Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	default_gene_name	gene_name_source	 ensembl_gene_id	tier	dbSNP	GMAF	n_ref_count	n_alt_count	normal_vaf	t_ref_count	t_alt_count	tumor_vaf	n_ref_count_val	n_alt_count_val	normal_vaf_val	t_ref_count_val	t_alt_count_val	tumor_vaf_val
ELP3	0	genome.wustl.edu	37	8	28017900	28017900	+	Missense_Mutation	SNP	T	T	C			TCGA-MJ-A68H-01A-11D-A307-09	TCGA-MJ-A68H-10A-01D-A307-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cbfa9116-45c9-422c-a976-4f0e021ec344	2a138f1b-62e6-42c6-b1a6-527769613304	8	28017900	28017900	T	C	SNP	ELP3	ENST00000256398	human	ensembl	74_37	+1	known	missense	c.1412	p.I471T	1.000	pfam_GT_dom,superfamily_Acyl_CoA_acyltransferase,pirsf_Hist_AcTrfase_ELP3,pfscan_GT_dom,tigrfam_Hist_AcTrfase_ELP3	pfam_rSAM,pfam_GT_dom,superfamily_Acyl_CoA_acyltransferase,smart_Elp3/MiaB/NifB,pirsf_Hist_AcTrfase_ELP3,pfscan_GT_dom,tigrfam_Hist_AcTrfase_ELP3	-	no_errors	ELP3	HGNC	ENSG00000134014	tier1	-	-	46	0	0.00	35	12	25.53	94	0	0.00	73	16	17.98
BRD2	0	genome.wustl.edu	37	6	32948413	32948413	+	Missense_Mutation	SNP	G	G	A			TCGA-MJ-A68H-01A-11D-A307-09	TCGA-MJ-A68H-10A-01D-A307-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cbfa9116-45c9-422c-a976-4f0e021ec344	2a138f1b-62e6-42c6-b1a6-527769613304	6	32948413	32948413	G	A	SNP	BRD2	ENST00000395289	human	ensembl	74_37	+1	known	missense	c.2429	p.S810N	1.000	NULL	pfam_Bromodomain,superfamily_Bromodomain,smart_Bromodomain,pfscan_Bromodomain,prints_Bromodomain	-	no_errors	BRD2	HGNC	ENSG00000204256	tier1	-	-	62	0	0.00	31	11	26.19	95	0	0.00	35	18	33.96
IGF2-AS	0	genome.wustl.edu	37	11	2167563	2167563	+	R	SNP	C	C	T			TCGA-MJ-A68H-01A-11D-A307-09	TCGA-MJ-A68H-10A-01D-A307-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cbfa9116-45c9-422c-a976-4f0e021ec344	2a138f1b-62e6-42c6-b1a6-527769613304	11	2167563	2167563	C	T	SNP	IGF2-AS	ENST00000381361	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	IGF2-AS	HGNC	ENSG00000099869	tier1	-	-	65	0	0.00	15	21	58.33	100	0	0.00	37	40	51.95
KIF1A	0	genome.wustl.edu	37	2	241662925	241662925	+	Missense_Mutation	SNP	G	G	A			TCGA-MJ-A68H-01A-11D-A307-09	TCGA-MJ-A68H-10A-01D-A307-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cbfa9116-45c9-422c-a976-4f0e021ec344	2a138f1b-62e6-42c6-b1a6-527769613304	2	241662925	241662925	G	A	SNP	KIF1A	ENST00000498729	human	ensembl	74_37	-1	known	missense	c.4369	p.R1457W	1.000	NULL	pfam_Kinesin_motor_dom,pfam_Kinesin-like,pfam_Pleckstrin_homology,pfam_KIF1B,pfam_FHA_dom,superfamily_P-loop_NTPase,superfamily_SMAD_FHA_domain,smart_Kinesin_motor_dom,smart_FHA_dom,smart_Pleckstrin_homology,pfscan_FHA_dom,pfscan_Pleckstrin_homology,pfscan_Kinesin_motor_dom,prints_Kinesin_motor_dom	-	no_errors	KIF1A	HGNC	ENSG00000130294	tier1	-	-	73	0	0.00	30	20	40.00	23	0	0.00	15	6	28.57
TGM3	0	genome.wustl.edu	37	20	2308810	2308810	+	Missense_Mutation	SNP	G	G	T			TCGA-MJ-A68H-01A-11D-A307-09	TCGA-MJ-A68H-10A-01D-A307-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cbfa9116-45c9-422c-a976-4f0e021ec344	2a138f1b-62e6-42c6-b1a6-527769613304	20	2308810	2308810	G	T	SNP	TGM3	ENST00000381458	human	ensembl	74_37	+1	known	missense	c.1132	p.G378C	0.998	NULL	pfam_Transglutaminase_C,pfam_Transglutaminase_N,pfam_Transglutaminase-like,superfamily_Ig_E-set,superfamily_Transglutaminase_C,smart_Transglutaminase-like	-	no_errors	TGM3	HGNC	ENSG00000125780	tier1	-	-	148	0	0.00	41	20	32.79	142	0	0.00	57	27	32.14
CEP128	0	genome.wustl.edu	37	14	81302669	81302669	+	Missense_Mutation	SNP	G	G	A			TCGA-MJ-A68H-01A-11D-A307-09	TCGA-MJ-A68H-10A-01D-A307-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cbfa9116-45c9-422c-a976-4f0e021ec344	2a138f1b-62e6-42c6-b1a6-527769613304	14	81302669	81302669	G	A	SNP	CEP128	ENST00000281129	human	ensembl	74_37	-1	known	missense	c.937	p.R313C	0.993	NULL	NULL	-	no_errors	CEP128	HGNC	ENSG00000100629	tier1	-	-	165	0	0.00	101	18	15.13	122	0	0.00	93	15	13.89
DSCAM	0	genome.wustl.edu	37	21	42080624	42080624	+	Silent	SNP	G	G	A			TCGA-MJ-A68H-01A-11D-A307-09	TCGA-MJ-A68H-10A-01D-A307-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cbfa9116-45c9-422c-a976-4f0e021ec344	2a138f1b-62e6-42c6-b1a6-527769613304	21	42080624	42080624	G	A	SNP	DSCAM	ENST00000400454	human	ensembl	74_37	-1	known	silent	c.117	p.T39	1.000	smart_Ig_sub2	pfam_Ig_I-set,pfam_Fibronectin_type3,pfam_Immunoglobulin,pfam_Ig_V-set,superfamily_Fibronectin_type3,smart_Ig_sub2,smart_Ig_sub,smart_Ig_V-set_subgr,smart_Fibronectin_type3,pfscan_Fibronectin_type3,pfscan_Ig-like_dom	-	no_errors	DSCAM	HGNC	ENSG00000171587	tier1	-	-	84	0	0.00	41	8	16.33	47	0	0.00	29	5	14.71
ZNF468	0	genome.wustl.edu	37	19	53344717	53344717	+	Missense_Mutation	SNP	C	C	A			TCGA-MJ-A68H-01A-11D-A307-09	TCGA-MJ-A68H-10A-01D-A307-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cbfa9116-45c9-422c-a976-4f0e021ec344	2a138f1b-62e6-42c6-b1a6-527769613304	19	53344717	53344717	C	A	SNP	ZNF468	ENST00000595646	human	ensembl	74_37	-1	known	missense	c.830	p.G277V	1.000	smart_Znf_C2H2-like,pfscan_Znf_C2H2	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF468	HGNC	ENSG00000204604	tier1	-	-	139	0	0.00	56	21	27.27	30	0	0.00	23	7	23.33
ABCC6	0	genome.wustl.edu	37	16	16244584	16244584	+	Silent	SNP	C	C	G			TCGA-MJ-A68H-01A-11D-A307-09	TCGA-MJ-A68H-10A-01D-A307-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cbfa9116-45c9-422c-a976-4f0e021ec344	2a138f1b-62e6-42c6-b1a6-527769613304	16	16244584	16244584	C	G	SNP	ABCC6	ENST00000205557	human	ensembl	74_37	-1	known	silent	c.4254	p.R1418	1.000	pfam_ABC_transporter-like,superfamily_P-loop_NTPase,smart_AAA+_ATPase,pfscan_ABC_transporter-like,tigrfam_Multidrug-R_assoc	pfam_ABC_transptr_TM_dom,pfam_ABC_transporter-like,superfamily_P-loop_NTPase,superfamily_ABC1_TM_dom,smart_AAA+_ATPase,pfscan_ABC_transporter-like,pfscan_ABC1_TM_dom,tigrfam_Multidrug-R_assoc	-	no_errors	ABCC6	HGNC	ENSG00000091262	tier1	-	-	50	0	0.00	15	17	53.12	34	0	0.00	23	15	39.47
SAA4	0	genome.wustl.edu	37	11	18257399	18257399	+	Silent	SNP	G	G	A			TCGA-MJ-A68H-01A-11D-A307-09	TCGA-MJ-A68H-10A-01D-A307-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cbfa9116-45c9-422c-a976-4f0e021ec344	2a138f1b-62e6-42c6-b1a6-527769613304	11	18257399	18257399	G	A	SNP	SAA4	ENST00000278222	human	ensembl	74_37	-1	known	silent	c.75	p.F25	0.001	pfam_Serum_amyloid_A,smart_Serum_amyloid_A,pirsf_Serum_amyloid_A,prints_Serum_amyloid_A	pfam_Serum_amyloid_A,superfamily_Actin_cross-linking,smart_Serum_amyloid_A,pirsf_Serum_amyloid_A,prints_Serum_amyloid_A	-	no_errors	SAA4	HGNC	ENSG00000148965	tier1	-	-	63	0	0.00	26	20	43.48	107	0	0.00	46	17	26.98
SOX7	0	genome.wustl.edu	37	8	10583914	10583914	+	Silent	SNP	G	G	A			TCGA-MJ-A68H-01A-11D-A307-09	TCGA-MJ-A68H-10A-01D-A307-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cbfa9116-45c9-422c-a976-4f0e021ec344	2a138f1b-62e6-42c6-b1a6-527769613304	8	10583914	10583914	G	A	SNP	SOX7	ENST00000553390	human	ensembl	74_37	-1	known	silent	c.657	p.P219	0.000	NULL	pfam_Sox_C_TAD,pfam_G_patch_dom,pfam_HMG_box_dom,superfamily_HMG_box_dom,smart_G_patch_dom,pfscan_G_patch_dom,pfscan_HMG_box_dom	-	no_errors	SOX7	HGNC	ENSG00000171056	tier1	-	-	38	0	0.00	17	6	26.09	14	0	0.00	10	9	47.37
GRID2IP	0	genome.wustl.edu	37	7	6579372	6579372	+	Nonsense_Mutation	SNP	G	G	T			TCGA-MJ-A68H-01A-11D-A307-09	TCGA-MJ-A68H-10A-01D-A307-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cbfa9116-45c9-422c-a976-4f0e021ec344	2a138f1b-62e6-42c6-b1a6-527769613304	7	6579372	6579372	G	T	SNP	GRID2IP	ENST00000457091	human	ensembl	74_37	-1	putative	nonsense	c.561	p.C187*	0.006	NULL	pfam_FH2_Formin,pfam_PDZ,superfamily_PDZ,smart_PDZ,smart_FH2_Formin,pfscan_PDZ	-	no_errors	GRID2IP	HGNC	ENSG00000215045	tier1	-	-	64	0	0.00	25	4	13.79	27	0	0.00	28	6	17.65
DJB3	0	genome.wustl.edu	37	2	234651912	234651912	+	R	SNP	A	A	T			TCGA-MJ-A68H-01A-11D-A307-09	TCGA-MJ-A68H-10A-01D-A307-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cbfa9116-45c9-422c-a976-4f0e021ec344	2a138f1b-62e6-42c6-b1a6-527769613304	2	234651912	234651912	A	T	SNP	DJB3	ENST00000449667	human	ensembl	74_37	-1	known	rna	NULL	NULL	1.000	-	-	-	no_errors	DJB3	HGNC	ENSG00000227802	tier1	-	-	151	0	0.00	55	16	22.22	34	0	0.00	25	10	28.57
A2MP1	0	genome.wustl.edu	37	12	9386053	9386053	+	R	SNP	C	C	T			TCGA-MJ-A68H-01A-11D-A307-09	TCGA-MJ-A68H-10A-01D-A307-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cbfa9116-45c9-422c-a976-4f0e021ec344	2a138f1b-62e6-42c6-b1a6-527769613304	12	9386053	9386053	C	T	SNP	A2MP1	ENST00000543404	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	A2MP1	HGNC	ENSG00000256069	tier1	-	-	67	0	0.00	25	8	24.24	77	0	0.00	33	10	23.26
C15orf26	0	genome.wustl.edu	37	15	81440868	81440868	+	Silent	SNP	G	G	A			TCGA-MJ-A68H-01A-11D-A307-09	TCGA-MJ-A68H-10A-01D-A307-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cbfa9116-45c9-422c-a976-4f0e021ec344	2a138f1b-62e6-42c6-b1a6-527769613304	15	81440868	81440868	G	A	SNP	C15orf26	ENST00000286732	human	ensembl	74_37	+1	known	silent	c.900	p.T300	0.000	NULL	NULL	-	no_errors	C15orf26	HGNC	ENSG00000156206	tier1	-	-	99	0	0.00	61	12	16.44	61	0	0.00	58	22	27.50
RG2	0	genome.wustl.edu	37	15	60720639	60720639	+	Missense_Mutation	SNP	T	T	C			TCGA-MJ-A68H-01A-11D-A307-09	TCGA-MJ-A68H-10A-01D-A307-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cbfa9116-45c9-422c-a976-4f0e021ec344	2a138f1b-62e6-42c6-b1a6-527769613304	15	60720639	60720639	T	C	SNP	RG2	ENST00000261520	human	ensembl	74_37	-1	known	missense	c.2809	p.T937A	0.000	NULL	pfam_RG2_C	-	no_errors	RG2	HGNC	ENSG00000128915	tier1	-	-	171	0	0.00	77	24	23.76	102	0	0.00	64	11	14.67
MARK2	0	genome.wustl.edu	37	11	63676504	63676504	+	Missense_Mutation	SNP	A	A	G			TCGA-MJ-A68H-01A-11D-A307-09	TCGA-MJ-A68H-10A-01D-A307-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cbfa9116-45c9-422c-a976-4f0e021ec344	2a138f1b-62e6-42c6-b1a6-527769613304	11	63676504	63676504	A	G	SNP	MARK2	ENST00000402010	human	ensembl	74_37	+1	known	missense	c.2162	p.N721S	1.000	superfamily_KA1/Ssp2_C	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_KA1_dom,superfamily_Kinase-like_dom,superfamily_KA1/Ssp2_C,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,smart_UBA/transl_elong_EF1B_N_euk,pfscan_UBA/transl_elong_EF1B_N_euk,pfscan_Prot_kinase_dom,prints_Ser-Thr/Tyr_kinase_cat_dom	-	no_errors	MARK2	HGNC	ENSG00000072518	tier1	-	-	62	0	0.00	34	11	24.44	21	0	0.00	10	7	41.18
ROBO2	0	genome.wustl.edu	37	3	77638020	77638020	+	Silent	SNP	G	G	A			TCGA-MJ-A68H-01A-11D-A307-09	TCGA-MJ-A68H-10A-01D-A307-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cbfa9116-45c9-422c-a976-4f0e021ec344	2a138f1b-62e6-42c6-b1a6-527769613304	3	77638020	77638020	G	A	SNP	ROBO2	ENST00000461745	human	ensembl	74_37	+1	known	silent	c.2619	p.L873	1.000	NULL	pfam_Ig_I-set,pfam_Immunoglobulin,pfam_Ig_V-set,pfam_Fibronectin_type3,superfamily_Fibronectin_type3,smart_Ig_sub,smart_Ig_sub2,smart_Ig_V-set_subgr,smart_Fibronectin_type3,pfscan_Fibronectin_type3,pfscan_Ig-like_dom	-	no_errors	ROBO2	HGNC	ENSG00000185008	tier1	-	-	204	0	0.00	168	25	12.95	149	0	0.00	122	26	17.57
PRPF4B	0	genome.wustl.edu	37	6	4062343	4062343	+	R	SNP	G	G	T			TCGA-MJ-A68H-01A-11D-A307-09	TCGA-MJ-A68H-10A-01D-A307-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cbfa9116-45c9-422c-a976-4f0e021ec344	2a138f1b-62e6-42c6-b1a6-527769613304	6	4062343	4062343	G	T	SNP	PRPF4B	ENST00000461612	human	ensembl	74_37	+1	known	rna	NULL	NULL	1.000	-	-	-	no_errors	PRPF4B	HGNC	ENSG00000112739	tier1	-	-	297	0	0.00	108	52	32.50	121	0	0.00	56	31	35.63
CLEC9A	0	genome.wustl.edu	37	12	10194076	10194076	+	R	SNP	C	C	T			TCGA-MJ-A68H-01A-11D-A307-09	TCGA-MJ-A68H-10A-01D-A307-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cbfa9116-45c9-422c-a976-4f0e021ec344	2a138f1b-62e6-42c6-b1a6-527769613304	12	10194076	10194076	C	T	SNP	CLEC9A	ENST00000544751	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.995	-	-	-	no_errors	CLEC9A	HGNC	ENSG00000197992	tier1	-	-	78	0	0.00	13	13	50.00	102	0	0.00	37	12	24.49
ASTN1	0	genome.wustl.edu	37	1	176998830	176998830	+	Missense_Mutation	SNP	C	C	T			TCGA-MJ-A68H-01A-11D-A307-09	TCGA-MJ-A68H-10A-01D-A307-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cbfa9116-45c9-422c-a976-4f0e021ec344	2a138f1b-62e6-42c6-b1a6-527769613304	1	176998830	176998830	C	T	SNP	ASTN1	ENST00000367654	human	ensembl	74_37	-1	known	missense	c.1060	p.E354K	1.000	NULL	superfamily_Fibronectin_type3,smart_EG-like_dom,smart_MACPF,pfscan_Fibronectin_type3	-	no_errors	ASTN1	HGNC	ENSG00000152092	tier1	-	-	138	0	0.00	60	23	27.71	109	0	0.00	55	22	28.57
CTNND1	0	genome.wustl.edu	37	11	57576833	57576833	+	Missense_Mutation	SNP	C	C	G			TCGA-MJ-A68H-01A-11D-A307-09	TCGA-MJ-A68H-10A-01D-A307-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cbfa9116-45c9-422c-a976-4f0e021ec344	2a138f1b-62e6-42c6-b1a6-527769613304	11	57576833	57576833	C	G	SNP	CTNND1	ENST00000399050	human	ensembl	74_37	+1	known	missense	c.2330	p.S777C	0.998	superfamily_ARM-type_fold	pfam_Armadillo,superfamily_ARM-type_fold,smart_Armadillo,pfscan_Armadillo	-	no_errors	CTNND1	HGNC	ENSG00000198561	tier1	-	-	113	0	0.00	41	22	34.92	149	0	0.00	76	26	25.49
TNFSF14	0	genome.wustl.edu	37	19	6669985	6669985	+	Silent	SNP	C	C	T			TCGA-MJ-A68H-01A-11D-A307-09	TCGA-MJ-A68H-10A-01D-A307-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cbfa9116-45c9-422c-a976-4f0e021ec344	2a138f1b-62e6-42c6-b1a6-527769613304	19	6669985	6669985	C	T	SNP	TNFSF14	ENST00000599359	human	ensembl	74_37	-1	known	silent	c.96	p.S32	0.296	NULL	pfam_TNF_dom,superfamily_Tumour_necrosis_fac-like_dom,smart_TNF_dom,pfscan_TNF_dom,prints_TNF	-	no_errors	TNFSF14	HGNC	ENSG00000125735	tier1	-	-	85	0	0.00	58	16	21.62	65	0	0.00	43	6	12.24
CCDC19	0	genome.wustl.edu	37	1	159860314	159860314	+	Silent	SNP	T	T	C			TCGA-MJ-A68H-01A-11D-A307-09	TCGA-MJ-A68H-10A-01D-A307-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cbfa9116-45c9-422c-a976-4f0e021ec344	2a138f1b-62e6-42c6-b1a6-527769613304	1	159860314	159860314	T	C	SNP	CCDC19	ENST00000368099	human	ensembl	74_37	-1	known	silent	c.228	p.P76	0.001	NULL	NULL	-	no_errors	CCDC19	HGNC	ENSG00000213085	tier1	-	-	140	0	0.00	45	12	21.05	91	0	0.00	48	14	22.58
SYNJ2	0	genome.wustl.edu	37	6	158515005	158515005	+	Missense_Mutation	SNP	G	G	A			TCGA-MJ-A68H-01A-11D-A307-09	TCGA-MJ-A68H-10A-01D-A307-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cbfa9116-45c9-422c-a976-4f0e021ec344	2a138f1b-62e6-42c6-b1a6-527769613304	6	158515005	158515005	G	A	SNP	SYNJ2	ENST00000367121	human	ensembl	74_37	+1	known	missense	c.3830	p.R1277K	1.000	NULL	pfam_Syja_N,pfam_DUF1866,pfam_Endo/exonuclease/phosphatase,superfamily_Endo/exonuclease/phosphatase,smart_IPPc,pfscan_RRM_dom,pfscan_Syja_N	-	no_errors	SYNJ2	HGNC	ENSG00000078269	tier1	-	-	207	1	0.48	65	30	31.58	111	1	0.89	44	21	32.31
GSTZ1	0	genome.wustl.edu	37	14	77795516	77795516	+	Silent	SNP	C	C	T			TCGA-MJ-A68H-01A-11D-A307-09	TCGA-MJ-A68H-10A-01D-A307-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cbfa9116-45c9-422c-a976-4f0e021ec344	2a138f1b-62e6-42c6-b1a6-527769613304	14	77795516	77795516	C	T	SNP	GSTZ1	ENST00000216465	human	ensembl	74_37	+1	known	silent	c.393	p.A131	1.000	pfam_GST_C,superfamily_Glutathione-S-Trfase_C-like,tigrfam_Mal_ac_isom	pfam_Glutathione_S-Trfase_N,pfam_GST_C,superfamily_Glutathione-S-Trfase_C-like,superfamily_Thioredoxin-like_fold,tigrfam_Mal_ac_isom	-	no_errors	GSTZ1	HGNC	ENSG00000100577	tier1	-	-	87	0	0.00	52	13	20.00	99	0	0.00	61	7	10.29
KMT2A	0	genome.wustl.edu	37	11	118375819	118375819	+	Missense_Mutation	SNP	C	C	T			TCGA-MJ-A68H-01A-11D-A307-09	TCGA-MJ-A68H-10A-01D-A307-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cbfa9116-45c9-422c-a976-4f0e021ec344	2a138f1b-62e6-42c6-b1a6-527769613304	11	118375819	118375819	C	T	SNP	KMT2A	ENST00000389506	human	ensembl	74_37	+1	known	missense	c.9203	p.P3068L	1.000	pirsf_MeTrfase_trithorax	pfam_SET_dom,pfam_FYrich_C,pfam_Znf_PHD-finger,pfam_FYrich_N,pfam_Znf_CXXC,superfamily_Znf_FYVE_PHD,superfamily_Bromodomain,smart_Znf_PHD,smart_Bromodomain,smart_FYrich_N,smart_FYrich_C,smart_SET_dom,smart_Post-SET_dom,pirsf_MeTrfase_trithorax,pfscan_SET_dom,pfscan_Post-SET_dom,pfscan_Znf_PHD-finger,pfscan_Znf_CXXC,pfscan_Bromodomain	-	no_errors	KMT2A	HGNC	ENSG00000118058	tier1	-	-	68	0	0.00	22	9	29.03	123	1	0.81	56	20	25.97
CSGALCT1	0	genome.wustl.edu	37	8	19297416	19297416	+	Missense_Mutation	SNP	C	C	G			TCGA-MJ-A68H-01A-11D-A307-09	TCGA-MJ-A68H-10A-01D-A307-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cbfa9116-45c9-422c-a976-4f0e021ec344	2a138f1b-62e6-42c6-b1a6-527769613304	8	19297416	19297416	C	G	SNP	CSGALCT1	ENST00000311540	human	ensembl	74_37	-1	known	missense	c.878	p.R293T	1.000	pfam_Chond_Galc	pfam_Chond_Galc	-	no_errors	CSGALCT1	HGNC	ENSG00000147408	tier1	-	-	83	0	0.00	50	15	23.08	93	0	0.00	81	21	20.59
OR51Q1	0	genome.wustl.edu	37	11	5444200	5444200	+	Missense_Mutation	SNP	T	T	A			TCGA-MJ-A68H-01A-11D-A307-09	TCGA-MJ-A68H-10A-01D-A307-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cbfa9116-45c9-422c-a976-4f0e021ec344	2a138f1b-62e6-42c6-b1a6-527769613304	11	5444200	5444200	T	A	SNP	OR51Q1	ENST00000300778	human	ensembl	74_37	+1	known	missense	c.770	p.M257K	0.878	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR51Q1	HGNC	ENSG00000167360	tier1	-	-	64	0	0.00	19	14	42.42	84	0	0.00	65	21	24.42
PNPLA7	0	genome.wustl.edu	37	9	140437933	140437933	+	Nonsense_Mutation	SNP	T	T	A			TCGA-MJ-A68H-01A-11D-A307-09	TCGA-MJ-A68H-10A-01D-A307-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cbfa9116-45c9-422c-a976-4f0e021ec344	2a138f1b-62e6-42c6-b1a6-527769613304	9	140437933	140437933	T	A	SNP	PNPLA7	ENST00000406427	human	ensembl	74_37	-1	known	nonsense	c.457	p.K153*	1.000	NULL	pfam_cNMP-bd_dom,pfam_Patatin/PLipase_A2-rel,superfamily_Acyl_Trfase/lysoPLipase,superfamily_cNMP-bd-like,smart_cNMP-bd_dom,pfscan_cNMP-bd_dom	-	no_errors	PNPLA7	HGNC	ENSG00000130653	tier1	-	-	93	0	0.00	12	11	47.83	67	0	0.00	14	20	58.82
IQCG	0	genome.wustl.edu	37	3	197665423	197665423	+	Missense_Mutation	SNP	C	C	G			TCGA-MJ-A68H-01A-11D-A307-09	TCGA-MJ-A68H-10A-01D-A307-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cbfa9116-45c9-422c-a976-4f0e021ec344	2a138f1b-62e6-42c6-b1a6-527769613304	3	197665423	197665423	C	G	SNP	IQCG	ENST00000265239	human	ensembl	74_37	-1	known	missense	c.511	p.D171H	0.956	NULL	pfam_IQ_motif_EF-hand-BS,superfamily_P-loop_NTPase,pfscan_IQ_motif_EF-hand-BS	-	no_errors	IQCG	HGNC	ENSG00000114473	tier1	-	-	112	0	0.00	42	15	26.32	127	0	0.00	51	28	35.44
PARN	0	genome.wustl.edu	37	16	14711476	14711476	+	Missense_Mutation	SNP	C	C	T			TCGA-MJ-A68H-01A-11D-A307-09	TCGA-MJ-A68H-10A-01D-A307-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cbfa9116-45c9-422c-a976-4f0e021ec344	2a138f1b-62e6-42c6-b1a6-527769613304	16	14711476	14711476	C	T	SNP	PARN	ENST00000437198	human	ensembl	74_37	-1	known	missense	c.359	p.G120E	1.000	pfam_RNase_CAF1,superfamily_RNaseH-like_dom	pfam_RNase_CAF1,pfam_PolyA-riboNase_R_binding,pfam_R3H_ss-bd,superfamily_RNaseH-like_dom,pfscan_R3H_ss-bd	-	no_errors	PARN	HGNC	ENSG00000140694	tier1	-	-	161	0	0.00	54	47	46.53	109	0	0.00	50	40	44.44
DH9	0	genome.wustl.edu	37	17	11583113	11583113	+	Silent	SNP	C	C	T			TCGA-MJ-A68H-01A-11D-A307-09	TCGA-MJ-A68H-10A-01D-A307-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cbfa9116-45c9-422c-a976-4f0e021ec344	2a138f1b-62e6-42c6-b1a6-527769613304	17	11583113	11583113	C	T	SNP	DH9	ENST00000262442	human	ensembl	74_37	+1	known	silent	c.3393	p.S1131	0.001	NULL	pfam_Dynein_heavy_dom,pfam_Dynein_heavy_dom-1,pfam_Dynein_heavy_dom-2,pfam_ATPase_dyneun-rel_AAA,superfamily_P-loop_NTPase,smart_AAA+_ATPase	-	no_errors	DH9	HGNC	ENSG00000007174	tier1	-	-	123	0	0.00	46	16	25.81	112	0	0.00	53	34	39.08
IFI35	0	genome.wustl.edu	37	17	41164274	41164274	+	Missense_Mutation	SNP	G	G	A			TCGA-MJ-A68H-01A-11D-A307-09	TCGA-MJ-A68H-10A-01D-A307-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cbfa9116-45c9-422c-a976-4f0e021ec344	2a138f1b-62e6-42c6-b1a6-527769613304	17	41164274	41164274	G	A	SNP	IFI35	ENST00000438323	human	ensembl	74_37	+1	known	missense	c.100	p.G34R	0.000	pfam_Nmi/IFP35_N	pfam_Nmi/IFP35_dom,pfam_Nmi/IFP35_N	-	no_errors	IFI35	HGNC	ENSG00000068079	tier1	-	-	36	0	0.00	19	4	17.39	98	0	0.00	57	25	30.49
CNTRL	0	genome.wustl.edu	37	9	123921164	123921164	+	Missense_Mutation	SNP	T	T	C			TCGA-MJ-A68H-01A-11D-A307-09	TCGA-MJ-A68H-10A-01D-A307-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cbfa9116-45c9-422c-a976-4f0e021ec344	2a138f1b-62e6-42c6-b1a6-527769613304	9	123921164	123921164	T	C	SNP	CNTRL	ENST00000238341	human	ensembl	74_37	+1	known	missense	c.4796	p.L1599S	0.997	NULL	pfam_Leu-rich_rpt,superfamily_Prefoldin,superfamily_tR-bd_arm,smart_Leu-rich_rpt_typical-subtyp	-	no_errors	CNTRL	HGNC	ENSG00000119397	tier1	-	-	91	0	0.00	24	15	38.46	100	0	0.00	27	18	40.00
BEND4	0	genome.wustl.edu	37	4	42145445	42145445	+	Missense_Mutation	SNP	C	C	A			TCGA-MJ-A68H-01A-11D-A307-09	TCGA-MJ-A68H-10A-01D-A307-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cbfa9116-45c9-422c-a976-4f0e021ec344	2a138f1b-62e6-42c6-b1a6-527769613304	4	42145445	42145445	C	A	SNP	BEND4	ENST00000502486	human	ensembl	74_37	-1	known	missense	c.1054	p.V352L	1.000	NULL	pfam_BEN_domain	-	no_errors	BEND4	HGNC	ENSG00000188848	tier1	-	-	84	0	0.00	42	32	43.24	125	0	0.00	92	50	35.21
COG8	0	genome.wustl.edu	37	16	69368559	69368559	+	Silent	SNP	G	G	A			TCGA-MJ-A68H-01A-11D-A307-09	TCGA-MJ-A68H-10A-01D-A307-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cbfa9116-45c9-422c-a976-4f0e021ec344	2a138f1b-62e6-42c6-b1a6-527769613304	16	69368559	69368559	G	A	SNP	COG8	ENST00000306875	human	ensembl	74_37	-1	known	silent	c.1278	p.P426	0.882	pirsf_COG8_Metazoal_Plant	pfam_COG8,superfamily_Cullin_repeat-like_dom,pirsf_COG8_Metazoal_Plant	-	no_errors	COG8	HGNC	ENSG00000213380	tier1	-	-	44	0	0.00	15	59	79.73	56	0	0.00	35	128	78.53
TROAP	0	genome.wustl.edu	37	12	49719940	49719940	+	Missense_Mutation	SNP	C	C	T			TCGA-MJ-A68H-01A-11D-A307-09	TCGA-MJ-A68H-10A-01D-A307-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cbfa9116-45c9-422c-a976-4f0e021ec344	2a138f1b-62e6-42c6-b1a6-527769613304	12	49719940	49719940	C	T	SNP	TROAP	ENST00000257909	human	ensembl	74_37	+1	known	missense	c.715	p.R239W	0.965	NULL	NULL	-	no_errors	TROAP	HGNC	ENSG00000135451	tier1	-	-	95	0	0.00	28	14	33.33	115	0	0.00	69	27	28.12
FARSB	0	genome.wustl.edu	37	2	223493573	223493573	+	Missense_Mutation	SNP	T	T	C			TCGA-MJ-A68H-01A-11D-A307-09	TCGA-MJ-A68H-10A-01D-A307-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cbfa9116-45c9-422c-a976-4f0e021ec344	2a138f1b-62e6-42c6-b1a6-527769613304	2	223493573	223493573	T	C	SNP	FARSB	ENST00000281828	human	ensembl	74_37	-1	known	missense	c.883	p.K295E	0.998	tigrfam_Phe-tR-synth_IIc_bsu_arc	pfam_B3/B4_tR-bd,pfam_tR_synthase_B5-dom,superfamily_D-bd_dom_put,superfamily_Phe-tR_synthase_B3/B4,smart_B3/B4_tR-bd,smart_tR_synthase_B5-dom,tigrfam_Phe-tR-synth_IIc_bsu_arc	-	no_errors	FARSB	HGNC	ENSG00000116120	tier1	-	-	99	0	0.00	33	17	34.00	108	0	0.00	41	18	30.51
ZMYND8	0	genome.wustl.edu	37	20	45867527	45867527	+	Silent	SNP	T	T	C			TCGA-MJ-A68H-01A-11D-A307-09	TCGA-MJ-A68H-10A-01D-A307-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cbfa9116-45c9-422c-a976-4f0e021ec344	2a138f1b-62e6-42c6-b1a6-527769613304	20	45867527	45867527	T	C	SNP	ZMYND8	ENST00000536340	human	ensembl	74_37	-1	known	silent	c.2661	p.R887	1.000	NULL	pfam_DUF3544,pfam_Bromodomain,pfam_PWWP_dom,pfam_Znf_PHD-finger,pfam_Znf_MYND,superfamily_Bromodomain,superfamily_Znf_FYVE_PHD,smart_Znf_PHD,smart_Bromodomain,smart_PWWP_dom,pfscan_PWWP_dom,pfscan_Znf_MYND,pfscan_Znf_PHD-finger,pfscan_Bromodomain	-	no_errors	ZMYND8	HGNC	ENSG00000101040	tier1	-	-	147	0	0.00	35	22	38.60	61	0	0.00	44	12	21.43
ADAMTS6	0	genome.wustl.edu	37	5	64466447	64466447	+	Missense_Mutation	SNP	C	C	T			TCGA-MJ-A68H-01A-11D-A307-09	TCGA-MJ-A68H-10A-01D-A307-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cbfa9116-45c9-422c-a976-4f0e021ec344	2a138f1b-62e6-42c6-b1a6-527769613304	5	64466447	64466447	C	T	SNP	ADAMTS6	ENST00000381055	human	ensembl	74_37	-1	known	missense	c.3241	p.E1081K	1.000	pfscan_PLAC	pfam_ADAM_spacer1,pfam_Peptidase_M12B_N,pfam_Peptidase_M12B,pfam_Thrombospondin_1_rpt,pfam_PLAC,superfamily_Thrombospondin_1_rpt,smart_Thrombospondin_1_rpt,prints_Peptidase_M12B_ADAM-TS,pfscan_PLAC,pfscan_Thrombospondin_1_rpt,pfscan_Peptidase_M12B	-	no_errors	ADAMTS6	HGNC	ENSG00000049192	tier1	-	-	77	0	0.00	46	16	25.81	101	0	0.00	60	16	21.05
CPB1	0	genome.wustl.edu	37	3	148577804	148577804	+	R	SNP	G	G	A			TCGA-MJ-A68H-01A-11D-A307-09	TCGA-MJ-A68H-10A-01D-A307-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cbfa9116-45c9-422c-a976-4f0e021ec344	2a138f1b-62e6-42c6-b1a6-527769613304	3	148577804	148577804	G	A	SNP	CPB1	ENST00000476847	human	ensembl	74_37	+1	putative	rna	NULL	NULL	0.000	-	-	-	no_errors	CPB1	HGNC	ENSG00000153002	tier1	-	-	167	1	0.60	30	43	58.90	55	0	0.00	19	20	51.28
ATP5J2	0	genome.wustl.edu	37	7	99063734	99063734	+	Missense_Mutation	SNP	C	C	G			TCGA-MJ-A68H-01A-11D-A307-09	TCGA-MJ-A68H-10A-01D-A307-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cbfa9116-45c9-422c-a976-4f0e021ec344	2a138f1b-62e6-42c6-b1a6-527769613304	7	99063734	99063734	C	G	SNP	ATP5J2	ENST00000292475	human	ensembl	74_37	-1	known	missense	c.31	p.V11L	0.000	NULL	pfam_F1F0-ATPsyn_F_prd	-	no_errors	ATP5J2	HGNC	ENSG00000241468	tier1	-	-	76	0	0.00	27	18	40.00	68	0	0.00	31	14	31.11
USH2A	0	genome.wustl.edu	37	1	216062283	216062284	+	Frame_Shift_Ins	INS	-	-	AT			TCGA-MJ-A68H-01A-11D-A307-09	TCGA-MJ-A68H-10A-01D-A307-09	-	-	-	AT	-	-	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cbfa9116-45c9-422c-a976-4f0e021ec344	2a138f1b-62e6-42c6-b1a6-527769613304	1	216062283	216062284	-	AT	INS	USH2A	ENST00000366943	human	ensembl	74_37	-1	known	frame_shift_ins	c.7708_7707	p.L2569fs	1.000:1.000	pfam_Fibronectin_type3,superfamily_Fibronectin_type3,smart_Fibronectin_type3,pfscan_Fibronectin_type3	pfam_Fibronectin_type3,pfam_EGF_laminin,pfam_Laminin_G,superfamily_ConA-like_lec_gl_sf,superfamily_Fibronectin_type3,smart_LamG-like,smart_Laminin_N,smart_EGF_laminin,smart_Fibronectin_type3,smart_Laminin_G,pfscan_EGF_laminin,pfscan_Fibronectin_type3,pfscan_Laminin_G,pfscan_Laminin_N	-	no_errors	USH2A	HGNC	ENSG00000042781	tier1			50	0	0.00	16	7	30.43	109	0	0.00	59	18	23.38
ZDHHC11B	0	genome.wustl.edu	37	5	711036	711037	+	R	INS	-	-	GA			TCGA-MJ-A68H-01A-11D-A307-09	TCGA-MJ-A68H-10A-01D-A307-09	-	-	-	GA	-	-	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cbfa9116-45c9-422c-a976-4f0e021ec344	2a138f1b-62e6-42c6-b1a6-527769613304	5	711036	711037	-	GA	INS	ZDHHC11B	ENST00000522356	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000:0.006	-	-	-	no_errors	ZDHHC11B	HGNC	ENSG00000206077	tier1			53	0	0.00	18	3	14.29	27	0	0.00	19	5	20.83
MAPK1	0	genome.wustl.edu	37	22	22161991	22161993	+	In_Frame_Del	DEL	GTC	GTC	-			TCGA-MJ-A68H-01A-11D-A307-09	TCGA-MJ-A68H-10A-01D-A307-09	GTC	GTC	GTC	-	GTC	GTC	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cbfa9116-45c9-422c-a976-4f0e021ec344	2a138f1b-62e6-42c6-b1a6-527769613304	22	22161991	22161993	GTC	-	DEL	MAPK1	ENST00000215832	human	ensembl	74_37	-1	known	in_frame_del	c.264_262	p.D88in_frame_del	0.999:1.000:1.000	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom,prints_MAPK_ERK1/2,prints_MAPK_ERK3/4	-	no_errors	MAPK1	HGNC	ENSG00000100030	tier1			136	0	0.00	67	20	22.99	130	0	0.00	86	19	18.10
GGT6	0	genome.wustl.edu	37	17	4462705	4462705	+	Silent	SNP	G	G	A			TCGA-MJ-A68H-01A-11D-A307-09	TCGA-MJ-A68H-10A-01D-A307-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cbfa9116-45c9-422c-a976-4f0e021ec344	2a138f1b-62e6-42c6-b1a6-527769613304	17	4462705	4462705	G	A	SNP	GGT6	ENST00000574154	human	ensembl	74_37	-1	known	silent	c.372	p.N124	0.681	pfam_GGT_peptidase,prints_GGT_peptidase	pfam_GGT_peptidase,prints_GGT_peptidase	-	no_errors	GGT6	HGNC	ENSG00000167741	tier1	-	-	130	0	0.00	20	24	54.55	35	0	0.00	4	5	55.56
IKZF1	0	genome.wustl.edu	37	7	50467870	50467870	+	Missense_Mutation	SNP	G	G	A			TCGA-MJ-A68H-01A-11D-A307-09	TCGA-MJ-A68H-10A-01D-A307-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cbfa9116-45c9-422c-a976-4f0e021ec344	2a138f1b-62e6-42c6-b1a6-527769613304	7	50467870	50467870	G	A	SNP	IKZF1	ENST00000331340	human	ensembl	74_37	+1	known	missense	c.1105	p.A369T	1.000	NULL	pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2	-	no_errors	IKZF1	HGNC	ENSG00000185811	tier1	-	-	49	0	0.00	13	18	58.06	7	0	0.00	1	3	75.00
LRRC8A	0	genome.wustl.edu	37	9	131670725	131670725	+	Silent	SNP	C	C	T			TCGA-MJ-A68H-01A-11D-A307-09	TCGA-MJ-A68H-10A-01D-A307-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cbfa9116-45c9-422c-a976-4f0e021ec344	2a138f1b-62e6-42c6-b1a6-527769613304	9	131670725	131670725	C	T	SNP	LRRC8A	ENST00000259324	human	ensembl	74_37	+1	known	silent	c.1282	p.L428	1.000	NULL	pfam_LRR_protein-8_N,pfam_Leu-rich_rpt,smart_Leu-rich_rpt_typical-subtyp	-	no_errors	LRRC8A	HGNC	ENSG00000136802	tier1	-	-	55	0	0.00	10	8	44.44	31	0	0.00	9	5	35.71
PLEKHG6	0	genome.wustl.edu	37	12	6437022	6437022	+	Missense_Mutation	SNP	G	G	A			TCGA-MJ-A68H-01A-11D-A307-09	TCGA-MJ-A68H-10A-01D-A307-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cbfa9116-45c9-422c-a976-4f0e021ec344	2a138f1b-62e6-42c6-b1a6-527769613304	12	6437022	6437022	G	A	SNP	PLEKHG6	ENST00000011684	human	ensembl	74_37	+1	known	missense	c.2273	p.R758Q	0.000	NULL	pfam_DH-domain,superfamily_DH-domain,smart_DH-domain,smart_Pleckstrin_homology,pfscan_Pleckstrin_homology,pfscan_DH-domain	-	no_errors	PLEKHG6	HGNC	ENSG00000008323	tier1	-	-	82	0	0.00	12	21	63.64	9	0	0.00	3	2	40.00
RABL6	0	genome.wustl.edu	37	9	139733681	139733681	+	Missense_Mutation	SNP	A	A	C			TCGA-MJ-A68H-01A-11D-A307-09	TCGA-MJ-A68H-10A-01D-A307-09	A	A	A	C	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cbfa9116-45c9-422c-a976-4f0e021ec344	2a138f1b-62e6-42c6-b1a6-527769613304	9	139733681	139733681	A	C	SNP	RABL6	ENST00000371663	human	ensembl	74_37	+1	known	missense	c.1504	p.I502L	0.178	NULL	pfam_Small_GTPase,pfam_MIRO-like,pfam_Small_GTPase_ARF/SAR,superfamily_P-loop_NTPase,smart_Small_GTPase_Rab_type,prints_Small_GTPase	-	no_errors	RABL6	HGNC	ENSG00000196642	tier1	-	-	107	0	0.00	46	18	27.69	30	0	0.00	3	5	62.50
SLC35A5	0	genome.wustl.edu	37	3	112300027	112300027	+	Missense_Mutation	SNP	C	C	T			TCGA-MJ-A68H-01A-11D-A307-09	TCGA-MJ-A68H-10A-01D-A307-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cbfa9116-45c9-422c-a976-4f0e021ec344	2a138f1b-62e6-42c6-b1a6-527769613304	3	112300027	112300027	C	T	SNP	SLC35A5	ENST00000492406	human	ensembl	74_37	+1	known	missense	c.1063	p.P355S	1.000	pfam_Nuc_sug_transpt,pfam_UAA,pirsf_UDP/CMP-sugar_transptr,tigrfam_UDPgal_transpt	pfam_Nuc_sug_transpt,pfam_UAA,pfam_DMT,pfam_Tpt_PEP_trans_dom,pirsf_UDP/CMP-sugar_transptr,tigrfam_UDPgal_transpt	-	no_errors	SLC35A5	HGNC	ENSG00000138459	tier1	-	-	160	1	0.62	61	16	20.78	116	2	1.69	58	21	26.58
HAS1	0	genome.wustl.edu	37	19	52217143	52217143	+	Missense_Mutation	SNP	G	G	A			TCGA-MJ-A68H-01A-11D-A307-09	TCGA-MJ-A68H-10A-01D-A307-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cbfa9116-45c9-422c-a976-4f0e021ec344	2a138f1b-62e6-42c6-b1a6-527769613304	19	52217143	52217143	G	A	SNP	HAS1	ENST00000601714	human	ensembl	74_37	-1	known	missense	c.1295	p.A432V	0.872	NULL	pfam_Chitin_synth_fng,pfam_Glyco_trans_2	-	no_errors	HAS1	HGNC	ENSG00000105509	tier1	-	-	77	0	0.00	30	11	26.83	22	0	0.00	6	1	14.29
MAP1LC3A	0	genome.wustl.edu	37	20	33147737	33147737	+	R	DEL	C	C	-			TCGA-MJ-A68H-01A-11D-A307-09	TCGA-MJ-A68H-10A-01D-A307-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cbfa9116-45c9-422c-a976-4f0e021ec344	2a138f1b-62e6-42c6-b1a6-527769613304	20	33147737	33147737	C	-	DEL	MAP1LC3A	ENST00000476428	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.018	-	-	-	no_errors	MAP1LC3A	HGNC	ENSG00000101460	tier1			38	0	0.00	22	3	12.00	11	0	0.00	9	0	0.00
ZNF765	0	genome.wustl.edu	37	19	53911520	53911520	+	Missense_Mutation	SNP	T	T	G			TCGA-MJ-A68H-01A-11D-A307-09	TCGA-MJ-A68H-10A-01D-A307-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cbfa9116-45c9-422c-a976-4f0e021ec344	2a138f1b-62e6-42c6-b1a6-527769613304	19	53911520	53911520	T	G	SNP	ZNF765	ENST00000396408	human	ensembl	74_37	+1	known	missense	c.712	p.L238V	0.561	pfscan_Znf_C2H2	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF765	HGNC	ENSG00000196417	tier1	-	-	145	0	0.00	52	38	42.22	23	0	0.00	9	1	10.00
PI4KAP2	0	genome.wustl.edu	37	22	21846328	21846328	+	R	SNP	G	G	T			TCGA-MJ-A68H-01A-11D-A307-09	TCGA-MJ-A68H-10A-01D-A307-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cbfa9116-45c9-422c-a976-4f0e021ec344	2a138f1b-62e6-42c6-b1a6-527769613304	22	21846328	21846328	G	T	SNP	PI4KAP2	ENST00000450651	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.990	-	-	-	no_errors	PI4KAP2	HGNC	ENSG00000183506	tier1	-	-	55	0	0.00	24	4	14.29	0	0	0.00	0	0	0.00
TRPM2	0	genome.wustl.edu	37	21	45844781	45844781	+	Missense_Mutation	SNP	G	G	A			TCGA-MJ-A68H-01A-11D-A307-09	TCGA-MJ-A68H-10A-01D-A307-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cbfa9116-45c9-422c-a976-4f0e021ec344	2a138f1b-62e6-42c6-b1a6-527769613304	21	45844781	45844781	G	A	SNP	TRPM2	ENST00000300482	human	ensembl	74_37	+1	known	missense	c.3596	p.R1199Q	0.784	NULL	pfam_Ion_trans_dom,superfamily_NUDIX_hydrolase_dom-like	-	no_errors	TRPM2	HGNC	ENSG00000142185	tier1	-	-	65	0	0.00	24	7	22.58	1	0	0.00	1	1	50.00