Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	default_gene_name	gene_name_source	 ensembl_gene_id	tier	dbSNP	GMAF	n_ref_count	n_alt_count	normal_vaf	t_ref_count	t_alt_count	tumor_vaf	n_ref_count_val	n_alt_count_val	normal_vaf_val	t_ref_count_val	t_alt_count_val	tumor_vaf_val
PIP5K1A	0	genome.wustl.edu	37	1	151206962	151206962	+	Missense_Mutation	SNP	G	G	A			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	1	151206962	151206962	G	A	SNP	PIP5K1A	ENST00000368888	human	ensembl	74_37	+1	known	missense	c.929	p.R310H	1.000	pfam_PInositol-4-P-5-kinase_core,smart_PInositol-4P-5-kinase_core_sub	pfam_PInositol-4-P-5-kinase_core,smart_PInositol-4P-5-kinase_core_sub	-	no_errors	PIP5K1A	HGNC	ENSG00000143398	tier1	-	-	75	0	0.00	77	28	26.67	66	0	0.00	136	44	24.31
ECM1	0	genome.wustl.edu	37	1	150483831	150483831	+	R	SNP	A	A	T			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	1	150483831	150483831	A	T	SNP	ECM1	ENST00000470432	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.001	-	-	-	no_errors	ECM1	HGNC	ENSG00000143369	tier1	-	-	31	0	0.00	26	11	29.73	46	0	0.00	89	35	28.23
CCT6P3	0	genome.wustl.edu	37	7	64531307	64531307	+	R	SNP	G	G	C			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	7	64531307	64531307	G	C	SNP	CCT6P3	ENST00000426828	human	ensembl	74_37	+1	known	rna	NULL	NULL	1.000	-	-	-	no_errors	CCT6P3	HGNC	ENSG00000234585	tier1	-	-	111	0	0.00	63	38	37.62	13	0	0.00	28	9	24.32
ENSG00000267749	0	genome.wustl.edu	37	19	2642868	2642868	+	R	SNP	C	C	A			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	19	2642868	2642868	C	A	SNP	ENSG00000267749	ENST00000587894	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.017	-	-	-	no_errors	CTC-265F19.1	Clone_based_vega_gene	ENSG00000267749	tier1	-	-	58	0	0.00	36	5	12.20	30	0	0.00	26	11	29.73
KIF20A	0	genome.wustl.edu	37	5	137520246	137520246	+	Missense_Mutation	SNP	T	T	A			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	5	137520246	137520246	T	A	SNP	KIF20A	ENST00000394894	human	ensembl	74_37	+1	known	missense	c.1564	p.S522T	1.000	NULL	pfam_Kinesin_motor_dom,superfamily_P-loop_NTPase,smart_Kinesin_motor_dom,pfscan_Kinesin_motor_dom,prints_Kinesin_motor_dom	-	no_errors	KIF20A	HGNC	ENSG00000112984	tier1	-	-	54	0	0.00	30	17	36.17	50	0	0.00	65	35	35.00
SMARCAL1	0	genome.wustl.edu	37	2	217279860	217279860	+	Nonsense_Mutation	SNP	C	C	T			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	2	217279860	217279860	C	T	SNP	SMARCAL1	ENST00000357276	human	ensembl	74_37	+1	known	nonsense	c.433	p.Q145*	0.003	NULL	pfam_HARP_dom,pfam_SNF2_N,pfam_Helicase_C,superfamily_P-loop_NTPase,smart_Helicase_ATP-bd,smart_Helicase_C,pfscan_Helicase_ATP-bd,pfscan_Helicase_C	-	no_errors	SMARCAL1	HGNC	ENSG00000138375	tier1	-	-	61	0	0.00	13	25	65.79	58	0	0.00	31	42	56.76
CSN2	0	genome.wustl.edu	37	4	70823302	70823302	+	Missense_Mutation	SNP	G	G	A			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	4	70823302	70823302	G	A	SNP	CSN2	ENST00000353151	human	ensembl	74_37	-1	known	missense	c.365	p.T122M	0.000	pirsf_Casein_beta	pfam_Casein,pirsf_Casein_beta	-	no_errors	CSN2	HGNC	ENSG00000135222	tier1	rs140189537	-	57	0	0.00	18	18	50.00	86	0	0.00	36	42	53.85
GABRB3	0	genome.wustl.edu	37	15	26793096	26793096	+	Silent	SNP	C	C	T			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	15	26793096	26793096	C	T	SNP	GABRB3	ENST00000299267	human	ensembl	74_37	-1	known	silent	c.1266	p.P422	0.973	pfam_Neurotrans-gated_channel_TM,superfamily_Neurotrans-gated_channel_TM,tigrfam_Neur_channel	pfam_Neurotrans-gated_channel_TM,pfam_Neur_chan_lig-bd,superfamily_Neur_chan_lig-bd,superfamily_Neurotrans-gated_channel_TM,prints_GABAA_rcpt,prints_GABAAb_rcpt,prints_Neur_channel,prints_GABBAg_rcpt,tigrfam_Neur_channel	-	no_errors	GABRB3	HGNC	ENSG00000166206	tier1	-	-	40	0	0.00	29	9	23.68	53	0	0.00	46	16	25.81
NUDT10	0	genome.wustl.edu	37	X	51076293	51076293	+	Missense_Mutation	SNP	C	C	T			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	X	51076293	51076293	C	T	SNP	NUDT10	ENST00000356450	human	ensembl	74_37	+1	known	missense	c.476	p.S159L	0.001	NULL	pfam_NUDIX_hydrolase_dom,superfamily_NUDIX_hydrolase_dom-like	-	no_errors	NUDT10	HGNC	ENSG00000122824	tier1	rs140448074	-	51	0	0.00	22	23	51.11	10	0	0.00	22	13	37.14
ITGB4	0	genome.wustl.edu	37	17	73748323	73748323	+	Missense_Mutation	SNP	C	C	T			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	17	73748323	73748323	C	T	SNP	ITGB4	ENST00000200181	human	ensembl	74_37	+1	known	missense	c.3862	p.L1288F	1.000	pirsf_Integrin_bsu-4,pfam_Fibronectin_type3,superfamily_Fibronectin_type3,smart_Fibronectin_type3,pfscan_Fibronectin_type3	pirsf_Integrin_bsu-4,pfam_Integrin_bsu_N,pfam_Fibronectin_type3,pfam_Calx_beta,pfam_Integrin_bsu_tail,pfam_EGF_extracell,superfamily_Fibronectin_type3,superfamily_Integrin_bsu_tail,superfamily_Plexin-like_fold,smart_Plexin-like_fold,smart_Integrin_bsu_N,smart_Calx_beta,smart_Fibronectin_type3,prints_Integrin_bsu,pfscan_Fibronectin_type3	-	no_errors	ITGB4	HGNC	ENSG00000132470	tier1	-	-	23	0	0.00	12	6	33.33	54	1	1.82	59	23	28.05
CDK12	0	genome.wustl.edu	37	17	37627390	37627390	+	Silent	SNP	A	A	G			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	17	37627390	37627390	A	G	SNP	CDK12	ENST00000447079	human	ensembl	74_37	+1	known	silent	c.1305	p.V435	0.931	NULL	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	-	no_errors	CDK12	HGNC	ENSG00000167258	tier1	-	-	32	0	0.00	28	6	17.65	111	0	0.00	133	38	22.22
LAMC1	0	genome.wustl.edu	37	1	183094669	183094669	+	Missense_Mutation	SNP	G	G	A			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	1	183094669	183094669	G	A	SNP	LAMC1	ENST00000258341	human	ensembl	74_37	+1	known	missense	c.2785	p.G929R	1.000	pfam_EGF_laminin,smart_EGF_laminin,pfscan_EGF_laminin	pfam_Laminin_N,pfam_EGF_laminin,pfam_Laminin_B_type_IV,smart_Laminin_N,smart_EGF_laminin,smart_EG-like_dom,smart_Laminin_B_subgr,pfscan_Laminin_B_type_IV,pfscan_EGF_laminin,pfscan_Laminin_N	-	no_errors	LAMC1	HGNC	ENSG00000135862	tier1	-	-	106	0	0.00	172	20	10.42	74	1	1.33	191	22	10.33
C11orf44	0	genome.wustl.edu	37	11	130542983	130542983	+	Missense_Mutation	SNP	C	C	T			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	11	130542983	130542983	C	T	SNP	C11orf44	ENST00000317019	human	ensembl	74_37	+1	putative	missense	c.110	p.S37F	0.001	NULL	NULL	-	no_errors	C11orf44	HGNC	ENSG00000175728	tier1	-	-	37	0	0.00	18	17	48.57	18	0	0.00	11	21	65.62
OR6K6	0	genome.wustl.edu	37	1	158725397	158725397	+	Silent	SNP	C	C	A			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	1	158725397	158725397	C	A	SNP	OR6K6	ENST00000368144	human	ensembl	74_37	+1	known	silent	c.792	p.A264	0.308	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR6K6	HGNC	ENSG00000180433	tier1	-	-	113	0	0.00	119	44	26.99	49	0	0.00	105	50	32.26
NBPF22P	0	genome.wustl.edu	37	5	85592265	85592265	+	R	SNP	G	G	A			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	5	85592265	85592265	G	A	SNP	NBPF22P	ENST00000590707	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	NBPF22P	HGNC	ENSG00000205449	tier1	-	-	112	0	0.00	65	48	42.11	32	0	0.00	40	18	31.03
ZNF454	0	genome.wustl.edu	37	5	178373906	178373906	+	Missense_Mutation	SNP	G	G	A			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	5	178373906	178373906	G	A	SNP	ZNF454	ENST00000320129	human	ensembl	74_37	+1	known	missense	c.169	p.G57R	1.000	superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,pfscan_Krueppel-associated_box	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF454	HGNC	ENSG00000178187	tier1	-	-	50	0	0.00	34	22	39.29	71	0	0.00	92	50	34.72
MAMDC4	0	genome.wustl.edu	37	9	139750925	139750925	+	Missense_Mutation	SNP	G	G	T			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	9	139750925	139750925	G	T	SNP	MAMDC4	ENST00000445819	human	ensembl	74_37	+1	known	missense	c.1855	p.V619F	0.000	pfam_MAM_dom,superfamily_ConA-like_lec_gl_sf,smart_MAM_dom,pfscan_MAM_dom	pfam_MAM_dom,pfam_LDrepeatLR_classA_rpt,superfamily_ConA-like_lec_gl_sf,superfamily_LDrepeatLR_classA_rpt,smart_LDrepeatLR_classA_rpt,smart_MAM_dom,pfscan_LDrepeatLR_classA_rpt,pfscan_MAM_dom,prints_LDrepeatLR_classA_rpt	-	no_errors	MAMDC4	HGNC	ENSG00000177943	tier1	rs191106356	GMAF=0.0005	70	0	0.00	35	17	32.69	46	0	0.00	61	16	20.78
RAD18	0	genome.wustl.edu	37	3	8981242	8981242	+	Missense_Mutation	SNP	T	T	C			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	3	8981242	8981242	T	C	SNP	RAD18	ENST00000264926	human	ensembl	74_37	-1	known	missense	c.700	p.R234G	0.932	NULL	pfam_SAP_dom,pfam_Znf_C3HC4_RING-type,smart_Znf_RING,smart_Znf_Rad18_put,smart_SAP_dom,pfscan_Znf_RING,pfscan_SAP_dom	-	no_errors	RAD18	HGNC	ENSG00000070950	tier1	-	-	88	0	0.00	63	29	31.52	63	0	0.00	85	46	34.85
PLCE1	0	genome.wustl.edu	37	10	96058263	96058263	+	Silent	SNP	C	C	A			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	10	96058263	96058263	C	A	SNP	PLCE1	ENST00000260766	human	ensembl	74_37	+1	known	silent	c.5295	p.A1765	1.000	pfam_PLipase_C_Pinositol-sp_Y,superfamily_PLC-like_Pdiesterase_TIM-brl,smart_PLipase_C_Pinositol-sp_Y,pfscan_PLipase_C_Pinositol-sp_Y	pfam_PLipase_C_PInositol-sp_X_dom,pfam_PLipase_C_Pinositol-sp_Y,pfam_Ras-assoc,pfam_RasGRF_CDC25,pfam_PLipase_C_EF-hand-like,pfam_C2_dom,superfamily_PLC-like_Pdiesterase_TIM-brl,superfamily_Ras_GEF_dom,superfamily_C2_dom,smart_RasGRF_CDC25,smart_PLipase_C_PInositol-sp_X_dom,smart_PLipase_C_Pinositol-sp_Y,smart_C2_dom,smart_Ras-assoc,pfscan_C2_dom,pfscan_Ras-assoc,pfscan_PLipase_C_PInositol-sp_X_dom,pfscan_PLipase_C_Pinositol-sp_Y,pfscan_RasGRF_CDC25,prints_Pinositol_PLipase_C	-	no_errors	PLCE1	HGNC	ENSG00000138193	tier1	-	-	49	0	0.00	26	14	35.00	40	0	0.00	49	14	22.22
LRRC59	0	genome.wustl.edu	37	17	48460388	48460388	+	Missense_Mutation	SNP	C	C	G			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	17	48460388	48460388	C	G	SNP	LRRC59	ENST00000225972	human	ensembl	74_37	-1	known	missense	c.885	p.E295D	0.997	NULL	pfam_Leu-rich_rpt,smart_Leu-rich_rpt_typical-subtyp	-	no_errors	LRRC59	HGNC	ENSG00000108829	tier1	-	-	53	0	0.00	37	17	31.48	24	0	0.00	50	19	27.54
WWC1	0	genome.wustl.edu	37	5	167894930	167894930	+	Missense_Mutation	SNP	G	G	A			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	5	167894930	167894930	G	A	SNP	WWC1	ENST00000265293	human	ensembl	74_37	+1	known	missense	c.3236	p.G1079D	1.000	NULL	pfam_WW_dom,superfamily_C2_dom,superfamily_WW_dom,smart_WW_dom,pfscan_WW_dom	-	no_errors	WWC1	HGNC	ENSG00000113645	tier1	-	-	35	0	0.00	12	7	35.00	37	0	0.00	43	27	38.57
ERAP1	0	genome.wustl.edu	37	5	96098915	96098915	+	Missense_Mutation	SNP	C	C	T			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	5	96098915	96098915	C	T	SNP	ERAP1	ENST00000296754	human	ensembl	74_37	-1	known	missense	c.2836	p.A946T	0.000	NULL	pfam_Peptidase_M1_N,prints_Peptidase_M1_N	-	no_errors	ERAP1	HGNC	ENSG00000164307	tier1	-	-	46	0	0.00	41	33	44.59	37	0	0.00	31	29	48.33
ATR	0	genome.wustl.edu	37	3	142185195	142185195	+	Missense_Mutation	SNP	A	A	G			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	3	142185195	142185195	A	G	SNP	ATR	ENST00000350721	human	ensembl	74_37	-1	known	missense	c.6868	p.W2290R	1.000	superfamily_Kinase-like_dom	pfam_PI3/4_kinase_cat_dom,pfam_PIK-rel_kinase_FAT,pfam_UME,pfam_FATC,superfamily_Kinase-like_dom,superfamily_ARM-type_fold,smart_UME,smart_PI3/4_kinase_cat_dom,pfscan_PIK_FAT,pfscan_FATC,pfscan_HEAT_type_2,pfscan_PI3/4_kinase_cat_dom	-	no_errors	ATR	HGNC	ENSG00000175054	tier1	-	-	39	0	0.00	36	20	35.71	72	0	0.00	95	58	37.66
DDX19B	0	genome.wustl.edu	37	16	70363935	70363935	+	Silent	SNP	G	G	T			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	16	70363935	70363935	G	T	SNP	DDX19B	ENST00000288071	human	ensembl	74_37	+1	known	silent	c.987	p.G329	1.000	superfamily_P-loop_NTPase,pfscan_Helicase_C	pfam_D/R_helicase_DEAD/DEAH_N,pfam_Helicase_C,superfamily_P-loop_NTPase,smart_Helicase_ATP-bd,smart_Helicase_C,pfscan_Helicase_ATP-bd,pfscan_Helicase_C,pfscan_R_helicase_DEAD_Q_motif	-	no_errors	DDX19B	HGNC	ENSG00000157349	tier1	-	-	103	0	0.00	66	28	29.79	45	0	0.00	55	28	33.73
BICD1	0	genome.wustl.edu	37	12	32369245	32369245	+	Missense_Mutation	SNP	C	C	T			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	12	32369245	32369245	C	T	SNP	BICD1	ENST00000281474	human	ensembl	74_37	+1	known	missense	c.278	p.T93M	1.000	pfam_Bicaudal-D_microtubule-assoc	pfam_Bicaudal-D_microtubule-assoc,superfamily_SPOC_like_C_dom	-	no_errors	BICD1	HGNC	ENSG00000151746	tier1	-	-	74	0	0.00	39	19	32.20	54	0	0.00	55	14	20.29
SAP130	0	genome.wustl.edu	37	2	128700080	128700080	+	Missense_Mutation	SNP	A	A	C			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	A	A	A	C	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	2	128700080	128700080	A	C	SNP	SAP130	ENST00000357702	human	ensembl	74_37	-1	known	missense	c.3011	p.L1004R	1.000	NULL	NULL	-	no_errors	SAP130	HGNC	ENSG00000136715	tier1	-	-	94	0	0.00	61	29	32.22	49	0	0.00	63	23	26.74
RPTN	0	genome.wustl.edu	37	1	152128339	152128339	+	Missense_Mutation	SNP	A	A	T			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	1	152128339	152128339	A	T	SNP	RPTN	ENST00000316073	human	ensembl	74_37	-1	known	missense	c.1236	p.S412R	0.000	NULL	pfam_S100_Ca-bd_sub,pfscan_EF_hand_dom	-	no_errors	RPTN	HGNC	ENSG00000215853	tier1	-	-	387	0	0.00	370	146	28.24	40	0	0.00	111	32	22.22
YWHAB	0	genome.wustl.edu	37	20	43532648	43532648	+	Silent	SNP	A	A	G			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	20	43532648	43532648	A	G	SNP	YWHAB	ENST00000353703	human	ensembl	74_37	+1	known	silent	c.315	p.K105	1.000	pfam_14-3-3_domain,superfamily_14-3-3_domain,smart_14-3-3_domain,pirsf_14-3-3,prints_14-3-3	pfam_14-3-3_domain,superfamily_14-3-3_domain,smart_14-3-3_domain,pirsf_14-3-3,prints_14-3-3	-	no_errors	YWHAB	HGNC	ENSG00000166913	tier1	-	-	65	0	0.00	41	35	46.05	65	0	0.00	96	32	25.00
LOC101929290	0	genome.wustl.edu	37	8	11177509	11177509	+	R	SNP	C	C	A			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	8	11177509	11177509	C	A	SNP	LOC101929290	ENST00000498997	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	AF131216.6	Clone_based_vega_gene	ENSG00000246477	tier1	-	-	22	0	0.00	11	6	35.29	28	0	0.00	35	20	36.36
POTEF	0	genome.wustl.edu	37	2	130832919	130832919	+	Missense_Mutation	SNP	A	A	G			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	2	130832919	130832919	A	G	SNP	POTEF	ENST00000357462	human	ensembl	74_37	-1	known	missense	c.2126	p.V709A	1.000	pfam_Actin-related,smart_Actin-related	pfam_Actin-related,pfam_Ankyrin_rpt,superfamily_Ankyrin_rpt-contain_dom,smart_Ankyrin_rpt,smart_Actin-related,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,prints_Actin-related	-	no_errors	POTEF	HGNC	ENSG00000196604	tier1	-	-	182	0	0.00	117	57	32.76	33	0	0.00	33	11	25.00
FCRL1	0	genome.wustl.edu	37	1	157772364	157772364	+	Missense_Mutation	SNP	G	G	C			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	1	157772364	157772364	G	C	SNP	FCRL1	ENST00000368176	human	ensembl	74_37	-1	known	missense	c.410	p.A137G	0.002	pfam_Ig_I-set,smart_Ig_sub,smart_Ig_sub2,pfscan_Ig-like_dom	pfam_Ig_I-set,smart_Ig_sub,smart_Ig_sub2,pfscan_Ig-like_dom	-	no_errors	FCRL1	HGNC	ENSG00000163534	tier1	-	-	43	0	0.00	56	15	21.13	48	0	0.00	121	38	23.90
SYNJ2	0	genome.wustl.edu	37	6	158490642	158490642	+	Missense_Mutation	SNP	C	C	T			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	6	158490642	158490642	C	T	SNP	SYNJ2	ENST00000355585	human	ensembl	74_37	+1	known	missense	c.1877	p.S626L	0.994	pfam_Endo/exonuclease/phosphatase,superfamily_Endo/exonuclease/phosphatase,smart_IPPc	pfam_Syja_N,pfam_DUF1866,pfam_Endo/exonuclease/phosphatase,superfamily_Endo/exonuclease/phosphatase,smart_IPPc,pfscan_RRM_dom,pfscan_Syja_N	-	no_errors	SYNJ2	HGNC	ENSG00000078269	tier1	-	-	106	0	0.00	81	39	32.50	31	0	0.00	48	31	39.24
SP4	0	genome.wustl.edu	37	7	21469742	21469742	+	Missense_Mutation	SNP	C	C	T			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	7	21469742	21469742	C	T	SNP	SP4	ENST00000222584	human	ensembl	74_37	+1	known	missense	c.959	p.S320F	1.000	NULL	pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2	-	no_errors	SP4	HGNC	ENSG00000105866	tier1	-	-	97	0	0.00	25	36	59.02	50	0	0.00	34	39	53.42
PTPN22	0	genome.wustl.edu	37	1	114372223	114372223	+	Silent	SNP	T	T	A			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	1	114372223	114372223	T	A	SNP	PTPN22	ENST00000359785	human	ensembl	74_37	-1	known	silent	c.2241	p.T747	1.000	pirsf_Non-rcpt_Tyr_Pase_8/22	pfam_Tyr_Pase_rcpt/non-rcpt,smart_Tyr_Pase_rcpt/non-rcpt,smart_Tyr_Pase_cat,pirsf_Non-rcpt_Tyr_Pase_8/22,pfscan_Tyr/Dual-sp_Pase,pfscan_Tyr_Pase_rcpt/non-rcpt,prints_Tyr_Pase_rcpt/non-rcpt	-	no_errors	PTPN22	HGNC	ENSG00000134242	tier1	-	-	74	0	0.00	20	21	51.22	41	0	0.00	27	32	54.24
NEB	0	genome.wustl.edu	37	2	152426886	152426886	+	Silent	SNP	A	A	G			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	2	152426886	152426886	A	G	SNP	NEB	ENST00000397345	human	ensembl	74_37	-1	known	silent	c.17139	p.H5713	0.065	pfam_Nebulin_35r-motif,smart_Nebulin_35r-motif,pfscan_Nebulin_35r-motif	pfam_Nebulin_35r-motif,pfam_SH3_domain,pfam_SH3_2,superfamily_SH3_domain,superfamily_Adhesion_dom,superfamily_6-PGluconate_DH_C-like,smart_Nebulin_35r-motif,smart_SH3_domain,pfscan_Nebulin_35r-motif,pfscan_SH3_domain,prints_Nebulin	-	no_errors	NEB	HGNC	ENSG00000183091	tier1	-	-	68	0	0.00	44	25	36.23	38	0	0.00	50	31	38.27
RSPH1	0	genome.wustl.edu	37	21	43905819	43905819	+	Missense_Mutation	SNP	T	T	C			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	21	43905819	43905819	T	C	SNP	RSPH1	ENST00000291536	human	ensembl	74_37	-1	known	missense	c.461	p.H154R	1.000	smart_MORN	pfam_MORN,smart_MORN	-	no_errors	RSPH1	HGNC	ENSG00000160188	tier1	-	-	47	0	0.00	21	20	48.78	82	0	0.00	30	38	55.88
IGF2BP1	0	genome.wustl.edu	37	17	47117380	47117380	+	Missense_Mutation	SNP	A	A	T			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	17	47117380	47117380	A	T	SNP	IGF2BP1	ENST00000290341	human	ensembl	74_37	+1	known	missense	c.745	p.T249S	0.998	pfam_KH_dom_type_1,smart_KH_dom,pfscan_KH_dom_type_1	pfam_KH_dom_type_1,pfam_RRM_dom,smart_RRM_dom,smart_KH_dom,pfscan_KH_dom_type_1,pfscan_RRM_dom	-	no_errors	IGF2BP1	HGNC	ENSG00000159217	tier1	-	-	34	0	0.00	24	11	31.43	39	0	0.00	18	18	50.00
ALMS1	0	genome.wustl.edu	37	2	73676394	73676394	+	Missense_Mutation	SNP	C	C	T			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	2	73676394	73676394	C	T	SNP	ALMS1	ENST00000264448	human	ensembl	74_37	+1	known	missense	c.2737	p.P913S	0.002	NULL	NULL	-	no_errors	ALMS1	HGNC	ENSG00000116127	tier1	-	-	28	0	0.00	41	10	19.61	73	0	0.00	107	35	24.65
CARNS1	0	genome.wustl.edu	37	11	67191267	67191267	+	Missense_Mutation	SNP	T	T	C			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	11	67191267	67191267	T	C	SNP	CARNS1	ENST00000445895	human	ensembl	74_37	+1	known	missense	c.2048	p.V683A	1.000	pfscan_ATP-grasp	superfamily_PreATP-grasp_dom,superfamily_TIL_dom,pfscan_ATP-grasp	-	no_errors	CARNS1	HGNC	ENSG00000172508	tier1	-	-	30	0	0.00	8	13	61.90	24	0	0.00	21	8	27.59
FAM21A	0	genome.wustl.edu	37	10	51829380	51829380	+	Missense_Mutation	SNP	G	G	A			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	10	51829380	51829380	G	A	SNP	FAM21A	ENST00000282633	human	ensembl	74_37	+1	known	missense	c.200	p.G67E	1.000	NULL	NULL	-	no_errors	FAM21A	HGNC	ENSG00000099290	tier1	-	-	113	0	0.00	68	21	23.60	67	0	0.00	92	28	23.33
ZNF141	0	genome.wustl.edu	37	4	376791	376791	+	R	SNP	C	C	A			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	4	376791	376791	C	A	SNP	ZNF141	ENST00000579770	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.089	-	-	-	no_errors	ZNF141	HGNC	ENSG00000131127	tier1	-	-	17	0	0.00	18	8	30.77	25	0	0.00	19	20	50.00
NFASC	0	genome.wustl.edu	37	1	204985815	204985815	+	R	SNP	G	G	A			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	1	204985815	204985815	G	A	SNP	NFASC	ENST00000495396	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.031	-	-	-	no_errors	NFASC	HGNC	ENSG00000163531	tier1	-	-	48	0	0.00	42	19	31.15	49	0	0.00	115	25	17.86
PAPPA2	0	genome.wustl.edu	37	1	176668407	176668407	+	Missense_Mutation	SNP	T	T	C			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	1	176668407	176668407	T	C	SNP	PAPPA2	ENST00000367662	human	ensembl	74_37	+1	known	missense	c.2918	p.F973S	1.000	superfamily_Fibronectin_type3	pfam_Notch_dom,pfam_Sushi_SCR_CCP,pfam_Peptidase_M43,superfamily_ConA-like_lec_gl_sf,superfamily_Sushi_SCR_CCP,superfamily_Fibronectin_type3,superfamily_Notch_dom,smart_LamG-like,smart_Notch_dom,smart_Sushi_SCR_CCP,pfscan_Sushi_SCR_CCP,tigrfam_Myxo_disulph_rpt	-	no_errors	PAPPA2	HGNC	ENSG00000116183	tier1	-	-	36	0	0.00	64	21	24.71	34	0	0.00	70	22	23.91
ATXN3L	0	genome.wustl.edu	37	X	13337121	13337121	+	Silent	SNP	G	G	A			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	X	13337121	13337121	G	A	SNP	ATXN3L	ENST00000380622	human	ensembl	74_37	-1	known	silent	c.933	p.H311	0.001	prints_Josephin	pfam_Josephin,pfam_Ubiquitin-int_motif,smart_Ubiquitin-int_motif,prints_Josephin,pfscan_Josephin,pfscan_Ubiquitin-int_motif	-	no_errors	ATXN3L	HGNC	ENSG00000123594	tier1	-	-	148	0	0.00	90	28	23.73	69	0	0.00	83	45	35.16
LSR	0	genome.wustl.edu	37	19	35758744	35758744	+	Silent	SNP	G	G	A			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	19	35758744	35758744	G	A	SNP	LSR	ENST00000361790	human	ensembl	74_37	+1	known	silent	c.1932	p.R644	0.991	NULL	pfam_LISCH7,smart_Ig_sub,pfscan_Ig-like_dom	-	no_errors	LSR	HGNC	ENSG00000105699	tier1	-	-	103	0	0.00	53	13	19.70	18	0	0.00	45	7	13.46
PPIL6	0	genome.wustl.edu	37	6	109748056	109748056	+	Missense_Mutation	SNP	C	C	G			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	6	109748056	109748056	C	G	SNP	PPIL6	ENST00000521072	human	ensembl	74_37	-1	known	missense	c.625	p.G209R	1.000	pfam_Cyclophilin-like_PPIase_dom,superfamily_Cyclophilin-like_PPIase_dom,pfscan_Cyclophilin-like_PPIase_dom,prints_Cyclophilin-like_PPIase_dom	pfam_Cyclophilin-like_PPIase_dom,superfamily_Cyclophilin-like_PPIase_dom,pfscan_Cyclophilin-like_PPIase_dom,prints_Cyclophilin-like_PPIase_dom	-	no_errors	PPIL6	HGNC	ENSG00000185250	tier1	-	-	43	0	0.00	32	16	33.33	62	0	0.00	76	42	35.29
HYDIN	0	genome.wustl.edu	37	16	71113818	71113818	+	Missense_Mutation	SNP	G	G	T			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	16	71113818	71113818	G	T	SNP	HYDIN	ENST00000448089	human	ensembl	74_37	-1	known	missense	c.1708	p.P570T	1.000	NULL	superfamily_PapD-like	-	no_errors	HYDIN	HGNC	ENSG00000157423	tier1	-	-	28	0	0.00	9	7	43.75	52	0	0.00	60	40	40.00
XYLT2	0	genome.wustl.edu	37	17	48434025	48434025	+	Missense_Mutation	SNP	G	G	A			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	17	48434025	48434025	G	A	SNP	XYLT2	ENST00000017003	human	ensembl	74_37	+1	known	missense	c.1636	p.G546S	1.000	pfam_XylT	pfam_XylT,pfam_Glyco_trans_14	-	no_errors	XYLT2	HGNC	ENSG00000015532	tier1	-	-	27	0	0.00	16	7	30.43	17	0	0.00	11	14	56.00
DUSP27	0	genome.wustl.edu	37	1	167097466	167097466	+	Missense_Mutation	SNP	G	G	A			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	1	167097466	167097466	G	A	SNP	DUSP27	ENST00000271385	human	ensembl	74_37	+1	known	missense	c.3098	p.R1033Q	0.989	NULL	pfam_Dual-sp_phosphatase_cat-dom,smart_Dual-sp_phosphatase_subgr_cat,pfscan_Tyr/Dual-sp_Pase,pfscan_Dual-sp_phosphatase_subgr_cat,prints_Atypical_DUSP,prints_Atypical_DUSP_famA	-	no_errors	DUSP27	HGNC	ENSG00000198842	tier1	-	-	30	0	0.00	30	8	21.05	56	1	1.75	143	36	20.11
DST	0	genome.wustl.edu	37	6	56472778	56472778	+	Silent	SNP	C	C	T			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	6	56472778	56472778	C	T	SNP	DST	ENST00000370754	human	ensembl	74_37	-1	known	silent	c.6549	p.G2183	0.237	superfamily_ABC1_TM_dom	pfam_Spectrin_repeat,pfam_Plectin_repeat,pfam_CH-domain,pfam_GAS2_dom,pfam_CAMSAP_CH,superfamily_CH-domain,superfamily_GAS2_dom,superfamily_ABC1_TM_dom,smart_CH-domain,smart_Spectrin/alpha-actinin,smart_Plectin_repeat,smart_EF_hand_dom,smart_GAS2_dom,pfscan_CH-domain,pfscan_EF_hand_dom	-	no_errors	DST	HGNC	ENSG00000151914	tier1	-	-	47	0	0.00	14	19	57.58	51	0	0.00	21	36	63.16
TTN	0	genome.wustl.edu	37	2	179469727	179469727	+	Missense_Mutation	SNP	G	G	T			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	2	179469727	179469727	G	T	SNP	TTN	ENST00000342992	human	ensembl	74_37	-1	known	missense	c.46473	p.H15491Q	0.044	pfam_Ig_I-set,superfamily_Calpain_domain_III,superfamily_Fibronectin_type3,superfamily_RNaseH-like_dom,smart_Ig_sub,pfscan_Ig-like_dom	pfam_Ig_I-set,pfam_Fibronectin_type3,pfam_Immunoglobulin,pfam_Ig_V-set,pfam_Titin_Z,pfam_PPAK_motif,pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,superfamily_Fibronectin_type3,superfamily_Calpain_domain_III,superfamily_RNaseH-like_dom,smart_Ig_sub,smart_Ig_sub2,smart_Ig_V-set_subgr,smart_Fibronectin_type3,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Fibronectin_type3,pfscan_Prot_kinase_dom,pfscan_Ig-like_dom	-	no_errors	TTN	HGNC	ENSG00000155657	tier1	-	-	54	0	0.00	32	12	27.27	66	0	0.00	115	64	35.75
ATM	0	genome.wustl.edu	37	11	108199905	108199905	+	Missense_Mutation	SNP	T	T	C			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	11	108199905	108199905	T	C	SNP	ATM	ENST00000278616	human	ensembl	74_37	+1	known	missense	c.7247	p.L2416P	1.000	pfam_PIK-rel_kinase_FAT,superfamily_ARM-type_fold,pfscan_PIK_FAT	pfam_PIK-rel_kinase_FAT,pfam_PI3/4_kinase_cat_dom,pfam_TAN,pfam_FATC,superfamily_Kinase-like_dom,superfamily_ARM-type_fold,smart_PI3/4_kinase_cat_dom,pfscan_PIK_FAT,pfscan_FATC,pfscan_PI3/4_kinase_cat_dom	-	no_errors	ATM	HGNC	ENSG00000149311	tier1	-	-	36	0	0.00	17	23	57.50	58	0	0.00	40	44	52.38
AMACR	0	genome.wustl.edu	37	5	34005864	34005864	+	Missense_Mutation	SNP	A	A	G			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	5	34005864	34005864	A	G	SNP	AMACR	ENST00000335606	human	ensembl	74_37	-1	known	missense	c.388	p.S130P	1.000	pfam_CoA-Trfase_fam_III,superfamily_CoA-Trfase_III_dom	pfam_CoA-Trfase_fam_III,superfamily_CoA-Trfase_III_dom	-	no_errors	AMACR	HGNC	ENSG00000242110	tier1	-	-	17	0	0.00	23	5	17.24	51	0	0.00	67	36	34.62
PDE3A	0	genome.wustl.edu	37	12	20799442	20799444	+	In_Frame_Del	DEL	CCA	CCA	-			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	CCA	CCA	CCA	-	CCA	CCA	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	12	20799442	20799444	CCA	-	DEL	PDE3A	ENST00000359062	human	ensembl	74_37	+1	known	in_frame_del	c.2270_2272	p.T758in_frame_del	1.000:1.000:1.000	smart_HD/PDEase_dom	pfam_PDEase_catalytic_dom,smart_HD/PDEase_dom	-	no_errors	PDE3A	HGNC	ENSG00000172572	tier1			48	0	0.00	33	11	25.00	60	0	0.00	69	33	32.35
LOC440905	0	genome.wustl.edu	37	2	130792230	130792230	+	R	DEL	A	A	-			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	A	A	A	-	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	2	130792230	130792230	A	-	DEL	LOC440905	ENST00000444030	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	AC018865.8	Clone_based_vega_gene	ENSG00000180178	tier1			23	0	0.00	17	7	29.17	53	0	0.00	67	45	40.18
PCDH9	0	genome.wustl.edu	37	13	67800272	67800282	+	Frame_Shift_Del	DEL	AAGCGTGTGCA	AAGCGTGTGCA	-			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	AAGCGTGTGCA	AAGCGTGTGCA	AAGCGTGTGCA	-	AAGCGTGTGCA	AAGCGTGTGCA	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	13	67800272	67800282	AAGCGTGTGCA	-	DEL	PCDH9	ENST00000377865	human	ensembl	74_37	-1	known	frame_shift_del	c.2301_2291	p.L764fs	0.015:0.996:0.997:0.267:0.988:1.000:1.000:1.000:1.000:1.000:1.000	superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin	pfam_Cadherin,pfam_Protocadherin,pfam_Cadherin_N,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin,prints_Cadherin	-	no_errors	PCDH9	HGNC	ENSG00000184226	tier1			56	0	0.00	24	7	22.58	56	0	0.00	24	7	22.58
DCAF17	0	genome.wustl.edu	37	2	172325408	172325409	+	Frame_Shift_Ins	INS	-	-	T			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	-	-	-	T	-	-	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	2	172325408	172325409	-	T	INS	DCAF17	ENST00000375255	human	ensembl	74_37	+1	known	frame_shift_ins	c.849_850	p.L283fs	0.959:0.976	NULL	NULL	-	no_errors	DCAF17	HGNC	ENSG00000115827	tier1			63	0	0.00	42	12	22.22	57	0	0.00	73	9	10.98
SLC6A7	0	genome.wustl.edu	37	5	149583220	149583236	+	Frame_Shift_Del	DEL	CCTGGCCCAGGCCCTGG	CCTGGCCCAGGCCCTGG	-			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	CCTGGCCCAGGCCCTGG	CCTGGCCCAGGCCCTGG	CCTGGCCCAGGCCCTGG	-	CCTGGCCCAGGCCCTGG	CCTGGCCCAGGCCCTGG	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	5	149583220	149583236	CCTGGCCCAGGCCCTGG	-	DEL	SLC6A7	ENST00000230671	human	ensembl	74_37	+1	known	frame_shift_del	c.1098_1094	p.A366fs	0.234:0.112:0.122:0.447:0.481:0.986:0.995:0.993:1.000:1.000:1.000:1.000:1.000:1.000:0.155:1.000:1.000	pfam_Na/ntran_symport,pfscan_Na/ntran_symport	pfam_Na/ntran_symport,pfscan_Na/ntran_symport,prints_Na/ntran_symport	-	no_errors	SLC6A7	HGNC	ENSG00000011083	tier1			20	0	0.00	26	3	10.34	20	0	0.00	26	3	10.34
VWF	0	genome.wustl.edu	37	12	6143854	6143858	+	Frame_Shift_Del	DEL	CTGCA	CTGCA	-			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	CTGCA	CTGCA	CTGCA	-	CTGCA	CTGCA	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	12	6143854	6143858	CTGCA	-	DEL	VWF	ENST00000261405	human	ensembl	74_37	-1	known	frame_shift_del	c.2685_2681	p.V894fs	1.000:1.000:1.000:0.796:0.801	pirsf_VWF,pfam_VWF_type-D,smart_VWC_out,smart_VWF_type-D	pirsf_VWF,pfam_VWF_type-D,pfam_VWF_A,pfam_Unchr_dom_Cys-rich,pfam_TIL_dom,pfam_VWF_C,superfamily_TIL_dom,smart_VWF_type-D,smart_Unchr_dom_Cys-rich,smart_VWC_out,smart_VWF_C,smart_VWF_A,smart_Cys_knot_C,pfscan_Cys_knot_C,pfscan_VWF_A,pfscan_VWF_C	-	no_errors	VWF	HGNC	ENSG00000110799	tier1			111	0	0.00	108	17	13.60	111	0	0.00	108	17	13.60
VWF	0	genome.wustl.edu	37	12	6143852	6143852	+	Splice_Site	DEL	A	A	-			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	A	A	A	-	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	12	6143852	6143852	A	-	DEL	VWF	ENST00000261405	human	ensembl	74_37	-1	known	splice_site_del	c.2685+2	e19+2	1.000	-	-	-	no_errors	VWF	HGNC	ENSG00000110799	tier1			104	0	0.00	77	20	20.62	110	0	0.00	107	17	13.71
CATSPERD	0	genome.wustl.edu	37	19	5745969	5745979	+	Frame_Shift_Del	DEL	CTGTCTTTTGA	CTGTCTTTTGA	-			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	CTGTCTTTTGA	CTGTCTTTTGA	CTGTCTTTTGA	-	CTGTCTTTTGA	CTGTCTTTTGA	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	19	5745969	5745979	CTGTCTTTTGA	-	DEL	CATSPERD	ENST00000381624	human	ensembl	74_37	+1	known	frame_shift_del	c.703_713	p.S236fs	0.018:0.019:0.007:0.005:0.038:0.040:0.055:0.053:0.027:0.013:0.011	superfamily_WD40_repeat_dom	superfamily_WD40_repeat_dom	-	no_errors	CATSPERD	HGNC	ENSG00000174898	tier1			57	0	0.00	59	11	15.71	57	0	0.00	59	11	15.71
COL6A3	0	genome.wustl.edu	37	2	238232753	238232754	+	R	INS	-	-	C			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	-	-	-	C	-	-	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	2	238232753	238232754	-	C	INS	COL6A3	ENST00000473258	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.025:0.031	-	-	-	no_errors	COL6A3	HGNC	ENSG00000163359	tier1			72	0	0.00	32	23	41.82	21	0	0.00	19	24	55.81
ZNF230	0	genome.wustl.edu	37	19	44514834	44514835	+	Frame_Shift_Ins	INS	-	-	C			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	-	-	-	C	-	-	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	19	44514834	44514835	-	C	INS	ZNF230	ENST00000429154	human	ensembl	74_37	+1	known	frame_shift_ins	c.643_644	p.E215fs	0.009:0.003	pfscan_Znf_C2H2	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF230	HGNC	ENSG00000159882	tier1			136	0	0.00	63	38	37.62	8	0	0.00	8	8	50.00
TNR	0	genome.wustl.edu	37	1	175325480	175325480	+	Silent	SNP	G	G	A			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	1	175325480	175325480	G	A	SNP	TNR	ENST00000263525	human	ensembl	74_37	-1	known	silent	c.3093	p.G1031	1.000	superfamily_Fibronectin_type3,smart_Fibronectin_type3,pfscan_Fibronectin_type3	pfam_Fibronectin_type3,pfam_Fibrinogen_a/b/g_C_dom,pfam_EGF_extracell,superfamily_Fibrinogen_a/b/g_C_dom,superfamily_Fibronectin_type3,smart_EG-like_dom,smart_Fibronectin_type3,smart_Fibrinogen_a/b/g_C_dom,pfscan_Fibronectin_type3	-	no_errors	TNR	HGNC	ENSG00000116147	tier1	-	-	81	0	0.00	120	11	8.40	90	0	0.00	235	16	6.37
MMP16	0	genome.wustl.edu	37	8	89128891	89128891	+	Missense_Mutation	SNP	G	G	A			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	8	89128891	89128891	G	A	SNP	MMP16	ENST00000286614	human	ensembl	74_37	-1	known	missense	c.928	p.R310C	1.000	pirsf_Pept_M10A_Metazoans	pirsf_Pept_M10A_Metazoans,pfam_Hemopexin-like_repeat,pfam_Pept_M10_metallopeptidase,pfam_Pept_M10A_metallopeptidase_C,pfam_Peptidoglycan-bd-like,superfamily_Hemopexin-like_dom,superfamily_Peptidoglycan-bd-like,smart_Peptidase_Metallo,smart_Hemopexin-like_repeat,prints_Pept_M10A	-	no_errors	MMP16	HGNC	ENSG00000156103	tier1	rs202054317	GMAF=0.0005	99	0	0.00	65	31	32.29	44	1	2.22	50	28	35.44
SAA3P	0	genome.wustl.edu	37	11	18134251	18134251	+	R	SNP	C	C	T			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	11	18134251	18134251	C	T	SNP	SAA3P	ENST00000534768	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	SAA3P	HGNC	ENSG00000166787	tier1	-	-	66	0	0.00	32	20	38.46	39	1	2.50	33	44	57.14
OR12D2	0	genome.wustl.edu	37	6	29365079	29365079	+	Silent	SNP	G	G	T			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	6	29365079	29365079	G	T	SNP	OR12D2	ENST00000383555	human	ensembl	74_37	+1	known	silent	c.603	p.T201	0.000	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR12D2	HGNC	ENSG00000168787	tier1	-	-	57	0	0.00	14	22	61.11	55	0	0.00	25	41	62.12
PCMTD1	0	genome.wustl.edu	37	8	52732893	52732894	+	R	INS	-	-	C			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	8	52732893	52732894	-	C	INS	PCMTD1	ENST00000519559	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.206:0.021	-	-	-	no_errors	PCMTD1	HGNC	ENSG00000168300	tier1			52	0	0.00	65	8	10.96	12	0	0.00	5	0	0.00
SLC19A1	0	genome.wustl.edu	37	21	46951894	46951894	+	Nonsense_Mutation	SNP	G	G	A			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	21	46951894	46951894	G	A	SNP	SLC19A1	ENST00000311124	human	ensembl	74_37	-1	known	nonsense	c.358	p.Q120*	1.000	pfam_Folate_carrier,superfamily_MFS_dom_general_subst_transpt,pirsf_Folate_carrier,tigrfam_Folate_carrier	pfam_Folate_carrier,superfamily_MFS_dom_general_subst_transpt,pirsf_Folate_carrier,tigrfam_Folate_carrier	-	no_errors	SLC19A1	HGNC	ENSG00000173638	tier1	-	-	30	0	0.00	14	4	22.22	10	0	0.00	9	0	0.00
GOLGA6D	0	genome.wustl.edu	37	15	75585465	75585465	+	Missense_Mutation	SNP	C	C	T			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	15	75585465	75585465	C	T	SNP	GOLGA6D	ENST00000434739	human	ensembl	74_37	+1	known	missense	c.1553	p.T518M	0.000	NULL	NULL	-	no_errors	GOLGA6D	HGNC	ENSG00000140478	tier1	-	-	100	0	0.00	63	13	17.11	1	0	0.00	0	0	0.00
MIR3689B	0	genome.wustl.edu	37	9	137742041	137742041	+	R	SNP	G	G	A			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	9	137742041	137742041	G	A	SNP	MIR3689B	ENST00000581772	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	MIR3689B	HGNC	ENSG00000264163	tier1	rs35679521	-	69	0	0.00	61	9	12.68	0	0	0.00	2	0	0.00
ENSG00000261720	0	genome.wustl.edu	37	16	1116295	1116295	+	R	SNP	C	C	T			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	16	1116295	1116295	C	T	SNP	ENSG00000261720	ENST00000564390	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.319	-	-	-	no_errors	RP11-161M6.5	Clone_based_vega_gene	ENSG00000261720	tier1	-	-	14	0	0.00	6	13	68.42	0	0	0.00	2	2	50.00
ZNF534	0	genome.wustl.edu	37	19	52938381	52938381	+	Missense_Mutation	SNP	A	A	G			TCGA-IW-A3M6-01A-11D-A21Q-09	TCGA-IW-A3M6-10A-01D-A21Q-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	8529e1a2-7633-4494-b732-fcc8c189c723	a594b20f-78f1-4df9-a48b-24425afb78c3	19	52938381	52938381	A	G	SNP	ZNF534	ENST00000332323	human	ensembl	74_37	+1	known	missense	c.229	p.R77G	0.000	smart_Krueppel-associated_box,pfscan_Krueppel-associated_box	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF534	HGNC	ENSG00000198633	tier1	-	-	100	0	0.00	78	17	17.89	8	0	0.00	29	3	9.38