Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	default_gene_name	gene_name_source	 ensembl_gene_id	tier	dbSNP	GMAF	n_ref_count	n_alt_count	normal_vaf	t_ref_count	t_alt_count	tumor_vaf	n_ref_count_val	n_alt_count_val	normal_vaf_val	t_ref_count_val	t_alt_count_val	tumor_vaf_val
SLC9B1P2	0	genome.wustl.edu	37	2	92102188	92102188	+	R	SNP	T	T	A			TCGA-SG-A6Z7-01A-12D-A32I-09	TCGA-SG-A6Z7-11A-21D-A32I-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1a9b5304-f9e7-4b7f-9c10-bb5e0b659ce7	150e85f0-08f1-445f-86af-41a5bb0f3590	2	92102188	92102188	T	A	SNP	SLC9B1P2	ENST00000606405	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.854	-	-	-	no_errors	SLC9B1P2	HGNC	ENSG00000214329	tier1	-	-	315	1	0.32	390	101	20.53	36	0	0.00	26	3	10.34
TRDN	0	genome.wustl.edu	37	6	123824870	123824870	+	Missense_Mutation	SNP	G	G	C			TCGA-SG-A6Z7-01A-12D-A32I-09	TCGA-SG-A6Z7-11A-21D-A32I-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1a9b5304-f9e7-4b7f-9c10-bb5e0b659ce7	150e85f0-08f1-445f-86af-41a5bb0f3590	6	123824870	123824870	G	C	SNP	TRDN	ENST00000398178	human	ensembl	74_37	-1	known	missense	c.787	p.Q263E	1.000	pfam_Asp-B-hydro/Triadin_dom	pfam_Asp-B-hydro/Triadin_dom	-	no_errors	TRDN	HGNC	ENSG00000186439	tier1	-	-	47	0	0.00	31	57	64.77	76	0	0.00	22	66	75.00
LILRP2	0	genome.wustl.edu	37	19	55220578	55220578	+	R	SNP	T	T	A			TCGA-SG-A6Z7-01A-12D-A32I-09	TCGA-SG-A6Z7-11A-21D-A32I-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1a9b5304-f9e7-4b7f-9c10-bb5e0b659ce7	150e85f0-08f1-445f-86af-41a5bb0f3590	19	55220578	55220578	T	A	SNP	LILRP2	ENST00000413439	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.002	-	-	-	no_errors	LILRP2	HGNC	ENSG00000170858	tier1	-	-	61	0	0.00	21	42	66.67	115	0	0.00	33	41	54.67
ENSG00000226716	0	genome.wustl.edu	37	1	152097427	152097427	+	R	SNP	C	C	T			TCGA-SG-A6Z7-01A-12D-A32I-09	TCGA-SG-A6Z7-11A-21D-A32I-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1a9b5304-f9e7-4b7f-9c10-bb5e0b659ce7	150e85f0-08f1-445f-86af-41a5bb0f3590	1	152097427	152097427	C	T	SNP	ENSG00000226716	ENST00000429230	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.250	-	-	-	no_errors	AL589986.2	Clone_based_vega_gene	ENSG00000226716	tier1	-	-	22	0	0.00	26	18	40.91	98	0	0.00	61	96	60.76
IL12RB2	0	genome.wustl.edu	37	1	67787498	67787498	+	Missense_Mutation	SNP	C	C	T			TCGA-SG-A6Z7-01A-12D-A32I-09	TCGA-SG-A6Z7-11A-21D-A32I-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1a9b5304-f9e7-4b7f-9c10-bb5e0b659ce7	150e85f0-08f1-445f-86af-41a5bb0f3590	1	67787498	67787498	C	T	SNP	IL12RB2	ENST00000262345	human	ensembl	74_37	+1	known	missense	c.290	p.T97I	0.385	pfam_IgC2-like_lig-bd	pfam_Fibronectin_type3,pfam_IgC2-like_lig-bd,pfam_IL-6_rcpt_alpha-bd,superfamily_Fibronectin_type3,smart_Fibronectin_type3,pfscan_Fibronectin_type3	-	no_errors	IL12RB2	HGNC	ENSG00000081985	tier1	-	-	54	0	0.00	63	17	21.25	120	0	0.00	90	23	20.35
SLIT2	0	genome.wustl.edu	37	4	20611715	20611715	+	Missense_Mutation	SNP	G	G	A			TCGA-SG-A6Z7-01A-12D-A32I-09	TCGA-SG-A6Z7-11A-21D-A32I-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1a9b5304-f9e7-4b7f-9c10-bb5e0b659ce7	150e85f0-08f1-445f-86af-41a5bb0f3590	4	20611715	20611715	G	A	SNP	SLIT2	ENST00000504154	human	ensembl	74_37	+1	known	missense	c.3772	p.G1258S	1.000	pfam_Laminin_G,superfamily_ConA-like_lec_gl_sf,smart_Laminin_G,pfscan_Laminin_G	pfam_EG-like_dom,pfam_Laminin_G,pfam_Leu-rich_rpt,pfam_LRR-contain_N,pfam_Cys-rich_flank_reg_C,superfamily_ConA-like_lec_gl_sf,smart_LRR-contain_N,smart_Leu-rich_rpt_typical-subtyp,smart_Cys-rich_flank_reg_C,smart_EGF-like_Ca-bd_dom,smart_EG-like_dom,smart_Fol_N,smart_Laminin_G,smart_Cys_knot_C,pfscan_Cys_knot_C,pfscan_EG-like_dom,pfscan_Laminin_G	-	no_errors	SLIT2	HGNC	ENSG00000145147	tier1	-	-	71	0	0.00	38	30	44.12	130	0	0.00	49	49	50.00
STK17B	0	genome.wustl.edu	37	2	197028100	197028100	+	Missense_Mutation	SNP	C	C	T			TCGA-SG-A6Z7-01A-12D-A32I-09	TCGA-SG-A6Z7-11A-21D-A32I-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1a9b5304-f9e7-4b7f-9c10-bb5e0b659ce7	150e85f0-08f1-445f-86af-41a5bb0f3590	2	197028100	197028100	C	T	SNP	STK17B	ENST00000263955	human	ensembl	74_37	-1	known	missense	c.8	p.R3K	0.982	NULL	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	-	no_errors	STK17B	HGNC	ENSG00000081320	tier1	-	-	125	0	0.00	129	44	25.43	132	0	0.00	90	24	20.87
OR2F1	0	genome.wustl.edu	37	7	143658017	143658017	+	Nonstop_Mutation	SNP	A	A	G			TCGA-SG-A6Z7-01A-12D-A32I-09	TCGA-SG-A6Z7-11A-21D-A32I-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1a9b5304-f9e7-4b7f-9c10-bb5e0b659ce7	150e85f0-08f1-445f-86af-41a5bb0f3590	7	143658017	143658017	A	G	SNP	OR2F1	ENST00000392899	human	ensembl	74_37	+1	known	nonstop	c.954	p.*318W	0.360	NULL	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR2F1	HGNC	ENSG00000213215	tier1	-	-	51	0	0.00	36	20	35.71	86	0	0.00	27	35	56.45
INSL4	0	genome.wustl.edu	37	9	5233767	5233767	+	Missense_Mutation	SNP	T	T	A			TCGA-SG-A6Z7-01A-12D-A32I-09	TCGA-SG-A6Z7-11A-21D-A32I-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1a9b5304-f9e7-4b7f-9c10-bb5e0b659ce7	150e85f0-08f1-445f-86af-41a5bb0f3590	9	5233767	5233767	T	A	SNP	INSL4	ENST00000239316	human	ensembl	74_37	+1	known	missense	c.310	p.L104M	0.001	superfamily_Insulin-like	superfamily_Insulin-like,prints_Placentin,prints_Relaxin	-	no_errors	INSL4	HGNC	ENSG00000120211	tier1	-	-	63	0	0.00	34	35	50.72	147	1	0.68	46	43	47.78
ELL2	0	genome.wustl.edu	37	5	95249513	95249513	+	Missense_Mutation	SNP	C	C	G			TCGA-SG-A6Z7-01A-12D-A32I-09	TCGA-SG-A6Z7-11A-21D-A32I-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1a9b5304-f9e7-4b7f-9c10-bb5e0b659ce7	150e85f0-08f1-445f-86af-41a5bb0f3590	5	95249513	95249513	C	G	SNP	ELL2	ENST00000237853	human	ensembl	74_37	-1	known	missense	c.443	p.R148P	1.000	pfam_R_pol_II_elong_fac_ELL	pfam_R_pol_II_elong_fac_ELL,pfam_Occludin_Rpol2_elong_fac_ELL	-	no_errors	ELL2	HGNC	ENSG00000118985	tier1	-	-	52	0	0.00	31	27	46.55	50	0	0.00	17	16	48.48
ENSG00000206567	0	genome.wustl.edu	37	3	10049212	10049212	+	R	SNP	G	G	A			TCGA-SG-A6Z7-01A-12D-A32I-09	TCGA-SG-A6Z7-11A-21D-A32I-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1a9b5304-f9e7-4b7f-9c10-bb5e0b659ce7	150e85f0-08f1-445f-86af-41a5bb0f3590	3	10049212	10049212	G	A	SNP	ENSG00000206567	ENST00000383808	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.002	-	-	-	no_errors	AC022007.5	Clone_based_vega_gene	ENSG00000206567	tier1	-	-	44	0	0.00	30	21	41.18	53	0	0.00	11	14	56.00
PDE4DIP	0	genome.wustl.edu	37	1	144853254	144853254	+	R	SNP	A	A	G			TCGA-SG-A6Z7-01A-12D-A32I-09	TCGA-SG-A6Z7-11A-21D-A32I-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1a9b5304-f9e7-4b7f-9c10-bb5e0b659ce7	150e85f0-08f1-445f-86af-41a5bb0f3590	1	144853254	144853254	A	G	SNP	PDE4DIP	ENST00000526182	human	ensembl	74_37	-1	known	rna	NULL	NULL	1.000	-	-	-	no_errors	PDE4DIP	HGNC	ENSG00000178104	tier1	-	-	122	1	0.81	126	43	25.44	96	0	0.00	63	33	34.38
ZFC3H1	0	genome.wustl.edu	37	12	72038834	72038834	+	Missense_Mutation	SNP	C	C	G			TCGA-SG-A6Z7-01A-12D-A32I-09	TCGA-SG-A6Z7-11A-21D-A32I-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1a9b5304-f9e7-4b7f-9c10-bb5e0b659ce7	150e85f0-08f1-445f-86af-41a5bb0f3590	12	72038834	72038834	C	G	SNP	ZFC3H1	ENST00000378743	human	ensembl	74_37	-1	known	missense	c.1102	p.E368Q	1.000	NULL	pfam_Putative_zinc-finger_domain,smart_HAT,pfscan_TPR-contain_dom	-	no_errors	ZFC3H1	HGNC	ENSG00000133858	tier1	-	-	64	0	0.00	73	20	21.51	110	0	0.00	93	15	13.89
PIDD	0	genome.wustl.edu	37	11	803282	803282	+	Missense_Mutation	SNP	G	G	C			TCGA-SG-A6Z7-01A-12D-A32I-09	TCGA-SG-A6Z7-11A-21D-A32I-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1a9b5304-f9e7-4b7f-9c10-bb5e0b659ce7	150e85f0-08f1-445f-86af-41a5bb0f3590	11	803282	803282	G	C	SNP	PIDD	ENST00000347755	human	ensembl	74_37	-1	known	missense	c.601	p.L201V	1.000	pfam_Leu-rich_rpt,smart_Leu-rich_rpt_typical-subtyp	pfam_Peptidase_S68_pidd,pfam_Death_domain,pfam_Leu-rich_rpt,pfam_ZU5,superfamily_DEATH-like_dom,smart_Leu-rich_rpt_typical-subtyp,smart_Death_domain,pfscan_Death_domain,pfscan_ZU5	-	no_errors	PIDD	HGNC	ENSG00000177595	tier1	-	-	59	0	0.00	37	16	30.19	33	0	0.00	15	3	16.67
PPARGC1A	0	genome.wustl.edu	37	4	23833358	23833358	+	Missense_Mutation	SNP	T	T	A			TCGA-SG-A6Z7-01A-12D-A32I-09	TCGA-SG-A6Z7-11A-21D-A32I-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1a9b5304-f9e7-4b7f-9c10-bb5e0b659ce7	150e85f0-08f1-445f-86af-41a5bb0f3590	4	23833358	23833358	T	A	SNP	PPARGC1A	ENST00000264867	human	ensembl	74_37	-1	known	missense	c.251	p.N84I	1.000	NULL	pfam_RRM_dom,smart_RRM_dom,pfscan_RRM_dom	-	no_errors	PPARGC1A	HGNC	ENSG00000109819	tier1	-	-	39	0	0.00	33	16	32.65	76	0	0.00	24	25	51.02
SNORD3A	0	genome.wustl.edu	37	17	19091345	19091345	+	R	SNP	G	G	A			TCGA-SG-A6Z7-01A-12D-A32I-09	TCGA-SG-A6Z7-11A-21D-A32I-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1a9b5304-f9e7-4b7f-9c10-bb5e0b659ce7	150e85f0-08f1-445f-86af-41a5bb0f3590	17	19091345	19091345	G	A	SNP	SNORD3A	ENST00000365494	human	ensembl	74_37	+1	known	rna	NULL	NULL	1.000	-	-	-	no_errors	SNORD3A	HGNC	ENSG00000263934	tier1	-	-	176	0	0.00	65	54	45.38	149	0	0.00	34	12	26.09
PASK	0	genome.wustl.edu	37	2	242062177	242062177	+	Nonsense_Mutation	SNP	C	C	T			TCGA-SG-A6Z7-01A-12D-A32I-09	TCGA-SG-A6Z7-11A-21D-A32I-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1a9b5304-f9e7-4b7f-9c10-bb5e0b659ce7	150e85f0-08f1-445f-86af-41a5bb0f3590	2	242062177	242062177	C	T	SNP	PASK	ENST00000358649	human	ensembl	74_37	-1	known	nonsense	c.3042	p.W1014*	1.000	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_PAS_fold,superfamily_Kinase-like_dom,superfamily_PAS,smart_PAS,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_PAS,pfscan_Prot_kinase_dom,tigrfam_PAS	-	no_errors	PASK	HGNC	ENSG00000115687	tier1	-	-	36	0	0.00	42	54	56.25	93	0	0.00	53	42	44.21
SYT8	0	genome.wustl.edu	37	11	1852913	1852913	+	Missense_Mutation	SNP	G	G	C			TCGA-SG-A6Z7-01A-12D-A32I-09	TCGA-SG-A6Z7-11A-21D-A32I-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1a9b5304-f9e7-4b7f-9c10-bb5e0b659ce7	150e85f0-08f1-445f-86af-41a5bb0f3590	11	1852913	1852913	G	C	SNP	SYT8	ENST00000535046	human	ensembl	74_37	+1	known	missense	c.231	p.E77D	0.004	NULL	NULL	-	no_errors	SYT8	HGNC	ENSG00000149043	tier1	-	-	83	0	0.00	76	27	26.21	51	0	0.00	14	5	26.32
LCE6A	0	genome.wustl.edu	37	1	152816161	152816161	+	Missense_Mutation	SNP	G	G	C			TCGA-SG-A6Z7-01A-12D-A32I-09	TCGA-SG-A6Z7-11A-21D-A32I-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1a9b5304-f9e7-4b7f-9c10-bb5e0b659ce7	150e85f0-08f1-445f-86af-41a5bb0f3590	1	152816161	152816161	G	C	SNP	LCE6A	ENST00000431011	human	ensembl	74_37	+1	known	missense	c.165	p.R55S	0.000	NULL	NULL	-	no_errors	LCE6A	HGNC	ENSG00000235942	tier1	-	-	51	0	0.00	98	10	9.26	92	0	0.00	108	22	16.92
HSD17B11	0	genome.wustl.edu	37	4	88303510	88303510	+	Missense_Mutation	SNP	C	C	T			TCGA-SG-A6Z7-01A-12D-A32I-09	TCGA-SG-A6Z7-11A-21D-A32I-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1a9b5304-f9e7-4b7f-9c10-bb5e0b659ce7	150e85f0-08f1-445f-86af-41a5bb0f3590	4	88303510	88303510	C	T	SNP	HSD17B11	ENST00000358290	human	ensembl	74_37	-1	known	missense	c.215	p.G72E	1.000	pfam_DH_sc/Rdtase_SDR,pfam_PKS_KR	pfam_DH_sc/Rdtase_SDR,pfam_PKS_KR,prints_Glc/ribitol_DH,prints_DH_sc/Rdtase_SDR	-	no_errors	HSD17B11	HGNC	ENSG00000198189	tier1	-	-	85	0	0.00	75	7	8.54	119	0	0.00	73	10	12.05
PRKDC	0	genome.wustl.edu	37	8	48765289	48765289	+	Missense_Mutation	SNP	G	G	C			TCGA-SG-A6Z7-01A-12D-A32I-09	TCGA-SG-A6Z7-11A-21D-A32I-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1a9b5304-f9e7-4b7f-9c10-bb5e0b659ce7	150e85f0-08f1-445f-86af-41a5bb0f3590	8	48765289	48765289	G	C	SNP	PRKDC	ENST00000314191	human	ensembl	74_37	-1	known	missense	c.6947	p.A2316G	1.000	superfamily_ARM-type_fold	pfam_NUC194,pfam_PIK-rel_kinase_FAT,pfam_PI3/4_kinase_cat_dom,pfam_FATC,superfamily_Kinase-like_dom,superfamily_ARM-type_fold,smart_PI3/4_kinase_cat_dom,pfscan_PIK_FAT,pfscan_FATC,pfscan_PI3/4_kinase_cat_dom	-	no_errors	PRKDC	HGNC	ENSG00000253729	tier1	-	-	48	0	0.00	58	19	24.68	69	0	0.00	49	6	10.91
TIPARP	0	genome.wustl.edu	37	3	156396350	156396350	+	Silent	SNP	C	C	T			TCGA-SG-A6Z7-01A-12D-A32I-09	TCGA-SG-A6Z7-11A-21D-A32I-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1a9b5304-f9e7-4b7f-9c10-bb5e0b659ce7	150e85f0-08f1-445f-86af-41a5bb0f3590	3	156396350	156396350	C	T	SNP	TIPARP	ENST00000295924	human	ensembl	74_37	+1	known	silent	c.864	p.H288	1.000	NULL	pfam_Poly(ADP-ribose)pol_cat_dom,pfscan_WWE-dom,pfscan_Poly(ADP-ribose)pol_cat_dom	-	no_errors	TIPARP	HGNC	ENSG00000163659	tier1	-	-	51	0	0.00	15	15	50.00	129	1	0.76	43	47	52.22
PI4KB	0	genome.wustl.edu	37	1	151288732	151288732	+	Nonsense_Mutation	SNP	C	C	A			TCGA-SG-A6Z7-01A-12D-A32I-09	TCGA-SG-A6Z7-11A-21D-A32I-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1a9b5304-f9e7-4b7f-9c10-bb5e0b659ce7	150e85f0-08f1-445f-86af-41a5bb0f3590	1	151288732	151288732	C	A	SNP	PI4KB	ENST00000271657	human	ensembl	74_37	-1	known	nonsense	c.262	p.E88*	0.991	NULL	pfam_PI3/4_kinase_cat_dom,superfamily_Kinase-like_dom,smart_PI3/4_kinase_cat_dom,pfscan_PI3/4_kinase_cat_dom	-	no_errors	PI4KB	HGNC	ENSG00000143393	tier1	-	-	27	0	0.00	27	6	18.18	73	0	0.00	104	13	11.02
CCDC27	0	genome.wustl.edu	37	1	3683994	3683994	+	Missense_Mutation	SNP	G	G	C			TCGA-SG-A6Z7-01A-12D-A32I-09	TCGA-SG-A6Z7-11A-21D-A32I-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1a9b5304-f9e7-4b7f-9c10-bb5e0b659ce7	150e85f0-08f1-445f-86af-41a5bb0f3590	1	3683994	3683994	G	C	SNP	CCDC27	ENST00000294600	human	ensembl	74_37	+1	known	missense	c.1728	p.E576D	0.288	NULL	superfamily_Prefoldin	-	no_errors	CCDC27	HGNC	ENSG00000162592	tier1	-	-	28	0	0.00	16	16	50.00	46	0	0.00	20	15	42.86
ENSG00000268823	0	genome.wustl.edu	37	19	22786189	22786189	+	R	SNP	C	C	T			TCGA-SG-A6Z7-01A-12D-A32I-09	TCGA-SG-A6Z7-11A-21D-A32I-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1a9b5304-f9e7-4b7f-9c10-bb5e0b659ce7	150e85f0-08f1-445f-86af-41a5bb0f3590	19	22786189	22786189	C	T	SNP	ENSG00000268823	ENST00000599738	human	ensembl	74_37	+1	known	rna	NULL	NULL	1.000	-	-	-	no_errors	CTC-457E21.6	Clone_based_vega_gene	ENSG00000268823	tier1	-	-	38	0	0.00	50	22	30.56	48	0	0.00	31	8	20.51
CNGB1	0	genome.wustl.edu	37	16	57954314	57954314	+	Missense_Mutation	SNP	G	G	T			TCGA-SG-A6Z7-01A-12D-A32I-09	TCGA-SG-A6Z7-11A-21D-A32I-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1a9b5304-f9e7-4b7f-9c10-bb5e0b659ce7	150e85f0-08f1-445f-86af-41a5bb0f3590	16	57954314	57954314	G	T	SNP	CNGB1	ENST00000251102	human	ensembl	74_37	-1	known	missense	c.1778	p.S593Y	1.000	NULL	pfam_cNMP-bd_dom,superfamily_cNMP-bd-like,smart_cNMP-bd_dom,pfscan_cNMP-bd_dom	-	no_errors	CNGB1	HGNC	ENSG00000070729	tier1	-	-	57	0	0.00	40	29	42.03	82	0	0.00	35	29	45.31
C9orf139	0	genome.wustl.edu	37	9	139927527	139927527	+	Silent	SNP	G	G	T			TCGA-SG-A6Z7-01A-12D-A32I-09	TCGA-SG-A6Z7-11A-21D-A32I-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1a9b5304-f9e7-4b7f-9c10-bb5e0b659ce7	150e85f0-08f1-445f-86af-41a5bb0f3590	9	139927527	139927527	G	T	SNP	C9orf139	ENST00000314330	human	ensembl	74_37	+1	known	silent	c.12	p.R4	0.006	NULL	NULL	-	no_errors	C9orf139	HGNC	ENSG00000180539	tier1	-	-	36	0	0.00	38	7	15.56	27	0	0.00	18	6	25.00
ABT1	0	genome.wustl.edu	37	6	26597314	26597314	+	Missense_Mutation	SNP	C	C	T			TCGA-SG-A6Z7-01A-12D-A32I-09	TCGA-SG-A6Z7-11A-21D-A32I-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1a9b5304-f9e7-4b7f-9c10-bb5e0b659ce7	150e85f0-08f1-445f-86af-41a5bb0f3590	6	26597314	26597314	C	T	SNP	ABT1	ENST00000274849	human	ensembl	74_37	+1	known	missense	c.104	p.A35V	0.001	NULL	NULL	-	no_errors	ABT1	HGNC	ENSG00000146109	tier1	-	-	33	0	0.00	46	27	36.99	29	0	0.00	40	8	16.33
SLC4A1	0	genome.wustl.edu	37	17	42327873	42327873	+	Nonsense_Mutation	SNP	C	C	A			TCGA-SG-A6Z7-01A-12D-A32I-09	TCGA-SG-A6Z7-11A-21D-A32I-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1a9b5304-f9e7-4b7f-9c10-bb5e0b659ce7	150e85f0-08f1-445f-86af-41a5bb0f3590	17	42327873	42327873	C	A	SNP	SLC4A1	ENST00000262418	human	ensembl	74_37	-1	known	nonsense	c.2689	p.E897*	1.000	tigrfam_HCO3_transpt_euk	pfam_HCO3_transpt_C,pfam_Band3_cytoplasmic_dom,superfamily_PTrfase/Anion_transptr,prints_HCO3_transpt_euk,prints_Anion_exchange,prints_Anion_exchange_1,tigrfam_HCO3_transpt_euk	-	no_errors	SLC4A1	HGNC	ENSG00000004939	tier1	-	-	53	0	0.00	36	17	32.08	69	0	0.00	28	21	42.86
CTCF	0	genome.wustl.edu	37	16	67644737	67644737	+	Missense_Mutation	SNP	T	T	C			TCGA-SG-A6Z7-01A-12D-A32I-09	TCGA-SG-A6Z7-11A-21D-A32I-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1a9b5304-f9e7-4b7f-9c10-bb5e0b659ce7	150e85f0-08f1-445f-86af-41a5bb0f3590	16	67644737	67644737	T	C	SNP	CTCF	ENST00000264010	human	ensembl	74_37	+1	known	missense	c.2	p.M1T	1.000	NULL	pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2	-	no_errors	CTCF	HGNC	ENSG00000102974	tier1	-	-	99	0	0.00	64	54	45.76	92	0	0.00	47	36	42.86
LRRK2	0	genome.wustl.edu	37	12	40688653	40688653	+	Missense_Mutation	SNP	A	A	G			TCGA-SG-A6Z7-01A-12D-A32I-09	TCGA-SG-A6Z7-11A-21D-A32I-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1a9b5304-f9e7-4b7f-9c10-bb5e0b659ce7	150e85f0-08f1-445f-86af-41a5bb0f3590	12	40688653	40688653	A	G	SNP	LRRK2	ENST00000298910	human	ensembl	74_37	+1	known	missense	c.2815	p.I939V	0.303	NULL	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_MIRO-like,pfam_Small_GTPase,pfam_Leu-rich_rpt,pfam_Small_GTPase_ARF/SAR,superfamily_Kinase-like_dom,superfamily_P-loop_NTPase,superfamily_ARM-type_fold,superfamily_WD40_repeat_dom,smart_Leu-rich_rpt_typical-subtyp,smart_Small_GTPase_Rab_type,smart_Tyr_kinase_cat_dom,smart_Ser/Thr_dual-sp_kinase_dom,prints_Small_GTPase,prints_Ser-Thr/Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom,tigrfam_Small_GTP-bd_dom	-	no_errors	LRRK2	HGNC	ENSG00000188906	tier1	-	-	118	0	0.00	40	48	54.55	64	0	0.00	17	40	70.18
CKLF	0	genome.wustl.edu	37	16	66597032	66597032	+	Missense_Mutation	SNP	T	T	A			TCGA-SG-A6Z7-01A-12D-A32I-09	TCGA-SG-A6Z7-11A-21D-A32I-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1a9b5304-f9e7-4b7f-9c10-bb5e0b659ce7	150e85f0-08f1-445f-86af-41a5bb0f3590	16	66597032	66597032	T	A	SNP	CKLF	ENST00000264001	human	ensembl	74_37	+1	known	missense	c.245	p.I82N	1.000	NULL	NULL	-	no_errors	CKLF	HGNC	ENSG00000217555	tier1	-	-	71	0	0.00	46	33	41.77	105	0	0.00	52	37	41.57
SYNE2	0	genome.wustl.edu	37	14	64465047	64465047	+	Splice_Site	SNP	G	G	A			TCGA-SG-A6Z7-01A-12D-A32I-09	TCGA-SG-A6Z7-11A-21D-A32I-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1a9b5304-f9e7-4b7f-9c10-bb5e0b659ce7	150e85f0-08f1-445f-86af-41a5bb0f3590	14	64465047	64465047	G	A	SNP	SYNE2	ENST00000358025	human	ensembl	74_37	+1	known	splice_site	c.3353+1	e25+1	1.000	-	-	-	no_errors	SYNE2	HGNC	ENSG00000054654	tier1	-	-	79	0	0.00	92	8	8.00	126	0	0.00	89	12	11.88
RNF219	0	genome.wustl.edu	37	13	79190272	79190272	+	Missense_Mutation	SNP	C	C	G			TCGA-SG-A6Z7-01A-12D-A32I-09	TCGA-SG-A6Z7-11A-21D-A32I-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1a9b5304-f9e7-4b7f-9c10-bb5e0b659ce7	150e85f0-08f1-445f-86af-41a5bb0f3590	13	79190272	79190272	C	G	SNP	RNF219	ENST00000282003	human	ensembl	74_37	-1	known	missense	c.1624	p.D542H	1.000	NULL	pfscan_Znf_RING	-	no_errors	RNF219	HGNC	ENSG00000152193	tier1	-	-	39	0	0.00	21	10	32.26	137	1	0.72	62	26	29.55
KC3	0	genome.wustl.edu	37	1	111215812	111215812	+	Silent	SNP	G	G	A			TCGA-SG-A6Z7-01A-12D-A32I-09	TCGA-SG-A6Z7-11A-21D-A32I-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1a9b5304-f9e7-4b7f-9c10-bb5e0b659ce7	150e85f0-08f1-445f-86af-41a5bb0f3590	1	111215812	111215812	G	A	SNP	KC3	ENST00000369769	human	ensembl	74_37	-1	known	silent	c.1620	p.S540	0.998	NULL	pfam_Ion_trans_dom,pfam_T1-type_BTB,pfam_2pore_dom_K_chnl_dom,superfamily_BTB/POZ_fold,smart_BTB/POZ-like,prints_K_chnl,prints_K_chnl_volt-dep_Kv1.3,prints_K_chnl_volt-dep_Kv1,prints_K_chnl_volt-dep_Kv	-	no_errors	KC3	HGNC	ENSG00000177272	tier1	-	-	64	0	0.00	41	35	45.45	141	0	0.00	57	40	41.24
NOL10	0	genome.wustl.edu	37	2	10811749	10811749	+	Missense_Mutation	SNP	C	C	G			TCGA-SG-A6Z7-01A-12D-A32I-09	TCGA-SG-A6Z7-11A-21D-A32I-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1a9b5304-f9e7-4b7f-9c10-bb5e0b659ce7	150e85f0-08f1-445f-86af-41a5bb0f3590	2	10811749	10811749	C	G	SNP	NOL10	ENST00000381685	human	ensembl	74_37	-1	known	missense	c.395	p.R132T	1.000	superfamily_WD40_repeat_dom	pfam_NUC153,superfamily_WD40_repeat_dom,smart_WD40_repeat	-	no_errors	NOL10	HGNC	ENSG00000115761	tier1	-	-	81	0	0.00	63	44	41.12	115	0	0.00	72	37	33.94
LRRIQ3	0	genome.wustl.edu	37	1	74549765	74549765	+	R	SNP	C	C	A			TCGA-SG-A6Z7-01A-12D-A32I-09	TCGA-SG-A6Z7-11A-21D-A32I-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1a9b5304-f9e7-4b7f-9c10-bb5e0b659ce7	150e85f0-08f1-445f-86af-41a5bb0f3590	1	74549765	74549765	C	A	SNP	LRRIQ3	ENST00000468759	human	ensembl	74_37	-1	known	rna	NULL	NULL	1.000	-	-	-	no_errors	LRRIQ3	HGNC	ENSG00000162620	tier1	-	-	37	0	0.00	30	11	26.83	102	0	0.00	55	18	24.66
PIDD	0	genome.wustl.edu	37	11	803302	803302	+	Missense_Mutation	SNP	G	G	T			TCGA-SG-A6Z7-01A-12D-A32I-09	TCGA-SG-A6Z7-11A-21D-A32I-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1a9b5304-f9e7-4b7f-9c10-bb5e0b659ce7	150e85f0-08f1-445f-86af-41a5bb0f3590	11	803302	803302	G	T	SNP	PIDD	ENST00000347755	human	ensembl	74_37	-1	known	missense	c.581	p.S194Y	0.000	smart_Leu-rich_rpt_typical-subtyp	pfam_Peptidase_S68_pidd,pfam_Death_domain,pfam_Leu-rich_rpt,pfam_ZU5,superfamily_DEATH-like_dom,smart_Leu-rich_rpt_typical-subtyp,smart_Death_domain,pfscan_Death_domain,pfscan_ZU5	-	no_errors	PIDD	HGNC	ENSG00000177595	tier1	-	-	65	0	0.00	39	20	33.90	31	0	0.00	16	3	15.79
MKL2	0	genome.wustl.edu	37	16	14340547	14340547	+	Missense_Mutation	SNP	C	C	T			TCGA-SG-A6Z7-01A-12D-A32I-09	TCGA-SG-A6Z7-11A-21D-A32I-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1a9b5304-f9e7-4b7f-9c10-bb5e0b659ce7	150e85f0-08f1-445f-86af-41a5bb0f3590	16	14340547	14340547	C	T	SNP	MKL2	ENST00000341243	human	ensembl	74_37	+1	known	missense	c.1397	p.S466L	0.090	NULL	pfam_RPEL_repeat,pfam_SAP_dom,smart_RPEL_repeat,smart_SAP_dom,pfscan_RPEL_repeat,pfscan_SAP_dom	-	no_errors	MKL2	HGNC	ENSG00000186260	tier1	-	-	58	0	0.00	35	37	51.39	94	0	0.00	39	28	41.79
HOXC8	0	genome.wustl.edu	37	12	54403298	54403298	+	Missense_Mutation	SNP	G	G	T			TCGA-SG-A6Z7-01A-12D-A32I-09	TCGA-SG-A6Z7-11A-21D-A32I-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1a9b5304-f9e7-4b7f-9c10-bb5e0b659ce7	150e85f0-08f1-445f-86af-41a5bb0f3590	12	54403298	54403298	G	T	SNP	HOXC8	ENST00000040584	human	ensembl	74_37	+1	known	missense	c.230	p.C77F	1.000	NULL	pfam_Homeobox_dom,superfamily_Homeodomain-like,smart_Homeobox_dom,pfscan_Homeobox_dom,prints_Homeobox_metazoa,prints_HTH_motif	-	no_errors	HOXC8	HGNC	ENSG00000037965	tier1	-	-	67	0	0.00	50	24	32.00	31	0	0.00	19	3	13.64
MTHFS	0	genome.wustl.edu	37	15	80181626	80181626	+	Missense_Mutation	SNP	T	T	C			TCGA-SG-A6Z7-01A-12D-A32I-09	TCGA-SG-A6Z7-11A-21D-A32I-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1a9b5304-f9e7-4b7f-9c10-bb5e0b659ce7	150e85f0-08f1-445f-86af-41a5bb0f3590	15	80181626	80181626	T	C	SNP	MTHFS	ENST00000258874	human	ensembl	74_37	-1	known	missense	c.188	p.E63G	0.994	pfam_FTHF_cligase,pirsf_FTHF_cligase,tigrfam_FTHF_cligase	pfam_FTHF_cligase,pirsf_FTHF_cligase,tigrfam_FTHF_cligase	-	no_errors	MTHFS	HGNC	ENSG00000136371	tier1	-	-	89	0	0.00	45	41	47.67	69	0	0.00	23	22	48.89
PASK	0	genome.wustl.edu	37	2	242062301	242062301	+	Missense_Mutation	SNP	C	C	T			TCGA-SG-A6Z7-01A-12D-A32I-09	TCGA-SG-A6Z7-11A-21D-A32I-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1a9b5304-f9e7-4b7f-9c10-bb5e0b659ce7	150e85f0-08f1-445f-86af-41a5bb0f3590	2	242062301	242062301	C	T	SNP	PASK	ENST00000358649	human	ensembl	74_37	-1	known	missense	c.2918	p.R973K	0.010	NULL	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_PAS_fold,superfamily_Kinase-like_dom,superfamily_PAS,smart_PAS,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_PAS,pfscan_Prot_kinase_dom,tigrfam_PAS	-	no_errors	PASK	HGNC	ENSG00000115687	tier1	-	-	32	0	0.00	40	38	48.72	65	0	0.00	57	29	33.72
VCP	0	genome.wustl.edu	37	9	35060455	35060455	+	Missense_Mutation	SNP	T	T	C			TCGA-SG-A6Z7-01A-12D-A32I-09	TCGA-SG-A6Z7-11A-21D-A32I-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1a9b5304-f9e7-4b7f-9c10-bb5e0b659ce7	150e85f0-08f1-445f-86af-41a5bb0f3590	9	35060455	35060455	T	C	SNP	VCP	ENST00000358901	human	ensembl	74_37	-1	known	missense	c.1550	p.Y517C	1.000	pfam_ATPase_AAA_core,pfam_D_helicase_Holl-junc_RuvB_N,superfamily_P-loop_NTPase,smart_AAA+_ATPase,tigrfam_AAA_ATPase_CDC48	pfam_ATPase_AAA_core,pfam_CDC4_N-term_subdom,pfam_D_helicase_Holl-junc_RuvB_N,pfam_Cdc48_dom2,pfam_ATPase_dyneun-rel_AAA,pfam_ATPase_AAA-2,pfam_Vps4_C,superfamily_P-loop_NTPase,superfamily_Asp_de-COase-like_dom,smart_AAA+_ATPase,tigrfam_AAA_ATPase_CDC48	-	no_errors	VCP	HGNC	ENSG00000165280	tier1	-	-	48	0	0.00	45	28	38.36	132	0	0.00	52	53	50.48
STK17B	0	genome.wustl.edu	37	2	197028089	197028089	+	Missense_Mutation	SNP	C	C	G			TCGA-SG-A6Z7-01A-12D-A32I-09	TCGA-SG-A6Z7-11A-21D-A32I-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1a9b5304-f9e7-4b7f-9c10-bb5e0b659ce7	150e85f0-08f1-445f-86af-41a5bb0f3590	2	197028089	197028089	C	G	SNP	STK17B	ENST00000263955	human	ensembl	74_37	-1	known	missense	c.19	p.D7H	1.000	NULL	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	-	no_errors	STK17B	HGNC	ENSG00000081320	tier1	-	-	118	0	0.00	126	41	24.55	134	1	0.74	89	24	21.24
CALCB	0	genome.wustl.edu	37	11	15098923	15098923	+	Missense_Mutation	SNP	A	A	T			TCGA-SG-A6Z7-01A-12D-A32I-09	TCGA-SG-A6Z7-11A-21D-A32I-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1a9b5304-f9e7-4b7f-9c10-bb5e0b659ce7	150e85f0-08f1-445f-86af-41a5bb0f3590	11	15098923	15098923	A	T	SNP	CALCB	ENST00000324229	human	ensembl	74_37	+1	known	missense	c.316	p.S106C	1.000	pfam_Procalcitonin/adrenomedullin,smart_Calcitonin_peptide-like,prints_Calcitonin_gene-rel_peptide,prints_Pro-islet_amyloid_polypep	pfam_Procalcitonin/adrenomedullin,smart_Calcitonin_peptide-like,prints_Calcitonin_gene-rel_peptide,prints_Pro-islet_amyloid_polypep	-	no_errors	CALCB	HGNC	ENSG00000175868	tier1	-	-	27	0	0.00	7	33	82.50	14	0	0.00	3	3	50.00
CTR9	0	genome.wustl.edu	37	11	10772978	10772978	+	Missense_Mutation	SNP	G	G	C			TCGA-SG-A6Z7-01A-12D-A32I-09	TCGA-SG-A6Z7-11A-21D-A32I-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1a9b5304-f9e7-4b7f-9c10-bb5e0b659ce7	150e85f0-08f1-445f-86af-41a5bb0f3590	11	10772978	10772978	G	C	SNP	CTR9	ENST00000361367	human	ensembl	74_37	+1	known	missense	c.19	p.E7Q	1.000	NULL	pfam_TPR_1,smart_TPR_repeat,pfscan_TPR_repeat,pfscan_TPR-contain_dom	-	no_errors	CTR9	HGNC	ENSG00000198730	tier1	-	-	45	0	0.00	38	8	17.39	36	0	0.00	9	2	18.18
MYH3	0	genome.wustl.edu	37	17	10533415	10533415	+	Silent	SNP	C	C	T			TCGA-SG-A6Z7-01A-12D-A32I-09	TCGA-SG-A6Z7-11A-21D-A32I-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1a9b5304-f9e7-4b7f-9c10-bb5e0b659ce7	150e85f0-08f1-445f-86af-41a5bb0f3590	17	10533415	10533415	C	T	SNP	MYH3	ENST00000226209	human	ensembl	74_37	-1	known	silent	c.5556	p.T1852	0.172	pfam_Myosin_tail	pfam_Myosin_tail,pfam_Myosin_head_motor_dom,pfam_Myosin_N,superfamily_P-loop_NTPase,superfamily_Prefoldin,smart_Myosin_head_motor_dom,pfscan_IQ_motif_EF-hand-BS,prints_Myosin_head_motor_dom	-	no_errors	MYH3	HGNC	ENSG00000109063	tier1	-	-	63	0	0.00	1	41	97.62	123	0	0.00	7	50	87.72
NRDE2	0	genome.wustl.edu	37	14	90798307	90798307	+	R	SNP	G	G	T			TCGA-SG-A6Z7-01A-12D-A32I-09	TCGA-SG-A6Z7-11A-21D-A32I-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1a9b5304-f9e7-4b7f-9c10-bb5e0b659ce7	150e85f0-08f1-445f-86af-41a5bb0f3590	14	90798307	90798307	G	T	SNP	NRDE2	ENST00000557106	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	NRDE2	HGNC	ENSG00000119720	tier1	-	-	26	0	0.00	28	11	28.21	11	0	0.00	9	4	30.77
ZSWIM4	0	genome.wustl.edu	37	19	13915823	13915823	+	Frame_Shift_Del	DEL	G	G	-			TCGA-SG-A6Z7-01A-12D-A32I-09	TCGA-SG-A6Z7-11A-21D-A32I-09	G	G	G	-	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1a9b5304-f9e7-4b7f-9c10-bb5e0b659ce7	150e85f0-08f1-445f-86af-41a5bb0f3590	19	13915823	13915823	G	-	DEL	ZSWIM4	ENST00000254323	human	ensembl	74_37	+1	known	frame_shift_del	c.573	p.L192fs	0.091	NULL	pfscan_Znf_SWIM	-	no_errors	ZSWIM4	HGNC	ENSG00000132003	tier1			26	0	0.00	13	4	23.53	21	0	0.00	6	5	45.45
F8	0	genome.wustl.edu	37	X	154159234	154159234	+	Missense_Mutation	SNP	T	T	G			TCGA-SG-A6Z7-01A-12D-A32I-09	TCGA-SG-A6Z7-11A-21D-A32I-09	T	T	T	G	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1a9b5304-f9e7-4b7f-9c10-bb5e0b659ce7	150e85f0-08f1-445f-86af-41a5bb0f3590	X	154159234	154159234	T	G	SNP	F8	ENST00000360256	human	ensembl	74_37	-1	known	missense	c.2831	p.K944T	0.028	NULL	pfam_Coagulation_fac_5/8-C_type_dom,pfam_Cu-oxidase_3,pfam_Cu-oxidase_2,superfamily_Galactose-bd-like,superfamily_Cupredoxin,smart_Coagulation_fac_5/8-C_type_dom,pfscan_Coagulation_fac_5/8-C_type_dom	-	no_errors	F8	HGNC	ENSG00000185010	tier1	-	-	28	0	0.00	35	4	10.26	121	1	0.82	64	5	7.25
GPHN	0	genome.wustl.edu	37	14	67647600	67647600	+	Silent	SNP	C	C	T			TCGA-SG-A6Z7-01A-12D-A32I-09	TCGA-SG-A6Z7-11A-21D-A32I-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1a9b5304-f9e7-4b7f-9c10-bb5e0b659ce7	150e85f0-08f1-445f-86af-41a5bb0f3590	14	67647600	67647600	C	T	SNP	GPHN	ENST00000478722	human	ensembl	74_37	+1	known	silent	c.2256	p.Y752	0.174	pfam_MoeA_C_domain_IV,superfamily_MoeA_C_domain_IV	pfam_Mopterin-bd_dom,pfam_MoeA_linker/N,pfam_MoeA_C_domain_IV,superfamily_MoeA_linker/N,superfamily_Mopterin-bd_dom,superfamily_MoeA_C_domain_IV,smart_Mopterin-bd_dom,tigrfam_Mo_cofactor_synthesis	-	no_errors	GPHN	HGNC	ENSG00000171723	tier1	-	-	50	0	0.00	65	10	13.33	114	0	0.00	96	7	6.80
FAT1	0	genome.wustl.edu	37	4	187629366	187629366	+	Missense_Mutation	SNP	C	C	T			TCGA-SG-A6Z7-01A-12D-A32I-09	TCGA-SG-A6Z7-11A-21D-A32I-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1a9b5304-f9e7-4b7f-9c10-bb5e0b659ce7	150e85f0-08f1-445f-86af-41a5bb0f3590	4	187629366	187629366	C	T	SNP	FAT1	ENST00000441802	human	ensembl	74_37	-1	known	missense	c.1616	p.R539H	0.973	pfam_Cadherin,superfamily_Cadherin-like,smart_Cadherin,prints_Cadherin,pfscan_Cadherin	pfam_Cadherin,pfam_Laminin_G,pfam_EG-like_dom,pfam_EGF-like_Ca-bd_dom,superfamily_ConA-like_lec_gl_sf,superfamily_Cadherin-like,smart_Cadherin,smart_EG-like_dom,smart_Laminin_G,smart_EGF-like_Ca-bd_dom,prints_Cadherin,pfscan_EG-like_dom,pfscan_Laminin_G,pfscan_Cadherin	-	no_errors	FAT1	HGNC	ENSG00000083857	tier1	-	-	39	0	0.00	35	8	18.60	150	0	0.00	86	7	7.53
LRP8	0	genome.wustl.edu	37	1	53728180	53728180	+	Missense_Mutation	SNP	T	T	C			TCGA-SG-A6Z7-01A-12D-A32I-09	TCGA-SG-A6Z7-11A-21D-A32I-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	1a9b5304-f9e7-4b7f-9c10-bb5e0b659ce7	150e85f0-08f1-445f-86af-41a5bb0f3590	1	53728180	53728180	T	C	SNP	LRP8	ENST00000306052	human	ensembl	74_37	-1	known	missense	c.1712	p.N571S	1.000	pfam_LDLR_classB_rpt,superfamily_Growth_fac_rcpt_N_dom,smart_LDLR_classB_rpt,pfscan_LDLR_classB_rpt	pfam_LDrepeatLR_classA_rpt,pfam_LDLR_classB_rpt,pfam_EGF-like_Ca-bd_dom,superfamily_Growth_fac_rcpt_N_dom,superfamily_LDrepeatLR_classA_rpt,smart_LDrepeatLR_classA_rpt,smart_EG-like_dom,smart_EGF-like_Ca-bd_dom,smart_LDLR_classB_rpt,pfscan_LDrepeatLR_classA_rpt,pfscan_LDLR_classB_rpt,prints_LDrepeatLR_classA_rpt	-	no_errors	LRP8	HGNC	ENSG00000157193	tier1	rs201950519	-	85	0	0.00	60	49	44.95	141	2	1.40	59	62	51.24
ENSG00000265803	0	genome.wustl.edu	37	6	158596076	158596077	+	R	INS	-	-	TGTGTATATATGTGTGTGTGTGTGTGTGTGTGTA			TCGA-SG-A6Z7-01A-12D-A32I-09	TCGA-SG-A6Z7-11A-21D-A32I-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	1a9b5304-f9e7-4b7f-9c10-bb5e0b659ce7	150e85f0-08f1-445f-86af-41a5bb0f3590	6	158596076	158596077	-	TGTGTATATATGTGTGTGTGTGTGTGTGTGTGTA	INS	ENSG00000265803	ENST00000580588	human	ensembl	74_37	+1	novel	rna	NULL	NULL	0.000:0.000	-	-	-	no_errors	AL590703.1	Clone_based_ensembl_gene	ENSG00000265803	tier1			22	0	0.00	5	0	0.00	22	0	0.00	5	0	0.00
MFHAS1	0	genome.wustl.edu	37	8	8748843	8748843	+	Missense_Mutation	SNP	C	C	T			TCGA-SG-A6Z7-01A-12D-A32I-09	TCGA-SG-A6Z7-11A-21D-A32I-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	1a9b5304-f9e7-4b7f-9c10-bb5e0b659ce7	150e85f0-08f1-445f-86af-41a5bb0f3590	8	8748843	8748843	C	T	SNP	MFHAS1	ENST00000276282	human	ensembl	74_37	-1	known	missense	c.1726	p.V576M	1.000	superfamily_P-loop_NTPase	pfam_Leu-rich_rpt,superfamily_P-loop_NTPase,smart_Leu-rich_rpt_typical-subtyp	-	no_errors	MFHAS1	HGNC	ENSG00000147324	tier1	-	-	43	0	0.00	35	4	10.26	22	0	0.00	6	0	0.00
MT-CO2	0	genome.wustl.edu	37	MT	8264	8264	+	Silent	SNP	C	C	T			TCGA-SG-A6Z7-01A-12D-A32I-09	TCGA-SG-A6Z7-11A-21D-A32I-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	1a9b5304-f9e7-4b7f-9c10-bb5e0b659ce7	150e85f0-08f1-445f-86af-41a5bb0f3590	MT	8264	8264	C	T	SNP	MT-CO2	ENST00000361739	human	ensembl	74_37	+1	known	silent	c.679	p.L227	NULL	NULL	pfam_Cyt_c_oxidase_su2_C,pfam_Cyt_c_oxidase_su2_TM_dom,superfamily_Cupredoxin,superfamily_Cyt_c_oxidase_su2_TM_dom,pfscan_Cyt_c_oxidase_su2_TM_dom,pfscan_Cyt_c_oxidase_su2_C,tigrfam_Cyt_c_oxidase_su2	-	no_errors	MT-CO2	HGNC	ENSG00000198712	tier1	-	-	89	0	0.00	14	2	12.50	6	0	0.00	0	0	0.00
PIDD	0	genome.wustl.edu	37	11	803545	803545	+	Missense_Mutation	SNP	G	G	T			TCGA-SG-A6Z7-01A-12D-A32I-09	TCGA-SG-A6Z7-11A-21D-A32I-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	1a9b5304-f9e7-4b7f-9c10-bb5e0b659ce7	150e85f0-08f1-445f-86af-41a5bb0f3590	11	803545	803545	G	T	SNP	PIDD	ENST00000347755	human	ensembl	74_37	-1	known	missense	c.338	p.A113D	0.888	NULL	pfam_Peptidase_S68_pidd,pfam_Death_domain,pfam_Leu-rich_rpt,pfam_ZU5,superfamily_DEATH-like_dom,smart_Leu-rich_rpt_typical-subtyp,smart_Death_domain,pfscan_Death_domain,pfscan_ZU5	-	no_errors	PIDD	HGNC	ENSG00000177595	tier1	-	-	35	0	0.00	19	4	17.39	30	0	0.00	2	1	33.33
ENSG00000221280	0	genome.wustl.edu	37	12	118604652	118604653	+	R	INS	-	-	ACACAC			TCGA-SG-A6Z7-01A-12D-A32I-09	TCGA-SG-A6Z7-11A-21D-A32I-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	1a9b5304-f9e7-4b7f-9c10-bb5e0b659ce7	150e85f0-08f1-445f-86af-41a5bb0f3590	12	118604652	118604653	-	ACACAC	INS	ENSG00000221280	ENST00000408353	human	ensembl	74_37	+1	novel	rna	NULL	NULL	0.002:0.000	-	-	-	no_errors	AC026366.1	Clone_based_ensembl_gene	ENSG00000221280	tier1			0	0	0.00	0	0	0.00	0	0	0.00	0	0	0.00
LCE2B	0	genome.wustl.edu	37	1	152659563	152659563	+	Missense_Mutation	SNP	C	C	A			TCGA-SG-A6Z7-01A-12D-A32I-09	TCGA-SG-A6Z7-11A-21D-A32I-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	1a9b5304-f9e7-4b7f-9c10-bb5e0b659ce7	150e85f0-08f1-445f-86af-41a5bb0f3590	1	152659563	152659563	C	A	SNP	LCE2B	ENST00000368780	human	ensembl	74_37	+1	known	missense	c.244	p.H82N	0.004	NULL	NULL	-	no_errors	LCE2B	HGNC	ENSG00000159455	tier1	-	-	67	0	0.00	160	18	10.11	1	0	0.00	2	1	33.33
LCE2B	0	genome.wustl.edu	37	1	152659592	152659592	+	Silent	SNP	C	C	T			TCGA-SG-A6Z7-01A-12D-A32I-09	TCGA-SG-A6Z7-11A-21D-A32I-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	1a9b5304-f9e7-4b7f-9c10-bb5e0b659ce7	150e85f0-08f1-445f-86af-41a5bb0f3590	1	152659592	152659592	C	T	SNP	LCE2B	ENST00000368780	human	ensembl	74_37	+1	known	silent	c.273	p.C91	0.532	NULL	NULL	-	no_errors	LCE2B	HGNC	ENSG00000159455	tier1	-	-	87	0	0.00	187	27	12.62	1	0	0.00	3	1	25.00
ZXDA	0	genome.wustl.edu	37	X	57936796	57936798	+	In_Frame_Del	DEL	CCG	CCG	-			TCGA-SG-A6Z7-01A-12D-A32I-09	TCGA-SG-A6Z7-11A-21D-A32I-09	CCG	CCG					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	1a9b5304-f9e7-4b7f-9c10-bb5e0b659ce7	150e85f0-08f1-445f-86af-41a5bb0f3590	X	57936796	57936798	CCG	-	DEL	ZXDA	ENST00000358697	human	ensembl	74_37	-1	known	in_frame_del	c.59_57	p.G20in_frame_del	0.010:0.009:0.008	NULL	pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2	-	no_errors	ZXDA	HGNC	ENSG00000198205	tier1			16	0	0.00	10	2	16.67	1	0	0.00	3	0	0.00
DSE	0	genome.wustl.edu	37	6	116757666	116757666	+	Missense_Mutation	SNP	G	G	A			TCGA-SG-A6Z7-01A-12D-A32I-09	TCGA-SG-A6Z7-11A-21D-A32I-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	1a9b5304-f9e7-4b7f-9c10-bb5e0b659ce7	150e85f0-08f1-445f-86af-41a5bb0f3590	6	116757666	116757666	G	A	SNP	DSE	ENST00000537543	human	ensembl	74_37	+1	known	missense	c.2092	p.D698N	0.998	NULL	superfamily_Chondroitin_lyas	-	no_errors	DSE	HGNC	ENSG00000111817	tier1	-	-	33	0	0.00	73	7	8.75	19	0	0.00	21	2	8.70