Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	default_gene_name	gene_name_source	 ensembl_gene_id	tier	dbSNP	GMAF	n_ref_count	n_alt_count	normal_vaf	t_ref_count	t_alt_count	tumor_vaf	n_ref_count_val	n_alt_count_val	normal_vaf_val	t_ref_count_val	t_alt_count_val	tumor_vaf_val
ZFAND1	0	genome.wustl.edu	37	8	82626245	82626245	+	Nonsense_Mutation	SNP	G	G	A			TCGA-PC-A5DN-01A-12D-A27P-09	TCGA-PC-A5DN-10A-01D-A27P-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	60581c5a-e89b-4e0e-bb80-20a3b14f4638	680014f0-e224-4d25-9929-02de0f4b2f44	8	82626245	82626245	G	A	SNP	ZFAND1	ENST00000220669	human	ensembl	74_37	-1	known	nonsense	c.388	p.R130*	1.000	NULL	pfam_Znf_AN1,smart_Znf_AN1,pfscan_Znf_AN1	-	no_errors	ZFAND1	HGNC	ENSG00000104231	tier1	-	-	58	0	0.00	30	21	41.18	74	0	0.00	70	29	29.29
ZNF77	0	genome.wustl.edu	37	19	2933833	2933833	+	Missense_Mutation	SNP	G	G	A			TCGA-PC-A5DN-01A-12D-A27P-09	TCGA-PC-A5DN-10A-01D-A27P-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	60581c5a-e89b-4e0e-bb80-20a3b14f4638	680014f0-e224-4d25-9929-02de0f4b2f44	19	2933833	2933833	G	A	SNP	ZNF77	ENST00000314531	human	ensembl	74_37	-1	known	missense	c.1292	p.T431I	0.988	pfscan_Znf_C2H2	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF77	HGNC	ENSG00000175691	tier1	-	-	63	0	0.00	36	13	26.53	66	1	1.49	57	28	32.94
SLCO4C1	0	genome.wustl.edu	37	5	101631937	101631937	+	Missense_Mutation	SNP	C	C	A			TCGA-PC-A5DN-01A-12D-A27P-09	TCGA-PC-A5DN-10A-01D-A27P-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	60581c5a-e89b-4e0e-bb80-20a3b14f4638	680014f0-e224-4d25-9929-02de0f4b2f44	5	101631937	101631937	C	A	SNP	SLCO4C1	ENST00000310954	human	ensembl	74_37	-1	known	missense	c.30	p.L10F	1.000	NULL	pfam_OA_transporter,pfam_MFS,pfam_Kazal_dom,superfamily_MFS_dom_general_subst_transpt,pfscan_MFS_dom,tigrfam_OA_transporter	-	no_errors	SLCO4C1	HGNC	ENSG00000173930	tier1	-	-	70	0	0.00	39	23	37.10	58	0	0.00	48	29	37.66
PRG4	0	genome.wustl.edu	37	1	186277602	186277602	+	Silent	SNP	C	C	T			TCGA-PC-A5DN-01A-12D-A27P-09	TCGA-PC-A5DN-10A-01D-A27P-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	60581c5a-e89b-4e0e-bb80-20a3b14f4638	680014f0-e224-4d25-9929-02de0f4b2f44	1	186277602	186277602	C	T	SNP	PRG4	ENST00000445192	human	ensembl	74_37	+1	known	silent	c.2751	p.D917	0.002	NULL	pfam_Somatomedin_B_dom,pfam_Hemopexin-like_repeat,superfamily_Hemopexin-like_dom,smart_Somatomedin_B_dom,smart_Hemopexin-like_repeat,prints_Somatomedin_B_chordata,pfscan_Somatomedin_B_dom	-	no_errors	PRG4	HGNC	ENSG00000116690	tier1	-	-	54	0	0.00	26	20	43.48	81	1	1.22	59	69	53.91
OR2V2	0	genome.wustl.edu	37	5	180582465	180582465	+	Missense_Mutation	SNP	G	G	T			TCGA-PC-A5DN-01A-12D-A27P-09	TCGA-PC-A5DN-10A-01D-A27P-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	60581c5a-e89b-4e0e-bb80-20a3b14f4638	680014f0-e224-4d25-9929-02de0f4b2f44	5	180582465	180582465	G	T	SNP	OR2V2	ENST00000328275	human	ensembl	74_37	+1	known	missense	c.523	p.V175L	0.071	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR2V2	HGNC	ENSG00000182613	tier1	rs147476494	GMAF=0.0005	141	0	0.00	71	30	29.70	118	0	0.00	64	32	33.33
RYR1	0	genome.wustl.edu	37	19	38954158	38954158	+	Silent	SNP	C	C	T			TCGA-PC-A5DN-01A-12D-A27P-09	TCGA-PC-A5DN-10A-01D-A27P-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	60581c5a-e89b-4e0e-bb80-20a3b14f4638	680014f0-e224-4d25-9929-02de0f4b2f44	19	38954158	38954158	C	T	SNP	RYR1	ENST00000359596	human	ensembl	74_37	+1	known	silent	c.2673	p.T891	0.999	pfam_Ryanodine_rcpt,prints_Ryan_recept	pfam_Ca-rel_channel,pfam_Ryanodine_rcpt,pfam_Ryanrecept_TM4-6,pfam_SPRY_rcpt,pfam_Ins145_P3_rcpt,pfam_MIR_motif,pfam_RIH_assoc-dom,pfam_Ion_trans_dom,superfamily_MIR_motif,superfamily_ConA-like_lec_gl_sf,superfamily_MG_RAP_rcpt_1,smart_MIR_motif,smart_SPla/RYanodine_receptor_subgr,prints_Ryan_recept,pfscan_B30.2/SPRY,pfscan_MIR_motif	-	no_errors	RYR1	HGNC	ENSG00000196218	tier1	-	-	87	0	0.00	47	20	29.85	7	0	0.00	10	3	23.08
MUC2	0	genome.wustl.edu	37	11	1085815	1085815	+	Silent	SNP	G	G	T			TCGA-PC-A5DN-01A-12D-A27P-09	TCGA-PC-A5DN-10A-01D-A27P-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	60581c5a-e89b-4e0e-bb80-20a3b14f4638	680014f0-e224-4d25-9929-02de0f4b2f44	11	1085815	1085815	G	T	SNP	MUC2	ENST00000441003	human	ensembl	74_37	+1	known	silent	c.2736	p.T912	0.025	pfam_VWF_type-D,smart_VWF_type-D	pfam_VWF_type-D,pfam_Unchr_dom_Cys-rich,pfam_TIL_dom,superfamily_TIL_dom,superfamily_Prot_inh_PMP,smart_VWF_type-D,smart_Unchr_dom_Cys-rich,smart_VWC_out,smart_VWF_C,smart_Cys_knot_C,pfscan_Cys_knot_C,pfscan_VWF_C	-	no_errors	MUC2	HGNC	ENSG00000198788	tier1	-	-	53	0	0.00	32	20	38.46	27	0	0.00	21	10	32.26
UNC13C	0	genome.wustl.edu	37	15	54307904	54307904	+	Nonsense_Mutation	SNP	T	T	G			TCGA-PC-A5DN-01A-12D-A27P-09	TCGA-PC-A5DN-10A-01D-A27P-09	T	T	T	G	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	60581c5a-e89b-4e0e-bb80-20a3b14f4638	680014f0-e224-4d25-9929-02de0f4b2f44	15	54307904	54307904	T	G	SNP	UNC13C	ENST00000260323	human	ensembl	74_37	+1	known	nonsense	c.2804	p.L935*	0.900	NULL	pfam_Munc13_subgr_dom-2,pfam_Ca-dep_secretion_activator,pfam_C2_dom,pfam_Prot_Kinase_C-like_PE/DAG-bd,superfamily_C2_dom,smart_Prot_Kinase_C-like_PE/DAG-bd,smart_C2_dom,pfscan_C2_dom,pfscan_Prot_Kinase_C-like_PE/DAG-bd,prints_C2_dom	-	no_errors	UNC13C	HGNC	ENSG00000137766	tier1	-	-	59	0	0.00	34	6	15.00	88	0	0.00	64	28	30.43
CES1	0	genome.wustl.edu	37	16	55844440	55844440	+	Missense_Mutation	SNP	C	C	T			TCGA-PC-A5DN-01A-12D-A27P-09	TCGA-PC-A5DN-10A-01D-A27P-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	60581c5a-e89b-4e0e-bb80-20a3b14f4638	680014f0-e224-4d25-9929-02de0f4b2f44	16	55844440	55844440	C	T	SNP	CES1	ENST00000360526	human	ensembl	74_37	-1	known	missense	c.1307	p.R436Q	0.044	pfam_CarbesteraseB	pfam_CarbesteraseB,pfam_AB_hydrolase_3	-	no_errors	CES1	HGNC	ENSG00000198848	tier1	rs145088728	-	238	0	0.00	134	42	23.86	111	0	0.00	80	29	26.61
DOCK2	0	genome.wustl.edu	37	5	169435513	169435513	+	Missense_Mutation	SNP	T	T	A			TCGA-PC-A5DN-01A-12D-A27P-09	TCGA-PC-A5DN-10A-01D-A27P-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	60581c5a-e89b-4e0e-bb80-20a3b14f4638	680014f0-e224-4d25-9929-02de0f4b2f44	5	169435513	169435513	T	A	SNP	DOCK2	ENST00000256935	human	ensembl	74_37	+1	known	missense	c.3085	p.Y1029N	1.000	superfamily_ARM-type_fold,superfamily_Ferritin-like_SF	pfam_DOCK_C,pfam_SH3_2,superfamily_SH3_domain,superfamily_Cyt_c-like_dom,superfamily_ARM-type_fold,superfamily_Ferritin-like_SF,smart_SH3_domain,pfscan_SH3_domain	-	no_errors	DOCK2	HGNC	ENSG00000134516	tier1	-	-	64	0	0.00	45	14	23.73	50	0	0.00	47	25	34.72
CCDC60	0	genome.wustl.edu	37	12	119968845	119968845	+	Missense_Mutation	SNP	C	C	A			TCGA-PC-A5DN-01A-12D-A27P-09	TCGA-PC-A5DN-10A-01D-A27P-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	60581c5a-e89b-4e0e-bb80-20a3b14f4638	680014f0-e224-4d25-9929-02de0f4b2f44	12	119968845	119968845	C	A	SNP	CCDC60	ENST00000327554	human	ensembl	74_37	+1	known	missense	c.1528	p.P510T	0.999	NULL	NULL	-	no_errors	CCDC60	HGNC	ENSG00000183273	tier1	-	-	76	0	0.00	49	160	76.19	99	0	0.00	85	331	79.57
ACSM2A	0	genome.wustl.edu	37	16	20482862	20482862	+	Missense_Mutation	SNP	A	A	G			TCGA-PC-A5DN-01A-12D-A27P-09	TCGA-PC-A5DN-10A-01D-A27P-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	60581c5a-e89b-4e0e-bb80-20a3b14f4638	680014f0-e224-4d25-9929-02de0f4b2f44	16	20482862	20482862	A	G	SNP	ACSM2A	ENST00000219054	human	ensembl	74_37	+1	known	missense	c.745	p.T249A	0.138	pfam_AMP-dep_Synth/Lig	pfam_AMP-dep_Synth/Lig	-	no_errors	ACSM2A	HGNC	ENSG00000183747	tier1	-	-	120	0	0.00	85	11	11.46	44	0	0.00	42	11	20.75
ABCA7	0	genome.wustl.edu	37	19	1063802	1063802	+	Missense_Mutation	SNP	T	T	A			TCGA-PC-A5DN-01A-12D-A27P-09	TCGA-PC-A5DN-10A-01D-A27P-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	60581c5a-e89b-4e0e-bb80-20a3b14f4638	680014f0-e224-4d25-9929-02de0f4b2f44	19	1063802	1063802	T	A	SNP	ABCA7	ENST00000263094	human	ensembl	74_37	+1	known	missense	c.5891	p.L1964H	1.000	superfamily_P-loop_NTPase,smart_AAA+_ATPase,pfscan_ABC_transporter-like	pfam_ABC_transporter-like,superfamily_P-loop_NTPase,superfamily_GroES-like,smart_AAA+_ATPase,pfscan_ABC_transporter-like	-	no_errors	ABCA7	HGNC	ENSG00000064687	tier1	-	-	147	0	0.00	101	28	21.71	19	0	0.00	19	4	17.39
KLK13	0	genome.wustl.edu	37	19	51563252	51563252	+	Missense_Mutation	SNP	C	C	T			TCGA-PC-A5DN-01A-12D-A27P-09	TCGA-PC-A5DN-10A-01D-A27P-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	60581c5a-e89b-4e0e-bb80-20a3b14f4638	680014f0-e224-4d25-9929-02de0f4b2f44	19	51563252	51563252	C	T	SNP	KLK13	ENST00000595793	human	ensembl	74_37	-1	known	missense	c.338	p.R113Q	0.925	pfam_Peptidase_S1,pfam_Peptidase_S1A_nudel,superfamily_Trypsin-like_Pept_dom,smart_Peptidase_S1,pfscan_Peptidase_S1	pfam_Peptidase_S1,pfam_Peptidase_S1A_nudel,superfamily_Trypsin-like_Pept_dom,smart_Peptidase_S1,pfscan_Peptidase_S1,prints_Peptidase_S1A	-	no_errors	KLK13	HGNC	ENSG00000167759	tier1	-	-	50	0	0.00	22	5	18.52	53	0	0.00	47	8	14.55
THSD7A	0	genome.wustl.edu	37	7	11457208	11457208	+	Missense_Mutation	SNP	C	C	T			TCGA-PC-A5DN-01A-12D-A27P-09	TCGA-PC-A5DN-10A-01D-A27P-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	60581c5a-e89b-4e0e-bb80-20a3b14f4638	680014f0-e224-4d25-9929-02de0f4b2f44	7	11457208	11457208	C	T	SNP	THSD7A	ENST00000423059	human	ensembl	74_37	-1	known	missense	c.3406	p.G1136S	1.000	pfam_Thrombospondin_1_rpt,superfamily_Thrombospondin_1_rpt,smart_Thrombospondin_1_rpt,pfscan_Thrombospondin_1_rpt	pfam_Thrombospondin_1_rpt,superfamily_Thrombospondin_1_rpt,smart_Thrombospondin_1_rpt,pfscan_Thrombospondin_1_rpt	-	no_errors	THSD7A	HGNC	ENSG00000005108	tier1	-	-	31	0	0.00	28	6	17.65	62	0	0.00	29	10	25.64
LOC730811	0	genome.wustl.edu	37	2	2328430	2328430	+	R	SNP	C	C	T			TCGA-PC-A5DN-01A-12D-A27P-09	TCGA-PC-A5DN-10A-01D-A27P-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	60581c5a-e89b-4e0e-bb80-20a3b14f4638	680014f0-e224-4d25-9929-02de0f4b2f44	2	2328430	2328430	C	T	SNP	LOC730811	ENST00000422175	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.004	-	-	-	no_errors	AC009232.2	Clone_based_vega_gene	ENSG00000225619	tier1	-	-	60	0	0.00	33	24	42.11	19	0	0.00	14	5	26.32
MAGI3	0	genome.wustl.edu	37	1	114184712	114184712	+	Missense_Mutation	SNP	A	A	T			TCGA-PC-A5DN-01A-12D-A27P-09	TCGA-PC-A5DN-10A-01D-A27P-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	60581c5a-e89b-4e0e-bb80-20a3b14f4638	680014f0-e224-4d25-9929-02de0f4b2f44	1	114184712	114184712	A	T	SNP	MAGI3	ENST00000369611	human	ensembl	74_37	+1	known	missense	c.1540	p.I514F	0.997	NULL	pfam_PDZ,pfam_WW_dom,pfam_GK/Ca_channel_bsu,superfamily_PDZ,superfamily_P-loop_NTPase,superfamily_WW_dom,smart_PDZ,smart_GK/Ca_channel_bsu,smart_WW_dom,pfscan_PDZ,pfscan_WW_dom,pfscan_Guanylate_kin-like	-	no_errors	MAGI3	HGNC	ENSG00000081026	tier1	-	-	151	0	0.00	92	32	25.81	78	0	0.00	42	26	38.24
KLK3	0	genome.wustl.edu	37	19	51361292	51361292	+	Missense_Mutation	SNP	G	G	A			TCGA-PC-A5DN-01A-12D-A27P-09	TCGA-PC-A5DN-10A-01D-A27P-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	60581c5a-e89b-4e0e-bb80-20a3b14f4638	680014f0-e224-4d25-9929-02de0f4b2f44	19	51361292	51361292	G	A	SNP	KLK3	ENST00000326003	human	ensembl	74_37	+1	known	missense	c.214	p.V72M	0.000	pfam_Peptidase_S1,superfamily_Trypsin-like_Pept_dom,smart_Peptidase_S1,pfscan_Peptidase_S1	pfam_Peptidase_S1,superfamily_Trypsin-like_Pept_dom,smart_Peptidase_S1,pfscan_Peptidase_S1,prints_Peptidase_S1A	-	no_errors	KLK3	HGNC	ENSG00000142515	tier1	rs148892721	-	50	0	0.00	20	11	35.48	37	0	0.00	35	9	20.45
CTSL	0	genome.wustl.edu	37	9	90343553	90343553	+	Silent	SNP	G	G	A			TCGA-PC-A5DN-01A-12D-A27P-09	TCGA-PC-A5DN-10A-01D-A27P-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	60581c5a-e89b-4e0e-bb80-20a3b14f4638	680014f0-e224-4d25-9929-02de0f4b2f44	9	90343553	90343553	G	A	SNP	CTSL	ENST00000340342	human	ensembl	74_37	+1	known	silent	c.450	p.Q150	1.000	pfam_Peptidase_C1A_C,smart_Peptidase_C1A_C	pfam_Peptidase_C1A_C,pfam_Prot_inhib_I29,smart_Prot_inhib_I29,smart_Peptidase_C1A_C,prints_Peptidase_C1A_C	-	no_errors	CTSL	HGNC	ENSG00000135047	tier1	-	-	109	0	0.00	59	44	42.72	59	0	0.00	39	12	23.53
CDA	0	genome.wustl.edu	37	1	20915751	20915751	+	Silent	SNP	C	C	T			TCGA-PC-A5DN-01A-12D-A27P-09	TCGA-PC-A5DN-10A-01D-A27P-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	60581c5a-e89b-4e0e-bb80-20a3b14f4638	680014f0-e224-4d25-9929-02de0f4b2f44	1	20915751	20915751	C	T	SNP	CDA	ENST00000375071	human	ensembl	74_37	+1	known	silent	c.129	p.L43	1.000	pfam_CMP_dCMP_Zn-bd,pfam_Cyd/dCyd_deaminase_Zn-bd,superfamily_Cytidine_deaminase-like,tigrfam_Cyt_deam_tetra	pfam_CMP_dCMP_Zn-bd,pfam_Cyd/dCyd_deaminase_Zn-bd,superfamily_Cytidine_deaminase-like,tigrfam_Cyt_deam_tetra	-	no_errors	CDA	HGNC	ENSG00000158825	tier1	rs149177918	-	61	0	0.00	21	17	44.74	43	0	0.00	17	23	57.50
TMEM168	0	genome.wustl.edu	37	7	112415372	112415372	+	Missense_Mutation	SNP	G	G	A			TCGA-PC-A5DN-01A-12D-A27P-09	TCGA-PC-A5DN-10A-01D-A27P-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	60581c5a-e89b-4e0e-bb80-20a3b14f4638	680014f0-e224-4d25-9929-02de0f4b2f44	7	112415372	112415372	G	A	SNP	TMEM168	ENST00000312814	human	ensembl	74_37	-1	known	missense	c.1130	p.P377L	1.000	NULL	superfamily_ConA-like_lec_gl_sf	-	no_errors	TMEM168	HGNC	ENSG00000146802	tier1	-	-	43	0	0.00	17	7	29.17	54	0	0.00	60	16	20.78
OR5M10	0	genome.wustl.edu	37	11	56344717	56344717	+	Missense_Mutation	SNP	G	G	C			TCGA-PC-A5DN-01A-12D-A27P-09	TCGA-PC-A5DN-10A-01D-A27P-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	60581c5a-e89b-4e0e-bb80-20a3b14f4638	680014f0-e224-4d25-9929-02de0f4b2f44	11	56344717	56344717	G	C	SNP	OR5M10	ENST00000526812	human	ensembl	74_37	-1	known	missense	c.481	p.L161V	0.000	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR5M10	HGNC	ENSG00000254834	tier1	-	-	53	0	0.00	42	4	8.70	79	0	0.00	56	7	11.11
ATRX	0	genome.wustl.edu	37	X	76875866	76875866	+	Missense_Mutation	SNP	C	C	G			TCGA-PC-A5DN-01A-12D-A27P-09	TCGA-PC-A5DN-10A-01D-A27P-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	60581c5a-e89b-4e0e-bb80-20a3b14f4638	680014f0-e224-4d25-9929-02de0f4b2f44	X	76875866	76875866	C	G	SNP	ATRX	ENST00000373344	human	ensembl	74_37	-1	known	missense	c.5269	p.E1757Q	1.000	pfam_SNF2_N,superfamily_P-loop_NTPase,smart_Helicase_ATP-bd,pfscan_Helicase_ATP-bd	pfam_SNF2_N,pfam_Helicase_C,superfamily_P-loop_NTPase,superfamily_Znf_FYVE_PHD,smart_Helicase_ATP-bd,smart_Helicase_C,pfscan_Helicase_ATP-bd,pfscan_Helicase_C	-	no_errors	ATRX	HGNC	ENSG00000085224	tier1	-	-	153	0	0.00	58	27	31.40	45	0	0.00	58	28	32.56
TRPC1	0	genome.wustl.edu	37	3	142511714	142511714	+	Missense_Mutation	SNP	C	C	G			TCGA-PC-A5DN-01A-12D-A27P-09	TCGA-PC-A5DN-10A-01D-A27P-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	60581c5a-e89b-4e0e-bb80-20a3b14f4638	680014f0-e224-4d25-9929-02de0f4b2f44	3	142511714	142511714	C	G	SNP	TRPC1	ENST00000476941	human	ensembl	74_37	+1	known	missense	c.1486	p.L496V	0.996	pfam_Ion_trans_dom,tigrfam_TRP_channel	pfam_TRP_dom,pfam_Ion_trans_dom,superfamily_Ankyrin_rpt-contain_dom,smart_Ankyrin_rpt,prints_TRPC1_channel,prints_TRPC_channel,tigrfam_TRP_channel	-	no_errors	TRPC1	HGNC	ENSG00000144935	tier1	-	-	107	0	0.00	74	31	29.52	60	0	0.00	42	14	25.00
WDFY3	0	genome.wustl.edu	37	4	85742335	85742335	+	Missense_Mutation	SNP	T	T	C			TCGA-PC-A5DN-01A-12D-A27P-09	TCGA-PC-A5DN-10A-01D-A27P-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	60581c5a-e89b-4e0e-bb80-20a3b14f4638	680014f0-e224-4d25-9929-02de0f4b2f44	4	85742335	85742335	T	C	SNP	WDFY3	ENST00000295888	human	ensembl	74_37	-1	known	missense	c.1493	p.D498G	1.000	superfamily_ARM-type_fold	pfam_BEACH_dom,pfam_Znf_FYVE,pfam_WD40_repeat,superfamily_BEACH_dom,superfamily_WD40_repeat_dom,superfamily_Znf_FYVE_PHD,superfamily_ConA-like_lec_gl_sf,superfamily_Cyclin-like,superfamily_ARM-type_fold,smart_WD40_repeat,smart_Znf_FYVE,pfscan_BEACH_dom,pfscan_Znf_FYVE-rel,pfscan_WD40_repeat,pfscan_WD40_repeat_dom	-	no_errors	WDFY3	HGNC	ENSG00000163625	tier1	-	-	57	0	0.00	31	13	29.55	100	0	0.00	78	24	23.53
CCR1	0	genome.wustl.edu	37	3	46245242	46245242	+	Missense_Mutation	SNP	G	G	C			TCGA-PC-A5DN-01A-12D-A27P-09	TCGA-PC-A5DN-10A-01D-A27P-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	60581c5a-e89b-4e0e-bb80-20a3b14f4638	680014f0-e224-4d25-9929-02de0f4b2f44	3	46245242	46245242	G	C	SNP	CCR1	ENST00000296140	human	ensembl	74_37	-1	known	missense	c.563	p.P188R	1.000	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfam_7TM_GPCR_serpentine_rcpt_Srx,pfscan_GPCR_Rhodpsn_7TM,prints_Chemokine_CCR1,prints_Chemokine_CCR5	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfam_7TM_GPCR_serpentine_rcpt_Srx,pfscan_GPCR_Rhodpsn_7TM,prints_Chemokine_CCR1,prints_GPCR_Rhodpsn,prints_Chemokine_rcpt,prints_Chemokine_CCR5,prints_NPY_rcpt,prints_ATII_rcpt	-	no_errors	CCR1	HGNC	ENSG00000163823	tier1	-	-	53	0	0.00	33	8	19.51	89	0	0.00	67	28	29.47
ZKSCAN8	0	genome.wustl.edu	37	6	28121130	28121130	+	Missense_Mutation	SNP	G	G	T			TCGA-PC-A5DN-01A-12D-A27P-09	TCGA-PC-A5DN-10A-01D-A27P-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	60581c5a-e89b-4e0e-bb80-20a3b14f4638	680014f0-e224-4d25-9929-02de0f4b2f44	6	28121130	28121130	G	T	SNP	ZKSCAN8	ENST00000330236	human	ensembl	74_37	+1	known	missense	c.1072	p.A358S	1.000	pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2	pfam_Znf_C2H2,pfam_Tscrpt_reg_SCAN,pfam_Krueppel-associated_box,superfamily_Retrov_capsid_C,superfamily_Krueppel-associated_box,smart_Tscrpt_reg_SCAN,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box,pfscan_Tscrpt_reg_SCAN	-	no_errors	ZKSCAN8	HGNC	ENSG00000198315	tier1	-	-	64	0	0.00	35	10	22.22	119	0	0.00	91	37	28.68
LRRTM4	0	genome.wustl.edu	37	2	77745759	77745759	+	Silent	SNP	G	G	A			TCGA-PC-A5DN-01A-12D-A27P-09	TCGA-PC-A5DN-10A-01D-A27P-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	60581c5a-e89b-4e0e-bb80-20a3b14f4638	680014f0-e224-4d25-9929-02de0f4b2f44	2	77745759	77745759	G	A	SNP	LRRTM4	ENST00000409911	human	ensembl	74_37	-1	known	silent	c.1239	p.G413	0.977	NULL	pfam_Leu-rich_rpt,smart_Leu-rich_rpt_typical-subtyp	-	no_errors	LRRTM4	HGNC	ENSG00000176204	tier1	-	-	52	0	0.00	45	12	21.05	101	1	0.98	65	26	28.57
RORC	0	genome.wustl.edu	37	1	151785408	151785408	+	R	SNP	C	C	T			TCGA-PC-A5DN-01A-12D-A27P-09	TCGA-PC-A5DN-10A-01D-A27P-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	60581c5a-e89b-4e0e-bb80-20a3b14f4638	680014f0-e224-4d25-9929-02de0f4b2f44	1	151785408	151785408	C	T	SNP	RORC	ENST00000480719	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.979	-	-	-	no_errors	RORC	HGNC	ENSG00000143365	tier1	-	-	45	0	0.00	28	18	39.13	62	0	0.00	65	20	23.53
CNR1	0	genome.wustl.edu	37	6	88854824	88854824	+	Missense_Mutation	SNP	G	G	C			TCGA-PC-A5DN-01A-12D-A27P-09	TCGA-PC-A5DN-10A-01D-A27P-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	60581c5a-e89b-4e0e-bb80-20a3b14f4638	680014f0-e224-4d25-9929-02de0f4b2f44	6	88854824	88854824	G	C	SNP	CNR1	ENST00000369499	human	ensembl	74_37	-1	known	missense	c.170	p.P57R	1.000	pirsf_Canbinoid_rcpt_1,prints_Canbinoid_rcpt_1	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfam_7TM_GPCR_serpentine_rcpt_Srx,pirsf_Canbinoid_rcpt_1,pfscan_GPCR_Rhodpsn_7TM,prints_Canbinoid_rcpt_1,prints_Cnbnoid_rcpt,prints_GPCR_Rhodpsn	-	no_errors	CNR1	HGNC	ENSG00000118432	tier1	-	-	114	0	0.00	46	25	35.21	83	0	0.00	56	29	33.72
ROCK1	0	genome.wustl.edu	37	18	18566975	18566975	+	Missense_Mutation	SNP	T	T	C			TCGA-PC-A5DN-01A-12D-A27P-09	TCGA-PC-A5DN-10A-01D-A27P-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	60581c5a-e89b-4e0e-bb80-20a3b14f4638	680014f0-e224-4d25-9929-02de0f4b2f44	18	18566975	18566975	T	C	SNP	ROCK1	ENST00000399799	human	ensembl	74_37	-1	known	missense	c.2240	p.D747G	1.000	pirsf_Rho-assoc_coiled-coil_kin	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Rho-bd_dom,pfam_HR1_rho-bd,pfam_Pleckstrin_homology,pfam_Pkinase_C,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,smart_AGC-kinase_C,smart_Pleckstrin_homology,smart_Prot_Kinase_C-like_PE/DAG-bd,pirsf_Rho-assoc_coiled-coil_kin,pfscan_Pleckstrin_homology,pfscan_Prot_Kinase_C-like_PE/DAG-bd,pfscan_Prot_kinase_dom	-	no_errors	ROCK1	HGNC	ENSG00000067900	tier1	-	-	86	0	0.00	39	17	30.36	78	0	0.00	68	26	27.66
SNORD116-2	0	genome.wustl.edu	37	15	25299398	25299398	+	R	SNP	G	G	C			TCGA-PC-A5DN-01A-12D-A27P-09	TCGA-PC-A5DN-10A-01D-A27P-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	60581c5a-e89b-4e0e-bb80-20a3b14f4638	680014f0-e224-4d25-9929-02de0f4b2f44	15	25299398	25299398	G	C	SNP	SNORD116-2	ENST00000384274	human	ensembl	74_37	+1	known	rna	NULL	NULL	1.000	-	-	-	no_errors	SNORD116-2	HGNC	ENSG00000207001	tier1	-	-	142	0	0.00	67	18	21.18	24	0	0.00	23	11	32.35
SH3RF2	0	genome.wustl.edu	37	5	145428732	145428732	+	Missense_Mutation	SNP	G	G	T			TCGA-PC-A5DN-01A-12D-A27P-09	TCGA-PC-A5DN-10A-01D-A27P-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	60581c5a-e89b-4e0e-bb80-20a3b14f4638	680014f0-e224-4d25-9929-02de0f4b2f44	5	145428732	145428732	G	T	SNP	SH3RF2	ENST00000359120	human	ensembl	74_37	+1	known	missense	c.1246	p.G416C	1.000	pfam_SH3_2,pfam_SH3_domain,superfamily_SH3_domain,smart_SH3_domain,pfscan_SH3_domain	pfam_SH3_2,pfam_SH3_domain,pfam_Znf_C3HC4_RING-type,superfamily_SH3_domain,smart_Znf_RING,smart_SH3_domain,pfscan_SH3_domain,pfscan_Znf_RING,prints_SH3_domain	-	no_errors	SH3RF2	HGNC	ENSG00000156463	tier1	-	-	73	0	0.00	46	28	37.84	35	0	0.00	31	7	18.42
HCK	0	genome.wustl.edu	37	20	30662496	30662496	+	Missense_Mutation	SNP	G	G	A			TCGA-PC-A5DN-01A-12D-A27P-09	TCGA-PC-A5DN-10A-01D-A27P-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	60581c5a-e89b-4e0e-bb80-20a3b14f4638	680014f0-e224-4d25-9929-02de0f4b2f44	20	30662496	30662496	G	A	SNP	HCK	ENST00000375852	human	ensembl	74_37	+1	known	missense	c.400	p.A134T	1.000	pfam_SH3_2,smart_SH3_domain,pfscan_SH3_domain,prints_SH3_domain	pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_kinase_dom,pfam_SH2,pfam_SH3_domain,pfam_SH3_2,superfamily_Kinase-like_dom,superfamily_SH3_domain,smart_SH3_domain,smart_SH2,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_SH2,pfscan_SH3_domain,pfscan_Prot_kinase_dom,prints_Ser-Thr/Tyr_kinase_cat_dom,prints_SH2,prints_SH3_domain	-	no_errors	HCK	HGNC	ENSG00000101336	tier1	-	-	77	0	0.00	45	15	25.00	83	0	0.00	42	22	34.38
CNTD2	0	genome.wustl.edu	37	19	40729532	40729532	+	Silent	SNP	G	G	A			TCGA-PC-A5DN-01A-12D-A27P-09	TCGA-PC-A5DN-10A-01D-A27P-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	60581c5a-e89b-4e0e-bb80-20a3b14f4638	680014f0-e224-4d25-9929-02de0f4b2f44	19	40729532	40729532	G	A	SNP	CNTD2	ENST00000221818	human	ensembl	74_37	-1	known	silent	c.441	p.N147	0.000	NULL	pfam_Cyclin_N,superfamily_Cyclin-like	-	no_errors	CNTD2	HGNC	ENSG00000105219	tier1	-	-	49	0	0.00	14	11	44.00	97	0	0.00	43	24	35.82
ASPN	0	genome.wustl.edu	37	9	95236911	95236911	+	Missense_Mutation	SNP	T	T	G			TCGA-PC-A5DN-01A-12D-A27P-09	TCGA-PC-A5DN-10A-01D-A27P-09	T	T	T	G	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	60581c5a-e89b-4e0e-bb80-20a3b14f4638	680014f0-e224-4d25-9929-02de0f4b2f44	9	95236911	95236911	T	G	SNP	ASPN	ENST00000375544	human	ensembl	74_37	-1	known	missense	c.269	p.D90A	1.000	pfam_LRR-contain_N,smart_LRR-contain_N,pirsf_SLRP_I_decor/aspor/byglycan	pfam_Leu-rich_rpt,pfam_LRR-contain_N,smart_LRR-contain_N,smart_Leu-rich_rpt_typical-subtyp,pirsf_SLRP_I_decor/aspor/byglycan	-	no_errors	ASPN	HGNC	ENSG00000106819	tier1	-	-	36	0	0.00	23	13	36.11	77	0	0.00	53	22	29.33
PTH2R	0	genome.wustl.edu	37	2	209302606	209302606	+	Silent	SNP	G	G	A			TCGA-PC-A5DN-01A-12D-A27P-09	TCGA-PC-A5DN-10A-01D-A27P-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	60581c5a-e89b-4e0e-bb80-20a3b14f4638	680014f0-e224-4d25-9929-02de0f4b2f44	2	209302606	209302606	G	A	SNP	PTH2R	ENST00000272847	human	ensembl	74_37	+1	known	silent	c.411	p.K137	1.000	NULL	pfam_GPCR_2_secretin-like,pfam_GPCR_2_extracellular_dom,smart_GPCR_2_extracellular_dom,pfscan_GPCR_2_extracellular_dom,pfscan_GPCR_2-like,prints_GPCR_2_secretin-like	-	no_errors	PTH2R	HGNC	ENSG00000144407	tier1	-	-	40	0	0.00	12	7	36.84	62	0	0.00	33	12	26.67
SUSD1	0	genome.wustl.edu	37	9	114919796	114919797	+	Frame_Shift_Ins	INS	-	-	GAGG			TCGA-PC-A5DN-01A-12D-A27P-09	TCGA-PC-A5DN-10A-01D-A27P-09	-	-	-	GAGG	-	-	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	60581c5a-e89b-4e0e-bb80-20a3b14f4638	680014f0-e224-4d25-9929-02de0f4b2f44	9	114919796	114919797	-	GAGG	INS	SUSD1	ENST00000374264	human	ensembl	74_37	-1	known	frame_shift_ins	c.201_200	p.R68fs	1.000:1.000	smart_EG-like_dom,pfscan_EG-like_dom	pfam_EGF-like_Ca-bd_dom,pfam_Sushi_SCR_CCP,superfamily_Sushi_SCR_CCP,superfamily_Fibronectin_type3,smart_EG-like_dom,smart_EGF-like_Ca-bd_dom,smart_Sushi_SCR_CCP,pfscan_EG-like_dom,pfscan_Sushi_SCR_CCP	-	no_errors	SUSD1	HGNC	ENSG00000106868	tier1			80	0	0.00	42	13	23.64	97	0	0.00	84	23	21.50
AGTR1	0	genome.wustl.edu	37	3	148459421	148459422	+	Frame_Shift_Del	DEL	AT	AT	-			TCGA-PC-A5DN-01A-12D-A27P-09	TCGA-PC-A5DN-10A-01D-A27P-09	AT	AT	AT	-	AT	AT	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	60581c5a-e89b-4e0e-bb80-20a3b14f4638	680014f0-e224-4d25-9929-02de0f4b2f44	3	148459421	148459422	AT	-	DEL	AGTR1	ENST00000349243	human	ensembl	74_37	+1	known	frame_shift_del	c.599_600	p.I201fs	1.000:0.996	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_ATII_rcpt,prints_GPCR_Rhodpsn,prints_Formyl_pep_rcpt	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_ATII_AT1_rcpt,prints_ATII_rcpt,prints_GPCR_Rhodpsn,prints_Chemokine_rcpt,prints_Formyl_pep_rcpt,prints_Brdyknn_rcpt	-	no_errors	AGTR1	HGNC	ENSG00000144891	tier1			24	0	0.00	27	7	20.59	102	0	0.00	83	21	20.19
GATAD2A	0	genome.wustl.edu	37	19	19576217	19576218	+	In_Frame_Ins	INS	-	-	GAC			TCGA-PC-A5DN-01A-12D-A27P-09	TCGA-PC-A5DN-10A-01D-A27P-09	-	-	-	GAC	-	-	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	60581c5a-e89b-4e0e-bb80-20a3b14f4638	680014f0-e224-4d25-9929-02de0f4b2f44	19	19576217	19576218	-	GAC	INS	GATAD2A	ENST00000358713	human	ensembl	74_37	+1	known	in_frame_ins	c.63_64	p.23in_frame_insD	0.001:0.346	NULL	pfam_Znf_GATA,pfscan_Znf_GATA	-	no_errors	GATAD2A	HGNC	ENSG00000167491	tier1			60	0	0.00	22	6	21.43	71	0	0.00	66	23	25.84
PLGRKT	0	genome.wustl.edu	37	9	5361821	5361822	+	In_Frame_Ins	INS	-	-	ACC			TCGA-PC-A5DN-01A-12D-A27P-09	TCGA-PC-A5DN-10A-01D-A27P-09	-	-	-	ACC	-	-	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	60581c5a-e89b-4e0e-bb80-20a3b14f4638	680014f0-e224-4d25-9929-02de0f4b2f44	9	5361821	5361822	-	ACC	INS	PLGRKT	ENST00000223864	human	ensembl	74_37	-1	known	in_frame_ins	c.149_148	p.50in_frame_insW	1.000:1.000	pfam_DUF2368	pfam_DUF2368	-	no_errors	PLGRKT	HGNC	ENSG00000107020	tier1			75	0	0.00	47	10	17.54	72	0	0.00	56	10	15.15
ENSG00000255622	0	genome.wustl.edu	37	5	140536810	140536813	+	Frame_Shift_Del	DEL	AGAG	AGAG	-			TCGA-PC-A5DN-01A-12D-A27P-09	TCGA-PC-A5DN-10A-01D-A27P-09	AGAG	AGAG	AGAG	-	AGAG	AGAG	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	60581c5a-e89b-4e0e-bb80-20a3b14f4638	680014f0-e224-4d25-9929-02de0f4b2f44	5	140536810	140536813	AGAG	-	DEL	ENSG00000255622	ENST00000539533	human	ensembl	74_37	+1	known	frame_shift_del	c.1234_1237	p.E413fs	1.000:1.000:1.000:1.000	pfam_Cadherin,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin	pfam_Cadherin,pfam_Cadherin_N,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin,prints_Cadherin	-	no_errors	PCDHB17	Uniprot_gn	ENSG00000255622	tier1			91	0	0.00	54	18	25.00	52	0	0.00	50	18	26.47
APOB	0	genome.wustl.edu	37	2	21234572	21234572	+	Missense_Mutation	SNP	C	C	A			TCGA-PC-A5DN-01A-12D-A27P-09	TCGA-PC-A5DN-10A-01D-A27P-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	60581c5a-e89b-4e0e-bb80-20a3b14f4638	680014f0-e224-4d25-9929-02de0f4b2f44	2	21234572	21234572	C	A	SNP	APOB	ENST00000233242	human	ensembl	74_37	-1	known	missense	c.5168	p.S1723I	1.000	NULL	pfam_Lipid_transpt_N,pfam_Vitellinogen_open_b-sht,pfam_ApoB100_C,pfam_Lipid_transpt_open_b-sht,superfamily_Lipid_transp_b-sht_shell,superfamily_Vitellinogen_superhlx,superfamily_ARM-type_fold,smart_Lipid_transpt_N,pfscan_Lipid_transpt_N	-	no_errors	APOB	HGNC	ENSG00000084674	tier1	-	-	90	0	0.00	59	6	9.23	67	0	0.00	53	4	7.02
SCN11A	0	genome.wustl.edu	37	3	38950624	38950624	+	Missense_Mutation	SNP	G	G	A			TCGA-PC-A5DN-01A-12D-A27P-09	TCGA-PC-A5DN-10A-01D-A27P-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	60581c5a-e89b-4e0e-bb80-20a3b14f4638	680014f0-e224-4d25-9929-02de0f4b2f44	3	38950624	38950624	G	A	SNP	SCN11A	ENST00000302328	human	ensembl	74_37	-1	known	missense	c.1163	p.S388F	1.000	pfam_Ion_trans_dom	pfam_Ion_trans_dom,pfam_Na_trans_assoc,prints_Na_channel_asu	-	no_errors	SCN11A	HGNC	ENSG00000168356	tier1	-	-	62	0	0.00	53	7	11.67	114	0	0.00	82	9	9.89
FCGBP	0	genome.wustl.edu	37	19	40363158	40363158	+	Missense_Mutation	SNP	A	A	G			TCGA-PC-A5DN-01A-12D-A27P-09	TCGA-PC-A5DN-10A-01D-A27P-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	60581c5a-e89b-4e0e-bb80-20a3b14f4638	680014f0-e224-4d25-9929-02de0f4b2f44	19	40363158	40363158	A	G	SNP	FCGBP	ENST00000221347	human	ensembl	74_37	-1	known	missense	c.14912	p.L4971P	0.519	pfam_VWF_type-D,smart_VWF_type-D	pfam_VWF_type-D,pfam_Unchr_dom_Cys-rich,pfam_TIL_dom,superfamily_TIL_dom,smart_Fol_N,smart_VWF_type-D,smart_Unchr_dom_Cys-rich,smart_EG-like_dom,smart_VWF_C,smart_VWC_out	-	no_errors	FCGBP	HGNC	ENSG00000090920	tier1	-	-	97	0	0.00	77	11	12.50	39	0	0.00	44	4	8.33
NUAK1	0	genome.wustl.edu	37	12	106460789	106460789	+	Missense_Mutation	SNP	G	G	A			TCGA-PC-A5DN-01A-12D-A27P-09	TCGA-PC-A5DN-10A-01D-A27P-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	60581c5a-e89b-4e0e-bb80-20a3b14f4638	680014f0-e224-4d25-9929-02de0f4b2f44	12	106460789	106460789	G	A	SNP	NUAK1	ENST00000261402	human	ensembl	74_37	-1	known	missense	c.1777	p.P593S	0.910	NULL	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_LipoPS_kinase,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	-	no_errors	NUAK1	HGNC	ENSG00000074590	tier1	-	-	46	0	0.00	112	10	8.20	26	0	0.00	83	7	7.78
TRAPPC9	0	genome.wustl.edu	37	8	140998965	140998965	+	Missense_Mutation	SNP	C	C	G			TCGA-PC-A5DN-01A-12D-A27P-09	TCGA-PC-A5DN-10A-01D-A27P-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	60581c5a-e89b-4e0e-bb80-20a3b14f4638	680014f0-e224-4d25-9929-02de0f4b2f44	8	140998965	140998965	C	G	SNP	TRAPPC9	ENST00000389328	human	ensembl	74_37	-1	known	missense	c.3073	p.A1025P	0.997	NULL	pfam_TRAPP_II_complex_Trs120	-	no_errors	TRAPPC9	HGNC	ENSG00000167632	tier1	-	-	78	0	0.00	51	6	10.53	7	0	0.00	6	0	0.00
ACRC	0	genome.wustl.edu	37	X	70823836	70823836	+	Missense_Mutation	SNP	G	G	T			TCGA-PC-A5DN-01A-12D-A27P-09	TCGA-PC-A5DN-10A-01D-A27P-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	60581c5a-e89b-4e0e-bb80-20a3b14f4638	680014f0-e224-4d25-9929-02de0f4b2f44	X	70823836	70823836	G	T	SNP	ACRC	ENST00000373695	human	ensembl	74_37	+1	known	missense	c.709	p.D237Y	0.014	NULL	pfam_SprT-like_domain,smart_SprT-like_domain	-	no_errors	ACRC	HGNC	ENSG00000147174	tier1	-	-	95	0	0.00	53	28	34.57	0	0	0.00	0	0	0.00
ENSG00000221734	0	genome.wustl.edu	37	9	117554505	117554510	+	R	DEL	ACACAC	ACACAC	-			TCGA-PC-A5DN-01A-12D-A27P-09	TCGA-PC-A5DN-10A-01D-A27P-09	ACACAC	ACACAC					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	60581c5a-e89b-4e0e-bb80-20a3b14f4638	680014f0-e224-4d25-9929-02de0f4b2f44	9	117554505	117554510	ACACAC	-	DEL	ENSG00000221734	ENST00000408807	human	ensembl	74_37	+1	novel	rna	NULL	NULL	0.007:0.007:0.010:0.012:0.014:0.015	-	-	-	no_errors	AL390240.1	Clone_based_ensembl_gene	ENSG00000221734	tier1			0	0	0.00	0	0	0.00	0	0	0.00	0	0	0.00
ENSG00000261200	0	genome.wustl.edu	37	16	33347801	33347817	+	R	DEL	GGCCAGGGCAAAGGTAT	GGCCAGGGCAAAGGTAT	-			TCGA-PC-A5DN-01A-12D-A27P-09	TCGA-PC-A5DN-10A-01D-A27P-09	GGCCAGGGCAAAGGTAT	GGCCAGGGCAAAGGTAT					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	60581c5a-e89b-4e0e-bb80-20a3b14f4638	680014f0-e224-4d25-9929-02de0f4b2f44	16	33347801	33347817	GGCCAGGGCAAAGGTAT	-	DEL	ENSG00000261200	ENST00000568752	human	ensembl	74_37	-1	known	rna	NULL	NULL	1.000:1.000:0.994:0.992:0.993:0.994:0.989:0.989:0.979:0.981:0.984:0.980:0.974:0.965:0.953:0.941:0.945	-	-	-	no_errors	RP11-989E6.10	Clone_based_vega_gene	ENSG00000261200	tier1			0	0	0.00	0	0	0.00	0	0	0.00	0	0	0.00
MIR3156-3	0	genome.wustl.edu	37	21	14778717	14778717	+	R	SNP	G	G	T			TCGA-PC-A5DN-01A-12D-A27P-09	TCGA-PC-A5DN-10A-01D-A27P-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	60581c5a-e89b-4e0e-bb80-20a3b14f4638	680014f0-e224-4d25-9929-02de0f4b2f44	21	14778717	14778717	G	T	SNP	MIR3156-3	ENST00000580304	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.006	-	-	-	no_errors	MIR3156-3	HGNC	ENSG00000266211	tier1	-	-	42	0	0.00	9	10	52.63	1	0	0.00	1	1	50.00
MNX1-AS1	0	genome.wustl.edu	37	7	156803795	156803795	+	R	SNP	G	G	T			TCGA-PC-A5DN-01A-12D-A27P-09	TCGA-PC-A5DN-10A-01D-A27P-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	60581c5a-e89b-4e0e-bb80-20a3b14f4638	680014f0-e224-4d25-9929-02de0f4b2f44	7	156803795	156803795	G	T	SNP	MNX1-AS1	ENST00000480284	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.002	-	-	-	no_errors	MNX1-AS1	HGNC	ENSG00000243479	tier1	-	-	42	0	0.00	42	6	12.50	0	0	0.00	3	0	0.00
NUMBL	0	genome.wustl.edu	37	19	41173893	41173898	+	In_Frame_Del	DEL	TGCTGT	TGCTGT	-			TCGA-PC-A5DN-01A-12D-A27P-09	TCGA-PC-A5DN-10A-01D-A27P-09	TGCTGT	TGCTGT					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	60581c5a-e89b-4e0e-bb80-20a3b14f4638	680014f0-e224-4d25-9929-02de0f4b2f44	19	41173893	41173898	TGCTGT	-	DEL	NUMBL	ENST00000252891	human	ensembl	74_37	-1	known	in_frame_del	c.1310_1305	p.QQ439in_frame_del	1.000:1.000:1.000:1.000:1.000:0.998	pirsf_Numb/numb-like	pfam_Numb_domain,pfam_PTB/PI_dom,pfam_PTB,smart_PTB/PI_dom,pirsf_Numb/numb-like,pfscan_PTB/PI_dom	-	no_errors	NUMBL	HGNC	ENSG00000105245	tier1			0	0	0.00	0	1	100.00	0	0	0.00	0	1	100.00
KMT2D	0	genome.wustl.edu	37	12	49425667	49425667	+	Missense_Mutation	SNP	A	A	G			TCGA-PC-A5DN-01A-12D-A27P-09	TCGA-PC-A5DN-10A-01D-A27P-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	60581c5a-e89b-4e0e-bb80-20a3b14f4638	680014f0-e224-4d25-9929-02de0f4b2f44	12	49425667	49425667	A	G	SNP	KMT2D	ENST00000301067	human	ensembl	74_37	-1	known	missense	c.12821	p.L4274P	0.378	NULL	pfam_Znf_PHD-finger,pfam_SET_dom,pfam_FYrich_C,pfam_FYrich_N,superfamily_Znf_FYVE_PHD,superfamily_HMG_box_dom,smart_Znf_PHD,smart_Znf_RING,smart_HMG_box_dom,smart_FYrich_N,smart_FYrich_C,smart_SET_dom,smart_Post-SET_dom,pfscan_SET_dom,pfscan_Post-SET_dom,pfscan_Znf_PHD-finger,pfscan_Znf_RING	-	no_errors	KMT2D	HGNC	ENSG00000167548	tier1	-	-	127	0	0.00	76	22	22.45	13	0	0.00	21	2	8.70