S23,tigrfam_Ribosomal_S23_euk/arc	-	no_errors	RPS23	HGNC	ENSG00000186468	tier1	-	-	31	0	0.00	29	10	25.64	38	0	0.00	40	17	29.82
FAT2	0	genome.wustl.edu	37	5	150922247	150922247	+	Missense_Mutation	SNP	G	G	A			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	5	150922247	150922247	G	A	SNP	FAT2	ENST00000261800	human	ensembl	74_37	-1	known	missense	c.8441	p.T2814I	0.976	pfam_Cadherin,superfamily_Cadherin-like,pfscan_Cadherin	pfam_Cadherin,pfam_Laminin_G,superfamily_Cadherin-like,superfamily_ConA-like_lec_gl_sf,smart_Cadherin,smart_Laminin_G,smart_EGF-like_Ca-bd_dom,smart_EG-like_dom,pfscan_EG-like_dom,pfscan_Laminin_G,pfscan_Cadherin,prints_Cadherin	-	no_errors	FAT2	HGNC	ENSG00000086570	tier1	-	-	38	0	0.00	17	9	34.62	52	0	0.00	40	16	28.57
ANKRD40	0	genome.wustl.edu	37	17	48773462	48773462	+	Silent	SNP	G	G	A			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	17	48773462	48773462	G	A	SNP	ANKRD40	ENST00000285243	human	ensembl	74_37	-1	known	silent	c.1003	p.L335	1.000	NULL	pfam_Ankyrin_rpt,superfamily_Ankyrin_rpt-contain_dom,smart_Ankyrin_rpt,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom	-	no_errors	ANKRD40	HGNC	ENSG00000154945	tier1	-	-	68	0	0.00	56	17	23.29	87	0	0.00	111	21	15.91
POT1	0	genome.wustl.edu	37	7	124503553	124503553	+	Missense_Mutation	SNP	C	C	T			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	7	124503553	124503553	C	T	SNP	POT1	ENST00000357628	human	ensembl	74_37	-1	known	missense	c.397	p.V133I	1.000	pfam_Telomer_end-bd_POT1/Cdc13,superfamily_-bd_OB-fold,smart_Telomer_end-bd_POT1/Cdc13	pfam_Telomer_end-bd_POT1/Cdc13,superfamily_-bd_OB-fold,smart_Telomer_end-bd_POT1/Cdc13	-	no_errors	POT1	HGNC	ENSG00000128513	tier1	-	-	51	0	0.00	32	19	37.25	84	1	1.18	65	64	49.61
SNHG11	0	genome.wustl.edu	37	20	37075523	37075523	+	R	SNP	G	G	T			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	20	37075523	37075523	G	T	SNP	SNHG11	ENST00000359074	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.149	-	-	-	no_errors	SNHG11	HGNC	ENSG00000174365	tier1	-	-	75	0	0.00	45	34	43.04	45	0	0.00	29	13	30.95
ENSG00000261546	0	genome.wustl.edu	37	16	89181109	89181109	+	R	SNP	G	G	A			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	16	89181109	89181109	G	A	SNP	ENSG00000261546	ENST00000562782	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	CTD-2555A7.3	Clone_based_vega_gene	ENSG00000261546	tier1	-	-	10	0	0.00	3	11	78.57	81	0	0.00	24	62	72.09
TRIO	0	genome.wustl.edu	37	5	14405992	14405992	+	Silent	SNP	G	G	A			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	5	14405992	14405992	G	A	SNP	TRIO	ENST00000344204	human	ensembl	74_37	+1	known	silent	c.4752	p.K1584	1.000	smart_Pleckstrin_homology,pfscan_Pleckstrin_homology	pfam_DH-domain,pfam_Prot_kinase_dom,pfam_Spectrin_repeat,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Ig_I-set,pfam_SH3_domain,superfamily_Kinase-like_dom,superfamily_DH-domain,superfamily_SH3_domain,superfamily_CRAL-TRIO_dom,superfamily_Capsid/spike_ssD_virus,smart_CRAL-TRIO_dom,smart_Spectrin/alpha-actinin,smart_DH-domain,smart_Pleckstrin_homology,smart_SH3_domain,smart_Ig_sub,smart_Ig_sub2,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_CRAL-TRIO_dom,pfscan_Pleckstrin_homology,pfscan_SH3_domain,pfscan_Prot_kinase_dom,pfscan_Ig-like_dom,pfscan_DH-domain	-	no_errors	TRIO	HGNC	ENSG00000038382	tier1	-	-	27	0	0.00	16	5	23.81	76	0	0.00	66	38	36.54
ADAMTS12	0	genome.wustl.edu	37	5	33614360	33614360	+	Frame_Shift_Del	DEL	C	C	-			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	C	C	C	-	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	5	33614360	33614360	C	-	DEL	ADAMTS12	ENST00000504830	human	ensembl	74_37	-1	known	frame_shift_del	c.2510	p.S837fs	1.000	pfam_Thrombospondin_1_rpt,superfamily_Thrombospondin_1_rpt,smart_Thrombospondin_1_rpt,pfscan_Thrombospondin_1_rpt	pfam_ADAM_spacer1,pfam_Thrombospondin_1_rpt,pfam_Peptidase_M12B,pfam_Peptidase_M12B_N,superfamily_Thrombospondin_1_rpt,smart_Thrombospondin_1_rpt,pfscan_PLAC,pfscan_Thrombospondin_1_rpt,pfscan_Peptidase_M12B,prints_Peptidase_M12B_ADAM-TS	-	no_errors	ADAMTS12	HGNC	ENSG00000151388	tier1			62	0	0.00	40	4	9.09	60	0	0.00	71	9	11.25
FIGLA	0	genome.wustl.edu	37	2	71012615	71012634	+	Frame_Shift_Del	DEL	CACCACTGCCACCATCTGCC	CACCACTGCCACCATCTGCC	-			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	CACCACTGCCACCATCTGCC	CACCACTGCCACCATCTGCC	CACCACTGCCACCATCTGCC	-	CACCACTGCCACCATCTGCC	CACCACTGCCACCATCTGCC	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	2	71012615	71012634	CACCACTGCCACCATCTGCC	-	DEL	FIGLA	ENST00000332372	human	ensembl	74_37	-1	known	frame_shift_del	c.541_522	p.W174fs	0.953:0.953:0.995:0.997:0.997:0.998:0.999:1.000:1.000:0.998:0.961:0.960:0.964:0.956:0.996:0.999:1.000:1.000:1.000:1.000	NULL	pfam_bHLH_dom,superfamily_bHLH_dom,smart_bHLH_dom,pfscan_bHLH_dom	-	no_errors	FIGLA	HGNC	ENSG00000183733	tier1			58	0	0.00	19	7	26.92	58	0	0.00	19	7	26.92
ALK	0	genome.wustl.edu	37	2	30143133	30143133	+	Silent	SNP	G	G	A			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	2	30143133	30143133	G	A	SNP	ALK	ENST00000389048	human	ensembl	74_37	-1	known	silent	c.393	p.S131	0.851	NULL	pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_kinase_dom,pfam_MAM_dom,superfamily_Kinase-like_dom,superfamily_ConA-like_lec_gl_sf,superfamily_LDrepeatLR_classA_rpt,smart_LDrepeatLR_classA_rpt,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_MAM_dom,pfscan_Prot_kinase_dom,prints_Ser-Thr/Tyr_kinase_cat_dom	-	no_errors	ALK	HGNC	ENSG00000171094	tier1	-	-	29	0	0.00	13	13	50.00	14	0	0.00	8	11	57.89
CEACAM16	0	genome.wustl.edu	37	19	45208935	45208935	+	Missense_Mutation	SNP	C	C	T			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	19	45208935	45208935	C	T	SNP	CEACAM16	ENST00000405314	human	ensembl	74_37	+1	known	missense	c.737	p.T246M	0.026	smart_Ig_sub,smart_Ig_sub2,pfscan_Ig-like_dom	pfam_Ig_V-set,smart_Ig_sub,smart_Ig_sub2,pfscan_Ig-like_dom	-	no_errors	CEACAM16	HGNC	ENSG00000213892	tier1	-	-	93	0	0.00	10	14	58.33	65	0	0.00	5	34	87.18
GRI	0	genome.wustl.edu	37	8	145065511	145065511	+	Silent	SNP	C	C	A			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	8	145065511	145065511	C	A	SNP	GRI	ENST00000313269	human	ensembl	74_37	+1	known	silent	c.120	p.A40	0.238	NULL	pfam_Bax_inhibitor_1-related	-	no_errors	GRI	HGNC	ENSG00000178719	tier1	-	-	17	0	0.00	4	11	73.33	48	0	0.00	7	18	72.00
KRT14	0	genome.wustl.edu	37	17	39742691	39742691	+	Missense_Mutation	SNP	C	C	A			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	17	39742691	39742691	C	A	SNP	KRT14	ENST00000167586	human	ensembl	74_37	-1	known	missense	c.396	p.K132N	1.000	pfam_IF	pfam_IF,superfamily_Prefoldin,prints_Keratin_I	-	no_errors	KRT14	HGNC	ENSG00000186847	tier1	-	-	199	0	0.00	49	65	57.02	15	0	0.00	5	6	54.55
LOC440416	0	genome.wustl.edu	37	17	20805851	20805851	+	R	SNP	A	A	T			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	17	20805851	20805851	A	T	SNP	LOC440416	ENST00000577537	human	ensembl	74_37	+1	known	rna	NULL	NULL	1.000	-	-	-	no_errors	RP11-344E13.3	Clone_based_vega_gene	ENSG00000233098	tier1	-	-	139	0	0.00	31	36	53.73	61	0	0.00	7	54	88.52
MAGEB6	0	genome.wustl.edu	37	X	26211982	26211982	+	Missense_Mutation	SNP	A	A	G			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	X	26211982	26211982	A	G	SNP	MAGEB6	ENST00000379034	human	ensembl	74_37	+1	known	missense	c.19	p.S7G	0.006	pfam_Melanoma_ass_antigen_N	pfam_MAGE,pfam_Melanoma_ass_antigen_N,pfscan_MAGE	-	no_errors	MAGEB6	HGNC	ENSG00000176746	tier1	-	-	57	0	0.00	11	28	71.79	56	0	0.00	9	19	67.86
XYLB	0	genome.wustl.edu	37	3	38411731	38411732	+	R	INS	-	-	CACACACACACA			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	-	-	-	CACACACACACA	-	-	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	3	38411731	38411732	-	CACACACACACA	INS	XYLB	ENST00000487569	human	ensembl	74_37	+1	putative	rna	NULL	NULL	0.000:0.000	-	-	-	no_errors	XYLB	HGNC	ENSG00000093217	tier1			13	0	0.00	8	2	20.00	13	0	0.00	8	2	20.00
DPYSL5	0	genome.wustl.edu	37	2	27121590	27121590	+	Missense_Mutation	SNP	A	A	T			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	2	27121590	27121590	A	T	SNP	DPYSL5	ENST00000288699	human	ensembl	74_37	+1	known	missense	c.223	p.N75Y	1.000	pfam_Amidohydro_1,tigrfam_Hydantoinase/dihydroPyrase	pfam_Amidohydro_1,superfamily_Metal-dep_hydrolase_composite,tigrfam_Hydantoinase/dihydroPyrase	-	no_errors	DPYSL5	HGNC	ENSG00000157851	tier1	-	-	60	0	0.00	36	6	14.29	98	0	0.00	73	7	8.75
STARD9	0	genome.wustl.edu	37	15	42956067	42956067	+	Silent	SNP	A	A	G			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	15	42956067	42956067	A	G	SNP	STARD9	ENST00000290607	human	ensembl	74_37	+1	known	silent	c.1128	p.R376	1.000	pfam_Kinesin_motor_dom,superfamily_P-loop_NTPase,smart_Kinesin_motor_dom	pfam_Kinesin_motor_dom,pfam_START_lipid-bd_dom,pfam_FHA_dom,superfamily_P-loop_NTPase,superfamily_SMAD_FHA_domain,smart_Kinesin_motor_dom,smart_FHA_dom,pfscan_START_lipid-bd_dom,pfscan_Kinesin_motor_dom,prints_Kinesin_motor_dom	-	no_errors	STARD9	HGNC	ENSG00000159433	tier1	-	-	32	0	0.00	14	4	22.22	60	0	0.00	68	4	5.48
PRRC2B	0	genome.wustl.edu	37	9	134351084	134351084	+	Missense_Mutation	SNP	G	G	C			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	9	134351084	134351084	G	C	SNP	PRRC2B	ENST00000357304	human	ensembl	74_37	+1	known	missense	c.3568	p.G1190R	0.000	NULL	pfam_BAT2_N	-	no_errors	PRRC2B	HGNC	ENSG00000130723	tier1	-	-	47	0	0.00	40	4	8.89	45	0	0.00	47	4	7.84
COPS2	0	genome.wustl.edu	37	15	49431771	49431771	+	Missense_Mutation	SNP	T	T	G			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	T	T	T	G	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	15	49431771	49431771	T	G	SNP	COPS2	ENST00000299259	human	ensembl	74_37	-1	known	missense	c.326	p.E109A	1.000	NULL	pfam_PCI_dom,smart_PAM,smart_PCI_dom	-	no_errors	COPS2	HGNC	ENSG00000166200	tier1	-	-	53	0	0.00	22	4	15.38	69	0	0.00	47	4	7.84
AMICA1	0	genome.wustl.edu	37	11	118074177	118074215	+	In_Frame_Del	DEL	GGTTTTCTTGAACACCAGGTTCCCTAGGTGGATACTGCA	GGTTTTCTTGAACACCAGGTTCCCTAGGTGGATACTGCA	-			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	GGTTTTCTTGAACACCAGGTTCCCTAGGTGGATACTGCA	GGTTTTCTTGAACACCAGGTTCCCTAGGTGGATACTGCA	GGTTTTCTTGAACACCAGGTTCCCTAGGTGGATACTGCA	-	GGTTTTCTTGAACACCAGGTTCCCTAGGTGGATACTGCA	GGTTTTCTTGAACACCAGGTTCCCTAGGTGGATACTGCA	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	11	118074177	118074215	GGTTTTCTTGAACACCAGGTTCCCTAGGTGGATACTGCA	-	DEL	AMICA1	ENST00000356289	human	ensembl	74_37	-1	known	in_frame_del	c.738_700	p.CSIHLGNLVFKKT234in_frame_del	0.000:0.148:0.213:0.220:0.822:0.850:0.832:0.031:0.020:0.002:0.004:0.002:0.001:0.001:0.005:0.020:0.027:0.031:0.031:0.002:0.006:0.043:0.668:0.911:0.949:0.949:0.940:0.912:0.827:0.679:0.696:0.675:0.234:0.055:0.059:0.084:0.850:1.000:1.000	pfam_Ig_V-set,smart_Ig_sub,pfscan_Ig-like_dom	pfam_Ig_V-set,smart_Ig_sub,pfscan_Ig-like_dom	-	no_errors	AMICA1	HGNC	ENSG00000160593	tier1			76	0	0.00	82	7	7.87	76	0	0.00	82	7	7.87
ENSG00000226668	0	genome.wustl.edu	37	9	95646683	95646683	+	R	SNP	T	T	G			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	9	95646683	95646683	T	G	SNP	ENSG00000226668	ENST00000446878	human	ensembl	74_37	+1	putative	rna	NULL	NULL	0.008	-	-	-	no_errors	RP11-526D8.7	Clone_based_vega_gene	ENSG00000226668	tier1	-	-	144	0	0.00	75	24	24.24	8	0	0.00	2	1	33.33
PLXNB1	0	genome.wustl.edu	37	3	48461323	48461323	+	Missense_Mutation	SNP	G	G	A			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	3	48461323	48461323	G	A	SNP	PLXNB1	ENST00000296440	human	ensembl	74_37	-1	known	missense	c.2372	p.P791L	0.000	NULL	pfam_Plexin_cytoplasmic_RasGAP_dom,pfam_IPT,pfam_Semap_dom,pfam_Plexin_repeat,superfamily_Semap_dom,superfamily_Rho_GTPase_activation_prot,superfamily_Ig_E-set,superfamily_Plexin-like_fold,smart_Semap_dom,smart_Plexin-like_fold,smart_IPT,pfscan_Semap_dom	-	no_errors	PLXNB1	HGNC	ENSG00000164050	tier1	-	-	29	0	0.00	19	5	20.83	7	0	0.00	3	0	0.00
USP32P1	0	genome.wustl.edu	37	17	16706252	16706252	+	R	SNP	G	G	A			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	17	16706252	16706252	G	A	SNP	USP32P1	ENST00000341745	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.005	-	-	-	no_errors	USP32P1	HGNC	ENSG00000188933	tier1	rs200099225	-	57	0	0.00	32	5	13.51	24	0	0.00	8	0	0.00
GOLGA8DP	0	genome.wustl.edu	37	15	22709060	22709060	+	R	SNP	C	C	G			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	15	22709060	22709060	C	G	SNP	GOLGA8DP	ENST00000314246	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.005	-	-	-	no_errors	GOLGA8DP	HGNC	ENSG00000185182	tier1	-	-	16	0	0.00	14	10	41.67	0	0	0.00	0	0	0.00
KANK3	0	genome.wustl.edu	37	19	8388400	8388401	+	Frame_Shift_Ins	INS	-	-	GATT			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	19	8388400	8388401	-	GATT	INS	KANK3	ENST00000593649	human	ensembl	74_37	-1	known	frame_shift_ins	c.2405_2404	p.L802fs	0.049:0.050	NULL	pfam_Ankyrin_rpt,pfam_KN_motif,superfamily_Ankyrin_rpt-contain_dom,smart_Ankyrin_rpt,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,prints_Ankyrin_rpt	-	no_errors	KANK3	HGNC	ENSG00000186994	tier1			19	0	0.00	4	7	63.64	0	0	0.00	0	0	0.00
LOC100133091	0	genome.wustl.edu	37	7	76256104	76256105	+	R	INS	-	-	GGAGGGCGGTGT			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	7	76256104	76256105	-	GGAGGGCGGTGT	INS	LOC100133091	ENST00000418663	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.012:0.012	-	-	-	no_errors	AC004980.7	Clone_based_vega_gene	ENSG00000205485	tier1			3	0	0.00	3	0	0.00	3	0	0.00	3	0	0.00
SSC5D	0	genome.wustl.edu	37	19	56028663	56028663	+	Missense_Mutation	SNP	C	C	T			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	19	56028663	56028663	C	T	SNP	SSC5D	ENST00000389623	human	ensembl	74_37	+1	known	missense	c.3020	p.P1007L	0.001	NULL	pfam_SRCR,superfamily_Srcr_rcpt-rel,smart_Srcr_rcpt-rel,pfscan_SRCR,prints_SRCR	-	no_errors	SSC5D	HGNC	ENSG00000179954	tier1	-	-	21	0	0.00	23	12	34.29	3	0	0.00	5	5	50.00
FRMPD1	0	genome.wustl.edu	37	9	37731073	37731090	+	In_Frame_Del	DEL	CGTGGCCTTTGAATACCT	CGTGGCCTTTGAATACCT	-			TCGA-HS-A5N8-01A-11D-A26G-09	TCGA-HS-A5N8-10A-01D-A26G-09	CGTGGCCTTTGAATACCT	CGTGGCCTTTGAATACCT					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	acb9a894-a6b5-455d-9398-9b571e32f7f9	83917cee-8439-465e-a985-a291e4d88f3e	9	37731073	37731090	CGTGGCCTTTGAATACCT	-	DEL	FRMPD1	ENST00000377765	human	ensembl	74_37	+1	known	in_frame_del	c.831_848	p.VAFEYL278in_frame_del	0.017:0.990:0.998:0.994:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:0.985:1.000:1.000:0.998:1.000:1.000	pfam_FERM_central,superfamily_FERM_central,smart_Band_41_domain,pfscan_FERM_domain	pfam_FERM_central,pfam_PDZ,pfam_FERM_N,superfamily_FERM_central,superfamily_PDZ,smart_PDZ,smart_Band_41_domain,pfscan_FERM_domain,pfscan_PDZ	-	no_errors	FRMPD1	HGNC	ENSG00000070601	tier1			68	0	0.00	61	2	3.17	68	0	0.00	61	2	3.17