Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	default_gene_name	gene_name_source	 ensembl_gene_id	tier	dbSNP	GMAF	n_ref_count	n_alt_count	normal_vaf	t_ref_count	t_alt_count	tumor_vaf	n_ref_count_val	n_alt_count_val	normal_vaf_val	t_ref_count_val	t_alt_count_val	tumor_vaf_val
ZNF547	0	genome.wustl.edu	37	19	57889153	57889153	+	Missense_Mutation	SNP	G	G	T			TCGA-LI-A67I-01A-31D-A307-09	TCGA-LI-A67I-10A-01D-A307-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	002585e4-d695-47b6-af2c-3429073bc0b4	3f1693c5-913e-4965-a931-af97a11388c6	19	57889153	57889153	G	T	SNP	ZNF547	ENST00000282282	human	ensembl	74_37	+1	known	missense	c.809	p.C270F	0.321	smart_Znf_C2H2-like,pfscan_Znf_C2H2	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF547	HGNC	ENSG00000152433	tier1	-	-	112	0	0.00	65	16	19.75						
MSLNL	0	genome.wustl.edu	37	16	824427	824427	+	Missense_Mutation	SNP	G	G	A			TCGA-LI-A67I-01A-31D-A307-09	TCGA-LI-A67I-10A-01D-A307-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	002585e4-d695-47b6-af2c-3429073bc0b4	3f1693c5-913e-4965-a931-af97a11388c6	16	824427	824427	G	A	SNP	MSLNL	ENST00000293892	human	ensembl	74_37	-1	known	missense	c.1814	p.A605V	0.020	pfam_Mesothelin	pfam_Mesothelin	-	no_errors	MSLNL	HGNC	ENSG00000162006	tier1	-	-	15	0	0.00	9	10	52.63						
CCDC151	0	genome.wustl.edu	37	19	11537380	11537380	+	Silent	SNP	G	G	A			TCGA-LI-A67I-01A-31D-A307-09	TCGA-LI-A67I-10A-01D-A307-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	002585e4-d695-47b6-af2c-3429073bc0b4	3f1693c5-913e-4965-a931-af97a11388c6	19	11537380	11537380	G	A	SNP	CCDC151	ENST00000356392	human	ensembl	74_37	-1	known	silent	c.726	p.L242	0.012	NULL	NULL	-	no_errors	CCDC151	HGNC	ENSG00000198003	tier1	-	-	172	0	0.00	73	46	38.66						
PPP1R21	0	genome.wustl.edu	37	2	48734478	48734478	+	Missense_Mutation	SNP	C	C	T			TCGA-LI-A67I-01A-31D-A307-09	TCGA-LI-A67I-10A-01D-A307-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	002585e4-d695-47b6-af2c-3429073bc0b4	3f1693c5-913e-4965-a931-af97a11388c6	2	48734478	48734478	C	T	SNP	PPP1R21	ENST00000294952	human	ensembl	74_37	+1	known	missense	c.2039	p.S680F	0.923	pfam_KLRAQ/TTKRSYEDQ_C	pfam_KLRAQ/TTKRSYEDQ_C,pfam_Unchr_KLRAQ/TTKRSYEDQ_N,superfamily_Ferritin-like_SF	-	no_errors	PPP1R21	HGNC	ENSG00000162869	tier1	-	-	203	0	0.00	151	62	29.11						
PRRC2A	0	genome.wustl.edu	37	6	31599565	31599565	+	Missense_Mutation	SNP	C	C	T			TCGA-LI-A67I-01A-31D-A307-09	TCGA-LI-A67I-10A-01D-A307-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	002585e4-d695-47b6-af2c-3429073bc0b4	3f1693c5-913e-4965-a931-af97a11388c6	6	31599565	31599565	C	T	SNP	PRRC2A	ENST00000376007	human	ensembl	74_37	+1	known	missense	c.3115	p.R1039W	1.000	NULL	pfam_BAT2_N	-	no_errors	PRRC2A	HGNC	ENSG00000204469	tier1	-	-	161	1	0.61	110	38	25.68						
PLCD3	0	genome.wustl.edu	37	17	43196223	43196223	+	Missense_Mutation	SNP	C	C	T			TCGA-LI-A67I-01A-31D-A307-09	TCGA-LI-A67I-10A-01D-A307-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	002585e4-d695-47b6-af2c-3429073bc0b4	3f1693c5-913e-4965-a931-af97a11388c6	17	43196223	43196223	C	T	SNP	PLCD3	ENST00000322765	human	ensembl	74_37	-1	known	missense	c.872	p.R291H	0.405	pfam_PLipase_C_EF-hand-like	pfam_PLipase_C_PInositol-sp_X_dom,pfam_PLipase_C_Pinositol-sp_Y,pfam_PLipase_C_EF-hand-like,pfam_C2_dom,superfamily_PLC-like_Pdiesterase_TIM-brl,superfamily_C2_dom,smart_Pleckstrin_homology,smart_PLipase_C_PInositol-sp_X_dom,smart_PLipase_C_Pinositol-sp_Y,smart_C2_dom,pfscan_C2_dom,pfscan_PLipase_C_PInositol-sp_X_dom,pfscan_PLipase_C_Pinositol-sp_Y,prints_Pinositol_PLipase_C	-	no_errors	PLCD3	HGNC	ENSG00000161714	tier1	-	-	104	0	0.00	83	24	22.22						
ENSG00000225411	0	genome.wustl.edu	37	9	68400679	68400680	+	R	INS	-	-	AGCTA			TCGA-LI-A67I-01A-31D-A307-09	TCGA-LI-A67I-10A-01D-A307-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	002585e4-d695-47b6-af2c-3429073bc0b4	3f1693c5-913e-4965-a931-af97a11388c6	9	68400679	68400680	-	AGCTA	INS	ENSG00000225411	ENST00000417843	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.017:0.017	-	-	-	no_errors	RP11-764K9.1	Clone_based_vega_gene	ENSG00000225411	tier1														
FHL1	0	genome.wustl.edu	37	X	135291453	135291453	+	Missense_Mutation	SNP	C	C	A			TCGA-LI-A67I-01A-31D-A307-09	TCGA-LI-A67I-10A-01D-A307-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	002585e4-d695-47b6-af2c-3429073bc0b4	3f1693c5-913e-4965-a931-af97a11388c6	X	135291453	135291453	C	A	SNP	FHL1	ENST00000345434	human	ensembl	74_37	+1	known	missense	c.740	p.P247H	1.000	NULL	pfam_Znf_LIM,smart_Znf_LIM,pfscan_Znf_LIM	-	no_errors	FHL1	HGNC	ENSG00000022267	tier1	-	-	62	0	0.00	32	27	45.76						
MAML3	0	genome.wustl.edu	37	4	140641346	140641346	+	Missense_Mutation	SNP	C	C	T			TCGA-LI-A67I-01A-31D-A307-09	TCGA-LI-A67I-10A-01D-A307-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	002585e4-d695-47b6-af2c-3429073bc0b4	3f1693c5-913e-4965-a931-af97a11388c6	4	140641346	140641346	C	T	SNP	MAML3	ENST00000509479	human	ensembl	74_37	-1	known	missense	c.2548	p.A850T	0.170	NULL	pfam_Neuroggenic_mastermind-like_N	-	no_errors	MAML3	HGNC	ENSG00000196782	tier1	-	-	68	0	0.00	14	56	80.00						
CPSF7	0	genome.wustl.edu	37	11	61188968	61188968	+	Missense_Mutation	SNP	C	C	T			TCGA-LI-A67I-01A-31D-A307-09	TCGA-LI-A67I-10A-01D-A307-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	002585e4-d695-47b6-af2c-3429073bc0b4	3f1693c5-913e-4965-a931-af97a11388c6	11	61188968	61188968	C	T	SNP	CPSF7	ENST00000340437	human	ensembl	74_37	-1	known	missense	c.296	p.R99H	1.000	NULL	pfam_RRM_dom,smart_RRM_dom,pfscan_RRM_dom	-	no_errors	CPSF7	HGNC	ENSG00000149532	tier1	rs200597857	-	200	0	0.00	102	68	40.00						
GSPT2	0	genome.wustl.edu	37	X	51486909	51486909	+	Missense_Mutation	SNP	G	G	A			TCGA-LI-A67I-01A-31D-A307-09	TCGA-LI-A67I-10A-01D-A307-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	002585e4-d695-47b6-af2c-3429073bc0b4	3f1693c5-913e-4965-a931-af97a11388c6	X	51486909	51486909	G	A	SNP	GSPT2	ENST00000340438	human	ensembl	74_37	+1	known	missense	c.187	p.V63I	0.998	pfam_Ataxin-2_C	pfam_EF_GTP-bd_dom,pfam_Transl_elong_EFTu/EF1A_C,pfam_Transl_elong_EFTu/EF1A_2,pfam_Ataxin-2_C,superfamily_P-loop_NTPase,superfamily_Transl_elong_EF1A/Init_IF2_C,superfamily_Transl_B-barrel,prints_EF_GTP-bd_dom	-	no_errors	GSPT2	HGNC	ENSG00000189369	tier1	-	-	131	1	0.76	56	35	38.46						
KIF19	0	genome.wustl.edu	37	17	72346862	72346862	+	Missense_Mutation	SNP	T	T	A			TCGA-LI-A67I-01A-31D-A307-09	TCGA-LI-A67I-10A-01D-A307-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	002585e4-d695-47b6-af2c-3429073bc0b4	3f1693c5-913e-4965-a931-af97a11388c6	17	72346862	72346862	T	A	SNP	KIF19	ENST00000389916	human	ensembl	74_37	+1	known	missense	c.1405	p.S469T	0.594	NULL	pfam_Kinesin_motor_dom,superfamily_P-loop_NTPase,smart_Kinesin_motor_dom,prints_Kinesin_motor_dom,pfscan_Kinesin_motor_dom	-	no_errors	KIF19	HGNC	ENSG00000196169	tier1	-	-	169	0	0.00	88	72	43.64						
PTEN	0	genome.wustl.edu	37	10	89685305	89685305	+	Missense_Mutation	SNP	T	T	A			TCGA-LI-A67I-01A-31D-A307-09	TCGA-LI-A67I-10A-01D-A307-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	002585e4-d695-47b6-af2c-3429073bc0b4	3f1693c5-913e-4965-a931-af97a11388c6	10	89685305	89685305	T	A	SNP	PTEN	ENST00000371953	human	ensembl	74_37	+1	known	missense	c.200	p.I67K	1.000	pfam_Tyr_Pase_rcpt/non-rcpt,smart_Tyr_Pase_cat,pirsf_Bifunc_PIno_P3_Pase/Pase_PTEN,pfscan_Phosphatase_tensin-typ	pfam_Tensin_phosphatase_C2-dom,pfam_Dual-sp_phosphatase_cat-dom,pfam_Tyr_Pase_rcpt/non-rcpt,superfamily_C2_dom,smart_Tyr_Pase_cat,pirsf_Bifunc_PIno_P3_Pase/Pase_PTEN,pfscan_Tyr/Dual-sp_Pase,pfscan_Phosphatase_tensin-typ,pfscan_Tensin_phosphatase_C2-dom	-	no_errors	PTEN	HGNC	ENSG00000171862	tier1	-	-	166	0	0.00	29	104	78.20						
SYK	0	genome.wustl.edu	37	9	93624510	93624510	+	Missense_Mutation	SNP	G	G	A			TCGA-LI-A67I-01A-31D-A307-09	TCGA-LI-A67I-10A-01D-A307-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	002585e4-d695-47b6-af2c-3429073bc0b4	3f1693c5-913e-4965-a931-af97a11388c6	9	93624510	93624510	G	A	SNP	SYK	ENST00000375746	human	ensembl	74_37	+1	known	missense	c.601	p.G201S	1.000	pfam_SH2,smart_SH2,pirsf_Tyr_kinase_non-rcpt_SYK/ZAP70,pfscan_SH2,prints_SH2	pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_kinase_dom,pfam_SH2,superfamily_Kinase-like_dom,smart_SH2,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pirsf_Tyr_kinase_non-rcpt_SYK/ZAP70,pfscan_SH2,pfscan_Prot_kinase_dom,prints_Ser-Thr/Tyr_kinase_cat_dom,prints_SH2	-	no_errors	SYK	HGNC	ENSG00000165025	tier1	-	-	127	0	0.00	79	78	49.37						
RTL1	0	genome.wustl.edu	37	14	101348435	101348435	+	Silent	SNP	G	G	A			TCGA-LI-A67I-01A-31D-A307-09	TCGA-LI-A67I-10A-01D-A307-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	002585e4-d695-47b6-af2c-3429073bc0b4	3f1693c5-913e-4965-a931-af97a11388c6	14	101348435	101348435	G	A	SNP	RTL1	ENST00000534062	human	ensembl	74_37	-1	known	silent	c.2691	p.T897	0.000	NULL	pfam_Retrotrans_gag_dom,superfamily_Peptidase_aspartic_dom	-	no_errors	RTL1	HGNC	ENSG00000254656	tier1	-	-	133	1	0.75	62	28	31.11						
DCAF8L2	0	genome.wustl.edu	37	X	27765400	27765408	+	In_Frame_Del	DEL	GAGGAGGAG	GAGGAGGAG	-			TCGA-LI-A67I-01A-31D-A307-09	TCGA-LI-A67I-10A-01D-A307-09	GAGGAGGAG	GAGGAGGAG					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	002585e4-d695-47b6-af2c-3429073bc0b4	3f1693c5-913e-4965-a931-af97a11388c6	X	27765400	27765408	GAGGAGGAG	-	DEL	DCAF8L2	ENST00000451261	human	ensembl	74_37	+1	known	in_frame_del	c.388_396	p.EEE133in_frame_del	0.007:0.003:0.002:0.002:0.001:0.000:0.000:0.000:0.000	NULL	pfam_WD40_repeat,superfamily_WD40_repeat_dom,smart_WD40_repeat,pfscan_WD40_repeat,pfscan_WD40_repeat_dom	-	no_errors	DCAF8L2	HGNC	ENSG00000189186	tier1														
PCDH12	0	genome.wustl.edu	37	5	141335172	141335172	+	Missense_Mutation	SNP	C	C	T			TCGA-LI-A67I-01A-31D-A307-09	TCGA-LI-A67I-10A-01D-A307-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	002585e4-d695-47b6-af2c-3429073bc0b4	3f1693c5-913e-4965-a931-af97a11388c6	5	141335172	141335172	C	T	SNP	PCDH12	ENST00000231484	human	ensembl	74_37	-1	known	missense	c.2245	p.A749T	1.000	NULL	pfam_Cadherin,pfam_Cadherin_N,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin,prints_Cadherin	-	no_errors	PCDH12	HGNC	ENSG00000113555	tier1	-	-	76	0	0.00	55	6	9.84						
DDX41	0	genome.wustl.edu	37	5	176938889	176938889	+	Missense_Mutation	SNP	C	C	T			TCGA-LI-A67I-01A-31D-A307-09	TCGA-LI-A67I-10A-01D-A307-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	002585e4-d695-47b6-af2c-3429073bc0b4	3f1693c5-913e-4965-a931-af97a11388c6	5	176938889	176938889	C	T	SNP	DDX41	ENST00000507955	human	ensembl	74_37	-1	known	missense	c.1772	p.R591Q	0.999	superfamily_Znf_CCHC	pfam_D/R_helicase_DEAD/DEAH_N,pfam_Helicase_C,superfamily_P-loop_NTPase,superfamily_Znf_CCHC,smart_Helicase_ATP-bd,smart_Helicase_C,pfscan_Helicase_ATP-bd,pfscan_Helicase_C,pfscan_R_helicase_DEAD_Q_motif	-	no_errors	DDX41	HGNC	ENSG00000183258	tier1	-	-	87	0	0.00	53	49	48.04						
CCDC19	0	genome.wustl.edu	37	1	159846347	159846347	+	Missense_Mutation	SNP	G	G	A			TCGA-LI-A67I-01A-31D-A307-09	TCGA-LI-A67I-10A-01D-A307-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	002585e4-d695-47b6-af2c-3429073bc0b4	3f1693c5-913e-4965-a931-af97a11388c6	1	159846347	159846347	G	A	SNP	CCDC19	ENST00000368099	human	ensembl	74_37	-1	known	missense	c.1351	p.R451W	1.000	NULL	NULL	-	no_errors	CCDC19	HGNC	ENSG00000213085	tier1	-	-	109	1	0.91	18	56	75.68						
IDO1	0	genome.wustl.edu	37	8	39776355	39776355	+	Missense_Mutation	SNP	G	G	C			TCGA-LI-A67I-01A-31D-A307-09	TCGA-LI-A67I-10A-01D-A307-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	002585e4-d695-47b6-af2c-3429073bc0b4	3f1693c5-913e-4965-a931-af97a11388c6	8	39776355	39776355	G	C	SNP	IDO1	ENST00000518237	human	ensembl	74_37	+1	known	missense	c.325	p.V109L	0.461	pfam_Indolamine_dOase	pfam_Indolamine_dOase	-	no_errors	IDO1	HGNC	ENSG00000131203	tier1	-	-	174	0	0.00	83	32	27.83						
AK9	0	genome.wustl.edu	37	6	109996917	109996917	+	Missense_Mutation	SNP	G	G	A			TCGA-LI-A67I-01A-31D-A307-09	TCGA-LI-A67I-10A-01D-A307-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	002585e4-d695-47b6-af2c-3429073bc0b4	3f1693c5-913e-4965-a931-af97a11388c6	6	109996917	109996917	G	A	SNP	AK9	ENST00000424296	human	ensembl	74_37	-1	known	missense	c.32	p.P11L	0.999	NULL	pfam_Adenylate_kin,pfam_YHS_dom,superfamily_P-loop_NTPase,smart_AAA+_ATPase	-	no_errors	AK9	HGNC	ENSG00000155085	tier1	-	-	204	0	0.00	161	101	38.55						
AHK	0	genome.wustl.edu	37	11	62294150	62294150	+	Missense_Mutation	SNP	G	G	A			TCGA-LI-A67I-01A-31D-A307-09	TCGA-LI-A67I-10A-01D-A307-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	002585e4-d695-47b6-af2c-3429073bc0b4	3f1693c5-913e-4965-a931-af97a11388c6	11	62294150	62294150	G	A	SNP	AHK	ENST00000378024	human	ensembl	74_37	-1	known	missense	c.7739	p.S2580F	1.000	NULL	superfamily_PDZ,smart_PDZ,pfscan_PDZ	-	no_errors	AHK	HGNC	ENSG00000124942	tier1	-	-	345	0	0.00	249	28	10.11						
MUC16	0	genome.wustl.edu	37	19	9076876	9076876	+	Missense_Mutation	SNP	C	C	T			TCGA-LI-A67I-01A-31D-A307-09	TCGA-LI-A67I-10A-01D-A307-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	002585e4-d695-47b6-af2c-3429073bc0b4	3f1693c5-913e-4965-a931-af97a11388c6	19	9076876	9076876	C	T	SNP	MUC16	ENST00000397910	human	ensembl	74_37	-1	known	missense	c.10570	p.E3524K	0.000	NULL	pfam_SEA_dom,smart_SEA_dom,pfscan_SEA_dom	-	no_errors	MUC16	HGNC	ENSG00000181143	tier1	-	-	265	0	0.00	112	79	41.36						
VPS51	0	genome.wustl.edu	37	11	64877351	64877351	+	Missense_Mutation	SNP	G	G	A			TCGA-LI-A67I-01A-31D-A307-09	TCGA-LI-A67I-10A-01D-A307-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	002585e4-d695-47b6-af2c-3429073bc0b4	3f1693c5-913e-4965-a931-af97a11388c6	11	64877351	64877351	G	A	SNP	VPS51	ENST00000279281	human	ensembl	74_37	+1	known	missense	c.1834	p.V612I	1.000	NULL	pfam_COG8,pfam_Vacuolar_sorting-assoc_54,pfam_COG_su2_N,pfam_RZZ-complex_Zw10,superfamily_Cullin_repeat-like_dom	-	no_errors	VPS51	HGNC	ENSG00000149823	tier1	-	-	162	0	0.00	35	48	57.83						
BCL11A	0	genome.wustl.edu	37	2	60688425	60688425	+	Missense_Mutation	SNP	C	C	T			TCGA-LI-A67I-01A-31D-A307-09	TCGA-LI-A67I-10A-01D-A307-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	002585e4-d695-47b6-af2c-3429073bc0b4	3f1693c5-913e-4965-a931-af97a11388c6	2	60688425	60688425	C	T	SNP	BCL11A	ENST00000335712	human	ensembl	74_37	-1	known	missense	c.1622	p.R541H	1.000	NULL	pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2	-	no_errors	BCL11A	HGNC	ENSG00000119866	tier1	-	-	22	0	0.00	7	12	63.16						
DCHS1	0	genome.wustl.edu	37	11	6643466	6643466	+	Silent	SNP	C	C	G			TCGA-LI-A67I-01A-31D-A307-09	TCGA-LI-A67I-10A-01D-A307-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	002585e4-d695-47b6-af2c-3429073bc0b4	3f1693c5-913e-4965-a931-af97a11388c6	11	6643466	6643466	C	G	SNP	DCHS1	ENST00000299441	human	ensembl	74_37	-1	known	silent	c.9441	p.L3147	0.998	NULL	pfam_Cadherin,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin,prints_Cadherin	-	no_errors	DCHS1	HGNC	ENSG00000166341	tier1	-	-	83	0	0.00	12	47	79.66						
GLIS1	0	genome.wustl.edu	37	1	54060320	54060320	+	Missense_Mutation	SNP	C	C	T			TCGA-LI-A67I-01A-31D-A307-09	TCGA-LI-A67I-10A-01D-A307-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	002585e4-d695-47b6-af2c-3429073bc0b4	3f1693c5-913e-4965-a931-af97a11388c6	1	54060320	54060320	C	T	SNP	GLIS1	ENST00000312233	human	ensembl	74_37	-1	known	missense	c.256	p.V86I	0.002	NULL	smart_Znf_C2H2-like,pfscan_Znf_C2H2	-	no_errors	GLIS1	HGNC	ENSG00000174332	tier1	-	-	160	0	0.00	129	110	45.83						
ENSG00000206195	0	genome.wustl.edu	37	22	16150827	16150827	+	R	SNP	C	C	T			TCGA-LI-A67I-01A-31D-A307-09	TCGA-LI-A67I-10A-01D-A307-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	002585e4-d695-47b6-af2c-3429073bc0b4	3f1693c5-913e-4965-a931-af97a11388c6	22	16150827	16150827	C	T	SNP	ENSG00000206195	ENST00000413768	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.027	-	-	-	no_errors	AP000525.9	Clone_based_vega_gene	ENSG00000206195	tier1	rs199764989	-	12	0	0.00	6	4	40.00						
SOX17	0	genome.wustl.edu	37	8	55372529	55372529	+	Missense_Mutation	SNP	T	T	C			TCGA-LI-A67I-01A-31D-A307-09	TCGA-LI-A67I-10A-01D-A307-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	002585e4-d695-47b6-af2c-3429073bc0b4	3f1693c5-913e-4965-a931-af97a11388c6	8	55372529	55372529	T	C	SNP	SOX17	ENST00000297316	human	ensembl	74_37	+1	known	missense	c.1219	p.Y407H	0.998	pfam_Sox_C_TAD	pfam_Sox_C_TAD,pfam_HMG_box_dom,superfamily_HMG_box_dom,smart_HMG_box_dom,pfscan_HMG_box_dom	-	no_errors	SOX17	HGNC	ENSG00000164736	tier1	-	-	93	0	0.00	56	23	29.11						
ZNF519	0	genome.wustl.edu	37	18	14105364	14105364	+	Missense_Mutation	SNP	G	G	A			TCGA-LI-A67I-01A-31D-A307-09	TCGA-LI-A67I-10A-01D-A307-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	002585e4-d695-47b6-af2c-3429073bc0b4	3f1693c5-913e-4965-a931-af97a11388c6	18	14105364	14105364	G	A	SNP	ZNF519	ENST00000590202	human	ensembl	74_37	-1	known	missense	c.1175	p.T392I	0.000	pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF519	HGNC	ENSG00000175322	tier1	-	-	104	0	0.00	62	62	50.00						
ENSG00000273312	0	genome.wustl.edu	37	10	35896211	35896212	+	R	INS	-	-	TGCTCT			TCGA-LI-A67I-01A-31D-A307-09	TCGA-LI-A67I-10A-01D-A307-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	002585e4-d695-47b6-af2c-3429073bc0b4	3f1693c5-913e-4965-a931-af97a11388c6	10	35896211	35896212	-	TGCTCT	INS	ENSG00000273312	ENST00000609313	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000:0.000	-	-	-	no_errors	RP11-425A6.5	Clone_based_vega_gene	ENSG00000273312	tier1														
TM4SF1	0	genome.wustl.edu	37	3	149093526	149093526	+	Missense_Mutation	SNP	G	G	T			TCGA-LI-A67I-01A-31D-A307-09	TCGA-LI-A67I-10A-01D-A307-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	002585e4-d695-47b6-af2c-3429073bc0b4	3f1693c5-913e-4965-a931-af97a11388c6	3	149093526	149093526	G	T	SNP	TM4SF1	ENST00000305366	human	ensembl	74_37	-1	known	missense	c.208	p.L70M	0.536	pfam_L6_membrane	pfam_L6_membrane	-	no_errors	TM4SF1	HGNC	ENSG00000169908	tier1	-	-	55	0	0.00	21	15	41.67						
DCHS1	0	genome.wustl.edu	37	11	6653374	6653374	+	Silent	SNP	G	G	A			TCGA-LI-A67I-01A-31D-A307-09	TCGA-LI-A67I-10A-01D-A307-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	002585e4-d695-47b6-af2c-3429073bc0b4	3f1693c5-913e-4965-a931-af97a11388c6	11	6653374	6653374	G	A	SNP	DCHS1	ENST00000299441	human	ensembl	74_37	-1	known	silent	c.3369	p.S1123	0.895	pfam_Cadherin,superfamily_Cadherin-like,pfscan_Cadherin	pfam_Cadherin,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin,prints_Cadherin	-	no_errors	DCHS1	HGNC	ENSG00000166341	tier1	-	-	107	0	0.00	13	59	80.82						
AP1AR	0	genome.wustl.edu	37	4	113189426	113189439	+	Frame_Shift_Del	DEL	GGCTGGAGTGGGAA	GGCTGGAGTGGGAA	-			TCGA-LI-A67I-01A-31D-A307-09	TCGA-LI-A67I-10A-01D-A307-09	GGCTGGAGTGGGAA	GGCTGGAGTGGGAA					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	002585e4-d695-47b6-af2c-3429073bc0b4	3f1693c5-913e-4965-a931-af97a11388c6	4	113189426	113189439	GGCTGGAGTGGGAA	-	DEL	AP1AR	ENST00000274000	human	ensembl	74_37	+1	known	frame_shift_del	c.770_783	p.G257fs	1.000:0.976:0.999:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000	NULL	NULL	-	no_errors	AP1AR	HGNC	ENSG00000138660	tier1														
TP53	0	genome.wustl.edu	37	17	7578213	7578213	+	Frame_Shift_Del	DEL	A	A	-			TCGA-LI-A67I-01A-31D-A307-09	TCGA-LI-A67I-10A-01D-A307-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	002585e4-d695-47b6-af2c-3429073bc0b4	3f1693c5-913e-4965-a931-af97a11388c6	17	7578213	7578213	A	-	DEL	TP53	ENST00000269305	human	ensembl	74_37	-1	known	frame_shift_del	c.636	p.R213fs	0.000	pfam_p53_D-bd,superfamily_p53-like_TF_D-bd,prints_p53_tumour_suppressor	pfam_p53_D-bd,pfam_p53_tetrameristn,pfam_p53_transactivation_domain,superfamily_p53-like_TF_D-bd,superfamily_p53_tetrameristn,prints_p53_tumour_suppressor	-	no_errors	TP53	HGNC	ENSG00000141510	tier1			121	0	0.00	31	94	75.20						
HTATIP2	0	genome.wustl.edu	37	11	20385381	20385382	+	In_Frame_Ins	INS	-	-	GCGGCG			TCGA-LI-A67I-01A-31D-A307-09	TCGA-LI-A67I-10A-01D-A307-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	002585e4-d695-47b6-af2c-3429073bc0b4	3f1693c5-913e-4965-a931-af97a11388c6	11	20385381	20385382	-	GCGGCG	INS	HTATIP2	ENST00000419348	human	ensembl	74_37	+1	known	in_frame_ins	c.24_25	p.12in_frame_insAA	0.320:0.178	NULL	pfam_Semialdehyde_DH_D-bd	-	no_errors	HTATIP2	HGNC	ENSG00000109854	tier1														
FRMPD1	0	genome.wustl.edu	37	9	37744414	37744414	+	Silent	SNP	C	C	A			TCGA-LI-A67I-01A-31D-A307-09	TCGA-LI-A67I-10A-01D-A307-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	002585e4-d695-47b6-af2c-3429073bc0b4	3f1693c5-913e-4965-a931-af97a11388c6	9	37744414	37744414	C	A	SNP	FRMPD1	ENST00000377765	human	ensembl	74_37	+1	known	silent	c.2385	p.P795	0.144	NULL	pfam_FERM_central,pfam_PDZ,pfam_FERM_N,superfamily_FERM_central,superfamily_PDZ,smart_PDZ,smart_Band_41_domain,pfscan_FERM_domain,pfscan_PDZ	-	no_errors	FRMPD1	HGNC	ENSG00000070601	tier1	-	-	207	0	0.00	171	106	38.27						
PSMC3IP	0	genome.wustl.edu	37	17	40725008	40725008	+	Missense_Mutation	SNP	T	T	G			TCGA-LI-A67I-01A-31D-A307-09	TCGA-LI-A67I-10A-01D-A307-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	002585e4-d695-47b6-af2c-3429073bc0b4	3f1693c5-913e-4965-a931-af97a11388c6	17	40725008	40725008	T	G	SNP	PSMC3IP	ENST00000393795	human	ensembl	74_37	-1	known	missense	c.632	p.N211T	0.040	NULL	pfam_TBPIP,pfam_BlaI_family	-	no_errors	PSMC3IP	HGNC	ENSG00000131470	tier1	-	-	79	0	0.00	50	28	35.90						
USP27X-AS1	0	genome.wustl.edu	37	X	49641821	49641821	+	R	SNP	C	C	G			TCGA-LI-A67I-01A-31D-A307-09	TCGA-LI-A67I-10A-01D-A307-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	002585e4-d695-47b6-af2c-3429073bc0b4	3f1693c5-913e-4965-a931-af97a11388c6	X	49641821	49641821	C	G	SNP	USP27X-AS1	ENST00000437322	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	USP27X-AS1	HGNC	ENSG00000234390	tier1	-	-	39	0	0.00	12	11	47.83						
GCM1	0	genome.wustl.edu	37	6	52993032	52993032	+	Missense_Mutation	SNP	A	A	G			TCGA-LI-A67I-01A-31D-A307-09	TCGA-LI-A67I-10A-01D-A307-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	002585e4-d695-47b6-af2c-3429073bc0b4	3f1693c5-913e-4965-a931-af97a11388c6	6	52993032	52993032	A	G	SNP	GCM1	ENST00000259803	human	ensembl	74_37	-1	known	missense	c.1283	p.M428T	0.761	NULL	pfam_Tscrpt_reg_GCM_motif,superfamily_Tscrpt_reg_GCM_motif,pfscan_Tscrpt_reg_GCM_motif	-	no_errors	GCM1	HGNC	ENSG00000137270	tier1	-	-	79	0	0.00	68	50	42.37						
MAP3K7CL	0	genome.wustl.edu	37	21	30505648	30505648	+	Missense_Mutation	SNP	G	G	A			TCGA-LI-A67I-01A-31D-A307-09	TCGA-LI-A67I-10A-01D-A307-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	002585e4-d695-47b6-af2c-3429073bc0b4	3f1693c5-913e-4965-a931-af97a11388c6	21	30505648	30505648	G	A	SNP	MAP3K7CL	ENST00000286791	human	ensembl	74_37	+1	known	missense	c.392	p.R131Q	0.025	NULL	NULL	-	no_errors	MAP3K7CL	HGNC	ENSG00000156265	tier1	-	-	110	0	0.00	96	74	43.53						
XKR7	0	genome.wustl.edu	37	20	30584527	30584527	+	Missense_Mutation	SNP	G	G	T			TCGA-LI-A67I-01A-31D-A307-09	TCGA-LI-A67I-10A-01D-A307-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	002585e4-d695-47b6-af2c-3429073bc0b4	3f1693c5-913e-4965-a931-af97a11388c6	20	30584527	30584527	G	T	SNP	XKR7	ENST00000562532	human	ensembl	74_37	+1	known	missense	c.1007	p.W336L	1.000	pfam_Transport_prot_XK	pfam_Transport_prot_XK	-	no_errors	XKR7	HGNC	ENSG00000260903	tier1	-	-	73	0	0.00	12	44	78.57						
SCN5A	0	genome.wustl.edu	37	3	38592282	38592282	+	Missense_Mutation	SNP	C	C	A			TCGA-LI-A67I-01A-31D-A307-09	TCGA-LI-A67I-10A-01D-A307-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	002585e4-d695-47b6-af2c-3429073bc0b4	3f1693c5-913e-4965-a931-af97a11388c6	3	38592282	38592282	C	A	SNP	SCN5A	ENST00000333535	human	ensembl	74_37	-1	known	missense	c.5581	p.V1861F	1.000	NULL	pfam_Ion_trans_dom,pfam_Na_trans_assoc,pfam_DUF3451,pfam_PKD1_2_channel,prints_Na_channel_a5su,prints_Na_channel_asu	-	no_errors	SCN5A	HGNC	ENSG00000183873	tier1	-	-	265	1	0.38	111	84	43.08						
SSBP3	0	genome.wustl.edu	37	1	54691919	54691920	+	R	INS	-	-	GAA			TCGA-LI-A67I-01A-31D-A307-09	TCGA-LI-A67I-10A-01D-A307-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	002585e4-d695-47b6-af2c-3429073bc0b4	3f1693c5-913e-4965-a931-af97a11388c6	1	54691919	54691920	-	GAA	INS	SSBP3	ENST00000326956	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.706:0.379	-	-	-	no_errors	SSBP3	HGNC	ENSG00000157216	tier1			10	0	0.00	6	5	45.45						
DOCK1	0	genome.wustl.edu	37	10	129231688	129231688	+	Missense_Mutation	SNP	G	G	T			TCGA-LI-A67I-01A-31D-A307-09	TCGA-LI-A67I-10A-01D-A307-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	002585e4-d695-47b6-af2c-3429073bc0b4	3f1693c5-913e-4965-a931-af97a11388c6	10	129231688	129231688	G	T	SNP	DOCK1	ENST00000280333	human	ensembl	74_37	+1	known	missense	c.4993	p.D1665Y	0.999	NULL	pfam_DOCK_C,pfam_SH3_domain,pfam_SH3_2,superfamily_SH3_domain,superfamily_ARM-type_fold,superfamily_Cyt_c-like_dom,smart_SH3_domain,pfscan_SH3_domain	-	no_errors	DOCK1	HGNC	ENSG00000150760	tier1	-	-	142	0	0.00	16	76	82.61						
ARHGEF7	0	genome.wustl.edu	37	13	111955453	111955453	+	Missense_Mutation	SNP	A	A	G			TCGA-LI-A67I-01A-31D-A307-09	TCGA-LI-A67I-10A-01D-A307-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	002585e4-d695-47b6-af2c-3429073bc0b4	3f1693c5-913e-4965-a931-af97a11388c6	13	111955453	111955453	A	G	SNP	ARHGEF7	ENST00000370623	human	ensembl	74_37	+1	known	missense	c.2189	p.N730S	1.000	NULL	pfam_DH-domain,pfam_SH3_2,pfam_SH3_domain,pfam_Pleckstrin_homology,pfam_CH-domain,superfamily_DH-domain,superfamily_SH3_domain,superfamily_CH-domain,smart_CH-domain,smart_SH3_domain,smart_DH-domain,smart_Pleckstrin_homology,pfscan_CH-domain,pfscan_Pleckstrin_homology,pfscan_SH3_domain,pfscan_DH-domain,prints_SH3_domain	-	no_errors	ARHGEF7	HGNC	ENSG00000102606	tier1	-	-	79	0	0.00	12	52	81.25						
CDKN2D	0	genome.wustl.edu	37	19	10677946	10677946	+	Missense_Mutation	SNP	C	C	A			TCGA-LI-A67I-01A-31D-A307-09	TCGA-LI-A67I-10A-01D-A307-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	002585e4-d695-47b6-af2c-3429073bc0b4	3f1693c5-913e-4965-a931-af97a11388c6	19	10677946	10677946	C	A	SNP	CDKN2D	ENST00000335766	human	ensembl	74_37	-1	known	missense	c.289	p.G97W	0.998	pfam_Ankyrin_rpt,superfamily_Ankyrin_rpt-contain_dom,smart_Ankyrin_rpt,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom	pfam_Ankyrin_rpt,superfamily_Ankyrin_rpt-contain_dom,smart_Ankyrin_rpt,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom	-	no_errors	CDKN2D	HGNC	ENSG00000129355	tier1	-	-	67	0	0.00	47	18	27.69						
NSUN5P1	0	genome.wustl.edu	37	7	75044036	75044036	+	R	SNP	C	C	T			TCGA-LI-A67I-01A-31D-A307-09	TCGA-LI-A67I-10A-01D-A307-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	002585e4-d695-47b6-af2c-3429073bc0b4	3f1693c5-913e-4965-a931-af97a11388c6	7	75044036	75044036	C	T	SNP	NSUN5P1	ENST00000393633	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.037	-	-	-	no_errors	NSUN5P1	HGNC	ENSG00000223705	tier1	-	-	45	0	0.00	10	42	80.77						
RB1	0	genome.wustl.edu	37	13	49039415	49039415	+	Frame_Shift_Del	DEL	T	T	-			TCGA-LI-A67I-01A-31D-A307-09	TCGA-LI-A67I-10A-01D-A307-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	002585e4-d695-47b6-af2c-3429073bc0b4	3f1693c5-913e-4965-a931-af97a11388c6	13	49039415	49039415	T	-	DEL	RB1	ENST00000267163	human	ensembl	74_37	+1	known	frame_shift_del	c.2400	p.G801fs	1.000	pfam_RB_C	pfam_RB_C,pfam_RB_A,pfam_RB_B,pfam_RB_N,superfamily_Cyclin-like,smart_Cyclin-like	-	no_errors	RB1	HGNC	ENSG00000139687	tier1			85	0	0.00	29	32	52.46						
WBP2NL	0	genome.wustl.edu	37	22	42398850	42398854	+	R	DEL	TACTT	TACTT	-			TCGA-LI-A67I-01A-31D-A307-09	TCGA-LI-A67I-10A-01D-A307-09	TACTT	TACTT					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	002585e4-d695-47b6-af2c-3429073bc0b4	3f1693c5-913e-4965-a931-af97a11388c6	22	42398850	42398854	TACTT	-	DEL	WBP2NL	ENST00000461730	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.001:0.003:0.012:0.016:0.015	-	-	-	no_errors	WBP2NL	HGNC	ENSG00000183066	tier1														
RIMS2	0	genome.wustl.edu	37	8	105235995	105235995	+	Missense_Mutation	SNP	T	T	A			TCGA-LI-A67I-01A-31D-A307-09	TCGA-LI-A67I-10A-01D-A307-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	002585e4-d695-47b6-af2c-3429073bc0b4	3f1693c5-913e-4965-a931-af97a11388c6	8	105235995	105235995	T	A	SNP	RIMS2	ENST00000339750	human	ensembl	74_37	+1	known	missense	c.116	p.M39K	1.000	NULL	pfam_C2_dom,superfamily_C2_dom,smart_C2_dom,pfscan_C2_dom	-	no_errors	RIMS2	HGNC	ENSG00000176406	tier1	-	-	178	0	0.00	81	50	38.17						
ANKRD20A5P	0	genome.wustl.edu	37	18	14179480	14179480	+	R	SNP	C	C	G			TCGA-LI-A67I-01A-31D-A307-09	TCGA-LI-A67I-10A-01D-A307-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	002585e4-d695-47b6-af2c-3429073bc0b4	3f1693c5-913e-4965-a931-af97a11388c6	18	14179480	14179480	C	G	SNP	ANKRD20A5P	ENST00000581181	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.001	-	-	-	no_errors	ANKRD20A5P	HGNC	ENSG00000186481	tier1	-	-	216	0	0.00	190	72	27.38						
UGT2B11	0	genome.wustl.edu	37	4	70079984	70079984	+	Missense_Mutation	SNP	C	C	G			TCGA-LI-A67I-01A-31D-A307-09	TCGA-LI-A67I-10A-01D-A307-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	002585e4-d695-47b6-af2c-3429073bc0b4	3f1693c5-913e-4965-a931-af97a11388c6	4	70079984	70079984	C	G	SNP	UGT2B11	ENST00000446444	human	ensembl	74_37	-1	known	missense	c.457	p.V153L	0.000	pfam_UDP_glucos_trans	pfam_UDP_glucos_trans,pfam_Glyco_trans_28_C	-	no_errors	UGT2B11	HGNC	ENSG00000213759	tier1	rs139371276	-	250	0	0.00	57	178	75.74						
ABCC3	0	genome.wustl.edu	37	17	48760996	48760996	+	Missense_Mutation	SNP	G	G	A			TCGA-LI-A67I-01A-31D-A307-09	TCGA-LI-A67I-10A-01D-A307-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	002585e4-d695-47b6-af2c-3429073bc0b4	3f1693c5-913e-4965-a931-af97a11388c6	17	48760996	48760996	G	A	SNP	ABCC3	ENST00000285238	human	ensembl	74_37	+1	known	missense	c.3833	p.R1278H	0.708	superfamily_P-loop_NTPase,tigrfam_Multidrug-R_assoc	pfam_ABC_transptr_TM_dom,pfam_ABC_transporter-like,superfamily_ABC1_TM_dom,superfamily_P-loop_NTPase,smart_AAA+_ATPase,pfscan_ABC_transporter-like,pfscan_ABC1_TM_dom,tigrfam_Multidrug-R_assoc	-	no_errors	ABCC3	HGNC	ENSG00000108846	tier1	-	-	170	1	0.58	66	97	59.51						
ITGA1	0	genome.wustl.edu	37	5	52177853	52177853	+	Missense_Mutation	SNP	G	G	T			TCGA-LI-A67I-01A-31D-A307-09	TCGA-LI-A67I-10A-01D-A307-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	002585e4-d695-47b6-af2c-3429073bc0b4	3f1693c5-913e-4965-a931-af97a11388c6	5	52177853	52177853	G	T	SNP	ITGA1	ENST00000282588	human	ensembl	74_37	+1	known	missense	c.773	p.R258I	1.000	pfam_VWF_A,smart_VWF_A,pfscan_VWF_A	pfam_Integrin_alpha-2,pfam_VWF_A,pfam_FG-GAP,smart_Int_alpha_beta-p,smart_VWF_A,pfscan_VWF_A,prints_Integrin_alpha	-	no_errors	ITGA1	HGNC	ENSG00000213949	tier1	-	-	36	0	0.00	26	16	38.10						
PCDHGA11	0	genome.wustl.edu	37	5	140801354	140801354	+	Missense_Mutation	SNP	C	C	T			TCGA-LI-A67I-01A-31D-A307-09	TCGA-LI-A67I-10A-01D-A307-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	002585e4-d695-47b6-af2c-3429073bc0b4	3f1693c5-913e-4965-a931-af97a11388c6	5	140801354	140801354	C	T	SNP	PCDHGA11	ENST00000398587	human	ensembl	74_37	+1	known	missense	c.560	p.T187M	0.000	superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin	pfam_Cadherin,pfam_Cadherin_N,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin,prints_Cadherin	-	no_errors	PCDHGA11	HGNC	ENSG00000253873	tier1	-	-	39	0	0.00	36	14	28.00						
CFDP1	0	genome.wustl.edu	37	16	75327732	75327732	+	R	DEL	A	A	-			TCGA-LI-A67I-01A-31D-A307-09	TCGA-LI-A67I-10A-01D-A307-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	002585e4-d695-47b6-af2c-3429073bc0b4	3f1693c5-913e-4965-a931-af97a11388c6	16	75327732	75327732	A	-	DEL	CFDP1	ENST00000570103	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.940	-	-	-	no_errors	CFDP1	HGNC	ENSG00000153774	tier1			71	0	0.00	46	7	13.21						
SNORA30	0	genome.wustl.edu	37	16	30721932	30721932	+	R	SNP	T	T	G			TCGA-LI-A67I-01A-31D-A307-09	TCGA-LI-A67I-10A-01D-A307-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	002585e4-d695-47b6-af2c-3429073bc0b4	3f1693c5-913e-4965-a931-af97a11388c6	16	30721932	30721932	T	G	SNP	SNORA30	ENST00000384028	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.456	-	-	-	no_errors	SNORA30	HGNC	ENSG00000206755	tier1	-	-	105	0	0.00	68	19	21.84						
FBN1	0	genome.wustl.edu	37	15	48703246	48703277	+	Frame_Shift_Del	DEL	AGTCTTTGTCATATTTGTCTTCTAGTTGGTTA	AGTCTTTGTCATATTTGTCTTCTAGTTGGTTA	-			TCGA-LI-A67I-01A-31D-A307-09	TCGA-LI-A67I-10A-01D-A307-09	AGTCTTTGTCATATTTGTCTTCTAGTTGGTTA	AGTCTTTGTCATATTTGTCTTCTAGTTGGTTA					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	002585e4-d695-47b6-af2c-3429073bc0b4	3f1693c5-913e-4965-a931-af97a11388c6	15	48703246	48703277	AGTCTTTGTCATATTTGTCTTCTAGTTGGTTA	-	DEL	FBN1	ENST00000316623	human	ensembl	74_37	-1	known	frame_shift_del	c.8557_8526	p.N2843fs	1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:0.980:0.975:0.898:0.828	pirsf_FBN	pfam_EGF-like_Ca-bd_dom,pfam_EG-like_dom,pfam_TB_dom,superfamily_TB_dom,superfamily_Growth_fac_rcpt_N_dom,smart_EG-like_dom,smart_EGF-like_Ca-bd_dom,pirsf_FBN,pfscan_EG-like_dom	-	no_errors	FBN1	HGNC	ENSG00000166147	tier1														
PPP1R21	0	genome.wustl.edu	37	2	48734480	48734480	+	Nonsense_Mutation	SNP	C	C	T			TCGA-LI-A67I-01A-31D-A307-09	TCGA-LI-A67I-10A-01D-A307-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	002585e4-d695-47b6-af2c-3429073bc0b4	3f1693c5-913e-4965-a931-af97a11388c6	2	48734480	48734480	C	T	SNP	PPP1R21	ENST00000294952	human	ensembl	74_37	+1	known	nonsense	c.2041	p.Q681*	1.000	pfam_KLRAQ/TTKRSYEDQ_C	pfam_KLRAQ/TTKRSYEDQ_C,pfam_Unchr_KLRAQ/TTKRSYEDQ_N,superfamily_Ferritin-like_SF	-	no_errors	PPP1R21	HGNC	ENSG00000162869	tier1	-	-	208	0	0.00	149	61	29.05						
ALDH5A1	0	genome.wustl.edu	37	6	24502780	24502780	+	Silent	SNP	C	C	T			TCGA-LI-A67I-01A-31D-A307-09	TCGA-LI-A67I-10A-01D-A307-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	002585e4-d695-47b6-af2c-3429073bc0b4	3f1693c5-913e-4965-a931-af97a11388c6	6	24502780	24502780	C	T	SNP	ALDH5A1	ENST00000348925	human	ensembl	74_37	+1	known	silent	c.384	p.Y128	0.989	pfam_Aldehyde_DH_dom,superfamily_Ald_DH/histidinol_DH,tigrfam_Succ_semiAld_DH	pfam_Aldehyde_DH_dom,superfamily_Ald_DH/histidinol_DH,tigrfam_Succ_semiAld_DH	-	no_errors	ALDH5A1	HGNC	ENSG00000112294	tier1	-	-	189	0	0.00	74	105	58.66						
EIF5B	0	genome.wustl.edu	37	2	99977775	99977777	+	In_Frame_Del	DEL	TGA	TGA	-			TCGA-LI-A67I-01A-31D-A307-09	TCGA-LI-A67I-10A-01D-A307-09	TGA	TGA					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	002585e4-d695-47b6-af2c-3429073bc0b4	3f1693c5-913e-4965-a931-af97a11388c6	2	99977775	99977777	TGA	-	DEL	EIF5B	ENST00000289371	human	ensembl	74_37	+1	known	in_frame_del	c.411_413	p.D141in_frame_del	1.000:1.000:1.000	NULL	pfam_EF_GTP-bd_dom,pfam_TIF_IF2_dom3,pfam_Transl_elong_EFTu/EF1A_2,superfamily_P-loop_NTPase,superfamily_Transl_B-barrel,superfamily_TIF_IF2_dom3,prints_EF_GTP-bd_dom,tigrfam_Small_GTP-bd_dom	-	no_errors	EIF5B	HGNC	ENSG00000158417	tier1			33	0	0.00	18	4	18.18						
CRIP3	0	genome.wustl.edu	37	6	43275460	43275460	+	Missense_Mutation	SNP	C	C	T			TCGA-LI-A67I-01A-31D-A307-09	TCGA-LI-A67I-10A-01D-A307-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	002585e4-d695-47b6-af2c-3429073bc0b4	3f1693c5-913e-4965-a931-af97a11388c6	6	43275460	43275460	C	T	SNP	CRIP3	ENST00000274990	human	ensembl	74_37	-1	known	missense	c.218	p.G73D	1.000	NULL	pfam_Znf_LIM,smart_Znf_LIM,pfscan_Znf_LIM	-	no_errors	CRIP3	HGNC	ENSG00000146215	tier1	-	-	137	0	0.00	107	43	28.67						
TEKT4	0	genome.wustl.edu	37	2	95540568	95540568	+	Missense_Mutation	SNP	G	G	A			TCGA-LI-A67I-01A-31D-A307-09	TCGA-LI-A67I-10A-01D-A307-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	002585e4-d695-47b6-af2c-3429073bc0b4	3f1693c5-913e-4965-a931-af97a11388c6	2	95540568	95540568	G	A	SNP	TEKT4	ENST00000295201	human	ensembl	74_37	+1	known	missense	c.761	p.C254Y	0.001	pfam_Tektin	pfam_Tektin,prints_Tektin	-	no_errors	TEKT4	HGNC	ENSG00000163060	tier1	-	-	298	0	0.00	52	154	74.76						
SNORA30	0	genome.wustl.edu	37	16	30721934	30721935	+	R	INS	-	-	C			TCGA-LI-A67I-01A-31D-A307-09	TCGA-LI-A67I-10A-01D-A307-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	002585e4-d695-47b6-af2c-3429073bc0b4	3f1693c5-913e-4965-a931-af97a11388c6	16	30721934	30721935	-	C	INS	SNORA30	ENST00000384028	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.001:0.000	-	-	-	no_errors	SNORA30	HGNC	ENSG00000206755	tier1			106	0	0.00	73	18	19.78